--- Log opened Sun Dec 17 00:00:01 2023
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12:37 < hprmbridge> kanzure> masterjohn vs bryan johnson https://twitter.com/ChrisMasterjohn/status/1736166271517962392?s=20
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15:24 < hprmbridge> nmz787> Who's bryan johnson?
15:38 < L29Ah> rich immortalist
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15:45 < ike8> you don't know bj?
16:05 < hprmbridge> nmz787> nope, I live under a (silicon) rock
16:06 < hprmbridge> nmz787> I know masterjohn though, thanks to jrayhawk
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16:11 < L29Ah> who's masterjohn?
16:14 < hprmbridge> nmz787> he has a PhD in nutrition, I think
16:15 < hprmbridge> nmz787> and has done a lot of good work looking into diet and metabolism
16:15 < hprmbridge> nmz787> I'm sure jrayhawk can summarize better
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19:46 < jrayhawk> one of few sane people in the space
19:54 < Ashstar>  Bryan Johnson a rich immortalist that spends a lot of money and time on himself, he is obsessed with his image. Gets laser, botox takes over 100 supplements a day
19:54 < Ashstar> a regular Narcissus
19:56 < Ashstar> I pity anyone who has a relationship with him, he probably is the least fun guy to hang out with
19:57 < Ashstar> "hey, honey, want to go out to a party?" "Naw, rather stay home pop some supplements"
19:57 < Ashstar> take a veggie enema
19:58 < Ashstar> and read article in Longjevity Magaziene
19:59 < Ashstar> he's only 44
20:09 < Ashstar> he reminds me of a rich friend of mine, trying to keep the inevitable aging process away
20:10 < Ashstar> lives alone because he is too focused on immortality
20:11 < Ashstar> none of us will get out of life
20:11 < Ashstar> alive
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21:21 < muurkha> Ashstar: why are you even here
21:25 < hprmbridge> kanzure> https://finance.yahoo.com/news/jeff-bezos-elon-musk-human-170119555.html
21:26 < hprmbridge> kanzure> maybe I'll pitch "human gigafactory... but in space".
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22:37 < Ashstar> excuse me, what muurkha?
22:37 < fenn> the whole point of this channel is living forever, being narcissus, etc
22:38 < Ashstar> we can extend life, but there is either a trade off of quality of life, vs healthy happy involved life
22:38 < fenn> you don't have to be old to care about longevity
22:39 < fenn> please justify your argument
22:39 < Ashstar> I grew up at a place, if you have ever seen: "The Road to Wellville"
22:39 < Ashstar> like that
22:39 < Ashstar> I am a biologist biochemist
22:40 < Ashstar> I also, did my graduate dissertation on biological clocks
22:40 < Ashstar> of course I want to extend life, but with quality
22:41 < fenn> why must there be a trade off?
22:41 < Ashstar> sorry, if I sound a bit morose
22:42 < Ashstar> well, there is a point where you have to accept the normal ravages of entropy
22:43 < fenn> you're not even paying attention
22:43 < Ashstar> I guess I am jelous of those who can afford to spend buco bucks, but I also think you can supplement your ass off, if you don't exercise
22:43 < fenn> deathism is a curse that leads men to their graves
22:44 < Ashstar> well
22:44 < Ashstar> maybe, this is a tough time for me, right now
22:44 < fenn> it has been over a hundred years since we had the capability to do something about aging, but nothing much has been tried, simply due to a fatalist "oh well, guess we all die" current in society
22:44 < fenn> if any other ideology had caused the deaths of billions of people, we'd hear no end about how evil it is
22:45 < fenn> a million dollars here and there is a rounding error
22:45 < Ashstar> let us ask the hard question, why do we live?
22:45 < fenn> this is not an argument
22:46 < Ashstar> just to live?
22:46 < Ashstar> we have to have the knowledge that all life has term limits
22:46 < Ashstar> we should make the most of what time we have
22:47 < Ashstar> hey, if I had an extra million to spare, I probably would do all I could
22:48 < Ashstar> I just see a lot of people who miss part of it
22:48 < Ashstar> exercise, having a purpose
22:48 < fenn> do you really think we haven't heard all this before
22:49 < fenn> next you'll be telling me i have to make space for future generations
22:49 < Ashstar> your point?
22:49 < Ashstar> oh
22:49 < Ashstar> yes
22:49 < Ashstar> we have to move on
22:49 < fenn> move on then
22:49 < Ashstar> at some point
22:50 < Ashstar> but you misunderstand me
22:50 < Ashstar> I want to live healthy life, while I can
22:50 < Ashstar> have tried most my life
22:51 < Ashstar> I have a little knowledge
22:51 < Ashstar> I guess, this time of year makes me maudlin
22:52 < Ashstar> I grew up around those who sought to live long lives, at a health spa in Mexico
22:53 < Ashstar> I also, do believe that there has to be time outs from our eating
22:53 < fenn> it turns out that kale is not the elixir of immortality
22:53 < Ashstar> fasts, if done right
22:53 < Ashstar> can extend life
22:53 < fenn> caloric restriction gets you 10%, big whoop
22:53 < fenn> (less than that for humans)
22:53 < Ashstar> yeah
22:54 < Ashstar> for sure
22:54 < Ashstar> big criteria
22:54 < fenn> the interventions people are talking about are so miniscule that we have a hard time designing experiments to measure whether they are causing any benefit at all
22:55 < Ashstar> it is hard to isolate one thing
22:55 < Ashstar> it has to be holographic
22:56 < fenn> we don't actually know
22:56 < Ashstar> a lifestyle
22:56 < fenn> for some reason naked mole rats live a lot longer than other similar species
22:56 < Ashstar> of course not
22:56 < Ashstar> but caloric restrictions, for sure
22:57 < Ashstar> the naked mole rat is unique
22:57 < Ashstar> it is almost a Eusocial 
22:57 < Ashstar> species
22:57 < Ashstar> it has a lot of other things that are at play
23:00 < Ashstar> like they have a lot of social cohesion, helps w stress
23:01 < Ashstar> well developed social structure
23:02 < Ashstar> we have so much overexposure to cortisols, exercise really helps reduce that
23:02 < Ashstar> increase cellular respiration, ATP production
23:18 < Ashstar> seriously guys, sorry if you got the impression that this is not a big deal to me, shit, I spent my graduate research on understanding the biological clock
23:19 < Ashstar> Chronobiology
23:30 < fenn> it's obvious that one should wish for more wishes, and then wish for the wisdom to make good use of them
23:30 < fenn> in that order!
23:31 < fenn> it's no use having wisdom if you haven't got the wishes
23:39 < Ashstar> well, we do wish for our lives to be qualitatively good, to not suffer  also a long life that is not a slow painful crawl towards our end
23:39 < Ashstar> Im seeing the slow decline of my aunt
23:40 < Ashstar> it's tough to see
23:42 < Ashstar> it helps me focus on making my life qualitatively good, productive
23:42 < Ashstar> part of that is health
23:42 < Ashstar> of course
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--- Log closed Mon Dec 18 00:00:02 2023