| --- Log opened Sun Jul 22 00:00:15 2012 | ||
| -!- delinquentme [~bob@c-71-236-101-39.hsd1.pa.comcast.net] has quit [Remote host closed the connection] | 00:13 | |
| -!- klafka [~textual@c-67-174-253-229.hsd1.ca.comcast.net] has quit [Quit: Computer has gone to sleep.] | 00:41 | |
| -!- JayDugger [~duggerj@pool-173-74-81-239.dllstx.fios.verizon.net] has joined ##hplusroadmap | 01:17 | |
| -!- AdrianG [~ircname@unaffiliated/amphetamine] has quit [Read error: Connection reset by peer] | 02:00 | |
| -!- AdrianG [~ircname@unaffiliated/amphetamine] has joined ##hplusroadmap | 02:01 | |
| -!- Tukotih [~Tukotih@81-231-85-111-no39.tbcn.telia.com] has joined ##hplusroadmap | 02:04 | |
| -!- lichen [~lichen@c-24-21-206-64.hsd1.or.comcast.net] has joined ##hplusroadmap | 02:07 | |
| -!- ThomasEgi [~thomas@pppdyn-15.stud-ko.rz-online.net] has joined ##hplusroadmap | 03:00 | |
| -!- ThomasEgi [~thomas@pppdyn-15.stud-ko.rz-online.net] has quit [Changing host] | 03:00 | |
| -!- ThomasEgi [~thomas@panda3d/ThomasEgi] has joined ##hplusroadmap | 03:00 | |
| -!- sylph_mako [~mako@229.100.252.27.dyn.cust.vf.net.nz] has quit [Ping timeout: 245 seconds] | 03:29 | |
| fenn | interesting discounting method (25-year-olds are valued most) http://en.wikipedia.org/wiki/Disability-adjusted_life_year | 04:35 |
|---|---|---|
| fenn | if only there were a way to make old people suck less | 04:35 |
| fenn | fun fact of the day: owsley stanley aka "the king of acid" ate "almost nothing but meat, eggs, butter and cheese since 1959" | 04:40 |
| fenn | he died in a car crash at age 76 | 04:40 |
| fenn | so unfortunately we don't get to see the effects of his diet on lifespan | 04:41 |
| fenn | i used to talk to an audio tech from australia in ##robotics named theBear.. weird. | 04:44 |
| -!- qnm [~qnm@2001:44b8:3110:f300:208:9bff:fec0:179a] has quit [Ping timeout: 246 seconds] | 04:54 | |
| -!- qnm [~qnm@2001:44b8:3110:f300:208:9bff:fec0:179a] has joined ##hplusroadmap | 04:56 | |
| yorick | kanzure: why am I a node.js op‽ | 04:57 |
| -!- OldCoder_ [~OldCoder_@c-69-181-140-134.hsd1.ca.comcast.net] has quit [Quit: Leaving] | 05:08 | |
| -!- OldCoder_ [~OldCoder_@c-69-181-140-134.hsd1.ca.comcast.net] has joined ##hplusroadmap | 05:08 | |
| -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap | 05:09 | |
| -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Ping timeout: 245 seconds] | 05:19 | |
| -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap | 05:20 | |
| -!- smeaaagle [~smeaaagle@2002:6ca6:4fb1::6ca6:4fb1] has quit [Ping timeout: 240 seconds] | 05:34 | |
| -!- smeaaagle [~smeaaagle@2002:6ca6:4fb1::6ca6:4fb1] has joined ##hplusroadmap | 05:39 | |
| -!- Charlie_ [~quassel@64.31.59.70] has joined ##hplusroadmap | 06:04 | |
| -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Ping timeout: 248 seconds] | 06:14 | |
| -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap | 06:14 | |
| -!- delinquentme [~asdfasdf@c-71-236-101-39.hsd1.pa.comcast.net] has joined ##hplusroadmap | 06:42 | |
| delinquentme | Hio! | 06:42 |
| delinquentme | nanotube printed micro circuits? | 07:20 |
| delinquentme | development of automated deposition techniques for making chips? | 07:21 |
