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| Lemminkainen | peparbut: https://www.cell.com/abstract/S0092-8674%2813%2901521-3 | 01:20 |
|---|---|---|
| Lemminkainen | paperbot: https://www.cell.com/abstract/S0092-8674%2813%2901521-3 | 01:20 |
| paperbot | http://libgen.org/scimag/get.php?doi=10.1016%2Fj.cell.2013.11.037 | 01:20 |
| Lemminkainen | kanzure that's all part of the IND | 01:20 |
| Lemminkainen | the initial Phase 1AB tends to run 800 pages | 01:21 |
| Lemminkainen | by the time it hits Phase IV trials the DMFs and INDs generally hit 15,000 pages | 01:21 |
| Lemminkainen | the composition of which tends to run companies about $250K in man-hours alone | 01:21 |
| @kanzure | what else? | 01:22 |
| Lemminkainen | and the "can I make my cat glow" FAQ is actually a good idea | 01:22 |
| Lemminkainen | I may record some with Dreg | 01:23 |
| Lemminkainen | what else? quite a bit in legal fees, clinical administrators, and insurance along the way | 01:23 |
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| Lemminkainen | along with patient care and renumeration, data processing costs, and the actual research costs of conducting biopsies and other medical tests | 01:24 |
| @kanzure | the glowing cat stuff is just really annoying, creating a FAQ will attract more of those people | 01:24 |
| Lemminkainen | and then they'll ask more intelligent questions | 01:24 |
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| @kanzure | drewbug: did you say you're in sf? | 08:42 |
| drewbug | I live in Harrisburg, PA, but I'll be in SF from Thursday to Sunday. | 08:43 |
| @kanzure | oh well. i'm leaving tomorrow. | 08:45 |
| drewbug | Aww. Darn. | 08:45 |
| drewbug | Where do you normally reside? | 08:45 |
| @kanzure | austin | 08:46 |
| drewbug | Cool. If I'm ever in the area, I'd love to visit. | 08:47 |
| drewbug | And if you're ever in good ole Pennsylvania, feel free to stop by for however long you'd like. | 08:47 |
| gradstudentbot | That's not really surprising since they did it ex vivo. | 08:47 |
| @kanzure | agreed w/ gradstudentbot on this one | 08:51 |
| gradstudentbot | I lost my pipette. | 08:51 |
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| @kanzure | "New Bio DIY space to be open @ Addis Ababa Ethiopia" | 09:22 |
| @kanzure | "Hello I am Apneet Aseffa I am very much interest on DIY Bio , and want to have branch at Ethiopia. basically there are a lot of masters, PHD graduates and also importantly high school students too interested on bio tech hacking i want to create this DIYBio Space in my area, before this idea off-course we worked on DIY Artificial intelligence Robotics lab. We just want to expand more on bio hacking too" | 09:23 |
| drewbug | Fun. | 09:26 |
| gradstudentbot | Who the hell stole my pipette? | 09:27 |
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| FourFire | kanzure, is gradstudentbot's random science related outbursts helpful to the channel? | 09:31 |
| gradstudentbot | Who has the latest version of the paper? | 09:31 |
| drewbug | Morale booster. | 09:32 |
| @kanzure | FourFire: no | 09:34 |
| @kanzure | FourFire: but nobody has proposed banning him yet | 09:34 |
| FourFire | ok, fair enough | 09:35 |
| @kanzure | i am open to the idea | 09:35 |
| @kanzure | of not having him around | 09:35 |
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| FourFire | maybe, have the creator further diversify it's dialogue? | 09:39 |
| chido | I like him | 09:46 |
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| drewbug | I like him, too. | 10:04 |
| drewbug | Or her. | 10:04 |
| drewbug | Or it. | 10:04 |
| chido | them. | 10:04 |
| drewbug | Yeah, but sometimes people get mad at me for using "them" as a singular pronoun. | 10:05 |
| gradstudentbot | Wasn't there a paper about that? | 10:06 |
| chido | sometimes people get mad at me when I don't | 10:06 |
| chido | gradstudentbot: stop reading gender studies | 10:08 |
| gradstudentbot | Wow, I'm definitely not including this data in the paper. | 10:08 |
