2014-06-14.log

--- Log opened Sat Jun 14 00:00:34 2014
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kanzurebeep05:36
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FourFireboop06:11
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kanzurethat's boring10:06
delinquentme^10:07
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kanzurewhat?10:08
chris_99http://hackaday.io/project/1376-PyPPM%3A-A-Proton-Precession-Magnetometer-for-all!10:08
chris_99seems interesting10:08
kanzure.title http://pastebin.com/2qbRKh3R11:01
yoleauxALL CREDIT CARD PIN CODES IN THE WORLD LEAKED11:01
chris_99hahaha11:02
chris_99i'm guessing 0000 - 999911:02
chris_99scary shit right there!11:02
kanzureyep11:03
joepie91_it's amazing how I can track the spreading of that link11:04
joepie91_from one channel, to #swhack, to here11:04
joepie91_lol11:04
kanzureall things go through irc11:05
dingolol11:09
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kanzureantibody stain visualization site thing http://www.visabl.com/11:39
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chris_99time to try out brlcad, fingers crossed it imports something a bit better than freecad12:00
kanzureconsider using python-brlcad (there's a bunch of stuff missing, but you can still access the underlying brlcad functions)12:00
kanzureyashgaroth: can an antibody stain be made for most proteins?12:01
chris_99what's the difference between that an brlcad?12:01
yashgarothpretty much12:02
kanzureyou get to use python instead of tcl12:02
chris_99ah ok12:02
kanzureyashgaroth: what things am i missing? http://diyhpl.us/wiki/dna/projects/12:02
gnushahttps://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=8b92a063 Bryan Bishop: also mention recombinant monoclonal antibodies >> http://diyhpl.us/diyhpluswiki/dna/projects/12:03
yashgarothbiopharmaceuticals in general, though most of them are monoclonals12:04
kanzuresomeone asked me the other day why custom dna is important12:05
kanzureranting about random crops with herbicide resistance is sort of a non-answer12:06
yashgarothI mean it's used every day in research labs, but if you're going for a list of stuff that's been commercialized then it's not bad12:06
yashgarothrant about cancer, people love that12:07
kanzurewell, with an actual ability to make custom dna, we could be doing other things12:07
yashgarothDNA vaccines, if those ever get off the ground12:07
yashgarothoh and gene therapy stuff in general12:08
yashgarothwait, by "we" do you mean us with a dna synthesizer?12:10
kanzuresort of, not specifically us, but including us12:10
kanzurewith larger plasmids we could proably get entire metabolic pathways from one organism to another12:10
kanzure(even if it requires lots of tweaking)12:10
kanzure*probably12:10
yashgarothtransferring genes between species often requires synthetic DNA to compensate for differences in codon preference12:12
yashgarothbut of course that's like 5% of the work involved in making tomatoes generate fish antifreeze protein or whatever12:14
yashgarothI'm not experienced with trying to convince people who have no knowledge of molecular biology on the merits of it, really12:16
kanzurea lot of it seems to be "finding really obscure industrial use cases"12:16
kanzure"hey there's like 2 oil refineries that could use this enzyme to get a 20000% efficiency boost" "uh...."12:17
kanzureon the other end of the spectrum are the sensor/diagnostic people12:18
yashgaroththe bulk of12:19
yashgarothwhoops hang on12:19
yashgarothbulk of DNA synthesis work, like in terms of total base pairs, is genome synthesis or high-throughput screening for drug discovery12:20
kanzurei suppose genome synthesis' big use case is situations where you don't already have that organism laying around12:20
yashgarothor when you'd need to delete a bunch of it12:21
yashgarothdelete/modify12:21
yashgarothand screening stuff, while using the same basic principles as gene synthesis, is just 'generate a billion random sequences and do phage display'12:22
kanzureright12:22
yashgarothif you have an enzyme from organizm X that would improve organism Y, you identify modifications to make, maybe with a few variants, and have them made12:23
yashgaroththen it's making a thousand clones with that gene added, and months to screen for one that it works well in12:24
yashgarothclones as in modified cells or organisms12:24
yashgarothnonetheless I would still like a DNA synthesizer if you clear it with DHS12:28
kanzuredo you think the current ones are under the jurisdiction of the DHS?12:31
yashgarothit's a very grey area12:31
yashgarothnot directly like 'oh we gotta wait for our DHS synthesizer license renewal to come in'12:32
yashgarothI'm trying to think of a good comparison...something vaguely like precursor chemicals maybe12:34
yashgarothmixed with, like, building your own ICBM-compatible GPS circuit12:38
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kanzurehttp://2008.igem.org/Team:Imperial_College "First by utilising an endogenous light-sensing mechanism, the bacteria is captured in the desired location using 3D holography. Next bacterial locomotion is suspended in the region of interest using a recently-discovered clutch mechanism. This involves disengaging the flagellum from the motor protein. Finally, when our bacteria are stationary in the correct location, the biomaterial production is ...13:11
