| --- Log opened Tue Jul 16 00:00:27 2013 | ||
| @fenn | paperbot: http://www.ncbi.nlm.nih.gov/pubmed/15669893 | 00:48 |
|---|---|---|
| @fenn | paperbot: http://article.psychiatrist.com/dao_1-login.asp?ID=10001181&RSID=66614062010005 | 00:51 |
| paperbot | http://diyhpl.us/~bryan/papers2/paperbot/5d8ef27e47939e2d102bc60dd2fa5cfa.txt | 00:51 |
| @fenn | i guess that's a negative | 00:51 |
| nmz787 | try abusing it | 00:52 |
| * fenn slaps paperbot around with a digital trout | 00:53 | |
| nmz787 | yesterday someone said 'touch a fish for good luck' while holding a rubber fish | 00:53 |
| @fenn | that's disgusting | 00:53 |
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| @kanzure | .title http://www.youtube.com/watch?v=sDwQwTDyASA | 06:38 |
| yoleaux | EG]Zeta Gundam Love Is The Pulse Of The Stars(720p 10bit FLAC) - YouTube | 06:38 |
| @kanzure | too much talking :| | 06:38 |
| @kanzure | paperbot: http://dx.doi.org/10.1038/nsmb.2629 | 06:53 |
| @kanzure | .title http://www.bnl.gov/newsroom/news.php?a=11550 | 06:53 |
| yoleaux | BNL Newsroom | Key Step in Molecular 'Dance' that Duplicates DNA Deciphered | 06:53 |
| paperbot | http://diyhpl.us/~bryan/papers2/paperbot/50a86f92583e8128b3d9361e58b1608b.txt | 06:53 |
| @kanzure | paperbot: http://www.nature.com/nsmb/journal/vaop/ncurrent/full/nsmb.2629.html | 06:54 |
| paperbot | http://libgen.org/scimag/get.php?doi=10.1038%2Fnsmb.2629 | 06:54 |
| @kanzure | damn it wtf | 06:54 |
| @kanzure | "In eukaryotes, the Cdt1-bound replicative helicase core MCM2-7 is loaded onto DNA by the ORC–Cdc6 ATPase to form a prereplicative complex (pre-RC) with an MCM2-7 double hexamer encircling DNA. Using purified components in the presence of ATP-γS, we have captured in vitro an intermediate in pre-RC assembly that contains a complex between the ORC–Cdc6 and Cdt1–MCM2-7 heteroheptamers called the OCCM. Cryo-EM studies of this 14-subunit ... | 06:55 |
| @kanzure | ... complex reveal that the two separate heptameric complexes are engaged extensively, with the ORC–Cdc6 N-terminal AAA+ domains latching onto the C-terminal AAA+ motor domains of the MCM2-7 hexamer. The conformation of ORC–Cdc6 undergoes a concerted change into a right-handed spiral with helical symmetry that is identical to that of the DNA double helix. The resulting ORC–Cdc6 helicase loader shows a notable structural similarity to ... | 06:55 |
| @kanzure | ... the replication factor C clamp loader, suggesting a conserved mechanism of action." | 06:55 |
| @kanzure | http://logs.readcube.com/s3bridge/s3bridge.html | 06:56 |
| @kanzure | http://logs.readcube.com/s3bridge/javascripts/jquery.ba-postmessage.js | 06:56 |
| @kanzure | http://logs.readcube.com/s3bridge/javascripts/jquery.ba-bbq.min.js | 06:56 |
| @kanzure | https://services.readcube.com/articles_api/GetArticleManifest?auth_token=02000090942c7cfe7342840321db05b7d08089b7c302fe019218e78d9b6d30303030303030302d303030302d303030302d303030302d303030303030303030303031&time=1373982869835&doi=10.1038%2Fnsmb.2629&s3=true | 06:57 |
| @kanzure | https://s3.amazonaws.com/objects.readcube.com/manifests/nature/52c123c64d0d2b435b724012a2db2f99deaf41b2689f3a0eb50a1fcc4eb68d06.xml?AWSAccessKeyId=1GA7H7KZR9DHKP03EMR2&Expires=1374069356&Signature=KNE3lVQpnAywT2F9vC5bj6UjggM%3D | 06:58 |
| @kanzure | https://services.readcube.com/articles_api/GetArticlePage/?auth_token=02000090942c7cfe7342840321db05b7d08089b7c302fe019218e78d9b6d30303030303030302d303030302d303030302d303030302d303030303030303030303031&hash=dc64a8faa0345df056ca7ba8d7554a791b45362c8336102acbcc9bf5058a73d1&page=1 | 06:58 |
| @kanzure | https://services.readcube.com/articles_api/GetArticlePage/?auth_token=02000090942c7cfe7342840321db05b7d08089b7c302fe019218e78d9b6d30303030303030302d303030302d303030302d303030302d303030303030303030303031&hash=dc64a8faa0345df056ca7ba8d7554a791b45362c8336102acbcc9bf5058a73d1&page=2 | 06:58 |
| @kanzure | POST https://analytics.readcube.com/metrics/create_session.json {"auth_token":"02000090942c7cfe7342840321db05b7d08089b7c302fe019218e78d9b6d30303030303030302d303030302d303030302d303030302d303030303030303030303031","data":{"full_text":true,"doi":"10.1038/nsmb.2629","preview":true,"referrer":"nature.com","issn":"1545-9993","platform":0,"referrer_type":0,"session_id":"CD76B701-8B45-A982-04BE-E7C2C736C589","epdf":true,"eissn":"1545-9985"}} | 06:59 |
| @kanzure | happy haxoring | 06:59 |
| @kanzure | access denied http://logs.readcube.com/heatmaps/ http://logs.readcube.com/ | 07:00 |
| @kanzure | hahah here's the assholes who made readcube: http://www.labtiva.com/ | 07:02 |
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| ParahSail1n | what is readcube | 07:05 |
| @kanzure | it's this evil pdf rental service that charges like $100/hour for reading | 07:05 |
| @kanzure | and somehow they convinced all the publishers that they are legit | 07:06 |
| @kanzure | elsevier and even nature are now embedding readcube javascript into all their pages | 07:08 |
| @kanzure | check out http://diyhpl.us/~bryan/papers2/paperbot/50a86f92583e8128b3d9361e58b1608b.txt (the nature link) | 07:08 |
| @kanzure | it has this: <script src="http://content.readcube.com/ping?doi=10.1038/nsmb.2629&format=js&last_modified=2013-07-14" type="text/javascript"></script> | 07:08 |
| @kanzure | which says /* ok */ actually.. that seems weird. and i changed it to http://content.readcube.com/ping?doi=10.1038/nsmb.2628&format=json and it says /* processing */ now. | 07:09 |
| @kanzure | i should probably write up a study of the change in javascript on different publisher sites based on paperbot failures | 07:11 |
