| --- Log opened Fri Jul 29 00:00:01 2011 | ||
| archels | a cockroach was nibbling your toe. | 00:55 |
|---|---|---|
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| kanzure | archels: well, tell it to stop | 05:44 |
| foucist | cockroaches evolved with us | 05:44 |
| foucist | they're like dogs | 05:44 |
| foucist | co-evolution! | 05:44 |
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| kanzure | "Arnsten said that the aging prefrontal cortex appears to accumulate excessive | 06:34 |
| kanzure | levels of a signaling molecule called cAMP, which can open ion channels and | 06:34 |
| kanzure | weaken prefrontal neuronal firing. Agents that either inhibited cAMP or | 06:34 |
| kanzure | blocked cAMP-sensitive ion channels were able to restore more youthful firing | 06:34 |
| kanzure | patterns in the aged neurons. One of the compounds that enhanced neuronal | 06:34 |
| kanzure | firing was guanfacine, a medication that is already approved for treating | 06:34 |
| kanzure | hypertension in adults, and prefrontal deficits in children, suggesting that | 06:34 |
| kanzure | it may be helpful in the elderly as well." | 06:35 |
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| Lucas_ | http://www.nature.com/gt/journal/v18/n4/full/gt2010147a.html | 06:37 |
| Lucas_ | For Kanzure | 06:37 |
| kanzure | what is it | 06:37 |
| Lucas_ | Human Artificial Chromosome vectors for gene therapy | 06:42 |
| Lucas_ | quite yummy, if I do say so myself | 06:42 |
| Lucas_ | http://www.pnas.org/content/87/6/2211.full.pdf+html?sid=b3e80d13-02c4-437f-95f7-a9032aaacb2a "Site-specific integration by adeno-associated virus" | 06:56 |
| Lucas_ | "Rapid bacterial artificial chromosome modification for large-scale mouse transgenesis" http://www.nature.com/nprot/journal/v5/n10/full/nprot.2010.131.html | 06:59 |
| kanzure | weird, nature chemistry uses adobe indesign cs5 for formatting papers | 07:44 |
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| kanzure | oscon 2011 "garage biology and diybio" http://www.youtube.com/watch?v=42aPiIwRLf0 | 09:43 |
| kanzure | unfortunately it's eri gentry | 09:43 |
| kanzure | argh nobody cares about your life story | 09:45 |
| kanzure | http://assets.en.oreilly.com/1/event/61/Garage%20Biology%20And%20DIYbio_%20Because%20We%20Can,%20Because%20We%20Have%20To%20Presentation.pdf | 09:45 |
| fenn | i feel like i've been plunged into a bad translation of shadowrun | 09:46 |
| fenn | so why aren't they using the diy version | 09:47 |
| fenn | apparently schloendorn got funded and has a "real" lab now | 09:47 |
| kanzure | yes | 09:47 |
| kanzure | for a while now? since late 2009 or early 2010 i thought | 09:48 |
| fenn | yeah | 09:48 |
| kanzure | "the world is just not ready for people like us" oh god fuck this shit | 09:48 |
| kanzure | why am i even associated with this person | 09:48 |
| fenn | "1st meeting in new space" where is that? | 09:49 |
| kanzure | uh uh.. i know this one | 09:50 |
| kanzure | sunnyvale? | 09:50 |
| fenn | ugh | 09:50 |
| fenn | desolate car-infested wasteland | 09:50 |
| fenn | i went through a trial period there and promptly fled to foggy SF | 09:51 |
| fenn | but not before all my clothes faded in the sun | 09:51 |
| QuantumG | argh, the day star | 09:51 |
| fenn | srsly, that nuclear inferno is bad news | 09:51 |
| fenn | hide your wife, hide your kids | 09:52 |
| kanzure | ah at 13min 40sec she says it's sunnyvale | 09:52 |
| fenn | the problem with the south bay is it's boring as fuck, and boring people don't fiddle around with biotech in their spare time | 09:53 |
| fenn | <- bigot | 09:53 |
| fenn | anyway i'd love to be proven wrong | 09:53 |
| fenn | okay time to do some optics calculations | 09:54 |
| foucist | fenn: south bay = sf ? | 09:57 |
| fenn | south bay = sunnyvale, palo alto, mountain view | 09:57 |
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| kanzure | wow the python argument parser libs still suck | 11:21 |
