--- Log opened Sun Dec 12 00:00:08 2010
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04:12 < JayDugger> Good morning, everyone.
04:31 < shady_> gm :)
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05:48 < alystair> anyone here in Arizona?
05:48 < JayDugger> Not this week.
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06:59 < dbolser> 14:25 < delinquentme> dbolser, ummm when cells divide they snip a bit of the telomere off the end ... 
06:59 < dbolser> unavoidably, yes, because of the nature of the DNApol
07:00 < dbolser> when non circular DNA is replicated, it ends up a bit shorter
07:17 < dbolser> quite funny: http://noosphere.princeton.edu/
07:17 < dbolser> anyone bitten the morphogenesis bug?
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09:13 < kanzure> why does everything lead back to Tetrahedron Letters
09:14 < JayDugger> "Six Whys" sucks at work. Must we do it here?
09:15 < JayDugger> What led you to Tetrahedron Letters?
09:23 < bdesk> dbolser: the brain is not an organ which creates thoughts, it is an organ which captures thoughts from the global consciousness by sympathetic vibration
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09:42 < delinquentme> GOOD MORNING EVERBODAH!
09:44 < kanzure> JayDugger: freitas cites tetrahedron letters occassionally
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09:57 < kanzure> antikythera mechanism
09:57 < kanzure> http://www.youtube.com/watch?v=RLPVCJjTNgk
09:57 < kanzure> http://www.youtube.com/watch?v=L1CuR29OajI
09:57 < kanzure> more info http://www.youtube.com/watch?v=_PrlERqn2Qc
09:57 < alystair> seriously, human flight is one thing
09:58 < alystair> getting wifi/internet during a flight..  we live in a miraculous age
09:58 < kanzure> the second video is probably better
09:58 < bdesk> alystair: that sounds like the start of a louis ck standup
10:00 < alystair> bdesk: I guess we both don't like taking things forgranted?
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10:04 < kanzure> http://diyhpl.us/~bryan/irc/freitas_process.txt
10:04 < kanzure> this really seems like an awful procedure
10:04 < bdesk> http://www.youtube.com/watch?v=8r1CZTLk-Gk&t=2m
10:05 < kanzure> i'm surprised he hasn't figured out some sort of electrically-charged method of atom deposition or something
10:06 < kanzure> so that you don't need to do this sort of "two layer" deposition process (where you grow a crystal on top of the tooltip so that you can mechanically remove the crystal+tooltip leaving the tool bit behind..)
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10:10 < JayDugger> I'd complain too if I paid good money for in-flight Internet service that failed.
10:10 < JayDugger> Imaging the Antikythera Mechanism (Tom Malzbender, Polynomial Texture Maps, but no Lego)
10:10 < JayDugger> http://www.youtube.com/watch?v=rxNg-tXPPWc
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10:43 < delinquentme> WOOT! back @ it
11:11 < delinquentme> QUESTION... so with this action .. what do you guys think about making a list of microfluidic companies im gonna contact .. and say THIS IS WHAT IM DOING ... HERE ARE THE COMPANIES IM TALKING TO .. if you want to help and give me the best terms .. youll be my choice supplier
11:11 < delinquentme> its mildly coersive ...
11:11 < delinquentme> BUT
11:11 < delinquentme> ends justify the means
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11:12 < kanzure> delinquentme: try this list
11:12 < kanzure> http://fluidicmems.com/list-of-microfluidics-lab-on-a-chip-and-biomems-companies/
11:12 < delinquentme> yeah theres also the list from the "whos who in biogerontology companies"
11:13 < delinquentme> WHICH! btw .. ive worked out access to that database ... theres gotta be good ways to leverage with with what im doing
11:16 < kanzure> if you want reading material try http://bio.cc/Bioinformics/papers/microfluidics/
11:25 < delinquentme> kanzure, have you read through any of these? any of which you could recommend for being easy reads?
11:28 < kanzure> i've read through the vast majority
11:29 < kanzure> what do you want to read in particular?
11:29 < kanzure> any of the files with "Review -" in their name might be a nice introduction to whatever they are a review of..