| @kanzure | there's also this junk... http://onlinelibrarystatic.wiley.com/js/wol.readcube.js | 07:11 |
| @kanzure | i think it's hilarious that nature uses like 10-15 different jquery extensions. not even using requirejs. keep on rocking it... | 07:13 |
| @kanzure | oh wait, maybe it was deepdyve and not readcube. | 07:13 |
| @kanzure | http://www.nature.com/view/scripts/global.deepdyve.js | 07:14 |
| @kanzure | like: http://www.deepdyve.com/rental-link?fieldName=journal_doi&docId=10.1063/1.1582108&prog=normal&key=aip&affiliateId=aip&format=jsonp&callback=? | 07:16 |
| @kanzure | or http://www.deepdyve.com/doc-view?docId=10.1063/1.1582108&prog=normal&fieldName=journal_doi&affiliateId=aip | 07:16 |
| @kanzure | haha xss hole http://www.deepdyve.com/rental-link?fieldName=journal_doi&docId=10.1063/1.1582108&prog=normal&key=aip&affiliateId=aip%22`'&format=jsonp&callback=%3Cb%3Ehello%3C/b%3E | 07:17 |
| @kanzure | wonderful | 07:18 |
| @kanzure | ah there seems to be /brlcad/trunk/src/tclscripts/mged/bindings.tcl | 07:26 |
| @kanzure | oh that might be mouse control in brlcad. wtf. | 07:28 |
| @kanzure | 07:41 < starseeker> hmm. looking at it from that perspective, perhaps it doesn't make sense in any case for us to expose the brep/nurbs API as a top-level BRL-CAD api | 07:30 |
| @kanzure | welp. there are no bindings to brlcad at the moment. that needs to change. | 07:30 |
| @kanzure | paperbot: .title http://www.nature.com/nrd/journal/v11/n3/full/nrd3681.html | 07:42 |
| @kanzure | paperbot: http://www.nature.com/nrd/journal/v11/n3/full/nrd3681.html | 07:42 |
| paperbot | http://libgen.org/scimag/get.php?doi=10.1038%2Fnrd3681 | 07:42 |
| @kanzure | "The past 60 years have seen huge advances in many of the scientific, technological and managerial factors that should tend to raise the efficiency of commercial drug research and development (R&D). Yet the number of new drugs approved per billion US dollars spent on R&D has halved roughly every 9 years since 1950, falling around 80-fold in inflation-adjusted terms. There have been many proposed solutions to the problem of declining R&D ... | 07:43 |
| @kanzure | ... efficiency. However, their apparent lack of impact so far and the contrast between improving inputs and declining output in terms of the number of new drugs make it sensible to ask whether the underlying problems have been correctly diagnosed. Here, we discuss four factors that we consider to be primary causes, which we call the 'better than the Beatles' problem; the 'cautious regulator' problem; the 'throw money at it' tendency; and the ... | 07:43 |
| @kanzure | ... 'basic research–brute force' bias. Our aim is to provoke a more systematic analysis of the causes of the decline in R&D efficiency." | 07:43 |
| @kanzure | "1. $'s billions annual sales of new drugs added. Suggest the plots separate small molecule vs biotech drugs. 2. A much more subtle but, realistic set of events in which increased research spending actually slowed down the rate of new drug discovery. These events included a mass Pharma Industry move into 3 highly popular but relatively unproductive areas: Combinatorial Chemistry; HTS/U-HTS and Bioinformatics. These "new" approaches cost ... | 07:44 |
| @kanzure | ... lots of money and actually slowed down discovery. The so-called "Platform Technologies" proved to be less efficient than the classical medicinal chemist-directed synthesis approaches of earlier years. Turned out that the industry learned the hard way (overinvesting ) to "make haste...............slowly" . They are paying the price today by paying billions of dollars for acquisitions trying to fill their depleted pipelines back up. The ... | 07:44 |
| @kanzure | ... optimistic signs now are that NME approvals are on the rise back toward the 30's annually range. In 2011 there were 26 approvals (21 small molecule and 5 "biologicals- biotech"). And it appears that 2012 data will be into the low 30's." | 07:44 |
| gradstudentbot | If I was your endoplasmic reticulum, would you want me smooth or would you want me rough? | 07:45 |
| chido | gradstudentbot just made me spit out my coffee | 07:49 |
| gradstudentbot | Dropped my sample. | 07:49 |
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| @kanzure | gimme reasons to hate swig-wrapper again? i forgot. | 08:34 |
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| ThomasEgi | kanzure, how about starting with the name "swing-wrapper"? | 08:46 |
| @kanzure | i think it was swig-wrapper not swing-wrapper | 08:47 |
| ThomasEgi | oh.. well.. not that'd make the name any more attractive | 08:48 |
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| @kanzure | fenn: were you the one who disliked swig | 11:11 |
| ParahSailin | you binding brlcad? | 11:12 |
| @kanzure | not at the moment | 11:12 |
| @kanzure | but i'm just trying to remember why we hated swig | 11:12 |
| ParahSailin | all the python binding stuff is bad | 11:13 |
| ParahSailin | swig might be the least bad? | 11:13 |
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| ParahSailin | oh, brlcad is c, not c++, it might not be so miserable | 11:15 |
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| @kanzure | cython is reasonably okay to write | 11:23 |
| ParahSailin | yeah i've used it quite a bit | 11:24 |
| ParahSailin | people use swig if they | 11:25 |
| ParahSailin | 're trying to translate a lot of boilerplate c++ classes into python ones | 11:25 |
