--- Day changed Thu Oct 02 2008 00:16 < ybit> http://www.unicornscan.org/ 02:28 < ybit> pk, nooooo! 02:28 < ybit> ... 02:28 < ybit> oi faceface 02:29 < ybit> why are we not subjected to three faces currently? 02:53 < ybit> procto: what exactly is logarchy doing? 02:53 < ybit> sounds like they have a good idea for a future civ 02:53 < UtopiahGHML> ybit: want to apply to Blinkenshell? 02:53 < ybit> UtopiahGHML: sure 02:54 < ybit> if it takes awhile, i will have to do it tomorrow night or this weekend 02:54 < UtopiahGHML> nope the test=10min 02:54 < UtopiahGHML> the rest is getting vouched by 2 persons and that just hanging around in the channel helping 02:54 < UtopiahGHML> if you are social it's like 2 days max 02:54 < UtopiahGHML> then the following day the admin opens you account 02:55 < UtopiahGHML> so in the end if you are "dedicated" you could have it opened tomorrow :P 02:55 < UtopiahGHML> (they "work" on .se time) 02:55 < ybit> i might wait until this weekend when i am most active 02:58 < kanzure> Hi all. 02:58 < kanzure> ybit: skype please 02:59 < procto> ybit: it's just a general framework that can be applied 02:59 < procto> ybit: I'm involved with seasteading, and hoping to have a logarchy up on a seastead at some point during my life 02:59 < procto> thing about logarchy is that it's compatible with different electoral, political, and economic systems 03:04 < kanzure> fenn: nathan and michel on skype if you want to be bothered to have yet another chat protocol 04:05 < ybit> http://www.magcloud.com 04:07 < UtopiahGHML> I need a graph database library in PHP... 04:09 < ybit> UtopiahGHML: http://datamob.org/resources maybe? 04:10 < ybit> http://www.infochimps.org -- i think this belongs on the hplusroadmap wiki somewhere... 04:11 < ybit> or maybe it should just be bookmarked 04:15 < kanzure_> what is it? 04:16 < UtopiahGHML> ybit: graph as in mathematical graph, networks, not visually displaying data 04:17 < ybit> kanzure: infochimps -- "Free Redistributable Rich Data Sets" 04:17 < kanzure_> cool :) 04:17 < kanzure_> http://theinfo.org/ 04:18 < ybit> ah, i visited theinfo.org recently. me likey 04:19 < ybit> UtopiahGHML: http://www.hotscripts.com/Detailed/16749.html PHP+Graphviz tool 04:20 < ybit> a lot of php tools for graphiz: http://www.graphviz.org/Resources.php 05:24 < kanzure> ybit: soon you will have a fancy data set from me 05:24 < kanzure> and throwing it into graphviz will be simple 07:47 < willPow3r> kanzure, one login isn't enough? 07:50 < faceface> UtopiahGHML, graph database? What doing? 07:50 < faceface> ybit, I have enough face 08:18 < UtopiahGHML> faceface: relational database, no, object database, no, graph database specialized in network oriented datastructure, yes. 08:24 < faceface> yes 08:24 < faceface> what doing? 08:24 < faceface> I wanted to write a MySQL 'graph plugin', but I didn'y get round to it 08:25 < UtopiahGHML> I guess the best thing to do is too look at a real life example : 08:25 < faceface> I had a big 'graph database' hand out at one point... 08:25 < UtopiahGHML> http://neo4j.org/ 08:25 < faceface> kanzure___, are you still interested in this http://www.nature.com/nprot/journal/v2/n3/abs/nprot.2007.96.html? 08:25 < faceface> or was that last week? 08:26 < faceface> or should I say kanzure 08:26 < faceface> they do good stuff in Gronigen 08:27 < faceface> UtopiahGHML, OK, I know what a GraphDB is, my question is, what do you want one for? I am curious 08:28 < UtopiahGHML> oh 08:28 < faceface> I am interested in graph queries 08:28 < faceface> specifically traversing ontologies 08:29 < UtopiahGHML> to evolve from a wiki with a classical filesystem or classical DB to a way to handle data it holds in a consistent fashion 08:29 < UtopiahGHML> and be able to have a fully "querable" wiki 08:29 < UtopiahGHML> (mixing user modification and API modification basically) 08:29 < faceface> UtopiahGHML, its the future 08:29 < UtopiahGHML> thus facilitating automated agent suports 08:29 < faceface> UtopiahGHML, have