2010-07-03.log

--- Day changed Sat Jul 03 2010
AJollyLifeive considered couch surfing, but never got around to it00:18
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JayDuggerGood morning, streety.01:11
streetymorning01:11
fenngood morning, eulenspiegel01:12
fenni finally figured out what this was http://www.flickr.com/photos/23882161@N03/galleries/7215762259877859901:12
fennthere's an awful photoshop of it that got stuck in my head for a few days01:13
fenner, last photo01:13
streetywithout the other photos I can imagine it would be difficult to recognise01:14
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brunsgenusWell, I was wanting to know what you all thought about taking the DNA of Turritopsis dohrnii and implementing it on a person using viral treatment? 06:41
brunsgenus^ anyone have any comments?06:41
kanzurehm06:42
brunsgenusi have other idea on how06:42
brunsgenusbut i wanna know someones opinion first06:43
kanzurestreety: yeah i never really knew why they bothered with the forum06:43
brunsgenusi know viral treatment is like russian roulette 06:43
kanzurebrunsgenus: no, viral gene therapy has improved06:43
kanzurehttp://designfiles.org/papers/gene-therapy/06:43
kanzure^ read up on it06:43
brunsgenusorly?06:43
brunsgenuslast i heard some kids red blood cells exploded lol06:43
brunsgenuswell that was the first attempt at it but yeah06:43
brunsgenuskanzure: what do you think of my idea, though06:44
kanzureit seems underdeveloped.. why would you take dna from 'turritopsis dohrnii'?06:45
brunsgenuswhenever that jellyfish is about to starve to death it breaks itself back down equivalent to what we were in the womb and makes more jellyfish06:48
brunsgenuskanzure: did you not know that jellyfish existed?06:49
kanzuremighty big leap of assumptions you just made there06:51
brunsgenusyeah i know06:51
kanzurehow'd you get from a jellyfish gerontology to wondering if i knew that jellyfishes existed?06:51
brunsgenusI dunno, you said the name in quotes06:51
brunsgenusAlso I have ADD06:52
brunsgenuslol06:52
brunsgenusSorry if I offended06:53
brunsgenusBut what do you think of my idea?06:53
kanzureit still seems underdeveloped06:54
kanzurewhat genes are you going to take out of the dna?06:54
kanzureand what are you going to do with them06:54
brunsgenushere we go, this is what i was wanting to look into06:54
brunsgenuswell the reason why I even said use it in viral treatment because, from what I have learned that is almost the only to make such a drastic change on an organism that is already developed and alive06:55
brunsgenusalso I havent found out what the genes were06:55
kanzure'make such a drastic change' yes but what is the drastic change that you want to implement?06:56
brunsgenusanother idea is in the 8 celled stage of development taking out the other 7 and putting this DNA in there and then activating it when the fetus is developing06:56
kanzuretalking about the jellyfish end-of-life-cycle is pretty vague.. can you be more specific about what you want to do06:56
brunsgenusoh06:56
brunsgenussorry I forgot to mention it all06:57
brunsgenuswell obviously you would have to do some modifying but basically when you hit x aging point you go back to x point in life and yes i know that makes even more questions but i am talking about more so skeletal tissue etc. not neurons06:58
brunsgenusneurons you have to do something else06:58
kanzure"you go back to x point in life" what do you mean by this? time travel??06:59
brunsgenusthats still not all but i wont remember till you ask06:59
brunsgenusx point in life meaning development06:59
brunsgenusLike eh say go back to the point after puberty 06:59
brunsgenusi mean that would be a good genetic marker06:59
kanzuremy guess is that you don't know what a genetic marker is :P07:00
brunsgenusnope07:00
brunsgenus:D07:00
kanzureso, what do you know, then?07:00
brunsgenusi know that i like reading and im majoring in biology and micro biology in college, then i have to do stuff after that but as of right now im an undergrad with no biology classes07:00
kanzurehave you ever had a biology class07:01
brunsgenusyes?07:01
kanzureokay, just had to ask07:01
brunsgenus:(07:01
brunsgenusi sound that stupid huh?07:01
kanzurewell, i like the idea of using something from the jellyfish07:01
kanzuredo you have any papers on those genes? or the name of the genes, etc.07:02
brunsgenusno, this is something i was doing like when i was 1307:02
brunsgenusi just came back to it recently07:02
brunsgenusi have been messing around with computers07:02
brunsgenusim bored with those now so i wanna do genetics again07:02
brunsgenusI might be able to gather material if you can specify what exactly you want07:02
brunsgenusotherwise I am going to gather a bunch of interesting-yet-useless information07:03
kanzurehttp://scholar.google.com/ go forth and search :)07:03
kanzureoh this is "the immortal jellyfish" stuff. righto07:03
brunsgenusalright thanks07:03
kanzureInduction of reverse development in two marine Hydrozoans http://www.ijdb.ehu.es/web/pdfdownload.php?doi=062152js07:04
kanzureyeah if you can find the piraino paper that will probably be revealing.07:05
