--- Log opened Tue Jul 08 00:00:58 2014
00:09 < superkuh> https://www.youtube.com/watch?v=hVJx6GrKpLU  - "Map of Internet IPv4 Address Space Growth" updated to 2014
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08:29 < kanzure> hm, gmail has been spontaneously ignoring some of my filters
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08:37 < kanzure> welp i guess i'll be seein this everywhere.. how sad. http://tholman.com/giflinks/
08:38 < kanzure> *seeing
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08:58 < dbolser> yuck
08:58 < kanzure> weep with me
08:59  * dbolser googles for a weeping gif
09:00 < kanzure> this has gone terribly wrong
09:04 < eudoxia> technology in general, or the web
09:04 < kanzure> the conversation with dbolser
09:05 < kanzure> he's still searching for a gif
09:05 < eudoxia> well that's his fault for not having an indexed and categorized reaction image folder
09:06 < kanzure> but also that he decided to go search at all, that is also terrible
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11:28 < Daeken> http://demoseen.com/promethease/ woot, promethease report on my genome is done \o/
11:28 < chris_99> Does anyone know about an IRC room for openworm, the one i've been refered to #openworm-office doesn't have anyone in
11:29 < kanzure> they don't use irc
11:29 < chris_99> ah
11:29 < kanzure> they only use google hangouts because they are dickfaces
11:29 < chris_99> :(
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11:30 < kanzure> Daeken: "probably able to digest milk" well there you goi
11:30 < kanzure> *go
11:31 < kanzure> "Reduced conversion of beta-carotene to retinol Associated with Rs7501331 and reduced BCMO1"
11:31 < kanzure> well that explains your massive head
11:31 < FourFire> "they don't use irc" probably because they're actually doing stuff
11:31 < FourFire> ;P
11:32 < kanzure> no, it's because they like to look at their fucking faces
11:32 < kanzure> hangouts is a show-your-face chatting app
11:32 < FourFire> yes, yes I've used hangouts
11:32 < kanzure> so "hangouts" is actually doing things, but irc isn't?
11:37 < kanzure> Daeken: is that your html?
11:37 < kanzure> oh, nevermind
11:37 < kanzure> very strange way of presenting the data
11:45 < kanzure> Daeken: did they also give you an assembled genome?
11:49 < Daeken> kanzure: i have the raw samples from my genome from 23andme, available at http://demoseen.com/genome.zip
11:49 < kanzure> so just the snps?
11:49 < kanzure> knome was also giving the dna fragments plus an assembled genome plus snp data
11:50 < Daeken> yeah
11:51 < kanzure> anything actionable?
11:51 < Daeken> not that i see yet
11:51 < kanzure> lactose intolerance would be an obvious one
11:51 < kanzure> but you would sort of already know that
11:52 < jrayhawk_> Nah, you can compensate for that with gut flora.
11:52 < Daeken> it's interesting that they say that i'm likely lactose tolerant; i'm not.  but it's likely due to some other cause.
11:52 < kanzure> there's another one that says you can digest it
11:53 < jrayhawk_> There's some genetic influence on muscle fiber typing that has useful implications for training.
11:54 < dpk> paperbot: http://llc.oxfordjournals.org/content/3/2/136.full.pdf+html
11:54 < paperbot> http://libgen.org/scimag/get.php?doi=10.1093%2Fllc%2F3.2.136
11:54  * dpk farts at paperbot
11:55 < kanzure> bot abuse detected
11:55 < jrayhawk_> Robots are people too!
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11:56 < jrayhawk_> gradstudentbot: how would you describe your phylogeny
11:56 < gradstudentbot> Once you go Markov, you never go Bach.
11:56 < jrayhawk_> Forsooth.
