--- Log opened Mon Jan 21 00:00:36 2013
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01:14 < eleitl> good morning
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01:41 <@kanzure> eleitl: hi
01:41 < eleitl> rehi
02:08 < nmz787> hi
02:08 < nmz787> eleitl: Dr. Ramsey,
02:08 < nmz787> I've recently moved to Hillsboro, OR, and even toured the FEI NanoPort
02:08 < nmz787> Showroom last week with the local ACS chapter. I applied to the
02:08 < nmz787> Chemistry Ph.D. program at Portland State University, and I'd like to
02:08 < nmz787> focus on optimizing high-throughput DNA synthesis on a micro or
02:08 < nmz787> nano-fluidic platform.
02:08 < nmz787> I was told by a professor there, Dr. Albert S Benight, that I'd have
02:08 < nmz787> to find a funding if I wanted to do my own project. I've searched on
02:08 < nmz787> grants.gov and think I might be able to fit into some biodefense area,
02:08 < nmz787> making DNA primers de-novo for portable bioagent detection or
02:08 < nmz787> something, but I don't know where to look otherwise.
02:08 < nmz787> Do you have any ideas?
02:08 < nmz787> whoops
02:08 < nmz787> wrong paste buffer
02:08 < eleitl> np
02:09 < nmz787> i responded to you on diybio eleitl
02:09 < eleitl> Thanks, Nathan!
02:10 < eleitl> not sure the materials can take, e.g. DMSO/ethanediol/DMF are very good solvents for many polymers
02:11 < eleitl> microfluidics would work well, but it has to be glass/ceramics/metal
02:11 < eleitl> I was thinking about driving a valve with PWM
02:11 < eleitl> mixing via duty cycle
02:12 < eleitl> then, pipe it through nonlinear mixer
02:14 < nmz787> you can do glass microfluidics
02:14 < eleitl> yes, but not with the stuff we have
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02:15 < nmz787> eleitl: http://nathanmccorkle.com/pdf/Rapid%20prototyping%20of%20glass-based%20micro%ef%ac%82uidic%20chips%20utilizing%20two-pass%20defocused%20CO2%20laser%20beam%20method.pdf
02:15 < nmz787> CO2 laser
02:16 < eleitl> we don't have a laser, either
02:16 < eleitl> we need to buy a number of project-related items
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02:16 < eleitl> CCC has a makerspace, but I think it's pretty barebones
02:16 < nmz787> ahh, I just saw a link for a place that was charging $35/hour of CO2 laser time
02:16 < eleitl> not sure, need to check
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04:12  * eudoxia checks the logs
04:12 < eudoxia> i'm glad kim suozzi made it
04:12 < eudoxia> and she got to alcor instead of ci
04:21 < eleitl> I'm also glad
04:21 < eleitl> I hope the tumor did not destroy too much
04:23 < eudoxia> we'll have to wait for the report
04:23 < eudoxia> then she goes on the list :(
04:24 < eleitl> I've seen her original comment on reddit
04:24 < eleitl> thought -- damn, another one of these hopeless cases
04:25 < eleitl> glad milk of human kindness still hasn't run out
04:26 < eleitl> http://www.jove.com/ <-- have been living under a rock, first time I see this
04:32 < eudoxia> i thought she was gonna make it to CI
04:32 < eudoxia> then ben best would do what he did to Henderson or something
04:33 < eudoxia> absolutely horrifying
04:41 < eleitl> are you reading the new cryonet?
04:41 < eudoxia> ocassionally
04:41 < eleitl> marta sandberg is rapidly becoming a major troll
04:41 < eudoxia> ocasionally*
04:41 < eleitl> are you actually from uruguay?
04:42 < eudoxia> oh i noticed
04:42 < eudoxia> and yes
04:42 < eleitl> which part? big city?
04:42 < eudoxia> montevideo, moderately
04:42 < eleitl> do you like it there?
04:43 < eudoxia> it's rather nice
04:43 < eudoxia> still planning to escape as soon as possible
04:43 < eleitl> some people consider uruguay a potential location to emigrate to
04:44 < eudoxia> because it will be relatively untouched when the Happening happens, or some other reason?
04:45 < eleitl> does it get very hot in the summer?
04:45 < eudoxia> not australia hot
04:45 < eudoxia> right now its kind of chilly
04:46 < eleitl> any technology scene there? what does a hacker do in montevideo?
04:47 < eudoxia> well there's a pycon
04:48 < eudoxia> and the engineering uni hosts a robot sumo every year
04:48 < eudoxia> and that's about it
04:48 < eleitl> where woult you escape to, if you could? bay area?
04:49 < eudoxia> any part of america that's not too expensive or too baby jesus-y
04:49 < eudoxia> america = US
04:50 < eleitl> I see
04:50 < eleitl> I would probably move to .no or .ch, if I could
04:52 < eudoxia> .ch seems nice
04:53 < eudoxia> it has the LHC and no crime
04:55 < eudoxia> my godmother keeps telling me i should go study at the KTH
04:56 < eudoxia> where she went
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05:00 < eleitl> ETH?
