2014-09-16.log

--- Log opened Tue Sep 16 00:00:07 2014
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dbolserwho knows of 'manifestos' for open science?03:21
dbolseri.e. blogs about doing 'blah' and examples of people doing blah to effect x?03:21
dbolser(a bit vague I know, but someone wants to develop a database of 'principles' in open science with content and examples03:22
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heathdbolser: i've heard of something like this before06:42
heaththere is literally a thing called the open science manifesto: http://open-science.pen.io/06:43
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kanzuredbolser: panton principles08:14
kanzurepanton08:15
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dbolserheath, kanzure: many thanks08:33
dbolserhttps://titanpad.com/Bjxqo6ikD408:33
archels_"[...] the Neurophotonics Lab is developing a simple experimental system in which a small network of cultured neurons continuously exchanges information with a virtual environment implemented on a real-time computer; analogous to how a real organism interacts with its environment. It is postulated that the resulting system, a Simple Living Artificial Brain (SLAB), contains the minimal, but essential, components required by a cognitive organism, while b08:55
dbolserhow old is that?08:55
kanzurewhat? why would a 10 neuron neural network be any better in biology than a simulated 10 neuron neural network..08:56
kanzurewhat network size in their culture08:56
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archels_dbolser: someone is giving a talk on it tomorrow08:59
archels_kanzure: because simulated neurons are so immensely simplified it's laughable08:59
kanzurehow many neurons09:01
nmz787_iyeah I could see how farming the processing out to real neurons might enhance the overall system09:01
nmz787_ior do nothing09:01
nmz787_ibut that's why they 'postulate' that09:01
archels_I don't know. come to the talk :)09:01
archels_I've known that Kevin Warwick has been trying something similar for years09:02
nmz787_iwhere?09:02
archels_and I didn't like it back then either when I first heard about it09:02
kanzureted berg is the traditional name to throw around for "hooking up piles of neurons to flight simulators"09:02
kanzurekevin warwick not so much09:03
archels_Speaker: Noah Russel (Nottingham University)09:03
archels_I guess it would be cool if they could get to work on reprogramming neurons09:04
archels_any desired morphology and electrophysiology on demand09:04
kanzurehenry markram's lab was doing some of that by individually poking neurons i think09:05
kanzurewith patch clamp to force the network to reconnect09:05
kanzurei mean the would-be network09:05
kanzureuh... wait. that might be a lie.09:06
kanzurei don't recall which paper this was :(09:07
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dingodefinitely been on irc too long when you see people you know on bash.org09:24
chris_99haha09:25
eudoxiathe other day when it appeared on HN i searched and found kanzure has been immortalized in bash.org09:28
eudoxiahttp://www.bash.org/?10692809:28
chris_99haha09:29
kanzurethat was actually my dad stealing my screenname09:29
kanzurebecause apparently chatting with a relative over aim was a novel concept09:30
kanzuredunno who submitted it09:30
chris_99maybe your dad is an avid bash.org contributor09:31
kanzurehe dead09:31
kanzurealso no, wasn't quite the type to be aware of bash.org in his time09:32
chris_99oh sorry :(09:32
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kanzure.title http://people.xiph.org/~xiphmont/demo/neil-young.html10:21
yoleaux24/192 Music Downloads are Very Silly Indeed10:21
delinquentmedew we have anyone w extensive MD sim experience?10:24
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kanzurei have someone with inorganic chemistry simulation stuff10:27
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chris_99kanzure, do you have a folder of papers on sixth sense type stuff,  such as using electric stim of a tongue to 'see' etc.10:46
nmz787_ii have a folder on radio and biology10:49
nmz787_ii was looking for evidence of organs or experiments that postulated organs that could undertake such communication10:50
kanzurechris_99: not sorted http://diyhpl.us/~bryan/papers2/neuro/10:50
chris_99cheers10:50
nmz787_iclosest I came was finding some stuff on electric eel organs10:50
chris_99not sure i exactly get what you mean nmz787_i, what about the electric eel organs10:51