| -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Ping timeout: 245 seconds] | 07:47 | |
| -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap | 07:48 | |
| -!- delinquentme [~asdfasdf@c-71-236-101-39.hsd1.pa.comcast.net] has quit [Ping timeout: 264 seconds] | 08:01 | |
| -!- JayDugger [~duggerj@pool-173-74-81-239.dllstx.fios.verizon.net] has quit [Quit: Leaving.] | 08:03 | |
| -!- delinquentme [~asdfasdf@c-71-236-101-39.hsd1.pa.comcast.net] has joined ##hplusroadmap | 08:16 | |
| -!- delinquentme [~asdfasdf@c-71-236-101-39.hsd1.pa.comcast.net] has quit [Quit: Leaving] | 08:26 | |
| -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Ping timeout: 248 seconds] | 08:26 | |
| -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap | 08:26 | |
| -!- klafka [~textual@c-67-174-253-229.hsd1.ca.comcast.net] has joined ##hplusroadmap | 08:55 | |
| -!- splicer [~ubuntu@c83-255-190-140.bredband.comhem.se] has quit [Ping timeout: 240 seconds] | 08:59 | |
| -!- klafka [~textual@c-67-174-253-229.hsd1.ca.comcast.net] has quit [Quit: Computer has gone to sleep.] | 09:05 | |
| -!- ThomasEgi [~thomas@panda3d/ThomasEgi] has quit [Ping timeout: 260 seconds] | 09:06 | |
| -!- splicer [~ubuntu@c83-255-190-140.bredband.comhem.se] has joined ##hplusroadmap | 09:11 | |
| -!- augur [~augur@c-75-74-129-116.hsd1.fl.comcast.net] has quit [Ping timeout: 246 seconds] | 09:17 | |
| -!- ThomasEgi [~thomas@pppdyn-72.stud-ko.rz-online.net] has joined ##hplusroadmap | 09:19 | |
| -!- ThomasEgi [~thomas@pppdyn-72.stud-ko.rz-online.net] has quit [Changing host] | 09:19 | |
| -!- ThomasEgi [~thomas@panda3d/ThomasEgi] has joined ##hplusroadmap | 09:19 | |
| -!- delinquentme [~asdfasdf@c-71-236-101-39.hsd1.pa.comcast.net] has joined ##hplusroadmap | 09:25 | |
| -!- exiff [~gennosuke@unaffiliated/exiff] has quit [Ping timeout: 255 seconds] | 09:36 | |
| delinquentme | http://www.bostonglobe.com/business/2012/07/21/can-custom-dna-maker-gen-become-intel-biotech-revolution/bTC0zaHBaAqLKfcjvUoLVO/story.html?s_campaign=sm_tw | 09:43 |
| -!- klafka [~textual@c-67-174-253-229.hsd1.ca.comcast.net] has joined ##hplusroadmap | 09:50 | |
| -!- klafka [~textual@c-67-174-253-229.hsd1.ca.comcast.net] has quit [Read error: Connection reset by peer] | 09:53 | |
| -!- klafka [~textual@c-67-174-253-229.hsd1.ca.comcast.net] has joined ##hplusroadmap | 09:53 | |
| -!- klafka1 [~textual@c-24-6-18-31.hsd1.ca.comcast.net] has joined ##hplusroadmap | 09:53 | |
| kanzure | fenn: i don't understand theBear comment you made? | 09:54 |
| kanzure | delinquentme: stop reading news :P | 09:54 |
| delinquentme | haha | 09:55 |
| delinquentme | i know dude I'm hankering for a new project | 09:55 |
| delinquentme | I wish smaller mechano-electrical components were cheaper | 09:55 |
| delinquentme | also I really wanna get a reprap | 09:55 |
| delinquentme | and you see what carlson said about the market for synthetic DNA is unproven? | 09:56 |
| delinquentme | seemed like a premature comment? | 09:56 |
| delinquentme | I tweeted at him saying that we dont really have a huge market *troubleshooting* working organisms | 09:56 |
| delinquentme | which would be where you're going to blow through synthetic DNA | 09:56 |