you groked SMW yet? 08:29 < faceface> cool 08:30 < UtopiahGHML> nop, doesn't ring a bell, what is it? 08:30 < faceface> I really want to get my head into SMW, semantic media wiki 08:30 < faceface> but I haven't had time 08:30 < faceface> its semantic web for mediawiki 08:30 < faceface> they have a query interface that seems to mirror XSLT 08:30 < faceface> or XPah 08:31 < faceface> it was so strange thinking about hierarchical queries after so many years of thinking about relations 08:31 < faceface> UtopiahGHML, about 'api modifications', the guy behind DPL is going in that direction with his DPL + graph vis wiki 08:32 < UtopiahGHML> hmmm yep I checked SMW a while ago (>1 year) but it wasn't what I was looking for at the time (too complex for the end-user and too little applications ready, basically very low ROI) 08:32 < faceface> ROI? 08:32 < UtopiahGHML> return on investment 08:32 < faceface> UtopiahGHML, there is a SMW extension called Semantic Query or something 08:32 < UtopiahGHML> technical cost vs concrete features benefits 08:32 < faceface> OK 08:32 < faceface> this is friendly http://semeb.com/dpldemo/index.php?title=Dynamic_Page_List 08:32 < faceface> ROI ROI 08:33 < UtopiahGHML> having just 23h57 per day you have to think ROI :) 08:34 < faceface> It allows you to combine Wgraph with DPL to generate 'software' in the wiki 08:34 < faceface> http://semeb.com/dpldemo/index.php?title=Main_Page 08:34 < UtopiahGHML> hmmm problem is my current wiki is using pmWiki, do those solutions prodive way to "import" existing data? 08:34 < faceface> pmWiki? 08:34 < UtopiahGHML> very flexible wiki 08:35 < faceface> UtopiahGHML, there are libraries for wiki to wiki conversion, then you need to run MW to enable the DPL / Wgraph stuff 08:35 < UtopiahGHML> but that unfortunately doesn't provide a clear API and can't handle massive amount of data 08:35 < faceface> he is forging ahead 08:35 < faceface> UtopiahGHML, not in a 'live' system... I'm thinking of a one off migration 08:35 < faceface> http://semeb.com/dpldemo/index.php?title=Scatter_Demo_2 08:35 < faceface> its so cool 08:35 < UtopiahGHML> the good think with MW is... that I guess it has the largest active community 08:36 < faceface> yup, and WP proves its scaleable 08:37 < Utopiah> sorry, irssi crash... 08:38 < Utopiah> faceface: ideally Id use a structure like #OpenCog will use since Im into AI, the thing is (by luck?) my targeted architecture (hypergraph) is also what OpenCog decided to use 08:38 < faceface> what is the open cog? 08:38 < Utopiah> what I consider the more prosiming unifying AI project today 08:39 < Utopiah> (what some like to call "AGI") 08:39 < faceface> Utopiah, ... you want ... your wiki to be intelligent? 08:40 < Utopiah> not really :) 08:40 < Utopiah> what is the structure of a wiki? 08:41 < faceface> what is the way of tao? 08:41 < Utopiah> what is the structure of a brain? 08:41 < Utopiah> the hypergraph seem to be the most ready to use model for a convergence let's say 08:42 < Utopiah> so let's imagine one who would to enjoy what the Net can offer since it's (probably) the fastest evolvy ecosystem today 08:42 < Utopiah> one would want its data organized in a fashion that agent (including remote agents like API from other websites) to "play" with the data 08:43 < Utopiah> eventually seing his system itself as a potential useful other agents 08:43 < faceface> yes, thats the idea of SMW 08:43 < faceface> have you read the 'cyber infrastructure for Biology' paper? 08:44 < faceface> also my friend Vincent has worked on some neat stuff like this 08:44 < faceface> you can find his publications here: http://www.vincent-wolowski.net/ 08:44 < faceface> Building a Semantic Search Engine. Presentation, Department of Chemical System Engineering, Komiyama Laboratory, Tokyo University, Tokyo, Japan, February 3, 2004. [.pdf] 08:45 < Utopiah> 'cyber infrastructure for Biology' ? based on mimetic? 