| ParahSailin | does cython have any automated transformation of code? | 11:26 |
| ParahSailin | huh http://wiki.cython.org/AutoPxd | 11:27 |
| ParahSailin | yeah i'd use cython then | 11:27 |
| @kanzure | problem with cython is that it's just python bindings | 11:39 |
| @kanzure | autopxd looks like C++ only? | 11:39 |
| @kanzure | oh, C/C++ | 11:39 |
| @kanzure | https://github.com/cournape/cython-codegen | 11:39 |
| @kanzure | "It requires gcc_xml and codegenlib from ctypeslib (apt get install python-ctypeslib)" | 11:39 |
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| @kanzure | alt+d is the greatest bash shortcut ever | 11:47 |
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| cpopell_ | Karl Guttag is a bro | 11:51 |
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| ParahSailin | oh, looks like significant parts of brlcad is c++ | 11:56 |
| ParahSailin | http://brlcad.org/wiki/NURBS_Intersections | 11:58 |
| ParahSailin | "BRL-CAD's support for these primitives is relatively recent, and while we can raytrace them we do not have the ability to perform operations such as surface/surface intersection calculations. " | 11:59 |
| nmz787 | kanzure: this says opensource http://www.genocad.org/ | 12:08 |
| ParahSailin | yeah thats part of the genome compiler i think | 12:09 |
| nmz787 | what??? | 12:11 |
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| @kanzure | ParahSailin: they are lying about that, they do have surface-surface. | 12:18 |
| ParahSailin | i guess thats from opennurbs then | 12:19 |
| @kanzure | oh definitely. opennurbs has some good parts that are open sourced that brlcad uses. | 12:19 |
| @kanzure | but all of the good shit (intersection stuff) is closed source and not available in opennurbs | 12:20 |
| @kanzure | and brlcad has been using opennurbs for ages. so those statements are accurate w.r.t their use of opennurbs. | 12:20 |
| @kanzure | hehe alt+d works in irssi. bwahaha. | 12:22 |
| @kanzure | iiiii iii iiii | 12:22 |
| @kanzure | oops. that didn't work. | 12:22 |
| ParahSailin | opennurbs intersection is closed? | 12:24 |
| @kanzure | correct, opennurbs is written by the same company that develops rhinocad and it's proprietary because they want rhino to be a thing you use | 12:26 |
| ParahSailin | what is https://github.com/louipc/opennurbs/blob/master/opennurbs_intersect.cpp | 12:28 |
| ParahSailin | oh i see, its not spline spline intersection | 12:28 |
| ParahSailin | paperbot: http://dx.doi.org/10.1016/0010-4485(84)90002-2 | 12:30 |
| gradstudentbot | Heh, undergrads. | 12:30 |
| paperbot | http://libgen.org/scimag1/10.1016/0010-4485%252884%252990002-2.pdf | 12:30 |
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| @kanzure | ParahSailin: if you have time.. trying to get brlcad bindings to work would be cool. especially for the nurbs stuff. | 12:42 |
| @kanzure | eventually i would like to have python and jvascript bindings (either seedjs or nodejs.. probably both), maybe jni bindings, and then some way to stuff it into golang or haskell. | 12:43 |
| ParahSailin | why bindings for all the things? | 12:46 |
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| @kanzure | ParahSailin: because i want to kill openscad, pythonocc, python-heekscad, freecad-python, and all the other terrible non-starters. you can't even use heekspython outside of heekscad. blah. | 12:53 |
| @kanzure | ParahSailin: also because i think that the current brlcad options are really lame. you can either use their mged editor script thing, or you can write in tk/tcl, or you can compile a program that #includes their libraries and static/dynamic links to it... lame. i'm not going to write a jet-engine.c file and compile it every time i want to render a new version! | 12:54 |
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| nmz787 | kanzure: so if i head down to sf i'm gonna try to meet openbiotech ppl | 13:21 |
| nmz787 | anyone know of anything else happening/worth visiting friday or the weekend? | 13:21 |
| @kanzure | juul is doing counter culture labs things | 13:21 |
| @kanzure | and then there is the synthetic biology class at biocurious | 13:22 |
| @kanzure | there's a party at synthego | 13:22 |
| @kanzure | probably something you could do with transcriptic | 13:22 |
| @kanzure | brownies: you might want to go to the synthego party just to amuse yourself at the biotech startup scene | 13:22 |
| brownies | kanzure: synthego? | 13:23 |
| @kanzure | just some random biotech startup, who cares | 13:23 |
| @kanzure | but i'm sure some people will be there | 13:23 |
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| nmz787 | yeah going down for that party | 13:33 |
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| brownies | when/where? | 13:36 |
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| @kanzure | brownies: 2013-07-20 5pm-late 990 La Mesa Drive, Portola Valley, CA http://www.google.com/url?q=http%3A%2F%2Fbit.ly%2F13xmXjk&sa=D&sntz=1&usg=AFQjCNFgLt09J3SkItgTUp-rY6m-8sKF7Q | 13:39 |
| @kanzure | erm i mean http://bit.ly/13xmXjk | 13:39 |
| @kanzure | erm i mean https://docs.google.com/forms/d/1f1NUOMUyyG8opYEjS6vb__4DrmovZj70nBUO8KFtZHc/viewform | 13:39 |
| @kanzure | god damn redirects | 13:39 |
| heath | https://gist.github.com/anonymous/1ea2f4906c7d6ae17682 | 13:42 |
| heath | grr | 13:42 |
| heath | .title | 13:42 |
| yoleaux | interesting stuff from Moyashimon | 13:42 |
| heath | i was watching these episodes while internet free | 13:43 |
