| --- Log opened Sun May 13 00:00:09 2012 | ||
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| eudoxia | so the CI site was redesigned | 07:32 |
|---|---|---|
| eudoxia | it looks a lot less late nineties now | 07:33 |
| ENKI-][ | is that supposed to be a good thing? | 07:41 |
| eudoxia | I suppose | 07:41 |
| ENKI-][ | a site that looks like it was made in 1997 isn't wasteful like a site that looks like it was made in 2007 is. | 07:42 |
| eudoxia | why wasteful? | 07:45 |
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| @kanzure | day 7 of gmail backup | 09:26 |
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| klafka1 | gmail backup? | 10:27 |
| @kanzure | klafka1: just backing up my email with offlineimap | 10:34 |
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| klafka1 | perfect berry rockstar is the best rockstar | 11:30 |
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| klafka1 | argh does someone have familiarity with matplotlib ? i think i'm doing something dumb | 11:54 |
| @kanzure | i've used it in the past, but not recently | 11:56 |
| @kanzure | what's up? | 11:56 |
| klafka1 | either it is acting funky or my MCMC sampler is acting funky | 11:57 |
| klafka1 | not sure | 11:57 |
| klafka1 | i think i'm just going to implement this for discrete distributions and test it that way | 11:57 |
| klafka1 | sooo much easier to test MCMC with discrete distributions | 11:57 |
| klafka1 | also i'm not sure if this i correct but holy crap creating a hist from 10,000 data points is taking up 2gb of memory | 11:58 |
| klafka1 | that's insane | 11:59 |
| @kanzure | hist = histogram? | 11:59 |
| klafka1 | yeah | 12:07 |
| klafka1 | something was weird there | 12:07 |
| klafka1 | it was going at 5gb when i killed it | 12:07 |
| @kanzure | well, pastebin what you've got and i'll stare at it | 12:10 |
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| @kanzure | i am disappointed by the lack of information on the intertubes about properly re-slinking a slinky | 12:20 |
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| chevbird | happy mothers day | 13:12 |
| ThomasEgi | kanzure, a histoframm from 10k datapoints should fit into 32k float values. | 13:13 |
| @kanzure | ThomasEgi: for sure | 13:14 |
| ThomasEgi | at leas. if you fourier transform with 16k input | 13:14 |
| ThomasEgi | so how comes it takes so much memory? | 13:14 |
| ThomasEgi | oh.. it appears i meant klafka1 instead of you | 13:14 |
| ThomasEgi | silly autocomplete | 13:14 |
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| klafka1 | thomas yeah something is weird with it | 13:32 |
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| Mariu | later everyone | 15:41 |
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| * n_bentha is going ape-shit | 17:44 | |
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| n_bentha | that little bastard | 17:51 |
| n_bentha | he swore up and down that bglii had a cut site and that he could use bamhi instead of mfei | 17:51 |
| n_bentha | i'll kill him! | 17:51 |
| n_bentha | (there's no cut site for bglii for that fragment) | 17:58 |
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| @kanzure | n_bentha: awesome | 18:28 |
| n_bentha | :( | 18:29 |
| yashgaroth | well at least it's presumably free labor | 18:31 |
| n_bentha | ... | 18:33 |
| n_bentha | yea but still. such a waste of time and money eventhough it's 'free' | 18:34 |
| @kanzure | "For e[Cvery one mistake you make, we will add one additional year of grad school" | 18:34 |
| n_bentha | hehe | 18:35 |
| yashgaroth | I'm starting to reconsider grad school at this point | 18:36 |
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| @kanzure | yashgaroth: did you get rejected | 18:38 |
| yashgaroth | no response, which is seemingly so | 18:38 |
| yashgaroth | lilly has another purification job opening soon, according to a director | 18:38 |
| yashgaroth | but it's all either "oh this is a cloning job and you don't have a lot of professional time with that even though it's shit-easy" | 18:39 |
| @kanzure | yashgaroth: you could also identify an opportunity and do a company, | 18:39 |
| yashgaroth | or "ah you have purification experience, can you do [biochemical engineering]" | 18:39 |
| yashgaroth | one does not simply do a company | 18:39 |
