--- Log opened Sat Jun 30 00:00:55 2012 00:10 -!- yashgaroth [~f@cpe-66-27-117-179.san.res.rr.com] has quit [Quit: Leaving] 00:12 < strangewarp> Fox News Qatar... what an enlightening thought 00:16 < strangewarp> ps kanzure: you may want to IP-ban, if you're serious about keeping that guy out 00:17 -!- nmz787 [~Nathan@ool-457e5cbd.dyn.optonline.net] has quit [Quit: Leaving.] 00:27 -!- qnm [~qnm@2001:44b8:3110:f300:208:9bff:fec0:179a] has quit [Ping timeout: 272 seconds] 00:30 -!- qnm [~qnm@2001:44b8:3110:f300:208:9bff:fec0:179a] has joined ##hplusroadmap 00:52 -!- lichen [~lichen@c-76-105-164-184.hsd1.or.comcast.net] has joined ##hplusroadmap 02:00 -!- qnm [~qnm@2001:44b8:3110:f300:208:9bff:fec0:179a] has quit [Ping timeout: 240 seconds] 02:03 -!- qnm [~qnm@2001:44b8:3110:f300:208:9bff:fec0:179a] has joined ##hplusroadmap 02:20 -!- sylph_mako [~mako@14.78.252.27.dyn.cust.vf.net.nz] has joined ##hplusroadmap 03:32 -!- audy [~audy@heyaudy.com] has quit [Quit: ZNC - http://znc.sourceforge.net] 03:35 -!- audy [~audy@heyaudy.com] has joined ##hplusroadmap 03:37 -!- audy [~audy@heyaudy.com] has quit [Client Quit] 03:39 -!- audy [~audy@heyaudy.com] has joined ##hplusroadmap 03:56 -!- klafka1 [~textual@c-67-174-253-229.hsd1.ca.comcast.net] has quit [Quit: Computer has gone to sleep.] 03:57 -!- qnm [~qnm@2001:44b8:3110:f300:208:9bff:fec0:179a] has quit [Ping timeout: 272 seconds] 04:00 -!- qnm [~qnm@2001:44b8:3110:f300:208:9bff:fec0:179a] has joined ##hplusroadmap 04:33 -!- sylph_mako [~mako@14.78.252.27.dyn.cust.vf.net.nz] has quit [Quit: Leaving] 04:51 -!- ThomasEgi [~thomas@panda3d/ThomasEgi] has joined ##hplusroadmap 05:01 -!- nathaniel_ [~nathaniel@reddit/operator/nathaniel] has joined ##hplusroadmap 05:04 -!- nathaniel [~nathaniel@reddit/operator/nathaniel] has quit [Ping timeout: 248 seconds] 05:47 -!- Smith_PHD [~adam@75.105.14.63] has joined ##hplusroadmap 06:03 -!- Vicarious [diepfriet@CAcert/Vicarious] has quit [Ping timeout: 248 seconds] 06:04 -!- Vicarious [diepfriet@CAcert/Vicarious] has joined ##hplusroadmap 06:49 -!- augur [~augur@206.196.184.127] has joined ##hplusroadmap 07:10 -!- augur [~augur@206.196.184.127] has quit [Read error: Connection reset by peer] 07:11 -!- augur [~augur@206.196.184.127] has joined ##hplusroadmap 07:24 -!- atomicfawkes [~jack@75-105-14-63.cust.wildblue.net] has joined ##hplusroadmap 07:34 -!- devrandom [~devrandom@gateway/tor-sasl/niftyzero1] has quit [Ping timeout: 276 seconds] 07:35 -!- Utopiah [~utopiah@unaffiliated/utopiah] has quit [Ping timeout: 265 seconds] 07:39 -!- nathaniel_ [~nathaniel@reddit/operator/nathaniel] has quit [Quit: Leaving] 07:41 -!- Utopiah [~utopiah@rps7452.ovh.net] has joined ##hplusroadmap 07:46 -!- augur_ [~augur@206.196.184.127] has joined ##hplusroadmap 07:46 -!- augur [~augur@206.196.184.127] has quit [Ping timeout: 240 seconds] 08:47 -!- rmcl [~rmcl@99-71-136-35.lightspeed.sndgca.sbcglobal.net] has joined ##hplusroadmap 09:54 -!- klafka [~textual@c-67-174-253-229.hsd1.ca.comcast.net] has joined ##hplusroadmap 10:03 -!- nmz787 [~Nathan@ool-457e5cbd.dyn.optonline.net] has joined ##hplusroadmap 10:22 -!- augur_ [~augur@206.196.184.127] has quit [Remote host closed the connection] 10:44 -!- nmz787 [~Nathan@ool-457e5cbd.dyn.optonline.net] has quit [Quit: Leaving.] 10:48 -!- nmz787 [~Nathan@ool-457e5cbd.dyn.optonline.net] has joined ##hplusroadmap 10:49 -!- AlonzoTG [~atg@dsl092-168-049.wdc2.dsl.speakeasy.net] has joined ##hplusroadmap 10:50 -!- yashgaroth [~f@cpe-66-27-117-179.san.res.rr.com] has joined ##hplusroadmap 11:00 -!- nmz787 [~Nathan@ool-457e5cbd.dyn.optonline.net] has quit [Quit: Leaving.] 11:11 -!- Jaakko96 [~Jaakko@host86-152-7-101.range86-152.btcentralplus.com] has joined ##hplusroadmap 11:17 -!- nathaniel [~nathaniel@reddit/operator/nathaniel] has joined ##hplusroadmap 11:29 -!- Jaakko96 [~Jaakko@host86-152-7-101.range86-152.btcentralplus.com] has quit [Quit: Nettalk6 - www.ntalk.de] 11:36 -!- eudoxia [~eudoxia@r186-52-133-25.dialup.adsl.anteldata.net.uy] has joined ##hplusroadmap 11:40 < neuroscientist> lets get this party started shall we? 11:45 * ThomasEgi hands neuroscientist a party had.. go one 11:45 < ThomasEgi> *on 11:48 -!- archels [~foo@sascha.esrac.ele.tue.nl] has quit [Ping timeout: 246 seconds] 11:58 -!