| heath | according to google adwords, not a lot of people search for open source hardware | 13:45 |
| heath | or open source phone | 13:45 |
| @kanzure | nope | 13:45 |
| heath | open hardware summit gets about 4700 hits monthly | 13:45 |
| @kanzure | no that's queries, not clicks | 13:45 |
| heath | right | 13:46 |
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| delinquentme | paperbot, http://www.nature.com/nature/journal/v498/n7454/full/nature12217.html | 14:13 |
| paperbot | http://libgen.org/scimag/get.php?doi=10.1038%2Fnature12217 | 14:13 |
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| brownies | kanzure: portola valley? classy. but i wouldn't know anyone... might be weird. | 14:34 |
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| @kanzure | brownies: nmz787 | 14:35 |
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| @kanzure | or you can take Juul | 14:44 |
| Juul | take me out for ice cream? | 14:44 |
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| nmz787 | Juul: are you back in the Usa? | 14:51 |
| nmz787 | brownies: you got a polo and some slacks? | 14:51 |
| Juul | nmz787, i haven't left | 14:51 |
| nmz787 | !!! | 14:51 |
| nmz787 | ahh | 14:51 |
| Juul | though i would have liked to go to ohm, it seems it's not happening | 14:51 |
| nmz787 | so let's all party on some other dudes' bill | 14:51 |
| Juul | what kinda party? | 14:52 |
| nmz787 | series a funding for synthego | 14:52 |
| nmz787 | which supposedly is some kind of dna synth company | 14:52 |
| @kanzure | they might be lying of course | 14:52 |
| @kanzure | about synthesis | 14:52 |
| nmz787 | which is why we go party there | 14:52 |
| gradstudentbot | Oh great, my paper got accepted with no revisions. Nice. | 14:53 |
| @kanzure | they haven't presented any evidence that they do synthesis, but who knows | 14:53 |
| nmz787 | someone at transcriptic said they are facebook friends with someone there | 14:53 |
| nmz787 | who remarked on facebook a while ago something like "the science works!" | 14:53 |
| @kanzure | whatever | 14:54 |
| nmz787 | but even the person i talked with wasn't sure what that really meanth | 14:54 |
| nmz787 | meant | 14:54 |
| @kanzure | the echo chamber effect is pretty strong | 14:54 |
| @kanzure | you'll get used to it | 14:54 |
| Juul | what are they claiming they can do? | 14:56 |
| Juul | voice-activated augmented reality html5 cloud-based dna synthesis? | 14:56 |
| Juul | nmz787, when and where is this event? | 14:57 |
| nmz787 | saturday 5pm south-west bay | 14:58 |
| Juul | midpeninsula eh? | 14:58 |
| nmz787 | i think mid lower | 14:58 |
| Juul | i may or may not be in san diego | 14:58 |
| nmz787 | lower mid | 14:58 |
| Juul | wait, wasn't there another event at hacker dojo | 14:59 |
| Juul | oh yeah, the BACH roundtable | 14:59 |
| @fenn | we all sit around a table getting drunk and singing bach rounds | 15:00 |
| Juul | so i guess i'm in the same area at the same time | 15:00 |
| Juul | i could come by and have a free beer and pretend i'm a startup person? fun times? | 15:01 |
| brownies | nmz787: there's a dress code? | 15:06 |
| brownies | perhaps you don't know how startup folks dress... | 15:06 |
| brownies | a polo and slacks is the SF startup equivalent of black tie | 15:06 |
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| heath | hrm, some guys from SF are trying to create a js web framework based on functional programming principles | 15:09 |
| heath | functional programming languages: 4,420 queries | 15:09 |
| heath | not sure how they plan on monetizing thie venture | 15:09 |
| heath | this* | 15:09 |
| heath | meteor went the PAAS route | 15:09 |
| heath | and are supposedly having problems | 15:10 |
| heath | $12 million in funding isn't terrible | 15:10 |
| heath | that was a few years ago | 15:10 |
| heath | surely they haven't went through all of that by now | 15:10 |
| nmz787 | brownies: you said classy! | 15:10 |
| heath | fenn: where are you working? | 15:13 |
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| @fenn | heath: i'm not working atm, half-assedly looking for a job | 15:22 |
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| @kanzure | Juul: if you are in san diego then you should visit yashgaroth and jonathan__________ | 15:23 |
| heath | fenn: what kind of job are you looking for? | 15:23 |
| @fenn | the tail is how you know he's a super-saiyan | 15:23 |
| Juul | kanzure, thanks! | 15:23 |
| @kanzure | heath: is it meteorjs? | 15:23 |
| heath | that's the one | 15:24 |
| heath | meteor.com | 15:24 |
| @kanzure | "trying".. i'm pretty sure they already wrote it. | 15:24 |
| @kanzure | or they are lying to you | 15:24 |
| @fenn | legions of fanboys can't be wrong | 15:24 |
| @kanzure | didn't you live with the meteorjs person | 15:24 |
| Juul | http://kanako.dk/clients/fun/WOOORRK!/ | 15:24 |
| @fenn | yeah, i did. meteor actually looks pretty cool, but i don't know what i'd use it for | 15:25 |
| heath | kanzure: the functional programming centric web framework isn't meteor, it hasn't been built yet | 15:25 |
| heath | i have issues with it | 15:25 |
| @kanzure | i don't know why i would want to use meteor either. why can't i just use angularjs/backbonejs/other standard components. | 15:26 |
| @kanzure | i guess they are trying to monetize the all-in-one package. since every javascript programmer seems to be an idiot that ignores their own standards. ugh. | 15:26 |
| heath | https://gist.github.com/switz/4458423 | 15:27 |
| @kanzure | heath: hey if you want to do helpful javascript things, help me write a commonjs implementation for gnome seedjs | 15:27 |