11:29 < delinquentme> awesome.
11:29 < delinquentme> kanzure, actually let me take a step back here ... im still unsure if microfluidics is the way to go
11:30 < kanzure> anywho, i'm reading freitas' proposed method of diamondoid manufacturing
11:30 < kanzure> 1) Synthesize capped tooltip molecule
11:30 < kanzure> 2) Attach tooltip molecule to deposition surface w/ correct orientation
11:30 < kanzure> 3) Attach handle structure to tooltip molecule
11:30 < kanzure> 4) Separate finished tool from deposition surface 
11:30 < kanzure> in step 3 he does CVD to grow crystals around the tooltip molecule so that in step 4 he can mechanically remove the crystal+tooltip by force
11:30 < delinquentme> ^ thats nanotech is it not?
11:30 < kanzure> but why not just grow the crystal on the tooltip molecule in the first place while you are synthesizing it in step 1
11:30 < delinquentme> like holy christ .. nanotech is a whole other ballgame
11:31 < delinquentme> literally another completely viable way to go about working out the debilitations of aging
11:31 < kanzure> then you attach the tooltip+handle to an AFM cantilever beam, then move it to the correct location
11:32 < kanzure> maybe he's worried that if you use an AFM cantilever to press it against the surface that you won't only be using the dimer at the bottom of the tooltip as the surface intersection
11:33 < kanzure> aren't AFM tips supposed to be single atom diameters in some instances?
11:35 < delinquentme> kanzure, you've lost me
11:40 < kanzure> oh here's an AFM tip with a carbon nanotube (1.8nm diameter tip) http://alice.berkeley.edu/content/pubs/Lengthcontrolandsharpening.pdf
11:42 < delinquentme> kanzure, are you talking to someone that i have ignored or??
11:50 < bdesk> delinquentme: AFM = atomic force microscope; CVD = carbon vapor deposition
11:50 < delinquentme> yeah i just checked it out ... i like the MASSIVE case surrounding the microscope
11:51 < delinquentme> #deathlycool
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12:08 < kanzure> Quantum transport through atomic wires http://hub.hku.hk/bitstream/10722/42445/1/38947.pdf
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16:02 < joshcryer> Wow, "pantorouter": http://www.youtube.com/watch?v=8wZ1v4PIsYI and demo http://www.youtube.com/watch?v=PDPrFJazD3Q
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16:27 < kanzure> i wish there were more 3 to 5 letter words in mechanical engineering topics
16:27 < joshcryer> me too
16:27 < kanzure> hello joshcryer
16:27 < joshcryer> you have to go to 80 year old textbooks to find it
16:28 < kanzure> i've looked through those (on google books) and they don't use short words for anything
16:29 < kanzure> except maybe: gear, belt, pin, plug, bolt, nut, nail, tack, screw
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16:58 < bdesk> pants
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19:06 < delinquentme> HERRROOO!!! just saying i <3 all you guys!
19:10 < jrayhawk> d'awwww
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19:41  * delinquentme cheezin i know
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20:01 < QuantumG> saw some Mendels printing yesterday
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20:10 < kanzure> QuantumG: want your money back?
20:11 < QuantumG> didn't spend any
20:11 < QuantumG> and I guess that's why I think it's pretty neat
20:14 < QuantumG> I showed em the Gada Prize too.. they didn't seem interested.
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20:22 < kanzure> this one is sexy
20:22 < kanzure> Reengineering CCA-adding enzymes to function as (U,G)- or dCdCdA-adding enzymes or poly(C,A) and poly(U,G) polymerases
20:22 < kanzure> http://www.pnas.org/content/104/1/54.abstract
20:23 < kanzure> "We were able to transform the CCA-adding enzyme into a (U,G)-adding enzyme that incorporates UTP and GTP instead of CTP and ATP; we transformed the related Aquifex aeolicus CC- and A-adding enzymes into UU- and G-adding enzymes and Escherichia coli poly(A) polymerase into a poly(G) polymerase; and we transformed the B. stearothermophilus CCA-adding enzyme into a poly(C,A) polymerase by mutations in helix J that appear, based on the apoenzyme struct
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21:15 < kanzure> blah does anyone remember that paper where they biotinylated a polymerase to an AFM/SPM probe tip?