05:00 < eleitl> nice place
05:00 < eleitl> Eidgenoessische Technische Hochschule
05:01 < eudoxia> no the http://en.wikipedia.org/wiki/Royal_Institute_of_Technology
05:01 < eleitl> oh, .se
05:01 < eleitl> Ander's place
05:01 < eleitl> Anders'
05:02 < eleitl> damn, it's down
05:02 < eudoxia> oh god aleph.se is down
05:03 < eleitl> yes, I just noticed
05:03 < eudoxia> the end times are upon us
05:03 < eudoxia> well actually it happens from time to time
05:03 < eudoxia> i always think "this is it, it's down for good"
05:04 < eleitl> state:            deactivated
05:04 < eleitl> domain:           aleph.se
05:04 < eleitl> deactivationdate: 2013-01-21
05:04 < eleitl> date_to_delete:   2013-03-22
05:04 < eleitl> date_to_release:  2013-03-29
05:04 < eudoxia> this is it
05:05 < eudoxia> 1996 - 2013
05:05 < eleitl> will you ping him I should I do it?
05:06 < eudoxia> he knows you
05:06 < eleitl> great, we've got another 500 EUR budget for purchases approved
05:06 < eleitl> I'll ping him, then.
05:06 < eudoxia> well at least the Archive has it
05:06 < eudoxia> and i recursively downloaded everything a while ago
05:06 < eudoxia> or did kanz do that...
05:07 < eudoxia> http://diyhpl.us/~bryan/irc/anders/backup_anders.tar.gz
05:08 < eleitl> did you knew of jove.com before?
05:09 < eudoxia> nope
05:09 < eleitl> ok, then I haven't completely jumped the shark yet
05:11 < eleitl> eudoxia, do you have an OpenQwaq account?
05:11 < eudoxia> no
05:11 < eudoxia> that's where all the cool extropians meet up?
05:11 < eleitl> do you need one?
05:12 < eleitl> it's Giulio Prisco's server,
05:12 < eleitl> Ron Teitelbaum allows us to use it for events, and such
05:13 < eleitl> I can invite you if you give me a working email address
05:14 < eleitl> thanks, invite sent
05:14 < eudoxia> thanks
05:14 < eleitl> clients work on windows, OS X, and Linux, latter only somewhat
05:14 < eleitl> the login details should be in the mail
05:14 < eudoxia> that's the same place where ken hayworth made that talk about the atlum right?
05:15 < eleitl> right
05:15 < eudoxia> or is it 'did'...
05:15 < eleitl> it has very good audio and video conferencing, especially if you have a headset
05:15 < eleitl> are you win, os x or linux?
05:15 < eudoxia> linux, and i have a yellowed microsoft and headphones :3
05:16 < eleitl> not sure the linux client would do decent codecs
05:16 < eleitl> just try it, I guess
05:16 < eudoxia> i have win7 on the other partition
05:16 < eleitl> win7 works good
05:17 < eleitl> http://code.google.com/p/openqwaq/downloads/list <-- looks a bit long in the tooth
05:17 < eleitl> not sure the 3dicc client is fresher
05:17 < eleitl> use the 3dicc client unless told otherwise
05:18 < eleitl> this technology is based on Smalltalk (Squeak)/OpenCroquet/OpenCobalt/TelePlace etc.
05:18 < eudoxia> i heard
05:18 < eleitl> they're rewriting it in JavaScript, so that it will run in a browser
05:18 < eleitl> not sure it's a smart idea
05:18 < eudoxia> never imagined squeak being used for something serious
05:19 < eudoxia> wait i was thinking about something else
05:19 < eleitl> all the Smalltalk coders are pretty much dead, it seems
05:20 < eleitl> I'm in-world, but at work, so no video, and not a full presence there
05:42 < eleitl> It is nice to see that both of you reacted within 3 minutes of each other. True friends keep an eye on each other's domains :-)
05:42 < eleitl> I think it is a minor payment bug, occasionally I do not get the bills in time in England. I have emailed FSData, my Swedish ISP.
05:42 < eleitl> Have no fear, aleph will be back!
05:42 < eleitl> </anders>
05:44 < eudoxia> i gotta say we have a better response time than a NATO early warning station
05:45 < eleitl> :)
05:47 < eleitl> our co-worker is from Peru, she hasn't been to Montevideo but has seen it from Buenos Aires once
05:47 < eleitl> according to Google, Uruguay looks really nice
05:48 < eudoxia> oh yes
05:48 < eudoxia> a peruvian cryonicist? that's fairly new
05:49 < eleitl> no, she does Java at my dayjob, InfoChem GmbH
05:49  * eleitl is at the accursed saltimes
05:49 < eleitl> saltmines even
05:50 < eudoxia> on the subject of chemistry
05:50 < eudoxia> have you seen github.com/kanzure/nanoengineer
05:51 < eleitl> I see it now. What new is there?
05:52 < eudoxia> kanz is trying to bring it back, an kirka/elfion managed to run it on linux
05:52 < eleitl> 64 bit?
05:52 < eudoxia> i think so
05:52 < eleitl> I have 12.04 at home, I should try it sometime
05:53 < eleitl> it would be great to have a bunch of packages, or even a depository
05:53 < eudoxia> for molecular machine parts?
