2013-11-14.log

--- Log opened Thu Nov 14 00:00:24 2013
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@archelsAuthor=(Lee, S)05:33
@archelsResults: Approximately 149,69305:33
@archelssemantic web, where art thou05:33
EnLilaSkoCan anyone help me understand ligand binding assay?05:35
EnLilaSkoHow they do it that is05:36
EnLilaSkoOr ho, this seems to explain it easy - http://www.htrf.com/sites/default/files/htrf/products/ligand-binding-assay-description.gif05:37
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foucistthe first step of transhumanism: http://www.youtube.com/watch?v=M7FIvfx5J1007:17
foucistit all starts with JCV07:18
foucistD07:18
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entelechiosare the aaron schwartz jstor leaks searchable somewhere or do i gotta download all 33gigs? i'm in a country with shoddy internet service08:06
entelechiosbut i'd like to see if an article is in there that i'd like to read08:07
ParahSai1inpaperbot: http://pubs.acs.org/doi/pdf/10.1021/es401288x08:10
paperbothttp://diyhpl.us/~bryan/papers2/paperbot/2ab115be13e52bbb9fbd78ecddd0bd19.pdf08:10
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rkoshttp://www.wired.com/wiredscience/2013/11/christof-koch-panpsychism-consciousness/08:31
ParahSai1inlol we dont do -psych- or consciousness here08:31
ParahSai1ini think they do in ##lesswrong08:31
rkossurely theres something useful in it08:34
ParahSai1inyou'd like ##lesswrong, stop fighting it08:34
eudoxiait's just #lesswrong08:35
eudoxiaguess they don't respect Freenode's policies like we do08:35
rkosmmkay08:37
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kanzureentelechios: those 33 gigs are not the aaronsw jstor leaks. that was someone else.09:45
entelechiosyea i realized that soon after searching around earlier this morning heh09:50
entelechiosmy memory can be fuzzy09:51
kanzure"You are incorrect. This circuit can potentially apply unsafe currents across the patient. A standard medical biopotential measurement circuit will have single-point failure protection to prevent conditions like this. This is required by standards like EC11, EC13, and 60601. Those systems are extremely safe."09:51
kanzure"Most hobbyist designs, like the one in this article, do not have such protection. Indeed, for this particular circuit, a simple static discharge, as might happen when you're applying the electrodes after walking over carpet, can fry the input amplifier, connecting it to the power rails. ESD (and, indeed, defibrillation -- which is about a thousand times more energy than ESD) protection would be present and required in any medical ...09:51
kanzure... biopotential amplifier, even unrelated to the single-point protection described above."09:51
kanzure"'ve seen dozens of circuits for home EEG/ECG/EMG. Almost all of them, including this one, are a deathtrap. They will work okay most of the time. At some point, someone's going to kill themselves."09:51
entelechiosi'm just going to put it on my list of crap to hope is at the local uni next time i come around to a day off09:51
kanzure"If the ESD failure happens to short out to power rails, your current will be your power rails divided by your electrode impedance. This distribution is described in EC11/EC13 (although electrode technology has improved since the days when those tests were done, so impedance is even lower). Even with the ancient electrodes in EC11/EC13, you would get unsafe currents some of the time. With modern electrodes, you would get unsafe currents much ...09:51
kanzure... of the time."09:51
entelechioswow that sounds sketchy09:52
entelechioshaving some mad scientist dumbass fry your brain by accident09:52
entelechiosthanks for the notification09:52
kanzurewell, no, the more important part of that quote is EC11, EC13, and 6060109:53
kanzurethe risk aversion is bullshit and ignorable09:53
foucist"deathtrap" sounds like a serious exaggeration09:53
foucistyeah09:53
foucistFUD09:53
foucistignore FUD!09:53
kanzurebut the standards are probably useful09:53
foucistunless designed by a committee09:54
kanzurenot all committee standards are useless09:55
kanzureespecially if you've never designed a circuit like that before09:55
foucistgenerate a human competitive circuit using genetic/evolutionary computation instead! :P09:57
ThomasEgithere are a number of worst-case failures one has to take care about when designing circuits like that. but if you know what you are doing it's not too much of a problem. many people however, have no clue what they do.09:57
foucistwww.human-competitive.org09:57
kanzureThomasEgi: sorry, can you clarify which situation is not a problem? (1) designing the additional safety features, or (2) not having them09:58