kanzure... triggered. These biomaterials can self-assemble to form a 3D bio-scaffold."13:11
kanzure.title https://www.youtube.com/watch?&v=pqEmKkY5DxA13:11
yoleauxBiofabricator13:11
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kanzureseba--: btw, your local school keeps winning all the igem competitions. you might want to go stalk them.13:41
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kanzurehttp://www.ardeypharm.de/en/ "Nissle 1917 is a commercially available non-pathogenic, probiotic strain of E. coli. It has been successfully used to treat gastrointestinal disorders including colitis and intestinal bowel disease and shows little immunostimulatory activity."13:49
kanzurehttp://2008.igem.org/Team:MIT "Streptococcus mutans, the main cause of dental caries, binds to glycoproteins on the teeth. A clinical study (Kelly CG et al.; Nature Biotechnol. 1999) isolated the 20aa functional segment (p1025) that S.mutans uses to attach to the teeth. p1025 competitively inhibits the binding of S.mutans, causing unharmful bacteria to grow in its place, preventing the recolonization of S.mutans for 90 days. We are ...13:54
kanzure... engineering Lactobacillus bulgaricus, a bacteria commonly found in yogurt, to produce and secrete this peptide under a promoter activated by lactose."13:54
kanzurewtf? http://2009.igem.org/Team:Todai-Tokyo "A large part of the world is bitter towards the act of smoking. However, many people like smoking or cannot quit. You might be one of such person. As a solution, what if a noxious smell is emitted from your mouth if you smoke by braking the "non-smoking promise"?? Your breath will stink and all the people around you: professors, friends, family members, and even your boy/girl friend will leave you. ...14:05
kanzure... You will have not choice but to live in isolation...."14:05
chris_99haha, what's' their proposition?14:05
kanzuremicrobe14:07
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seba--kanzure, i know14:28
kanzurealright14:28
seba--kanzure, i'm at it14:28
kanzurehttp://2009.igem.org/Team:UCL_London (fluorescent proteins to indicate different types of stress)14:32
seba--kanzure, well my gf will go into a GMO PhD biotech now, so ... lol14:39
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gnushahttps://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=7210c215 Bryan Bishop: various igem projects >> http://diyhpl.us/diyhpluswiki/dna/projects/15:14
AshleyWafflehey so brain computer interfaces can mostly just do input right now, right?15:18
AshleyWafflelike recieve data15:18
AshleyWafflelets say they could output15:18
AshleyWaffleA) do we know which part of the brain holds learning, so that you could feed info for example B) what is the theoretical maximum rate15:18
chris_99have a look a transcranial magnetic stimulation etc.15:18
chris_99*at15:18
AshleyWafflehm15:19
AshleyWaffledoes it have the level of precision needed for "downloading info" to the brain15:19
AshleyWaffleie books or osmething15:19
chris_99no15:19
kanzureyes, but your brain wouldn't understand it15:20
AshleyWaffleAh15:20
AshleyWaffleIs there a way to do it in such a way that it would?15:20
kanzureHas anyone ever done like which that?15:20
AshleyWafflePerhaps you just need to reverse engineer how the information is encoded that is recieved neurally15:20
AshleyWaffleWhat?15:20
yashgarothmaximum theoretical rate is ~1 martial art style/sec, per the matrix15:20
AshleyWafflelol15:21
AshleyWaffleand yeah I mean matrix learning15:21
AshleyWaffleim interested in it15:21
AshleyWaffleI struggle with motivation and other issues, I could just consume all books related to psychology, NLP, and self-help in like 5 minutes or something15:21
AshleyWaffleor at least without needing to be motivated to read them lol15:21
kanzurethere are drugs that can change motivation15:21
-!- seba-- is now known as seba-15:22
kanzurealso deep brain stimulation and other forms of brain damage15:22
AshleyWaffleyes but even then my goal would still be accelerated learning15:22
AshleyWafflebecause self-improving15:22
AshleyWaffleis there a theoretical limit on how much someone can know?15:22
AshleyWaffleor does the brain have tons of "extra space"15:22
kanzureyes, look up thermodynamic limits of superobjects15:22
seba-what15:23
AshleyWafflewell... the only limits arent just thermodynamic in nature right? lol15:23
kanzurethere is an information theoretic limit to the amount of information storable per unit of energy/atom15:23
AshleyWaffleI mean a non-augmented brain15:23
kanzureit is a maximum limit15:23
kanzurewell, you asked..15:23
AshleyWaffleno, I mean information per human brain15:23
seba-lol15:23
AshleyWafflehi seba-15:23
seba-hi AshleyWaffle15:23
kanzuremerkle did an estimation of the information content of the human brain15:23
AshleyWafflecontent or capacity?15:24
kanzurewhatever15:24
AshleyWafflemmm15:24
AshleyWafflewhat is it?15:24
kanzurehttp://www.merkle.com/humanMemory.html15:24
FourFireAshleyWaffle, hello!15:24
seba-AshleyWaffle, bunga bunga?15:24
AshleyWafflecan we get a measurement in books?15:24
AshleyWafflehey FourFire15:24
seba-in LoC?15:25
AshleyWaffle?15:25
