--- Log opened Thu Jan 18 00:00:33 2024
00:07 < fenn> bah. "There isn't a specific term for starting ectogenesis at the three-month mark because the technology to perform this procedure doesn't currently exist."
00:07 < fenn> when has something not existing ever stopped anyone
00:10 < muurkha> literally every time they tried to do it
00:14 < fenn> we talk about things that don't exist all the time
00:16 < fenn> ""Explant" is a term used in tissue engineering to refer to the process of removing tissue from an organism and then culturing it in a controlled environment. However, it doesn't specifically imply that a fetus continues to live after being removed."
00:17 < muurkha> oh, I misunderstoos
00:17 < muurkha> *d
00:19 < fenn> i'm researching terminology
00:19 < fenn> "fetal transplant" shouldn't be used for artificial wombs, imho
00:20 < fenn> explant (medicine) To remove something, such as a medical device, that has been implanted. 
00:21 < fenn> technically true
00:21 < fenn> implant (intransitive) Of an embryo, to become attached to and embedded in the womb.
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00:44 < fenn> i think someone just made up this word "outplant" and put it in the dictionary, and then it experienced citogenesis. supposedly it's about external breast enhancements or medical devices worn on the body
00:46 < muurkha> ectoplant
01:07 < fenn> good suggestion. i will put it in the global suggestion box for making planet earth better
01:17 < fenn> done
01:18 < fenn> btw if anyone was wondering, the suggestion box is at the north pole post office across from santa's workshop
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03:31 < fenn> luddite bingo card https://rationalconspiracy.com/2020/07/24/why-your-invention-should-be-banned/
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08:01 < kanzure> is the bridge down?
08:02 < kanzure> how is it launched, again?
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08:22 < fenn> i don't know what happened. it spontaneously fixed itself just after you complained? huh?
08:26 < kanzure> wasn't me
08:26 < fenn> this is what i see, there's no other logging afaik https://fennetic.net/irc/hprmbridge_console_2023-11-17.txt
08:27 < fenn> seems like an issue on the IRC side, it always says that discord shard resume stuff
08:27 < kanzure> soul_syrup: what do you mean signal generation for cortical organoid stimulation? can't you just send whatever signal you want.
08:28 < fenn> you have to stimulate them with spike trains
08:28 < kanzure> okay well just use any oher signal generator
08:28 < kanzure> or do we not have any?
08:29 < kanzure> *any other
08:29 < fenn> the url actually has a [...] in it?
08:30 < fenn> god i hate discord
08:31 < fenn> https://github.com/Unlimited-Research-Cooperative/human-cortical-organoid-signal-analysis/blob/main/stimulation_experiments/neuromimetic_stimulation/main.ipynb
08:31 < fenn> there. i have no idea what this is but apparently it's the topic of discussion
08:35 < fenn> for future reference if i'm not around, instructions for running the bridge are in /home/fenn/Discord-IRC-Python/cmd.txt
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08:36 < kanzure> why not just use neurons? https://github.com/Unlimited-Research-Cooperative/Bacteria-Neural-Network
08:36 < fenn> bacteria are much easier to culture
08:37 < fenn> also potentially faster due to smaller cell volume
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08:38 < fenn> it's a compelling idea
08:38 < kanzure> why is there a separate git repository for each idea? https://github.com/Unlimited-Research-Cooperative/Human-Cortical-Organoid-Octopus there is nothing here to indicate any insertion of human cortical organoids into octopus.
08:39 < kanzure> fenn: but how would you get long-range connectivity with bacteria. i don't understand.
08:40 < fenn> pili or cell membrane geometry like in neurons
08:40 < fenn> https://en.wikipedia.org/wiki/Pilus
08:41 < fenn> https://en.wikipedia.org/wiki/Bacterial_nanowires
08:42 < fenn> here's where superkuh chimes in about the importance of the phase transition of the cellular membrane in the synaptic cleft, or something
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08:49 < fenn> "On 20 April 2020, researchers demonstrated a diffusive memristor fabricated from protein nanowires of the bacterium Geobacter sulfurreducens which functions at substantially lower voltages than the ones previously described and may allow the construction of artificial neurons which function at voltages of biological action potentials."
08:49 < fenn> https://www.umass.edu/news/article/researchers-unveil-electronics-mimic-human
08:52 < fenn> seems like they should be concentrating on making a useful thing first, rather than worrying about whether it can interface with mammal neurons
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09:00 < fenn> a better way to make informed policy decisions https://fennetic.net/irc/science%20court%20an%20institution%20for%20scientific%20judgement%20kantrowitz1967.pdf
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10:38 < fenn> chatgpt seems adamant that marvin minsky was not cryonically preserved, but rather was cremated
10:41 < hprmbridge> kanzure> "Extracorporeal liver assist device... An organ you use only temporarily gets around chronic rejection issue."