- archels [~foo@sascha.esrac.ele.tue.nl] has joined ##hplusroadmap 12:12 <@kanzure> "you cannot perform an ACH transfer between two individuals" wtf is the point then 12:14 < atomicfawkes> http://www.snopes.com/fraud/phishing/nacha.asp 12:15 < atomicfawkes> Fake ACH Transfer Failure Notifications Spread ZeuS 12:21 <@kanzure> why are you still here 12:21 -!- qnm [~qnm@2001:44b8:3110:f300:208:9bff:fec0:179a] has quit [Ping timeout: 264 seconds] 12:23 < atomicfawkes> ask yourself that same question 12:23 < atomicfawkes> why is anyone here? 12:23 < atomicfawkes> i dont see why you feel the need to attack me for no reason 12:24 < atomicfawkes> so there is no reason NOT to be here 12:24 -!- qnm [~qnm@2001:44b8:3110:f300:208:9bff:fec0:179a] has joined ##hplusroadmap 12:31 < ThomasEgi> the nonusage of doublenegation is strictly prohibited?... 12:32 < atomicfawkes> I went back to molecular crypto today 12:32 < atomicfawkes> using proteins to do math 12:32 < atomicfawkes> in a petri dish 12:32 < atomicfawkes> theres somethign to that 12:32 < atomicfawkes> biocomputers 12:33 < atomicfawkes> humans are good enough that technology is still an accessory 12:34 < atomicfawkes> im workign on a theory that its sort of like leapfrog. 12:34 < atomicfawkes> humans need food and water to survive 12:35 < atomicfawkes> in order for western civlization to survive humans need food, water, clothes, power, internet 12:35 < atomicfawkes> transportation 12:35 < atomicfawkes> the leapfrog comes in when we need the internet and power to survive 12:35 < atomicfawkes> and some of us have even moved beyond that 12:36 < atomicfawkes> or have moved past the point of food and water 12:36 < atomicfawkes> and literally require electricity 12:38 -!- rmcl [~rmcl@99-71-136-35.lightspeed.sndgca.sbcglobal.net] has quit [Quit: rmcl] 13:00 -!- rmcl [~rmcl@cpe-66-27-103-6.san.res.rr.com] has joined ##hplusroadmap 13:11 -!- augur [~augur@206.196.184.127] has joined ##hplusroadmap 13:27 < AlonzoTG> I had a 2 day internet outage recently due to a botched speed upgrade (from 6 to 8 megs down and from 768k to 1meg up) 13:27 < AlonzoTG> I also had an 18 hour power outage due to a hurricane strength thunderstorm that came through last night. 13:28 < AlonzoTG> Because I'm not an upload, neither was fatal. 13:28 < AlonzoTG> =P 13:32 -!- rmcl [~rmcl@cpe-66-27-103-6.san.res.rr.com] has quit [Quit: rmcl] 13:40 < eudoxia> Note to self: computers for uploads should use NVRAM and switch on automatically once they are plugged in 13:42 < atomicfawkes> yeah 94mph was the highest recorded gust last night 13:43 < atomicfawkes> they were saying 80mph in some places 13:43 < atomicfawkes> it was at least 50 here 13:43 < atomicfawkes> trees down 13:43 < atomicfawkes> i thought we were having a tornado 13:43 < atomicfawkes> tornado ally has moved east a little 13:44 < atomicfawkes> and for the fist time in history my area is getting tornadosa 13:44 < atomicfawkes> we had a couple last year 13:44 < atomicfawkes> never before 13:44 < atomicfawkes> one just half a mile from my house here 13:44 < atomicfawkes> i could hear it 13:48 -!- augur [~augur@206.196.184.127] has quit [Read error: Connection reset by peer] 13:48 -!- augur [~augur@206.196.184.127] has joined ##hplusroadmap 13:49 -!- augur [~augur@206.196.184.127] has quit [Read error: Connection reset by peer] 13:49 -!- augur [~augur@206.196.184.127] has joined ##hplusroadmap 13:52 < augur> beep 13:52 < eudoxia> boop 13:54 <@kanzure> hi 13:55 -!- OldCoder_ [~OldCoder_@c-69-181-140-134.hsd1.ca.comcast.net] has quit [Remote host closed the connection] 13:57 -!- OldCoder_ [~OldCoder_@c-69-181-140-134.hsd1.ca.comcast.net] has joined ##hplusroadmap 14:05 < augur> tell me about self-assembly! 14:05 <@kanzure> i think reading anything by anyone named "manu-whatever" at CBA/MIT will give you an okay overview of self-assembly 14:06 <@kanzure> in addition, paul rothemund or erik winfree's stuff can give you an okay overview of dna self-assembly 14:06 <@kanzure> http://dna.caltech.edu/ 14:07 < augur> hm! 14:07 < atomicfawkes> corps in the beltway were hireing up ppl to do protein assembly 14:07 < atomicfawkes> a few years ago 14:07 < atomicfawkes> dna is sort of quantum 14:08 < atomicfawkes> its not exactly binary 14:08 <@kanzure> of course it's not binary. are you a biologist? 