08:45 < faceface> what what? 08:45 < faceface> no 08:45 < faceface> not mimetic 08:46 < faceface> http://nrgwiki.nature.com/cyberinfrastructureforbiology/show/HomePage 08:47 < Utopiah> hmmm the more I look at those WM extensions the more Im considering a switch... what do you think is the core of the MW community? (to check what is available now, what is the spirit, etc... and betting on how it will evolve) 08:47 < faceface> Utopiah, uncertain 08:47 < faceface> see #mediawiki 08:48 < faceface> they are active... there are a few good devs... 08:48 < faceface> Byron is a controll freak... 08:48 < faceface> all revisions go through byron, and thats final 08:48 < faceface> (ime) 08:48 < fenn> control freak? wikipedia? you must be kidding! 08:48 < Utopiah> do you know if there is anything related to the use of GraphDB as the underlying strcture? 08:48 < faceface> heheh 08:48 < faceface> they are not too close to the wp community 08:48 < faceface> they are like... uh... users? 08:49 < wrldpc> wiki is all controlhawks. 08:49 < Utopiah> strange way to see an open community but maybe it's efficient... 08:49 < faceface> Utopiah, no 08:49 < faceface> just a pairs list or something 08:49 < faceface> Utopiah, I wanted to get svn commit access to one extension in the MW svn server - it was a no go 08:49 < faceface> just one extension! 08:50 < faceface> that is why many extensions are developed off site, and also just directly on mediawiki.org 08:50 < Utopiah> I see 08:50 < faceface> There are so many extensions because of an unwillingness to integrate into the core 08:50 < faceface> however... that said... there is a lot of exciting stuff going on in the extension community 08:50 < faceface> esp. bio. 08:51 < faceface> wrldpc, turns out that way for some reson often 08:51 < Utopiah> the last thing that amazed you there? 08:51 < faceface> wikipathways 08:51 < faceface> its a pahtway editor in the wiki 08:51 < wrldpc> does anyone here actually sub to nature? 08:51 < faceface> also (a bit boring) I am excited by the 'data integraton' efforts in MW 08:52 < faceface> wrldpc, http://network.nature.com/people/dan/profile 08:52 < wrldpc> I sent off a rather pointed message encouraging them to go "free." 08:52 < wrldpc> interesting 08:53 < faceface> Utopiah, my MW / bio projects are pretty amazing too ;-) 08:53 < faceface> http://pdbwiki.org/index.php/Main_Page 08:53 < faceface> http://biodatabase.org/index.php/Main_Page 08:54 < faceface> also you should see http://bio.cc/index.html/index.php/Main_Page 08:54 < faceface> wrldpc, write a 'letter to nature', get people to sign it 08:54 < wrldpc> good idea 08:55 < faceface> You just got to cram it all in to 200 words :-) 08:55 < faceface> well... I need to go do my day job... any tips on how to get by on less sleep? 08:57 < Utopiah> more sport, better nutrition but overall the trick is... 08:57 < Utopiah> PASSION! :D 08:58 < wrldpc> hey faceface have you heard of the project John Cumbers from Brown wants to do where people would swab their toilets and mouthes and so on and ... 08:58 < Utopiah> but ... A candle that burns twice as bright and twice as long 08:58 < wrldpc> Does anyone know about this? 08:58 < Utopiah> not sure it exsits, your choice though :) 08:58 < faceface> Utopiah, yeah... I get bored though ... I am a dysfunctional 08:58 < faceface> wrldpc, no 08:59 < faceface> wrldpc, what is it? 08:59 < faceface> 'eco-genomics'? 08:59 < wrldpc> bioinformatics project 08:59 < wrldpc> sorta 08:59 < faceface> like environmental sampling? 08:59 < wrldpc> they want to track where stuff is ... open source, yes envirosamp 08:59 < faceface> its the future :-) 08:59 < wrldpc> bingo 08:59 < wrldpc> have a good day! 08:59 < faceface> you too 08:59 < Utopiah> faceface: how can you be bored in such a time and place... :) 08:59 < wrldpc> thanks 08:59 < faceface> Utopiah, I am 'purpose disoriented' 09:00 < faceface> I don't really know what I want or why... I am conflicted. 09:00 < Utopiah> strange since you seem to have your own projects 09:00 < faceface> anyway... I 'feel' like I should go do my boring day job... Its like a pressure... 