| --- Log opened Fri Sep 04 00:00:00 2015 | ||
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| james4trek | Hello all. Hope to chat friendly-like with nanotechnologists and anyone who still talks about NanoEngineer. I read a log and found only stuff from 2012. Am I missing something, or has this channel moved onto another project? | 01:02 |
|---|---|---|
| james4trek | hm, I guess everyone might be asleep? | 01:04 |
| james4trek | I might have some free time now, so I was thinking about trying to help out. | 01:04 |
| james4trek | Anybody? Test, one two, three. | 01:05 |
| james4trek | Hm. Well, ... map props to Kanzure, whose exploits I read of this channel's log. :) I'm currently trying to get a chroot working for NanoEngineer. Maybe it's time for me to go to bed too. "Everyone else is doing it!" ... heh | 01:06 |
| justanotheruser | this channel doesn't talk about nanoengineer much | 01:08 |
| justanotheruser | I'm not sure this channel was ever dedicated to NE-1 either | 01:08 |
| james4trek | *sigh* ... Well, hopefully I can try a few things, and maybe get a pointer or too. Sadly, I think I'm about to succumb to the spectre of sleep. | 01:08 |
| justanotheruser | there's an occasional discussion though | 01:08 |
| james4trek | cool, cool | 01:08 |
| james4trek | thanks for the comment, JAU | 01:09 |
| justanotheruser | I too came here for NE-1, but kanzure likes to pretend he recruited me from #bitcoin | 01:09 |
| james4trek | heh | 01:10 |
| james4trek | I see. Maybe he wants to forget it. ;- ( I've been the "last" guy who knows something before. It sucks, even if it's a nice thing you know. | 01:10 |
| gradstudentbot | Well, that paper was actually retracted. | 01:10 |
| james4trek | * becomes entranced by the lights beneath the water, and follows them uh-oh ... | 01:11 |
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| justanotheruser | I don't think he minds discussing it though it doesn't seem to be a topic of interest of his, though he has mentioned wanting to pay some russians to refactor it | 01:18 |
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| kanzure | they quit the channel sorta hard to communicate with 'em | 05:37 |
| kanzure | mems lidar for self-driving horses http://pioneer.jp/en/news/press/2015/pdf/0901-1.pdf | 05:46 |
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| kanzure | http://diyhpl.us/~bryan/papers2/neuro/Why%20you%20are%20probably%20not%20a%20brain%20in%20a%20vat.pdf | 05:57 |
| justanotheruser | yes, my daily dose of ##hplus philosophy | 06:00 |
| kanzure | OP_COPY_SCRIPTSIG https://bitcointalk.org/index.php?topic=164655.msg1720098#msg1720098 | 06:02 |
| kanzure | gross, lifespan.io put an add in times square wtf | 06:11 |
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| kanzure | binary visualization for reverse engineering reasons https://github.com/wapiflapi/binglide http://binvis.io/ https://www.youtube.com/watch?v=4bM3Gut1hIk | 08:57 |
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| nmz787_w | is github on internet archive? | 10:14 |
| nmz787_w | or is there some github mirror-scraper? | 10:14 |
| nmz787_w | I was just looking at this repo a few days ago and now its gone... but I failed to clone it :/ https://github.com/dstegelman/lightweight-django-scrum | 10:14 |
| nmz787_w | oh, I guess I found some similar repos since it was based on a book example | 10:16 |
| kanzure | http://webcache.googleusercontent.com/search?q=cache:dbKDkfCiM1AJ:https://github.com/dstegelman/lightweight-django-scrum/commits/master+&cd=2&hl=en&ct=clnk&gl=us | 10:16 |
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| kanzure | probably from https://github.com/lightweightdjango/examples | 10:17 |
| kanzure | or https://github.com/whatsupdan/lightweight-django/tree/master/scrum-repo/scrum | 10:18 |
| nmz787_w | yeah | 10:18 |
| nmz787_w | I chose https://github.com/djangopractice/scrum | 10:18 |
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| james4trek | Show of hands, who's a bot? | 11:04 |
| kanzure | false question, bots don't have hands | 11:13 |
| nmz787_w | they can have 'handlers' | 11:16 |
| nmz787_w | or 'handles' | 11:16 |
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| delinquentme | i have a coffee grind balloon omnigripper nmz787 | 11:57 |
| delinquentme | i shove it into things then suck | 11:58 |
| delinquentme | on a call w the CSO from oxford biotherapeutics | 11:58 |
| delinquentme | let me know if anyone has specific questawns | 11:58 |
| gradstudentbot | I haven't written the abstract. | 11:59 |
| kanzure | delinquentme: ask them if they work with any CROs (if they contract out any of their services) and if so which services or how they handle that | 12:03 |
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| kanzure | delinquentme: also ask them if they know joseph jackson at biotechnbeyond in carlsbad | 12:03 |
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| kanzure | http://www.strengthandconditioningresearch.com/hypertrophy/ | 12:37 |
| delinquentme | sorry didnt ask | 12:42 |
| delinquentme | wasnt interesting question for him | 12:42 |
| delinquentme | also https://hackaday.io/post/2978 | 12:42 |
| delinquentme | for pee | 12:42 |
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| gradstudentbot | Can I borrow some sulphuric acid? | 12:44 |