05:53 < eleitl> no, just for nanoengineer
05:53 < eudoxia> oh like a deb package
05:53 < eleitl> of course a parts depository would be great, too
05:54 < eleitl> a kind of molecular logo/macros with standard interfaces
05:55 < eleitl> I'll go tell Perry, though he probably already knows
05:56 < eudoxia> it might be possible to, as kirka suggested, abstract some machines into blocks with only external bondpoints
05:56 < eudoxia> might need a specialized simulator thoguh
05:57 < eleitl> you need a drag forcefield, which is basically bitblt at voxel level, with collision detection
05:57 < eleitl> that's the only way to drag big blocks quickly
06:00 < eleitl> dammit, I don't even have a working account for perry anymore
06:00 < eleitl> jis.mit.edu bounces
06:04 < eleitl> which kind of Internet hoster do you use, eudoxia? Or just a regular ISP?
06:05 < eudoxia> regular
06:06 < eleitl> colocation in uruguay is probably a bit expensive
06:07 < eleitl> in fact, since my hoster started charging rent for IP space, I'll be moving kit and kaboodle to a local hoster
06:19 < eleitl> how likely do you think is the 2030 peak? http://www.smithsonianmag.com/science-nature/Looking-Back-on-the-Limits-of-Growth.html
06:20 < eleitl> the curves look like it could shift more towards 2040, but that is too far to be very accurate
06:22 < eudoxia> undersea mining will hold back the Happening for a few years
06:22 < eleitl> if we're energy-limited, then EROEI going to shit then new fossil is worth much old than the less
06:23 < eleitl> we've gone from 100:1 to 25:1 and lower.
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06:25 < eudoxia> we're gonna miss oil
06:27 < eleitl> we already do
06:27 < eleitl> things would look a lot prettier with 20 USD/barrel right now
06:28 < eleitl> on the other hand, Chinese would really need axes to cut through the smog, then
06:28 < eudoxia> haha
06:28 < eudoxia> it's rather sad
06:29 < eleitl> friends go there yearly, for visa reasons, and they have to live smack in Peking. With kids. Not fun.
06:30 < eudoxia> maybe it will be an incentive to speed up the thorium reactor project
06:30 < eleitl> if it's feasible, it would take too long
06:31 < eleitl> min 30 years
06:31 < eleitl> assuming it's feasible, which we don't know
06:31 < eleitl> too risky
06:31 < eleitl> I do really think uruguay will be far enough from all the crap that's going to go down
06:32 < eleitl> South America and Oz/Kiwiland will probably sit quite pretty
06:32 < eudoxia> >Its ultimate target is to develop a pilot scale thorium based molten salt nuclear reactor in 20 years.
06:32 < eudoxia> oh come on china you can do better
06:32 < eleitl> no, nuclear tech doesn't happen quickly
06:33 < eleitl> 20 years is already more ambitious, and I doubt they can pull it off without sacrificing something
06:33 < eleitl> THTR in Germany was shut down due to a series of technical problems, and they're starting with a graphite ball pile
06:33 < eleitl> if they run into difficulties there, chances are they won't do MSR at all
06:33 < archels> Do you think ITER is going to work out, eleitl?
06:34 < eleitl> plus, there's a problem with U233 inventory. You need some 2-3 tons in-core.
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06:34 < eleitl> You might be able to kickstart a thorium fuelcycle breeder with Pu-239 of which there's a metric crapload, but I don't know.
06:35 < eleitl> let's say we need 1000 reactors/year, that's some 3000 tons of Pu-239.
06:35 < eleitl> that assuming you can build 1000 ~GW reactors/year.
06:35 < eudoxia> hm
06:35 < eudoxia> all those cold war era icmbs aren't gonna cut it
06:36 < eleitl> wouldn't work with current pressurized water type at all
06:36 < eudoxia> ICBMs*
06:36 < eleitl> you'll probably have to reprocess all the spent fuel rods
06:37 < eudoxia> i'm gonna send these logs to my friend who is a thorium friend
06:37 < eudoxia> freak*
06:37 < eleitl> http://www.ccnr.org/plute_inventory_99.html <-- pure Pu is really rare, so you have to reprocess spent fuel
06:38 < eleitl> that is also a bottleneck
06:38 < JayDugger> Good morning, everyone.
06:39 < eleitl> good morning
06:39 < eleitl> long time no talk
06:39 < JayDugger> Marriage and a job will do that. :)
06:39 < eleitl> http://atomicinsights.com/2012/06/there-are-three-superfuels-uranium-thorium-and-plutonium.html
06:40 < eleitl> ... No, you have this backwards.  Fast-spectrum U-Pu reactors need high fissionable inventories due to the low fission cross-section at high energies; despite high breeding ratios (1.22 for PRISM) if you are only producing 0.22 additional ton of Pu out of ~7.5 tons total fuel-cycle inventory (in-core, cooling and reprocessing), your rate of increase is under 3%/yr and your doubling time is upwards of 25 years.
