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| kanzure | hm. | 05:45 |
|---|---|---|
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| kanzure | docl: oh you know QuantumG. cool. | 07:41 |
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| kanzure | "Superintelligence cannot be contained: Lessons from computability theory" https://arxiv.org/abs/1607.00913 | 07:45 |
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| sebboh | hi kanzure, your contact page on fairlystable lead me here. | 10:33 |
| kanzure | what's up. | 10:34 |
| sebboh | I'm a new user. :) | 10:34 |
| kanzure | of course you are | 10:34 |
| kanzure | hi | 10:34 |
| sebboh | Made a repo named doer. Hi. So, great service, thank you. | 10:35 |
| kanzure | i'm merely a user on the site | 10:35 |
| kanzure | jrayhawk is the site operator | 10:35 |
| kanzure | blame him | 10:35 |
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| sebboh | ohh! Well hi jrayhawk_! See above... :) Anybody see anything wrong or expensive about my use so far? Can I get a heads up if I'm doing anything wrong or if the site is going to go down or something? :) | 10:37 |
| gradstudentbot | Is there free food at that seminar? | 10:37 |
| sebboh | also while I'm here, a question... you folks know that group of people called OpenBCI? They have a kickstarter for some EEG rig.. Would you buy one from them or should I look elsewhere? | 10:41 |
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| kanzure | https://blog.angel.co/dr-jenny-rooke-on-the-biggest-life-sciences-investment-shes-made-in-20-years/ | 11:01 |
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| jrayhawk_ | sebboh: Nah, you'd have to eat up several gigs before I noticed enough to care. | 14:32 |
| gradstudentbot | Can I take a nap yet? | 14:33 |
| jrayhawk_ | Oh hey, templates for that broke again. Ugh. | 14:33 |
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| sebboh | templates for what? I had a hard time changing a template today until I just git clone the whole thing and wrote one. Easy, then. :) | 14:37 |
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| jrayhawk_ | Main page templates. "Preferences", in particular, is useless and supposed to be disabled. | 14:38 |
| sebboh | btw the piny on piny.be has ikiwiki 3.20141016. | 14:39 |
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| jrayhawk_ | That is an excellent point. | 14:39 |
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| sebboh | what are the odds that anybody's site will break? (Mine won't or if it does I don't care, hardly anything there!) | 14:41 |
| gradstudentbot | The results of my study indicate that the climate is about to get really weird. | 14:41 |
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| sebboh | btw sorry all for taking over conversation in here. :) Any better place? Not that this isn't lovely, I just don't want to be rude (more). | 14:42 |
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| jrayhawk_ | I'm actually a little confused about how you associated Kanzure's name with fairlystable | 14:43 |
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| jrayhawk_ | But up to him if he cares. To some extent people tricking me into working on piny benefits him since he's using it on his servers. | 14:43 |
| sebboh | oh I just did a site: google search and he's got his contact info on there somewhere, it was actually kinda a blunder for me to assume he was admin! | 14:44 |
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| sebboh | s/kinda// | 14:44 |
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| kanzure | oh so it is... weird. | 14:51 |
| sebboh | :) | 14:52 |
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| jrayhawk_ | Oh that's right, all those aliases exist for migration purposes. I guess I should 301 those back over to the proper places. | 14:57 |
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| justan0theruser | they gave me a crazy quote for the curved linear track | 16:22 |
| justan0theruser | $5k-$10k | 16:22 |
| kanzure | "sounds like you are in the wrong business" | 16:25 |
| justan0theruser | I think I'll just make a hack with a non-geared curved linear track | 16:31 |
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| kanzure | someone points out that scurvy is missing from http://diyhpl.us/wiki/genetic-modifications/ | 17:52 |