FourFireafaik BCI are input only currently, but you can look into TransCranial Stimulation and LED shining through the skull15:25
kanzureugh, you are all terrible people15:25
seba-kanzure, why15:25
kanzurehow the fuck does electrophysiology work if you can't read neural signals15:25
kanzureyour understanding of the world is totally inconsistent15:25
seba-oh that.15:26
AshleyWaffle???15:26
FourFireAshleyWaffle, I would hazard that with current technology it would be more effective to do some of the more scientifically proven hynosis methods with VR (sight and sound) which is optimized for learning15:26
kanzurehttp://en.wikipedia.org/wiki/Electrophysiology#Extracellular_recording15:26
seba-:o15:26
FourFirewe can't beam knowledge in curcumventing the senses yet15:26
FourFirethere are some experiments being done in erasing memories in mice, but that's the opposite of what you're asking about15:27
seba-just implant a SD card and a brain2ttl converter15:27
kanzurehttp://en.wikipedia.org/wiki/Microelectrode_array15:27
AshleyWaffleFourFire: I see, interesting15:28
FourFirekanzure, please, don't be so misanthropic, I might not be as great and knowing as you, but I may yet help the cause...15:28
AshleyWaffleFourFire: which techniques are proven15:28
seba-we should implant into frigid girls an orgasm on demand module15:28
kanzureFourFire: just don't say wrong things15:28
FourFireAshleyWaffle, the limits aren't brain capacity, they are bandwidth15:28
kanzurewhat15:28
FourFire(for the time being, that is)15:28
AshleyWafflekanzure: sometimes people are wrong :/15:28
AshleyWaffleFourFire: also the word you're looking for isn't misanthropic15:29
seba-i am15:29
AshleyWaffleFourFire: Oh? What's the quickest way to learn15:29
FourFirekanzure, I can't not say wrong things without knowing the universal truths, but what I can say are approximations based on my best knowledge, which may or may not be superior to the person i am conversing with15:29
kanzurethe quickest way to learn is to limit yourself to things that have extremely steep learning curves15:29
kanzureFourFire: i have no clue how your "best knowledge" would tell you that electrophysiological recordings are fake....15:30
kanzureseba-: i'd vote in support of orgasmobuttons, pudendal nerve stuff, etc.15:30
kanzureseba-: unfortunately, it would work in both females and males, not meeting your frigid girls-only requirement..15:30
FourFireAshleyWaffle, well schools suck, and I am not proven to be skilled at it, but I've found I can learn something which interests me where I absolutely must gather more knowledge in order to think about it in my head15:31
FourFireso, yeah steep learning curve, + interest in modeling with the subject in question15:31
AshleyWaffleadjusting for learning curves15:31
seba-kanzure :-(15:31
kanzureseba-: is that really the end of the world haha15:31
AshleyWaffleso the curve for everything = X15:31
AshleyWafflewhat is the quickest way to learn15:31
seba-kanzure, imagine porn with orgasmic feedback15:32
FourFirekanzure, I didn't say anything whatsoever about electrophysiological recordings15:32
kanzureFourFire: you said that brain computer interfaces can't read15:32
kanzureFourFire: that they can only stimulate15:32
kanzureseba-: i dunno if i can, what would that mean15:32
AshleyWaffleplease dont fight ;-;15:32
FourFirewait what?15:32
FourFireI meant the reverse, of course, lol15:33
AshleyWaffleFourFire: dont engage :(15:33
kanzureFourFire: 15:25 < FourFire> BCI are input only15:33
AshleyWafflekanzure: yeah input from the computers perspective15:33
AshleyWafflenow pls no fight15:33
seba-kanzure, it's like with sound, or visual, only that you would achieve orgasm at the same time and way as in the porn video15:33
kanzureAshleyWaffle: nobody is fighting, relax15:33
seba-we could call it 5D porn15:33
FourFirethey can't stimulate, can only read (unless you mean intrusive, which I don't)15:33
FourFireinput... from the user... user input15:33
kanzureseba-: oh i see, i dunno what the time-to-orgasm is after stimulation of that nerve, might not be a direct relationship15:34
FourFireAshleyWaffle, don't worry about us arguing, I understand that a little conversational rustle tustle is a requirement for conversing with kanzure ;)15:34
seba-kanzure, what about anal electroshocks, i've heard you ejaculate15:34
seba-+that15:34
kanzurewhy do you guys insist that you have to fight me to talk with me15:35
seba-i wonder if that's true, if also girls achieve orgasm, by anal electroshocks15:35
seba-AshleyWaffle, could you try?15:35
kanzurestop calling it fighting15:35
FourFireof course, if you're going to be putting electrodes in places withy nerves you can force inputs15:35
AshleyWafflelol15:35
kanzureseba-: pudendal nerves work just fine iirc15:35
AshleyWafflekanzure: oh youre a wimminz? :D15:35
kanzure.g wimminz15:35
yoleauxhttp://www.urbandictionary.com/define.php?term=wimminz15:35
kanzure.ud wimminz15:35
seba-kanzure, how do you stimulate it?15:36
kanzure.u wimminz15:36
yoleauxNo characters found15:36
AshleyWaffleLOL15:36
seba-could you use electricity15:36
seba-hm15:36
FourFirebut I doubt you can pass on *knowledge* except on the order of single bytes that way with current tech15:36
kanzureseba-: ultrasound15:36
