--- Log opened Sun May 13 00:00:09 2012
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07:32 < eudoxia> so the CI site was redesigned
07:33 < eudoxia> it looks a lot less late nineties now
07:41 < ENKI-][> is that supposed to be a good thing?
07:41 < eudoxia> I suppose
07:42 < ENKI-][> a site that looks like it was made in 1997 isn't wasteful like a site that looks like it was made in 2007 is.
07:45 < eudoxia> why wasteful?
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09:26 <@kanzure> day 7 of gmail backup
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10:27 < klafka1> gmail backup?
10:34 <@kanzure> klafka1: just backing up my email with offlineimap
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11:30 < klafka1> perfect berry rockstar is the best rockstar
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11:54 < klafka1> argh does someone have familiarity with matplotlib ? i think i'm doing something dumb
11:56 <@kanzure> i've used it in the past, but not recently
11:56 <@kanzure> what's up?
11:57 < klafka1> either it is acting funky or my MCMC sampler is acting funky
11:57 < klafka1> not sure
11:57 < klafka1> i think i'm just going to implement this for discrete distributions and test it that way
11:57 < klafka1> sooo much easier to test MCMC with discrete distributions
11:58 < klafka1> also i'm not sure if this i correct but holy crap creating a hist from 10,000 data points is taking up 2gb of memory
11:59 < klafka1> that's insane
11:59 <@kanzure> hist = histogram?
12:07 < klafka1> yeah
12:07 < klafka1> something was weird there
12:07 < klafka1> it was going at 5gb when i killed it
12:10 <@kanzure> well, pastebin what you've got and i'll stare at it
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12:20 <@kanzure> i am disappointed by the lack of information on the intertubes about properly re-slinking a slinky
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13:12 < chevbird> happy mothers day
13:13 < ThomasEgi> kanzure, a histoframm from 10k datapoints should fit into 32k float values.
13:14 <@kanzure> ThomasEgi: for sure
13:14 < ThomasEgi> at leas. if you fourier transform with 16k input
13:14 < ThomasEgi> so how comes it takes so much memory?
13:14 < ThomasEgi> oh.. it appears i meant klafka1 instead of you
13:14 < ThomasEgi> silly autocomplete
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13:32 < klafka1> thomas yeah something is weird with it
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15:41 < Mariu> later everyone
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17:44  * n_bentha is going ape-shit
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17:51 < n_bentha> that little bastard
17:51 < n_bentha> he swore up and down that bglii had a cut site and that he could use bamhi instead of mfei
17:51 < n_bentha> i'll kill him!
17:58 < n_bentha> (there's no cut site for bglii for that fragment)
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18:28 <@kanzure> n_bentha: awesome
18:29 < n_bentha> :(
18:31 < yashgaroth> well at least it's presumably free labor
18:33 < n_bentha> ...
18:34 < n_bentha> yea but still. such a waste of time and money eventhough it's 'free'
18:34 <@kanzure> "For e[Cvery one mistake you make, we will add one additional year of grad school"
18:35 < n_bentha> hehe
18:36 < yashgaroth> I'm starting to reconsider grad school at this point
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18:38 <@kanzure> yashgaroth: did you get rejected
18:38 < yashgaroth> no response, which is seemingly so
18:38 < yashgaroth> lilly has another purification job opening soon, according to a director
18:39 < yashgaroth> but it's all either "oh this is a cloning job and you don't have a lot of professional time with that even though it's shit-easy"
18:39 <@kanzure> yashgaroth: you could also identify an opportunity and do a company,
18:39 < yashgaroth> or "ah you have purification experience, can you do [biochemical engineering]"
18:39 < yashgaroth> one does not simply do a company
18:40 < yashgaroth> all of the legal and profitable stuff is patented
18:40 < n_bentha> yashgaroth: i thought u were working?
