--- Log opened Sat Oct 14 00:00:55 2023
00:15 -!- acertain_ [sid470584@id-470584.hampstead.irccloud.com] has quit [Ping timeout: 255 seconds]
00:16 -!- acertain_ [sid470584@id-470584.hampstead.irccloud.com] has joined #hplusroadmap
00:22 -!- justanot1 [~justanoth@gateway/tor-sasl/justanotheruser] has joined #hplusroadmap
00:24 -!- justanotheruser [~justanoth@gateway/tor-sasl/justanotheruser] has quit [Ping timeout: 252 seconds]
02:17 -!- sphertext [~sphertext@user/sphertext] has quit [Quit: Textual IRC Client: www.textualapp.com]
03:34 -!- justanot1 [~justanoth@gateway/tor-sasl/justanotheruser] has quit [Ping timeout: 252 seconds]
04:15 -!- ike8 [12fdf2ee08@irc.cheogram.com] has quit [Ping timeout: 258 seconds]
05:19 -!- stipa [~stipa@user/stipa] has joined #hplusroadmap
05:37 -!- darsie [~darsie@84-113-55-200.cable.dynamic.surfer.at] has joined #hplusroadmap
05:56 -!- ike8 [12fdf2ee08@irc.cheogram.com] has joined #hplusroadmap
08:21 < docl> has anyone tried to solve the fentanyl crisis with drug delivery implants yet?
08:23 < L29Ah> what crisis?
08:27 < docl> https://twitter.com/garrytan/status/1713057087708856477
08:27 < docl> IDK, everyone's saying there is a crisis. I'm not plugged into drug culture enough to know. I've had one acquaintance die of it that I know of
08:28 < docl> apparently in san francisco it's a big deal
08:29 < docl> I think the basic problem is that it's effective at ultra small doses compared to other street drugs. So it's cheap to ship and widely used as an adulterant
08:29 < docl> cheap to ship = cheap to smuggle
08:29 < L29Ah> expanding manufacturing competition is the only way forward out of this cartel-enforced drug enshittification
08:30 < docl> yeah I concur
08:30 < docl> but it's not going to be deregulated any time soon. nor would legalizing it fail to result in a lot of people dying in the short term
08:33 < docl> a drug delivery implant though, that could probably work. it could auto taper to minimize discontinuation symptoms and cravings. people with a chronic pain condition could just get it refilled once a year or every 5 years.
08:36 < L29Ah> i don't recall anyone doing from LSD
08:36 < L29Ah> *dying
08:37 < L29Ah> and the implant doesn't address the psychedelic drug market, that is the point of the original twitter post
08:38 < docl> apparently they are dying from fentanyl-laced LSD now
08:38 < L29Ah> LSD doesn't reduce pain, it amplifies it, if anything
08:40 < docl> if you want LSD experience with the pain numbed you might combine it with a small dose of fentanyl (if you're insane enough to do fentanyl)
08:43 < docl> (I mean, insane enough to administer it to yourself without medical oversight -- it's very useful in the operating room)
08:50 < hprmbridge> nmz787> Fentanyl is nothing new, presumably the clandestine folks finally just figured out a protocol (stole it?)
08:50 < hprmbridge> nmz787> Seems like a real opportunity for personal detectors
08:51 < hprmbridge> nmz787> Like raman spectroscopy, xray fluorescence, mini mass spec
08:51 < hprmbridge> nmz787> Etc
08:51 < hprmbridge> nmz787> Something
08:52 < docl> upthread is this https://twitter.com/MissinginSf/status/1712916401353330817
08:53 < docl> apparently you can get free fentanyl test strips from the pharmacy. so the market niche is not entirely unfilled. we need more general tools though
08:53 < hprmbridge> nmz787> In some cities in some states
08:53 < docl> right. SF is its own beast
08:53 < hprmbridge> nmz787> There's plenty of other stupid or potentially deadly contaminants that aren't fentanyl
08:55 < docl> yeah. maybe this will influence drug culture in a direction that's more agressive on the testing
08:59 < docl> https://www.fda.gov/news-events/press-announcements/fda-approves-first-buprenorphine-implant-treatment-opioid-dependence
08:59 < docl> from 2016
09:04 < docl> pain med pumps have been a thing for a while, including fentanyl. apparently there have been overdoses from this: https://sci-hub.se/10.1097/AAP.0000000000000132
09:05 < docl> sounds like the older pumps were implanted at the base of the spine and delivered it in liquid form... yeah I could see that going awry at a certain rate
09:08 < docl> the buprenorphine implant is 4 small sudermal rods
09:09 < docl> "Probuphine® is a polymeric matrix composed of ethylene vinyl acetate and buprenorphine in the form of match-stick sized implants (26 mm × 2.5 mm) that are implanted subdermally and deliver buprenorphine over 6 months. The dose is equivalent to about 80 mg of buprenorphine, reliably released at a measured rate according to the matrix diffusion."