| heath | the original of that rant is gone :| | 15:28 |
| @kanzure | wtf "Meteor doesn’t use NPM" | 15:28 |
| @kanzure | why would they choose to do that | 15:28 |
| heath | they have since fixed this | 15:28 |
| heath | and there is a way to get a RESTful api | 15:28 |
| @kanzure | i don't care about the restful api shit, thta can be included from a node module on npm | 15:28 |
| @kanzure | if you don't support package.json, that's shooting yourself in the foot. you are basically committing yourself to perpetual js spaghetti. | 15:29 |
| heath | when i was looking at it, i was planning an app that would run on the phone natively, converting a meteor app to something that can be ran on a phone is a nightmare | 15:29 |
| @kanzure | phonegap/cordova. | 15:29 |
| @kanzure | cordova has recently added npm support for managing the javascript-side of things | 15:29 |
| heath | if you go the express + angular route, then you can just cut out your express portion and let phonegap convert it | 15:29 |
| @kanzure | that's not the right way to do phonegap | 15:30 |
| @kanzure | oh, i see what you mean. not over http. | 15:30 |
| @kanzure | but no, you don't need to "cut out".. you should have a library that you call into to access your core js. | 15:30 |
| @kanzure | this is just basic design and separatoin of components :( | 15:30 |
| @kanzure | *separation | 15:31 |
| @kanzure | blah. rant over. | 15:31 |
| @fenn | i love how every language develops its own set of opaquely-named libraries that all do more or less the same thing | 15:31 |
| @kanzure | import os | 15:33 |
| @kanzure | i thought that was the point. you get bindings to all the system libraries. | 15:33 |
| @kanzure | gnome seed is pretty nice because it takes all of gtk's system bindings (gobject) and dumps them into javascript. or rather, it is just a javascript interoperability layer. | 15:34 |
| @fenn | can i "import os" in node? | 15:34 |
| chris_99 | whats the gnome js for? | 15:34 |
| @kanzure | you can do it in gnome seedjs, which is like node except jsc instead of v8 | 15:34 |
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| @kanzure | and gnome seedjs suffers from less attention than node. nobody has written require() for gnome seed. | 15:34 |
| @fenn | why the hell does require() even need to be written | 15:35 |
| @kanzure | http://commonjs.org/ | 15:35 |
| @kanzure | there's a few other common api stuff that has to be implemented | 15:35 |
| @kanzure | and then the vast majority of javascript written for browsers and nodejs will just "magically work" | 15:35 |
| @kanzure | but instead gnome seed implemented this crazy custom thing called "imports" | 15:35 |
| @kanzure | so you type "imports.gi.os" to get "os".. and "imports.myfile" to get "myfile.js". | 15:36 |
| @kanzure | naturally, none of the stuff on http://npmjs.org/ uses "imports.myfile". | 15:36 |
| @kanzure | but the advantage of gnome seed is that you have all of the gnome code (including bindings to webkitgtk+, which can be compiled from webkit.git whenever you please) | 15:37 |
| @fenn | but someone can just make a wrapper for imports, right? | 15:38 |
| @fenn | or require, or whatever the other way of doing it is | 15:38 |
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| @kanzure | fenn: yeah, i was doing that, but it requires a change to seed's C code | 15:39 |
| @kanzure | fenn: there needs to be a way to pass in a string and get it compiled (i am hesitant to use eval()) | 15:40 |
| @kanzure | this was my attempt but it didn't work https://github.com/kanzure/seed/commit/d5bcaea5db544619f1ec1b89e17126d5eee19734 | 15:40 |
| @fenn | because imports is hardcoded? (in c) | 15:40 |
| @kanzure | yes | 15:40 |
| @kanzure | the problem is that i couldn't get my function exposed in the global context or w/e | 15:40 |
| @kanzure | i was very confused | 15:40 |
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| @fenn | didn't we learn this lesson already and decide to use pypy | 15:40 |
| @kanzure | this is how phantomjs does it: https://github.com/ariya/phantomjs/blob/master/src/phantom.cpp#L362 see loadModule | 15:41 |
| chris_99 | so does seedjs require gnome to be installed in full? | 15:41 |
| @kanzure | no, just some core components | 15:41 |
| @fenn | chris_99: keep in mind there's a huge difference between "gnome" and "gtk" | 15:41 |
| @fenn | gtk is actually "gimp toolkit" fwiw | 15:42 |
| chris_99 | indeed fenn | 15:42 |
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| @kanzure | so, i want this to replace phantomjs | 15:42 |
| @kanzure | phantomjs vendorizes qt 4.8 and qtwebkit from qt 4.8.. so you can't just get a new webkit version whenever you want | 15:43 |
| @kanzure | and phantomjs doesn't even make sense anyway; why not just write javascript that uses the webkit api. | 15:43 |
| @kanzure | the webkitgtk+ gobject bindings actually let you access html dom stuff directly | 15:43 |
| @fenn | maybe they couldn't do everything they wanted with the api | 15:44 |
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| @fenn | (the obvious workaround there would be to add whatever functionality you need to the api) | 15:44 |
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| @kanzure | yes that's what my commit was | 15:46 |
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| @fenn | i meant change webkit's API | 15:49 |
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| brownies | nmz787: heh. | 15:51 |