brunsgenuswhat do you mean07:06
brunsgenusrevealing in what way07:06
kanzureinformative?07:07
brunsgenusit was a joke :/07:07
brunsgenusim bad at those07:07
brunsgenusthey make me laugh07:07
kanzurePiraino, S. et al. 1996. Reversing the life cycle: medusae transforming into polyps and cell transdifferentiation in Turritopsis nutricula (Cnidaria, Hydrozoa). Biological Bulletin 190: 302-312.07:07
brunsgenushttp://www.sciencepub.net/nature/ns0802/03_1279_hongbao_turritopsis_ns0802_15_20.pdf07:09
brunsgenushere07:09
brunsgenusI think this one is a different breed but does the same thing07:10
brunsgenusjust for a different reason07:10
brunsgenusyeah this one is after puberty reverts back07:12
brunsgenusi got it confused with erg i forgot the name, its big and long too07:12
kanzuretypo: 'organsism' on the first page07:12
brunsgenusHey maybe he didn't have a good teacher in school.07:12
brunsgenuslol07:13
kanzureor a spellchecker? was this a published article07:13
brunsgenussciencepub.net07:14
brunsgenuslol07:14
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brunsgenusBut this is what I am hoping to pursue after college, maybe sooner if I can get a group of people interested in it with me07:16
JayDuggerGood morning. No photoshopped lotus blossoms or Central European tricksters this morning?07:16
brunsgenushold on ill give you one07:16
brunsgenushttp://www.pxleyes.com/images/contests/flower%20heads/fullsize/flower%20heads_4b1ef999a56e9.jpg07:17
brunsgenusthere you go07:17
brunsgenusjaydugger ^07:17
brunsgenuskanzure; what do you think?07:18
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brunsgenuskanzure?07:23
kanzurebrunsgenus: so far it seems like this jellyfish is significantly understudied07:25
kanzureyou'll probably have to do a few whole genome sequencing studies or single nucleotide polymorphism (SNP) analyses to figure out how it's different from other jellyfish07:25
kanzureand then study molecular biology for a bit, etc.07:25
brunsgenus:(07:27
kanzurewhat's wrong with that?07:29
brunsgenusI don't have the resources to do genome sequencing studies07:30
brunsgenusI am just a small town girl07:30
brunsgenusliving in a lonely world07:30
brunsgenuslol07:31
kanzurewhat sort of resources do you think it takes?07:31
kanzurei mean, next year it's going to cost a hundred bucks07:31
brunsgenusIt takes money07:32
brunsgenusI just spent 50007:32
brunsgenusand have no job07:32
brunsgenuslol07:32
brunsgenusugh i am going to have to do freaking computer repairs again lol07:32
kanzurewhy is that funny?07:35
brunsgenusthe irony is funny07:35
brunsgenusI just fixed up an old computer and sold it for 500, then blew that away in a week07:35
JayDuggerAre the jellyfish about to go extinct? Are you? If not, then cultivate patience and work on them as fast you can.07:35
kanzure"about to go extinct" wouldn't make sense- he's talking about the 'immortal' jellyfish07:36
brunsgenusjaydugger07:36
brunsgenusI have ADD07:36
JayDuggerUnless you're in a race.07:36
brunsgenuslol07:36
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kanzurebrunsgenus: can you stop saying "I have ADD"? so does everyone else here.07:36
brunsgenusADD kids are impatient07:36
JayDuggerI don't.07:37
brunsgenus^07:37
brunsgenuskanzure you are wrong07:37
brunsgenusface.07:37
cluckjhah07:37
cluckjyou can learn to be patient07:37
brunsgenusI know07:37
kanzurecluckj: not really07:37
brunsgenus:(07:37
kanzurebrunsgenus: you should just get high on adderall (like i do)07:37
cluckjI did it :P07:37
brunsgenuskanzure i have been taking medication since the 2nd grade07:37
JayDuggerBut my girlfriend does, and that's provided plenty of opportunities for patience.07:37
kanzurein my case, it's ADHD07:37
brunsgenusprotip: It doesn't work anymore07:37
kanzurebrunsgenus: check if they changed manufacturers on you.. yeah.07:38
cluckjI started and quit taking meds for my ADD in high school07:38
JayDuggernice image of a lotus, BTW.07:38
brunsgenuskanzure: no, just to spite you07:38
brunsgenusjaydugger thank you, I thought you would like it07:38
brunsgenushaha07:38
cluckjI decided that I'd rather fight it with behavior modification than drugs07:38
kanzure"fight it"? why would you want to do that07:39
kanzurewouldn't you want to enhance it?07:39
brunsgenusI have decided that I am not going to participate in discussing ADD07:39
* brunsgenus sits quietly07:39
JayDuggerWhat's the argument for that?07:39
JayDuggerI've never heard one; I am curious.07:39
cluckjkanzure because I like being able to focus sometimes07:40
kanzureit's a common misconception that you can't focus.. just only on the things you actually care about.07:40
cluckjyep07:40
cluckjhyperfocusing07:40
brunsgenuskanzure is correct; its why i havent slept in 3 days07:41
brunsgenusshit sux07:41
cluckjhaha07:41
brunsgenuslol07:41
cluckjyeah exactly07:41
brunsgenusand yes, I have gotten to the point of hallucination 07:41
brunsgenusand im all sweaty which means I should shower soon07:42
cluckjkanzure you're doing it with medication, I do it with cigarettes, coffee and behavioral modification07:42
brunsgenuscluckj07:43