21:18 < QuantumG> nah, sorry
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21:48 < kanzure> ok what about anything that talks about the current through polymerase enzymes during dNTP incorporation
21:52 < kanzure> dbolser: you wouldn't happen to know a reference would you?
21:58 < joshcryer> speaking of mechanical engineering, which we weren't, but how might one take a bunch of low torque high rpm inputs and make them be high torque low rpm?
22:00 < kanzure> cog?
22:00 < kanzure> actually i retract my statement and proceed to bed
22:00 < kanzure> good night
22:01 < joshcryer> 'night
22:02 < joshcryer> I'm thinking a cam actually but I'm trying to figure out how to tie them together
22:04 < jrayhawk> http://www.youtube.com/watch?v=EAELukfr2oY you use the coolest gear ever invented
22:09 < joshcryer> jrayhawk, that is fucking perfect. Thanks.
22:11 < joshcryer> Also, brilliant, I wish I actually thought of that. -_-
22:14 < joshcryer> Stupid YouTube.
22:15 < joshcryer> Almost anything to do with magnets = perpetual motion / overunity garbage.
22:15 < joshcryer> :(
22:19 < QuantumG> heh, this Falcon 9 / Dragon module for Orbiter has some issues
22:20 < QuantumG> "press P to separate Dragon from the second stage" ok, presses P twice, two Dragons separate from the second stage :)
22:24 < jrayhawk> the magnetic gear also being able to act as a low-heat binary clutch and torque limiter is pretty fucking amazing, too
22:35 < joshcryer> QuantumG, yeah, can't even select it.
22:35 < joshcryer> QuantumG, unless you use the editor, etc.
22:42 < QuantumG> it's not an actual Dragon
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22:51 < joshcryer> Would it even qualify as an actual Falcon 9?
22:58 < QuantumG> dunno.. but the Dragon actually says "qualification unit" in the scenario editor
22:58 < QuantumG> and if you select it you get no manoeuvring fuel
22:59 < joshcryer> It's buggy, I couldn't figure out how to fly it to the moon. :(
22:59 < QuantumG> I flew the second stage there
23:00 < QuantumG> after refueling in leo
23:00 < joshcryer> How?
23:00 < joshcryer> Hehe
23:00 < joshcryer> Manually just flew around? I couldn't even find the moon.
23:01 < QuantumG> you either have to:  in orbit, align planes with the Moon
23:02 < QuantumG> or: on the ground, launch into 5.28 degrees
23:02 < QuantumG> either way, you get to orbit in 5.28 degrees inclination.. now refuel.
23:02 < QuantumG> then select Transfer
23:02 < QuantumG> TGT the Moon
23:02 < QuantumG> turn on HTO
23:03 < QuantumG> hold down DV+ until your DV gets to 3107m/s or so
23:04 < QuantumG> by now you should see an ellipse reaching out to the orbit of the Moon.. now you use EJ+ to move that ellipse around.. you might have to DV+ a little more now and then
23:04 < QuantumG> line up the grey middle line of the ellipse with the yellow dotted line (which will keep moving as you move)
23:05 < QuantumG> once that's done you just wait (use T to speed up time, R to slow back down) until the moving line is almost on the start line (DTe will get to about 180)
23:05 < QuantumG> now burn (number pad +)
23:06 < QuantumG> you'll probably have to burn as much past the start line as you burn before it
23:06 < QuantumG> the Dv will go down.. you want it to go to 0 but you can just eyeball the ellipse until it matches what you set.
23:06 < QuantumG> now you're on your way to the Moon... wait 3 days.
23:07 < QuantumG> when you get there you want to burn retrograde to circularize your orbit.
23:10 < joshcryer> Nice, thanks for the little tutorial.
23:11 < joshcryer> (I'll still get it wrong but I didn't know you could change targets, etc)
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--- Log closed Mon Dec 13 00:00:07 2010