06:40 < eleitl> LFTR can apparently hit breeding ratios of 1.05-1.07 at reasonable cost, and has no inventory requirement for cooling or fabrication.  More to the point, the thermal spectrum reactor has a low fissionable inventory; it can have a burnup of 80-100% per year.  Increase at 4%/year doubles in 17 years, 5.6%/year doubles in 12.5 years, 7%/year takes 10.
06:40 < JayDugger> And then I had to quickly catch up on the logs, too.
06:40 < eleitl> This still leaves us with the Pu/Am/Cm from a host of sources, even if a substantial amount of it is burned as the starting fuel charges for LFTRs.  Fast-spectrum reactors will get rid of it, burn our abundant supply of DU that we should not waste, and also take the waste Np-238 that LFTRs are inevitably going to have to do something with.  The two go hand in hand.
06:41 < eleitl> Not sure what to make of it, atomicinsights is a worthless blog usually.
06:41 < eleitl> in any case you won't get the scale up kinetics, even if it would all work, which we don't know
06:42 < eleitl> I'm afraid we now have to use the only technology we already have, and which can be scaled up quickly
06:43 < eleitl> archels, I think ITER will be canceled, or delayed indefinitely
06:43 < eleitl> very little money left
06:45 < archels> I didn't know it was in such stormy weather. Hard to keep up a project with so many stakeholders over the course of a few decades, I guess.
06:45 < archels> NIF suffered the same fate, last I heard
06:45 < eudoxia> fusion will always be 50 years away
06:45 < eleitl> they did not plan with the current economic winter, which I fear will be semi-permanent
06:46 < eleitl> if we have zero growth or outright contraction for the next 30-40 years, most ambitious projects will be killed
06:46 < eleitl> this includes space
06:46 < eleitl> not a future I grew up expecting
06:47 < archels> The NIC officially ended on September 30, 2012 without achieving ignition. According to numerous articles in the press, Congress is concerned about the project's progress and funding arguments may begin anew.[106][107][108] These reports also suggest that NIF will shift its focus away from ignition back toward materials research.
06:48 < eudoxia> National Ignition Facility is quite the kickin' name
06:49 < eleitl> apparently inertial confinement hit unexpected physics
06:49 < eleitl> just as tokamaks did
06:49 < eleitl> nature doesn't want us to win easily
06:51 < eleitl> where are you now, JayDugger?
06:52 < JayDugger> Texas, just north of Dallas.
06:52 < JayDugger> No more traveling for me. The job's mindless, but steady, and strictly 40 hrs/week.
06:52 < JayDugger> Much better than when last we spoke.
06:53 < eleitl> Same thing here.
06:53 < JayDugger> Job-wise, I assume?
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06:53 < eleitl> I try to make it more interesting, by myself.
06:53 < eleitl> Yes. We've also started a local cryonics lab, which takes up a lot of time.
06:54 < eleitl> Will be writing SENS grant applications in a week or two.
06:54 < JayDugger> Good and good!
06:54 < eleitl> we burn through 1 kEUR/month just for rent, need to cross-fund this, and time-share the place.
07:01 < eleitl> apart from that we're doing some Zero State things, which might or might not succeed
07:02 < JayDugger> I haven't heard of Zero State.
07:02 < eudoxia> i heard a little
07:02 < eleitl> it's a new organization http://zerostate.net/
07:03 < JayDugger> Saw that in the Google results, I'll look.
07:03 < eudoxia> it looked a tiny bit cultish, but i haven't looked into it
07:03 < eleitl> we've had a meeting in May at my place last year, but it's mostly UK based
07:03 < eleitl> yeah, it has to be somewhat cultish to be sticky
07:04 < eleitl> it's basically a variation on the transhumanist memeplex packaging
07:04 < eleitl> ExI tanked, but this doesn't mean it's intrinsically nonsticky
07:04 < eudoxia> and something called kalkinism
07:05 < eleitl> the founder's nym is Amon Kalkin
07:05 < eudoxia> i think that's what set off my cult alarm
07:05 < eleitl> mine, too :)
07:06 < eudoxia> oh i thought that was his legal name, like he'd changed it
07:06 < eleitl> there are a number of projects, one of them could be even quite successfull
07:06 < eleitl> but, nobody to know what it is ;)
07:06 < eudoxia> the classifier in my head reported 3.5 Rachel Haywires of cultism
07:07 < eleitl> is that a logarithmic scale?
07:07 < eudoxia> no
07:10 < eleitl> Rachel seems to be into emo transhumanism
07:10 < eleitl> I must admit I do not care much for that
07:10 < eudoxia> she used to be the editor of h+ magazine
07:10 < eudoxia> the horro
07:10 < eudoxia> horror*
07:11 < eleitl> I haven't touched anything WTA in a long time
07:12 < eudoxia> you haven't missed anything of value
07:12 < eleitl> I know, I'm actively staying away
07:24 < eleitl> by the way, Giulio is also in-world, and Natasha will be coming
07:26 < eleitl> JayDugger, have you used OpenQwaq or Teleplace?
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07:39 < eleitl> whoah, a quarter-second ping to eudoxia
07:41 < eleitl> panax seems to hail from florida
07:46 < eleitl> any of you do DIYbio?