09:00 < faceface> I do them in my spare time... hence the need for less sleep 09:00 < faceface> nice talking to you Utopiah 09:01 < Utopiah> my pleasure 09:01 < Utopiah> have a nice day 09:03 < fenn> faceface: try doing your personal projects while at normal job 09:04 < Utopiah> fuck your normal job, move to what you really live for, find a way to monetize it. 09:04 < fenn> well, yeah, but that takes passion 09:06 < Utopiah> indeed 09:07 < Utopiah> but that's when your life really starts :) 09:16 < faceface> anyone married 09:16 < faceface> ? 09:21 < Utopiah> gosh no 09:22 < faceface> heheh 09:22 < faceface> I thought I was taking a job that supported my interests 09:22 < faceface> but it was also a compremize for me and my wife 09:23 < faceface> I think I'll have to become a 'group leader' just to get to work on what I want to! 09:23 < Utopiah> entrepreneur is the spirit 09:23 < Utopiah> and it's a long time investment 09:23 < faceface> OK, lets start a business 09:23 < Utopiah> the risk is not not to bet but not to know that you are betting anyway 09:24 < faceface> I really need someone to talk to about that.... 09:24 < Utopiah> opportunity cost basically 09:24 < faceface> I have a killer idea if we can get to prototype within 6 months 09:24 < Utopiah> well, Im a idea management pro 09:25 < faceface> cool... the problem with 'nextGen' sequencing is that its too good - too much data too quickly. We don't have enough disks. 09:25 < Utopiah> yep 09:25 < faceface> turn the problem on its head - lets encode our DNA data as DNA, then we can store vast quantities of data in a cupboard 09:25 < faceface> we can get massive data transfer rates by shipping DNA using UPS 09:26 < Utopiah> hmmm I met a woman on Berkeley working on a similar problematic but she wasn't going the same way 09:26 < faceface> the idea is to design a 'DNA encoding' that maximizes ease of reading 09:26 < Utopiah> yep I see 09:26 < faceface> exactly, we have a slight edge 09:26 < faceface> the two novel things that we bring together are 09:26 < Utopiah> problem is... cost of "DNA printing", isn't it very brittle and costly so far? (maybe not 2D structures thought, dunno) 09:27 < fenn> lol i have a direct DNA to DNA nano sequencer data storage machine - polII 09:27 < fenn> III 09:27 < faceface> 1) the DNA encoding - lots of check sums and handeling of repeat regions, 2) the 'DNA protectant' molecule that we use to store data at rtp 09:27 < faceface> fenn, its error prone ;-) 09:27 < faceface> Utopiah, exactly, we need to design a micro fluidic dna sequencing chamber 09:28 < faceface> microfluidics is getting very cheap, so its easy to design and print a 'chip' that will controll the flow of ATCG into a reaction chamber. 09:28 < fenn> cost of DNA printing is what all the "retarded polymerase" stuff is about 09:28 < faceface> really? 09:29 < fenn> sorta 09:29 < faceface> that stuff where I was like 'what are you guys going on about'? 09:29 < fenn> it's also for realtime in-vivo expression of arbitrary genes 09:29 < fenn> but whatever, it's vaporware 09:30 < faceface> sure 09:30 < fenn> <- bitter old man 09:30 < faceface> taq isn't expensive though 09:30 < fenn> is the patent up yet? 09:30 < faceface> I need a prototype no? 09:31 < fenn> oh i was just curious 09:31 < fenn> always wanted a vat of e-coli spewing out metric tons of taq polymerase 09:31 < faceface> but my feeling is that there is only a short window on this one 09:32 < fenn> i dont really see what sort of situation would require dna data storage? 09:32 < fenn> i mean what do you do with it 09:32 < faceface> fenn, when I sequence your genome for $10, then the genome of your gut, then the genome of your brain, then again at age 2 and again at age 6 and again and agin, 09:32 < faceface> then stick it into DNA 09:33 < faceface> its a 'permanant record' for re-reading 09:33 < faceface> like a tape backup 09:33 < fenn> why not use tapes? 