| --- Log opened Fri Jun 29 00:00:54 2012 | ||
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| @kanzure | "Fun fact: the word "ewok" is never once uttered or written in Return of the Jedi. We only know what they are called due to marketing and advertising, and other spin-offs involving them." | 00:29 |
|---|---|---|
| @kanzure | "we touch his arm, and we feel a shock, but our voltmeter shows nothing. he says it is chi." http://www.youtube.com/watch?v=3F3ovb2kZ9Q haha | 00:29 |
| @kanzure | i wonder if they would have believed him if he wasn't asian | 00:31 |
| chido | are there any memory-boosting drugs I could get without getting arrested? | 00:38 |
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| chido | ~> | 00:55 |
| augur | is there any work on self-assembly that's easy to get into? | 00:56 |
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| Tukotih | chido: For memory boosting drugs, see ##reddit-nootropics | 01:46 |
| Tukotih | #reddit-nootropics* | 01:46 |
| Tukotih | But the currently most popular one (which I love) is Noopept, check it out if you are interested. | 01:46 |
| Tukotih | I've taken it daily for a few months now with amazing results | 01:47 |
| chido | thanks | 02:09 |
| chido | can I just walk in a pharmacy and ask for it? | 02:10 |
| chido | ah well, I'll read into it a bit first | 02:10 |
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| Tukotih | Nope, but you can buy it from Ebay | 03:50 |
| Tukotih | And in bulk from cerebralhealth (I bought 10g there for a decent price) | 03:50 |
| Tukotih | If you have any questions ask them in #reddit-nootropics | 03:50 |
| Tukotih | chido: (Notice) | 03:51 |
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| archels | kanzure: What should I think of the "ZeroState Movement"? | 05:49 |
| archels | I just got an email to attend some polical activist brainstorming session http://cdfp.org/ | 05:49 |
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| @kanzure | archels: it seems to be some political thing and not doing much.. i say ignore it | 07:17 |
| @kanzure | chido: http://www.longecity.org/forum/topic/36691-ten-months-of-research-condensed-a-total-newbies-guide-to-nootropics/ | 07:18 |
| klafka | hey kanzure | 07:23 |
| @kanzure | hi klafka. | 07:27 |
| @kanzure | "Optogenetic stimulation of a hippocampal engram activates fear memory recall." http://www.ncbi.nlm.nih.gov/pubmed/22441246 | 07:35 |
| @kanzure | "A specific memory is thought to be encoded by a sparse population of neurons. These neurons can be tagged during learning for subsequent identification and manipulation. Moreover, their ablation or inactivation results in reduced memory expression, suggesting their necessity in mnemonic processes. However, the question of sufficiency remains: it is unclear whether it is possible to elicit the behavioural output of a specific memory by directly act | 07:35 |
| @kanzure | "Here we show in mice that optogenetic reactivation of hippocampal neurons activated during fear conditioning is sufficient to induce freezing behaviour. We labelled a population of hippocampal dentate gyrus neurons activated during fear learning with channelrhodopsin-2 (ChR2) and later optically reactivated these neurons in a different context. The mice showed increased freezing only upon light stimulation, indicating light-induced fear memory rec | 07:36 |
| @kanzure | hrmm i'm not sure a freezing behavior is diretly attributable to an engram | 07:36 |
| klafka | wpah | 07:36 |
| klafka | Center for Neural Circuit Genetics at the Picower Institute for Learning and Memory | 07:36 |
| @kanzure | no no it's longer than that | 07:36 |
| @kanzure | "Center for Neural Circuit Genetics at the Picower Institute for Learning and Memory, Department of Biology and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology" | 07:36 |
| @kanzure | oh they were listing the departments. oh well. | 07:37 |
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| klafka | kanzure I think that freezing is used in that model organism as an engram | 07:37 |
| klafka | although i agree | 07:37 |
| klafka | not directly relatable | 07:37 |
| superkuh | 1http://superkuh.com/library/Neuroscience/Hippocampal%20Formation/Optogenetic%20stimulation%20of%20a%20hippocampal%20engram%20activates%20fear%20memory%20recall_%20Nature_%202012.pdf | 07:38 |
| superkuh | Oh. Without the 1, obviously. | 07:38 |
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| archels | kanzure: Yes, it's kind of obvious that if you had an engram distributed among interconnected nodes, activating one of those nodes would spread activation to the other nodes, "recalling" the engram. | 07:39 |
| @kanzure | archels: that's hardly obvious. | 07:39 |
| @kanzure | why would a memory be encoding in a firing pattern, rather than the topology? | 07:40 |
| @kanzure | klafka: right.. it could just be that your optogenetic trigger just breaks enough shit and causes freezing | 07:41 |
