2013-01-31.log

--- Log opened Thu Jan 31 00:00:46 2013
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archelshttp://www.arboria.org/trailer/01:12
archelsoh heck, it's been out since 201001:13
* archels finds a torrent01:13
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archelspaperbot: http://chaos.aip.org/resource/1/chaoeh/v18/i1/p015115_s102:08
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archelshttp://www.imdb.com/title/tt1710927/09:52
eudoxiai hope it's better than the title09:54
nmz787heh09:55
nmz787i like that one of the actors has my name09:55
chris_99http://vimeo.com/21568412 trailer10:00
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nmz787looks like it could be decent10:24
@kanzureah those fuckers moved the diybio eu mailing list10:26
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nmz787mac is weird, he doesn't like replying to emails about stuff he's working on10:46
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juri_point me to someone here who is not wierd. :)11:17
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nmz787paperbot: http://www.nature.com/ja/journal/v62/n9/full/ja200976a.html13:08
paperbotHTTP 401 unauthorized http://www.nature.com/ja/journal/v62/n9/pdf/ja200976a.pdf13:08
@kanzurepaperbot: http://www.bioone.org/doi/full/10.3732/apps.120049713:10
paperboterror: HTTP 500 http://diyhpl.us/~bryan/papers2/paperbot/673d924ffaf661f04f20962d8c3d3d63.txt13:10
nmz787'The idea is, after you eat a meal and wait 20 minutes (to let your food digest and get liquified and evenly dispersed) you then use the pump to remove 30 percent of your stomach contents. [I have no idea how it is able to gauge what 30 percent of your stomach contents are, but then again I dont know how a Segway works either.] You then spray these contents into a suitable disposal apparatus such as your toilet, or if you are an animal lover, a baby 13:14
nmz787http://www.aspirebariatrics.com/about-the-aspireassist.html13:15
nmz787'The quick, 20 minute procedure is performed under conscious sedation  no general anesthesia is required.  '13:17
nmz787'Reversible. The AspireAssist can be removed, at any time, through a 15-minute outpatient procedure. It is performed under conscious sedation.13:17
nmz787'13:17
@kanzurehaha scifinder is broken since browsers are blocking java now13:24
@kanzureawesome13:24
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@kanzurei think the github contributions calendar is shifting each day?14:33
@kanzureat the moment the calendar starts at 2012-01-31 (tuesday)14:34
@kanzureleaving two blank cells for the previous two days14:34
browniesit shifts up? or left? or both?14:37
@kanzuremy visual acuity is unable to resolve movement over multiple days. maybe i should take some screenshots.14:37
@kanzuremy new plan is to push a single letter at a time. the "E" has been there for a few days now and the other letters weren't showing up.14:38
@kanzurealso, i checked my input and the "E" was supposed to be at least 1 cell from the bottom. so i'm not sure why github was rendering it at the bottom. :(14:38
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nmz787ok so using the apache directory page index, i just threw together this gallery using galleria15:46
nmz787http://nathanmccorkle.com/takeAparts/hybaid/gallery.html15:47
nmz787so i can just drop gallery.html into any directory of images I have!15:47
nmz787well, actually it was too slow without thumbnails, so i guess i have to always provide them as well15:48
nmz787i guess i should add a fallback for 'thumb not present'15:49
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@kanzurehttp://ieet.org/index.php/IEET/more/miah2013013116:34
@kanzurehaha andy miah16:34
@kanzurewell at least he has published an opinion that might be potentially relevant, for once.16:35
@kanzurehttp://www.wired.co.uk/news/archive/2013-01/30/lance-armstrong16:35
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nmz787yashgaroth: sup17:57
yashgarothyo17:57
nmz787how's everything been?17:57
yashgarothgood, I'd say17:58
nmz787i saw SD got that lifetech bldg?17:58
yashgarothhells yes17:58
nmz787got any first projects plannd?17:58
yashgarothoh you know, myostatin inhibition and some shit about algae someone's doing17:58
nmz787like doing the toxin purification from ecoli plasmid?17:59
yashgarothtoxin?17:59
nmz787err plasmid purification via removing endotoxin17:59
nmz787*along with*17:59
nmz787i remember you saying you needed a maxiprep17:59
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nmz787but that the endotoxin needed scrubbed17:59
yashgarothyeah as it turns out I have a line on a process that works pretty well18:00