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07:49 < eleitl> the antiperks of hailing from GMT+1, I guess.
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07:59 < eleitl> rehi eudoxia
07:59 < eudoxia> hi
07:59 < eleitl> I've got a 254 ms ping to you from Nuremberg
08:00 < eleitl> but extremely constant. traceroute shows 13 hops.
08:00 < eudoxia> work internet, probably accounts for 25% of this country's bandwidth
08:01 < eleitl> connection looks good
08:01 < eleitl> I've had to resort to reading imgur, out of boredom
08:02 < eudoxia> but it's monday. xkcd, smbc, whomp all update
08:05 < eleitl> how is IPv6 deployment doing in .uy?
08:05 < eudoxia> no idea
08:07 < eleitl> 0.01%, according to Google
08:08 < eleitl> total is 1.12%, and it looks exponential so far
08:10 < eleitl> doubling time is around one year, apparently
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09:43 <@kanzure> eleitl: yes we have diybio peeps in here
09:44 <@kanzure> paperbot: http://www.media.mit.edu/molecular/HamadNature.pdf
09:44 < paperbot> no translator available, raw dump: http://diyhpl.us/~bryan/papers2/paperbot/a2fde125ece63c808e66ee539a3691a8.pdf
09:44 <@kanzure> paperbot: http://mnras.oxfordjournals.org/content/early/2013/01/08/mnras.sts378.full
09:45 < paperbot> IOError: [Errno 2] No such file or directory: '/home/bryan/public_html/papers2/paperbot/A Galactic short gamma-ray burst as cause for the 14C peak in AD 774/5.pdf' (file "/srv/ikiwiki/paperbot/modules/papers.py", line 200, in download_url)
09:45 <@kanzure> ah
09:46 < gnusha> https://secure.diyhpl.us/cgit/paperbot/commit/?id=e021c543 Bryan Bishop: make paper titles with slashes work
09:46 < gnusha> paperbot: reload papers
09:46 < paperbot> gnusha: <module 'papers' from '/srv/ikiwiki/paperbot/modules/papers.py'> (version: 2013-01-21 17:46:27)
09:46 <@kanzure> paperbot: http://mnras.oxfordjournals.org/content/early/2013/01/08/mnras.sts378.full
09:46 < paperbot> no translator available, raw dump: http://diyhpl.us/~bryan/papers2/paperbot/A%20Galactic%20short%20gamma-ray%20burst%20as%20cause%20for%20the%2014C%20peak%20in%20AD%20774_5.pdf
09:52 < eudoxia> 167 megatonnes
09:52 < eudoxia> could've been worse
09:53 < eleitl> could have been next door
09:54 < eudoxia> 'So the knights in armour were lucky, else they would be walking microwaves'
09:54 < eudoxia> oh facepunch <3
09:55 < eleitl> gamma fries atmosphere
09:55 < eudoxia> gamma fries everything
09:55 < eudoxia> another reason to live underwater
09:56 < eleitl> apropos fried: I'm off to home. See you.
09:56 <@kanzure> someone suggested living in a supervolcano lair for the obsidian casting potential
09:57 < ParahSai1in> dragonglass
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13:21 < gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=b10004a3 Bryan Bishop: diybio-seattle link
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14:01 < eudoxia> guys quick
14:01 < eudoxia> how do you call the quality of a tumor being malign or benign?
14:01 < eudoxia> the 'malignity' or just the risk?
14:02 < jrayhawk> malignancy
14:02 < eudoxia> thanks
14:03 < eudoxia> another unrelated question: what does alcor do with the bodies of the neuropreserved?
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15:23 <@kanzure> paperbot: http://www.sciencedirect.com/science/article/pii/S1048984312000811
15:23 < paperbot> no translator available, raw dump: http://diyhpl.us/~bryan/papers2/paperbot/Born%20to%20lead%3F%20A%20twin%20design%20and%20genetic%20association%20study%20of%20leadership%20role%20occupancy%20.pdf
15:24 <@kanzure> eww a space at the end of the title.