| JayDugger | Good morning, everyone. | 07:52 |
| JayDugger | Anyone here ever use Prolog? | 07:52 |
| archels | kanzure: Memories are encoded in the structural synaptic connectivity pattern, so a particular group of neurons will be connected such that activating one or a few will activate the others. | 07:55 |
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| @kanzure | "Bone-eating marine worms use acid to feed on the skeletons of fish and whales" | 08:34 |
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| @kanzure | hi rmcl | 08:47 |
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| Mokbortolan_ | eww | 09:07 |
| Mokbortolan_ | you know what I can't wait for? | 09:08 |
| Mokbortolan_ | when the methane hydrate deposits thaw at the same time as the siberian peat bogs | 09:08 |
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| nmz787 | Mokbortolan_: that sounds gross | 09:23 |
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| chido | I'm setting up a DIYbio lab and putting together a list of basic equipment, what kind of fridge should I get? Like, what sort of specifications should I take into account? (how cool do I need it to be?) | 10:03 |
| @kanzure | you at least need a regular fridge (like from a regular kitchen) | 10:05 |
| @kanzure | a -80C freezer is really super useful | 10:05 |
| @kanzure | if you find one cheap, you should gnab it. | 10:06 |
| chido | I'm not sure a freezer would fit into a 2x3 m^2 space, but I can worry about that once I stumble over a cheap one :) | 10:08 |
| chido | so a regular kitchen fridge is enough? | 10:09 |
| @kanzure | i think you need to store dNTPs at -20C | 10:11 |
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| nmz787 | you don't want a "frost free" fridge/freezer, as they cycle to reduce ice buildup | 10:38 |
| nmz787 | if you can only get a frost free, then you need to store your stuff in a styrofoam container inside the freeezer, to even things out when the cycling happens | 10:39 |
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| yashgaroth | chido: a standard kitchen fridge/freezer is fine, -80 isn't worth the hassle | 11:23 |
| Jenda` | yashgaroth: I guess we need something smaller. | 11:25 |
| Jenda` | yashgaroth: We have standard fridge and other hackerspace members don't really appreciate using it for storing chemicals :) | 11:26 |
| @kanzure | don't store food & chemicals in the same fridge | 11:27 |
| yashgaroth | minifridges have freezers sometimes, the important thing is that it's frozen, not that it reaches -20 necessarily | 11:27 |
| yashgaroth | ehhh most of that stuff is harmless, unless they're keeping a bottle of BME in the fridge next to the milk | 11:29 |
| yashgaroth | but it's best not to draw the ire of the other members | 11:30 |
| @kanzure | insert standard horror story about idiot lab coworker storing p32 next to your yogurt | 11:30 |
| yashgaroth | man no one's used radioisotopes since the 90's | 11:31 |
| @kanzure | erm.. what? | 11:31 |
| yashgaroth | ok well I'm sure someone's still using it, but not for anything diy related | 11:32 |
| @kanzure | all the molecular biology labs i've seen use it.. i think even genspace uses it | 11:32 |
| Jenda` | p32 is a plasmid | 11:32 |
| Jenda` | P-32 is phosporus 32 :) | 11:32 |
| @kanzure | bah | 11:32 |
| @kanzure | P-32, yes. | 11:32 |
| yashgaroth | wait which one are you referring to | 11:32 |
| Jenda` | Good question :) | 11:32 |
| yashgaroth | plasmids are fine, I'd be more worried about food getting into/onto the tube, than the other way around | 11:33 |
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| nmz787 | ahh, keygen music :D | 11:59 |
| Mokbortolan_ | I liked the one that lets you burn stuff | 12:02 |
| Mokbortolan_ | that was an awesome plasmid | 12:02 |
| nmz787 | plasmid laser??? | 12:03 |
| yashgaroth | damn sploicers | 12:03 |
| Mokbortolan_ | :p | 12:04 |
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| nmz787 | trogdor, whats up? | 12:31 |
| Burninate | Just a dragon trying to make it in the world | 12:34 |
| @kanzure | as a part time dragon slash father, i feel that <promotional statement goes here> | 12:42 |
| augur_ | anyone know of any tutorials that introduce self assembly? | 12:43 |
| nmz787 | dna origami | 12:50 |
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| nmz787 | 4 color vision in some species (humans too) http://en.wikipedia.org/wiki/Tetrachromacy | 14:44 |
| ThomasEgi | now that sounds interesting... and would totaly demand a new HD-colorspace-standard | 15:04 |
| ThomasEgi | looking at a regular screen those people are probably like "my eyes, the pixels do nothing" | 15:05 |
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| ThomasEgi | anyone in here who can translate a few sentences of norway language? google fails me a bit. | 15:55 |
| @kanzure | copenhagen suborbitals liquid propellant rocket engine series: | 16:34 |
