--- Log opened Sat Feb 07 00:00:38 2015 --- Day changed Sat Feb 07 2015 00:00 -!- AmbulatoryCortex [~Ambulator@173-31-9-188.client.mchsi.com] has quit [Read error: Connection reset by peer] 00:06 -!- delinquentme [~delinquen@74.61.157.78] has quit [Ping timeout: 252 seconds] 00:08 -!- CheckDavid [uid14990@gateway/web/irccloud.com/x-kzyrbkbkjtfcxlot] has quit [Quit: Connection closed for inactivity] 01:03 -!- sivoais [~zaki@unaffiliated/sivoais] has quit [Ping timeout: 246 seconds] 01:11 -!- Qfwfq|zzz is now known as Qfwfq 01:12 -!- sivoais [~zaki@unaffiliated/sivoais] has joined ##hplusroadmap 01:49 -!- FourFire [~FourFire@77.88.71.230] has joined ##hplusroadmap 02:24 -!- ebowden_ [~ebowden@CPE-124-187-235-143.lns2.dav.bigpond.net.au] has quit [Ping timeout: 264 seconds] 02:54 -!- lichen [~lichen@c-50-139-11-6.hsd1.or.comcast.net] has joined ##hplusroadmap 02:56 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap 03:11 -!- narwh4l [~michael@unaffiliated/thesnark] has joined ##hplusroadmap 03:22 -!- p_h_m4_2 [~zzz@94.118.128.3] has joined ##hplusroadmap 03:48 -!- justanotheruser [~Justan@unaffiliated/justanotheruser] has quit [Ping timeout: 250 seconds] 03:55 -!- CheckDavid [uid14990@gateway/web/irccloud.com/x-insrkrhxluxueuut] has joined ##hplusroadmap 03:59 -!- ebowden [~ebowden@CPE-124-187-235-143.lns2.dav.bigpond.net.au] has joined ##hplusroadmap 04:19 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Ping timeout: 256 seconds] 05:13 < andytoshi> fenn: idk what is gudkov's conjecture (my 4-manifold-studying officemate wanted it), but we did eventually find the right paper by chasing citations from paperbot's result 05:47 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap 06:14 -!- p_h_m4_2 [~zzz@94.118.128.3] has quit [Ping timeout: 264 seconds] 06:18 -!- p_h_m4_2 [~zzz@94.118.128.12] has joined ##hplusroadmap 06:32 -!- ebowden [~ebowden@CPE-124-187-235-143.lns2.dav.bigpond.net.au] has quit [Remote host closed the connection] 06:37 -!- justanotheruser [~Justan@unaffiliated/justanotheruser] has joined ##hplusroadmap 06:38 -!- glutton [~glutton@104.131.190.121] has left ##hplusroadmap [] 06:44 -!- ebowden [~ebowden@CPE-124-187-235-143.lns2.dav.bigpond.net.au] has joined ##hplusroadmap 06:45 -!- Netsplit *.net <-> *.split quits: maaku_, andytoshi 06:45 < kanzure> hmm 06:45 -!- andytoshi [~andytoshi@wpsoftware.net] has joined ##hplusroadmap 06:46 -!- maaku [~quassel@50-0-37-37.dsl.static.fusionbroadband.com] has joined ##hplusroadmap 06:46 -!- maaku is now known as Guest63542 06:54 -!- ebowden [~ebowden@CPE-124-187-235-143.lns2.dav.bigpond.net.au] has quit [Remote host closed the connection] 07:00 -!- p_h_m4_2 [~zzz@94.118.128.12] has quit [Remote host closed the connection] 07:18 -!- FourFire [~FourFire@77.88.71.230] has quit [Ping timeout: 245 seconds] 07:38 -!- FourFire [~FourFire@77.88.71.230] has joined ##hplusroadmap 07:41 -!- narwh4l [~michael@unaffiliated/thesnark] has quit [Remote host closed the connection] 07:41 -!- dustinm [~dustinm@2607:5300:100:200::160d] has quit [Quit: Leaving] 07:43 -!- dustinm [~dustinm@105.ip-167-114-152.net] has joined ##hplusroadmap 07:46 -!- Guest63542 is now known as maaku 07:50 -!- Viper168_ [~Viper@unaffiliated/viper168] has joined ##hplusroadmap 07:50 -!- dustinm [~dustinm@105.ip-167-114-152.net] has quit [Ping timeout: 245 seconds] 07:52 -!