| yashgaroth | all of the legal and profitable stuff is patented | 18:40 |
| n_bentha | yashgaroth: i thought u were working? | 18:40 |
| yashgaroth | was until late march, 2/3 of company got laid off :/ | 18:40 |
| @kanzure | n_bentha: his employer collapsed | 18:40 |
| n_bentha | 0_o | 18:40 |
| n_bentha | like as in fell over? | 18:41 |
| n_bentha | or the company tanked? | 18:41 |
| yashgaroth | the board decided not to continue funding due to lack of progress | 18:41 |
| yashgaroth | it was supposed to be an alternative scaffold to antibodies, but "antibodies are doing a lot of new stuff these days so fuck it you're fired" basically | 18:41 |
| yashgaroth | half-life, solubility and expression were all far lower than antibodies, so it was mostly to get around IP stuff | 18:42 |
| yashgaroth | not that I'm bitter about the platform, but | 18:44 |
| @kanzure | yashgaroth: so what's your plan ? | 18:44 |
| yashgaroth | keep applying to the few jobs open here, maybe move to SF | 18:44 |
| n_bentha | ah ok. hope you find something soon | 18:47 |
| yashgaroth | I haven't been looking a whole lot, and diablo 3 coming out on tuesday shan't help matters I fear | 18:47 |
| chevbird | where's here? | 18:53 |
| yashgaroth | san diego | 18:53 |
| @kanzure | chevbird: san diego | 18:54 |
| @kanzure | damn you irc lag | 18:54 |
| yashgaroth | mwahaha | 18:54 |
| @kanzure | yashgaroth: you went from "independent consultant" to "research associate"? sounds like a downgrade | 18:55 |
| chevbird | boston's pretty exciting biotech-wise lately if youre interested in leaving | 18:55 |
| yashgaroth | nah that's their default position name for 'contractor' | 18:56 |
| yashgaroth | nah I'm staying west coast | 18:56 |
| @kanzure | yashgaroth: contractor sounds better than 'associate' but whoknows | 18:56 |
| yashgaroth | it ain't, it's just another term for temp | 18:56 |
| @kanzure | well definitely never write 'temp' on your resume | 18:56 |
| yashgaroth | but yeah their standard was to hire all scientists on like that for the first 1-2 years | 18:57 |
| chevbird | yikes | 18:57 |
| chevbird | sounds like a runaround | 18:58 |
| yashgaroth | it's so if you're shit they can fire you without dealing with those pesky employment laws | 18:58 |
| @kanzure | one minor criticism about your resume.. you might want to consider a one-line statement or description for what your ideal role is | 18:58 |
| yashgaroth | yeah I've been slyly tailoring it to whatever the job posting says | 18:58 |
| @kanzure | i know "lab technician" doesn't sound ideal, but i can't think of a better description of what you did | 18:59 |
| yashgaroth | research associate is the default for someone with a bachelor's, unless the company calls everyone scientists | 18:59 |
| yashgaroth | though the terms are interchangeable | 18:59 |
| chevbird | i lump associate scientist in there too | 18:59 |
| @kanzure | ParahSailin has been following some bioinformatics leads, but it sounds like you would be happer with tissue and molecular work | 19:00 |
| @kanzure | *happier | 19:00 |
| ParahSailin | im employed :) | 19:00 |
| * yashgaroth shakes fist | 19:00 | |
| @kanzure | you took the houston job? | 19:00 |
| ParahSailin | i switched from wetlab to in silico | 19:00 |
| ParahSailin | yes | 19:00 |
| yashgaroth | how much programming knowledge do/did you need? | 19:01 |
| ParahSailin | wet lab is so cartelized it's ridiculous to want to get in there | 19:01 |
| yashgaroth | blergh yeah | 19:01 |
| @kanzure | yashgaroth: you shouldn't worry about programming knowledge; if you want to work on it, let me know and i can help you out | 19:01 |
| chevbird | cartelized meaning? | 19:01 |
| ParahSailin | i had no credentials, only the knowledge of data structures and general math skills that i brought to interview | 19:01 |
| yashgaroth | hey sure as long as it's work | 19:02 |
| ParahSailin | cartelized as in the instruments and equipment and all the reagents cost so much because of patents | 19:02 |
| @kanzure | yashgaroth: i could probably get you to the point of getting a comfortable SF/SV programming job (but getting a bioinformatis gig i'm not so sure about; i'm sure it's possible, but i'm not presently optimized for that) | 19:02 |
| ParahSailin | that big corps are the only game in town | 19:02 |