kanzureseba-: ultrasound, electricity, etc15:36
seba-oh15:36
AshleyWafflethe urban dictionary page is awful15:36
seba-how do you do it with ultrasound?15:36
kanzureFourFire: knowledge might not exist in any biologically relevant way15:36
kanzureseba-: http://diyhpl.us/~bryan/papers2/neuro/ultrasound/15:36
FourFire"w'ere gonna send an SOS, when you're jizzing, that's a dash, when you're dryclenching, that's a dot"15:36
seba-oh15:36
seba-have you tried it?15:37
kanzurenope15:37
kanzurebut there's bunches of research15:37
nmz787why do android file paths have so many directories in them?15:37
FourFirekanzure, your definitions are vague and an attractor to pointless argument.15:37
FourFirekanzure, people can write books15:37
nmz787like in compiling projects15:37
kanzureFourFire: which definition is vague pls15:37
FourFirebooks contain knowledge15:37
kanzurehaha no15:38
FourFiretherefore people can contain AND pass on knowledge15:38
kanzurebooks do not contain knowledge15:38
seba-it would be interesting15:38
seba-this is the future15:38
seba-masturbation devices using this15:38
kanzureknowledge is what happens when you read a book and think about the symbols, and then try to reconstruct the meaning the author intended15:38
gradstudentbotWow, very ethical.15:38
FourFirearight, books contain patterns which can be decoded using human brains into knowledge, which is stored biologically15:38
chris_99gradstudentbot, get back to research boy!15:38
gradstudentbotDoes this look contaminated to you?15:38
seba-you could make female panties having this inside15:38
kanzureit may not be stored biologically at all15:38
AshleyWafflegradstudentbot: whats unethical?15:38
gradstudentbotWhere did you put my samples?15:38
seba-so when they are bored they can just engage it15:39
kanzurethe human brain is quite lossy at remembering certain things15:39
nmz787its all memes15:39
AshleyWaffleare there male panties?15:39
kanzureAshleyWaffle: he means the orgasm button may be unethical15:39
AshleyWafflekanzure: thats a pretty disgusting position to hold15:39
seba-AshleyWaffle, probably15:39
FourFireAshleyWaffle, you're talking about wireheading15:39
FourFirewhich has ethical qualms attached15:39
seba-anyway15:39
kanzureAshleyWaffle: radstudentbot? yeah, well..15:39
AshleyWaffleFourFire: huh?15:40
seba-maybe this nerve gets stimulated15:40
nmz787yo dawg i heard you like knowledge, so i encoded your meme into book, so you can deocde while you reload15:40
seba-by anal probes15:40
AshleyWaffleuh fuck ethics?15:40
gradstudentbotMan, if only I could biopsy his organs.15:41
FourFire"why do you guys insist that you have to fight me to talk with me" I don't AshleyWaffle is, I just find it difficult to communicate relatively simple concepts to you, which is annoying since you seem intelligent, just slightly malicious in your (probably not actually deliberate) misunderstanding15:42
kanzuremaybe your concepts aren't as simple as you've been mislead into thinking15:42
kanzure(human) "memory" is extremely weird15:42
kanzureand "knowledge"15:42
seba-AshleyWaffle is probably working for you15:43
FourFirekanzure, ok, how is "knowledge" as you define it, stored or transferred in some way involving brains, which is not biological in nature?15:43
seba-how much did you pay her?15:43
kanzureworking for which one?15:43
kanzureFourFire: i'm not sure if i would say it is; i would say that human brains are able to communicate with each other, and then they reconstruct messages and on each end15:43
seba-i wonder if anyone has done research on this hm15:43
seba-http://www.mmsinternational.com/int/681/gastroenterology-pudendal-nerve-stimulation15:44
seba-lol15:44
FourFirekanzure, then it's like i said with a pattern being encoded and put into books, which is then decoded inside a brain15:44
FourFireand thus *knowledge* has been passed15:45
kanzureyeah, but you wouldn't say the knowledge is in the book15:45
kanzurelike you did15:45
FourFireyes, perhaps it's too abstract a concept for you to take seriously15:45
kanzurei would say that if knowledge is "communicated" at all, it is by each side of the communication generating it on its own or something, based on their attempts at communication15:45
seba-oh15:46
seba-there's a word for this15:46
seba-electroejaculation15:46
seba-lol15:46
kanzureseba-: hmm i thought i had a paper or two about this, but i can't find it15:46
seba-http://en.wikipedia.org/wiki/Electroejaculation15:46
FourFirethis damned bandwidth limitation is encouraging me to compress my information transfer into abstractions15:46
seba-i wonder if this works on humans15:46
kanzureof course it does15:46
seba-does it work also on women?15:46
kanzureyes15:46
seba-nice15:46
seba-i must try it15:46
kanzurevarious car injuries have caused damage to this nerve in the past15:47
FourFireso instead of saying "I.I.S.A.A.P.I.A.B.A.T.D.I.A.B" I say "knowledge is in books"15:47
kanzurenow you have a reason to drive even more recklessly15:47
seba-Electroejaculation is usually carried out under a general anesthetic.15:47
seba-huh15:47
FourFirewhy can i say this to any other person, but not you?15:47
seba-why?15:47
seba-is it painful?15:47
kanzureseba-: depends on their method of stimulation! i imagine that "electrojaculation" might just be "electroshock" without specifically targetting a certain nerve.15:47