| justan0theruser | grubhub is down | 17:58 |
| CaptHindsight | justan0theruser: automation components are not in the same price range as openbuilds, reprap and ChinaCo ballscrews and linear bearings | 18:08 |
| CaptHindsight | https://www.aliexpress.com/w/wholesale-cnc-linear-rail.html maybe you can find a supplier that doesn't assemble their crunchy bearings on a dirt floor | 18:10 |
| kanzure | "Ascorbic acid as a sensor of oxidative stress and a regulator of gene expression: The Yin and Yang of vitamin C" http://www.medical-hypotheses.com/article/S0306-9877(07)00159-4/abstract | 18:12 |
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| kanzure | ForrestFlanagan: greets | 18:13 |
| kanzure | ForrestFlanagan: you should add things to http://diyhpl.us/wiki/genetic-modifications/ | 18:13 |
| kanzure | there's probably many things missing from there these days, it's been more than a year since that page was updated | 18:13 |
| ForrestFlanagan | I'll just allay my train of thought in the chat right here | 18:13 |
| ForrestFlanagan | I was in the process of finding the edit for re-enabling vitamin c synthesis in primates | 18:14 |
| ForrestFlanagan | and I started finding evolutionary papers theorizing about how the initial mutation conveyed enough advantage to be conserved | 18:15 |
| ForrestFlanagan | and it got me thinking that maybe fixing vitamin c synthesis would convey more risk than benefit with modern diets by disrupting useful biological signaling pathways | 18:16 |
| ForrestFlanagan | or maybe 'modern diets' bodge things up so much that it doesn't really matter, but my point is there's an element of risk | 18:16 |
| ForrestFlanagan | I'm currently reading this paper http://dx.doi.org/10.1016/j.mehy.2007.02.008 | 18:17 |
| ForrestFlanagan | .title | 18:17 |
| yoleaux | ForrestFlanagan: Sorry, that doesn't appear to be an HTML page. | 18:17 |
| ForrestFlanagan | Ascorbic acid as a sensor of oxidative stress and a regulator of gene expression: The Yin and Yang of vitamin C | 18:17 |
| ForrestFlanagan | why do they use yin and yang in the title | 18:18 |
| ForrestFlanagan | the authors are italians | 18:18 |
| ForrestFlanagan | in italy | 18:18 |
| kanzure | eh, you could probably do basic metabolic testing to determine whether that disruption would occur | 18:20 |
| kanzure | like with tissue culture | 18:20 |
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| ForrestFlanagan | there's a thing called transcription factor HIF1-alpha | 18:30 |
| ForrestFlanagan | it's inhibited if ascorbic acid is around | 18:30 |
| ForrestFlanagan | if ascorbic acid is used up, it activates a bunch of genes real hard | 18:31 |
| ForrestFlanagan | still looking those up | 18:31 |
| ForrestFlanagan | but there's a link between megadosing on vitamin c and cancer getting worse | 18:32 |
| ForrestFlanagan | and additionally, one of the things transcription factor HIF1-alpha activates has to do with making new blood vessels | 18:32 |
| ForrestFlanagan | but I think it'd be a bad thing if cancer got more blood vessels | 18:33 |
| ForrestFlanagan | there must be something I'm not getting | 18:33 |
| kanzure | it's not easy to tell the regulatory effects of increasing or decreasing cellular metabolism like this | 18:33 |
| kanzure | it's true thta megadosing can have negative effects, but that's not the same as hacking metabolism to express vitamin c | 18:33 |
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| ForrestFlanagan | well sure | 18:35 |
| ForrestFlanagan | the HIF stands for hypoxia-inducible factor, btw | 18:35 |
| ForrestFlanagan | it requires four things to be inhibited | 18:36 |
| ForrestFlanagan | oxygen, iron, vitamin C, and 2-oxo-glutarate | 18:36 |
| ForrestFlanagan | if any one drops, it starts promoting a bunch of genes that I'm still looking into | 18:37 |
| ForrestFlanagan | but I found a paper about it's activity when the oxygen level drops | 18:37 |
| ForrestFlanagan | in healing lung injuries | 18:37 |
| kanzure | yes there's lots of weird low-oxygen tissue preservation things out there.. | 18:38 |
| ForrestFlanagan | point is fixing it is likely to shake some complicated stuff up, the exact effects may be unnoticed until it's widely implemented | 18:41 |
| ForrestFlanagan | might increase certain cancer risks, might also make it harder to gain weight, would definitely influence food cravings | 18:42 |
