| --- Log opened Thu Sep 17 00:00:30 2015 | ||
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| kanzure | http://www.brainpreservation.org/ken-hayworths-personal-response-to-mit-technology-review-article/ | 04:10 |
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| kanzure | "The hybrid protein combines a photoreceptor protein called cryptochrome 2 (Cry2) from a small, flowering plant Arabidopsis thaliana with the STromal Interaction Molecule 1 (STIM1), a protein found in almost all animals that opens cellular Ca2+ channels. They named the resultant hybrid molecule OptoSTIM1. When they shined blue light on the OptoSTIM1-expressing cells, they were able to coax them to open their Ca2+ channels and allow an ... | 04:15 |
| kanzure | ... influx of 5 to 10 times more Ca2+ than in previous studies." | 04:15 |
| kanzure | .title http://www.nature.com/nbt/journal/vaop/ncurrent/full/nbt.3350.html | 04:16 |
| yoleaux | Optogenetic control of endogenous Ca2+ channels in vivo : Nature Biotechnology : Nature Publishing Group | 04:16 |
| kanzure | http://www.kurzweilai.net/new-optogenetics-process-could-lead-to-neurological-enhancements-and-treatments | 04:16 |
| kanzure | .title http://www.sciencemag.org/content/349/6253/1216 | 04:16 |
| yoleaux | Tuning of fast-spiking interneuron properties by an activity-dependent transcriptional switch | 04:16 |
| kanzure | .title http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1002238 | 04:17 |
| yoleaux | PLOS Biology: A Change in the Ion Selectivity of Ligand-Gated Ion Channels Provides a Mechanism to Switch Behavior | 04:17 |
| kanzure | igem presentations will be recorded this year for once | 04:18 |
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| kanzure | "Let's say we build a series of large mirrors and possibly Fresnel lenses and send them into space in the direction of a planned ship cruise. Then we send the sail ship, followed by a series of lenses focusing the laser beam on the ship until midway to target, at maximum acceleration, and then switch to the mirrors ahead of it, to effect deceleration. The mirrors eventually crash into the target star or perhaps are left to sail forever ... | 06:09 |
| kanzure | ... but the ship is rapidly slowed down to reach target in the shortest time." | 06:09 |
| kanzure | "This is very similar to the Landis interstellar lightsail model. You use a big sail to accelerate, then detach it and use it as a mirror to slow the payload section that has a smaller center lightsail. The lenses only allow you to accelerate very efficiently for longer, they are unlikely to be helpful near the destination. However, sacrificial lenses and sails make for good SETI targets." | 06:09 |
| kanzure | "In my "spamming the universe" scheme I looked at enormous coilguns, essentially a Dyson sphere with light-second long coilguns (a Dyson urchin?) since they also get around the rocket equation. Eric D pointed out that lasers would be even more effective, and the lens trick could allow focused acceleration for a surprisingly long time." | 06:09 |
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| kanzure | someone should test k12 education vs. frontal lobe lobotomies | 07:03 |
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| CaptHindsight | lobotomies don't include the social engineering | 07:46 |
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| JayDugger | test the effects on students or on the teachers and administrators? | 08:20 |
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| chris_99 | kanzure, how do i leave a message for someone on 'ere? | 08:25 |
| kanzure | chris_99: use .tell username message | 08:27 |
| chris_99 | cheers | 08:27 |
| chris_99 | .tell nmz787 http://www.peachyprinter.com/#!peachy-printer-kit/c1uoo | 08:27 |
| yoleaux | chris_99: I'll pass your message to nmz787. | 08:27 |
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| juri_ | does anyone know what's up with the data science tool kit? | 12:29 |
| erasmus | yes | 12:37 |
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| juri_ | do they mind telling me? :P | 12:40 |
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| nmz787_w | chris_99: cool! I've seen that before, but too bad they're still only taking pre-orders | 12:52 |
| chris_99 | yeah it looks like it was created on kickstarter late 2013 alas | 12:52 |
| chris_99 | but looks interesting nonetheless | 12:52 |
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| superkuh | A friend of mine went in for that kickstarter. He'll be happy to see actual progress. | 13:00 |
| chris_99 | im awaiting for a spectrometer kickstarter, which also seems very slow in updates | 13:00 |
| kanzure | you mean nmz787's? | 13:03 |
| chris_99 | nah, https://www.kickstarter.com/projects/903107259/scio-your-sixth-sense-a-pocket-molecular-sensor-fo | 13:03 |