brunsgenusthats funny that you mention it07:43
brunsgenusbecause prior to me drinking coffee, using tobacco or trying to control myself I took medication07:43
cluckjhaha07:43
brunsgenusbut I have got to say, I took medication the other day and damn it helps a lot more obviously07:44
brunsgenusSo where would I go for genome sequencing?07:44
cluckjit's not exactly trying to control myself, it's just changing what I do when I need to focus on something07:44
brunsgenusI zone out if i dont want to do it, i learned to just do it but i wont be all there when im doing it07:45
cluckjI do whatever I don't want to be doing in a way that makes me want to do it :)07:45
brunsgenusoh so like, if you wanted to dip but didnt because of it making your teeth gross you put it between your toes07:46
brunsgenusbecause that works too07:46
brunsgenusyah know07:46
cluckjlol07:47
JayDuggerTime to run errands; goodbye, everyone.07:47
brunsgenusbi07:47
cluckjdoes it?07:47
cluckjcya07:47
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brunsgenusyou can do it under the armpit too07:47
brunsgenusanywhere with soft skin, really07:47
cluckjcool07:47
brunsgenusso where would I go for genome sequencing?07:47
cluckjdipping is really gross though07:47
brunsgenusI mean I just plop the jellyfish down and tell them to have at it?07:47
cluckjwhat kind of sequencing?07:47
brunsgenuscluckj you are really gross07:47
kanzureyou could buy your own machines, build your own, pay money, or get someone at a university or company to do it for you07:47
cluckjprobably, yeah07:48
cluckjbut I clean up nice07:48
brunsgenuswe will see about that07:48
brunsgenushttp://www.facebook.com/joncluck?ref=ts07:48
brunsgenuscluckj ^07:48
kanzurehaha you actually used that photo07:49
brunsgenuslol07:49
cluckjyep07:49
cluckjhell yeah, it's a great photo07:49
brunsgenusit looks matrix-e07:49
brunsgenusanyways, how much would a machine cost?07:49
kanzure$300 on ebay07:49
brunsgenusorly?07:49
kanzurebut those are older models07:49
brunsgenusso not that much07:49
brunsgenusoh07:49
kanzurethe new shit costs $25k+07:49
brunsgenusoh...uhm07:50
cluckjI put "haters gonna hate" as the caption because it reminds me of this: http://livingelpaso.files.wordpress.com/2010/03/haters.jpg07:50
brunsgenusAnyone wanna lend me 25k+?07:50
kanzurebrunsgenus: i might be able to lend that07:50
kanzurebut what are you going to do with it?07:50
brunsgenuscluckj it couldn't be becuase you like channing?07:50
brunsgenuskanzure persue what we were talking about earlier07:50
cluckjew07:50
cluckjdon't insult me07:50
cluckjI just love internet memes07:51
brunsgenusHey hey...I own a chan07:51
brunsgenuswell you can thank chans for internet memes07:51
brunsgenusDo you know what the first internet meme was?07:51
cluckjnope07:51
brunsgenushttp://media.photobucket.com/image/dancing%20baby/shanta824/DANCING_BABY.gif07:51
brunsgenusthis ^07:51
cluckjawesome07:52
brunsgenuskanzure, tbh I am wanting to get a group of people to work on this specifically07:52
kanzurethat is one hell of an ugly guy in that .gif07:52
brunsgenusI don't know who to get into contact with though07:52
cluckjspeaking of me being gross, brb07:52
cluckjI want some diy bio yogurt for breakfast07:53
kanzureso why do you think that this jellyfish is a better pursuit of resources than, say, stem cell therapies07:53
brunsgenusbecause it is already there, or as close as we can get to it. also there are less legal issues to work around than stem cells. anything involving that word gets media attention, the bad press, then they get shut down because of some lame ass politician 07:54
brunsgenusthe jellyfish has it out there already and since everything is so closely related on earth already i thought it would be the path of least resistance 07:54
kanzure"it is already there" well not really.. the genetics and developmental biology between jellyfish and humans are ridiculosuly complex07:55
kanzureit's certainly worth studying, yes07:55
kanzureand there might be something interesting in the genes07:55
brunsgenusWell yeah, like i said before it would need modification but it is an untapped potential resource07:55
kanzurebut it's definitely not a turn-key thing.07:55
brunsgenusHow old are you?07:56
kanzure2007:56
kanzureyou?07:56
brunsgenusI was about to say, this certainly doesn't look like a 20 year old in the picture07:56
brunsgenuslol07:56
brunsgenusI am 1907:56
cluckjmmm07:57
kanzurebrunsgenus: facebook sucks. just use my website. http://heybryan.org/07:57
kanzureoh wait. i turned off my server.07:57
kanzuresucks for you07:57
brunsgenus000chan.org07:57
brunsgenus^ my site07:57
brunsgenusshit sux07:57
kanzurebrunsgenus: you mean gurochan.07:57
brunsgenusguro guro07:57
kanzurewould you like some lotion for that burn?07:57
brunsgenusderp07:58
brunsgenusThe site went crazy last night after I tried to do some modifications so I had to wipe my most popular board07:58
brunsgenusHow much would it cost to get a university or something to do the genome sequencing?07:59
kanzurethe costs are dropping quickly07:59
kanzureten years ago it was about a million dollars08:00