nmz787cool18:00
yashgarothyou can mix in some triton x-100 or -114, and apparently wash the column with ethanol to remove the rest18:00
yashgarothmy main concern now it getting them sweet optimized plasmid backbones18:01
yashgarothpeople working on some pretty nice promoter/enhancer/synthetic intron/etc combos that I wanna get my hands on18:01
yashgarothalso some sort of arduino-based bioreactor, though that's not critical18:01
nmz787well i just got parts for a reactor myself18:02
nmz787RH, temp sens and control18:02
nmz787and found a good CO2 meter18:02
nmz787like $150 in parts18:02
yashgarothI need an e.coli one, so dissolved oxygen and pH sensors, with a way to inject O2 and feed and acid/base18:03
nmz787oh 192 atually https://docs.google.com/spreadsheet/ccc?key=0AkTsdtdxo56DdFpYU2RzVHVIYk4xbnVWNFVoUzlqclE#gid=018:03
nmz787ahh18:04
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yashgaroththey do dissolved CO2?18:04
nmz787it would be easier to measure CO218:04
yashgarothyeah but e.coli don't give a fuck about CO218:04
nmz787you could prob just sample the air if you aerate it well enough18:04
nmz787dont they emit it thou18:04
yashgarothyeah but they can deal with it18:04
yashgaroththe sensor's gonna get soaked in a lot of media even if it's suspended above though18:05
nmz787i would think you could infer o2 consumption based on co2 differentials18:05
nmz787nah you could have some tyvek or somthing18:05
nmz787plus its optical18:05
nmz787NDIR18:05
yashgarothmaybe, if CO2 sensing is that much easier18:06
nmz787http://www.co2meter.com/collections/co2-sensors/products/k-30-co2-sensor-module18:06
nmz787has an arduino code snippet18:06
yashgarothone of the downsides of reading papers that have much higher funding than us18:06
yashgarothhowever it does have upsides since we don't need to be anal about autoclaving18:07
nmz787"Roughly, for every mole of O218:07
nmz787 taken up by a cell, 1 mole of carbon dioxide, CO218:07
nmz787, is produced.  "18:07
nmz787http://www.merrick.com/merrickandcompany/media/Resources/Energy/Whitepapers/Stirred-Bioreactor-Engineering-for-Production-Scale-Part-1.pdf?ext=.pdf18:07
yashgarothyou'd have to do some inference on translating that into how much O2 to inject, but it might be doable18:07
yashgaroththen again I've also been considering running it at low temp for a really long time instead, would reduce the need for extra oxygen perhaps entirely18:09
yashgarothinoculate, come back a week later instead of 24 hours, no problem for me18:09
yashgarothextra problem is that almost all of this research is industry-funded, so they either don't publish, or pimp their own method to get sales18:11
yashgarothhigh-density e.coli cultures, that is18:13
nmz787mm18:13
nmz787what about a pH dye?18:15
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nmz787is there a reason to not just always bubble in air?18:16
yashgarothif you can get good agitation with stirring, it might not be necessary18:16
yashgarotha pH dye might work, but with the e.coli densities you'd be getting, it might get hard to see18:17
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@kanzureanyone know who this is? https://github.com/antped8418:52
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@kanzure"In December nine polio vaccinators in Pakistan were murdered."19:43
@kanzurehttp://annualletter.gatesfoundation.org/#nav=section4&slide=019:43
@kanzurehaha his last survey question is "How trustworthy do you consider Bill Gates to be?"19:50
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@kanzurei think some of my productivity might be correlated to weather20:56
@kanzureat first i was thinking humidity, but the weather data doesn't seem to support that20:56
@kanzureplus, it doesn't feel like average humidity is the reason20:56
@kanzurei seem to write the most code during thunderstorms, but some of the summer thunderstorms dont count20:57
@kanzurewhat other weather measurement should i look at?20:57
yashgarothtry rainymood in the background, also barometric pressure20:57
@kanzurebarometric! /me checks20:58
@kanzureeh, i doubt it's barometric pressure, unless it's something about inflection points over multiple days. which i hope it's not.20:59
yashgarothit seemed unlikely; maybe pollen count?21:00
@kanzureoh actually relative humidity looks fairly accurate http://w1.weather.gov/obhistory/KAUS.html21:00
@kanzureanything above 20% and i'm shot? that would suck.21:00
yashgarothlairs of doom in a desert just don't have the same feel21:01
@kanzure"High levels of humidity lowered scores on concentration while increasing reports of sleepiness." http://en.wikipedia.org/wiki/Meteoropathy21:05