18:40 < yashgaroth> was until late march, 2/3 of company got laid off :/
18:40 <@kanzure> n_bentha: his employer collapsed
18:40 < n_bentha> 0_o
18:41 < n_bentha> like as in fell over?
18:41 < n_bentha> or the company tanked?
18:41 < yashgaroth> the board decided not to continue funding due to lack of progress
18:41 < yashgaroth> it was supposed to be an alternative scaffold to antibodies, but "antibodies are doing a lot of new stuff these days so fuck it you're fired" basically
18:42 < yashgaroth> half-life, solubility and expression were all far lower than antibodies, so it was mostly to get around IP stuff
18:44 < yashgaroth> not that I'm bitter about the platform, but
18:44 <@kanzure> yashgaroth: so what's your plan ?
18:44 < yashgaroth> keep applying to the few jobs open here, maybe move to SF
18:47 < n_bentha> ah ok. hope you find something soon
18:47 < yashgaroth> I haven't been looking a whole lot, and diablo 3 coming out on tuesday shan't help matters I fear
18:53 < chevbird> where's here?
18:53 < yashgaroth> san diego
18:54 <@kanzure> chevbird: san diego
18:54 <@kanzure> damn you irc lag
18:54 < yashgaroth> mwahaha
18:55 <@kanzure> yashgaroth: you went from "independent consultant" to "research associate"? sounds like a downgrade
18:55 < chevbird> boston's pretty exciting biotech-wise lately if youre interested in leaving
18:56 < yashgaroth> nah that's their default position name for 'contractor'
18:56 < yashgaroth> nah I'm staying west coast
18:56 <@kanzure> yashgaroth: contractor sounds better than 'associate' but whoknows
18:56 < yashgaroth> it ain't, it's just another term for temp
18:56 <@kanzure> well definitely never write 'temp' on your resume
18:57 < yashgaroth> but yeah their standard was to hire all scientists on like that for the first 1-2 years
18:57 < chevbird> yikes
18:58 < chevbird> sounds like a runaround
18:58 < yashgaroth> it's so if you're shit they can fire you without dealing with those pesky employment laws
18:58 <@kanzure> one minor criticism about your resume.. you might want to consider a one-line statement or description for what your ideal role is
18:58 < yashgaroth> yeah I've been slyly tailoring it to whatever the job posting says
18:59 <@kanzure> i know "lab technician" doesn't sound ideal, but i can't think of a better description of what you did
18:59 < yashgaroth> research associate is the default for someone with a bachelor's, unless the company calls everyone scientists
18:59 < yashgaroth> though the terms are interchangeable
18:59 < chevbird> i lump associate scientist in there too
19:00 <@kanzure> ParahSailin has been following some bioinformatics leads, but it sounds like you would be happer with tissue and molecular work
19:00 <@kanzure> *happier
19:00 < ParahSailin> im employed :)
19:00  * yashgaroth shakes fist
19:00 <@kanzure> you took the houston job?
19:00 < ParahSailin> i switched from wetlab to in silico
19:00 < ParahSailin> yes
19:01 < yashgaroth> how much programming knowledge do/did you need?
19:01 < ParahSailin> wet lab is so cartelized it's ridiculous to want to get in there
19:01 < yashgaroth> blergh yeah
19:01 <@kanzure> yashgaroth: you shouldn't worry about programming knowledge; if you want to work on it, let me know and i can help you out
19:01 < chevbird> cartelized meaning?
19:01 < ParahSailin> i had no credentials, only the knowledge of data structures and general math skills that i brought to interview
19:02 < yashgaroth> hey sure as long as it's work
19:02 < ParahSailin> cartelized as in the instruments and equipment and all the reagents cost so much because of patents
19:02 <@kanzure> yashgaroth: i could probably get you to the point of getting a comfortable SF/SV programming job (but getting a bioinformatis gig i'm not so sure about; i'm sure it's possible, but i'm not presently optimized for that)
19:02 < ParahSailin> that big corps are the only game in town
19:02 < ParahSailin> or guys that have enough vc to buy those
19:02 < yashgaroth> well if it's not bio-related I don't know what I'd be doing there
19:02 < ParahSailin> and they are going to restrict access to that as much as they can
19:03 <@kanzure> yashgaroth: the way i suggest people do it is to make a demo product- usually a web app or mobile app- with a few weeks of your time, then parrot that around on your resume to land a junior programming gig
19:03 <@kanzure> yashgaroth: right..
