| --- Log opened Wed Dec 15 00:00:08 2010 | ||
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| kanzure | http://www.lifetechnologies.com/news-gallery/press-releases/2010/life-techologies-lauches-io-pgm-sequecer.html | 02:33 |
|---|---|---|
| kanzure | that link sucks.. | 02:34 |
| kanzure | http://www.lifetechnologies.com/content/lifetech/en/home/about-life-technologies/grand-challenges.html | 02:34 |
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| kanzure | hm nope.. it doesn't even list the challenges | 02:35 |
| kanzure | MrClif: no i'm not still up | 02:54 |
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| JayDugger | Good morning everyone. | 06:18 |
| Utopiah | I listened to http://www.franceculture.com/emission-le-champ-des-possibles-les-imprimantes-3d-vont-elles-remplacer-les-usines-2010-12-10.html yesterday and they mentionned http://www.organovo.com (already shared here) but also a (french I think) startup dedicated to bringing 3d printer to the masses by allowing shared design on a website, I didn't find its name so far though | 06:20 |
| archels | http://www.kurzweilai.net/distributed-biological-computation-imitates-logic-gate-circuits | 06:32 |
| archels | A one-bit adder with carry? *chuckle* | 06:32 |
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| archels | kanzure: "May be able to provide funding and a work space"? For what, building an MRI machine? | 07:06 |
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| archels | also lol @ out-of-office autoreply to e-mail lists. | 07:17 |
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| kanzure | hi jmil | 08:08 |
| kanzure | venter's stuff was oligonucleotide-synthesized, as i recall.. | 08:09 |
| kanzure | "Epoch of Plasticity: the metaverse as a vehicle for cognitive enhancement" http://www.atypon-link.com/INT/doi/pdf/10.1386/mvcr.1.1.69_1 | 08:17 |
| kanzure | that's natasha's latest.. weird.. article | 08:17 |
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| kanzure | "Counter Biology" http://danielgrushkin.com/images/articles/Articles_Volume_Interview.pdf | 08:44 |
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| jmil | kanzure: ah interesting | 09:05 |
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| kanzure | jmil: unless you read it more thoroughly than i did-- it's entirely possible that i'm talking out of my ass | 09:12 |
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| jmil | i never actually read it, just heard about it and thought they said they had a new way to do something in that paper | 09:23 |
| kanzure | there were many novel things in that paper and the previous papers, | 09:23 |
| kanzure | like transplanting entire chromosomes or chemically constructing chromosomes | 09:24 |
| MrClif | Has anyone here started a hackerspace / fab lab recently? I'm curious how that is going. | 09:24 |
| jmil | coolio | 09:24 |
| jmil | MrClif: ya we have Hive76 | 09:25 |
| jmil | started last year | 09:25 |
| jmil | it's going great! | 09:25 |
| MrClif | cool. | 09:25 |
| jmil | some growing pains but we are trying to get 501c3 status in the next year or so | 09:25 |
| jmil | it's a very slow process | 09:25 |
| kanzure | jmil: atx hackerspace opted to be an llc first and then go for 501c3 (they say it's easier that way) | 09:25 |
| MrClif | is there a site where I can read up on it? I'm toying with the idea of starting one in Eugene. | 09:26 |
| kanzure | MrClif: http://hackerspaces.org/ :P | 09:26 |
| kanzure | MrClif: you mean portland? | 09:26 |
| kanzure | oops i should have said oregon of course | 09:26 |
| MrClif | Yes I know of that one. | 09:26 |
| kanzure | http://brainsilo.org/ | 09:26 |
| kanzure | http://watershedpdx.com/ | 09:27 |
| kanzure | ok. | 09:27 |
| MrClif | are they all exactly the same or do people use different models? | 09:27 |
| kanzure | some people use different models | 09:27 |
| kanzure | http://hackerspaces.org/wiki/List_of_Hacker_Spaces | 09:27 |
| kanzure | some of them are their own entities (LLCs, 501c3s, etc.) | 09:27 |
| kanzure | others are franchises (TechShop).. which i guess isn't really the same thing precisely | 09:28 |
| kanzure | fablabs are via academic grants and are probably owned by universities (or something) | 09:28 |