kanzure5 years ago about $300k08:00
kanzure3 years ago about $100k08:00
kanzurethis year it's about $10k08:00
brunsgenusI am not going to have to wait years am i...08:00
brunsgenusoh damn08:00
kanzureand a few companies are trying to get it under $10008:00
brunsgenusI am not good with that, I will have to try and get it for cheaper08:00
brunsgenusyeah like IBM08:00
kanzurewhat about IBM? huh?08:00
brunsgenusthey claim they will be able to knock it down to 58k08:01
brunsgenusThey are joining forces with uhm08:01
kanzureaquaman?08:01
brunsgenuslol08:01
brunsgenussome company so that it can be knocked down cheaper08:01
brunsgenusobviously what is in it for them is the computer software/machine08:01
brunsgenusthats where they make their chunk of change08:01
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brunsgenusbuilding one myself might be the easiest and fastest solution08:04
brunsgenuskanzure: do you know of anyone who would want to research this with me?08:05
kanzurehttp://bits.blogs.nytimes.com/2010/03/20/would-you-pay-20-for-access-to-a-breast-cancer-cure/08:05
kanzurebrunsgenus: us in here :)08:05
kanzureand others. (brb)08:05
brunsgenusorly?08:06
brunsgenuskanzure: so we start at genome sequencing i guess08:08
brunsgenusI can set up an account for us to dump money into/accept donations08:08
brunsgenusto get the ball rolling08:08
brunsgenusArgentina v Germany game08:10
brunsgenusno sound08:10
brunsgenushttp://www.justin.tv/llion108:10
brunsgenuslive stream08:10
brunsgenushave fun08:10
brunsgenusif that doesnt work for you guys I have another link08:10
brunsgenusAnyone else watching?08:14
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brunsgenusi love corn dogs08:34
brunsgenusanyways.. kanzure am I right?08:34
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brunsgenusman it is pretty quiet in here...08:39
AJollyLifebrunsgenus: woo for add! :)08:42
brunsgenus:D08:43
AJollyLifei just woke up :)08:44
brunsgenusorly?08:44
brunsgenusI havent slept for 3 days08:44
AJollyLifeyeah, i tend to go to bed late, and wake up late08:44
AJollyLifemodafinil?08:44
AJollyLifeor just excited about stuff?08:44
brunsgenusI don't know08:44
brunsgenusI just didn't feel like sleeping08:44
AJollyLifeheh. its funny, but when im on add meds, i sleep more08:44
brunsgenusI have to remember to eat/sleep08:44
brunsgenusbecause i dont get hunger pains08:45
AJollyLifecause otherwise there is too much to research/learn/do and sleep/eating is boring08:45
brunsgenusand i dont feel tired08:45
AJollyLifeyeah, im mostly the same way08:45
brunsgenusi dont take medication08:45
AJollyLifebeen trying to force myself to sleep more though since its good for oyu08:45
brunsgenusi havent for years08:45
AJollyLifemedication certainly has its downsides08:45
AJollyLifei took it when i was in school, but dont these days08:45
brunsgenusyeah i try to force myself to sleep but it doesnt work out lol08:45
brunsgenusif i drink heavily i can go to sleep so well08:45
AJollyLifeyeah, i usually just keep doing stuff till i'm exhausted08:45
brunsgenusbut I have TMJ08:45
brunsgenusand so waking up sucks ass08:46
brunsgenusand i wake up from my teeth scraping together08:46
brunsgenusit suckkks08:46
AJollyLifetmj?08:46
brunsgenusor cracking sounds08:46
brunsgenusyeah08:46
brunsgenushold on08:46
brunsgenushttp://en.wikipedia.org/wiki/Temporomandibular_joint_disorder08:46
AJollyLifecluckj: looking at that photo, it would have worked better if i had you take off your namebadge :(08:47
AJollyLifethanks :)08:47
brunsgenusI am going to show you all my fb08:47
brunsgenusDONT LAUGH08:47
brunsgenus://www.facebook.com/Jrrdlkdl08:47
brunsgenusI am eating a paper icecream cone in that one08:48
AJollyLifewhy?08:49
brunsgenusbecause this girl and i were at chick file08:50
brunsgenusfilet08:50
brunsgenusw.e08:50
brunsgenusand she kept telling me to get icecream because she didnt want to be the only one eating one08:50
brunsgenusand i told her icecream was stupid08:50
brunsgenusand we argued08:50
brunsgenusand i caved in and made icecream08:50
brunsgenusand at it, it wasn't very good though08:50
brunsgenusate*08:50
brunsgenusmostly because it was paper 08:51
brunsgenusoh man...i need to stop talking08:53
AJollyLifelol08:54
brunsgenustrufax, though08:54
brunsgenusso did you read what I was talking about earlier?08:55
AJollyLifea bit08:55
brunsgenusdid it sound stupid?08:55
cluckjAJollyLife haha08:56
brunsgenus:(08:56
AJollyLifemeh, im not a bioguy, im a computer guy08:56
brunsgenusim kinda of a computer guy08:57
brunsgenussept i suck ass at programming08:57
brunsgenusso why is everyone quiet?08:58
cluckjI'm getting ready to go out08:59
brunsgenusim not08:59
brunsgenusi wanted to continue talking to kanzure09:00
brunsgenus>:| he left09:00
AJollyLifemeh, its a satruday, and this isnt a huge traffic channel09:01
cluckjhe's a busy dude09:01
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brunsgenusI wanna go shove a firecracker up a squirrels ass but there are none of them left.09:04
bdeskwat09:04
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brunsgenuslol09:04
AJollyLifeanyone here going to the singularity summit?09:08