14:08 < eudoxia> it's... quaternary? 14:08 < atomicfawkes> i met francis collins at least once 14:08 <@kanzure> eudoxia: uracil sometimes gets in there, actually 14:09 < eudoxia> yeah, that's what I thought, but isn't that for RNA exclusively? 14:09 <@kanzure> eudoxia: and then you have modified nucleotides. anyway, i don't see what quantum anything has to do with the bit representation. 14:09 < atomicfawkes> adn the ciso for the head of all us spy agencies 14:09 < atomicfawkes> ive done many things 14:09 <@kanzure> no i think uracil can get into dna on occassion 14:09 < eudoxia> that's interesting 14:09 <@kanzure> atomicfawkes: can you please refrain from talking about spy agencies, quantum conscious dna, 9/11, or any of the other things i've kicked you for 14:09 <@kanzure> eudoxia: http://www.ncbi.nlm.nih.gov/pubmed/12483510 14:09 <@kanzure> "Uracil in DNA--occurrence, consequences and repair." 14:10 < atomicfawkes> until you come up with another reason 14:10 < atomicfawkes> sure 14:10 <@kanzure> eudoxia: lots of things can go 'wrong' with dna 14:12 < eudoxia> kanzure: you know, the other day I was thinking: our chem teacher showed us a video about DNa where some guy said they stored the sequence in a .txt file, and I thought, "that's inefficient, if you have 4 nucleotide types you can store 4 per char", but this totally fucks that up 14:12 < atomicfawkes> ive been kicked out of a county in mississippi, cody wyoming and atlanta. in mississippi , (reminds me of you) , i asked them on what charges and they told me 'we'll think of something' 14:12 <@kanzure> eudoxia: not really.. your detection method probably only detects the four nucleotides anyway 14:12 < atomicfawkes> i am genuinely interested in human advancement and biology and have a wide range of experince 14:13 < eudoxia> oh good 14:13 <@kanzure> if you were given a strand of church's "unnatural dna" (with the engineered nucleotides for an engineered polymerase), you wouldn't be able to sequence it reliably (without a different sequencing chemistry) 14:13 <@kanzure> atomicfawkes: interest isn't enough to let you troll in here with your wacky noise 14:15 < atomicfawkes> who's trolling 14:15 < eudoxia> so it would just report the closest nucleotide to what's actually there? 14:16 < atomicfawkes> waky noise is a subjective issue, it takes a villiage 14:16 <@kanzure> atomicfawkes: no it doesn't take a village, go away 14:17 < atomicfawkes> you're just hateful 14:17 <@kanzure> eudoxia: depends on your sequencing chemistry, sorry dude 14:17 <@kanzure> atomicfawkes: yes i am 14:21 < ThomasEgi> eudoxia, how bout base64. not as messed up but still a bit more efficient 14:21 <@kanzure> base64 makes it more complicated to do BLAST 14:22 < eudoxia> are you talking about some biochem thing or the encoding scheme 14:22 < ThomasEgi> the actual encoding of the storage. 14:23 < ThomasEgi> anyone ever did ever meassured the entropy of an dna string? like how much it can be compressed with todays algorithms? 14:23 <@kanzure> it can be compressed pretty well if you allow yourself to reference genes and sequences from ncbi's website 14:29 < ThomasEgi> hm. i was more like compressing the whole sequence as it is. without further need of references other than the decompressing algorithm 14:31 -!- Jora [~Jora@24-196-82-58.dhcp.mdsn.wi.charter.com] has joined ##hplusroadmap 14:31 -!- Jora [~Jora@24-196-82-58.dhcp.mdsn.wi.charter.com] has quit [Changing host] 14:31 -!- Jora [~Jora@unaffiliated/jora] has joined ##hplusroadmap 14:35 <@kanzure> ThomasEgi: not sure why you would do that when we already have a global index on the web 14:36 < ThomasEgi> curiosity. and it never hurts to have a complete backup 14:36 <@kanzure> well, as far as i know, it's a few terabytes of data on their ftp server 14:37 <@kanzure> if you can get that down to a few gigs, i'll take a copy 14:37 < ThomasEgi> that is what i was wondering about. how compressible dna information is 14:38 < atomicfawkes> I was referrign to dna in the quantum computing sense (ban me if you like) because its not exactly binary 14:38 < atomicfawkes> so in the means of storing data is exponentially more efficient 14:38 < atomicfawkes> as well as the speed at which its processed 14:39 < atomicfawkes> because you have multiple sets of data instead of multiple cores 14:39 < atomicfawkes> cdma 14:40 <@kanzure> i don't think you're communicating anything meaningful right now. 14:40 < atomicfawkes> you have to think about what im saying 14:40 < atomicfawkes> thats all 14:40 <@kanzure> you're not saying anything. 