nmz787_iit's an organ that produces pulses of electricity, which is akin to how we do/have produced radio comms channels10:52
nmz787_ii.e. spark-gap transmitter in the old days10:52
chris_99dumb question how do they not shock themselves10:53
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nmz787_iso i was just studying the anatomy of the organs to see if there could be analogous structures in humans, or if there was enough plasticity in some neural sturctures to synthesize similar pulses10:53
nmz787_iI think it's cause they are the electrode10:54
chris_99aha10:54
nmz787_itheir whole body10:54
nmz787_iI could be wrong about that, but it's probably something about relative voltage at the least10:54
chris_99http://www.scientificamerican.com/article/how-do-electric-eels-gene/ <-- that doesn't really properly explain it, but it postulates10:56
eriduis there any citation manager for linux that will display citation counts from google scholar10:59
kanzurezotero probably does that10:59
kanzureit also toasts your bread10:59
eriduit doesn't seem like it does10:59
eriduit'll import "metadata" but I want live citation counts11:00
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nmz787_ichris_99: I don't seem to have the eel paper in my radio folder, but this looks like it might be the one i was reading years ago.... I remember gleaning that the organs basically were a diode-based voltage multiplier http://jgp.rupress.org/content/42/5/1067.full.pdf11:39
chris_99oh like whats it calld11:39
chris_99cockroft-walton circuit11:39
nmz787_ipaperbot: http://www.sciencedirect.com/science/article/pii/S1546509808600515?np=y11:40
kanzure"At this year’s annual meeting, Alcor reduced membership dues (for those not receiving discounts) by 10% and also waived the $180/year CMS fee for those with cryopreservation funding at least $20,000 over current minimums. For many members, that means a reduction in membership costs by $240 per year (31% reduction). The CMS waiver should be especially helpful to members young enough to get cheap life insurance. The cost of the extra ...11:41
nmz787_isomething like that, https://en.wikipedia.org/wiki/Voltage_multiplier11:41
paperbothttp://diyhpl.us/~bryan/papers2/paperbot/%0A%20Electric%20Organs%0A%20.txt11:41
kanzure... insurance will be very low for younger members, making the CMS waiver option attractive. Older members may find additional life insurance expensive or impossible to get. Many of these members will instead benefit from the new alternative funding policy. They will be able to use assets such as real estate, 401(k) plans, and bequests to fund up to half of their cryopreservation minimums. Overseas members, who can also enjoy lower costs from ...11:41
kanzure... the above changes, additionally benefit from the reduction in the overseas surcharge"11:41
nmz787_ipaperbot: http://www.sciencedirect.com/science?_ob=ShoppingCartURL&_method=add&_eid=1-s2.0-S1546509808600515&originContentFamily=serial&_origin=article&_ts=1410892881&md5=7ebed9e19105350a4b3dd5e637ec44b811:41
chris_99nmz787_i, http://en.wikipedia.org/wiki/Cockcroft%E2%80%93Walton_generator was the one i was thinking11:42
paperbothttp://diyhpl.us/~bryan/papers2/paperbot/38a82de081ec2953c6860eb52b2153c3.txt11:42
nmz787_iyep it's listed on the voltage multiplier page with similar circuits11:42
chris_99ah11:43
nmz787_ianyway here is the non-updated folder http://diyhpl.us/~nmz787/biological%20radio%20research/11:43
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kanzurepaperbot: https://eprint.iacr.org/2014/248.pdf12:44
kanzure"Fine grain Cross-VM Attacks on Xen and VMware are possible"12:45
paperbothttp://diyhpl.us/~bryan/papers2/paperbot/b94991daae95ec88d1348457a6a1865e.pdf12:45
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chris_99can one simply buy an electode array from somewhere out of interest13:23
chris_99*electrode13:24
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kanzureit's probably in a mcmaster catalog somewhere13:27
chris_99hmm maybe i could get one made somewhere - here's something like what i want https://tcnl.bme.wisc.edu/projects/completed/tdu to put on the tongue13:28
HEx2paperbot: http://www.nature.com/ncomms/2014/140121/ncomms4026/full/ncomms4026.html13:29
paperbothttp://libgen.org/scimag/get.php?doi=10.1038%2Fncomms402613:29
chris_99http://www.zachhoeken.com/mouthbrain13:32
nmz787_ithere's the thing out of uPitt13:33