| chris_99 | which is probably a waste of money now i've learned more | 13:03 |
| chris_99 | i should have got one like nmz787_w has | 13:04 |
| nmz787_w | seems like the killer spectrometer will be something with optical heterodyning and a variable laser to scan the frequencies of interest | 13:15 |
| chris_99 | variable lasers sound nifty i only heard of them not too long ago | 13:18 |
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| ryankarason | :o.. a pocket spectrometer would be awesome | 13:33 |
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| nmz787_w | kanzure: I'm guessing you've heard of this https://www.braintreepayments.com | 14:01 |
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| kanzure | i thought they were acquired by paypal | 14:17 |
| kanzure | ah yes. | 14:18 |
| kanzure | anyway, see also stripe | 14:18 |
| nmz787_w | does stripe take bitcoin too? | 14:21 |
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| kanzure | yes stripe has a bitcoin feature | 14:31 |
| nmz787_w | from the quick look at braintree, bitcoin takes more setup with something called coinbase... so it's not ready to use with just signing up for braintree | 14:35 |
| kanzure | coinbase has payment processing things like bitpay | 14:39 |
| kanzure | and a consumer-oriented web wallet | 14:39 |
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| justanotheruser | Do genetic engineers wear designer genes? | 14:54 |
| nmz787_w | justanotheruser: Probably not on purpose... them there genes are expensive... they might spill some genes on themselves once in a while | 14:55 |
| * nmz787_w don't spill the beans /or/ genes | 14:55 | |
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| TMA | justanotheruser: of course they do. If I recall correctly the gene engineer introduces the genes to the target creature using gene gun, that shoots some nanoparticles with genes tacked on. They hold the gun in one hand and the target in the other. Some of the particles miss (or go through) and hit the other hand :) | 15:13 |
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| kanzure | http://www.devttys0.com/2015/04/what-the-ridiculous-fuck-d-link/ | 17:01 |
| justanotheruser | why isn't ralph merkle in this channel | 17:25 |
| kanzure | because he's a meanie butthead and is too busy pandering to ethereum | 17:31 |
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| JayDugger | Heh. | 17:35 |
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| kanzure | yashgaroth: yo | 18:16 |
| yashgaroth | hoi | 18:16 |
| kanzure | sup | 18:16 |
| yashgaroth | put in my 2 weeks' at my job today | 18:16 |
| kanzure | where you headed | 18:17 |
| yashgaroth | nowhere in particular, just free agenting for a little while | 18:17 |
| kanzure | have you finally decided that my nootropics plan is the best idea ever? | 18:17 |
| yashgaroth | is the plan "do a bunch of nootropics"? | 18:17 |
| kanzure | toxo | 18:18 |
| yashgaroth | it's on the list somewhere | 18:18 |
| kanzure | well if you have crazy projects and want more resources hit me up | 18:18 |
| yashgaroth | yeah I can likely do some work on the oligo ligase investigation, and want to write up the follistatic-Fc in yeast project to the point where I can actual start lab work on it | 18:19 |
| kanzure | how do you feel about doing mouse work | 18:20 |
| yashgaroth | how intimate am I being with these mice | 18:20 |
| kanzure | that's at your discretion | 18:21 |
| yashgaroth | keeping mice is one thing, and note that I'd probably be doing it at joseph's lab so I can't be like throwing their brains everywhere | 18:21 |
| kanzure | ah that's unfortunate | 18:22 |
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| yashgaroth | yeah it's really the best part about mice, brain throwin' | 18:22 |
| yashgaroth | the lab is becoming less and less of a reason to remain in san diego since jojack keeps getting rid of equipment, like he's getting into the functional equipment now, I'm worried | 18:23 |
| yashgaroth | I'm fixing up the FPLC for the guy he sold it to, it's bittersweet | 18:24 |
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| streety | mouse work can be productive, not sure about this brain throwing though | 19:14 |
| yashgaroth | it's optional but entertaining | 19:16 |
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| streety | I prefer other organs. Although I was reading an interesting article today on tissue clearing for microscopy that was in the brain | 19:17 |
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| maaku | pretty confident that it was ethereum / stellar that was pandering to merkle | 21:32 |
| maaku | kanzure: but was there history to the meanie butthead comment? | 21:32 |
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| --- Log closed Fri Sep 18 00:00:31 2015 | ||
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