| ForrestFlanagan | eh, I'll find the edit that fixes it for the wiki, I just want to put it out there that fixing really old damage in an evolved system can disrupt potentially useful things that appeared in the meantime | 18:44 |
| ForrestFlanagan | also it's way easier to find the region that humans lost vs the primates that codes for penis spines | 18:45 |
| ForrestFlanagan | just throwing that out there | 18:45 |
| ForrestFlanagan | it's maybe the largest region humans don't have that chimps do | 18:46 |
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| kanzure | wiki edits would be cool | 18:52 |
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| ForrestFlanagan | http://www.ca5.uscourts.gov/opinions/pub/15/15-50759-CV0.pdf Defense Distributed lost again in their ITAR vs 3D printing files case | 18:58 |
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| kanzure | oh interesting. | 18:59 |
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| ForrestFlanagan | potentially at stake: any open technical data that could be interpreted as pertaining to a weapon | 18:59 |
| ForrestFlanagan | potentially, interpretations could be stretched out to the point of being silly | 19:00 |
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| kanzure | right. well, i guess we'll go back to printing cryptography on t-shirts. | 19:03 |
| ForrestFlanagan | fortunately, their current stuff is available in the fosscad torrent | 19:03 |
| ForrestFlanagan | you could also try publishing crypto as a book | 19:04 |
| kanzure | adam back published crypto using a perl 3-liner on a t-shirt | 19:04 |
| ForrestFlanagan | I've got a friend that bought the PGP source code as a book when it looked like it was going to be outlawed | 19:04 |
| kanzure | back when crypto was classified as "military-grade munition" (actually it still is?) | 19:05 |
| ForrestFlanagan | perl 3 liner can't be that great for crypto? | 19:05 |
| ForrestFlanagan | what is is some kind of cipher? | 19:05 |
| ForrestFlanagan | I take that right back | 19:06 |
| kanzure | hm the dissent in that pdf is interesting | 19:07 |
| justan0theruser | I'm asking an indian company right now | 19:09 |
| ForrestFlanagan | the thing is itar doesn't apply to things like shitty toy pepperbox pistols | 19:09 |
| kanzure | mostly we run into ITAR problems because missiles and space tech :( | 19:10 |
| ForrestFlanagan | if it did I could get in trouble for just telling some foreign guy that a 3/4 inch steel gas pipe is a great fit for a 12 ga shell | 19:10 |
| ForrestFlanagan | "Indeed, the State Department has explicitly taken the position in this litigation and in a June 2015 Notice of Proposed Rulemaking that an individual wishing to place technical data in the public domain must obtain State Department approval." | 19:13 |
| ForrestFlanagan | oh snap, lock down ye git | 19:13 |
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| ForrestFlanagan | you need to ask john kerry permission | 19:14 |
| ForrestFlanagan | heck, this chat is logged and public | 19:14 |
| kanzure | yep | 19:15 |
| ForrestFlanagan | the texas state dept should know, according to their 2015 notice of proposed rulemaking | 19:15 |
| kanzure | but that's okay- there's already terrible things in the logs, you can't make it much worse | 19:15 |
| kanzure | virus manufacturing, uploading everyone and torturing billions of simulations for eternity, grey goo accidents, etc.... what's the worst that could happen. meh. | 19:15 |
| ForrestFlanagan | actually maybe the state dept is monitoring all the hplusroadmap code repositories | 19:18 |
| ForrestFlanagan | nah, that would imply there's some kind of intelligent resource allocation in texas | 19:18 |
| kanzure | we have also discussed methods of destroying various celestial bodies such as the earth and various moons-- although nobody seems particularly concerned about this *shrug* | 19:19 |
| ForrestFlanagan | oh, I like the idea of electromagnetic star lifting | 19:20 |
| ForrestFlanagan | just juice a star like an orange | 19:20 |
| kanzure | links? | 19:20 |
| ForrestFlanagan | I can probably dig some up | 19:21 |
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| ForrestFlanagan | In leiu of chapter four of David Criswell's book: https://en.wikipedia.org/wiki/Star_lifting | 19:28 |
| kanzure | .wik star lifting | 19:28 |