| @fenn | so, i thought js was interpreted. is seed doing something totally different? | 15:51 |
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| @fenn | huh, guess i was wrong. "V8 compiles JavaScript to native machine code (IA-32, x86-64, ARM, or MIPS CPUs)[3][6] before executing it, instead of more traditional techniques such as executing bytecode or interpreting it. The compiled code is additionally optimized (and re-optimized) dynamically at runtime, based on heuristics of the code's execution profile." | 15:56 |
| heath | fun fact, try/catch statements aren't optimized as of old information from ~4months ago | 15:57 |
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| @kanzure | fenn: seed is compiled wrapping/binaries between javascriptcore and gnome library stuff. | 16:04 |
| @kanzure | i think maybe eval is sufficient... maybe. | 16:22 |
| @kanzure | not enough time in the day | 16:22 |
| @kanzure | that seedjs compile() stuff needs to be fixed | 16:22 |
| @kanzure | and brlcad really needs bindings | 16:22 |
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| heath | wish my phone didn't break this morning, there's a deer 20 feet directly behind my computer screen grazing in my front yard | 16:28 |
| heath | it's so cute | 16:28 |
| @bkero | kill it and eat it | 16:28 |
| heath | it's eating from some bushes of mine :) | 16:28 |
| gradstudentbot | I think our octopus might be smarter than me. | 16:30 |
| heath | fuck, it just shit on my sidewalk | 16:36 |
| heath | son of a | 16:36 |
| heath | ok, those flowers were expensive | 16:36 |
| heath | god dammit | 16:36 |
| * heath walks outside for a bit | 16:36 | |
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| nmz787 | so what are the selected linux distros mentioned to support secure boot? http://en.wikipedia.org/wiki/Unified_Extensible_Firmware_Interface#Secure_boot | 17:51 |
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| delinquentme | gradstudentbot, whats your dissertation focus? | 18:06 |
| gradstudentbot | No no no no! Use your key commands! | 18:06 |
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| jonathan_ | """The main point of the video that I have been shooting at BTnB has been so that I can perform a microsociological analysis on how people come together to launch and sustain a biohacking space. """ WHO LET THAT HUMANITIES MAJOR IN HERE ? | 18:15 |
| @kanzure | "sustain" | 18:19 |
| jonathan_ | max | 18:22 |
| jonathan_ | well back in the day there were (still are) a bunch of fruitloops bent on being "archeologists of digital culture" wth that means | 18:22 |
| jonathan_ | ""It is perfectly legitimate, I should add, for anyone including myself to observe public gatherings-- "" | 18:24 |
| jonathan_ | city building != public gathering place? | 18:24 |
| jonathan_ | or clarification.. city building leased to private entity? | 18:24 |
| @kanzure | i think journos don't realize that when they walk in and claim things are impossible for them to understand, it's really insulting | 18:29 |
| @kanzure | what, i didn't work hard to do what i do? | 18:30 |
| jonathan_ | anywayz i think I got a biz opp just now for kombucha of all friggin things | 18:30 |
| @kanzure | you think i strolled out of my mom's vagina and magically knew this shit? | 18:30 |
| jonathan_ | yea | 18:30 |
| jonathan_ | geez kids these days have it so easy | 18:31 |
| @kanzure | scrum was originally "get the fuck out of their way" ? https://news.ycombinator.com/item?id=6054560 | 18:31 |
| jonathan_ | everything you want to know is on google or wikipedia for f' sake | 18:31 |
| jonathan_ | yes | 18:31 |
| @kanzure | i'm pretty sure that's not how it's practiced | 18:32 |
| @kanzure | agile scrum etc | 18:32 |
| jonathan_ | just like "hacking" used to be about "do cool things for fun and ego" not "to protect potential profit streams I don't realize now but 15 years from now by artificial license lockups" | 18:33 |
| jonathan_ | well nowadays people just say "we're doing agile" because it sounds hip, flavor of the month | 18:34 |
| jonathan_ | even though what they really mean is: "we have no plan and no capability to plan so basically it's just chaos and nothing is written down because no one is talented enough to write things down" | 18:34 |
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| @kanzure | jonathan_: people act like i'm talented just for being able to type | 18:37 |
| jonathan_ | max dude this sangria is some mighty fine stuff | 18:37 |
| jonathan_ | yea! and clearly they are right! | 18:38 |
| jonathan_ | cause most people cant type.. hell I work with 40 people regularly and not one of them can take meeting minutes worth a damn | 18:38 |
| @kanzure | all of the meetings i go to end up with full transcripts (typed by me) | 18:39 |
| @kanzure | i am also able to coherently say relevant things, but unfortunately i don't type the things i say. this is probably a mistake. | 18:39 |
| jonathan_ | even the project manager new fancy hire guy told me one time, "I can't be expected to take meeting notes while running the meeting" | 18:39 |
| @kanzure | hahah | 18:39 |
| jonathan_ | I told him what I thought of that idea | 18:39 |
| @kanzure | you should just bring me in i guess. i could also do software things i guess. | 18:39 |
| jonathan_ | you dont type the things you say. that is an odd statement | 18:39 |
| @kanzure | you have 200 MB of RAM, right? so 8 bytes per character is no problem, right? | 18:40 |
| @kanzure | well, i mean, when i'm in a meeting | 18:40 |
