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| kanzure | .title http://www.nature.com/nrmicro/journal/v8/n7/abs/nrmicro2392.html | 05:42 |
|---|---|---|
| yoleaux | Where microbiology meets microengineering: design and applications of reporter bacteria : Abstract : Nature Reviews Microbiology | 05:42 |
| kanzure | .title http://www.nature.com/nrmicro/journal/v8/n3/abs/nrmicro2262.html | 05:42 |
| yoleaux | A complex journey: transmission of microbial symbionts : Abstract : Nature Reviews Microbiology | 05:42 |
| kanzure | .title http://www.nature.com/nrmicro/journal/v11/n2/abs/nrmicro2937.html | 05:44 |
| yoleaux | Bacteriocins [mdash] a viable alternative to antibiotics? : Abstract : Nature Reviews Microbiology | 05:44 |
| kanzure | "legumes punish nonperforming nitrogen-fixing bacteria" | 05:45 |
| kanzure | .title http://onlinelibrary.wiley.com/doi/10.1111/j.1420-9101.2010.02114.x/full | 05:45 |
| yoleaux | The evolution of mutualism - LEIGH Jr - 2010 - Journal of Evolutionary Biology - Wiley Online Library | 05:45 |
| kanzure | .title http://onlinelibrary.wiley.com/doi/10.1111/j.1420-9101.2010.02084.x/full | 05:45 |
| yoleaux | The danger of applying the breeder's equation in observational studies of natural populations - MORRISSEY - 2010 - Journal of Evolutionary Biology - Wiley Online Library | 05:45 |
| kanzure | .title http://onlinelibrary.wiley.com/doi/10.1111/j.1558-5646.2010.01025.x/abstract | 05:48 |
| yoleaux | EARLY BURSTS OF BODY SIZE AND SHAPE EVOLUTION ARE RARE IN COMPARATIVE DATA - Harmon - 2010 - Evolution - Wiley Online Library | 05:48 |
| kanzure | .title http://onlinelibrary.wiley.com/doi/10.1111/j.1558-5646.2010.00959.x/abstract | 05:49 |
| yoleaux | NOVEL COOPERATION EXPERIMENTALLY EVOLVED BETWEEN SPECIES - Harcombe - 2010 - Evolution - Wiley Online Library | 05:49 |
| kanzure | .title http://onlinelibrary.wiley.com/doi/10.1111/j.1558-5646.2011.01444.x/abstract | 05:50 |
| yoleaux | DIRECTIONAL SELECTION IN TEMPORALLY REPLICATED STUDIES IS REMARKABLY CONSISTENT - Morrissey - 2011 - Evolution - Wiley Online Library | 05:50 |
| kanzure | .title http://www.nature.com/nature/journal/v467/n7313/abs/nature09342.html | 05:53 |
| yoleaux | Epigenetic memory in induced pluripotent stem cells : Nature : Nature Publishing Group | 05:53 |
| kanzure | "Here we observe that low-passage induced pluripotent stem cells (iPSCs) derived by factor-based reprogramming of adult murine tissues harbour residual DNA methylation signatures characteristic of their somatic tissue of origin, which favours their differentiation along lineages related to the donor cell, while restricting alternative cell fates. Such an ‘epigenetic memory’ of the donor tissue could be reset by differentiation and ... | 05:53 |
| kanzure | ... serial reprogramming, or by treatment of iPSCs with chromatin-modifying drugs. In contrast, the differentiation and methylation of nuclear-transfer-derived pluripotent stem cells were more similar to classical embryonic stem cells than were iPSCs. Our data indicate that nuclear transfer is more effective at establishing the ground state of pluripotency than factor-based reprogramming, which can leave an epigenetic memory of the ... | 05:54 |
| kanzure | ... tissue of origin that may influence efforts at directed differentiation for applications in disease modelling or treatment." | 05:54 |
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| kanzure | .title http://www.nature.com/nrmicro/journal/v12/n6/abs/nrmicro3262.html | 06:11 |
| yoleaux | The microbial ecology of permafrost : Nature Reviews Microbiology : Nature Publishing Group | 06:11 |
| kanzure | .title http://www.nature.com/nrmicro/journal/v11/n2/abs/nrmicro2939.html | 06:13 |
| yoleaux | Microbial life under extreme energy limitation : Abstract : Nature Reviews Microbiology | 06:13 |
| kanzure | "A great number of the bacteria and archaea on Earth are found in subsurface environments in a physiological state that is poorly represented or explained by laboratory cultures. Microbial cells in these very stable and oligotrophic settings catabolize 10^4 to 10^6 -fold more slowly than model organisms in nutrient-rich cultures, turn over biomass on timescales of centuries to millennia rather than hours to days, and subsist with energy ... | 06:14 |
| kanzure | ... fluxes that are 1,000-fold lower than the typical culture-based estimates of maintenance requirements. To reconcile this disparate state of being with our knowledge of microbial physiology will require a revised understanding of microbial energy requirements, including identifying the factors that comprise true basal maintenance and the adaptations that might serve to minimize these factors." | 06:14 |