14:41 < atomicfawkes> AT GC is 2 sets of binary 14:41 < atomicfawkes> processed by the same core 14:41 < atomicfawkes> instead of multiple cores 14:41 <@kanzure> what the fuck is a core 14:41 < atomicfawkes> mitochondria 14:41 <@kanzure> sigh 14:41 < eudoxia> whut 14:42 < yashgaroth> hahaha 14:43 <@kanzure> i don't even know how to describe to you how wrong you are right now 14:44 < atomicfawkes> its an analogy 14:44 < atomicfawkes> it doesnt have to be right 14:44 <@kanzure> no, it's shit and you should leave 14:44 -!- chevbird [~chevbird@209-6-62-26.c3-0.sbo-ubr1.sbo.ma.cable.rcn.com] has joined ##hplusroadmap 14:46 < atomicfawkes> so youre saying that dna isnt a stream of data? 14:47 < atomicfawkes> or that information isnt contained in dna based on the paring of the halves? 14:47 < atomicfawkes> what are you disagreeing with exactly 14:47 < yashgaroth> 1 being 'not exactly binary' does not make something quantum by default 14:48 < yashgaroth> 2 the speed at which dna is written (not copied, mind you) is excruciatingly slow 14:48 < ThomasEgi> atomicfawkes, listening to you.... what you imply is that a 2bit computer is more powerful than a 64bit one^^ 14:48 < yashgaroth> 3 you don't seem to know what a mitochondrion is 14:49 < atomicfawkes> its been a while 14:49 <@kanzure> this is just, not helpful at all 14:49 < ThomasEgi> kanzure, altho i love to disagrre with you, i totaly agree with you on this one 14:51 < atomicfawkes> only quantum in the sense that its not binary 14:51 < atomicfawkes> have you 14:51 -!- mode/##hplusroadmap [+o yashgaroth] by kanzure 14:51 < atomicfawkes> that more states that 1 and 0 14:51 < atomicfawkes> offer exponential opportunities 14:51 < atomicfawkes> for data 14:52 * ThomasEgi greps some popcorn to enjoy the upcomming event 14:52 < atomicfawkes> so with multiple streams of data opposed to multiple cores 14:52 < atomicfawkes> its similar to cellphone technology 14:52 < atomicfawkes> cdma 14:52 < atomicfawkes> code divisional multiple access 14:53 < ThomasEgi> cdma stands for collision detection multiple access. and has little to do with cellphones. 14:53 < atomicfawkes> lol 14:53 < atomicfawkes> cdma was developed by a pianist and a singer 14:53 < atomicfawkes> george antheil and heddy lemar 14:54 < atomicfawkes> and was used to guide torpedos 14:54 < ThomasEgi> seems there are many meanings for cdma. and none belongs into this channel 14:54 < atomicfawkes> dna is code 14:55 < atomicfawkes> id assume that hplus would require modifiying that code 14:55 < atomicfawkes> other wise there is no plus 14:55 <@yashgaroth> *!*@*75*105*14*63* should work well 14:56 < atomicfawkes> its not human road map 14:56 < atomicfawkes> its about how to make a better humanity 14:56 <@kanzure> atomicfawkes: that has nothing to do with quantum mitochondria 14:56 <@kanzure> this isn't about humanity. 14:56 < atomicfawkes> of course not 14:56 <@kanzure> you are not being coherent 14:56 < ThomasEgi> m( 14:59 < atomicfawkes> is it not in the colective interest of this channel to discuss and develop different methods of advancing humanity 14:59 < atomicfawkes> its in the topic 14:59 < atomicfawkes> biohacking 14:59 <@kanzure> nothing you have said today is on-topic 14:59 < atomicfawkes> thers a point to it 15:00 < ThomasEgi> you admit that you are not making sense? 15:00 < ThomasEgi> can't tell if phylosophic, or just confused. 15:06 < atomicfawkes> ThomasEgi, he's admittadly on medication for metal issues, so idk, who knows if he's making sense or not 15:06 < atomicfawkes> we can move past that 15:06 < atomicfawkes> what is the hplusroadmap 15:09 < atomicfawkes> what are the goals of bio hacking, and how should it be directed? 15:09 < atomicfawkes> or directed at all.. 15:10 <@kanzure> Metal issues. 