15:24 <@kanzure> this is the worst
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15:50 < nmz787> http://www.weather.com/news/neanderthal-baby-surrogate-20130121
15:52 < nmz787> paperbot: http://ieeexplore.ieee.org/xpl/login.jsp?tp=&arnumber=806324&url=http%3A%2F%2Fieeexplore.ieee.org%2Fxpls%2Fabs_all.jsp%3Farnumber%3D806324
15:52 < paperbot> http://diyhpl.us/~bryan/papers2/paperbot/49822e4f85e6d8dee243898823ce6ea7.txt
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15:57 < jrayhawk> newuser is probably working again
15:57 < jrayhawk> you might want to change /etc/mailname to something more interesting
16:06 < nmz787> kanzure: check this out http://www.freepatentsonline.com/20130005612.pdf
16:08 < nmz787> he's checking for addition on single molecules using a fluorophore on the added nucleotide, then passing the growing strand through a nanopore past a spectrometer
16:09 < nmz787> also using the fluorophore as the protectant (which disallows multiple base addition per step)
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16:14 < nmz787> "in linear syntheses based on phosphoramidite chemistry, there are many potentioal sources of sequence erreor and oligonucleotide damage that are well documented. Most notable, the removeal of the 5'protecting group usually involves an acidic treatment that can removce the base, or in the case of photolabile 5'protecting group, require UV irradiation that can damage the nucleotide."... the nucleotide may fail to incorporate, nearly all the organic an
16:15 < nmz787> wow this patent is great
16:15 < Guest62567> this is just a test
16:15 < Guest62567> http://www.annualreviews.org/doi/abs/10.1146/annurev.genet.30.1.141
16:15 < paperbot> IndexError: list index out of range (file "/srv/ikiwiki/paperbot/modules/papers.py", line 65, in download)
16:16 < Guest62567> dx.doi.org/10.1146/annurev.genet.30.1.141
16:16 < Guest62567> www.dx.doi.org/10.1146/annurev.genet.30.1.141
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16:17 < Guest62567> http://dx.doi.org/10.1146/annurev.genet.30.1.141
16:18 < Guest62567> http://informahealthcare.com/doi/abs/10.3109/03008200903349639
16:20 < Guest62567> http://www.sciencedirect.com/science/article/pii/S106573559800011X
16:21 < Guest62567> paperbot: http://www.sciencedirect.com/science/article/pii/S106573559800011X
16:21 < paperbot> no translator available, raw dump: http://diyhpl.us/~bryan/papers2/paperbot/Processing_property_structure%20interactions%20in%20a%20calcium%20aluminate-phenol%20resin%20composite.pdf
16:37 < nmz787> paperbot: ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=806324&tag=1
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17:13 < gnusha> https://secure.diyhpl.us/cgit/paperbot/commit/?id=2c3df4e2 Bryan Bishop: handle ieee xplore login.jsp urls
17:13 < gnusha> paperbot: reload papers
17:13 < paperbot> gnusha: <module 'papers' from '/srv/ikiwiki/paperbot/modules/papers.py'> (version: 2013-01-22 01:13:21)
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17:14 <@kanzure> paperbot: http://ieeexplore.ieee.org/xpl/login.jsp?tp=&arnumber=806324&url=http%3A%2F%2Fieeexplore.ieee.org%2Fxpls%2Fabs_all.jsp%3Farnumber%3D806324
17:14 < paperbot> http://diyhpl.us/~bryan/papers2/paperbot/8462b4826166058e9cb89f764fce2db5.txt
17:14 <@kanzure> well.. that sort of worked.
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17:16 <@kanzure> jrayhawk: thank you
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17:17 <@kanzure> jrayhawk: any thoughts about unbreaking the git service?
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17:18 <@kanzure> nmz787: that's one of the guys doing gen9bio.com
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17:25 <@kanzure> http://www.nature.com/news/bloggers-put-chemical-reactions-through-the-replication-mill-1.12262
17:25 <@kanzure> "The other team members include chemistry graduate student Matt Katcher from Princeton, New Jersey, and two bloggers called Organometallica and BRSM"
17:25 <@kanzure> organometallica.
17:26 <@kanzure> did not know this "The journal Organic Syntheses, for example, only publishes synthetic procedures that have been checked and verified by a member of its editorial board."
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17:26 <@kanzure> not sure why they are trotting out chemspider though, that thing is uber-proprietary
17:27 <@kanzure> there's only one post?
17:27 <@kanzure> http://blog-syn.blogspot.co.uk/2013/01/blog-syn-001-iron-sulfur-catalysis.html
17:27 <@kanzure> seems like the barriers to get into nature news have uh lessened
17:42 < Vicarious> ohai
17:46 < barriers> u rang
18:01 < nmz787> damn I missed a relevant conference http://www.chi-peptalk.com/Genes-Vectors-Clones
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18:05 < eudoxia> well kim's entry is up http://wiki.transhumani.com/index.php?title=Cryonics#Kim_Suozzi
18:05 < eudoxia> this list is depressing as shit
18:07 < nmz787> eudoxia: why is it depressing?
18:12 < eudoxia> various sorts of dead people
18:12 < eudoxia> some of them interesting dead people, like Jerry Leaf
18:13 < eudoxia> and Curtis Henderson
18:13 < eudoxia> man fuck you Ben Best and your patient experimentation
18:15 <@kanzure> https://www.noisebridge.net/wiki/Worldwide_Aaron_Swartz_Memorial_Hackathons
18:23 < nmz787> paperbot: http://www.sciencedirect.com/science/article/pii/S016777991100179X
18:23 < paperbot> no translator available, raw dump: http://diyhpl.us/~bryan/papers2/paperbot/Error%20correction%20in%20gene%20synthesis%20technology.pdf
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18:52 < nmz787> kanzure: do you know who ted myatt is?
18:53 < nmz787> oh, he's one of the diybio safety officers
18:54 < nmz787> he's trying to add me on linkedin
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22:22 < nmz787> kanzure: ever hear of iPython?
22:22 <@kanzure> i use it all the time
22:22 < nmz787> oh really?