11:57 < ParahSailin> kanzure: 23andme is an illumina microarray
11:57 < kanzure> i didn't know he was using 23andme
11:57 < ParahSailin> i suppose i should say "was"
12:00 < kanzure> "The USPTO requires synthetic sequences be deposited in Genbank and receive an accession number" (when patenting a sequence)
12:01 < Daeken> yeah, this data's from 23andme
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12:12 < ParahSailin> is there currently no accessible way for people to get beadchip genotyping?
12:13 < kanzure> haven't checked
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13:17 < ParahSailin> Daeken: how long ago did you do 23andme
13:17 < Daeken> ParahSailin: a few weeks, but i've had the kit since before the fda ban on the health data, so i got the full set.
13:18 < kanzure> ah
13:18 < kanzure> so what information is 23andme doing now?
13:18 < kanzure> do they give the snps at all? just no analysis?
13:18 < Daeken> just ancestry
13:18 < ParahSailin> so someone doing this now couldnt send in their spit to anyone?
13:18 < Daeken> i think they give the snps, too
13:18 < ParahSailin> or they can?
13:18 < Daeken> ParahSailin: how do you mean?
13:19 < ParahSailin> can i send my spit to 23andme and get the genotyping panel done
13:19 < Daeken> you can get the ancestry, and possibly the raw SNPs -- not positive on that.
13:20 < ParahSailin> ah, looks like they are doing stuff again
13:21 < Daeken> man, promethease is so freaking cool
13:21 < kanzure> is it just snpedia data?
13:21 < Daeken> yeah
13:22 < Daeken> http://www.snpedia.com/index.php/Promethease
13:22 < kanzure> i remember someone named bowman talking with me about it
13:22 < kanzure> hm it's a person in beaverton
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13:50 < kanzure> http://www.umairhaque.com/2012/01/new-economics-of-music.html
14:05 < kanzure> this does not seem to be very problematic http://www.pdfernhout.net/the-problems-of-being-self-determining.html
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14:24 < kanzure> "Unless everyone is like Bryan or Paul, with the ability to read 10,000 sources in 10 hours, attention will remain the hard scarcity in an information based economy."
14:24 < kanzure> bah
14:24 < kanzure> (2008)
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14:41 < FourFire> kanzure, it's true
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17:24 < nmz787> open-spectrometer was voted 11th place on hackaday http://hackaday.com/2014/07/08/all-precincts-reporting-next-round-of-voting-is-now/
17:26 < nmz787> http://hackaday.io/project/934-EBPVD-%26-laser-sintering-of-glass
17:26 < nmz787> e-beam physical vapor deposition
17:26 < nmz787> "CRT TV turned into a electron beam physical vapor deposition device, then used to make optics for an experimental CO2 waveguide laser"
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17:28 < nmz787> "A key factor to my motivation is that I need exercise, and regular trips across town on foot and bike to dumpster dive in the best spots is a great way for me to get it. "
17:29 < nmz787> "I'm not certain that the electron beam from a CRT is sufficient to evaporate a metal at all. "
17:29 < nmz787> :(
17:30 < nmz787> "Ideally I'll get results which come much slower than those of the commercial units, which are said to be very fast. If I don't get results then I'll still use the CRT as just a Bell jar, and sputter the mirrors I need."
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17:51 < kanzure> i should do a markov bot that generates random garbage stories like that
17:52 < kanzure> "So I constructed a {{device}} from a scavenged {{device you'll never see in your lifetime, also they stopped making it 40 years ago}}, while dumpster diving in {{city.name}}"
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18:14 < cluckj> dammit FDA quit hiding smallpox in your closets
18:17 < kanzure> having problems?
18:18 < cluckj> http://www.cdc.gov/media/releases/2014/s0708-NIH.html
18:18 < cluckj> .title
18:18 < yoleaux> CDC Media Statement on Newly Discovered Smallpox Samples
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18:20 < kanzure> "Overnight PCR testing done by CDC"
18:20 < kanzure> hope someone got overtime
18:20 < cluckj> I bet the machine did
18:21 < kanzure> didn't load itself
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18:29 < kanzure> what protein is responsible for the blue butt pigmentation in mandrillus sphinx?
