--- Log opened Sat Jan 08 00:00:06 2011
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01:54 < Utopiah> (for those against orgmode http://code.google.com/p/vimwiki/ )
02:00 < Lukas__> Good morning
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07:18 < kanzure> "DENDRITES ARE SPROUTING OUT OF MY SKULL!!" http://groups.google.com/group/rec.drugs.smart/browse_thread/thread/62bbf6c304b20cd4#
07:20 < jennicide> i have that problem too
07:21 < kanzure> it's very common
07:22 < jennicide> there is a guy on one of my networks claiming that he is a cyborg
07:22 < jennicide> i almost directed him here, but thought better of it
07:23 < kanzure> does he work on projects or is he just spammy?
07:23 < jennicide> or a third option
07:23 < jennicide> mentally unstable
07:24 < jennicide> 08:16 Imk0tter • jaytea, there's a good portion of the world, that we refer to as being human
07:24 < jennicide> 08:16 Imk0tter • jaytea, and they really arent.. they're androids
07:25 < jennicide> is embedding rare earth magnets into your finger tips still the new hot thing or is that passe by now?
07:31 < kanzure> it's not new at all..
07:32 < kanzure> also, hi.
07:35 < jennicide> right, so passe
07:38 < uniqanomaly> cyborg, hah
07:39 < uniqanomaly> guy needs help
07:39 < Lukas__> heh
07:40 < Lukas__> sounds like
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07:51 < kanzure> http://harkopen.com/news/arduino-documentary-2010-english-hd
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08:11 < kanzure> hm designfiles.org is now redirecting to graphsynth.com
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08:16 < gnusha> d720328 a long-overdue list of blab equipment useful for do-it-yourself biology
08:17 < kanzure> blab equipment?
08:17 < kanzure> GNUSHA!!!
08:18 < Lukas__> Hello gnusha
08:19 < gnusha> add60ea a long-overdue list of lab equipment useful for do-it-yourself biology
08:19 < kanzure> that's better.
08:21 < Lukas__> What sort of lab equipment?
08:21 < kanzure> check out revision add60ea to skdb.git
08:22 < kanzure> http://diyhpl.us/cgit/skdb/commit/?id=add60eab8a6f3e128476b3ebcdf388e29ede8ae7
08:22 < kanzure> http://diyhpl.us/cgit/skdb/plain/doc/BOMs/diybio-equipment.yaml
08:23 < kanzure> 'glassware' is cheating
08:25 < Lukas__> wtf?  How do you sell a fume hood?
08:25 < kanzure> sell?
08:25 < Lukas__> grr
08:25 < Lukas__> aim conversation
08:25 < kanzure> you could put a listing up on ebay
08:25 < Lukas__> and this
08:25 < Lukas__> at the same time
08:25 < Lukas__> ....
08:25 < kanzure> craigslist too
08:25 < Lukas__> human brains suck
08:28 < Lukas__> heh, didn't know that was actually possible
08:29 < kanzure> you might find other things of interest here:
08:29 < kanzure> http://diyhpl.us/cgit/skdb/tree/doc/BOMs/
08:38 < AlonzoTG> om?\
08:40 < kanzure> AlonzoTG: do you work with milling machines?
08:40 < AlonzoTG> I had the pleasure of repairing a 20 year old milling machine once,
08:40 < AlonzoTG> but I don't actually use them...
08:51 < AlonzoTG> Netgear is now on my shitlist.
08:51 < AlonzoTG> =|
08:52 < AlonzoTG> 1. my netgear router will loose the ability to serve wireless connections after a few months due to network latency...
08:52 < AlonzoTG> 2. When I get a bad sector report on my Ready NAS, I try to go to netgear's site to find out what drives I should put in it, the site is down!!!
08:53 < AlonzoTG> A network services company that can't keep their own network running?? SHEESH!!!
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09:31 < gnusha> 56725a9 more diybio-related equipment and greatly improved file organization
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09:33 < kanzure> hi fitzsim
09:33 < fitzsim> hi kanzure
09:33  * kanzure was just editing http://diyhpl.us/cgit/skdb/plain/doc/BOMs/diybio-equipment.yaml
09:34 < kanzure> oh you might be a good candidate to review the draft package specification i got fenn to start on yesterday
09:34 < kanzure> http://diyhpl.us/cgit/skdb/plain/doc/package_spec.yaml
09:34 < kanzure> esp. from a ne-1, nanotech, or molecular machine perspective
09:38 < kanzure> fenn: in package_spec.yaml under optional->updated, i think you mean pre-commit hook? otherwise you'll be generating spurious commits right?