| kanzure | i've always been a fan of optfunc (not optparse or argparse) | 11:21 |
| kanzure | just tried out "argh" | 11:21 |
| kanzure | argh makes you add a decorator (@arg) for each parameter to your function | 11:21 |
| kanzure | and then makes you use a single variable for your parameters | 11:21 |
| kanzure | optfunc at least has the decency to investigate the parameters of your function itself | 11:21 |
| kanzure | but neither of these do tab completion for bash | 11:21 |
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| kanzure | http://blogs.nature.com/news/2011/07/us_court_upholds_myriad_patent.html | 16:40 |
| kanzure | "he United States Court of Appeals for the Federal Circuit says patents on genes and even on the isolation of a specific gene are okay" | 16:40 |
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| uniqanomaly | has anyone patented composition of air yet? | 17:06 |
| uniqanomaly | "we are so sorry sir, you cannot exploit in your body air composed like that because we have patent for it" | 17:07 |
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| kanzure | more: http://www.patentlyo.com/patent/2011/07/federal-circuit-isolated-human-dna-molecules-are-patentable.html | 17:59 |
| QuantumG | and once again.. would you prefer they kept their results secret? | 18:05 |
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| QuantumG | .. whenever you're ready to have a grownup conversation about patents. | 18:20 |
| kanzure | their results about brca1? they didn't do that | 18:22 |
| uniqanomaly | QuantumG: wanna grownup conversation about patents | 18:27 |
| uniqanomaly | http://en.wikipedia.org/wiki/The_Wright_brothers_patent_war | 18:27 |
| uniqanomaly | explain this | 18:27 |
| uniqanomaly | "In 1906 the Wrights received a patent for their method of flight control and fiercely defended it in the years afterward, suing foreign and domestic aviators and companies, especially Glenn Curtiss, in an attempt to collect licensing fees. The legal threat suppressed development of the U.S. aviation industry." | 18:27 |
| QuantumG | yes, they were douchebags | 18:28 |
| QuantumG | I've made the argument against the Wrights dozens of times. | 18:28 |
| uniqanomaly | are you kidding me | 18:28 |
| QuantumG | no.. why? | 18:29 |
| uniqanomaly | suppressing development is the outcome of patents | 18:29 |
| QuantumG | is this your grownup argument? | 18:29 |
| uniqanomaly | don't rationalize that by saying Wrights were douchebags | 18:29 |
| QuantumG | what about trade secrets.. do they suppress development? | 18:29 |
| uniqanomaly | why you change subject to trade secrets? | 18:30 |
| QuantumG | which do you want? secrecy or a functioning patent system? you can't have it both ways.. | 18:30 |
| QuantumG | if your answer is that you want neither then you're not having a grownup conversation. | 18:30 |
| uniqanomaly | of course, there is no secrecy right now, everyone makes everything public by patent system | 18:32 |
| QuantumG | you just can't have a grownup argument can you? | 18:33 |
| QuantumG | "all patents are bad" is just ignorance | 18:33 |
| QuantumG | similarly for all trade secrets. | 18:34 |
| QuantumG | it's almost a zero-sum between the two to get the maximum benefits | 18:34 |
| uniqanomaly | of course if you are explaining suppressed development of whole industry by someone being a douchebag, I just can't argue with you | 18:35 |
| QuantumG | but hey, go back to living in your little black and white world.. it'll maximize your feelings of moral superiority. Buy a Mac while you're out. | 18:35 |
| uniqanomaly | I have nothing left to say to you | 18:36 |
| QuantumG | that's cause you're a fucking child | 18:36 |
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| kanzure | glow in the dark dogs in korea http://www.dreamdogs.co.uk/glow-in-the-dark-dogs-cloned-by-scientists-1166.html | 22:34 |
| --- Log closed Sat Jul 30 00:00:03 2011 | ||
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