10:42 < fenn> but what can be done for those with too much bule
10:42 < fenn> bile*
10:42 < hprmbridge> Eli> my uncle, a gerontologist, got cryonically preserved. Not sure by which company
10:43 < hprmbridge> kanzure> there's only a few thousand patients, I'm sure you could just check the list. was his name steve?
10:45 < hprmbridge> Eli> his name was Les
10:46 < hprmbridge> Eli> MD PhD gerontologist for one of the California universities
10:47 < hprmbridge> Eli> He would interview the oldest people in the world. He said the thing they all had in common was a rigorous schedule. For example, wake up at the same time everyday. Do the same schedule. He showed me a video of him interviewing one of the oldest men in the world and the guy still work a suit everyday even though he was basically in hospice.
10:48 < hprmbridge> kanzure> so was Steve Cole (UCLA gerontologist,k(
10:50 < hprmbridge> Eli> ill need to ask my mom or aunt. I didn't realized he was cryonically preserved until a few years ago. I think my aunt just saw it as a belief that he didn't believe in the afterlife.
10:52 < fenn> Leslie Stephen Coles was also a visiting scholar in the computer science department at UCLA
10:55 < fenn> i would hope you'd know your own uncle's name
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10:56 < fenn> http://philsalin.com/index.html this guy died in 1991 and his webpage is still up. what's everyone else's excuse?
10:57 < hprmbridge> Eli> i met him only a few times when I was young. He lived in a different state than me.
11:03 < hprmbridge> Eli> ok, i asked my mom, but I'm thinking it might be that Les Coles guy. I see him interviewing Walter Breuning and that looks a lot like the video Les showed me
11:17 < hprmbridge> kanzure> lol did I seriously guess this
11:17 < hprmbridge> kanzure> wtf
11:17 < hprmbridge> kanzure> there's not nearly enough cryonics patients wtf
11:21 < L29Ah> https://sheldonbrown.com this guy died in 2008 and his webpage actually has plenty of really useful stuff
11:23 < hprmbridge> Eli> ya, im pretty sure it is that les coles guy. Everything checks out. I remember being told he was contracted by the CIA for awhile to analyze the health of foreign leaders based on video and images. He also had a few wives. And he looks a lot like how I remember him.
11:23 < hprmbridge> Eli> BTW, that Walter Bueuning guys is pretty incredible
11:23 < hprmbridge> Eli> https://www.wikiwand.com/en/Walter_Breuning
11:23 < hprmbridge> kanzure> yes I met his wife (well, widow) a few months ago
11:23 < hprmbridge> kanzure> she looks 50 years younger than he was
11:24 < hprmbridge> Eli> ya, haha, he went through women and had a young wife. From what I understand, he was not great to them and the wife didnt even want to know us because they thought we would be bad people too
11:26 < hprmbridge> Eli> ```In 1960, age 64, Breuning was diagnosed with colon cancer. It was successfully treated and the cancer did not return. Breuning did not have any other health issues until he broke his hip aged 108. He spent eight days in the hospital and was totally healed in 21 days.
11:26 < hprmbridge> Eli>
11:26 < hprmbridge> Eli> but continued eating two meals a day. He ate a big breakfast and a hearty lunch but skipped an evening meal, snacking on fruit instead. Breuning drank much water through the day plus a cup-and-a-half of coffee with breakfast and one cup with lunch. He got up every day at 6:15 am and had breakfast at 7:30 am. He then took a stroll around The Rainbow for exercise and could then be found sitting in
11:26 < hprmbridge> Eli> the lobby chatting with fellow residents and his many visitors.
11:26 < hprmbridge> Eli>
11:26 < hprmbridge> Eli> Overall, Breuning was in good health almost all of his life. His weight was around the same for the last 50 years of his life, 125–130 pounds (57–59 kg). Because Breuning was 5 feet 8 inches (1.73 m), his body mass index was around 19. For years Breuning took a baby aspirin every day, but he eventually gave that up, stating that he did not need it; from there on he took no medication. Breuning
11:26 < hprmbridge> Eli> believed another key to his longevity was keeping his mind and body active. He performed daily calisthenics almost to the end.```
11:26 < hprmbridge> Eli> ```
11:27 < hprmbridge> Eli> This guy was a biohacker before biohackers existed. Perfect chronobiology, intermittent fasting, actively fought inflamation, exercise, social activity, fantastic BMI.