@kanzurepaperbot: http://www.tandfonline.com/doi/abs/10.1080/00221309.1982.970991721:07
paperbotno translator available, raw dump: http://diyhpl.us/~bryan/papers2/paperbot/41e6d0abe8b8b055978f4ed0548c74b1.txt21:07
@kanzurepaperbot: http://www.tandfonline.com/doi/pdf/10.1080/00221309.1982.970991721:08
paperbotno translator available, raw dump: http://diyhpl.us/~bryan/papers2/paperbot/f17ae3b90479b2f05c6416c154a78e10.pdf21:08
@kanzureewww watermarks.21:08
@kanzure"Southern folk wisdom" god damn it21:09
@kanzurepaperbot: http://www.sciencedirect.com/science/article/pii/S036013230600375121:11
paperbotno translator available, raw dump: http://diyhpl.us/~bryan/papers2/paperbot/Effect%20of%20humidity%20on%20human%20comfort%20and%20productivity%20after%20step%20changes%20from%20warm%20and%20humid%20environment.pdf21:11
@kanzure"Subjective experiments were conducted to evaluate the effects of humidity on human comfort and productivity under transient conditions from hot and humid environment to thermally neutral condition. Two climate chambers, “Chamber 1” and “Chamber 2”, adjoined each other were used for this study."21:11
@kanzure"Subjects were exposed to 30 °C/70%RH air in Chamber 1 for 15 min with 2.0 met of metabolic rate. Then they moved into Chamber 2, where 4 humidity conditions, 30, 40, 50 and 70%RH were examined."21:11
@kanzure"ir temperature was adjusted to keep SET* constant at 25.2 °C for all conditions. Subjects were exposed in Chamber 2 for 180 min performing 2 kinds of simulated office work."21:11
@kanzurehrm. well that's unfortunate (no gains in typing rate, although their setup was bizarre).21:32
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jrayhawkpaperbot: http://link.springer.com/article/10.1023%2FA%3A101563712750422:02
paperboterror: HTTP 500 http://diyhpl.us/~bryan/papers2/paperbot/Schumann%20Resonances%2C%20a%20plausible%20biophysical%20mechanism%20for%20the%20human%20health%20effects%20of%20Solar.pdf22:02
jrayhawkhooray22:02
@kanzuremaybe paperbot should have better error messages22:03
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@kanzurehttps://angel.co/markets22:21
@kanzurehttps://angel.co/life-sciences22:21
@kanzurei see transcriptic and cambrian genomics listed22:21
@kanzure"benchling: github of biology".. yawn, i wish they would actually implement fucking git.22:21
@kanzure"axio: Revolutionary method for objectively improving mental performance" uhuh..22:22
@kanzurewhy is openpcr listed as a company?22:22
yashgaroth"Aerin Medical: Stealth" does this mean they aren't releasing any info or do they do camouflaged surgery22:23
@kanzureaxio seems to work by eeg, how the fuck is that revolutionary22:23
@kanzurewhat the hell22:23
@kanzure"brainwaves"....22:23
yashgarothwell you see, brainwaves can22:23
@kanzure"Neural Disruption, Inc. we disrupt your brain by driving 2 meter rods through your skull"22:24
jrayhawkthere's nothing revolutionary about neurofeedback22:26
@kanzure"EnChroma makes glasses that improve how all humans see color, and are the only solution to help to the 10 million Americans suffering from red/green color blindness. We implemented insights gleaned from our NIH sponsored research on improving human color vision through selective spectral filtration in a sunglass product."22:30
yashgarothso it blocks red or green light22:31
yashgarothbut which one?! that's where the money's at22:31
browniesjust wait for them to file a patent, then build the other one22:38
* AlonzoTG wants to develop the technology to print himself a GF.22:39
yashgarothwhat, I don't even22:40
@kanzure""Just Food100% real food meals for those on feeding tubes. Disrupting the $10B enteral food market."22:41
yashgarothI thought you made that up until I checked22:42
@kanzure"we chew your gourmet food up for you, then puke it up and shove it down your feeding tube"22:43
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browniesthe marketing copy practically writes itself22:46
@kanzurei am not able to load it (browser problems at the moment); can you summarize?22:46
yashgaroth"sales hacker" is apparently a thing that exists, huh22:46
@kanzureit's just madeup bullshit like "ninja hacker pirate"22:46
Hoaxnot to be cynical but these days anytime you want to something to seem clever and edgy you just add the word hacker to the end of it22:47
@kanzurehplusroadmaphackers22:48
yashgarothif I ever start a company and need to hire a janitor I will post the listing for a "cleanliness hacker"22:48
Hoaxwhats sounds cooler "sales associate" or "sales hacker"22:48
@kanzurewho are you22:49
yashgarothmotivational speakers are now "slacker hackers"22:49
Hoaxsorry I'm new22:49
