| --- Day changed Thu Jan 28 2010 | ||
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| fenn | kevin kelly really liked my lifelog thingy | 01:49 |
|---|---|---|
| fenn | apparently he's been doing the 20 minute x 4 power naps for 15 years | 01:50 |
| kanzure | in person? | 01:54 |
| kanzure | kevin kelly is why i know you | 01:54 |
| fenn | ya i told him about skdb | 01:54 |
| kanzure | why are you getting to meet all the interesting people =[ | 01:56 |
| kanzure | well, at least blab about it | 01:56 |
| kanzure | s/it/him/ | 01:56 |
| fenn | he got all sidetracked about this "forever book" idea, which is a book that teaches you how to make books from dirt and plants | 01:56 |
| kanzure | right | 01:56 |
| kanzure | there was a post on kk.org about that | 01:57 |
| fenn | http://www.kk.org/thetechnium/archives/2006/02/the_forever_boo.php | 01:57 |
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| gearhacker | http://pastebin.com/m44577e04 | 02:52 |
| gearhacker | wobble gear generation script, doesn't work, if you can make it work, you win a cookie. | 02:53 |
| gearhacker | http://pastebin.com/d52a37afc | 02:57 |
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| ybit | bkero: what ip does openmanufacturing need to point to, it's pointing at 69.163.39.14 right now | 09:32 |
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| ybit | "many of the founders of iGEM, including Drew Endy at Stanford, Tom Knight at MIT, and DIYbio-rep Mac Cowell are heavily involved in or supportive of the DIYbio community. " | 09:47 |
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| ybit | http://hplusmagazine.com/articles/bio/diy-bio-growing-movement-takes-aging | 09:47 |
| ybit | is tom knight still involved, was it just the mailing list he ditched? | 09:47 |
| Utopiah | (might interest some people here http://seedea.org/buffering/OFF_THE_GRID.Smiley.DVDRip.avi available for 2 more hours) | 09:48 |
| ybit | Utopiah: what's the file size of that? | 09:53 |
| ybit | meh, nm | 09:53 |
| ybit | 454M | 09:54 |
| ybit | availaavailable for two hours? good. it will take me just over an hour to download it on this slow wireless connection | 09:55 |
| ybit2 | i forget the adl connection is slow | 09:56 |
| ybit2 | have to use the home connection for irc atm | 09:56 |
| bkero | ybit: done | 10:12 |
| ybit2 | thank you bkero | 10:34 |
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| bkero | Sorry that took so long. | 10:39 |
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| ybit2 | bkero: np | 12:39 |
| ybit2 | http://www.unreasonablefinalists.org/index.php?action=about_pro&proId=149 :: joseph jackson's group trying to raise money | 12:47 |
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| kanzure | "Direct Conversion of Fibroblasts to Functional Neurons by Defined Factors" | 18:22 |
| kanzure | bwahaha | 18:22 |
| gearhacker | neat | 18:24 |
| gearhacker | btw do you know anything about the barcelona fablab? | 18:24 |
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| kanzure | hey JayDugger | 18:41 |
| JayDugger | Hello, kanzure. | 18:41 |
| JayDugger | Thank you for posting that U of KY Open Design paper. I enjoyed reading it. | 18:42 |
| JayDugger | I took their point about open design combating obsolescence. A machine designed in the 1980s sat across the room from me when I read that passage. | 18:43 |
| kanzure | "took their point"? | 18:43 |
| JayDugger | Open design would have helped prevent much of the work on that machine. | 18:44 |
| JayDugger | Let me put it this way. That machine's original computer was a PDP-11. | 18:46 |
| kanzure | heh | 18:46 |
| JayDugger | The documentation was written at the beginning of the careers by people who have long since retired. | 18:47 |
| JayDugger | And--any performance tweaks mean editing assembly code. | 18:47 |
| JayDugger | The only good thing about it was truthfully telling my boss, "What do I know about one of those? I've never even seen a picture of one." | 18:48 |
| JayDugger | \/rant :) | 18:48 |
| drazak | kanzure: that sounds highly questionably | 19:05 |
| drazak | kanzure: fibroblasts are pretty mature/restricted | 19:05 |
| futuresoon | Recent work has shown that mouse and human fibroblasts can be reprogrammed to a pluripotent state with a combination of four transcription factors. This raised the question of whether transcription factors could directly induce other defined somatic cell fates, and not only an undifferentiated state. We hypothesized that combinatorial expression of neural-lineage-specific transcription factors could directly convert fibroblasts | 19:16 |
| futuresoon | into neurons. Starting from a pool of nineteen candidate genes, we identified a combination of only three factors, Ascl1, Brn2 (also called Pou3f2) and Myt1l, that suffice to rapidly and efficiently convert mouse embryonic and postnatal fibroblasts into functional neurons in vitro. | 19:16 |
| futuresoon | that's what they're claiming at least | 19:16 |
| drazak | oh, right | 19:20 |
| drazak | you need to make them IPSC's first | 19:20 |
| drazak | also do they show westerns and RTPCR showing gene and protein expression? | 19:21 |