19:03 < ParahSailin> my bioinformatics job is scripting next gen sequencing data parsing
19:03 < chevbird> ParahSailin: most are
19:03 <@kanzure> ParahSailin: also.. for lab work, i thikn there's an endless supply of cheap labor.. scienceeexchange isn't helping that, because there's tons of poor labs that would love to take on low-cost labor/work
19:03 <@kanzure> *think
19:04 < ParahSailin> the only difference between the PI/CTO in wet lab and the monkey at the bench is that the PI managed to convince someone with money to let him use that equipment
19:04 < ParahSailin> typically thats done through credentials or dicksucking
19:05 < ParahSailin> thats a killer barrier to entry, not worth attempting to assault in this day of permanent recession
19:06 < ParahSailin> thats why i sought out anything computer
19:07 < ParahSailin> because a terminal and a desk is negligible capital cost to risk
19:07 < yashgaroth> it's not like I mind benchwork, but after 12 hours of doing ELISAs, any amount of computer work seems blissful
19:08 < chevbird> if you guys are interested in the critique-the-resume game i'd love some input on mine doiop.com/chevrette
19:08 <@kanzure> chevbird: sure thing
19:09 <@kanzure> chevbird: ah shit, another biologist :)
19:09 <@kanzure> what brings you here?
19:09 < ParahSailin> i imagine my employer is not too unique
19:09 < chevbird> kanzure: i dont really know
19:09 <@kanzure> chevbird: just wondering how you know about ##hplusroadmap
19:09 < ParahSailin> any nextgen sequencing company is gonna need guys who can script basic parsing and assembly tasks and code some larger research projects
19:10 <@kanzure> chevbird: what sort of emulsions and automation have you done work on?
19:10 < chevbird> emulsion wise, basically illumina LC and specialty illumina LC (jumps, translocation detection, etc)
19:11 < chevbird> for automation just about everything we do needs to end up on a liquid handler for atscale production
19:11 < chevbird> so lots of different things
19:11 <@kanzure> chevbird: two main criticisms of your resume; the coursework will probably have to go eventually, and second, your "COMPUTER AND LAB SKILLS" is nice and all, but there's too much space in between the left and right columns, plus not enough space between each row
19:12 < chevbird> i keep hearing that about the coursework
19:13 <@kanzure> i think it's fine at the moment, but in 5 or 10 years, probably not so much
19:13 < chevbird> yea
19:13 <@kanzure> what does LRIG do
19:13 <@kanzure> i have a strong interest in lab automation and open source lab equipment, so i dunno if LRIG is up to anything worthwhile?
19:14 < yashgaroth> two copyedit ones since I like to do that; "Broad Institue", and "production throughout by 400% through..." did you mean throughput, and also consider a synonym for through
19:14 < chevbird> its a bunch of guys that get together for free food and chatting about new vendors and tech and etc
19:14 < chevbird> usually over beer
19:14 <@kanzure> ok cool
19:14 <@kanzure> do any of them build lab automation tools?
