--- Log opened Sat Mar 23 00:00:36 2013
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00:21 < jrayhawk> paperbot: http://www.nature.com/nature/journal/vaop/ncurrent/full/nature11868.html?WT.ec_id=NATURE-20130307
00:21 < paperbot> http://diyhpl.us/~bryan/papers2/paperbot/Sodium%20chloride%20drives%20autoimmune%20disease%20by%20the%20induction%20of%20pathogenic%20TH17%20cells.pdf
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00:25 < jrayhawk> We
00:25 < jrayhawk> induced hypertonicity by increasing NaCl concentration by 10–40 mM
00:25 < jrayhawk> (high-salt) in the culture medium and thus mimicked concentrations
00:25 < jrayhawk> that could be found in the interstitium of animals fed a high-salt diet7.
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03:11 < kanzure> http://youtube.com/watch?v=a014uOduLoo
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06:04 < superkuh> paperbot: http://www.nature.com/nature/journal/v494/n7438/full/494404a.html
06:05 < paperbot> http://diyhpl.us/~bryan/papers2/paperbot/Nanomaterials%3A%20Solid%20carbon%2C%20springy%20and%20light.pdf
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06:05 < EnLilaSko> paperbot: http://link.springer.com/article/10.1007%2Fs00210-002-0577-3
06:05 < paperbot> error: HTTP 500 http://diyhpl.us/~bryan/papers2/paperbot/DM235%20%28sunifiram%29%3A%20a%20novel%20nootropic%20with%20potential%20as%20a%20cognitive%20enhancer.pdf
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06:06 < superkuh> paperbot: http://onlinelibrary.wiley.com/doi/10.1002/adma.201204576/pdf
06:06 < paperbot> no translator available, raw dump: http://diyhpl.us/~bryan/papers2/paperbot/3a12c61781a059c3f1e2e82de62e4a33.txt
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06:19 < EnLilaSko> paperbot: http://link.springer.com/article/10.1007%2Fs00210-003-0812-6
06:20 < paperbot> error: HTTP 500 http://diyhpl.us/~bryan/papers2/paperbot/AMPA-receptor%20activation%20is%20involved%20in%20the%20antiamnesic%20effect%20of%20DM232%20%28unifiram%29%20and%20DM235%20%28sunifiram%29.pdf
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13:39 < abetusk> what is an 'EIA reader'?
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13:55 < kanzure> context?
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14:27 < abetusk> was a machine at the reuse center for $50.  Looks like it's from the 80's.  From a company called Bio-Tek.  Had the letters 'EL 307'
14:27 < abetusk> googling gives me this: http://en.wikipedia.org/wiki/ELISA
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14:39 < gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=07356b12 Bryan Bishop: mac cowell interview
14:40 < kanzure> "los angeles biohackathon 2013" what ? when was that.
14:41 < kanzure> "The California Endowment, the California Biotechnology Foundation, Lybba, and Wondros presented Biohackathon L.A. 2013, an immersive workshop to inspire students about the health and career benefits of STEM education and the life sciences."
14:41 < kanzure> oh.. nevermind.
14:41 < kanzure> http://www.lybba.org/blog/cityhall-design-biohackathon-hexabox-bio-design/
14:41 < nmz787> kanzure: is there a youtube or google API IRC channe;?
14:42 < kanzure> there's #google but it's sorta hit-and-miss
14:49 < kanzure> also there's a strong chance that someone in #startups regularly uses youtube with oauth2 authentication, so you can try there too.
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15:08 < yashgaroth> abetusk: probably a 96-well plate reader for ELISAs, really just a camera that sees how yellow each well turns
15:09 < abetusk> yep, I figured
15:09 < abetusk> thanks
15:10 < yashgaroth> wow those EL 307s must have been like the first plate readers ever, that's some 70's tech right there
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15:12 < kanzure> http://img.auctiva.com/imgdata/3/3/4/8/8/2/webimg/600384069_tp.jpg
15:12 < yashgaroth> 1981, I was close
15:12 < kanzure> http://img.auctiva.com/imgdata/3/3/4/8/8/2/webimg/600384188_tp.jpg
15:12 < kanzure> foot switch?