| -!- klafka [~textual@c-67-174-253-229.hsd1.ca.comcast.net] has quit [Ping timeout: 260 seconds] | 09:57 | |
| -!- exiff [~gennosuke@dsl-243-65-193.telkomadsl.co.za] has joined ##hplusroadmap | 10:08 | |
| -!- exiff [~gennosuke@dsl-243-65-193.telkomadsl.co.za] has quit [Changing host] | 10:08 | |
| -!- exiff [~gennosuke@unaffiliated/exiff] has joined ##hplusroadmap | 10:08 | |
| -!- augur [~augur@c-75-74-129-116.hsd1.fl.comcast.net] has joined ##hplusroadmap | 10:11 | |
| delinquentme | kanzure, is there an industry standard for microfluidic 3d modelling yet? | 10:21 |
| kanzure | everyone just uses autocad | 10:25 |
| kanzure | i prefer svg | 10:25 |
| -!- klafka1 [~textual@c-24-6-18-31.hsd1.ca.comcast.net] has quit [Quit: Computer has gone to sleep.] | 11:19 | |
| * Mokbortolan_1 uses sketchup. | 12:02 | |
| delinquentme | http://io9.com/5928050/3d-printing-technology-could-let-you-print-your-pharmaceuticals-at-home | 12:28 |
| delinquentme | im sorry I dont get how this works | 12:28 |
| delinquentme | we're talking about pharma companie who spend years developing molecules | 12:28 |
| delinquentme | and with only a few compounds we can create them at home? | 12:29 |
| delinquentme | somethings missing for me. | 12:29 |
| -!- klafka [~textual@c-67-174-253-229.hsd1.ca.comcast.net] has joined ##hplusroadmap | 12:36 | |
| -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Ping timeout: 252 seconds] | 12:40 | |
| -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap | 12:40 | |
| AdrianG | delinquentme: create known compounds maybe | 13:01 |
| AdrianG | researching involves a lot more than final synthesis of a well-tested compound. | 13:01 |
| delinquentme | AdrianG, I guess what im surprised about is that they're saying we can create pharmaceuticals with only a few compounds at varying temps / concentrations? | 13:05 |
| delinquentme | I guess I know nothing about pharma .. but I thought the compounds were all wildly exotic | 13:06 |
| AdrianG | not really | 13:06 |
| AdrianG | most oral agents satisfiedy the criteria of five | 13:07 |
| AdrianG | http://en.wikipedia.org/wiki/Lipinski%27s_rule_of_five | 13:07 |
| AdrianG | injectables is a whole other story | 13:07 |
| AdrianG | say, making old orally active pharmaceuticals, say like methamphetamine hcl is very simple | 13:08 |
| AdrianG | can be done in any trailer | 13:08 |
| AdrianG | now, synthesizing interferon is a bit more difficult | 13:08 |
| kanzure | it is well known that fist of the north star was able to synthesize interferon just by nodding | 13:16 |
| kanzure | shortest synthetic route known. | 13:16 |
| brownies | i am convinced there are literally like 6 people who ever played that video game | 13:31 |
| brownies | and somehow i've met all of them. | 13:31 |
| kanzure | somehow my flask app started working | 13:32 |
| kanzure | i wasn't expecting it to work but it did and now i'm confused | 13:32 |
| -!- eudoxia [~eudoxia@r186-52-129-1.dialup.adsl.anteldata.net.uy] has joined ##hplusroadmap | 14:11 | |
| -!- Sanqui [~SankyZNC@unaffiliated/sanky] has quit [Read error: Connection reset by peer] | 14:16 | |
| -!- Sanky [~SankyZNC@unaffiliated/sanky] has joined ##hplusroadmap | 14:17 | |
| -!- superkuh [~superkuh@unaffiliated/superkuh] has quit [Quit: rebooting to play DayZ.] | 14:43 | |