15:11 < eudoxia> was that a typo? 15:12 <@yashgaroth> EDTA therapy, I'm sure 15:15 < atomicfawkes> http://reddit.com/r/Metal/comments/vuvoj+ 15:16 < atomicfawkes> metal issues 15:16 < atomicfawkes> how freudian 15:28 < ThomasEgi> hm metal issues would be indeed a problem. i don't own a lathe, so metalworking is very difficult for me. 15:35 <@kanzure> aha that explains it. another reddit user. :( 15:36 -!- ThomasEgi [~thomas@panda3d/ThomasEgi] has quit [Ping timeout: 240 seconds] 15:43 < chido> good evening gentlemen 15:44 < chido> I gave a talk today at our hackerspace about the DIYbio FBI trip and people liked it 15:47 -!- Jora is now known as jorathebohemian 15:48 -!- ThomasEgi [~thomas@pppdyn-20.stud-ko.rz-online.net] has joined ##hplusroadmap 15:48 -!- ThomasEgi [~thomas@pppdyn-20.stud-ko.rz-online.net] has quit [Changing host] 15:48 -!- ThomasEgi [~thomas@panda3d/ThomasEgi] has joined ##hplusroadmap 15:48 -!- jorathebohemian is now known as Jora 15:49 <@kanzure> chido: neat. any transcript? 15:49 <@kanzure> (i am kidding) 15:51 < chido> kanzure: no, you were dearly missed. and there were words of admiration uttered by the crowd upon me showing them the transcripts you did 15:54 <@kanzure> haha 15:55 < chido> I think there is a videorecording though, but since I gave my talk in my native tongue... I assume that would have been quite a challenge for you to transcribe 15:55 <@kanzure> lots of "dklfasdlkasdflakdfjkal lkdfjladfkadkla akld;kadka;" basically 16:03 -!- eudoxia [~eudoxia@r186-52-133-25.dialup.adsl.anteldata.net.uy] has quit [Quit: Leaving] 16:12 -!- augur [~augur@206.196.184.127] has quit [Remote host closed the connection] 16:34 -!- kvltist [~Kvltist@p5B15736A.dip.t-dialin.net] has joined ##hplusroadmap 16:39 -!- rmcl [~rmcl@99-71-136-35.lightspeed.sndgca.sbcglobal.net] has joined ##hplusroadmap 16:42 -!- chevbird [~chevbird@209-6-62-26.c3-0.sbo-ubr1.sbo.ma.cable.rcn.com] has quit [Quit: Leaving] 16:43 -!- chevbird [~chevbird@209-6-62-26.c3-0.sbo-ubr1.sbo.ma.cable.rcn.com] has joined ##hplusroadmap 16:52 -!- lichen [~lichen@c-76-105-164-184.hsd1.or.comcast.net] has quit [Quit: KVIrc 4.0.2 Insomnia http://www.kvirc.net/] 16:58 <@kanzure> hrmm 16:58 -!- chevbird_ [~chevbird@66-87-82-55.pools.spcsdns.net] has joined ##hplusroadmap 17:02 -!- chevbird [~chevbird@209-6-62-26.c3-0.sbo-ubr1.sbo.ma.cable.rcn.com] has quit [Ping timeout: 244 seconds] 17:07 <@kanzure> http://philip.greenspun.com/careers/women-in-science 17:07 <@kanzure> "For whom does academic science as a career make sense? The picture so far is pretty bleak. The American academic scientist earns less than an airplane mechanic, has less job security than a drummer in a boy band, and works longer hours than a Bolivian silver miner." 17:08 < ThomasEgi> sounds pretty sad 17:09 -!- chevbird [~chevbird@209-6-62-26.c3-0.sbo-ubr1.sbo.ma.cable.rcn.com] has joined ##hplusroadmap 17:09 < Urchin> it's got to the point where grad students are forming unions, afaik 17:09 -!- chevbird_ [~chevbird@66-87-82-55.pools.spcsdns.net] has quit [Ping timeout: 244 seconds] 17:10 -!- chevbird_ [~chevbird@66-87-86-253.pools.spcsdns.net] has joined ##hplusroadmap 17:10 < brownies> they are? 17:11 < Urchin> why is it so hard for some people to accept that computation causes entropy? 17:11 < brownies> also, what does the author have against boy bands? 17:11 < Urchin> yes, afaik 17:11 < brownies> interesting. 17:11 -!- OldCoder_ [~OldCoder_@c-69-181-140-134.hsd1.ca.comcast.net] has quit [Remote host closed the connection] 17:12 -!- chevbird_ [~chevbird@66-87-86-253.pools.spcsdns.net] has quit [Remote host closed the connection] 17:12 -!- chevbird_ [~chevbird@66-87-86-253.pools.spcsdns.net] has joined ##hplusroadmap 17:14 -!- chevbird [~chevbird@209-6-62-26.c3-0.sbo-ubr1.sbo.ma.cable.rcn.com] has quit [Ping timeout: 244 seconds] 17:15 -!- OldCoder_ [~OldCoder_@c-69-181-140-134.hsd1.ca.comcast.net] has joined ##hplusroadmap 17:17 <@kanzure> yeah i'd like to see the grad student unions 17:17 <@kanzure> i haven't seen those before. i know there are 'graduate student associations' but they are never unions (they are just "how to interface with the dean" or something) 17:19 < brownies> don't they just... throw parties? what does a student association do, anyway? 