09:39 < Lukas__> http://www.tasktop.com/videos/mylyn/webcast-mylyn-3.0.html
09:40 < Lukas__> Courtesy of Travisar
09:43 < kanzure> what is it? the link isn't very descriptive
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09:49 < kanzure> hi gloop. today's backlog: http://gnusha.org/logs/2011-01-08.log
09:49 < gloop> thanks
09:50 < gloop> Kanzure, do you read Glyn Moody?
09:50 < gloop> https://twitter.com/#!/glynmoody
09:50 < gloop> interesting source
09:51 < gloop> i'm currently reading about Quora...
09:53 < kanzure> yeah i twitterfollow glyn
09:53 < kanzure> http://poeticeconomics.blogspot.com/2011/01/plos-one-now-worlds-largest-journal.html
09:53 < kanzure> http://poeticeconomics.blogspot.com/2006/08/dramatic-growth-of-open-access-series.html
09:56 < kanzure> gloop: i used quora to see who in my social network is a super-early adopter
09:56 < kanzure> based on notifications of when they start to follow me
09:56 < kanzure> results: http://diyhpl.us/~bryan/irc/followers-quora-ordered
09:56 < gloop> ok yeah i read in sfgate
09:57 < kanzure> huh?
09:57 < gloop> just the article
09:57 < gloop> i was just referring to the practice
09:58 < kanzure> ah, different. the article in sfgate was about http://diyhpl.us/cgit/meetlog/plain/meetlog.txt
09:58 < kanzure> i'm just mentioning the quora thing because it shows adoption rates which might be interesting to someone.
09:59 < gloop> cool, yeah i was curious about that. i'm a bit of an early adopter when i see an interesting use
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10:09 < gloop> fume hoods would benefit from rooms with negative pressure
10:09 < gloop> if i'm not mistaken
10:09 < gloop> sealed doors would be needed
10:10 < gloop> not that sealed, thought
10:10 < gloop> (reading back in the irc logs of today)
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11:29 < kanzure> "The printed future of Christmas dinner" http://www.bbc.co.uk/news/technology-12069495
11:29 < kanzure> hrm so hod lipson wants everyone to call them 'fabapps'?
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11:30 < kanzure> hi wrldpc2
11:31 < wrldpc2> greetings from japan
11:31 < wrldpc2> bryan have you located a torrent or drop for transcendent man anywhere?  I'm kind of shocked it hasn't been leaked yet
11:31 < kanzure> no i haven't found one yet
11:32 < kanzure> my best guess why is because (1) nobody working for ray knows how to copy it effectively or (2) nobody likes it enough
11:32 < uniqanomaly> "It's outrageous that it has taken two years to release this film. Somebody must see the irony in this, in that this film is about the exponential speed with which technology advances? "
11:32 < kanzure> wrldpc2: on a related note you might like my new year's project: http://diyhpl.us:9000/random
11:33 < uniqanomaly> oh irony
11:33 < wrldpc2> lol
11:33 < wrldpc2> kanz: tight
11:33 < wrldpc2> oh cool
11:33 < wrldpc2> i'll definitely help promote this
11:34 < kanzure> it needs more bug fixes first
11:34 < kanzure> so right now it's just friends
11:35 < kanzure> suggestions/ideas/bug reports appreciated
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11:55 < wrldpc2> http://www.inventables.com/
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13:05 < kanzure> The Application Of Business Models To Medical Research: Interviews With Two Founders Of Directed-Philanthropy Foundations http://content.healthaffairs.org/content/26/4/1181.full
13:05 < kanzure> or a transcript from open science summit 2010: http://gnusha.org/transcripts/open-science-summit-2010/scott-johnson-myelin-repair-foundation.html
13:05 < kanzure> oh hm i should use this link for that last one:
13:05 < kanzure> http://diyhpl.us/diyhpluswiki/transcripts/open-science-summit-2010/scott-johnson-myelin-repair-foundation/
13:06 < kanzure> http://www.myelinrepair.org/research_model/research_process.shtml
13:06 < kanzure> sounds great but i'm a little concerned that their idea of "self-sustaining" is feeding their org off of revenues from patent licensing
13:16 < kanzure> heh..