brunsgenuscan i answer if i am not going?09:09
AJollyLifesure09:09
cluckjI think my friend grant is going to try to go09:09
brunsgenusi wanna go :(09:09
kanzurethe singularity summit looks lame this year09:11
brunsgenusi bet obama is going and will get an award09:11
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kanzurehi bdesk 09:14
bdeskkanzure: hey, how was scipy2010?09:14
kanzureit went well :)09:14
kanzurei presented on pythonocc09:15
kanzurethe enthought guys know their shit09:15
bdeskso it was well organized?09:15
brunsgenushai09:15
bdeskdid you see the bioinformatics talks?  I think galaxy was there.09:15
bdeskbrunsgenus: the eschaton is upon us.  make your time.09:16
kanzureno, i didn't see the bioinformatics talks :(09:17
bdeskhow many $$$$ of equipment do I need before pythonocc is useful for me?09:17
brunsgenusbdesk, eschaton?09:18
bdeskbrunsgenus: it is the singularity.  the end of times as we know them.09:18
brunsgenusOH SHI-09:19
* brunsgenus runs through time in reverse09:19
brunsgenusAHA09:19
kanzurebdesk: pythonocc can be installed on a regular laptop.. what are you talking about?09:20
brunsgenuswhy would you want pythonocc?09:20
bdeskkanzure: yes I know it is software, but the purpose of CAD is to design irl things, right?09:21
bdeski am not good at irl.09:21
kanzureoh are you wondering how to actually build something that you have a CAD file for?09:21
bdeskyes i guess.09:22
kanzurehonestly it depends on what the model is.. some things can be plastic molded, other things are meant to be cut from metals09:22
kanzureso let's say it's a plastic part09:22
kanzureyou could go to protomold.com and get it injection molded, you could go to ponoko or shapeways to get it "printed"09:23
kanzureor you could build your own cnc machine or 3d printer or whatever it is that you're trying to do09:23
bdeskok.09:23
kanzurebuild your own / buy your own, depending on your 'evolved' tastes. :P09:23
bdeskdoes reprap use this format?  reprap is the only 3d printer i've read about.09:23
kanzuresolid geometry cad is like source code, and what reprap uses is like a 'compiled binary object file' called STL09:24
kanzureso do your design in CAD, then convert the file to STL09:24
kanzureCAD -> STL is a very easy conversion.09:24
kanzureSTL -> CAD is ridiculously hard and you're talking a few grad students and a phd thesis :P09:24
kanzurepythonocc is better for doing programmatic CAD design09:25
kanzurenow if you want to just have a user interface or something, try heekscad09:25
kanzurehttp://heekscad.org/09:25
bdeskso with pythonocc i could write a python program that makes a widget design programmatically and then pythonocc will also do the conversion to STL?09:25
kanzureyes09:26
kanzureof course, you'll have to call model.to_stl() or something09:26
bdeskand then i could print it with reprap if the design is simple enough.09:26
kanzureyes :)09:26
bdeskand pythonocc and the CAD->STL converter does not need to know anything about reprap.09:26
kanzurecorrect but sometimes you want to go back and regenerate the STL Mesh09:27
kanzure*STL mesh09:27
kanzurelike maybe you want to increase the number of triangles, or something09:27
brunsgenustriangles are stupid >:/09:30
bdeskbrunsgenus: eternity is longer than you can imagine.  what finite comforts would you be willing to sacrifice to join us in this infinite utopia?09:30
brunsgenusI have an endless supply of hotpockets....09:30
brunsgenuswant those?09:31
kanzurebdesk: wtf are you talking about and why are you talking to brunsgenus about it? O_O09:32
brunsgenuskanzure is it bad to talk to me> :(09:32
brunsgenusYou think because I said it, therefore it needs to be discredited?09:33
brunsgenus:(09:33
AJollyLifexena reruns and hotpockets?09:33
bdeskbrunsgenus: a true cornucopia awaits.09:33
brunsgenus:D09:34
bdeskbrunsgenus: imagine a post-scarcity society.09:34
brunsgenuscheeseburger hotpockets....AS FAR AS THE EYE CAN SEE09:34
kanzurebrunsgenus: no, i don't think it's bad to talk to you09:35
kanzureit just doesn't make sense to me09:35
brunsgenusoh09:36
brunsgenusmy teeth hurt09:36
brunsgenusI want a fag09:36
bdeskkanzure: you have made irl widgets with pythonocc?09:37
brunsgenuslol i have a retainer09:40
brunsgenusi just took it out09:40
brunsgenusand spit got on my mousepad09:40
brunsgenusfuck09:43
brunsgenusugh09:43
brunsgenusI just got tricked into going to dinner...09:43
brunsgenusdammit....now i have to buy a bday present09:44
brunsgenuswhy is it no one in here is admin or operator or anything?09:52
kanzurefreenode doesn't want an operator for this channel09:56
brunsgenuswhy09:58
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bdeskPeople will be free to devote themselves to activities that are fun, such as programming, after spending the necessary ten hours a week on required tasks such as legislation, family counseling, robot repair and asteroid prospecting.10:10
brunsgenusif you guiz wanna join an irc that is fucking weird (my irc)10:14
brunsgenusirc.789chan.org #000chan10:14
brunsgenushttp://000chan.org/b/src/127817731136.gif10:15