17:21 -!- chevbird_ [~chevbird@66-87-86-253.pools.spcsdns.net] has quit [Quit: AndroIRC - Android IRC Client ( http://www.androirc.com )] 17:21 -!- chevbird [~chevbird@66-87-86-253.pools.spcsdns.net] has joined ##hplusroadmap 17:23 -!- chevbird [~chevbird@66-87-86-253.pools.spcsdns.net] has quit [Read error: Connection reset by peer] 17:24 -!- chevbird_ [~chevbird@static-72-248-51-218.ma.onecommunications.net] has joined ##hplusroadmap 17:28 <@kanzure> brownies: so i know that page is heavily biased towards academic scientists, but i'm still curious how "scientists getting paid more" might come about 17:29 <@kanzure> there's not really too much competition between pharma companies to hire people because they all have the same base set of skills (mostly) 17:29 <@kanzure> and if they need something specific, they just buy the patent and the lab that was associated with it 17:29 <@kanzure> (well, they don't buy the lab, they buy the company that was spun out of the lab) 17:30 * atomicfawkes checks gilead stock 17:32 <@yashgaroth> nah occasionally they'll buy the lab, they just fire everyone 17:32 < chevbird_> Haha 17:33 < brownies> heh, article does make some good points 17:33 < brownies> what about option 3: buy the patent, hire some underpaid college grads who have proven they can add two numbers together, and foot the bill to train them yourself 17:34 < ParahSailin_> grad students unionizing? 17:34 < brownies> kanzure: in any case, you've caught me at a relatively pessimistic time as far as my viewpoint on all this 17:35 < brownies> the other day, i came to accept that even *educating* everyone to a reasonable level of scientific competence has never had a viable business model behind it 17:36 < brownies> kanzure: so for ideas on how to actually increase the economic value of the *output* of that economically unsustainable system... well, that seems rather ambitious. 17:36 < brownies> (i am open to... in fact i would love refutation on... my pessimism here) 17:44 -!- OldCoder_ [~OldCoder_@c-69-181-140-134.hsd1.ca.comcast.net] has quit [Read error: Connection reset by peer] 17:52 -!- OldCoder_ [~OldCoder_@c-69-181-140-134.hsd1.ca.comcast.net] has joined ##hplusroadmap 18:04 -!- chevbird_ [~chevbird@static-72-248-51-218.ma.onecommunications.net] has quit [Ping timeout: 246 seconds] 18:17 -!- chevbird [~chevbird@static-72-248-51-218.ma.onecommunications.net] has joined ##hplusroadmap 18:28 -!- ThomasEgi [~thomas@panda3d/ThomasEgi] has quit [Remote host closed the connection] 18:32 -!- chevbird_ [~chevbird@66-87-83-96.pools.spcsdns.net] has joined ##hplusroadmap 18:33 -!- chevbird [~chevbird@static-72-248-51-218.ma.onecommunications.net] has quit [Read error: Connection reset by peer] 18:37 -!- chevbird_ [~chevbird@66-87-83-96.pools.spcsdns.net] has quit [Ping timeout: 246 seconds] 18:40 -!- strages_home [~strages@adsl-98-67-166-99.shv.bellsouth.net] has quit [Quit: Lost terminal] 18:40 <@kanzure> brownies: or changing the economic output of these research-capable individuals 18:40 <@kanzure> i'm not suggesting that research should be bent to meet company goals 18:40 <@kanzure> but rather that the same set of skills can be repurposed for other tasks 18:44 -!- chevbird [~chevbird@static-72-248-51-218.ma.onecommunications.net] has joined ##hplusroadmap 19:00 -!- chevbird_ [~chevbird@66-87-84-122.pools.spcsdns.net] has joined ##hplusroadmap 19:03 -!- chevbird [~chevbird@static-72-248-51-218.ma.onecommunications.net] has quit [Ping timeout: 246 seconds] 19:03 -!- augur [~augur@206.196.184.127] has joined ##hplusroadmap 19:08 -!- augur [~augur@206.196.184.127] has quit [Remote host closed the connection] 19:14 -!- chevbird_ [~chevbird@66-87-84-122.pools.spcsdns.net] has quit [Read error: Connection reset by peer] 19:15 -!- augur [~augur@206.196.184.127] has joined ##hplusroadmap 19:16 <@kanzure> http://desmond.yfrog.com/Himg814/scaled.php?tn=0&server=814&filename=wibwj.jpg&xsize=640&ysize=640 19:16 <@kanzure> it's a little weird seeing smari mccarthy next to a picture of tom cruise in the same magazine 19:18 -!