| kanzure | cool | 06:14 |
| kanzure | "Other advances in sample collection have occurred outside of the conventional scientific ocean drilling programs that provide new opportunities for collecting deep biosphere samples. For example, revised giant piston coring devices for retrieval of longer (10 s of meters) sediment cores have been developed in both the USA (Røy et al., 2012) and France (Bourillet et al., 2007)." | 06:24 |
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| ebowden | http://icb.oxfordjournals.org/content/42/2/369.full | 06:34 |
| archels | .title | 06:35 |
| yoleaux | Partner Choice in Nitrogen-Fixation Mutualisms of Legumes and Rhizobia | 06:35 |
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| ebowden | http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0093670 | 06:45 |
| ebowden | .title | 06:50 |
| yoleaux | PLOS ONE: Evolutionary Dynamics of Nitrogen Fixation in the Legume–Rhizobia Symbiosis | 06:50 |
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| kanzure | hm | 09:03 |
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| kanzure | you guys are boring | 12:15 |
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| andytoshi | i met a biotech guy at a bar the other night and tried to get him to come here, but i doubt he knows how to use IRC | 13:46 |
| andytoshi | also told him to look you up | 13:46 |
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| chris_99 | http://digitalnature.slis.tsukuba.ac.jp/2015/06/fairy-lights-in-femtoseconds/ | 14:02 |
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| frant | hplus=transhumanism(human plus) | 14:24 |
| frant | ? | 14:24 |
| frant | what kind of hw/sw do you guys need? | 14:24 |
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| kanzure | frant: we need giant death rays and kilometer-wide sattelite clouds | 14:53 |
| chris_99 | haha | 14:58 |
| chris_99 | how hard would it be, to make coloured rain i wonder | 14:58 |
| kanzure | frant: also we need dna synthesis equipment | 15:01 |
| frant | im talking about lowhanging fruit | 15:06 |
| frant | cheap | 15:06 |
| frant | to help accelerate the process | 15:06 |
| frant | make things cheaper for you guys | 15:06 |
| frant | ill be back tomorrow | 15:06 |
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| kanzure | https://medium.com/starts-with-a-bang/ask-ethan-94-could-dark-matter-not-exist-de5cd810e446 | 16:32 |
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| nmz787_i | kanzure: those coasters could only be cooler if it was real brains | 16:56 |
| kanzure | we could probably do that | 16:57 |
| kanzure | slice a brain, then fixate it, then laminate it or put it between two pieces of plastic | 16:57 |
| nmz787_i | those microtome imaging startups could probably actually /make/ some $$$ with coasters like that versus real science | 16:59 |
| kanzure | yeah might be an interesting way to fund their work... but can't put that up on crowdstarter because it's animal matter. | 17:05 |
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| nmz787_i | kanzure: what dates are the recent DNA talks in? (dang I still didn't come up with a web-based grepper that isn't google) | 17:18 |
| nmz787_i | this shows 6 hits 'site:gnusha.org/logs/ 2015-06 dna' | 17:21 |
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| kanzure | http://gnusha.org/logs/2015-06-19.log | 17:33 |
| kanzure | http://gnusha.org/logs/2015-06-20.log | 17:33 |
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| nmz787_i | fenn: CaptHindsight immune cells modify their own DNA... look up VDJ recombination | 17:57 |
| nmz787_i | .wik VDJ recombination | 17:57 |
| yoleaux | "V(D)J recombination, less commonly known as somatic recombination, is the unique mechanism of genetic recombination that occurs only in developing lymphocytes during the early stages of T and B cell maturation." — https://en.wikipedia.org/wiki/VDJ_recombination | 17:57 |
| fenn | it's a very limited process | 18:15 |
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| kanzure | hmm | 19:02 |
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| CaptHindsight | nmz787: I was wondering how machinery can be supplied by nature vs me | 19:27 |
| kanzure | we should really get back to project "rob all the graves of all the dead smart people to extract their skeletal dna remains" | 19:37 |
| kanzure | e.g. some roadtrip | 19:37 |
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| kanzure | .title https://news.ycombinator.com/item?id=9798374 | 20:22 |
| yoleaux | Could dark matter not exist? | Hacker News | 20:22 |
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| --- Log closed Tue Jun 30 00:00:56 2015 | ||
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