11:28 < hprmbridge> kanzure> anyway the company was alcor, pretty sure
11:28 < hprmbridge> Eli> Somehow beat pancreatice cancer in the 60s. Somehow beat a broken him at age 108?!
11:29 < hprmbridge> Eli> pretty much only 2 choices right?
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11:30 < hprmbridge> kanzure> no there's also the russian one that got split up in a divorce (cryorus)
11:30 < hprmbridge> Eli> ah ok
11:30 < hprmbridge> kanzure> https://futurism.com/woman-accused-stealing-cryogenically-preserved-bodies
11:48 < hprmbridge> benjamin421> Does anyone know someone who has microfluidic piezo or peristaltic pumps in stock in the US for sub $200?
11:48 < hprmbridge> benjamin421>
11:48 < hprmbridge> benjamin421> 2-10ml/min ideally.
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12:03 < L29Ah> there are lots of peristaltic pumps on 3d printing websites, pretty sure some are sold, or at the very least you can order the parts
12:41 < hprmbridge> Eli> my mom got back to me, it was Leslie Steven Coles, MD, PhD
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12:44 < hprmbridge> Eli> wife named Laurie
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13:01 < hprmbridge> kanzure> yes I've been on his mailing listserv for at least 10 years
13:01 < hprmbridge> kanzure> it's still going, just run by someone else now
13:01 < hprmbridge> kanzure> george and aubrey and others chime in every now and again
13:02 < hprmbridge> Eli> actually, laurie was an older wife lol. apparantly got an upgrade or two since we last saw him
13:06 < L29Ah> > On March 31, 2011, Breuning was hospitalized in Great Falls for an unspecified illness. Then-Governor of Montana Brian Schweitzer visited him in the hospital on April 6 and 8, 2011.[28][29] He died peacefully in his sleep of natural causes at 3:30 pm local time on April 14, 2011.[30] 
13:06 < hprmbridge> kanzure> natalie is the widow i met.
13:06 < L29Ah> wtf is this
13:06 < L29Ah> "unspecified illness" "of natural causes"
13:06 < hprmbridge> kanzure> she would like help digitizing 30+ years of the GRG video archives
13:07 < hprmbridge> kanzure> https://grg.org/
13:10 < hprmbridge> Eli> whoa, never have seen this. Thankyou so much
13:15 < hprmbridge> kanzure> yes this was his group
13:33 < hprmbridge> Eli> Wait, she’s actively looking for help to digitize this? I have some video skills
13:33 < hprmbridge> kanzure> Yes
13:35 < hprmbridge> Eli> I’ll reach out to her. Ty 🙏🏽
13:38 < hprmbridge> Eli> Explaining cryonics to my Argentine friend https://cdn.discordapp.com/attachments/1064664282450628710/1197656218630639626/IMG_0915.png?ex=65bc0f45&is=65a99a45&hm=befd1c64273185c31fcdb4f242e02928ddf39caaab25feea39cee284ddba249a&
13:39 < hprmbridge> Eli> I feel like life extension will need some PR work
13:39 < L29Ah> it does
13:40 < hprmbridge> kanzure> send them https://waitbutwhy.com/2016/03/cryonics.html
14:16 < hprmbridge> Eli> her objections are not scientific in nature
14:19 < fenn> abre los ojos
14:19 < fenn> https://es.wikipedia.org/wiki/Abre_los_ojos_(pel%C3%ADcula)
14:25 < L29Ah> Eli: then http://www.skyhunter.com/marcs/GentleSeduction.html
14:55 < hprmbridge> kanzure> https://app.scholarai.io/home but I think this is only trained on abstracts.
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16:42 < hprmbridge> Eli> Im facing time and space complexity limits. Would it be possible to get a gen alpha tik tok summary
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17:58 < Ashstar> wow
17:58 < Ashstar> "we have developed an low-cost scanning tunneling microscope (STM) cost of 300 USD or 2000 CNY. The microscope is suitable for educational purposes and low-demand research imaging at the nanometer level"
17:59 < Ashstar> I almost bought an SEM
18:00 < Ashstar> TEM doing that
18:00 < Ashstar> wow
18:00 < Ashstar> interesting
18:01 < Ashstar> https://www.hardware-x.com/article/S2468-0672(23)00111-6/fulltext#%20
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21:43 < superkuh> Welp, libgen.is is back to the normal non-JS design. Yay.
21:51 < hprmbridge> kanzure> the lesson is, complain more
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--- Log closed Fri Jan 19 00:00:33 2024