- augur [~augur@206.196.184.127] has quit [Remote host closed the connection] 19:21 < brownies> kanzure: tasks such as what? 19:22 < brownies> part of the problem here, btw, is that "research" unfortunately encompasses "slightly-skilled manual labor" which realistically should all be done by robots within the next 5-10 years 19:24 <@kanzure> you mean "should have been done by robots 15 years ago" 19:24 <@kanzure> well i guess if you have bunches of robots the task of researchers then becomes more like programming 19:24 <@yashgaroth> actually that'd be a great way to get scientists to unionize 19:25 <@kanzure> what? automation envy? 19:25 <@yashgaroth> fear of the industry becoming automated 19:25 <@kanzure> no we want the industry automated 19:25 <@kanzure> ... don't we? 19:25 <@yashgaroth> and you'll get that scientist union as well, it's win/win 19:26 <@yashgaroth> shit there's few enough good scientists as it is, the number who know some programming is even less...I'll be practically guaranteed employment 19:27 < ParahSailin_> as long as patents keep the cost of the equipment up, your labor market for science is gonna be out of whack 19:27 < brownies> good point. now that we're dramatically inflating the value of a BS by giving one to approximately everyone, it's safe to assume that PhDs will drop in value as well? 19:27 <@yashgaroth> there's been a huge increase in bio PhDs compared to any other field 19:28 < ParahSailin_> and as long as nih is the biggest source of money 19:28 <@kanzure> phds have always varied wildly.. "interview 100 people and assemble some graphs" gets you a phd sometimes, but not always 19:28 <@kanzure> so i dunno if you can claim that more people getting phds means less quality or something 19:29 <@kanzure> if anything it just means that your curves will have more datapoints or something 19:29 -!- chevbird_ [~chevbird@66-87-81-229.pools.spcsdns.net] has joined ##hplusroadmap 19:29 <@yashgaroth> I'm not saying that, just that it's becoming more standard for the industry to have a phd/postdoc 19:29 <@kanzure> yeah, because they have 100's of thousands of people to hire from and not that many jobs 19:29 <@yashgaroth> 20 years ago you could eventually become a VP with just a BS, now it's pretty well impossible 19:30 <@kanzure> i mean, if the minimum profitable company size that can hire phds like crazy is the size of merck, you're kinda screwed on the employment side ;) 19:30 <@kanzure> so, experiment/project design is already "like" "programming" 19:31 <@kanzure> you design your workflows and then put material through the pipeline and look at the results 19:31 <@kanzure> except.. you also do lots of manual labor in between and sometimes forget the big picture 19:31 <@kanzure> perhaps you were saying (about the programming comment above) that these guys are bad at project design, which i could believe 19:32 <@yashgaroth> me, I just meant computer expertise in general...but yes often scientists are bad at project design as well 19:33 <@kanzure> "we'll fly to the amazon, collect some samples, centrifuge randomly and run gels until we find something that works, then we'll do freeze fracture crystallography and pray we see something" (hrm i guess this isn't an entirely bad project design) 19:34 -!- mode/##hplusroadmap [+b *!*@*75*105*14*63*] by yashgaroth 19:34 <@kanzure> i definitely think that researchers could be told "make a research plan to defeat alzheimers" and you could get interesting results 19:35 <@kanzure> this is what e.g. the myelin repair foundation does (although, they hired people to write that roadmap for them, and then got academic labs to sign on for different parts) 19:36 <@yashgaroth> that's how it usually goes, though normally it's "find an antibody that will bind to X target with >Y affinity, you have one year" 19:37 <@yashgaroth> a plan for defeating alzheimers is 'give me 100 billion dollars' 19:37 <@kanzure> pfft not quite. 