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| FourFire | drewbug I use them sometimes | 10:21 |
| FourFire | but a bot is clearly it | 10:21 |
| drewbug | Why? | 10:21 |
| FourFire | my mind-feel says so | 10:21 |
| FourFire | no agency | 10:21 |
| FourFire | it's not a person | 10:21 |
| drewbug | Ships can be "her", though. | 10:21 |
| gradstudentbot | Yeah, it should take me about 2 days. | 10:22 |
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| justanotheruser | Hello gradstudentbot | 17:43 |
| gradstudentbot | Why did I go to grad school? | 17:43 |
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| Vutral | hi justanotheruser | 18:38 |
| Vutral | ... i need dmso | 18:38 |
| justanotheruser | Vutral: can you not order it online? | 18:39 |
| Vutral | hm i could | 18:39 |
| Vutral | i guess | 18:40 |
| Vutral | i need to check if they ship it | 18:40 |
| Vutral | there are some laws on shipping chemicals | 18:40 |
| Vutral | which are more or less useless partially | 18:40 |
| Vutral | liek that you cant ship F | 18:40 |
| justanotheruser | Vutral: synthesize it from stuff you can order | 18:44 |
| Vutral | did that before | 18:46 |
| Vutral | but then i need to waste solvents | 18:46 |
| Vutral | ^^ | 18:46 |
| Vutral | or consult the chemical seller of my trust | 18:47 |
| Vutral | i think i found some kind of ""movement"" which says dmso is good for skin | 18:49 |
| Vutral | and they sell 99,999% dmso because of it | 18:49 |
| Vutral | lol | 18:49 |
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| justanotheruser | Favorite podcast? | 19:51 |
| justanotheruser | Vutral: the wiki says it is being researched to help cancer patients | 19:52 |
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| Vutral | yeah still its toxic if pure | 20:28 |
| Vutral | but i dont like paying for transporting water | 20:28 |
| Vutral | +g+ | 20:28 |
| Vutral | i just wondered if capsicum plants got intresting alkaloids beside capsaicine | 20:29 |
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| Vutral | i think if i dont find an analysis i will go over to look for its genome ^^ | 20:30 |
| Vutral | thats easier to find *g* | 20:30 |
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| Vutral | The capsicum transcriptome DB: a "hot" tool for genomic research. | 20:31 |
| Vutral | dx.doi.org/10.6026/97320630008043 | 20:32 |
| Vutral | all this stress of seeking some breakfast | 20:33 |
| Vutral | i could really need a robot which can make eggs | 20:34 |
| justanotheruser | Vutral: how much of an inconvenience would you say having chemicals shipped, or having to synthesize them yourself is? (a bit of market research) | 20:39 |
| Vutral | well having them shipped can be stress if the seller doesnt keep records of stuff properly | 20:42 |
| justanotheruser | Vutral: Are you a hobby chemist? | 20:43 |
| Vutral | that doesnt matter for that | 20:43 |
| Vutral | if he doesnt keep records you have to confirm that you received the chemicals at least | 20:43 |
| Vutral | i can go to the university to the chemical trade they have there | 20:44 |
| justanotheruser | Vutral: Yeah, I realize. I was just curious if you were professional. | 20:44 |
| Vutral | well i did bioinformatics a while ^^ | 20:45 |
| Vutral | i mean i guess everyone can make dmso ^^ | 20:46 |
| Vutral | in a quick dirty and dangerous way | 20:46 |
| Vutral | but hm ^^ | 20:46 |
| Vutral | i dont like feeling like a microbe | 20:46 |
| justanotheruser | Vutral: Microbes make dmso? | 20:47 |
| Vutral | no | 20:48 |
| Vutral | but if you engineer an organism ^^ | 20:48 |
| Vutral | and you dont want some kind of marking that its a GMO | 20:48 |
| Vutral | you use dimethylsulfate | 20:48 |
| Vutral | ^^ | 20:48 |
| Vutral | and you can make dmso from dimethylsulfide ^^ | 20:48 |
| justanotheruser | what is ^^ | 20:48 |
| justanotheruser | a bird? | 20:48 |
| Vutral | a bat | 20:48 |
| Vutral | i guess | 20:48 |
| Vutral | or 2 eyebrows | 20:48 |
| justanotheruser | oh | 20:48 |
| Vutral | no idea why i type it so frequent | 20:49 |
