--- Log opened Fri Oct 20 00:00:01 2023
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02:41 < hprmbridge> Eli> https://raw.githubusercontent.com/tairov/llama2.mojo/master/assets/llama2.mojo-demo.gif
02:41 < hprmbridge> Eli> mojo for mac is out
02:41 < hprmbridge> Eli> https://www.modular.com/blog/mojo-is-now-available-on-mac
02:46 < hprmbridge> Eli> Dr. Shanna Swan's book on Endocrine Disrupting Chemicals has terrified me. I would like to see more toxicology funding on microplastics.
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04:29 < hprmbridge> kanzure>  https://cdn.discordapp.com/attachments/1064664282450628710/1164888112783167498/image0.jpg?ex=6544d998&is=65326498&hm=e27776cd79d6ac1364e23278de4b15c0071494e643f80a04251536bdf68c06c3&
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06:55 < L29Ah> .t https://www.lifespan.io/news/why-long-lived-animals-are-needed-for-life-extension-studies/
06:55 < EmmyNoether> Why Long-Lived Animals Are Needed for Life Extension Studies
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08:32 < hprmbridge> nmz787> at least with compressing all the plastic together, you're pushing the microplastic issue out a ways
08:32 < hprmbridge> nmz787> reducing the surface area drastically, at the least
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09:14 < kanzure> https://github.com/kintesh/containerise https://addons.mozilla.org/en-US/firefox/addon/containerise/
09:21 < kanzure> https://addons.mozilla.org/en-US/firefox/addon/multi-account-containers/
09:22 < kanzure> more tab management https://news.ycombinator.com/item?id=37306058
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12:05 < hprmbridge> nmz787> libresilicon docs seem pretty decent
12:05 < hprmbridge> nmz787> could definitely use work
12:05 < hprmbridge> nmz787> at least with their organization
12:05 < hprmbridge> nmz787> lots of weird spelling mistakes or instances of  "??"
12:06 < muurkha> it's exciting
12:13 < hprmbridge> nmz787> just soooooo mannnnnyyyyyyy steppppppsssssss https://libresilicon.com/files/process/v1/HKUST_steps_dry.pdf
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13:40 < heath> https://wholeearth.info/
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13:45 < fenn> we were promised AGI, but we got emoji filename extensions
13:45  * fenn tips hat to peter thiel
14:00 < fenn> "Metformin, resveratrol, and nicotinamide riboside, which had all been previously found to extend life in mice, failed to replicate statistically significant results under ITP testing. (Interventions Testing Program.) ITP studies use UM-HET3 mice, a hybrid strain that lacks specific pathologies and is longer-lived than the standard Black 6 strain used in most mouse research."
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14:04 < fenn> rapamycyin, telomerase-related interventions, and genetic interventions related to IGF-1 and insulin signaling actually extended lifespan, rather than fixing pathologies
14:04 < fenn> and drugs that reduce heart rate
14:12 < ike8> _visual despair_
14:17 < fenn> who was the renaissance scientist obsessed with longevity who settled on eating coarsely ground bread, and lived longer than average?
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14:24 < ike8> No idea
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17:33 < L29Ah> HIIT reduces heart rate well :]
17:47 < hprmbridge> nmz787> fenn: gpt says "
17:47 < hprmbridge> nmz787> The Renaissance scientist you're referring to is likely Paracelsus, who had an interest in longevity and reportedly lived longer than average by eating coarse bread."
17:56 < Betawolf> I think it just made that up.
18:00 < Betawolf> Here's Paracelsus on bread:
18:00 < Betawolf> "It is a fundamental pillar upon which the physician should rest to give to each part of the anatomy the special thing that accords with it For the bread which the child eats has an anatomy similar to his own and the child eats as it were his own body : therefore each sickness in the anatomy must have its own accordant medicine He who does not understand the anatomy finds it difficult to act if 
18:00 < Betawolf> he be honest and simple ; but it is worse with those whose honour is small and whom shame and crime do not trouble. They are the foes of the light of nature... What blind man asks bread from God and receives poison? If thou art experienced and grounded in anatomy thou wilt not give a stone for bread. For know that thou art the father rather than the doctor of thy patients : therefore feed them as a 
18:01 < Betawolf> father does his child and as a father must support his child according to his need and must give him the food which becomes himself so must the doctor care for his patients. "
18:06 < Betawolf> There is some evidence that he did eat coarse bread at some point, but not by deliberate choice. In a different text: 
18:07 < Betawolf> "By nature I am not subtly spun, nor is it the custom of my native land to accomplish anything by spinning silk. Nor are we raised on figs, nor on mead, nor on wheaten bread, but on cheese, milk and oatcakes, which cannot give one a subtle disposition. Moreover, a man clings all his days to what he received in his youth; and my youth was coarse as compared to that of the subtle, pampered, and 
18:07 < Betawolf> over-refined. For those who are raised in soft clothes and in women's apartments and we who are brought up among the pine-cones have trouble in understanding one another well." 
18:08 < Betawolf> (also he only lived to 48 anyway)
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20:24 < fenn> paracelsus was a rad dude but not who i was thinking of, and doesn't seem to have had any interest in longevity either
20:25 < fenn> whoever i'm thinking of was fairly obscure
20:27 < fenn> .t https://www.jstor.org/stable/44443905
20:27 < EmmyNoether> HTTPError: HTTP Error 403: Forbidden (title:75)
20:29 < fenn> .wik luigi cornaro
20:29 < EmmyNoether> HTTPError: HTTP Error 404: Not Found (wik:100)
20:29 < fenn> .wik Luigi Cornaro
20:29 < EmmyNoether> "Alvise Cornaro, often Italianised Luigi (1484, 1467 or 1464 – 8 May 1566), was a Venetian nobleman and patron of arts, also remembered for his four books of Discorsi (published 1583–95) about the secrets to living long and well with measure and sobriety. /  Born in [...]" - https://en.wikipedia.org/wiki/Luigi_Cornaro
20:30 < fenn> "Friedrich Nietzsche criticized the work for mistaking the consequence with the cause, insisting that Cornaro's diet is not the cause of his long life, but rather that the cause of his long life - which Nietzsche gives as his slow metabolism - is the reason for his diet."
20:32 < fenn> at the age of 83, his health was good, he could perform most functions unassisted, and he had a wide circle of younger friends and correspondents. Cornaro also firmly condemned those with a live-fast-and-die-young mentality, stating that "They don't stop and consider the virtue of ten more years of active life, at a point where we've reached a high point of experience and wisdom, two things that
20:32 < fenn> can only be honed with time."
20:32 < fenn> He died at Padua at age 98
20:33 < fenn> or maybe 82, if you're a cranky wikipedia axe grinder
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--- Log closed Sat Oct 21 00:00:02 2023