22:22 < nmz787> it looks a lot like matlab
22:22 <@kanzure> i currently have 34 instances of ipython running
22:22 < nmz787> damn dude, share the love
22:23 < nmz787> how don't you spam about this?
22:23 < nmz787> :)
22:23 < rigel> there was another python shell that i messed with a little bit that was great
22:23 < rigel> i dont recall the name of it though
22:23 <@kanzure> before ipython i was trying out bpython
22:24 <@kanzure> but bpython has a bunch of minor bugs that accumulate into a giant disaster
22:24 < rigel> i still need to work out the details of using virtualenv
22:24 < rigel> that was probably it
22:24 < rigel> i didnt mess with it enough to see the bugs
22:24 <@kanzure> i use virtualenv-burrito to setup virtualenv on my machines
22:24 < nmz787> kanzure: have you used the webnotebook?
22:24 < rigel> though iirc there was something odd like no scrollback or something
22:24 <@kanzure> nmz787: nope.
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22:25 <@kanzure> rigel: curl -s https://raw.github.com/brainsik/virtualenv-burrito/master/virtualenv-burrito.sh | bash
22:25 <@kanzure> next: echo "source ~/.venvburrito/startup.sh" >> ~/.bashrc
22:25 < rigel> meh
22:26 <@kanzure> then you have mkvirtualenv and friends.
22:26 < rigel> i do not need to mess with programming right now
22:26 < rigel> i need to avoid failing my classes
22:26 < rigel> and then i need to avoid failing my board exams
22:27 < rigel> though i am hearing the call of programming and technical exploration more and more, in part simply because i am not constantly being evaluated on it and told "you suck pretty bad"
22:28 < nmz787> yeah i'm writing some openSpectrometer code now in python
22:28 < rigel> i have been at least 1 SD, usually 1.7, sometimes as much as 3, below the mean. on every test so far for the last year and a half.
22:28 < yashgaroth> are you pounding adderall
22:28 < rigel> i wish i had access to adderall
22:29 <@kanzure> you're in med school.. it would be hard to *not* run into adderall
22:29 < yashgaroth> how do you survive in med school without addies
22:29 < nmz787> yashgaroth: looks like by being below the mean
22:29 < yashgaroth> ask literally any of your classmates, or bluff a doctor
22:30 < nmz787> NPR was talking about Oprah's lance armstrong interview
22:30 < nmz787> and how he doped in every tour de france
22:30 < nmz787> and basically, yeah it's not a level playing field anymore for non-doped
22:30 < nmz787> if doping is taking place
22:30 < nmz787> which it obv is
22:30 <@kanzure> when i was first getting interested in medicine, i thought this guy was the coolest dude ever for doing this:
22:30 <@kanzure> http://www.pathguy.com/meltdown.txt
22:31 <@kanzure> http://www.pathguy.com/boildown.txt
22:31 <@kanzure> nmz787: lance should use his enormous fortune to convince people that doping isn't evil
22:32 <@kanzure> nmz787: also they should keep the standings for the competitors because they were all on drugs anyway, so it's not like anything would have been different.
22:32 < nmz787> i dont know any more than i've said
22:37 < rigel> i have sort of suggested to my pcp that maybe i could use some adderall
22:37 < rigel> but they deflected
22:37 < rigel> and honestly, i dont know that it would help
22:38 <@kanzure> when you try to get adderall, never mention it by name
22:38 < rigel> i get so fucking angry at how worthless this kind of teaching is
22:38 < rigel> if i were hopped up on amphetamines i might stab someone
22:38 <@kanzure> that's not how amphetamines work
22:38 < rigel> oh, trust me i know how this shit works
22:38 < rigel> "i cant focus"
22:38 < rigel> "i am so distractable"
22:38 <@kanzure> "my job is suffering"
22:40 < rigel> i know how amphetamines work
22:40 < rigel> i know that i turn into a gigantic asshole once the plasma levels drop below a particular point
22:40 <@kanzure> i wish there was more research into how amphetamines actually work on a circuit-wide level
22:40 < yashgaroth> well at least try modafinil or something; I don't want to mention nootropics or else an hour-long discussion of stackz will appear
22:40 < rigel> and i know that i have anger control issues
22:40 <@kanzure> "it modifies dopamine levels!" is such utter bullshit
22:41 <@kanzure> http://diyhpl.us/wiki/amphetamine
22:41 < rigel> i messed with adrafinil, piracetam, hydergine, etc during undergrad
22:41 < rigel> 10 years ago
22:41 < rigel> it would be hard to say that any of them did much
22:42 < rigel> i hear modafinil is supposed to be good, but its still hideously expensive innit
22:42 < yashgaroth> oh yes it is, it's only for when I feel too guilty about being lazy on weekends
22:43 < rigel> bah, antiaging-systems no longer carries modafinil
22:43 < yashgaroth> mymodafinil.net
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22:44 < yashgaroth> well if stims don't seem to work for you, it's worth a shot to try cramming on opiates
22:45 < rigel> still pretty fucking expensive
22:45 < rigel> but it used to be like 2-3x what this site sells it for
22:45 < rigel> maybe a scrip will be cheaper
22:45 < yashgaroth> sure but once you're an MD you'll be making $texas
22:45 < rigel> right, with $400k in loans to pay back
22:46 < yashgaroth> sure, just do plastic surgery for a year
22:46 < rigel> "just do plastic surgery" he/she says
22:46 < yashgaroth> he, and yes I know
22:46 <@kanzure> indeed, those "stem cell face lifts" are apparently hot.. :/
22:46 < rigel> because you certainly dont need to be certified, and do a residency in it, in order to do plastic surgery
22:46 <@kanzure> i guarantee you that nobody did a residency in stem cell face lifting
22:47 < yashgaroth> I severely doubt they even did med school for that matter
22:47 <@kanzure> hi dr. nick
22:47 < yashgaroth> ok well how about becoming a mob doctor? that's a thing
22:47 < rigel> i dont think thats particularly well paid
22:48 < yashgaroth> all the cocaine you want
22:48 < rigel> i think thats something you do because you owe the shark about 80 large
22:49 < nmz787> kanzure: hell everybody
22:49 < nmz787> holle*
22:49 < nmz787> hello*
22:49 < yashgaroth> hi*
22:49 < nmz787> yashgaroth: how did you get modafinil?