| @kanzure | and i'm typing a transcript, and i say something, it's hard for me to both type it out and also talk at the same time | 18:40 |
| jonathan_ | I told them they better hire a transcriptionist, they arent that expensive | 18:40 |
| @kanzure | a good one? | 18:40 |
| jonathan_ | oh I think you should just practice that it is quite natural | 18:40 |
| @kanzure | like, even tv caption people seem to miss everything | 18:40 |
| jonathan_ | no, it doesnt have to be a good transcriptionist, tech meetings are slow overall, who cares about typos, just collect the main content / theme / agreements | 18:41 |
| @kanzure | haha my transcripts would blow you away | 18:41 |
| @kanzure | i catch everything in a meeting | 18:41 |
| @kanzure | and then at the end i also have a fancypants todo list | 18:41 |
| @kanzure | that represents what everyone actually agreed to | 18:41 |
| jonathan_ | I think I went off on a rant on the project manager "well let me see I ran the last meeting and I typed meeting minutes and I ran the bug tracking system at the same time, so I do it, you can too" | 18:41 |
| jonathan_ | anywayz I'm taking my sangria to the sunset brb | 18:42 |
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| gradstudentbot | I forgot to make a control group. | 18:44 |
| heath | i didn't find agile scrum to be effective at getting much done | 18:47 |
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| jonathan_ | need a tight lead. it works well. | 19:04 |
| jonathan_ | well ok i've been successful with something I guess other people call agile xp scrum when in fact it is actually: todo list review, revise & reprioritize, dont interrupt the devs and answer all outstanding q's definitively so devs dont have to stop & think (including myself) | 19:06 |
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| heath | i really appreciate python's consistent styling | 19:15 |
| jonathan_ | everyone always groans at python's whitespace requirements at first | 19:17 |
| @kanzure | i don't | 19:18 |
| jonathan_ | at first? | 19:18 |
| jonathan_ | like "omg wtf is this" | 19:18 |
| @kanzure | just don't mix tabs and whitespace in my repos and i'm happy | 19:19 |
| jonathan_ | like "its enforcing ws how lame & retarded" | 19:19 |
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| jonathan_ | after the first week or so, then people like it | 19:20 |
| jonathan_ | the ws thing is why I avoided python in early versions too | 19:20 |
| gradstudentbot | Nobody has tried this before. | 19:21 |
| jonathan_ | linkedin is getting scary. dunno why ex gf's pop up there. it's not good. | 19:21 |
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| jonathan_ | conductive gold nanoparticles + antibodies = ? | 19:26 |
| ParahSail1n | lasers | 19:31 |
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| jonathan_ | NO | 19:37 |
| * heath misses his third monitor | 19:39 | |
| yashgaroth | doesn't linkedin harvest email info from people dumb enough to let them | 19:39 |
| jonathan_ | 10nm gold nanoparticle has conductivity of 2.5e-2 across f=(10hz,10e5hz) fyi | 19:40 |
| jonathan_ | "measured conductivity values increased with the decreasing of gold nanoparticle size" any reasons for why this might be? | 19:41 |
| jonathan_ | oh constant concentration hm | 19:42 |
| ParahSail1n | in suspension? | 19:42 |
| jonathan_ | max you callin my ex gf's dumb? | 19:42 |
| jonathan_ | "aqueous solution" hm | 19:43 |
| yashgaroth | to give linkedin the password to their email? also what article are you referencing here | 19:43 |
| ParahSail1n | its well known that the main mechanism of electron conduction in those sorts of situations is tunneling | 19:43 |
| ParahSail1n | the more small particles, the less the average distance between them, so tunneling goes faster | 19:43 |
| jonathan_ | so lemme see all we's haves to dos is increase nanoparticle uptake by cancer cells and then apply the electrodes, ZAP FRY | 19:44 |
| jonathan_ | I guess I naively supposed that the nanoparticles would behave like mini capacitor plates. apparently not | 19:45 |
| jonathan_ | tunneling, hm I'll check that out later | 19:46 |
| jonathan_ | this is from DOI: 10.5897/IJPS11.1073 | 19:46 |
| ParahSail1n | paperbot, http://dx.doi.org/10.5897/IJPS11.1073 | 19:50 |
| paperbot | http://diyhpl.us/~bryan/papers2/paperbot/547eb71fe202382044cedd701310228c.txt | 19:50 |
| ParahSail1n | tunneling is actually how the electron transport chain works | 19:51 |
| yashgaroth | http://www.academicjournals.org/ijps/pdf/pdf2011/9Oct/Abdelhalim%20et%20al.pdf | 19:51 |
| ParahSail1n | as in, mitochondria and chloroplast | 19:51 |
| jonathan_ | oh really, hm | 19:52 |
| ParahSail1n | paperbot, http://www.pnas.org/content/107/45/19157.full | 19:53 |
| paperbot | http://libgen.org/scimag/get.php?doi=10.1073%2Fpnas.1009181107 | 19:53 |
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| cpopell | Sup | 20:01 |
| jonathan_ | ""Brian Murray The Photonics Group I'm a technical recruiter and I have 2 mid level firmware engineering openings with one of my clients and the location is outside of Philadelphia, PA. " | 20:07 |
| jonathan_ | "In 1986, SCRUM consisted of choosing an elite team of experts, throwing them into a room, and telling them to solve a problem with seemingly impossible goals." --> I thought this was SKUNKWORKS.. not SCRUM | 20:11 |
| ParahSail1n | i forget what the tech requirement for a skunkworks is | 20:14 |
| jonathan_ | lol is that a joke | 20:17 |
| jonathan_ | skunkworks operate w/o requirements ;-D | 20:17 |