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kanzurehttp://bookhling.wordpress.com/2010/07/03/8bit-tools-of-science/11:05
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bdeskkanzure: what is this "We already have beta versions of synthetic biology CAD program that undergraduates regularly use for their school assignments and private projects"11:16
kanzurelots of bullshit11:18
kanzureclothocad, for instance.. it's really not CAD11:18
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bdesk"Among many possible top-level explanations of Clotho, one of the simplest is the "Clotho Data Structure"-centric view. In this view, biological part data is passed back and forth between Clotho components and to files and databases outside Clotho."11:33
bdeskTheir project release was 2008 version 1.0 with no updates or source code repo.  If their selling point is their translations among data formats, then they will have to release a lot more often than this.11:35
bdeskhttp://clothocad.sourceforge.net/wiki/images/4/42/SynBioToolLandscape.png11:40
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kanzureyou know, power rangers was pretty terrible when it came out: http://www.youtube.com/watch?v=AkRvn0pXTiw13:44
kanzurebut this just explained everything to me: http://www.youtube.com/watch?v=sIwmbOoNsX013:44
kanzurealso explains the mecha fixation13:44
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brunsgenushai16:17
pmetzgero hai.16:21
brunsgenuswater u doin16:21
pmetzgertakin lik a lolcat.16:21
brunsgenuswat....16:23
brunsgenuslolcat...16:23
brunsgenus..jesus....16:23
pmetzgerloljesus iz diffrent16:24
brunsgenuslol u gay16:24
bdeskIN MAH YOUNGR AN MOAR VULNERABLE YEERS MAH FATHR GAEV ME SUM ADVICE DAT I'VE BEEN TURNIN OVAR IN MAH MIND EVR SINCE.  "WHENEVR U FEELZ LIEK CRITICIZIN ANY WAN," HE TOLD ME, "JUS REMEMBR DAT ALL TEH PEEPS IN DIS WURLD HAVEN'T HAD TEH ADVANTAGEZ DAT U'VE HAD."16:24
brunsgenuswat16:24
bdeskteh great lolcatsby16:25
brunsgenus>lolcat is not cool16:25
brunsgenuslol16:25
brunsgenusthough i do have a lulcat board on my chan16:25
brunsgenusit autophilters all the words into catspeak16:25
brunsgenusyou just have to get the dialect correct16:25
pmetzger<brunsgenus> on my 4chan.16:25
brunsgenus>on my 000chan16:26
pmetzgerlolcats are the best thing since sliced plasmids.16:27
brunsgenushttp://000chan.org/chz/16:27
kanzureyou guys are morons.16:28
kanzurejust saying.16:28
brunsgenus:(16:28
brunsgenusi has sad16:28
pmetzgeri can haz restriction enzymez?16:28
bkerono restriction enzymez 4 u16:29
bkerokanzure: am I morons?16:29
bdeski'm installing R on my other computer.  would a moron install R?16:29
bkeroYes16:29
pmetzgerI'm reminded of the line from "A Fish Called Wanda"16:30
brunsgenusI am installing ultimate hacking web browser16:30
brunsgenusaka internet explorer16:30
brunsgenusis that srupid?16:30
bdeskpmetzger: that's what i was going for :D16:30
brunsgenusstupid*16:30
bdesk"yes they would bdesk, they just wouldn't know how to use it!"16:30
pmetzger"Apes don't read philosophy" "Yes they do Otto, they just don't understand it." 16:31
pmetzgerR irritates me, but it is a good tool.16:31
pmetzgerthe syntax is irritatingly close to rational, but it is nutty so much of the time...16:31
pmetzgerif only it sucked more consistently or failed to suck more consistently.16:32
bdeskyes it is annoyingly good.16:32
pmetzgerwhen I was doing pchem lab, we had this really neat experiment which took ten minutes for the experiment and then weeks for the data crunching16:32
pmetzgerwe took the uv/vis spectrum of gaseous I2 and then figured out all these properties of I2 from it.16:33
pmetzgerI used a set of scripts (including some R) and got better accuracy than the handbooks have.16:33
pmetzgerthe other people in the class used spreadsheets and laboriously did everything by hand. they never got anywhere near to what I did.16:34
pmetzgerand I spent less time.16:34
pmetzgerI even did automated peak finding.16:34
bdesknice16:34
kanzurepmetzger: to be fair, the bar was set pretty low..16:34
bdeskwait how do you know your results are better than the handbook?16:34
kanzurei've been in situations like that.16:34
pmetzgerbdesk: because I calculated my error.16:34
brunsgenusAubrey de Grey is a pretty cool guy16:35
pmetzgerthe handbook data was all from the 1960s/1970s, and done on equipment that wasn't nearly so good.16:35
brunsgenusI am messaging him on fb lol16:35
kanzurebrunsgenus: aubrey responds to just about everyone.16:35
pmetzgerAubrey is a good chap, yes.16:35
pmetzgerkanzure: the bar was set low?16:35
brunsgenushe is pretty cool16:35
bdeskif aubrey de grey spends his time responding to people who are naked in front of their computer eating cheetos and talking like a lolcat then how does he have time to research immortality?16:36
pmetzgerI've never seen a man who loves his afternoon beer as much as him...16:36
pmetzgerbdesk: cloning.16:36
kanzurebdesk: he doesn't do research16:36
kanzureit's primarily the students and labs that do it16:36
pmetzgerkanzure: he does. he reads a vast amount of literature.16:36
pmetzgerhe just doesn't do any lab work, all theory.16:37