| -!- AdrianG [~ircname@unaffiliated/amphetamine] has quit [Ping timeout: 248 seconds] | 14:44 | |
| -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Ping timeout: 245 seconds] | 14:45 | |
| -!- delinquentme [~asdfasdf@c-71-236-101-39.hsd1.pa.comcast.net] has quit [Ping timeout: 264 seconds] | 14:54 | |
| -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap | 15:00 | |
| -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Ping timeout: 264 seconds] | 15:18 | |
| -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap | 15:19 | |
| -!- nsh [~crunchban@wikipedia/nsh] has joined ##hplusroadmap | 15:30 | |
| -!- eudoxia [~eudoxia@r186-52-129-1.dialup.adsl.anteldata.net.uy] has quit [Ping timeout: 252 seconds] | 16:01 | |
| -!- nsh [~crunchban@wikipedia/nsh] has quit [Remote host closed the connection] | 16:16 | |
| -!- rmcl [~rmcl@99-71-136-35.lightspeed.sndgca.sbcglobal.net] has joined ##hplusroadmap | 16:34 | |
| -!- rmcl [~rmcl@99-71-136-35.lightspeed.sndgca.sbcglobal.net] has quit [Quit: rmcl] | 16:46 | |
| -!- Steel2 [ad42e490@gateway/web/freenode/ip.173.66.228.144] has joined ##hplusroadmap | 16:51 | |
| -!- klafka1 [~textual@c-24-6-18-31.hsd1.ca.comcast.net] has joined ##hplusroadmap | 16:57 | |
| -!- klafka [~textual@c-67-174-253-229.hsd1.ca.comcast.net] has quit [Ping timeout: 255 seconds] | 16:59 | |
| -!- exiff [~gennosuke@unaffiliated/exiff] has quit [Ping timeout: 255 seconds] | 17:12 | |
| -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Quit: Leaving] | 17:18 | |
| -!- rmcl [~rmcl@99-71-136-35.lightspeed.sndgca.sbcglobal.net] has joined ##hplusroadmap | 17:38 | |
| -!- nsh [~Smedley@wikipedia/nsh] has joined ##hplusroadmap | 17:52 | |
| -!- ThomasEgi [~thomas@panda3d/ThomasEgi] has quit [Remote host closed the connection] | 18:07 | |
| -!- delinquentme [~asdfasdf@c-71-236-101-39.hsd1.pa.comcast.net] has joined ##hplusroadmap | 18:23 | |
| delinquentme | could the Fourier transform be used in data compression? | 18:30 |
| delinquentme | yes. | 18:33 |
| * nsh nods | 18:34 | |
| delinquentme | I havnt read the research completely ... anyone know how hard this is to implement? | 18:35 |
| nsh | depends what you want to compress, and under what criteria | 18:36 |
| nsh | a trivial example is audio, if you transform to the frequency domain, truncate frequencies higher than some cutoff, then transform back | 18:37 |
| nsh | you've done some lossy compression | 18:37 |
| delinquentme | oh but then this is kind of a lossy compression method? | 18:38 |
| delinquentme | Like im thinking through the possibilities for sending genomics data | 18:38 |
| delinquentme | I guess you could chop the thing up into pieces and SHA1 sum each portion | 18:39 |
| delinquentme | resend those which dont check out | 18:39 |
| nsh | there are probably existing solutions | 18:40 |
| nsh | that would be difficult to improve upon without relevant expertise and experience | 18:40 |
| -!- strages_home [~strages@adsl-98-67-175-61.shv.bellsouth.net] has quit [Ping timeout: 264 seconds] | 18:49 | |
| -!- Steel2 [ad42e490@gateway/web/freenode/ip.173.66.228.144] has quit [Ping timeout: 245 seconds] | 19:00 | |