09:33 < faceface> too expensive 09:33 < faceface> too many data 09:33 < faceface> too slow 09:33 < fenn> is there no compression algo? 09:34 < fenn> i mean you and me are 99% similar 09:34 < faceface> well... 09:34 * faceface sulks 09:34 < faceface> but its good to talk about 'alternatives' 09:34 < faceface> I mean a patent needs that right? 09:35 < faceface> fenn, also tissue expression could vary a lot, next gen gives you expression levels, splice variants etc. 09:36 < fenn> dont get me wrong, DNA is a fantastic data storage device 09:36 < fenn> but it's a pain in the ass to work with 09:36 < faceface> it seems to work 09:36 < faceface> ah... you know about any microfluidic considerations when working with DNA? 09:37 < faceface> there is a formidible group in cambridge that develops microfluidics for biotech 09:37 < fenn> um, how do you get past the typo problem? 09:37 < faceface> fenn, checksums 09:37 < fenn> probability of a typo increases exponentially with sequence length 09:37 < faceface> and redundancy... like read correction on any modern disk 09:38 < faceface> I am sure we can think of some 'optimal encodings' 09:38 < fenn> i dont know much about how microfluidics actually works (beyond a popular science level) 09:38 < faceface> also, we need read optimized ... i.e. taylored to certain hardware 09:38 < faceface> you trap a bubble of your aquious reagent in an oil flow. then you can manipulate the bubbles 09:39 < fenn> but how does this actually build up a sequence? 09:39 < faceface> i.e. read off bubble colour, sort, merge, store etc 09:39 < fenn> is it just the conventional modified NTP + cap molecule? 09:40 < faceface> you have a chamber with some fixed primers and taq, then you flow ATCG over the primer... actually I don't know! 09:40 < faceface> that is where my plan falls down... I'm an idiot! 09:40 < fenn> hrm 09:40 < fenn> "where the bits hit the road" 09:40 < faceface> somehow we need to keep taq in the 'reaction chamber' then we need to flow ntp at a time, then we need to get out the DNA and put in new primers. 09:41 < fenn> flow one ntp at a time won't work 09:41 < faceface> why? 09:41 < fenn> either too much diffusion or it's too slow 09:41 < faceface> I don't mean one molecule, just one type 09:41 < faceface> microfluidics is fast, you can process 100's of bubbles per second 09:42 < fenn> my idea was that you sensitize the taq with some frequency of laser and this only allows it to pick up a certain nucleotide 09:42 < faceface> each bubble needs to be one NTP.... and we need to only add one base per bubble... 09:42 < faceface> fenn, any ref? 09:42 < fenn> no 09:42 < faceface> any chem to spontainously 'prime' the end of the DNA for reaction? 09:43 < fenn> not needed, taq does that 09:44 < faceface> DNA-* + NTP -> DNA-NTP + * -> DNA-NTP-* +NTP -> DNA-NTP-NTP + * -> ... 09:44 < faceface> fenn, but I only want to add one base at a time 09:44 < faceface> taq is there ready to add as many NTP's as it can get its hands on right? 09:44 < faceface> or do you controll that with ATP? 09:44 < faceface> I'll need to read up to get more details 09:44 < fenn> well, the idea was to have another "clock" frequency 09:45 < fenn> so you have 3 lasers 09:45 < fenn> 2 spcify the nucleotide 09:45 < fenn> the third cements it in place 09:45 < faceface> I'll do some reading. 09:46 < faceface> I think there is scope for a 'strategic aliance' ;-) 09:46 < fenn> this was some idea i came up with years ago, i honestly have no idea if there's anything out there 09:49 < fenn> " An undefined problem has an infinite number of solutions. 09:49 < fenn> what a bunch of crap 09:50 < fenn> must have been a mathematician, not an engineer 09:51 < Utopiah> that's infinitely unuseful :) 11:00 < kanzure_> Utopiah: for what it's worth, I too want graphdb or graph-fs, and *not* in semantic mediawiki form. 11:01 < Utopiah> ideally I would find a Lisp wiki using GraphDB... 