kanzureno he doesn't read that much16:37
kanzurehave you seen his bibliographies?16:37
kanzureand compared them to what's actually out there16:37
kanzurei mean, yes, he writes papers16:37
kanzurebut the bulk of his literature is from earlier16:37
pmetzgerkanzure: well, no matter what obscure paper I bring up with him, he's always read it and remembers the contents better than me. :)16:37
kanzurewhich btw i zipped up here: http://heybryan.org/transhuman/Aubrey.zip16:37
pmetzgerhe does know his stuff very well.16:37
pmetzgerand he seems to spend a lot of time keeping up with the literature.16:38
pmetzgerI have my doubts on WILT but I'm not an area specialist. I'm entirely self taught in molbio.16:41
pmetzgerbig lacunae in my background.16:41
bdeskwilt chamberlain?16:41
pmetzgerWILT.16:41
pmetzgeranti-cancer strategy aubrey has proposed.16:41
bdeskah16:42
bdeski am trained in molbio but i don't know much about transhumanism16:43
pmetzgerthere isn't much to know about transhumanism.16:43
pmetzgerand aubrey's research isn't into transhumanism, it is into life extension. :)16:43
bdeski see16:44
pmetzgertranshumanism just means the notion of using technology to go beyond what humans can naturally do (or even to replace the biological substrait)16:45
AJollyLifeid rather have money spent on antiaging/life extension than transhumanism personally16:45
pmetzgersubstrate16:45
pmetzgerbut it is an idea, it isn't a research topic.16:45
bdeskliving longer goes beyond what humans can naturally do.16:46
pmetzgerthe research is into things like AI, life extension, augmentation, uploading, etc.16:46
bdeskbut w/e the distinction is not important to me.16:46
pmetzgerliving indefinitely is certainly not something normal humans can do.16:46
bdeski see that he was the flybase db admin16:46
pmetzgerat one point.16:46
pmetzgerday job.16:46
pmetzgerbbl, going for a bike ride before it gets dark.16:47
bdeskkbye16:47
bdeski'd rather have money spent on flybase than antiaging/life extension personally.16:49
kanzure"Your Austin Meetup Calendar: 484 Meetups this week!16:49
kanzurewell that's useless..16:49
kanzurebdesk: there are lots of youtube-aubrey videos16:49
bdeskkanzure: maybe you could convince them to all meet in one stadium at the same time.16:49
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fennthe first internet meme was "this page is under construction"16:52
* fenn snickers at the idea of "the first internet meme"16:52
fennoh, he left16:54
fenn(praise be to his noodly appendage)16:55
kanzurefenn: did you know that power rangers was japanese?16:57
kanzurei'm totally perplexed as to how i could miss that..16:57
ybitthat changes everything, japanese power rangers17:07
bdeskso is there a list of the projects that people in this channel are involved with?  i'm from academia and I want to see if i'm missing anything cool.17:11
bdeski see http://www.acceleratingfuture.com/wiki/Hplusroadmap_wiki17:12
kanzurethere's no master list, no.. but there's a master todo list http://designfiles.org/skdb/doc/proposals/trans-tech.yaml17:12
kanzurebut now that i look at it, the todo list needs some updating17:12
kanzurebdesk: i used to host hplusroadmap-wiki ("biohack") on heybryan.org until i lost the hdd with the mysql database17:12
kanzurei supposedly still have the hdd somewhere in a closet.. uh..17:12
bdeskok thanks17:13
kanzurebdesk: if you pester us, we'll assemble a list17:13
ybitno more lists plz17:14
kanzurehuh?17:14
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ybiti'm tired of making a list of my projects :P17:14
ybitthink what we need is a website that gets people up-to-date on all the projects17:15
kanzureoh boy.. yet another website17:15
ybityup17:15
kanzurewhy not just a .txt file17:15
ybityou can make it easier for people to navigate with html17:15
kanzureit's a list, ybit..17:16
ybiti suppose17:16
ybitanywho17:16
ybitbdesk: any particular field you are interested in?17:16
bdeskno i was just wondering which projects are active.  i assume there are a ton of inactive projects for each active project.17:17
ybityou would be correct, sir17:19
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brunsgenusDoes anyone have any theories on biological immortality?17:31
bdeskbrunsgenus: aubrey de grey17:31
bdeskWILT17:31
brunsgenusanother question17:34
brunsgenusfucking magnets, how do they work?17:34
kanzurevirtual photons17:34
kanzure(ask feynman)17:34
brunsgenushttp://www.youtube.com/watch?v=RQWksKNrJm017:34
brunsgenus^ fucking magnets how do they work?17:34
brunsgenuskanzure17:35
brunsgenusplease watch that17:35
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brunsgenusstreetyl17:36
brunsgenusi have a question, please try to answer it after the video17:36
brunsgenus^ fucking magnets how do they work?17:36
brunsgenushttp://www.youtube.com/watch?v=RQWksKNrJm017:36
brunsgenusmagic everywhere in this bitch17:38
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bdeskhttp://www.cs.uku.fi/~katajama/youwouldnt/xyz.gif18:05
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kanzurebdesk: i would..18:09
bdeskskdb has an unfortunate google profile18:12
