2011-11-10.log

--- Log opened Thu Nov 10 00:00:35 2011
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eudoxiahey, everybody. the Roadmap says this: "* Where is the old grass-roots open source group that was researching worm mind-uploading?02:50
eudoxia"02:50
eudoxiaand i think the answer to the question is http://groups.google.com/group/openworm02:50
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kanzureeudoxia: nope, it was actually called MURG06:57
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kanzurehttp://hardware.slashdot.org/story/11/11/10/1353240/shanghai-government-proposes-100-community-hackerspaces07:17
JayDuggerHey, kanzure.07:23
JayDuggerThank you for your help yesterday.07:24
JayDuggerTurns out the position with Objet requires "up to 80%​ travel".07:25
kanzurethat sounds fun07:25
kanzurewhat's the position?07:25
JayDuggerThe word I have in mind lacks an "n," but it starts with "f" and "u" in that order.07:25
JayDuggerThey've a similar position in Indianapolis, IN.07:26
kanzurewhat's the position?07:26
JayDuggerhttp://jobview.monster.com/Field-Service-Engineer-Job-Indianapolis-IN-US-103207079.aspx07:26
kanzurefield service engineer? o.O07:26
JayDuggerIf that link fails, I'll email it to you or paste it.07:26
JayDuggerYeah...basically what I did for my former employer. Not bad, but very hard on marriages.07:27
kanzureare you unemployed?07:27
JayDuggerNo.07:27
JayDuggerIf I was, that'd be different.07:27
JayDuggerDepending on their salary offer, it might mean a big pay cut.07:28
kanzurehttp://boingboing.net/2011/11/09/library-builds-a-hackerspace.html07:28
JayDuggerGood for that library!07:29
JayDuggerThe first thing they make should be a cell phone jammer.07:29
JayDuggerWow...and half-way intelligent comments on BB.07:32
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kanzurethe libraryspace should build a book scanner bot07:46
kanzureit will ride around on the shelves, pull a book and scan it07:46
JayDuggerRight after the cell phone jammer, yes.07:46
kanzurethen it will incinerate the book with lasers07:46
JayDuggerHa-ha!07:46
JayDuggerLasers are good, flamethrowers are better!07:47
JayDugger(You don't have to wear safety goggles with flamethrowers.)07:47
JayDuggerAnd another robot that goes up to random patrons and says "Sh!"07:48
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Utopiahhttp://hardware.slashdot.org/story/11/11/10/1353240/shanghai-government-proposes-100-community-hackerspaces08:26
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falmot_http://ansistego.sf.net/ansi-mods.tgz08:59
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kanzurewhat is thingdoc15:56
kanzurehttps://github.com/prusajr/ThingDoc15:57
kanzurehrmm15:57
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delinquentmeso of these disciplines: structural biology, biotechnology, cell biology, bioinformatics and systems biology18:39
delinquentmewhich would the brains here regard as the best route to human life extension18:39
kanzureo_O why are you categorizing things like this18:40
kanzurethe best route is asskicking18:40
kanzureimmortality or bust!18:40
delinquentmelol18:41
delinquentmethat .. is18:41
delinquentmeapparent?18:41
delinquentmelolol18:41
klafkathe best route is not going to be methodological but paradigmatic18:50
klafkaactually the 'best route' is going to be physics and industrial manufacturing really18:51
klafkaIMO18:51
epitrondelinquentme: a biological system is an integrated whole -- those are just knowledge divisions to make it easier for people to specialize... they're all important to life extension18:52
klafkabiology needs transformational hardware which will drive the ability to cheaply and quickly answer biological questions18:52
epitronyep18:52
epitronin other words, biotechnology -> bioinformatics -> cell biology & systems biology18:52
epitronwhich feed back into bioinformatics18:52
klafkafor instance, a way to real time understand protein movement in cells, protein quantities in cells and fuck while we're wishing protein/RNA conformational states in cells18:53
klafkaon a mass scale18:53
klafkaanother thing obviously would be a way to effectively and cheaply write DNA18:54
epitronyou know whats good at writing DNA?18:54
epitroncells!18:54
klafkaheh18:54
epitronwe should hack bacteria to respond to print DNA like tickertape in response to flashing lights18:54
epitronvia rhodopsin implanted in the cell wall18:54
klafkalike the 'camera bacteria'18:55
epitronwhat's that?18:55
epitronnevermind, i googled :)18:55
klafkathere were some GE bacteria that basically acted like a camera, expose them to an image18:55
klafkaright18:56
epitronthat's kinda neat18:56
delinquentmewas an iGem project18:56
epitronsounds pretty simple18:56
delinquentmeso PROGRAMING is part of it18:56
delinquentmebc machine efficiency is a huge part of it18:56
joshcryerbio is too hard for me to grasp :(18:57
epitronprogramming what to make what machine efficient?18:57
delinquentmethe conceptual aspect is huge for someone to actually be able to bound through and mess with the comcepts of it18:57
epitronjoshcryer: not with THAT attitude!18:57