| ParahSailin | or guys that have enough vc to buy those | 19:02 |
| yashgaroth | well if it's not bio-related I don't know what I'd be doing there | 19:02 |
| ParahSailin | and they are going to restrict access to that as much as they can | 19:02 |
| @kanzure | yashgaroth: the way i suggest people do it is to make a demo product- usually a web app or mobile app- with a few weeks of your time, then parrot that around on your resume to land a junior programming gig | 19:03 |
| @kanzure | yashgaroth: right.. | 19:03 |
| ParahSailin | my bioinformatics job is scripting next gen sequencing data parsing | 19:03 |
| chevbird | ParahSailin: most are | 19:03 |
| @kanzure | ParahSailin: also.. for lab work, i thikn there's an endless supply of cheap labor.. scienceeexchange isn't helping that, because there's tons of poor labs that would love to take on low-cost labor/work | 19:03 |
| @kanzure | *think | 19:03 |
| ParahSailin | the only difference between the PI/CTO in wet lab and the monkey at the bench is that the PI managed to convince someone with money to let him use that equipment | 19:04 |
| ParahSailin | typically thats done through credentials or dicksucking | 19:04 |
| ParahSailin | thats a killer barrier to entry, not worth attempting to assault in this day of permanent recession | 19:05 |
| ParahSailin | thats why i sought out anything computer | 19:06 |
| ParahSailin | because a terminal and a desk is negligible capital cost to risk | 19:07 |
| yashgaroth | it's not like I mind benchwork, but after 12 hours of doing ELISAs, any amount of computer work seems blissful | 19:07 |
| chevbird | if you guys are interested in the critique-the-resume game i'd love some input on mine doiop.com/chevrette | 19:08 |
| @kanzure | chevbird: sure thing | 19:08 |
| @kanzure | chevbird: ah shit, another biologist :) | 19:09 |
| @kanzure | what brings you here? | 19:09 |
| ParahSailin | i imagine my employer is not too unique | 19:09 |
| chevbird | kanzure: i dont really know | 19:09 |
| @kanzure | chevbird: just wondering how you know about ##hplusroadmap | 19:09 |
| ParahSailin | any nextgen sequencing company is gonna need guys who can script basic parsing and assembly tasks and code some larger research projects | 19:09 |
| @kanzure | chevbird: what sort of emulsions and automation have you done work on? | 19:10 |
| chevbird | emulsion wise, basically illumina LC and specialty illumina LC (jumps, translocation detection, etc) | 19:10 |
| chevbird | for automation just about everything we do needs to end up on a liquid handler for atscale production | 19:11 |
| chevbird | so lots of different things | 19:11 |
| @kanzure | chevbird: two main criticisms of your resume; the coursework will probably have to go eventually, and second, your "COMPUTER AND LAB SKILLS" is nice and all, but there's too much space in between the left and right columns, plus not enough space between each row | 19:11 |
| chevbird | i keep hearing that about the coursework | 19:12 |
| @kanzure | i think it's fine at the moment, but in 5 or 10 years, probably not so much | 19:13 |
| chevbird | yea | 19:13 |
| @kanzure | what does LRIG do | 19:13 |
| @kanzure | i have a strong interest in lab automation and open source lab equipment, so i dunno if LRIG is up to anything worthwhile? | 19:13 |
| yashgaroth | two copyedit ones since I like to do that; "Broad Institue", and "production throughout by 400% through..." did you mean throughput, and also consider a synonym for through | 19:14 |
| chevbird | its a bunch of guys that get together for free food and chatting about new vendors and tech and etc | 19:14 |
| chevbird | usually over beer | 19:14 |
| @kanzure | ok cool | 19:14 |
| @kanzure | do any of them build lab automation tools? | 19:14 |
| @kanzure | or do they just buy things | 19:14 |
| chevbird | haha | 19:14 |
| chevbird | ok | 19:14 |
| chevbird | basically buying | 19:16 |
| @kanzure | okay neato | 19:17 |
| @kanzure | there's a regular around here that is building an open source liquid handling machine | 19:17 |
| @kanzure | and he doesn't know any potential customers | 19:17 |
| chevbird | death to agilent | 19:18 |
| @kanzure | chevbird: have you seen http://search.cpan.org/~jcline/Robotics-0.21/lib/Robotics/Tecan.pm | 19:19 |
| chevbird | kanzure: i have not | 19:20 |