18:32 < kanzure> probably something about http://en.wikipedia.org/wiki/Melanocortin_receptor
18:33 < kanzure> "We sequenced 810 bp of the MC1R coding region in 23 individuals spanning the range of male plumage variation. The only variable sites we detected among L. coronata sequences were four synonymous substitutions, none of which were strictly associated with either plumage type. Similarly, comparative analyses showed that L. coronata sequences were monomorphic at the three amino acid sites hypothesized to be functionally important in other birds. ...
18:33 < kanzure> ... These results demonstrate that genes other than MC1R underlie melanic plumage polymorphism in blue-crowned manakins."
18:33 < kanzure> where MC1R is melanocortin-1 receptor
18:35 < kanzure> paperbot: http://www.oeb.harvard.edu/faculty/hoekstra/PDFs/Hubbard2010TIG.pdf
18:35 < paperbot> http://diyhpl.us/~bryan/papers2/paperbot/7ed920fba038bb1336001d7738706ecd.pdf
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19:44 < kanzure> "For examples, every log for our BSL-3's is reviewed within a few hours of modification. If a question comes up, users have 4 hours to respond to them. If they fail to do so certain containment procedures go into effect."
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21:23 < slacko206791> whats the state of the art in nootropics so far?
21:26 < kanzure> very hit/miss
21:28 < slacko206791> about 10 years ago I was on a forum and gave some guys a formula for experimenting with combinations of a number of existing drugs to arrive at something workable.
21:28 < slacko206791> they did it and it turned out to be fantastic.
21:28 < slacko206791> it inspired that movie about the guy that was buying and selling a brain drug.
21:28 < kanzure> was it imminst
21:29 < slacko206791> bastards never told me what it was
21:29 < kanzure> imminst was a forum
21:29 < slacko206791> no
21:29 < slacko206791> not them
21:29 < slacko206791> I forget which one though
21:29 < kanzure> my bad, "longecity"
21:29 < kanzure> uh
21:29 < kanzure> *ugh
21:29 < slacko206791> I only found out because one of their friends was taunting me about it.
21:30 < slacko206791> cool first I heard of lc
21:30 < kanzure> they are the coward version of immortality institute
21:30 < slacko206791> I gave up on longevity. The situation in this world is so bad I might end up having to shoot myself.
21:30 < kanzure> best do it so
21:30 < slacko206791> We will need some serious political change before I'm worried about living forever
21:31 < slacko206791> coward - meaning they dont want to experiment?
21:31 < kanzure> meaning they changed their name because they were ashamed
21:31 < slacko206791> im still not getting it. ashamed of what?
21:31 < gradstudentbot> I was sponsored by George Church. That is, until I fell through the wormhole at the far end of the lab.
21:32 < kanzure> of their name
21:32 < kanzure> immortality institute
21:32 < slacko206791> oh ok
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21:33 < slacko206791> I don't pay any attention to people. They are either stupid, cowardly, or both.
21:34 < slacko206791> I'm diabetic and I know at least one cure for it and I wanted to find a few more diabetics so we could team up and do it ourselves rather that wait twenty years and die.
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21:34 < slacko206791> I can't find anybody. They are all scared shitless of doing anything without some brainwashed psychopath in a white coat approving it.
21:34 < kanzure> sounds like an okay pla
21:34 < kanzure> *plan
21:34 < kanzure> how many do you want?
21:35 < kanzure> diabetics, i mean
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21:35 < slacko206791> I'd like 5 people. at least 2 of whom must be reasonable intelligent and able to learn a little biology that I will teach them.
21:36 < kanzure> well, you can harass cluckj
21:36 < slacko206791> I'm guessing the whole thing will run under 5 grand but would be nice to have extra on tap if we need it.
21:44 < kanzure> well?