@kanzurehow did you hear about this place?22:49
Hoaxi was loking for transhumanist related roooms and just sorta found it22:50
Hoaxlooking*22:50
HoaxI'm relatively new to it and have just been looking for communities where the ideas are discussed22:51
Hoaxyou guys sounded promising22:51
@kanzureweird, this one is just for reviewing medical equipment? https://procuredhealth.com/23:04
@kanzurethis one seems to do exoskeleton arm things https://angel.co/equipois23:04
@kanzurehttp://www.equipoisinc.com/23:05
@kanzure"zeroG is a patented mechanical arm technology that lets workers maneuver tools, parts and other payloads as if weightless, with unmatched freedom of motion."23:05
@kanzureit would be nice to store and download recorded movements for that, although object lock-on probably sucks.23:06
yashgaroththe video on https://angel.co/hourglass-technologies is quite horrifying23:07
@kanzureoh, it's just an articulated jack?23:07
@kanzurethat is less interesting23:07
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@kanzureyashgaroth: what. how does that work. that device makes no sense.23:09
yashgarothI should start one called Angelytics that analyzes the funding effects of putting "disruptive" into the blurb for your company23:09
yashgarothwell you see, our robot overlords will need sustenance23:09
yashgarothanyway I must get some sleep so that video can disruptively haunt my nightmares23:12
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@kanzuremail-in paper blood testing https://angel.co/talking2023:12
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@kanzure"cloud clinical trials" https://angel.co/cloudclinica eh.. yeah i guess most clinical trial service providers are probably not computationally savvy, so i could see this working.23:14
@kanzurebrownies: https://angel.co/luminessence "Our mission is to develop and commercialize a portfolio of globally patented, proprietary, bioluminescent (light producing) protein based products that are edible."23:16
@kanzurebrownies: this probably includes cats23:16
@kanzurethis guy seems to be trying to do dropbox-for-pdfs-but-with-discussion http://www.paper-box.co/23:18
browniesexcellent23:20
@kanzurehttps://angel.co/greenrx "Find the drugs you need. Trade the ones you don't." what.23:22
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@kanzurehttp://www.surgerytheater.com/23:26
@kanzurebone-conduction hearing aid https://angel.co/veryvoice (i thought this already exists?)23:27
browniesi don't think you can do that with drugs23:28
@kanzureah excellent, https://angel.co/organ-transport-systems-1 "The LifeCradle preserves, monitors and transports hearts used in transplantation and will replace the picnic cooler currently used. "23:33
@kanzurebut how about other organs and how about actually using hte organs in a container?23:33
@kanzure"The LifeCradle has been proven in published research at leading academic research centers to significantly extend the life of procured hearts from 4 to 24 hours. Over seventy percent of donated hearts are NOT transplanted in many cases because of a lack of preservation time in the picnic cooler.."23:33
brownies70%? holy hell.23:35
@kanzurebrownies: <1000 artificial hearts are in production at the moment23:36
@kanzure"TripAdvisor for medical tourism" https://angel.co/medisherpa23:36
@kanzurehttp://www.medisherpa.com/23:36
browniesi feel like the artificial heart problem should have been solved by now.23:36
@kanzureit was solved, the artificial heart works23:36
browniesso then what's the problem? why are so few in production?23:37
@kanzurenot sure23:37
brownies=/23:37
@kanzureweird. medisherpa focuses on hotels. i'd be more interested in clinics specializing in certain procedures.23:38
@kanzureis there an online marketplace for patent rights yet?23:47
@kanzurehah https://angel.co/weedmaps-media "yelp for 'medical' marijuana"23:48
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@kanzureanother hilarious "half-baked" one https://angel.co/dankbay23:52
strangewarpnaive guess: heart transplants could prop up some profitable sub-industries that are surviving through inertia and/or dirty tricks23:54
@kanzurei think it's because people realized that heart transplants work23:55
@kanzureman these guys suck at doing things on the web, http://localizedtherapeutics.com/ but they claim to be doing gene therapy with light-controlled gene expression.23:57
@kanzure"Unlike the current commerical formulas that make up the $10 billion enteral market, Just Food meals will not contain corn syrup, additives, preservatives or anything other than real food."23:59
@kanzure.. ah.23:59
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