| @kanzure | http://www.youtube.com/watch?v=bqASqda0ylc | 16:34 |
| @kanzure | http://www.youtube.com/watch?v=i1pRXKewNfM | 16:34 |
| @kanzure | http://www.youtube.com/watch?v=V6Zat0-NlZ0 | 16:34 |
| @kanzure | manned test? http://www.youtube.com/watch?v=USPuRwp-kRw | 16:34 |
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| @fenn | hehe watching that "chi" magician video, at 5:00 you see the narrator with an eye patch, so much for chi therapy on his eye | 18:13 |
| @kanzure | or 50% success rate | 18:17 |
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| @fenn | and his brother is dead, so more like 0% success rate | 18:26 |
| @fenn | all this from an intentional mistranslation... sigh | 18:29 |
| @kanzure | eh? you checked on the brother? | 18:35 |
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| @fenn | it was mentioned in the video at some point | 18:43 |
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| n_bentha | Hey kanz :-) | 19:57 |
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| @kanzure | "Between the day of indictment and 24 February, library.nu redirected to Google Books. The URL gigapedia.com currently links to an article "The disappearing virtual library" by Christopher M. Kelty on aljazeera.com" | 22:01 |
| @kanzure | isn't christopher kelty the outlawbio guy? | 22:01 |
| @kanzure | http://www.aljazeera.com/indepth/opinion/2012/02/2012227143813304790.html | 22:02 |
| JackParsons | loljazerra | 22:02 |
| JackParsons | anti american prowest propaganda outlet | 22:02 |
| JackParsons | but hey.. people only believe the propaganda they want to believe | 22:02 |
| JackParsons | it hip to read aljazerra these days | 22:02 |
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| @kanzure | fwiw kelty's book is sorta worth reading if you're bored | 22:03 |
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| JackParsons | aljazerra is the same as fox news | 22:06 |
| JackParsons | makes my knee jerk | 22:06 |
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| -!- mode/##hplusroadmap [+b JackParsons!*@*] by kanzure | 22:06 | |
| -!- mode/##hplusroadmap [+b gl00m!*@*] by kanzure | 22:06 | |
| -!- mode/##hplusroadmap [+b DrJackParsons!*@*] by kanzure | 22:07 | |
| @kanzure | (having said that, i'm sure aljazeera is full of shit) | 22:07 |
| @kanzure | hehe 22:07 <JackParsons> listen i know you have mental problems, but you dont have to take that out on the people around you | 22:07 |
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| @kanzure | blahhh | 22:11 |
| @kanzure | go away | 22:11 |
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| yashgaroth | *!*@*75.105.14.63 | 22:21 |
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| nmz787 | man nyc is crazy, but it makes me think how china is prob 50X NYCs | 22:22 |
| nmz787 | i.e. the masses of people here, stacked up and shit... what are they all doing? | 22:22 |
| yashgaroth | china isn't just a bigger version of kowloon city you know | 22:28 |
| yashgaroth | that would be sweet though, I would totally live in that | 22:28 |
| nmz787 | dunno what that is, but i heard its just high rise projects | 22:34 |
| nmz787 | like, L.A. sized areas | 22:35 |
| strangewarp | nmz787: look up "Kowloon Walled City" and prepare to nerd out over extreme population density | 22:37 |
| strangewarp | re Al Jazeera: Fox News makes itself into a comparison magnet, to destabilize the legitimacy of any lefty news-sources that may sometimes choose to be frank about neoliberal warmongering garbage | 22:42 |
| strangewarp | So far as the H+ project, though, I still weakly believe that it doesn't matter what kind of cat you're using, so long as it catches the mouse | 22:43 |
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| jrayhawk | al jazeera english arose essentially as a result of the failure of the bbc as an international news source | 23:27 |
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| jrayhawk | comparing it to fox news is a bit nutty; fox caters to a national audience and can afford a great deal of nativism and authoritarian manipulation; al jazeera caters to an international audience and makes credible efforts to trump the BBC in terms of editorial quality and objectivity | 23:38 |
| jrayhawk | as a thought excersize, imagine what the audience would be like if you translated fox news to arabic | 23:45 |
| @kanzure | an arabic-speaking american public? | 23:46 |
| jrayhawk | an arabic-speaking qatari public would work better | 23:47 |
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| @kanzure | so it looks like all phd students have abundant amounts of guilt | 23:54 |
| @kanzure | or somehow their advisors are able to use guilt to motivate them? | 23:54 |
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| yashgaroth | that's an odd spelling of "fear" | 23:57 |
| --- Log closed Sat Jun 30 00:00:55 2012 | ||
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