15:13 < bkero> Vim clutch?
15:13 < kanzure> lab clutch
15:14 < kanzure> someone should do a teardown on these sorts of old lab devices
15:14 < kanzure> think of the hilarious software bugs you could be missing out on
15:15 < yashgaroth> it belongs in a museum! or something
15:15 < kanzure> i think there's already a lab equipment museum somewhere
15:15 < yashgaroth> every university's dumpster
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15:36 < cpopell> kanzure, got any more info about H+ closing down?
15:36 < kanzure> nope.
15:40 < brownies> H+ closed down?
15:41 < kanzure> it's possibly closing down
15:41 < kanzure> someone mentioned to me that at least a majority of the board is considering closing it down, or wants to, or is in the process of
15:41 < brownies> i see. any reason?
15:41 < kanzure> because the org sucks and is ineffective and they all hate each other?
15:42 < brownies> i guess that is a reason
15:42 < brownies> it never was clear to me what they did. i see they have a magazine.
15:42 < kanzure> they put on conferences, debate ethics amongst themselves, try to promote their own books to themselves, bought a magazine (even though print publication has been dying for decades.. what the fuck guys)
15:43 < brownies> heh
15:44 < kanzure>  when they bought the magazine it was blowing something like 10-15k/mo
15:44 < kanzure> (this was after they cancelled the print edition)
15:45 < brownies> crazy
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16:44 < jmil> kanzure: around?
16:46 < kanzure> yes
16:54 < kanzure> http://archhaskell.wordpress.com/2010/08/13/clash-haskell-to-vhdl-compiler-in-aur/
16:54 < kanzure> haskell -> vhdl thing
16:55 < kanzure> http://archhaskell.wordpress.com/package/clash
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18:27 < kanzure> does anyone know who 6027411223 is
18:34 < ParahSail1n> alcor is in phoenix
18:34 < kanzure> it is someone who knows about alcor
18:35 < ParahSail1n> that makes sense, did alcor fire anyone recently?
18:35 < kanzure> this did not seem like someone who has worked at alcor
18:35 < yashgaroth> probably ted williams' frozen head, calling from inside its dewar
18:35 < kanzure> it was someone calling because she saw my name on facebook
18:35 < kanzure> so she decided to ask me programming questions
18:36 < kanzure> "how would i make a replacement to facebook?"
18:36 < yashgaroth> haha seriously
18:36 < kanzure> i think she was trying to sound smart, but that's probably the biggest give-away that you're totally clueless about business.
18:37 < ParahSail1n> a recruiter?
18:37 < kanzure> a recruiter wouldn't voluntarily bring up alcor or transhumanism
18:37 < ParahSail1n> and would probably tell you who she was, yeah
18:38 < kanzure> plus, the number resolves to phoenix, and i really doubt a recruiter would volunteer to live in phoenix under any circumstance
18:38 < brownies> i've always thought you were quite brave for posting your cell phone number online
18:38 < brownies> well, brave, or stupid.
18:38 < kanzure> nobody calls me
18:38 < kanzure> this is the first un-prevoked phone call i've had in a few years
18:39 < kanzure> ... well, other than recruiters. but they are sneaky anyway.
18:39 < brownies> heh
18:39 < kanzure> i mean, "the first time someone i don't know has called me, who isn't a recruiter and not otherwise expected to have my phone number"
18:40 < kanzure> i think lucas called me up a few years ago after watching one of my presentations
18:40 < yashgaroth> dimoveo?
18:40 < kanzure> that's the one
18:41 < kanzure> brownies: i think the truth is just that people don't want to call anyone these days.
18:42 < brownies> then why are people always calling me =(
18:42 < kanzure> because you don't publish your phone number
18:42 < brownies> people always want to "do a call"
18:42 < kanzure> hmmmm.