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| jonathan_ | the problem is that non-smart devs cant handle agile/scrum/skunk/xp whatever you might want to call it. they need a stone tablet with spec written on it and their job & only job is to build according to that spec w/o deviation. otherwise they will get lost. | 20:19 |
| jonathan_ | umm maybe it's called "critical thinking" i dunno | 20:19 |
| ParahSail1n | advanced subatomic theory in think lets you build skunkworks, but its not really worth building them in very many colony bases | 20:20 |
| jonathan_ | uhh you lost me | 20:21 |
| jonathan_ | gradstudentbot did you understand that? | 20:21 |
| gradstudentbot | Can I get Saturday off? | 20:21 |
| jonathan_ | see | 20:21 |
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| jonathan_ | "" Dr Poulter's first experience with the Church's actions online came in the early 90s when he was browsing a newsgroup called alt.religion.scientology, a place where critics and ex-members were posting information on the Church. "The reaction from the Church of Scientology was that it went really beserk," recalls Dr Poulter. With the help of local authorities, houses belonging to newsgroup users across the US were raided, with | 21:11 |
| jonathan_ | computer equipment being seized for weeks on end. "The days of the internet as a cozy, private, intellectual cocktail party are over," technology magazine Wired prophetically declared in 1995." http://www.bbc.co.uk/news/technology-23273109 How Scientology changed the internet | 21:11 |
| gradstudentbot | Friends don't let friends go to super school. | 21:13 |
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| jonathan_ | paperbot http://link.springer.com/article/10.1007/s00897990367a | 22:08 |
| paperbot | http://libgen.org/scimag2/10.1007/s00897990367a.pdf | 22:08 |
| jonathan_ | paperbot http://www.sciencedirect.com/science/article/pii/S0378874100001616 | 22:11 |
| paperbot | http://libgen.org/scimag4/10.1016/S0378-8741%252800%252900161-6.pdf | 22:11 |
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| jonathan_ | paperbot i luv u, oh no no, i luv u more, oh oh no no, i luv you most! | 22:12 |
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| jonathan_ | ""Kiera Wilmot, 16, was arrested in April and sent to an alternative school after she mixed household products in a water bottle, causing a small explosion on the grounds of Bartow High School. The felony charges were dropped last month, and now Wilmot’s lawyer says the youth will be allowed to return to Bartow in the fall, the Orlando Sentinel reports. Wilmot, who has served a 10-day suspension, says she is eager to return t | 23:35 |
| jonathan_ | Bartow, the story reports. She says she brought the water bottle and products to school to show a science teacher for a possible class project. She says friends coaxed her into mixing the items, however, before the school day began.""" | 23:35 |
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| jonathan_ | paperbot http://pubs.acs.org/doi/pdfplus/10.1021/ed3002545 | 23:49 |
| paperbot | http://libgen.org/scimag5/10.1021/ed3002545.pdf | 23:49 |
| jonathan_ | paperbot http://pubs.acs.org/doi/pdfplus/10.1021/ed3002557 | 23:50 |
| paperbot | http://libgen.org/scimag5/10.1021/ed3002557.pdf | 23:51 |
| jonathan_ | paperbot http://pubs.acs.org/doi/pdfplus/10.1021/ed300256a | 23:51 |
| paperbot | http://libgen.org/scimag5/10.1021/ed300256a.pdf | 23:51 |
| Adifex | For every case like that, I wonder how many there are that don't make the news | 23:52 |
| Adifex | I'm advising a high school student who wants to build a fusion reactor. If a water bottle of chemicals is worth felony charges, I wonder what a fusion reactor is worth. | 23:54 |
| jonathan_ | paperbot http://pubs.acs.org/doi/pdf/10.1021/ed300396x | 23:54 |
| paperbot | http://libgen.org/scimag5/10.1021/ed300396x.pdf | 23:54 |
| jonathan_ | yea | 23:55 |
| jonathan_ | hopefully he doesnt do it anywhere near a school ground where laws can be very very strict | 23:55 |
| jonathan_ | many of those laws are due to the u.s. war on drugs | 23:55 |
| Adifex | then again, a small fusion reactor is probably safer than a bunch of household chemicals | 23:55 |
| gradstudentbot | If I was your endoplasmic reticulum, would you want me smooth or would you want me rough? | 23:55 |
| jonathan_ | Developing Tools for Undergraduate Spectroscopy: An Inexpensive Visible Light Spectrometer DOI: 10.1021/ed300396x "The design and implementation of an inexpensive, high-resolution Littrow-type visible light spectrometer is presented. The instrument is built from low-cost materials and interfaced with the program RSpec for real-time spectral analysis, making it useful for classroom and laboratory exercises. Using a diffractio | 23:56 |
| jonathan_ | grating ruled at 1200 lines/mm and blazed in the first order, the spectrometer was found to have a resolution (R = λ/Δλ) of 7500 (0.07 nm) at 525 nm allowing for detailed spectroscopic experiments such as an analysis of the iodine vibronic spectrum or multiplet line splitting in the solar spectrum. The simple design of the spectrometer makes it possible to exchange gratings of different lines/mm easily." | 23:56 |
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| jonathan_ | holy electron | 23:58 |
| jonathan_ | they call it "low cost" and it has a $200 camera, $105 diffration grating, and $50 at least of optics | 23:59 |
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