nmz787_ithe MD (maybe MD/PhD) who was doing trials there was quite nice13:33
chris_99on tongue elctrodes?13:34
nmz787_iya13:35
chris_99i'm curious how they got a gold plated pcb13:35
chris_99for the electrodes13:35
chris_99would they plate copper13:35
chris_99i wonder13:35
nmz787_iask any rapper13:35
nmz787_ithey'll tell you how they get theirs13:36
chris_99lol13:36
chris_99i'll give that dude any email see where they fabbed it13:36
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chris_99got a reply apparently it's ENIG15:14
chris_99they used15:14
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chris_99i wonder how dense you could take the array15:16
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kanzure"New Organ, a collective initiative for tissue engineering and regenerative medicine, announced today the initial six teams competing for the New Organ Liver Prize, a global prize competition sponsored by the Methuselah Foundation, a biomedical charity. The prize challenge will award $1,000,000 to the first team that creates a regenerative or bioengineered solution that enables a large animal to live 90 days without native liver function."16:48
kanzure"Stephen Badylak (Team Badylak): A pioneer in biologic scaffolds using extracellular matrix"16:49
kanzure"Eric Lagasse (Team Ectogenesis): Grew mini-livers inside the lymph nodes of mice with liver disease."16:49
kanzure"Takanori Takebe (Team Organ Creative): Created tiny ‘liver buds’ that grew and functioned in mice."16:49
kanzure"Basak Uygun (Team HepaTx): First to report proof-of-principle transplantation of engineered liver grafts."16:49
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kanzure"As someone who works in the industry (but not Ticketmaster) and has spoken frequently to higher ups at TM, people should realize that the majority of the time "handling charges" are a way for performers to generate more revenue from sales while deflecting the bad PR to Ticketmaster. That's one of the services TM provides to their clients (performers/venues). If you're a performer and you want to sell tickets for a face value of "$50", but ...17:49
kanzure... generate revenue at the $60 or $65/ticket range, you add on some fees and let TM take the hit from the fans for "gouging" them. It's very common."17:49
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kanzure"I've started working with this guy who has a company called lab fellows which is trying to be the Uber or AirBnB of instruments.  He is setting up some stuff like HPLC.    But because these others are moving out of our lab and taking key equipment which we thought we'd have at least for another 6 months, now I have to buy a lot of things at one time.  "18:19
kanzure"I found multiple centrifuges like the one we are losing, ranging dramatically in price (BioSuprlus is $5700 with their "20% discount sale).  Ebay seems to be the best deal but I'm wary of buying some of these because I think there is likely something wrong or we'd end up having to fix it.  "18:19
kanzurehttp://www.ebay.com/itm/Sorvall-RC5C-Plus-Refrigerated-Floor-Centrifuge-w-SLA-1500-Super-Lite-Rotor-/371143816870?_trksid=p2054897.l567018:20
kanzurehttp://www.ebay.com/itm/like/181420025975?lpid=8218:20
dingoany startups that is the "something of something", where something's are other startups, is a fail in my book18:20
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kanzuredingo: i dunno man, i see a lot of promise in "uber of portable toilets"18:32
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yashgarothI'm still a little weirded out re shipping a centrifuge from the east coast18:45
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kanzureyashgaroth: whyso18:46
yashgarothirrational fear of mixing high-speed equipment and uncaring shipping people18:46
yashgarotha 40-pound rotor breaking free at 20,000g's and flying toward my face is one of many waking lab nightmares18:47
yashgarothbut the current one jojack has is some 80's 'fuge that only pulls 6,000g's so we do need something18:48
yashgarothI kinda felt like we only needed a benchtop sized one18:49
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kanzureso it should be disassembled before shiping?18:52
kanzureshipping18:52
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yashgarothcan't really disassemble it, but there's a lot of internal parts all kinda bolted together, some with tight tolerances18:54