18:43 < kanzure> i can't explain this.
18:45 < brownies> heh
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20:40 -!- mode/##hplusroadmap [+o kanzure] by ChanServ
20:40 -!- kanzure changed the topic of ##hplusroadmap to: biohacking, nootropics, transhumanism, open hardware | sponsored by george church and the NRA | http://gnusha.org/logs http://diyhpl.us/wiki http://groups.google.com/group/diybio | banned by the Federal Death Administration | official paperbot fan club
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20:58 < eudoxia> it should be the eleitl fan club kanzure
21:00 <@kanzure> make your case.
21:02 < eudoxia> you said this was eleitl's fan club the other day
21:02 <@kanzure> evidence accepted.
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21:06 <@kanzure> well this looks neat
21:06 <@kanzure> http://nodecopter.com/
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21:08 <@kanzure> i knew about https://github.com/substack/virus-copter but didn't know about nodecopter somehow :(
21:09 <@kanzure> seems to possibly use this hardware? http://ardrone2.parrot.com/usa/
21:10 <@kanzure> http://www.amazon.com/Parrot-AR-Drone-Quadricopter-Controlled-Android/dp/B007HZLLOK
21:13 <@kanzure> "3 elements 1000 mA/H LiPo rechargeable battery (Autonomy: 12 minutes)" what?
21:13 <@kanzure> only 12 minutes?
21:14 < yashgaroth> I wonder if you'd get an improvement by powering the motors off of hydrocarbons
21:15 <@kanzure> http://nodecopter.com/modules
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21:15 <@kanzure> "copterface: Have your drone detecting faces using node-opencv."
21:16 <@kanzure> "drone-kinect: Control AR.Drones using your body (with a Kinect)"
21:16 < ParahSail1n> yashgaroth, yeah, batteries are pretty crappy
21:16 < ParahSail1n> unfortunately for quad rotor there might not be better option
21:17 < ParahSail1n> might be very good product to sell, come to think of it
21:19 <@kanzure> i wonder if that's 12 minutes at 11 meters/sec
21:19 <@kanzure> that's 4.9 miles (7.9 km)
21:22 < ParahSail1n> non-rotary wing aircraft can get about 10x the distance on the same fuel
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21:23 < ParahSail1n> but quadrotors easier to control than thrust-pointed-backwards-with-wings-for-lift planes
21:24 < JayDugger> ParahSail1n, do you know if any tilt-rotor model aircraft exist?
21:24 < ParahSail1n> well, i guess if you made it small enough and didnt put marines on it, it wouldnt kill marines
21:25 < yashgaroth> I have multiple ospreys fly directly over me every day, it's a little unsettling
21:26 <@kanzure> http://summerofdrones.com/
21:27 <@kanzure> "The "Summer of Drones" is an epic series of up to 34 nodecopter events for over 1500 developers to take place in North America and Europe from June - September 2013."
21:27 <@kanzure> http://dronegames.co/
21:27 <@kanzure> "Compete/Hack on drones using JavaScript! On March 9th DroneGames goes to Austin to celebrate SXSW!"
21:27 <@kanzure> fuck.
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21:29 < ParahSail1n> that samara rc aircraft seems interesting
21:29 < JayDugger> That surprises me, yashgaroth. I didn't think you lived in Arlington, TX, or near Cherry Point, NC.
21:30 < yashgaroth> under the flight path of mcas miramar
21:30 < ParahSail1n> since that thing's got a glide ratio, its gonna stay in the air longer and go farther than a quadrotor
21:30 <@kanzure> a little disappointed that none of my friends told me of that event at sxsw
21:31 <@kanzure> the suggestions on dronegames.co sorta suck. "fly in a circle!" pfft.
21:31 <@kanzure> how about "draw graffiti on a wall".