| MrClif | i know there is one in portland havn't visited them yet. | 09:28 |
| kanzure | brainsilo and watershedpdx are both in portland | 09:29 |
| MrClif | there are two now, cool! | 09:29 |
| kanzure | there's also PSAS which does some crazy stuff that jrayhawk might attest to | 09:29 |
| kanzure | jrayhawk: are you even alive anymore | 09:29 |
| MrClif | so do people every try to bring in some small money makeing projects to keep the members busy if they are looking for something to do? | 09:30 |
| MrClif | eg you might crank out a few sets of reprap parts and sell them on ebay. | 09:31 |
| kanzure | yeah i'm pretty sure that happens often | 09:31 |
| kanzure | fenn wanted to sell reprap parts on ebay.. dunno what happened to that plan | 09:32 |
| MrClif | Nice... is that structured into the bylaws? | 09:32 |
| kanzure | each space has different bylaws (unless they copied them from somewhere) | 09:32 |
| kanzure | atx hackerspace copied a number of its bylaws from noisebridge iirc | 09:33 |
| MrClif | Maybe the market dropped out of reprap parts I've been trying to ascertain what they're going for these days. | 09:33 |
| MrClif | do you know of any good howtos on how to set up and structure hackerspaces? | 09:34 |
| jmil | MrClif: market is still strong check ebay | 09:36 |
| jmil | it will drop precipitously though now that ToM are in the wild | 09:36 |
| jmil | thing-o-matic from makerbot | 09:37 |
| MrClif | hmmm isn't ToM a web site? | 09:37 |
| MrClif | ah its a new makerbot hmmmm.... How does it compare to the Mendel? | 09:38 |
| kanzure | if anyone would retweet this i'd <3 you forever http://twitter.com/kanzure/statuses/15090547714695168 | 09:41 |
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| * dbolser puts in a claim for infiniate <3s | 09:45 | |
| kanzure | MrClif: lookup "hackerspace design patterns" | 09:55 |
| MrClif | ok thanks | 09:56 |
| kanzure | 1996 Light-directed synthesis of high-density oligonucleotide arrays using semiconductor photoresists http://ws1.izbi.uni-leipzig.de/pdf/mcga-96-93-13555-oligosynth.pdf | 09:56 |
| kanzure | hm.. | 09:57 |
| MrClif | I was just checking out thing-o-matic, I didn't find a vid yet of the eject process. | 09:57 |
| MrClif | are there people working on something liike that for reprap? | 09:57 |
| jmil | there's a printable one on thingiverse | 09:59 |
| MrClif | ok I'll check it out. | 10:00 |
| jmil | http://wiki.makerbot.com/abpv1 | 10:00 |
| jmil | has movies | 10:00 |
| MrClif | Thanks :-) | 10:01 |
| MrClif | It seems like the heated platform means you no longer have to build rafts. | 10:06 |
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| jrayhawk | no i am dead | 10:15 |
| jrayhawk | wooo i am a ghost | 10:15 |
| kanzure | do you go away if i spray you with garlic | 10:18 |
| MrClif | Hi Jrayhawk, can you give me a link to PSAS so I can check it out? | 10:28 |
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| jrayhawk | http://psas.pdx.edu/ | 10:41 |
| jrayhawk | http://psas.pdx.edu/news/2010-10-17-2/ being interesting | 10:42 |
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| kanzure | this is good: | 11:14 |
| kanzure | A short history of oligonucleotide synthesis | 11:14 |
| kanzure | http://www.trilinkbiotech.com/tech/oligo_history.pdf | 11:14 |
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| MrClif | Thanks jrayhawk, very interesting. | 12:08 |
| kanzure | "hey, so how hard do you think it would be to fab a, say 150 kw, electric motor?" | 12:14 |
| MrClif | How much steel and copper would that take? | 12:15 |
| archels | kanzure: Incidentally, I'm thinking of building a linear motor. | 12:15 |
| MrClif | usually the cases for big motors are cast no? | 12:16 |
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| kanzure | drew sez "there was a project to move to a two step peroxide based synthesis cycle ~2001-2003 involving people descended from the Boulder CO groups who had pioneered phosphoramidites." | 12:20 |
| kanzure | that's not very encouraging | 12:20 |
| kanzure | hrm. | 12:20 |
| kanzure | yo drew endy, you're supposed to be into dna synthesis | 12:20 |
| kanzure | hektor / wall-drawing alternative http://www.kickstarter.com/projects/notever/the-drawing-machine | 12:22 |