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kanzurehm i see18:55
kanzurewell. see if someone is willing to do a roadtrip.18:56
yashgarothanyway this new salk professor is moving in November with "some equipment" so I feel like it'd be best to shop around locally until then18:56
yashgarothor roadtrip, but fuck what's the point of being in san diego if there's not surplus biotech equipment sitting in every alley18:57
kanzuregood point18:57
kanzuredon't you guys have a mafia or a gang or something by now18:57
yashgarothsssh18:57
yashgarothand it's tough to be all pink panther with a 600 pound heist18:58
kanzureexcuses18:58
kanzureso your company borrows time on the equipment?18:58
yashgarothI can't tell if it's that, or you pay them to run samples for you18:59
kanzureno i mean, were you saying royal we above or my company we18:59
kanzureabout needing a benchtop one18:59
yashgaroththe lab, in practical terms, isn't doing enough large-scale stuff to justify a high-speed floor 'fuge19:00
yashgarothas in, any two-person startup at BTnB19:00
yashgaroththough I don't doubt my own biases are clouding my judgment19:01
kanzurehm okay19:02
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yashgarothof course there's all kinds of weird edge cases; I don't know what any of the new tenants will be doing, and jojack doesn't know how to parse [what they do] into [how many g's they need to pull]19:04
kanzuredoes he have any lackeys?19:04
yashgarothwhat do you think he has, money?19:05
kanzureare you the only one19:05
yashgarothyeah p much19:05
kanzurehah19:05
kanzurehe's fucked19:05
kanzurei thought you were like, one of at least 1019:05
yashgarothheh, it's me, a large chasm, and then 20 people who are constantly angry and demanding things for free19:06
kanzureare the takers at least biology folk?19:06
yashgarothgenerally, yes; the lack of a fume hood wards off any chem people19:07
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kanzuredamn19:12
yashgarothfrankly I have no idea what anyone there really does, and since the two large "companies" are moving out, I'll have even less idea19:13
kanzureif you do things right nobody will know you have done anything at all19:13
kanzurehm i don't really have a centrifuge suggestion for him19:14
yashgarothI'm gonna pitch this http://surplus.ucsd.edu/Lot.aspx?id=9253519:14
kanzurei like how it's rocking the 2001 copyright date19:15
yashgarothdude they're an academic reseller, you can't imagine how lazy they are19:16
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kanzurehttp://dollar.fail/19:24
kanzure.title19:25
yoleauxOpen source P2P money19:25
kanzurenice redirect19:25
kanzurenot a bad offer https://www.sharelatex.com/github/19:46
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kanzure"However resellers are trying to maximize profits so maybe like $1800-2000? That's some game theory shit, I dunno."21:44
kanzuresuch advice21:44
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yashgarothI still think they have an agreement with biosurplus, like "ah this jojack has bid $2001, you'd have to bid...$2001, and perhaps a hundred more *cough*"21:52
kanzureget a mole at biosurplus21:52
kanzureor just walk in and ask21:52
kanzurepeople don't know how to do opsec21:52
yashgarothin my mind they're all infinitely corrupt so it shouldn't be hard21:52
kanzureput on a monocle and say you're from biosurplus and ask about your "special discount"21:53
yashgarothcough loudly while throwing 20s at them and maintaining eye contact21:53
kanzure"i was told there would be special considerations for myself and my bulky friend here"21:53
yashgarothtrue, we could literally just muscle in on their racket now that jojack's interested21:54
yashgarothwould be a shame if something were to happen to this glassware [casually drops graduated cylinder]21:54
yashgarothanyway, off to bed and dreams of shady backroom handoffs for rotary evaporators21:58
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kanzuresleep mode22:01
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ebowdenpaperbot: http://www.nature.com/neuro/journal/v16/n1/full/nn.3281.html23:09
paperbothttp://libgen.org/scimag/get.php?doi=10.1038%2Fnn.328123:09
ebowdenpaperbot: http://www.ncbi.nlm.nih.gov/pubmed/2357214523:14
paperbothttp://libgen.org/scimag/get.php?doi=10.1126%2Fscisignal.200394523:14
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--- Log closed Wed Sep 17 00:00:08 2014

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