19:14 <@kanzure> or do they just buy things
19:14 < chevbird> haha
19:14 < chevbird> ok
19:16 < chevbird> basically buying
19:17 <@kanzure> okay neato
19:17 <@kanzure> there's a regular around here that is building an open source liquid handling machine
19:17 <@kanzure> and he doesn't know any potential customers
19:18 < chevbird> death to agilent
19:19 <@kanzure> chevbird: have you seen http://search.cpan.org/~jcline/Robotics-0.21/lib/Robotics/Tecan.pm
19:20 < chevbird> kanzure: i have not
19:21 < chevbird> looks awesome
19:24 <@kanzure> chevbird: one of the projects in here is a microfluidic dna synthesizer, and we're hoping to do water-in-oil emulsions eventually with it
19:24 <@kanzure> so that's why i was curious about your emulsion experience
19:25 < chevbird> working on something very similar
19:25 < chevbird> and hopefully i get a call back on a job from gnubio, whos whole company is built around that
19:25 <@kanzure> i've heard of gnubio
19:25 <@kanzure> i hate them for calling themselves gnu anything and not being open source, but whatever
19:26 <@kanzure> no copyright/trademark on the animal i guess
19:26 < chevbird> http://www.masshightech.com/stories/2010/05/31/daily32-GnuBio-launches-as-open-source-genome-sequencing-startup.html
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19:26 <@kanzure> nono i said synthesis, not sequencing
19:27 < chevbird> ok fine
19:27 < chevbird> haha
19:27 <@kanzure> but also: i haven't seen any of gnubio's "open source" stuff on the web; have i missed something
19:27 <@kanzure> maybe i just suck at interneting
19:27 < chevbird> they dont have much done yet
19:27 < chevbird> which is why theyre expanding now
19:27 < chevbird> to make good on the promise
19:28 <@kanzure> i see. do they have money?
19:28 < chevbird> id imagine so
19:29 < chevbird> theyre expanding pretty agressively
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19:32 < chevbird> hopefully so agressively that they call me back
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19:45 < n_bentha> So who else is excited for the spacex launch (if it ever happens)?
19:46 < n_bentha> May 19th
19:46 < chevbird> yes
19:47 < ParahSailin> i wish the american regime would have given me a couple million to start a space company rather than giving it to elon musk
19:47 < yashgaroth> his pillows needed to be stuffed with $100 bills, to match his mattress
19:49 < ParahSailin> nasa provided over half the capital in spacex without taking any equity
19:50 < n_bentha> do they have 51%+ of the company's stock?
19:50 < ParahSailin> without taking any equity
19:51 < ParahSailin> no, it was just a free money grant
19:57 < n_bentha> so stupid
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20:14 < ParahSailin> but its private space flight
20:14 < ParahSailin> free market enterprise is progress
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21:09 < joshcryer> NASA's funding to SpaceX is predicated on delivery.
21:09 < joshcryer> ie, SpaceX doesn't get paid unless they deliver.
21:10 < joshcryer> This is in contrast to other companies like the ULA Alliance who got paid to do stuff that they didn't even have to deliver. (See the Ares I-X debacle.)
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21:43 < Mokbortolan_> http://chzscience.files.wordpress.com/2011/11/funny-science-news-experiments-memes-tongue-twister-spider-silk-spigots.jpg\
21:43 < n_bentha> 404 — File not found.
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21:49 <@kanzure> n_bentha: probably because of the slash at the end
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21:51 < n_bentha> thanks kanzure
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22:05 < joshcryer> SIGGRAPH 2012 papers are fucking shit up.
22:05 <@kanzure> joshcryer: in the bad way?
22:06 < joshcryer> In a really sweet way.
22:06 < joshcryer> http://kesen.realtimerendering.com/sig2012.html
22:08 < joshcryer> this one is really cool: http://www.cemyuksel.com/research/stitchmeshes/
22:08 < joshcryer> afk
22:10 <@kanzure> "I think for most startups with good performance metrics, expecting 1/5 of your pitches to convert is a good benchmark."
22:10 <@kanzure> yikes.. 20%?
22:10 <@kanzure> was from http://news.ycombinator.com/item?id=3969252
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22:25 < ParahSailin> wayland is something that is supposedly gonna replace x11?
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--- Log closed Mon May 14 00:00:09 2012