22:49 < yashgaroth> mymodafinil.net, back when they were .com
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22:50 < yashgaroth> premium quality indian generic foil sheets
22:50 < brownies> you ordered from there?
22:50 < yashgaroth> way back when, yeah
22:50 < brownies> customs was cool with it?
22:50 < yashgaroth> held up in customs for 10 days or something, but I guess so
22:50 < yashgaroth> I think nowadays they're flagging it though, so good luck
22:51 < brownies> i have no desire to engage in anything nearly that shady
22:51 < brownies> i have just seen them hawking their wares on reddit, so i was curious
22:51 < nmz787> how way is way back?
22:52 < yashgaroth> almost a year ago I think
22:53 < rigel> oy
22:53 < nmz787> whats the armo* version?
22:53 < rigel> someone i knew in undergrad used to get a whole lot of valium and codein from an outfit in spain called "libertarian solutions"
22:53 < yashgaroth> haha
22:53 < brownies> nmz787: regular mo is a racemic mixture; armo is the purified
22:53 < rigel> again, 10 years ago, statute of limitations, etc
22:54 <@kanzure> rigel: that's an amazing outfit name
22:54 < yashgaroth> there is always silkroad too
22:54 < nmz787> ahh
22:54 < brownies> obviously that is the simplified explanation and i am not your doctor/lawyer/dentist/etc
22:54 <@kanzure> "Mobular Solutions".. send cell phones through customs for mob bosses.
22:54 < rigel> it was in keeping with their predilection for purchasing little quantities of every alphabet soup psychedelic/enpathogen to come down the pike
22:54 < brownies> wikipedia has some nice explanations on this all ... though i wouldn't mind seeing some more studies on the psychopharmacology of such things
22:54 < rigel> 2ct7, 4-AcO-DiPT, MBDB, etc
22:58 < nmz787> yeah i would like to see some neural reprogramming studies undertaken with psychedelics/empathogens in rats or mice
22:58 <@kanzure> huh? there are tons of studies with psychadelics+mice..
22:58 < nmz787> i guess there are the psilocin experiments in humans happening now, NYU I think
22:58 < rigel> i signed up for the hopkins studies
22:59 < rigel> they were trying to sign people up for that stuff for smoking cessation
22:59 < rigel> it was crazy
22:59 < nmz787> there was a conference last summer on the subject near philadelphia
22:59 < rigel> i just didnt have enough spare time to go in for the sessions and debriefing etc
22:59 < rigel> it would have been hella cool
22:59 < rigel> but just too much time investment
23:00 < nmz787> i hear tijuana has ibogaine clinics
23:00 < rigel> because it was always on weekdays
23:00 < brownies> rigel: i wish they would publish their exact experimental protocol for those studies
23:01 < augur_> there are tones of studies with psychedelics and people
23:01 < augur_> oh neural reprogramming
23:02 < augur_> depends on what you mean
23:02 < brownies> really? other than the Hopkins ones, i'm not aware of anything interesting/recent
23:02 < augur_> if you mean some NLP hogwash, hah.
23:02 < nmz787> augur_: yeah pretty broad term
23:02 < brownies> i don't know what "neural reprogramming" is... i'd just be interested to see more study done on it.
23:04 < rigel> if a site is advertising on reddit then it's probably going to be throwing money down the toilet
23:04 < rigel> the fucking president gets on reddit!
23:06 <@kanzure> http://www.hoektronics.com/2013/01/05/meet-a-shenzhen-maker-mr-chen/
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23:14 <@kanzure> http://bbs.eetop.cn/
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23:22 < nmz787> damn, is it worth learning chinese at this age?
23:22 < nmz787> would that work well?
23:25 <@kanzure> nmz787: http://pinyin.info/readings/texts/moser.html
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23:49 < brownies> nmz787: ni hao, bro.
23:53 <@kanzure> http://www.szdiy.org/
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--- Log closed Tue Jan 22 00:00:37 2013