13:16 < kanzure> http://git.spi-inc.org/gitweb/?p=website.git;a=blob_plain;f=meetings/minutes/1998/1998-09-24.mdwn;hb=7cdae9fa30bb1edbbf42236be3099d6eec106227
13:16 < kanzure> "* Consolidate, clarify, and document SPI's relationship with the "Open Source" project and Eric Raymond."
13:16 < kanzure> hmm
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13:28 < kanzure> didn't know patri runs a blog: http://patrissimo.livejournal.com/
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14:38 < gnusha> 8739717 various updates to package_spec.yaml (listed below)
14:38 < kanzure> jrayhawk: is there a way yet to move my http docs root for ikiwiki inside a repository to somewhere other than /?
14:38 < kanzure> i.e. for http://gnusha.org/skdb/
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14:47 < gnusha> 178d7c5 we also need a short description for each project
14:47 < kanzure> though we could just force the first line of 'description' to be at most 140 characters, and just use that for concise descriptions of projects
14:54 < kanzure> so with only 'software' dependencies being mandatory, there's essentially no reason to not use python eggs
14:55 < kanzure> and pip
14:58 < Lukas__> Hello
14:59 < kanzure> hi
14:59 < Lukas__> What insane project have you taken up today?
15:04 < kanzure> just nitpicking fenn's hardware package format specification http://diyhpl.us/cgit/skdb/plain/doc/package_spec.yaml
15:04 < kanzure> fenn: speaking of which, tim's request was actually for skdb-get.py or something like it to start working again
15:04 < kanzure> originally packages were being stored at http://designfiles.org/packages/ but since that's not an option, something on gnusha.org would make sense to me
15:05 < kanzure> formalizing what the client should do or something would be worthwhile
15:05 < kanzure> my first go at the client from 2008 or 2009 was basically a piece of junk
15:08 < kanzure> putting packages in /usr/share/skdb/ will probably not fly for most users, it should probably be in $HOME or otherwise configured by the user when they install the client
15:09 < kanzure> (put the configuration detail in ~/.skdbconf or whatever)
15:09 < kanzure> the reason i say that it won't fly is because people don't want these things hidden as far as i can tell
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16:49 < jrayhawk> Yeah, you can change srcdir in a later version of piny. I can probably upgrade you later today.
16:50 < kanzure> hooray
16:53 < Lukas__> quick question
16:54 < Lukas__> if you've got a artificial human tissue in the lab, could you stimulate some sort of immune response by introducing a virus?
16:55 < kanzure> what tissue?
16:56 < kanzure> you need blood
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17:00 < Lukas__> ...
17:00 < Lukas__> ....
17:00 < Lukas__> I am retarded
17:00 < Lukas__> never mind
17:00 < kanzure> *shrug* immune system experiments are still something that go on
17:00 < kanzure> derya unutmaz is a transhumanist in the community who is also a professor of immunology somewhere in new york
17:00 < kanzure> oh wait. microbiology? that doesn't sound right
17:00 < kanzure> http://www.med.nyu.edu/microbiology/faculty/unutmaz/
17:01 < kanzure> "Dr. Unutmaz' research focuses on the molecular machinery of T cell activation, differentiation, survival and its explotation by HIV."
17:01 < kanzure> description of his research: http://www.med.nyu.edu/microbiology/faculty/unutmaz/unutmaz_res.html
17:01 < Lukas__> O_O
17:02 < Lukas__> thanks
17:03 < kanzure> he has a few patents related to some cure for HIV
17:03 < kanzure> i think it's held up in FDA limbo
17:03 < Lukas__> The
17:04 < Lukas__> freakin' FDA
17:04 < kanzure> fascist death administration
17:04 < kanzure> fucking death administration
17:04 < kanzure> federal death administration
17:04 < kanzure> etc.
17:06 < Lukas__> The were necessary back in the day, but now it's really, really bloated
17:06 < Lukas__> anyway
17:06 < kanzure> i do think due diligence on drugs is a good idea, though not for people who are at the end of the road
17:07 < Lukas__> I wanted to test gene therapy vectors on tissue samples to see if there was a) an immune response and if b) the protein was expressed (and the emergent properties)  - looks like I'll have to re-plan
17:08 < kanzure> why not work on the mouse model?