21:44 < slacko206791> well what?
21:45 < kanzure> how are you going to spend the $5k?
21:45 < kanzure> you don't just end the story there.. gotta spin it man.
21:45 < slacko206791> nah, gave up on the idea.
21:45 < kanzure> admirable
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21:46 < slacko206791> plus its like the longevity thing. Why?  we dont have any freedom. We are free to be obedient tax paying consumer cows.
21:46 < slacko206791> thats it.
21:46 < slacko206791> who wants to live like that?
21:46 < kanzure> then how do you explain anyone doing anything?
21:46 < kanzure> *anything at all?
21:47 < slacko206791> They don't get the big picture. They are too busy eating the grass and humping each other to realise whats going on.
21:47 < slacko206791> "only stupid people are breeding" and all that
21:48 < slacko206791> You know marvin from hitchikers guide? *me*
21:48 < kanzure> how convenient, an ideology that doesn't require you to do anything
21:49 < slacko206791> Actually I have more ideology that does.
21:49 < slacko206791> "do it because its the right thing to do, not because you expect it to succeed"
21:49 < slacko206791> as espoused cryptically in the Bagavad Gita
21:50 < kanzure> what happened to "i can't do anything because i'm the only person who sees the big picture"
21:50 < nmz787> kanzure: i thought 'how many do you want' referred to 'brainwashed psychopath in a white lab coat'
21:50 < kanzure> nah, i meant diabetos
21:51 < slacko206791> kanzure, is that japanese?
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21:51 < kanzure> diabetos is just a friendly way of saying diabetics
21:51 < nmz787> it's late night tv
21:52 < nmz787> or maybe it was early-day-time tv
21:52 < slacko206791> I was asking about your name?
21:52 < kanzure> well i was 13 when i picked kanzure, it did involve some japanese dictionaries but i'm pretty sure it's not a word
21:53 < slacko206791> ok how old now?
21:53 < kanzure> that was 2003
21:53 < kanzure> figured i would pick something i could find on search engines
21:53 < nmz787> i always thought it was like he was 'cancer'... of the internet or a message board or some video game :P
21:53 < kanzure> ouch
21:53 < nmz787> or bc he liked bio so much
21:54 < kanzure> nope, just needed something i could find on the interwebs
21:54 < nmz787> and either thought cancer was awesomesauce or he hated it and wanted to make it his life's work
21:54 < slacko206791> i c
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21:55 < nmz787> 'to beat cancer, your internet handle has to sound similar'
21:55 < kanzure> to beat cancer, you must become cancer
21:55 < slacko206791> I see. do you have cancer?
21:56 < kanzure> probably, i haven't checked
21:56 < kanzure> i thought everyone had cancer
21:56 < kanzure> and the immune system is generally okay at killing it dead
21:56 < slacko206791> I think I came up with a cure for it.
21:56 < slacko206791> everyone does - amas
21:56 < kanzure> amas?
21:56 < slacko206791> you know amas?
21:56 < slacko206791> yeah its his last name
21:56 < slacko206791> google amas + cancer
21:57 < kanzure> .g amas cancer
21:57 < yoleaux> http://www.oncolabinc.com/
21:57 < kanzure> .title
21:57 < yoleaux> An Innovative Blood Test for Early Cancer Detection and Screening
21:57 < slacko206791> he invented the blood test. Turns out everyone is positive. The test just tells you how positive you are.
21:58 < gradstudentbot> Does Jesus know about dysprosium?
21:58 < slacko206791> Most people just have a few cancerous cells here and there that the immune system is constantly cleaning up
21:58 < kanzure> isn't that what i just said
21:58 < slacko206791> but sometimes the immune system is weak or blind, or the cancer is strong and fast and you 'get' cancer
21:58 < slacko206791> yes it is!
21:58 < slacko206791> I'm agreeing with you -verbose
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--- Log closed Wed Jul 09 00:00:58 2014