| -!- strages_home [~strages@adsl-98-67-175-61.shv.bellsouth.net] has joined ##hplusroadmap | 19:10 | |
| kanzure | "FIST OF THE DEATH STAR: ALDERAAN IS ALREADY DEAD" | 19:19 |
| * nsh blinks | 19:20 | |
| kanzure | nsh: just updating my playlists.. http://www.youtube.com/playlist?list=PL85F050BEFA28E044 | 19:23 |
| delinquentme | are there existing SUPER compression tools for genomics data sets? | 19:25 |
| delinquentme | kanzure, did i tell you about backblaze? | 19:25 |
| delinquentme | I emailed them and apparently theyve got not genomics clients | 19:25 |
| kanzure | yes you can print out the dna and mail it to them | 19:26 |
| kanzure | it's much higher information density | 19:26 |
| delinquentme | thats an interesting idea | 19:26 |
| delinquentme | but they've got to resequence it | 19:26 |
| delinquentme | that takes time | 19:26 |
| kanzure | so do other decompression algorithms | 19:26 |
| delinquentme | true but not as much as sequencing | 19:26 |
| delinquentme | but heres the idea | 19:26 |
| delinquentme | ACTGs can be represented as 2 bits | 19:27 |
| delinquentme | 00, 01, 10, and 11 | 19:27 |
| kanzure | are you familiar with how zip, gzip or bzip works? | 19:27 |
| delinquentme | lets say we arbitrarily pick which represents the nucleotide | 19:27 |
| delinquentme | nah not at all | 19:27 |
| delinquentme | which was what I was about to check | 19:27 |
| kanzure | you should read up on compression algorithms. | 19:27 |
| delinquentme | ( to see if there are awesome compression tools which exist ) | 19:27 |
| kanzure | until lzra makes sense | 19:27 |
| delinquentme | Latvian Association of Certified Auditors | 19:28 |
| delinquentme | nope i missed that part | 19:28 |
| kanzure | lzma | 19:28 |
| kanzure | lempel-zimmersomething markov chain somethingsomething | 19:29 |
| delinquentme | but I think we can agree that a compression SPECIFICALLY for some data type | 19:29 |
| delinquentme | would be better than general compression | 19:29 |
| delinquentme | ( humor me if you would ) | 19:29 |
| delinquentme | My question to the #bioinformatics kids is: " Does this massive string of the genome have a use ?" | 19:30 |
| delinquentme | or does it need to contain all of the other FASTA related material / annotations to be useful | 19:30 |
| kanzure | what do you mean by useful? | 19:30 |
| kanzure | annotations are usually stored on ncbi's servers | 19:31 |
| delinquentme | so useful is kind of the part where " can I make a service that people will pay for by combining ... | 19:31 |
| delinquentme | 1) Automated / cheap backblaze based storage | 19:31 |
| kanzure | maybe you should study compression before monetizing your nonexistent algorithm | 19:32 |
| delinquentme | 2) A 2 bit compression process for *only* the genome string | 19:32 |
| delinquentme | but like for storage of someones genome | 19:32 |
| delinquentme | you're going to have all the HG18 related information handy right? | 19:32 |
| delinquentme | you're simply comparing that individuals genome string against that standard template | 19:33 |
| kanzure | huref isn't always #18 | 19:33 |
| delinquentme | sure sure | 19:33 |
| delinquentme | but I'm curious if that has any value | 19:33 |
| kanzure | you seem to be against symbol tables, but this is exactly what you are describing | 19:33 |