11:03 < Utopiah> (and super ideally be able to convert my existing wiki instance to it in 1 command ;) 11:05 < faceface> Similarly to concepts in electrical engineering, the objective in the Synthetic Biology is the development of standardized DNA building blocks, which can be easily combined and which allow the reconstruction of cells, e.g. bacteria into bioreactors. Scientists in the Synthetic Biology thereby aim at the development of bioreactors capable of producing far more complex compounds than currently possible using the conventional methods of classica 11:05 < faceface> l biotechnology 11:06 < faceface> http://sb4.biobricks.org/ 11:07 < kanzure_> faceface: you might be interested in knowing of my synthetic biology circuit creator project 11:07 < faceface> kanzure_, I just pasted for your benefit 11:07 < kanzure_> http://heybryan.org/~bbishop/docs/biobricks/ contains my work in progress. 11:07 < faceface> but I'll have a look 11:07 < kanzure_> faceface: surely you knew about biobricks beforehand? 11:07 < faceface> not that they had a conference 11:07 < kanzure_> :) 11:08 < faceface> http://www.marketwatch.com/news/story/geneart-ag-presents-its-work/story.aspx?guid={3E3BE543-8D0C-4BC1-973C-DD3B37908D76}&dist=hppr 11:08 < kanzure_> yeah, I'm missing that this year 11:08 < faceface> (when I pasted I didn't realize it was BioBricks) 12:35 < kanzure> http://www.washingtonpost.com/wp-dyn/content/article/2008/10/01/AR2008100101149.html 12:35 < kanzure> http://globalnation.inquirer.net/mindfeeds/mindfeeds/view/20081002-164190/In-Crisis-A-View-from-the-Trenches 12:35 < kanzure> http://jama.ama-assn.org/cgi/content/full/300/13/1580 13:16 < faceface> jama? 13:17 < faceface> google won't let me look at the wahington post 13:30 < nsh> wgat? 13:30 < faceface> good idea 13:30 < faceface> ? 13:37 < fenn> what's with all the wall-street mumbo jumbo? 13:52 < Utopiah> fenn: just bankers requiring explicit forced donations from non-bankers in order to boost their ROI despite the market fluctuations, nothing new really 13:54 < Utopiah> (alias Robin Hood^-1 alias classical world resources redistribution) 13:55 < fenn> i meant why was kanzure posting links to these pointless newspaper articles 13:57 < nsh> the contain encoded messages, clearly 14:08 < faceface> complexity? 14:37 * nsh was just being glib 14:38 < bkero> glubglubglub 17:06 < kanzure___> fenn: received those links from somebody pointing out the commonality of 'complexity' between the recent articles 17:07 < kanzure___> not sure it has much relevance of course :) 17:08 * kanzure___ just saved and submitted http://heybryan.org/~bbishop/docs/me302/2008-10-02_terminal_support_final.jpg 17:08 < kanzure___> 'part mating' is a joke. 17:08 < kanzure___> a bad joke. 17:10 < fenn> highly unenlightening, as any drafted diagram ought to be 17:15 < kanzure___> you already know I'm being prodded into following a workbook :) 20:36 < kanzure___> what's the longest you've gone writing code without testing it? 21:09 < kanzure___> bwaahahah. four hours of coding and only one syntax error. 22:39 < kanzure> http://heybryan.org/~bbishop/docs/repo/2008-10-02.pl 22:39 < kanzure> wtf 22:39 < kanzure> I don't remember writing the majority of that .. 23:13 < kanzure> "This goes to the heart of the infamous "Grounding Problem" in machine intelligence and to a pragmatic view of semantics. Simply put, the "meaning" of any referent corresponds with its observed effect within a particular context. No end-to-end grounding is ever ultimately needed nor ultimately possible." 23:13 < kanzure> "This strikes me as especially funny when it involves would-be AI creators imagining that a "relatively simple" computer program could encapsulate a process delivering "intelligence" while they remain blithely unaware and unconcerned about the essential contribution of the layers of software, microcode, electronic hardware, turtles all the way down... (within an environment of adaptation supporting such activity.)" 23:28 < kanzure> "Interesting that the first successful private commercial launch to orbit was achieved right at the peak of the end of capitalism." 23:57 < kanzure> 75359 23:57 < kanzure> :)