kanzureyeah i'm no good at naming shit18:13
bdeski think it's fine, at least the project names are not blatantly scatological.18:16
kanzurescat knowledge db, yo18:17
pmetzgermoo18:20
pmetzgerbdesk: I'm an academic18:20
pmetzgerso much for my bike for a couple of days. cable to the gear hub broke. :|18:20
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brunsgenuscluckj: much like cancer cells, some of the cells present in Turritopsis dohrnii are able to selectively turn certain genes on or off and allow for the genetic programs that were present in earlier stages of the life cycle to be reactivated.19:10
brunsgenusRead more at Suite101: The Immortal Jellyfish: Turritopsis Dohrnii http://fishinsects.suite101.com/article.cfm/the-immortal-jellyfish#ixzz0sfwhNIBx19:10
pmetzgerif only we were jellyfish.19:10
pmetzgerbut then we'd have more trouble using the internet.19:11
brunsgenusI am a jellyfish19:11
pmetzgerI had suspected.19:11
brunsgenusYou had better watch out, or else I will sting you19:13
pmetzgerThanks. I will remain perpetually on guard for that eventuality.19:14
* brunsgenus edges towards pmetzger 19:14
* brunsgenus raises tentacle.....19:15
* pmetzger removes a cuisinart and a copy of "how to cook jellyfish 800 different ways" from his backpack.19:15
* brunsgenus glares at pmetzger19:15
brunsgenusyou have won this round fair human...19:16
pmetzgerthere are advantages to being at the top of the food chain.19:16
* brunsgenus strings pmetzger 19:16
AJollyLifelike not having other things eat you?19:16
brunsgenusYou have 10 minutes to live19:16
brunsgenusspend it wisely.19:16
bdeskevery cell selectively turns certain genes on or off.  this is what transcriptional regulation is.  i guess they are talking about cell 'potency'.  also i wonder if the transdifferentiation also re-elongates the telomeres.19:16
pmetzgerstrangely, I feel just the same as before.19:16
brunsgenus"Turritopsis undergoes cycles of de-development (return to a pre-adult state, which means it has no long-lived non-dividing cells. We rely on such cells for brain function among other things. Thus, even if we understood the genetic basis of how Turritopsis does ewhat it does (which we don't), we would not want to use it on ourselves. " -Aubrey de Grey19:17
pmetzgerthey probably get cancers, too.19:17
pmetzgerthough they might have unusually good mechanisms to stop that.19:18
pmetzgerit is generally difficult to avoid cancers if you last long enough though.19:18
bdeskalthough de-development reverses one aspect of aging, there are other aspects of aging that this might not address.19:18
brunsgenusMy friend was talking about studying artificial cancer aimed at neurons in order to make the concentrations of neurons higher in certain regions of brain19:18
pmetzgerthat's nice.19:19
bdeskcool19:19
bdeskwell cool for the mice but i wouldn't want it yet19:19
brunsgenuswell, what do you all think about it....19:19
pmetzgerIt sounds like gobbledygook. :)19:19
brunsgenuslol19:19
brunsgenusI feel bad for mice19:20
brunsgenusI have two ferrets19:20
brunsgenuslol19:20
bdeskdo the ferrets eat mice?19:20
brunsgenusThey eat ferret food >:|19:20
bdeskbut in the wild they eat mice right?19:20
brunsgenusI don't think so19:20
pmetzgerdo ferrets get artificial brain cancers to increase the number of neurons in their brains?19:20
brunsgenusI saw my ferret eat a cockroach one time19:20
pmetzgerthey eat mice.19:21
brunsgenusnuh uh19:21
brunsgenusmine dont19:21
pmetzgerin general.19:21
pmetzgermice, voles, rabbits.19:21
pmetzgermuch like cats.19:21
brunsgenusmy cats eat catfood19:22
pmetzgerI'm sure they do.19:23
pmetzgerlater.19:24
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bdeskhttp://en.wikipedia.org/wiki/Ferret_legging19:26
brunsgenusWHAT19:27
brunsgenuslol19:27
brunsgenusI have a ferret in my pants.19:27
brunsgenushttp://openwetware.org/images/3/3d/SB_Primer_100707.pdf19:42
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kanzurebdesk: see pm20:01
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ybitwhere's part 2 and 3 to that?21:04
ybitnice find br21:04
ybiter.., guess he left since tabbing didn't work21:05
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brunsgenusBROCK LESNOR WON21:17
brunsgenusFUCK YES21:17
ybitbrunsgenus: do you know if 2 or 3 had been made?21:22
ybitof the synbio primer21:23
ybit+part 2 or 321:23
brunsgenusno clue21:24
brunsgenusCan you fill me in?21:24
brunsgenusybit ^21:26
ybit[15:33:31] <brunsgenus> http://openwetware.org/images/3/3d/SB_Primer_100707.pdf21:27
brunsgenusoh I was reading this earlier21:28
brunsgenuseh21:29
brunsgenusI don't think 2 or 3 are on there21:29
brunsgenusonly 121:29
ybitgoogle says the same21:29
brunsgenusI wanna buy the Turritopsis 21:31
brunsgenusybit when do you think these might be released21:32
ybitdunno, probably best to contact the authors21:32
brunsgenusif i can get a name I can get a phone number21:33
brunsgenusgive me a sec21:33
brunsgenuscome to think about it....calling someone randomly to ask them this question seems like a bad idea21:34
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