21:31 <@kanzure> or "track a person by sniffing the wifi footprint"
21:33 < yashgaroth> jaydugger: it's mostly f-18s and sea stallions, but within the last 6 months there's been ospreys waiting to explode above me
21:35 < brownies> of all the things that nodejs shouldn't be used for, i feel like robotics is high on the list =/
21:35 <@kanzure> i think something that can properly respond to interrupts makes sense
21:35 <@kanzure> and something async also makes sense
21:36 < brownies> i guess that's one way to slice it
21:36 < brownies> though i imagine that approach is significantly harder to analyze and debug
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21:37 <@kanzure> i think that's what the simulator is for https://npmjs.org/package/voxel-drone
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21:38 < brownies> haha
21:39 <@kanzure> nodecopter team presentations http://www.youtube.com/watch?v=eLqX7RMpTS8
21:42 <@kanzure> oh look they even have their own ridiculous promo video http://www.youtube.com/watch?v=gucpgJEJ5b4
21:50 < JayDugger> Dammit. I need to buy a video card that supports WebGL to test that.
21:50 < BioGuy> Just wanted to let anyone who is interested know that there is now a DIYBio meetup group in the Portland area: http://www.meetup.com/DIYBio_PDX/
21:50 <@kanzure> yeah you emailed that already
21:50 <@kanzure> we don't ignore your emails.
21:51 < BioGuy> Right, but people on IRC didn't see my email...
21:53 < BioGuy> <scratches head> unless someone else made an announcement here???
21:53 <@kanzure> yeah on 2013-03-14
21:54 -!- mode/##hplusroadmap [-o kanzure] by kanzure
21:55 < BioGuy> Ahhhh... gotcha sorry 'bout that then.
21:57 < kanzure> nothing to be sorry about.. i was just relaying information.
21:57 < kanzure> i thought you would like to know that we actually talk about you or whatever
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22:13 < BioGuy> HAHA! Thanks
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22:15 < BioGuy> I'm posting a list of useful resources and when I was adding diyhpl.us I had no idea what to call it so I just labeled it as "Huge Giganto Wiki for Open Hardware, DIYBio, etc"
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22:18 < kanzure> BioGuy: that name seems appropriate to me
22:22 < BioGuy> Ha!
22:23 < BioGuy> nmz787 You around?
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22:31 < kanzure> http://www.youtube.com/watch?v=jl5v3bsMH_E
22:31 < kanzure> heh you can just telnet in. that's fun.
22:31 < kanzure> busybox not as cool.
22:33 < ParahSail1n> kanzure, who was doing liquid handler robots
22:43 < kanzure> hmmm sphericalmouse, delinquentme, max hodak, jonathan cline, etc..
22:49 < kanzure> hm they also had a js/cnc talk http://www.youtube.com/watch?v=XbXcdhYwR8I
22:51 < kanzure> blah he wrote a gcode interpreter in javascript :/
22:57 < ParahSail1n> if they have something to sell, i have a potential customer
22:59 < kanzure> hm?
22:59 < kanzure> oh i see
22:59 < kanzure> how soon do you guys need it?
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23:02 < ParahSail1n> i think by the end of the year
23:04 < ParahSail1n> well, they'll be buying whatever the industrial-medical complex oligopolist product is if they dont see a cheap alternative before they need it
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23:10 < kanzure> alright
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23:10 < ParahSail1n> if theyre serious about startuping based on that, this could be golden opportunity
23:11 < kanzure> agreed
23:11 < kanzure> how likely is the company to buy what you recommend?
23:11 < ParahSail1n> i have little to do with what goes on in the wetlab side
23:12 < kanzure> will they want a support contract?
23:12 < ParahSail1n> so theyre gonna have to put something legit together to sell to an establishment culture business
23:12 < ParahSail1n> i imagine that would be expected
23:13 < ParahSail1n> any of those guys in the bay area?