kanzureFourFire: because i am not okay bullshitting you15:48
kanzureFourFire: unless i am trolling you on purpose15:48
kanzurein which case, sky's the limit15:48
gradstudentbotIs that published?15:49
seba-http://en.wikipedia.org/wiki/Erotic_electrostimulation15:49
seba-lol15:49
seba-wtf15:49
seba-http://upload.wikimedia.org/wikipedia/commons/thumb/b/b7/Electric_Stimulation.jpg/800px-Electric_Stimulation.jpg15:49
FourFirefine, so the brains don't ever contain knowledge...15:49
seba-lol15:49
jrayhawk_transhumanism.jpg15:50
FourFirethey just contain the biological-alphabet equivalent to a decoder that can parse PI into any arbitrary information15:50
FourFireand books contain alphabet PI15:50
kanzurehaha yeah right,15:50
gradstudentbotI punched my PI and that's why I work here now :\15:50
kanzureyou can show people the same book and not everyone will extract the same information15:50
nmz787PI? Private Investigator?15:51
FourFirebooks contain alphabet PI, kanzure, and humans can write alphabet PI into books, therefore the information which can be decoded from alphabet PI is being transferred somehow!15:51
kanzureprincipal investogator :p15:51
kanzureFourFire: how did this turn into information? i thought you said knowledge15:51
nmz787re the non gradstudentbot comments?15:51
gradstudentbotI have to read all these articles.15:51
nmz787alphabet principal investigator?15:51
kanzurehrm15:52
kanzuregood point15:52
nmz787a prof that studies language?15:52
FourFireso when you say " knowledge might not exist in any biologically relevant way" how does it even have meaning?15:52
FourFirethis is what I mean by your definitions being vague and an attractor to pointless argument15:52
kanzureit means "folk psychology often encroaches far beyond the theoretical studies' results"15:53
kanzure"folk psychology is not necessarily going to lead to results where your understanding of how the brain operates happens to map to reality"15:53
seba-Something went haywire with his balls, and before a procedure to fix the damage a brisk military nurse hooked him up to a device without explaining what she was doing. It wasn't a rectal deal like this thing, more like adhesive pads hooked to a box.15:53
seba-Nurse Ratched grabbed his dong with a specimen cup in hand and hit the switch. He described the orgasm as mind blowing. With a grin from ear to ear he asked where he could purchase one of the devices.15:53
seba-hm15:53
FourFirekanzure, because your were purpoisely being obtuse in such a way that i can only suspect you wanted me to completely redefine whatever you're waving as "knowledge" into something I can actually use to talk to you about15:54
FourFireyou*15:54
kanzureFourFire: look, if you want "matrix-style learning", you will first have to investigate whether or not it is possible, not just make up whatever definitions you want15:54
kanzurereality owes you nothing15:54
kanzureit will not just happen to map directly to notions of memory that turn out to be physically implausible15:54
FourFireplease explain "knowledge might not exist in any biologically relevant way" in different words15:54
kanzure15:52 < kanzure> it means "folk psychology often encroaches far beyond the theoretical studies' results"15:55
FourFireok15:55
nmz787seba-: for cattle i read they use fake cows, which they get the bull to mount... i wonder if they use the method you mention too15:55
seba-nmz787 they do15:55
kanzurewhat? really?15:55
nmz787it might freak the bull out15:55
seba-but i'm wondering if it's used in males15:55
seba-human ones15:55
nmz787he would be an o'organic' bull anymore maybe :P15:55
nmz787they o in o' was a typo15:56
FourFireI agree that different people can get different "knowledge" out of the same book15:56
gradstudentbotMy code works. I have no idea why...15:56
nmz787FourFire: that's the whole idea of stenography15:56
nmz787the decoder matters15:57
nmz787same thing with an SD card and a computer15:57
FourFirethere is no way that information exists in brains in anywhere near something like it does in computers and other nonbiological information storage systems15:57
nmz787if the deocoder doesn;t work, blah, garbage15:57
nmz787same in DNA with frameshifts15:57
nmz787as they say in thailan, 'its same same'15:57
FourFirenmz787, in this case I mean something with no "hidden messages" but sure15:57
nmz787or chemical reaction ordering15:58
nmz787it matters15:58
nmz787or the end result differs15:58
seba-nmz787, https://www.youtube.com/watch?v=TmZ19Sxab_415:58
FourFiredid we scare AshleyWaffle off?15:58
kanzurenmz787: someone asked me about "useful projects that could be done if whole genome synthesis was a few million times cheaper", http://diyhpl.us/wiki/dna/projects/ am i missing anything obvious?15:58
nmz787kanzure: yea, more drugs... artemisinin, etc...16:01
seba-kanzure you also watch it16:01
seba-it's interesting16:01
kanzureseba-: http://www.psas.nl/artikelen/TENS.pdf16:01
kanzureseba-: there are others but i don't remember them at the moment16:02
seba-i wonder if it works on females16:02
kanzure.title https://www.youtube.com/watch?v=TmZ19Sxab_416:02
yoleauxbull electroejac16:02