17:08 < kanzure> it's been extensively tested in genetic engineering
17:10 < Lukas__> My main worry is protein-protein interaction that may cause shit to go wrong - we already have clever ways of getting past the immune system, now can we make sure a protein won't do something it isn't supposed to do
17:11 < Lukas__> mice are excellent models
17:11 < Lukas__> but a handful of chemicals can makes things go terribly wrong
17:11 < Lukas__> so I wanted something as close to home as possible
17:19 < AlonzoTG> Retrovirus?
17:19 < AlonzoTG> I don't think those will ever work.
17:19 < AlonzoTG> The procedure that will work is to extract a cell, sequence the chromasome you want,
17:20 < AlonzoTG> edit it in vi (urk, don't ever use vi for anything!), synthesize the new chormasome, re-build the cell, culture it, and then re-introduce it to the organism.
17:20 < kanzure> what the hell is a chromasome
17:20 < kanzure> Lukas__: you should look into lentiviruses
17:20 < AlonzoTG> dunno; can't spell.
17:20 < AlonzoTG> U have 48 of them though.
17:21 < Lukas__> AlonzoTG, I had an idea about that
17:21 < Lukas__> using stem cells to create new cell lines
17:21 < Lukas__> but the issue is still the same
17:21 < Lukas__> the body will reject it
17:21 < kanzure> not always
17:21 < Lukas__> ...
17:21 < Lukas__> what now?
17:21 < Lukas__> what do you mean?
17:21 < AlonzoTG> Really? It shouldn't, the genetics would be 99% compatible.
17:22 < Lukas__> 1% is the problem
17:22 < Lukas__> whatever new protein it expresses will be tagged
17:22 < Lukas__> and destroyed
17:22 < AlonzoTG> How can an immune system be THAT sensitive?
17:22 < AlonzoTG> There have to be protene structures that it will permit.
17:23 < kanzure> also, you're talking about surface proteins
17:24 < AlonzoTG> Yeah, that could be a problem. =(
17:24 < kanzure> proteins inside the cell are not going to be finding their way into an antibody
17:25 < Lukas__> The immune system is a pain in the ass, and <kanzure> I still trying to figure out where the proteins will be with what I want to do
17:25 < Lukas__> but good point
17:25 < kanzure> Lukas__: you should read an article from the journal called "annual reviews" about genetic engineering of mice
17:25 < kanzure> i'm sure they have lots of reviews on genetic engineering by now
17:25 < Lukas__> alright, thanks
17:29 < Lukas__> wait a minute
17:29 < Lukas__> what happens when the cell dies?
17:41 < Lukas__> Wait, no, it doesn't undergo lysis
17:41 < Lukas__> which means this should work
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18:08 < Lukas__> I am checking out for the night
18:08 < kanzure> good night
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18:09 < kanzure> bugs everywhere just hit 1.0.0 a few minutes ago http://gitorious.org/be
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19:21 < kanzure> baidu is crawling hplusvideo
19:31 < kanzure> craig venter at space manufacturing 14 http://diyhpl.us:9000/s/craig-venter-synthetic-genomics
19:31 < kanzure> superkuh: ustream and others work now
19:32 < superkuh> Cool, thanks.