| chevbird | looks awesome | 19:21 |
| @kanzure | chevbird: one of the projects in here is a microfluidic dna synthesizer, and we're hoping to do water-in-oil emulsions eventually with it | 19:24 |
| @kanzure | so that's why i was curious about your emulsion experience | 19:24 |
| chevbird | working on something very similar | 19:25 |
| chevbird | and hopefully i get a call back on a job from gnubio, whos whole company is built around that | 19:25 |
| @kanzure | i've heard of gnubio | 19:25 |
| @kanzure | i hate them for calling themselves gnu anything and not being open source, but whatever | 19:25 |
| @kanzure | no copyright/trademark on the animal i guess | 19:26 |
| chevbird | http://www.masshightech.com/stories/2010/05/31/daily32-GnuBio-launches-as-open-source-genome-sequencing-startup.html | 19:26 |
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| @kanzure | nono i said synthesis, not sequencing | 19:26 |
| chevbird | ok fine | 19:27 |
| chevbird | haha | 19:27 |
| @kanzure | but also: i haven't seen any of gnubio's "open source" stuff on the web; have i missed something | 19:27 |
| @kanzure | maybe i just suck at interneting | 19:27 |
| chevbird | they dont have much done yet | 19:27 |
| chevbird | which is why theyre expanding now | 19:27 |
| chevbird | to make good on the promise | 19:27 |
| @kanzure | i see. do they have money? | 19:28 |
| chevbird | id imagine so | 19:28 |
| chevbird | theyre expanding pretty agressively | 19:29 |
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| chevbird | hopefully so agressively that they call me back | 19:32 |
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| n_bentha | So who else is excited for the spacex launch (if it ever happens)? | 19:45 |
| n_bentha | May 19th | 19:46 |
| chevbird | yes | 19:46 |
| ParahSailin | i wish the american regime would have given me a couple million to start a space company rather than giving it to elon musk | 19:47 |
| yashgaroth | his pillows needed to be stuffed with $100 bills, to match his mattress | 19:47 |
| ParahSailin | nasa provided over half the capital in spacex without taking any equity | 19:49 |
| n_bentha | do they have 51%+ of the company's stock? | 19:50 |
| ParahSailin | without taking any equity | 19:50 |
| ParahSailin | no, it was just a free money grant | 19:51 |
| n_bentha | so stupid | 19:57 |
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| ParahSailin | but its private space flight | 20:14 |
| ParahSailin | free market enterprise is progress | 20:14 |
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| joshcryer | NASA's funding to SpaceX is predicated on delivery. | 21:09 |
| joshcryer | ie, SpaceX doesn't get paid unless they deliver. | 21:09 |
| joshcryer | This is in contrast to other companies like the ULA Alliance who got paid to do stuff that they didn't even have to deliver. (See the Ares I-X debacle.) | 21:10 |
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| Mokbortolan_ | http://chzscience.files.wordpress.com/2011/11/funny-science-news-experiments-memes-tongue-twister-spider-silk-spigots.jpg\ | 21:43 |
| n_bentha | 404 — File not found. | 21:43 |
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| @kanzure | n_bentha: probably because of the slash at the end | 21:49 |
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| n_bentha | thanks kanzure | 21:51 |
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| joshcryer | SIGGRAPH 2012 papers are fucking shit up. | 22:05 |
| @kanzure | joshcryer: in the bad way? | 22:05 |
| joshcryer | In a really sweet way. | 22:06 |
| joshcryer | http://kesen.realtimerendering.com/sig2012.html | 22:06 |
| joshcryer | this one is really cool: http://www.cemyuksel.com/research/stitchmeshes/ | 22:08 |
| joshcryer | afk | 22:08 |
| @kanzure | "I think for most startups with good performance metrics, expecting 1/5 of your pitches to convert is a good benchmark." | 22:10 |
| @kanzure | yikes.. 20%? | 22:10 |
| @kanzure | was from http://news.ycombinator.com/item?id=3969252 | 22:10 |
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| ParahSailin | wayland is something that is supposedly gonna replace x11? | 22:25 |
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| --- Log closed Mon May 14 00:00:09 2012 | ||
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