| kanzure | not sure i can help you man | 19:33 |
| delinquentme | this is the part where I think you're talking compression | 19:33 |
| delinquentme | It was kind of my shot in the dark guess that no ones built out a 2-bit compression for *just* the genome string | 19:34 |
| kanzure | i forget the name of one implementation of that | 19:34 |
| delinquentme | god im so hungry i might eat a salad | 19:37 |
| nsh | .wik LZMA | 19:38 |
| -!- hplunny [~hplunny@host86-132-221-146.range86-132.btcentralplus.com] has joined ##hplusroadmap | 19:46 | |
| nsh | .wik LZMA | 19:46 |
| hplunny | "The Lempel–Ziv–Markov chain algorithm (LZMA) is an algorithm used to perform lossless data compression." - http://en.wikipedia.org/wiki/LZMA | 19:46 |
| -!- hplunny [~hplunny@host86-132-221-146.range86-132.btcentralplus.com] has quit [Remote host closed the connection] | 19:48 | |
| * nsh notes to self for the second time that if you copy an address to clipboard from chrome, then close the window, it disappears | 19:49 | |
| nsh | annoyingly. | 19:49 |
| kanzure | nsh: xclip -sel or the other one | 19:50 |
| kanzure | xclip -sel | pastebinit is my goto method. | 19:50 |
| nsh | ty | 19:51 |
| -!- AdrianG_ [~ircname@unaffiliated/amphetamine] has joined ##hplusroadmap | 20:08 | |
| -!- AdrianG_ is now known as AdrianG | 20:09 | |
| -!- azonenberg [~azonenber@2001:470:888b:2:206:70ff:fe01:46] has quit [Ping timeout: 245 seconds] | 20:32 | |
| delinquentme | Umm machine which measures light output ina 96 well plate? | 20:38 |
| delinquentme | kanzure, do you know if 7zip is the default ubuntu compression tool? | 20:51 |
| delinquentme | lulz nm | 20:52 |
| -!- azonenberg [~azonenber@2001:470:888b:2:206:70ff:fe01:46] has joined ##hplusroadmap | 21:21 | |
| -!- exiff [~gennosuke@dsl-243-61-62.telkomadsl.co.za] has joined ##hplusroadmap | 21:34 | |
| -!- exiff [~gennosuke@dsl-243-61-62.telkomadsl.co.za] has quit [Changing host] | 21:34 | |
| -!- exiff [~gennosuke@unaffiliated/exiff] has joined ##hplusroadmap | 21:34 | |
| -!- calango [~dnm@pdpc/supporter/active/calango] has joined ##hplusroadmap | 22:24 | |
| -!- superkuh [~superkuh@unaffiliated/superkuh] has joined ##hplusroadmap | 22:35 | |
| -!- rmcl [~rmcl@99-71-136-35.lightspeed.sndgca.sbcglobal.net] has quit [Quit: rmcl] | 22:41 | |
| -!- exiff [~gennosuke@unaffiliated/exiff] has quit [Ping timeout: 255 seconds] | 22:42 | |
| -!- delinquentme [~asdfasdf@c-71-236-101-39.hsd1.pa.comcast.net] has quit [Ping timeout: 260 seconds] | 22:47 | |
| -!- AdrianG [~ircname@unaffiliated/amphetamine] has quit [Ping timeout: 248 seconds] | 23:30 | |
| -!- srangewarp [~strangewa@c-76-25-200-47.hsd1.co.comcast.net] has joined ##hplusroadmap | 23:32 | |
| -!- strangewarp [~strangewa@c-76-25-200-47.hsd1.co.comcast.net] has quit [Ping timeout: 245 seconds] | 23:34 | |
| -!- srangewarp is now known as strangewarp | 23:34 | |
| -!- calango [~dnm@pdpc/supporter/active/calango] has quit [Quit: Leaving] | 23:46 | |
| -!- nathaniel [~nathaniel@reddit/operator/nathaniel] has joined ##hplusroadmap | 23:56 | |
| --- Log closed Mon Jul 23 00:00:16 2012 | ||
Generated by irclog2html.py 2.15.0.dev0 by Marius Gedminas - find it at mg.pov.lt!