| kanzure | pics: http://web.me.com/sami6877/unanything/000/000.html | 12:25 |
| kanzure | memory enhancement via neuropeptide S http://www.eurekalert.org/pub_releases/2010-12/uoc--urf121410.php | 12:29 |
| kanzure | "Neuropeptide S Enhances Memory During the Consolidation Phase and Interacts with Noradrenergic Systems in the Brain" | 12:30 |
| kanzure | abstract: Neuropeptide S Enhances Memory During the Consolidation Phase and Interacts with Noradrenergic Systems in the Brain | 12:30 |
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| kanzure | i don't get it | 14:00 |
| kanzure | http://www.sloning.com/index.php?option=com_content&task=view&id=9&Itemid=32 | 14:00 |
| kanzure | it looks like DNA libraries + ligation | 14:00 |
| kanzure | except they don't use ssDNA | 14:01 |
| kanzure | but they claim it's not just a library plus ligation? | 14:01 |
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| kanzure | cool erik finished his thesis | 14:15 |
| kanzure | Thesis on the viability of open source development for the design of physical objects | 14:15 |
| kanzure | http://groups.google.com/group/openmanufacturing/browse_thread/thread/75a079b45bc8c649 | 14:15 |
| kanzure | intro to open source hardware http://blog.upverter.com/electronics/intro-to-open-source-hardware/ | 14:19 |
| kanzure | mobile sensing platform took the wrong domain name >:o http://openrtms.org/ | 14:19 |
| kanzure | funny: http://kevinw.github.com/2010/12/15/this-is-your-brain-on-vim/ | 14:24 |
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| kanzure | hi jrabbit | 14:59 |
| jrabbit | hi | 14:59 |
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| kanzure | hi thesnark | 15:39 |
| kanzure | hi QuantumG | 15:39 |
| thesnark | hey kanzure | 15:39 |
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| QuantumG | hey, kinda sick of my internet falling out | 15:40 |
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| kanzure | QuantumG: you should use a server and just connect to the server | 15:41 |
| QuantumG | kanzure: ever looked at metal spraying? | 15:41 |
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| QuantumG | http://www.metalspraysupplies.com/about/what-is-metal-spraying.htm | 15:42 |
| QuantumG | http://www.metalspraysupplies.com/applications.htm | 15:42 |
| QuantumG | for example | 15:42 |
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| kanzure | QuantumG: no | 15:44 |
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| QuantumG | was thinking of asking them if some reprap printed parts could be sprayed without heat deformation | 15:46 |
| kanzure | hi NAK | 16:05 |
| kanzure | QuantumG: why would you want to metal spray on top of reprap parts? | 16:08 |
| QuantumG | well, my interest is in making thin walled highly detailed metal parts | 16:10 |
| kanzure | isn't there some sort of foam casting that can do this too | 16:10 |
| QuantumG | reprap makes it fast/easy to make the high detail.. metal spraying to build up a layer looks like a cheap way to get high accuracy | 16:11 |
| QuantumG | casting is horrible accuracy | 16:11 |
| NAK | hi kanzure | 16:13 |
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| kanzure | oh oops.. for anyone following along at home the reference that drew endy gave turns out to be this: | 16:15 |
| kanzure | Solid-Phase Oligodeoxynucleotide Synthesis: A Two-Step Cycle Using Peroxy Anion Deprotection | 16:15 |
| kanzure | http://pubs.acs.org/doi/abs/10.1021/ja030376n | 16:15 |
| kanzure | more papers listed here: http://groups.google.com/group/diybio/browse_thread/thread/67ae072bd9d161a9 | 16:16 |
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| kanzure | http://www.kurzweilai.net/the-pace-and-proliferation-of-biological-technologies-2 | 17:49 |
| kanzure | "By 2010 a single person will be able to sequence or synthesize 10^10 bases a day." | 17:49 |
| kanzure | so it costs about $0.30 per bp at the moment to synthesize DNA | 17:50 |
| kanzure | that's about $3 billion dollars for 10^10 bp | 17:50 |
| kanzure | i should send an invoice to rob carlson | 17:50 |
| kanzure | care of ray kurzweil. | 17:50 |
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| delinquentme | rob carlson? | 17:54 |