| delinquentme | kanzure, trying to get consistent hypertrophy sucks. Had back day yesterday and im barely sore | 12:44 |
| kanzure | delinquentme: roids, man, roids. | 12:44 |
| delinquentme | 40 pullups and 200x reps of 190 | 12:44 |
| delinquentme | cooling glove also possible ... I've been meaning to run self-tests on water across my arms / legs / head though | 12:45 |
| delinquentme | i dont have persistent butthole thermometer | 12:45 |
| kanzure | such is life | 12:45 |
| delinquentme | you're aware of the cooling glove claims right kanzure ? that dropping core body temp was, in stanford words: "comparable to effects of steroids " | 12:45 |
| kanzure | no did not see | 12:46 |
| CaptHindsight | http://www.dtic.mil/dtic/tr/fulltext/u2/a004776.pdf Evaluation of a Water-Cooled Helmet Liner | 12:50 |
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| kanzure | gradstudentbot: https://xkcd.com/451/ | 12:56 |
| gradstudentbot | My pub of choice is pubmed. | 12:56 |
| delinquentme | gradstudentbot, I like yew | 12:58 |
| gradstudentbot | Blah, why won't they just kick me out. | 12:58 |
| delinquentme | kanzure, thats awesome. | 12:59 |
| CaptHindsight | only 4 minutes for Sociology? | 13:00 |
| kanzure | engineering would be like a few seconds at most.. maybe a few milliseconds. they just know. they can sense it. | 13:01 |
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| nsh | -- | 13:58 |
| nsh | Many attempts have been made to understand the origin of life and biological complexity both at the experimental and theoretical levels but neither is fully explained. In an influential work, Maynard Smith and Szathmáry (1995) argued that the majority of the increase in complexity is not gradual, but it is associated with a few so-called major transitions along the way of the evolution of life. For each major transition, they identified specific mechanism | 13:58 |
| nsh | s that could account for the change in complexity related to information transmission across generations. In this work, I propose that the sudden and unexpected improvement in the functionality of an organism that followed a major transition was enabled by a phase transition in the network structure associated with that function. The increase in complexity following a major transition is therefore directly linked to the emergence of a novel structure–fun | 13:58 |
| nsh | ction relation which altered the course of evolution. As a consequence, emergent phenomena arising from these network phase transitions can serve as a common organizing principle for understanding the major transitions. As specific examples, I analyze the emergence of life, the emergence of the genetic apparatus, the rise of the eukaryotic cells, the evolution of movement and mechanosensitivity, and the emergence of consciousness. Finally, I discuss the im | 13:58 |
| nsh | plications of network associated phase transitions to issues that bear relevance to the history, the immediate present and perhaps the future, of life. | 13:58 |
| nsh | -- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3322530/ | 13:58 |
| delinquentme | kanzure, | 14:00 |
| delinquentme | do you advertise as a hard tech consultant ? | 14:00 |
| delinquentme | you should. | 14:00 |
| kanzure | "technology consultant wizard dude" | 14:01 |
| kanzure | close enough? | 14:01 |
| kanzure | i can mock up some force lightning if that will help | 14:01 |
| kanzure | nsh: yes yes, there's various stu kauffman stuff about punctuated equilibrium in complex dissipative systems | 14:02 |
| nsh | right | 14:02 |
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| delinquentme | someone made an interesting statement in comparing the stability of biological systems to those of typical chemical systems at very low temps | 14:09 |
| delinquentme | was an interesting observation | 14:09 |
| delinquentme | esp considering the stability / difference of complexity | 14:09 |
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| delinquentme | kanzure, who in here could get me bulk pricing on FBS ? | 14:15 |
| kanzure | fbwho? | 14:18 |
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| delinquentme | fecal bovine serum | 14:21 |
| delinquentme | lulz no fetal bovine serum | 14:21 |
| delinquentme | used for growth factors in human cell line rearing to get them to gogogogogogogrowth | 14:22 |
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| drethelin | often used in 10 percent amounts | 14:26 |
| drethelin | delinquentme: why are you shopping in here | 14:26 |
| drethelin | for a standard laboratory product | 14:27 |
| drethelin | you know who could probably get you bulk prices? a bulk distributor like fisher | 14:27 |
| drethelin | http://www.omegascientific.com/ top hit on google for bulk fetal bovine serum | 14:27 |
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| kanzure | drethelin: actually, gradstudentbot resells basic reagents because we don't pay him enough | 14:28 |
| gradstudentbot | How many papers do you have published? | 14:28 |
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| delinquentme | drethelin, because looking for like 1/10th the price | 14:29 |
| delinquentme | I need to know how little I can pay to start cell line werk | 14:30 |
| delinquentme | plz donate | 14:30 |
| kanzure | steal some from john schloendorn isn't he down the street from you | 14:30 |
| drethelin | just buy a cow | 14:31 |