delinquentmeepitron, programming not only in applications of running shit like liquid handling18:57
delinquentmebut also in bioinformatics and even simple data processing18:58
epitronprogramming the cell?18:58
delinquentmethat'd be hot.18:58
delinquentme:D18:58
joshcryerepitron, it's equivalent to alchemy, to me.18:58
delinquentmeright now the bio if fucking black magic to me18:58
delinquentmeehhh well18:58
delinquentmenot black magic18:58
joshcryerI saw that thing about the imaging bacteria, I think it was an ecoli strain.18:58
delinquentmeprobs18:58
joshcryerThey didn't explain how they did it to any usable detail, that I saw (I didn't read any papers, if any were released, midn you).18:59
delinquentmeyeast is another good model organism to play with joshcryer18:59
delinquentmejoshcryer, more interesting is how to vector in proteins into differentiated cells in order to IPP them18:59
epitron<delinquentme> epitron, programming not only in applications of running shit like liquid handling18:59
epitroni still don't know what you're talking about :)18:59
delinquentmemaking pictures with bacteria is novel but... there are more useful things19:00
delinquentmeepitron, so im a programmer turned sane19:00
delinquentmethus im like " how can i save my ass asap "19:00
epitronare you talking about programming software?19:00
epitronmicrofluidic control systems?19:01
delinquentmeand so im outlining all the different diciplines involved with pushing life extension19:01
joshcryerdelinquentme, I was amused to learn that proteins can be separated from cells with a household detergent, then you layer on new cells that you've grown in a lab, and volia, you have a working organ or whatever with no immunosuppresant need.19:01
delinquentmeepitron, thats just what ive worked on19:01
epitronoutlining? more like scribbling in crayon19:01
delinquentmeepitron, ha19:01
delinquentmeso im saying that ... these are all the things which are worthwhile19:02
delinquentmejoshcryer, im not sure it was as simple as house hold detergent?19:02
joshcryerAI IS THE FUTURE19:02
delinquentmeAI is part of it19:02
joshcryerdelinquentme, http://en.wikipedia.org/wiki/Protein_purification (sodium dodecyl sulfate)19:03
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joshcryerI saw an episode of NOVA that discussed how they discovered it.19:03
joshcryerThey literally just brute forced it until they figured it out.19:03
delinquentmeyou got a link for that?19:04
epitronyeah, that sounds good :)19:04
joshcryerEh, it's been awhile, sorry. It was in the last 6 months to a year.19:04
joshcryerLet me look then. :)19:04
epitrondanke!19:04
delinquentmeso i know we've stripped tracheas19:06
delinquentmespelling? ^19:06
delinquentmebut i wasnt so sure about the process of stripping away the foreign material19:06
delinquentmebut rebuilding on the scaffolding sounds simple enough19:07
joshcryerAhh.19:07
delinquentmeput cells on stuff .. incubate stuff19:07
joshcryerIt wasn't NOVA, it was NOVA ScienceNow: http://www.pbs.org/wgbh/nova/body/can-we-live-forever.html19:07
delinquentmejoshcryer, you do know about organovo right? http://www.organovo.com/products/novogen-mmx-bioprinter19:07
joshcryerdelinquentme, the impression I got was that it works with all organs, they have hearts and lungs working so far, but nothing precludes it from working with all of them, as far as I understood.19:07
delinquentmeO_O;19:08
delinquentmewas this a human organ?19:08
delinquentmedont they swap in pig hearts?19:08
delinquentmeim wanting to say thats been done before .. but the same immuno suppressant stuff is involved19:09
joshcryeryes for the protein shell, but it's human cells for the structure19:09
joshcryerThey're working on cloning the protein shell.19:09
joshcryerI am so tired of the low info content of shows these days. That whole 13 minute clip the relevant part is about 2 minutes. :(19:11
delinquentmehaha19:11
delinquentmeid fucking LOVE more sci education19:11
joshcryer6m40s is where they start explaining the protein framework of organs.19:12
delinquentmeJESUS ITS BEUAUTIFULLLLLLLLLLLLLLLLLLLLLLLLLLLLLLL19:13
delinquentmeLUNGS19:13
delinquentmeGROWN19:13
joshcryer(the other stuff is just the dated ears on mice stuff)19:13
delinquentmeGOD DAMN HELL YES>19:13
joshcryerYeah, it's 5-10 years out, max19:13
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joshcryer(and heart disease will be effectively cured, though expensively)19:17
delinquentmemy problem might be the fact that I want to do it all19:19
joshcryerThat is definitely a problem.19:20
delinquentmemachine learning observing bio simulations run in silico to then govern what should we break out into actual cell and chemical trials19:21
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delinquentmewhats up with the ear on the mouse19:26
delinquentmewouldnt the mouse have immuno issues?19:27
delinquentmecommonly found in shampoo19:30
delinquentmeSTFU19:30
joshcryerthe ear mouse thing is so old19:31
joshcryerthis whole stripping organs of cells thing and preserving the protein structure is awesome19:32
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