09:09 < docl> https://journals.sagepub.com/doi/10.1177/2045125316681984
09:12 < docl> something similar to that for fentanyl seems like it would be optimal, whether using it for addiction recovery or pain management
09:33 -!- L29Ah [~L29Ah@wikipedia/L29Ah] has left #hplusroadmap []
09:45 -!- TMM_ [hp@amanda.tmm.cx] has quit [Quit: https://quassel-irc.org - Chat comfortably. Anywhere.]
09:45 -!- TMM_ [hp@amanda.tmm.cx] has joined #hplusroadmap
10:59 -!- ike8 [12fdf2ee08@irc.cheogram.com] has quit [Ping timeout: 240 seconds]
11:29 -!- stipa [~stipa@user/stipa] has quit [Read error: Connection reset by peer]
11:30 -!- stipa [~stipa@user/stipa] has joined #hplusroadmap
12:59 -!- justanotheruser [~justanoth@gateway/tor-sasl/justanotheruser] has joined #hplusroadmap
13:51 -!- justanotheruser [~justanoth@gateway/tor-sasl/justanotheruser] has quit [Ping timeout: 252 seconds]
14:07 -!- justanotheruser [~justanoth@gateway/tor-sasl/justanotheruser] has joined #hplusroadmap
15:14 -!- stipa [~stipa@user/stipa] has quit [Ping timeout: 260 seconds]
16:11 < fenn> this seems really omnious https://blog.google/technology/safety-security/passkeys-default-google-accounts/
16:12 < hprmbridge> kanzure> no description of how it works?
16:16 < fenn> i can't find one
16:20 < fenn> mumble mumble public key cryptography and biometrics
16:21 < fenn> "None of our modern devices, laptops, smartphones or desktops — even those that use biometrics — can package biometric info and send it to the cloud" says google security techspert
16:32 -!- ike8 [12fdf2ee08@irc.cheogram.com] has joined #hplusroadmap
16:33 < fenn> so to summarize, their (fido/webauthn) explicit goal is to coerce everyone into carrying a personal surveillance device, in order to log in anywhere on the internet, in such a way that every other device is linked to your personal surveillance device
16:35 < fenn> google never clearly says they will use fido2
16:44 < fenn> here is the actual spec. it's too much for me to fully read and think about https://www.w3.org/TR/webauthn-1/
16:48 < hprmbridge> kanzure> oh it's just webauthn?
17:01 < fenn> maybe?
17:10 -!- ike8 [12fdf2ee08@irc.cheogram.com] has quit [Ping timeout: 240 seconds]
17:53 -!- L29Ah [~L29Ah@wikipedia/L29Ah] has joined #hplusroadmap
18:57 -!- L29Ah [~L29Ah@wikipedia/L29Ah] has quit [Ping timeout: 245 seconds]
19:00 -!- L29Ah [~L29Ah@wikipedia/L29Ah] has joined #hplusroadmap
19:07 -!- TMM_ [hp@amanda.tmm.cx] has quit [Quit: https://quassel-irc.org - Chat comfortably. Anywhere.]
19:07 -!- TMM_ [hp@amanda.tmm.cx] has joined #hplusroadmap
19:57 -!- justanotheruser [~justanoth@gateway/tor-sasl/justanotheruser] has quit [Ping timeout: 252 seconds]
22:17 -!- darsie [~darsie@84-113-55-200.cable.dynamic.surfer.at] has quit [Ping timeout: 240 seconds]
23:14 -!- justanotheruser [~justanoth@gateway/tor-sasl/justanotheruser] has joined #hplusroadmap
23:33 -!- justanotheruser [~justanoth@gateway/tor-sasl/justanotheruser] has quit [Ping timeout: 252 seconds]
23:45 -!- justanotheruser [~justanoth@gateway/tor-sasl/justanotheruser] has joined #hplusroadmap
23:58 -!- stipa [~stipa@user/stipa] has joined #hplusroadmap
--- Log closed Sun Oct 15 00:00:56 2023