| drethelin | and draw your own cow blood | 14:31 |
| drethelin | I could ask my dad if you want | 14:34 |
| drethelin | he might know a cheap source | 14:34 |
| drethelin | he's pretty thrifty about lab supplies | 14:35 |
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| delinquentme | drethelin, yeah if you think he might have significantly cheaper FBS | 14:45 |
| delinquentme | absoroot rey | 14:45 |
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| drethelin | I dunno | 14:53 |
| drethelin | we might just pay retail for it | 14:53 |
| drethelin | since we don't use lot | 14:53 |
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| delinquentme | i've picked up a new trick when recruiters try to get me on the phone: | 15:04 |
| delinquentme | " I make it a point to not take extra phone calls until we know theres real possibility for a hire. " | 15:04 |
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| kanzure | delinquentme: "In the mean time you can talk with my assistant over the phone, but her assistant might have to schedule you for later next week. Is that OK?" | 15:09 |
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| delinquentme | ^^^^ | 15:25 |
| kanzure | "We can always sign my standard agreement immediately, which offers you a flexible <insert wording> paid at a reasonable $3k per 8 hour reserved block." | 15:28 |
| kanzure | https://www.kernel.org/doc/Documentation/CodingStyle | 15:33 |
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| mgin | $3k per day? not bad | 16:01 |
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| delinquentme | drethelin, let me know if you can get cheaper than $250 / 500mL | 17:22 |
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| kanzure | .title http://link.springer.com.sci-hub.org/article/10.1007/s10508-015-0516-2 | 18:08 |
| kanzure | 1K4t2vSBSS2xFjZ6PofYnbgZewjeqbG1TM | 18:08 |
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| kanzure | .title http://www.nature.com/mp/journal/vaop/ncurrent/full/mp2015108a.html | 18:39 |
| yoleaux | Molecular Psychiatry - A genome-wide analysis of putative functional and exonic variation associated with extremely high intelligence | 18:39 |
| kanzure | "Although individual differences in intelligence (general cognitive ability) are highly heritable, molecular genetic analyses to date have had limited success in identifying specific loci responsible for its heritability. This study is the first to investigate exome variation in individuals of extremely high intelligence. Under the quantitative genetic model, sampling from the high extreme of the distribution should provide increased ... | 18:40 |
| kanzure | ... power to detect associations. We therefore performed a case–control association analysis with 1409 individuals drawn from the top 0.0003 (IQ >170) of the population distribution of intelligence and 3253 unselected population-based controls. Our analysis focused on putative functional exonic variants assayed on the Illumina HumanExome BeadChip. We did not observe any individual protein-altering variants that are reproducibly ... | 18:40 |
| kanzure | ... associated with extremely high intelligence and within the entire distribution of intelligence. Moreover, no significant associations were found for multiple rare alleles within individual genes. However, analyses using genome-wide similarity between unrelated individuals (genome-wide complex trait analysis) indicate that the genotyped functional protein-altering variation yields a heritability estimate of 17.4% (s.e. 1.7%) based on ... | 18:40 |
| kanzure | ... a liability model. In addition, investigation of nominally significant associations revealed fewer rare alleles associated with extremely high intelligence than would be expected under the null hypothesis. This observation is consistent with the hypothesis that rare functional alleles are more frequently detrimental than beneficial to intelligence." | 18:40 |
| kanzure | heh zip files committed to git | 18:41 |
| kanzure | perhaps there are other aspects of cognitive ability that iq does not measure that might be more strongly genetically correlated, like working memory set size | 18:43 |
| kanzure | .wik PLXNB2 | 18:44 |
| yoleaux | "Plexin-B2 is a protein that in humans is encoded by the PLXNB2 gene." — https://en.wikipedia.org/wiki/PLXNB2 | 18:44 |
| kanzure | "Members of the B class of plexins, such as PLXNB2 are transmembrane receptors that participate in axon guidance and cell migration in response to semaphorins (Perrot et al. (2002)).[supplied by OMIM][3]" | 18:44 |
| kanzure | "In addition, a specific cognitive ability missing from this study, spatial ability, should be added to the mix because spatial ability predicts occupational and creative accomplishments beyond quantitative and verbal reasoning abilities.51, 52" | 18:46 |
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| kanzure | .title https://www.youtube.com/watch?v=Lu9dUG3_KNA | 19:41 |
| yoleaux | STAR WARS EP 4: Laser Moon Awakens - YouTube | 19:41 |
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| kanzure | hmph | 22:19 |
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| JayDugger | Good morning, everyone. | 22:37 |
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| --- Log closed Sat Sep 05 00:00:01 2015 | ||
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