FourFireAshleyWaffle, the thing is, that I was about to explain to you, that we know oursenses can pass on information into our brains, but we honestly have no idea what nerve signal encoding protocols exist and which to use in the case of directly stimulating nerves, so when I say "I doubt you could pass on *knowledge* past some bytes, I mean you might be able to induce pavlovian responses or something like that, but nothing more until we16:02
FourFirelearn more about how info goes around the body16:02
kanzurenmz787: well, drugs are kinda obvious i guess, but i'm looking for other things16:02
kanzurenmz787: i know i've seen all sorts of magical transgenic things in the past, but i wasn't keeping a list16:03
kanzurethis one was pretty clever- "treat allergic rhinitis by engineering Staphylococcus epidermidis, a microbe endogenous to the human nasal flora, to secrete a recombinant histamine-binding protein in response to the elevated histamine concentrations of an allergic response"16:03
FourFireAshleyWaffle, so, like I said, the most effective method of learning with current tech might be VR + hypontism + optimized lessons/video/gamelevel scenarios for teaching you whatever skill16:03
nmz787kanzure: i don't think anything is obvious to uneducated people16:03
FourFirenothing like in the matrix16:03
seba-kanzure but this stopped orgasm, i want the opposite16:03
kanzureFourFire: you know people actually study learning, and i'm pretty sure hypnotism is not the method that comes out on top16:04
kanzureseba-: yeah, it goes both ways depending on type of stimulation, iirc16:04
seba-oh16:04
kanzureseba-: the hackerspace in prague built a device to do it16:04
kanzurepasky: do you remember the name of the brmlab orgasmotron16:04
seba-really16:04
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seba-why do they use it for16:04
kanzurei think pasky might know16:04
FourFirekanzure, well I don't know if you'd classify causing people to be in a mental state which facilitates learning as hypnotism16:05
seba-watch the video, then google terrorist stuff, then watch more cow semen collection videos. repeat this for 8 hours then some guy at the nsa will have to watch the bull semen videos over and over while analyzing them for codes and secret messages.16:05
seba-ahahahhaha16:05
FourFireyou could do that with trained cues, or controlled environmental factors, not that I know what those are16:05
kanzureseba-: only funny if they don't like it16:05
FourFireseba-, lel16:05
FourFirebecause of people like you seba- there's some people with weird boners working at the NSA16:06
kanzureyeah, like people who like math16:06
kanzuresickos16:06
nmz787i doubt neural codings are standardized within the species16:07
kanzureoh i didn't mean a specific neural ensemble encoding16:07
seba-http://commons.wikimedia.org/wiki/File:Electroejaculation.jpg16:07
seba-lol16:07
seba-wikipedia has everything16:07
FourFirekanzure, I hope to use the last one on your list someay16:08
FourFiresomeday*16:08
kanzuremy sarcastic comment about math?16:09
FourFireno, sorry "DNA vaccines"16:09
kanzureit's obviously referring to the fact that the nsa has a weird balance between math for defense and math for offense16:09
FourFirei's been done already, but what if you could do that on a person by person basis16:09
FourFire1$ to map a genome and then output an active retrovirus containing a "perfect" variant of their genome with all the broken disease alleles replaced with nice working ones16:11
FourFirejab them , get them to stay indoors for a week...16:11
FourFirebut then you've got to be realistic about these things, this type of technology won't exist for many decades16:12
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kanzureyeah, retroviruses don't exist16:13
kanzureduh16:13
kanzurewtf is his problem?16:13
seba- Volts are slowly increased until a man ejaculates. The majority of men are able to ejaculate in under 20 volts.16:14
seba-lol16:14
seba-this is funny16:14
seba-under 20 volts16:14
seba-haha16:14
kanzureit's pretty common16:15
kanzurei mean, it's depicted in the media often16:15
kanzuresold in stores, etc16:15
seba-bizzare16:17
kanzureremind me to never take you to a livestock store16:19
seba-Out of curiosity I took one of the pads from just above my knee and placed it on the under side of the head of my penis. OMG!!! Within 5 minutes I reached an ejaculation that was unbelievable.16:20
seba-lol16:20
seba-but this is not ok 5 min, i thought it's instantaneous16:20
jrayhawk_no, man, you have to take it slow with your pelvic floor. take it to a movie, buy it flowers...16:21
jrayhawk_you don't want to scare it off!16:21
seba-this is bizzare16:23
seba-i wonder if it really works, i can't find a human video16:24
seba-lol16:24
jrayhawk_well, you have to pay for those16:24
seba-hm16:25
seba-i guess it should work16:26
seba-why not16:26
seba-i just never thought about it16:26
seba-until today16:26
seba-lol16:26
kanzureit is very clear that you never dated anyone with an electricity kink16:26
seba-of course i didn't lol16:27
seba-anyway, i still don't get how you can use pulses to stimulate and destimulate16:27
seba-how does that work?!16:27
kanzuremembrane potential stuff16:27
seba-yes but is it frequency (waveform) or just amplitude (voltage/current) ?16:29
seba-hm16:33
seba-apparently DC works better16:33