| yoleaux | "Star lifting is any of several hypothetical processes by which a sufficiently advanced civilization (specifically, one of Kardashev-II or higher) could remove a substantial portion of a star matter for any number of purposes. The term appears to have been coined by David Criswell." — https://en.wikipedia.org/wiki/Star_lifting | 19:28 |
| ForrestFlanagan | seti types look for it | 19:28 |
| kanzure | http://diyhpl.us/~bryan/papers2/physics/astrophysics/black-holes/Black%20holes:%20attractors%20for%20intelligence%3f.pdf | 19:29 |
| ForrestFlanagan | I know that paper | 19:29 |
| kanzure | http://diyhpl.us/~bryan/papers2/physics/astrophysics/Starivore%20extraterrestrials%20-%20Interacting%20binary%20stars%20as%20macroscopic%20metabolic%20systems%20-%20Clement%20Vidal.pdf | 19:29 |
| ForrestFlanagan | one of criswell's ideas is to use stimulated mass ejection from stars to create gas giants for storing hydrogen and helium | 19:31 |
| ForrestFlanagan | there's also application in mining the heavier stuff from stars, but I can't find a digital copy of the book | 19:33 |
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| ForrestFlanagan | anyways, star lifting goes hand in hand with any considerable sized dyson cloud | 19:34 |
| ForrestFlanagan | just turn down the magnetic repulsion on your statites and drift toward the star for a bit | 19:35 |
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| ForrestFlanagan | then turn the whole cloud on at once, full blast | 19:35 |
| ForrestFlanagan | and you get the "everyone on the equator just jumped at the same time" effect | 19:36 |
| ForrestFlanagan | and then hopefully you've got a plan for steering the coronal mass ejection | 19:36 |
| kanzure | ForrestFlanagan: did you see the madeinspace transcript recently? http://diyhpl.us/wiki/transcripts/niac-2016/reconstituting-asteroids-into-mechnical-automata/ | 19:37 |
| kanzure | and also http://diyhpl.us/wiki/transcripts/seti-megastructures-jason-wright-2016/ | 19:37 |
| ForrestFlanagan | that's interesting | 19:39 |
| ForrestFlanagan | wait I've seen the seti megastructures talk | 19:39 |
| ForrestFlanagan | it was in your transcripts, It must have come up previously | 19:40 |
| ForrestFlanagan | I want to see cyclotrons in space | 19:40 |
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| ForrestFlanagan | specifically free electron lasers | 19:41 |
| ForrestFlanagan | they just need power and vacuum, space has plenty of that | 19:41 |
| kanzure | i'll get right on it. | 19:42 |
| kanzure | ForrestFlanagan: ok how about http://diyhpl.us/~bryan/papers2/optics/Orbiting%20rainbows%20-%20optical%20manipulation%20of%20aerosols%20and%20the%20beginnings%20of%20future%20space%20construction%20-%20NASA.pdf | 19:42 |
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| ForrestFlanagan | that looks like it'd shit up radio, terrestrial astronomy, etc | 19:43 |
| ForrestFlanagan | on first glance | 19:43 |
| kanzure | depends on where and how you deploy it | 19:44 |
| kanzure | presumably you would use very isolated aerosol clumps | 19:44 |
| kanzure | rather than adding a stupid ring to the planet | 19:44 |
| ForrestFlanagan | it's using laser pressure containment early on | 19:45 |
| ForrestFlanagan | in an optically fucky medium | 19:45 |
| kanzure | ya | 19:45 |
| kanzure | well it's optical pressure to push things back into the right places, but not always-on | 19:45 |
| ForrestFlanagan | btw | 19:46 |
| ForrestFlanagan | that's a way to do a demonpore, right? | 19:46 |
| ForrestFlanagan | optical pressure? | 19:46 |
| kanzure | optical traps are really bulky and annoying to setup | 19:46 |
| ForrestFlanagan | I've been puzzling over materials, but it occurs that maybe demonpores are just a refinement on optical traps? | 19:47 |
| kanzure | .title https://www.youtube.com/watch?v=c3kMjXAe6FU | 19:47 |
| yoleaux | Optical tweezer setup - YouTube | 19:47 |
| kanzure | that's not as bad as i remember | 19:48 |
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| ForrestFlanagan | just guessing, I think they're interesting and it bothered me that I couldn't think of a straightforward way to make ultra cheap and simple demonpores | 19:48 |
| ForrestFlanagan | I mean, they'd have to be cheap and simple if I'm to have half a dozen of them in my bathrooms analyzing my various fluids | 19:50 |
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