| drazak | I'd guess they'd still show a lot of fibroblast genes | 19:21 |
| * fenn just had a nice interview with gary wolf for the NY times | 19:24 | |
| JayDugger | Oh? | 19:25 |
| fenn | re: self tracking (and everything else) | 19:25 |
| JayDugger | Kudos! I hope your points survive to publication. :) | 19:25 |
| kanzure | fenn: yeah i've met with gary a few times. nice guy | 19:34 |
| kanzure | he was totally psyched about andrew hessel | 19:34 |
| kanzure | gary wolf is with wired.com though, i thought | 19:34 |
| kanzure | o.O maybe he's switched sides | 19:35 |
| fenn | playing the field i guess | 19:36 |
| fenn | he and kevin seemed to be on good terms | 19:37 |
| * fenn grumbles about batteries | 19:43 | |
| fenn | off to ARdevmob! | 19:43 |
| QuantumG | http://singularityhub.com/2010/01/27/the-win-human-recorder-a-patch-to-monitor-your-health/ | 19:44 |
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| MrClif | Evening. | 21:20 |
| JayDugger | Good evening. | 21:21 |
| MrClif | Havn't been on in awhile looks to be pretty quiet tonight. | 21:22 |
| MrClif | Hey Bkero, and Randellgordon, We're doing pizza at PRI tomorrow, not a big deal just thought you'de like to know. :-) | 21:23 |
| MrClif | That goes for anyone else who dosn't mind a drive to Eugene OR. ;-) | 21:24 |
| * bkero sees how it fits on his calendar. | 21:24 | |
| MrClif | Yep, not a big deal, right now it's Marc, his Hacker Son Ian, Probably Brycen, and myself. | 21:26 |
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| JayDugger | Time to commute. Good night, all. | 22:23 |
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| gearhacker | Optimization of Fused Deposition Modelling (FDM) Process Parameters Using Bacterial Foraging Technique | 22:48 |
| gearhacker | hmmm... | 22:48 |
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| ybit | kanzure: uh.. | 23:42 |
| ybit | http://bio.cc/Bioinformics/papers/ | 23:42 |
| ybit | a lot of that is familiar looking | 23:42 |
| kanzure | well it should | 23:43 |
| kanzure | i put it there | 23:43 |
| ybit | it looks like they are mirroring you? | 23:43 |
| kanzure | they don't know they are mirroing me | 23:43 |
| ybit | :P | 23:43 |
| kanzure | *mirroring | 23:43 |
| ybit | is there other stuff on their site which isn't on yours.. | 23:43 |
| kanzure | everything in /Bioinformics/papers/ is me | 23:43 |
| kanzure | everything else is who the feck knows | 23:43 |
| ybit | wasn't there another site.. | 23:43 |
| kanzure | (but not me) | 23:44 |
| kanzure | there's lots | 23:44 |
| ybit | er, dir | 23:44 |
| ybit | on bio.cc | 23:44 |
| ybit | perhaps tat was it | 23:44 |
| ybit | s/tat/that | 23:44 |
| ybit | the sata drive is up and running | 23:44 |
| kanzure | glad to hear it | 23:44 |
| ybit | i'm not sure what magical creatured entered it last night, but the machine recognizes it just fine | 23:45 |
| ybit | grr at typos | 23:45 |
| futuresoon | #theamericanpirateparty and #theamericanpirateparty-webdev | 23:51 |
| futuresoon | adaptive political platform using genetic algorithms, condorcet voting, etc. | 23:51 |
| futuresoon | reddit style deliberative fora | 23:51 |
| futuresoon | they could even perhaps be convinced to put their weight behind something like SKDB? maybe? | 23:52 |
| futuresoon | what little weight that is so far? | 23:52 |
| ybit | maybe when then have weight | 23:53 |
| futuresoon | interesting group of people i have to say | 23:54 |
| kanzure | ybit: that made no sense | 23:54 |
| ybit | i won't ask | 23:55 |
| futuresoon | http://i.imgur.com/9bLjQ.png | 23:55 |
| ybit | a friend and i were tossing around a p2p sys for the gov a few years ago, i just recently sat down to think it through again | 23:55 |
| futuresoon | ybit: everybody has thought of this | 23:55 |
| futuresoon | kanzure: and it *does* make sense | 23:55 |
| ybit | every geek at least | 23:55 |
| futuresoon | ybit: they're considering changing the party name to People's Front of Judea :-) | 23:56 |
| futuresoon | as an ironic meta-commentary on the contentiousness of the name Pirate Party | 23:56 |
| ybit | that's funny, but if they are changing it because they want to be taken seriously, bad choice | 23:56 |
| futuresoon | well it's a monty python reference and the webdev team is all python | 23:56 |
| ybit | right, and didn't know that | 23:56 |
| futuresoon | also Open Party, Bull Moose Party, other possibilities | 23:57 |
| futuresoon | i pitched Open Source Manufacturing (OSM - "awesome") Party | 23:58 |
| ybit | open party ftw | 23:58 |
| ybit | or free party | 23:58 |
| futuresoon | there was some talk of American Party | 23:58 |
| ybit | or freedom party? | 23:58 |
| futuresoon | "because then the media would have to call us "The Americans"" | 23:58 |
| ybit | that works | 23:58 |
| ybit | haha, that's great | 23:58 |
| futuresoon | net neutrality, an end to corporate personhood | 23:59 |
| futuresoon | these are some of the rough outlines, but all that has to be hashed out | 23:59 |
| futuresoon | and ultimately it'll be done something like this (if the plan comes off) | 23:59 |
| futuresoon | you have deliberative forums, where people make issues to vote on | 23:59 |
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