seba-one guy said he achieved with DC a 2 min orgasm16:33
seba-interesting16:33
seba-oh16:34
seba-he inserts the probe16:34
seba-directly in his prostate16:34
seba-lulz16:34
seba-wtf16:34
seba-these people are crazy16:34
seba-kanzure, so do you know a girl with such kinks?16:47
kanzurehmm16:54
kanzuremaybe16:54
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seba-http://www.google.com/patents/US394113617:00
kanzure.title17:00
yoleauxMethod for artificially inducing urination, defecation, or sexual excitation17:00
seba-but it doesn't state anything about ejaculation17:07
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jrayhawk_experimentation with electrostimulation is somewhat common in the BDSM scene, though a large portion of that is just for pain's sake17:29
seba-jrayhawk_, it seems very interesting17:30
seba-jrayhawk_, you should do some research17:30
seba-i'm interested in some things17:30
jrayhawk_the extreme body mod scene had a lot more dedication to electrojaculation17:31
seba-jrayhawk_, that patent talks only about erection17:31
seba-i'm wondering if you keep at 20 V if you ejaculate17:31
seba-can you try?17:31
kanzurei doubt that people in "the BDSM scene" care about patents17:31
seba-it's a bit different position17:32
seba-of electrodes17:32
seba-than the BDSM scene17:32
seba-i wonder what happens17:32
seba-apparently 30 V make you shit yourself17:32
jrayhawk_"17:32 < seba-> can you try?" my expertise comes exclusively from exposure to videos from http://en.wikipedia.org/wiki/Shock_sites17:33
jrayhawk_i do not actually have particular interest or opportunity to try anything17:34
seba-oh :(17:35
seba-jrayhawk_ i thought you have this at home17:35
kanzurebecause he said two things?17:36
seba-kanzure yes17:36
jrayhawk_nope, but the BME community can probably help you out.17:36
jrayhawk_http://wiki.bme.com/index.php?title=Electrical_Play17:37
jrayhawk_I think a lot of their content, including the "Extreme" section,\ is paywalled.17:38
kanzure"too extreme for the internet at large"17:39
* kanzure shakes his head17:39
kanzureyou know, there used to be a time when i couldn't go a day without being tricked into viewing yet another shock site17:39
kanzuretimes'a changing17:40
jrayhawk_I am sure the BME Pain Olympics figured heavily into those shock sites.17:40
kanzureit seems like cheating if all the content was from a single source17:40
jrayhawk_oh, and their forums, apparently17:44
jrayhawk_i guess that makes sense.17:44
seba-kanzure is your girlfriend on irc17:45
seba-so that she can try this17:45
seba-or ex gf17:45
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kanzurei don't think any of my girlfriends were ever into electroanything17:47
kanzure(or me for that matter)17:47
seba-oh17:47
nmz787they weren't into thinking? or their heart beating?17:48
kanzureyeah, fuck hearts17:48
kanzurewait what?17:48
paskykanzure: multistim17:48
kanzureahh multistim heh17:48
kanzurewhat did it do again?17:48
nmz787"kanzure, sorry, I'm not into electrical-potential gradients"17:48
kanzurenmz787: "i am not into carbon-based lifeforms either"17:49
nmz787"i'm not into gradients"17:49
paskyhmm it had pressure regulators, electrodes, and maybe some other... output devices17:49
paskythey couldn't sell enough of them for the pricetag (about 1500USD), they plan to do a cheaper version sometime in the future17:50
kanzure"couldn't sell enough of them" is sometimes used as a euphemism for "they were selling too quickly"17:50
kanzureand the literal meaning is "they couldn't sell any"17:51
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seba-pasky, so have you tried this http://www.google.com/patents/US394113617:53
seba-can you shit yourself?17:53
seba-it says you can achieve erection by 20 V and then 10 V17:53
seba-if you keep at 20 V, do you orgasm?17:54
seba-can you try?17:54
seba-also it doesn't say if you need a higher voltage for shitting or for urinating17:54
seba-can you please try?17:54
kanzurewhy do you think everyone has tried this stuff18:01
kanzurepasky is just someone i know that goes to a hackerspace sometimes18:01
kanzureand that hackerspace has a machine some other people built18:01
seba-so he has access to this18:01
gradstudentbotCan I get my own desk?18:01
kanzure"I worked on the firmware for the "Applied Biosystems ABI Prism 310 DNA Sequencer"." https://news.ycombinator.com/item?id=789342318:01
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nellim almost done reading the transhumanist reader18:04
kanzureouch18:04
kanzurehow bad is it18:04
nellIt's bearable18:04
kanzurereally?18:04
nellNatasha is a hottie18:04
kanzurethat makes it bearable?18:05
nelllol18:05
nellI got Natasha's email to try and spin something together with transhumanism & the maker movement.18:07
nellalso does anyone here program lisp18:07
kanzurethere's a few lispers18:11
kanzurewhat do you mean "spin".. do you mean "write an article for hplusmagazine"? :(18:11
nellWow.. Awesome, I never knew about it18:13
kanzurenever knew about lisp?18:13
nellhplusmagazine18:13
nellI usually follow kurzweilai and singularityhub18:13
kanzurei regret telling you about it18:13
kanzureoh man those two are pretty bad too18:13
kanzurewhy do you read these18:13