19:37 <@yashgaroth> ok 50 billion, final offer 19:37 <@kanzure> i think they are operating with $20-$25M 19:38 <@kanzure> 2~ 19:38 <@kanzure> http://www.myelinrepair.org/ 19:38 <@kanzure> "Your gift today will help us reach several myelin repair Phase I Clinical Trials by 2014 and a myelin repair drug to reach patients by 2019." hmm.. 19:38 <@kanzure> http://www.myelinrepair.org/research_model/ 19:39 <@kanzure> "Our accomplishments to date include: Publication of more than 100 scientific articles and reviews in peer-reviewed journals" wtf 19:39 <@kanzure> "More than $45 million raised to support potential myelin repair" 19:40 <@yashgaroth> how does "addressing every phase in the drug discovery process" "shorten[ing] the time to patient treatments" 19:40 <@kanzure> haha 19:40 <@kanzure> yes so they are obviously a bit cocky 19:40 <@kanzure> their "novel idea" is "have someone steering the ship" 19:40 <@yashgaroth> publishing a hundred papers also seems to go against fast development 19:41 <@kanzure> i think the academic labs are incentivized to do it based on the work they have done with this org 19:41 <@kanzure> they may or may not be pressuring for that 19:41 <@kanzure> anyway, it's obvious that there are many improvements that could be made to their process, but my point in bringing them up is that it's an alternative way of putting researchers to work 19:42 <@kanzure> SENS is another example, although aging is difficult to measure in the first place 19:42 <@yashgaroth> oh definitely, even with all the posturing it'll probably work better than the traditional models 19:45 -!- chevbird_ [~chevbird@66-87-81-229.pools.spcsdns.net] has quit [Ping timeout: 264 seconds] 19:45 < ParahSailin_> i wonder what sens is doing 19:45 < ParahSailin_> did you see any of those guys in the bay area when you were there? 19:50 -!- rmcl [~rmcl@99-71-136-35.lightspeed.sndgca.sbcglobal.net] has quit [Quit: rmcl] 19:58 -!- Jora [~Jora@unaffiliated/jora] has quit [Quit: Leaving] 20:03 < brownies> how can a scientist not know how to design an experiment? 20:03 -!- OldCoder_ [~OldCoder_@c-69-181-140-134.hsd1.ca.comcast.net] has quit [Quit: Leaving] 20:04 <@yashgaroth> an experiment is one thing, a whole project is another 20:18 -!- OldCoder_ [~OldCoder_@c-69-181-140-134.hsd1.ca.comcast.net] has joined ##hplusroadmap 20:55 <@kanzure> brownies: there are lab researchers who have job descriptions that are effectively "mix these things together every day to make gels for the older students" 20:56 <@kanzure> "god damn it bryan stop using the good mix" 20:57 < brownies> so they literally do the same thing as my blender 20:58 < brownies> but they cost $30,000 per year instead of $500 20:58 < brownies> i'm just kidding, i don't own a blender. i use a 50cent fork to mash things into a bowl. 20:58 < brownies> kanzure: why do they... have jobs... 21:20 -!- klafka [~textual@c-67-174-253-229.hsd1.ca.comcast.net] has quit [Quit: Computer has gone to sleep.] 21:38 -!- klafka [~textual@c-67-174-253-229.hsd1.ca.comcast.net] has joined ##hplusroadmap 21:39 -!- nathaniel_ [~nathaniel@reddit/operator/nathaniel] has joined ##hplusroadmap 21:40 -!- nathaniel [~nathaniel@reddit/operator/nathaniel] has quit [Read error: Connection reset by peer] 21:41 -!- chevbird [~chevbird@209-6-62-26.c3-0.sbo-ubr1.sbo.ma.cable.rcn.com] has joined ##hplusroadmap 21:51 <@kanzure> brownies: "because i always wanted to do research" 21:59 < brownies> kanzure: no, i mean, why did their employer think paying them to do the job of a blender was a good idea 22:01 < brownies> as opposed to buying a blender, which would be 1000x more cost-effective 22:01 < brownies> or, you know, a Science Blender, which is probably 10x the price, but would still be 100x more cost-effective 22:02 <@kanzure> because an undergrad is smarter than a blender? 22:02 * kanzure isn't so sure about this statement 22:43 < JayDugger> Because their employer had $30,000 in the budget which they would later lose if they didn't spend it on something. Justifying one manual blender (undergrad) takes less effort than justifying sixty automatic blenders. 23:05 -!- devrandom [~devrandom@gateway/tor-sasl/niftyzero1] has joined ##hplusroadmap 23:10 -!- lichen [~lichen@c-76-105-164-184.hsd1.or.comcast.net] has joined ##hplusroadmap 23:10 -!- atomicfawkes [~jack@75-105-14-63.cust.wildblue.net] has quit [Read error: Connection reset by peer] 23:10 -!- Smith_PHD [~adam@75.105.14.63] has quit [Ping timeout: 246 seconds] 23:12 -!- neuroscientist [4b690e3f@gateway/web/freenode/ip.75.105.14.63] has quit [Ping timeout: 245 seconds] --- Log closed Sun Jul 01 00:00:55 2012