23:15 < kanzure> delinquentme, sphericalmouse, max (although max is working on other things and would be uninterested)
23:15 < ParahSail1n> delinquent does not really impress me as useful
23:16 < ParahSail1n> maybe i should hire people and do lab robot stuff myself
23:16 < kanzure> alex/tyrant.. not sure if he's in the bay area.
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23:16 < kanzure> ParahSail1n: go for it, i think you could have a lot worse of an idea
23:16 < kanzure> *lot worse of a plan
23:17 < kanzure> uh.. i mean.. the version of that statement that sounds supportive and not insulting.
23:17 < ParahSail1n> heh
23:18 < ParahSail1n> im pretty wary of the whole wetlab industry
23:18 < ParahSail1n> extremely risk averse, so they all stick with the overpriced established vendors
23:18 < kanzure> well. so far it looks like the people that actually need the equipment who bother to build the equipment they need tend to work out okay.
23:19 < kanzure> just for whatever reason, these people don't release their custom rigs as an open source project.
23:19 < kanzure> you don't need to become a vendor
23:19 < kanzure> in fact, you might not want that job anyway
23:19 < kanzure> and there may or may not be easy money in it
23:20 < ParahSail1n> how much are robots from BD, bio-rad, or whoever makes them
23:20 < kanzure> i don't have a spreadsheet on that :(
23:20 < kanzure> all i have are vague price tags from liquidation auctions and refurbished listings on ebay
23:20 < ParahSail1n> np, i was just being lazy, hoping you had had done some research in the past about that
23:21 < kanzure> btw if you do end up getting a commercial handler, make it a tecan that is compatible with jonathan cline's perl library (Robotics::Tecan) so you can at least control the software.
23:21 < BioGuy> I'm trying to find a list of proteins useful to humans - that the average person can read and understand why they are useful. Any suggestions?
23:21 < kanzure> ParahSail1n: http://www.ebay.com/sch/i.html?_trksid=p5197.m570.l1313&_nkw=tecan+liquid+&_sacat=0&_from=R40
23:21 < kanzure> BioGuy: there are some proteins listed here (next to the snps) http://diyhpl.us/wiki/genetic-modifications/
23:22 < BioGuy> Thanks!
23:22 < kanzure> under "Gene/product"
23:23 < kanzure> ParahSail1n: "Tecan Freedom EVO 2 200 8 tip w/ posid pick & place arm automated liquid handler" $50,915
23:23 < kanzure> another one of the same model going for $39,057.50
23:23 < kanzure> and another at $30,557.50
23:23 < kanzure> http://www.ebay.com/itm/TECAN-Freedom-EVO-2-200-8-Tip-w-POSid-Pick-Place-Arm-Automated-Liquid-Handler-/230804017256?pt=LH_DefaultDomain_0&hash=item35bcfdd068
23:23 < kanzure> http://www.ebay.com/itm/TECAN-Freedom-EVO-100-8-Tip-Model-2-Diti-Automated-Liquid-Handling-Handler-Robot-/230818279314?pt=LH_DefaultDomain_0&hash=item35bdd76f92
23:24 < ParahSail1n> ah yeah, eg's just gonna buy one new, assuming its less than 100k
23:24 < kanzure> well. the advantage of using one compatible with Robotics::Tecan is that you wont be quite as locked into whatever shitty vendor software comes with it.
23:26 < kanzure> if it's 50k used, i'm not sure what the new price is. 2x?
23:26 < ParahSail1n> yeah thats what i was figuring
23:28 < kanzure> please relay any pricing information you figure out if you investigate
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23:30 < ParahSail1n> yeah ill gossip with the wetlab folks
23:31 < ParahSail1n> i forget how much they leased the ion torrent proton 1 for-- i think it was about a million
23:32 < kanzure> hahah what..
23:32 < kanzure> that was the /lease/
23:34 < ParahSail1n> ion torrent and illumina never let you buy their machines
23:35 < kanzure> i suppose that makes sense. if you are going to charge whatever you want, why would you give the hardware to consumers.
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--- Log closed Sun Mar 24 00:00:36 2013