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nellI don't really read, it's candy for my brain in the morning18:14
kanzurei see18:14
kanzurewell, as long as you recognize it's just infotainment18:14
gradstudentbotYeah, it's definitely impractical and fairly non-elegant at the same time.18:14
nellinfotainment, I'm very glad this has entered my vocabulary18:15
nellI gotta get back to scheme18:15
nellciao18:15
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kanzurei think this person was last around 2012-09-2518:15
yashgarothah yes 21:18 < yashgaroth> shut the fuck up alusion18:18
kanzurelovely18:19
kanzurehttp://www.wired.com/wp-content/uploads/2014/05/PowerRangers.jpg18:19
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nmz787http://karenkilgariff.bandcamp.com/track/look-at-your-phone18:55
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eudoxiai was too late to catch the lisper19:22
eudoxiai'm losing my edge19:22
kanzureyou can still rewrite nanoengineer for gene_hacker19:44
caterneudoxia: what were you going to do with him if you caught him19:44
eudoxiacatern: do i look like a guy with a plan? you know what i am? i'm a dog chasing cars. i wouldn't know what to do with one if i caught it! the mob has plans. the cops have plans. people who use haskell have plans. you know, they're schemers. that's why scheme is called scheme. schemers trying to control their little worlds.19:50
kanzure"Needle complex of Salmonella typhimurium" http://2010.igem.org/wiki/images/8/8c/HokkaidoU_Japan_Fig1.jpg19:57
kanzurenow that is nanotechnology19:57
kanzure"Its length is about 80nm and the diameter of its needle channel is about 2nm."19:58
eudoxiait looks like one of those spinny merkle/freitas things that would never work irl19:58
kanzurehttp://2010.igem.org/Team:HokkaidoU_Japan/Projects19:59
kanzurehttp://2010.igem.org/File:HokkaidoU_Japan_Fig6.jpg20:02
kanzurehttp://en.wikipedia.org/wiki/Type_three_secretion_system20:03
kanzure"The ability of intracellular bacteria to migrate between host cells."20:05
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kanzuremicrofluidic flow generator by coating microcapillaries with bacteria http://2010.igem.org/Team:SDU-Denmark/project-i20:43
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kanzure3d printing material (light-induced cell lysis release of polyhydroxybutyrate plastic) http://2010.igem.org/Team:Caltech20:59
gnushahttps://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=aa1333e5 Bryan Bishop: igem projects from 2010 >> http://diyhpl.us/diyhpluswiki/dna/projects/21:11
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kanzurewhat http://2011.igem.org/Team:Kyoto "We created new E.coli which hunts and eats insects. As such we named it Carnivorous E.coli. Carnivorous E.coli emits light when it is hungry. This will attract insects to it. Then, it secretes a viscous substance to capture the insects. The captured insects are digested by the chitinase in the secretion. Long story short, our Carnivorous E.coli can hunt."21:54
kanzurehttp://2011.igem.org/Team:NYMU-Taipei "To achieve this goal, we use a species of magnetic bacterium, Magnetospirillum magneticum AMB-1. We have chosen mms13, a transmembrane protein as our target for protein design in this bacterium, as it serves as a linker between reception of wireless magnetic field and optogenetic neuro-stimulation output. Regarding the neuroimmune response, we have utilized three genes to achieve neurosymbiosis within ...22:09
kanzure... glial cells: MinC, a division inhibitor, INV, a gene for invasion and LLO, a gene for facilitating escapes from phagosomes."22:09
kanzure"A pilus is typically 6 to 7 nm in diameter. During conjugation, a pilus emerging from donor bacterium ensnares the recipient bacterium, draws it in close, and eventually triggers the formation of a mating bridge, which establishes direct contact and the formation of a controlled pore that allows transfer of DNA from the donor to the recipient. Typically, the DNA transferred consists of the genes required to make and transfer pili (often ...22:17
kanzure... encoded on a plasmid), and so is a kind of selfish DNA; however, other pieces of DNA are often co-transferred and this can result in dissemination of genetic traits, such as antibiotic resistance, among a bacterial population. Not all bacteria can make conjugative pili, but conjugation can occur between bacteria of different species."22:17
kanzurehuh, i didn't know they had a 7 nm diameter22:17
gradstudentbotYou know, I hear you make more money being a garbage man.22:19
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kanzurereflectin thin films http://2011.igem.org/Team:Cambridge#/Project/Microscopy "This animation is composed of layers taken as the microscope was focused through the layers of a sample of reflective squid cells from the eye cup mounted in Phosphate buffered saline"22:35
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kanzuremore on that syringe protein http://2011.igem.org/Team:HokkaidoU_Japan23:31
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gnushahttps://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=062e285e Bryan Bishop: igem projects from 2011 >> http://diyhpl.us/diyhpluswiki/dna/projects/23:52
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