kanzureThomasEgi: your statement seems ambiguous09:58
ThomasEgidesigning a safe circuit09:58
kanzurewhat sort of safety features would you want in a tdcs setup?10:00
foucistwell all you really need is "don't electrocute humans"10:00
foucistthat's just 1 safety feature10:01
kanzureunfortunately i believe that is the function of tdcs10:01
ThomasEgiesd protection, transient protection, a fast acting electronic current limiter, optional a slower mechanism to cut the lines, like a fuse, a galvanically non-coupled supply..10:01
ParahSai1iner yeah, what exactly are people doing tdcs for10:02
ThomasEgimost tdcs designs i saw so far were like a 2 9V batteries and a resistor, some very few actually contained a current regulator.10:02
ThomasEgiboth fail pretty much every single "security" aspect10:02
chris_99that's scary10:03
foucistcan you kill someone with 2 9V batteries?10:03
foucistwell i suppose so10:03
ParahSai1inin the right place10:03
ThomasEgiyou can kill someone with 1.5V battery10:03
foucistjust need transformer to get hte amperage10:03
chris_99no you don't10:03
ThomasEgiyou don't need amperage or high voltages if it's in the wrong spot10:03
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ThomasEgia few nanoAmps and a few hundret millivolts are enough to make your heart stop if you have the wires in the wrong place10:04
foucistah10:05
ThomasEgiusualy. voltages below 50V are not much of a deal since the skin has a high enough resistance to prevent any major current flow and thus bad effects.10:05
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ThomasEgibut as soon as you drag electrode is, designed to lower that resistance..10:06
ThomasEgithings require more attention.10:06
foucisthmm, this is DC as well10:07
foucistAC is safer is it not?10:07
foucisthow about AC-based tdcs?10:07
foucistheh10:07
foucisttesla ftw10:07
ThomasEgitotaly depends on the parameters.10:08
ThomasEgiunless you use very high frequencies.. AC is not much safer10:08
ThomasEgiin some situations. it can be even worse.10:08
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kanzurethere should be a moon bounce inflation company that lets kids design moon bounces with 3d modeling and then lets them bounce in them12:34
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ParahSai1inand by kids you mean you12:36
foucisthmm, not a bad idea, but how expensive are moon bounce inflations?12:37
foucistnot counting the blowers (you can rent that)12:37
foucistthough blowers are typically a hundred bucks a day to rent .. hmm12:37
chris_99moon bounce?12:37
kanzureit's just a plastic manifold that you blow air into12:37
foucistchris_99: those inflateable "buildings" that you crawl into and jump up and down inside them12:37
kanzurewell, not plastic actually. i don't know what the material is.12:37
chris_99ah cool, i was confused as the only moon bounce i've heard of is bouncing radio waves off the moon heh12:38
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delinquentmeAnyone know of good published research on the interactions of cryoed cells reintegrating within tissues from the same individual?12:49
poppingtonichey bkero12:53
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ParahSai1inscholar.google.com13:01
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bkeropoppingtonic: Hi! What's up?14:55
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poppingtonicbkero: might be useful when you arrive. I've been here, great place. www.tripadvisor.com/Hotel_Review-g294207-d754110-Reviews-Kikuyu_Lodge_Hotel_Safaris-Nairobi.html16:12
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bkeropoppingtonic: Looks nice! If I have some days in Nairobi I'd like to stay there.16:16
poppingtoniccool, I'll introduce you to the owners when you come in!16:20
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poppingtonicpaperbot, http://dx.doi.org/10.1038/nature.2013.1219016:26
paperbothttp://diyhpl.us/~bryan/papers2/paperbot/7f92b807da17bf7e689c483390933981.txt16:26
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bkeropoppingtonic: Hah! What more could I ask for? That's awesome!!16:33
bkeroI'm booking all my plane tickets, etc, now.16:37
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poppingtonicExcellent.16:41
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foucistkanzure: jamesrobey.com/moon-bouncers.xls from www.real-inflatables.com18:28
foucistlooks like it can cost anywhere from $600-$2000 etc heh18:28
kanzurethat's not bad18:31
foucistit's probably a viable biz idea.. almost like edutainment18:32
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--- Log closed Fri Nov 15 00:00:25 2013

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