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20:08 < kanzure> silly unicode errors
20:10 < kanzure> space manufacturing 14 is up
20:10 < kanzure> open science summit 2010 is up
20:10 < kanzure> http://diyhpl.us:9000/s/session-4-1-robotics-and-space-manufacturing-mitchell-weiss
20:10 < kanzure> http://diyhpl.us:9000/s/session-4-2-robotics-and-space-manufacturing-greg-baiden
20:10 < kanzure> http://diyhpl.us:9000/s/prof-john-lewis-asia-s-road-to-the-moon
20:10 < kanzure> http://diyhpl.us:9000/s/prof-john-lewis-asia-s-road-to-the-moon-part-2
20:11 < kanzure> http://diyhpl.us:9000/s/session-5-1-engineering-materials-from-non-terrestrial-resources
20:11 < kanzure> http://diyhpl.us:9000/s/session-5-2-in-situ-production-of-construction-materials
20:11 < kanzure> http://diyhpl.us:9000/s/session-7-international-legal-and-economic-considerations
20:11 < kanzure> http://diyhpl.us:9000/s/session-7-international-legal-and-economic-considerations-ccdc8
20:11 < kanzure> now for open science summit 2010 highlights:
20:11 < kanzure> http://diyhpl.us:9000/s/the-role-of-universities-in-the-knowledge-economy
20:11 < kanzure> http://diyhpl.us:9000/s/alan-bennett-and-keith-bergelt-patent-pools
20:11 < kanzure> http://diyhpl.us:9000/s/bunin-hessel-izant-open-source-drug-discovery
20:12 < kanzure> http://diyhpl.us:9000/s/baber-benson-johnson-cure-entrepreneurs
20:12 < kanzure> http://diyhpl.us:9000/s/alternative-funding-mechanisms-for-science-r-d
20:12 < kanzure> http://diyhpl.us:9000/s/safety-and-security-concerns-open-source-biodefense
20:12 < kanzure> http://diyhpl.us:9000/s/microfinance-crowd-funding-for-science
20:12 < kanzure> http://diyhpl.us:9000/s/epistemology-2-0-the-future-of-online-science
20:12 < kanzure> http://diyhpl.us:9000/s/introduction-to-open-access-and-latest-developments
20:12 < kanzure> http://diyhpl.us:9000/s/gene-patents-moving-beyond-the-myriad-fallout
20:12 < kanzure> http://diyhpl.us:9000/s/human-genome-project-and-synthetic-biology
20:12 < kanzure> http://diyhpl.us:9000/s/citizen-science-in-biology
20:12 < kanzure> http://diyhpl.us:9000/s/mike-gretes-neglected-disease-r-d
20:12 < kanzure> http://diyhpl.us:9000/s/josh-perfetto-openpcr
20:12 < kanzure> http://diyhpl.us:9000/s/james-peyer-otyp
20:12 < kanzure> http://diyhpl.us:9000/s/todd-kuiken-responsible-science-for-diy-biologists
20:13 < kanzure> that should be enough for now :)
20:47 < kanzure> singularity summit videos
20:47 < kanzure> http://diyhpl.us:9000/s/anders-sandberg-at-singularity-summit-2009-technical-roadmap-for-whole-brain-emulation
20:47 < kanzure> http://diyhpl.us:9000/s/randal-koene-at-singularity-summit-2009-the-time-is-now-as-a-species-and-as-individuals-we-need-whole-brain-emulation
20:47 < kanzure> http://diyhpl.us:9000/s/ed-boyden-at-singularity-summit-2009-synthetic-neurobiology-optically-engineering-the-brain-to-augment-its-function
20:48 < kanzure> http://diyhpl.us:9000/s/william-dickens-at-singularity-summit-2009-cognitive-ability-past-and-future-enhancements-and-implications
20:48 < kanzure> http://diyhpl.us:9000/s/ray-kurzweil-at-singularity-summit-2009-the-ubiquity-and-predictability-of-the-exponential-growth-of-information-technology
20:48 < kanzure> http://diyhpl.us:9000/s/bela-nagy-at-singularity-summit-2009-more-than-moore-comparing-forecasts-of-technological-progress
20:48 < kanzure> "more than moore.. you could say.. max more?" ouch
20:48 < kanzure> http://diyhpl.us:9000/s/gregory-benford-at-singularity-summit-2009-artificial-biological-selection-for-longevity
20:48 < kanzure> http://diyhpl.us:9000/s/gary-marcus-at-singularity-summit-2009-the-fallibility-and-improvability-of-the-human-mind
20:48 < kanzure> http://diyhpl.us:9000/s/peter-thiel-at-singularity-summit-2009-macroeconomics-and-singularity
20:48 < kanzure> http://diyhpl.us:9000/s/aubrey-de-grey-at-singularity-summit-2009-the-singularity-and-the-methuselarity-similarities-and-differences
20:49 < kanzure> http://diyhpl.us:9000/s/anna-salamon-s-2nd-talk-at-singularity-summit-how-much-it-matters-to-know-what-matters-a-back-of-the-envelope-calculation
20:49 < kanzure> http://diyhpl.us:9000/s/venture-capitalist-panel-at-singularity-summit-2009
20:49 < kanzure> http://diyhpl.us:9000/s/sejnowski-bray-debate-will-we-soon-realistically-emulate-biological-systems-
20:49 < kanzure> http://diyhpl.us:9000/s/gregory-stock-evolution-of-post-human-intelligence
20:49 < kanzure> http://diyhpl.us:9000/s/dennis-bray-what-cells-can-do-that-robots-can-t
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--- Log closed Sun Jan 09 00:00:04 2011