| Vutral | but some people find it more friendly | 20:49 |
| justanotheruser | ¯\_(ツ)_/¯ | 20:49 |
| Vutral | have you tried shooting genes in mcirobes with dimethylsulfate ? | 20:49 |
| Vutral | i wouldnt do it with strict personal safety ^^ | 20:50 |
| Vutral | without | 20:50 |
| Vutral | ^^ | 20:50 |
| Vutral | 10 gramm or so suffice to alkylate all dna in a human | 20:50 |
| gradstudentbot | No, you definitely have a right to your own opinion. I just.. wish you wouldn't voice it. | 20:50 |
| justanotheruser | Vutral: no, but I plan on picking up amateur chemistry | 20:50 |
| Vutral | i made a channel for interdisciplinary science | 20:50 |
| Vutral | thought there arent many people in it yet ^^ | 20:50 |
| Vutral | i hope sometime there will be *g* | 20:50 |
| justanotheruser | what is it? | 20:51 |
| Vutral | ##interdisciplinary | 20:51 |
| @kanzure | https://github.com/mitsuhiko/flask-sqlalchemy/issues/60 | 20:54 |
| @kanzure | "Here's the scenario: you have some pre-existing sqlalchemy models that you are using to manage your ultra-awesome patch clamp microdialysis beowulf cluster. One day, you decide that you want a simple python web app to expose dish health/status to your meddling advisor, while he's away in Sweden at some technical conference living it up. What is a programmer to do? Maybe something like this." | 20:54 |
| @kanzure | oh, wait that was me | 20:54 |
| @kanzure | fuck | 20:54 |
| gradstudentbot | Hood life: https://www.facebook.com/photo.php?fbid=296519020495014 | 20:54 |
| n_bentha | i feel like i'm lost | 20:55 |
| n_bentha | what is the topic? | 20:55 |
| justanotheruser | n_bentha: are you confused? "biohacking, nootropics, transhumanism, open hardware" | 21:02 |
| Vutral | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC204052/pdf/aem00126-0050.pdf baceteria make dmso | 21:02 |
| n_bentha | why are we discussing dmso? | 21:02 |
| Vutral | it was on topic some minutes ago | 21:03 |
| Vutral | ^^ | 21:03 |
| justanotheruser | n_bentha: I would consider it biohacking | 21:03 |
| Vutral | yeah dmso is a common solvent | 21:03 |
| justanotheruser | also, science and chemistry seem to be on topic in this channel even though it isn't explicitly stated | 21:03 |
| justanotheruser | Vutral: are you going to replicate their experiment? | 21:04 |
| Vutral | i worked with fungii | 21:04 |
| Vutral | candida | 21:04 |
| Vutral | a bit | 21:04 |
| Vutral | ^^ | 21:04 |
| Vutral | but i need to build a new bioreactor/incubator | 21:04 |
| Vutral | for experiments | 21:04 |
| justanotheruser | Vutral: What is your professional field? Biology? | 21:05 |
| Vutral | more chemistry | 21:06 |
| gradstudentbot | Are you published? | 21:06 |
| justanotheruser | okay cool | 21:07 |
| n_bentha | oh ok...just thought dmso was so common that it was a waste to biohack it into a organism | 21:07 |
| justanotheruser | Well I'm going to go. Nice talking to you. Is anyone going to the Texas Bitcoin conference? | 21:08 |
| justanotheruser | Will check answers when I come back | 21:08 |
| Vutral | well i got knowledge on genetics medicine chemistry and biology | 21:08 |
| Vutral | also informatics and engineering | 21:09 |
| Vutral | so this room is right for me | 21:09 |
| Vutral | good luck justanotheruser | 21:09 |
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| @ParahSailin | dmso is biogenic though | 21:21 |
| @ParahSailin | plankton emit it, thats why we associate dmso with sea smell | 21:21 |
| n_bentha | Vutral, use a protein scaffold for your enzymes. | 21:24 |
| n_bentha | Will help the efficiency/productivity of the bacteria | 21:24 |
| n_bentha | http://www.ncbi.nlm.nih.gov/pubmed/23357532 | 21:25 |
| paperbot | http://libgen.org/scimag/get.php?doi=10.1016%2Fj.copbio.2013.01.003 | 21:25 |
| Vutral | intresting | 21:30 |
| Vutral | so i am eating cake drinking green tea and some chai tea be back in a bit | 21:47 |
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| --- Log closed Sun Jan 26 00:00:45 2014 | ||
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