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| kanzure | delinquentme: he's a bit of a dick in the synthetic biology community | 17:58 |
| kanzure | rips people off for lots of $$$ | 17:58 |
| delinquentme | principal @ biodesic? | 17:59 |
| kanzure | that just means he's a consultant | 17:59 |
| delinquentme | haha quite a title... who did he rip off recently | 18:00 |
| delinquentme | and is hes done this many time s? | 18:00 |
| kanzure | the lava amp guys | 18:00 |
| kanzure | they gave him $100k to build a prototype- they should have given him only $2k | 18:00 |
| delinquentme | lava lamp? | 18:04 |
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| kanzure | delinquentme: a weird thermocycler project that joseph jackson and guido took on | 18:09 |
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| jrayhawk | kurzweil and his cadre of exponential growth futurists seem to screw up biology predictions a lot more than compsci predictions | 18:39 |
| QuantumG | curvology | 18:41 |
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| jrayhawk | I wonder how much of that is due to onerous regulation in the field of medicine. | 18:51 |
| kanzure | wait, what's carlson's relationship to kurzweil? | 18:51 |
| kanzure | i thought they hated each other (or something) | 18:51 |
| kanzure | also, "a weight lifter almost never lifts weights in training" is news to me. from http://www.engin.brown.edu/courses/en123/Lectures/HillEqn.htm | 18:52 |
| delinquentme | yeah thats interesting | 18:55 |
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| kanzure | ouch, denied | 20:24 |
| kanzure | i asked my old molecular biology / synthetic biology professor about next-generation DNA synthesis | 20:24 |
| kanzure | he says: "We run our own DNA Fab, making ca. 100x 1 kb / week. I don't think there are any options for DIY, which is pretty much as it should be." | 20:24 |
| kanzure | i wasn't even talking about DIYable methods | 20:25 |
| kanzure | although he did blog negatively about diybio once or twice | 20:25 |
| NAK | dang | 20:46 |
| NAK | it | 20:46 |
| NAK | link to his blog? | 20:47 |
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| kanzure | NAK: http://ellingtonlab.org/blog/?p=104 | 20:48 |
| kanzure | NAK: http://ellingtonlab.org/blog/?p=153 | 20:48 |
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| kanzure | hm that's not so negative now that i look | 20:56 |
| kanzure | human augmentation http://ellingtonlab.org/blog/?p=49 | 21:06 |
| kanzure | i'm not really sure why transhumanists spontaneously gather around his lab | 21:06 |
| kanzure | videos from the agi 2010 conference http://vimeo.com/channels/agi10 | 21:07 |
| kanzure | (that was from march 2010) | 21:07 |
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| jmil | micromilling for lung engineering assist devices: http://pubs.rsc.org/en/Content/ArticleLanding/2011/LC/C0LC00158A | 21:33 |
| jmil | lemme know if you want the paper, pm me your email address | 21:34 |
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| kanzure | jmil: i do i do | 21:43 |
| jmil | sent | 21:44 |
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| joshcryer | http://www.youtube.com/watch?v=cuMzFNsvOVk | 22:37 |
| kanzure | git push origin master | 22:44 |
| kanzure | fatal: The remote end hung up unexpectedly | 22:44 |
| kanzure | jrayhawk: i blame you | 22:44 |
| NAK | hey, I liked the one one ingenuity | 22:44 |
| NAK | so far | 22:44 |
| NAK | that's the only one Ive read | 22:44 |
| kanzure | jrayhawk: shouldn't push work via git:// ? | 22:46 |
| mayko_ | so | 22:53 |
| mayko_ | protip | 22:53 |
| mayko_ | parafilm melts in a pressure cooker | 22:53 |
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| jrayhawk | that's rather odd | 23:38 |
| jrayhawk | try it with -v? | 23:38 |
| jrayhawk | oh no not via git:// | 23:38 |
| jrayhawk | I have no useful means of authenticating that | 23:38 |
| jrayhawk | I guess that's not strictly true; joeyh has a hook that determines if a push involves files that are supposed to be publicly editable anyway and refuses to update the ref otherwise | 23:39 |
| jrayhawk | Which I'm not really sure I like the concept of either. | 23:40 |
| --- Log closed Thu Dec 16 00:00:07 2010 | ||
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