- Viper168 [~Viper@unaffiliated/viper168] has quit [Ping timeout: 265 seconds] 07:56 -!- Zinglon [~Zinglon@ip565f6f48.direct-adsl.nl] has joined ##hplusroadmap 07:57 -!- Viper168_ is now known as Viper168 08:00 -!- abetusk [~abe@209-6-202-176.c3-0.smr-ubr2.sbo-smr.ma.cable.rcn.com] has joined ##hplusroadmap 08:02 -!- dustinm [~dustinm@2607:5300:100:200::160d] has joined ##hplusroadmap 08:33 < kanzure> .title https://www.youtube.com/watch?v=CHr1XJ-j8FE 08:33 < yoleaux> 3150 ton hydraulic forging press - YouTube 08:38 -!- FourFire [~FourFire@77.88.71.230] has quit [Ping timeout: 245 seconds] 08:42 -!- narwh4l [~michael@unaffiliated/thesnark] has joined ##hplusroadmap 09:03 -!- Merovoth [~Merovoth@gateway/tor-sasl/merovoth] has quit [Remote host closed the connection] 09:07 < kanzure> https://bettercrypto.org/static/applied-crypto-hardening.pdf 09:12 -!- narwh4l [~michael@unaffiliated/thesnark] has quit [Remote host closed the connection] 09:16 -!- delinquentme [~delinquen@74.61.157.78] has joined ##hplusroadmap 09:31 -!- PeterMeadows [~xy@131.27.187.81.in-addr.arpa] has joined ##hplusroadmap 10:03 -!- comma8 [comma8@gateway/shell/yourbnc/x-ettgyyljwjzehvgx] has quit [Read error: Connection reset by peer] 10:16 -!- erasmus [~esb@unaffiliated/erasmus] has joined ##hplusroadmap 10:22 -!- comma8 [comma8@gateway/shell/yourbnc/x-uqerigotxjfpzrel] has joined ##hplusroadmap 10:26 -!- FourFire [FourFire@2a02:270:2015:cafe:690a:2b69:7a40:4c10] has joined ##hplusroadmap 10:30 < heath> .title http://www.rsc.org/chemistryworld/2015/02/uk-government-synthetic-biology-funding-announcement 10:30 < yoleaux> UK announces £40m fund for synthetic biology | Chemistry World 10:30 < heath> .title http://www.kenilworthweeklynews.co.uk/news/local-news/warwick-university-researchers-win-12-million-to-create-new-centre-1-6562228 10:30 < yoleaux> Warwick University researchers win £12 million to create new centre - Kenilworth Weekly News 10:34 -!- erasmus [~esb@unaffiliated/erasmus] has quit [Quit: Namaste] 10:44 -!- erasmus [~esb@unaffiliated/erasmus] has joined ##hplusroadmap 10:53 -!- erasmus [~esb@unaffiliated/erasmus] has quit [Ping timeout: 244 seconds] 10:53 -!- Boscop__ [~me@e102.stw.stud.uni-saarland.de] has joined ##hplusroadmap 10:55 -!- Boscop_ [me@46.246.87.40] has quit [Ping timeout: 244 seconds] 11:00 -!- erasmus [~esb@unaffiliated/erasmus] has joined ##hplusroadmap 11:11 -!- Boscop_ [~me@178.73.223.21] has joined ##hplusroadmap 11:12 -!- Zinglon [~Zinglon@ip565f6f48.direct-adsl.nl] has quit [Ping timeout: 265 seconds] 11:13 -!- erasmus [~esb@unaffiliated/erasmus] has quit [Quit: Namaste] 11:14 -!- Boscop__ [~me@e102.stw.stud.uni-saarland.de] has quit [Ping timeout: 250 seconds] 11:27 -!- Viper168 [~Viper@unaffiliated/viper168] has quit [Ping timeout: 252 seconds] 11:34 -!- QuadIngi [~FourFire@2a02:270:2015:cafe:690a:2b69:7a40:4c10] has joined ##hplusroadmap 11:36 -!- FourFire [FourFire@2a02:270:2015:cafe:690a:2b69:7a40:4c10] has quit [Ping timeout: 252 seconds] 11:37 -!- Vutral [~ss@mirbsd/special/Vutral] has quit [Ping timeout: 250 seconds] 11:46 -!- Vutral [~ss@mirbsd/special/Vutral] has joined ##hplusroadmap 11:53 -!- PeterMeadows [~xy@131.27.187.81.in-addr.arpa] has quit [Remote host closed the connection] 12:04 -!- Merovoth [~Merovoth@gateway/tor-sasl/merovoth] has joined ##hplusroadmap 12:22 -!- ButaTine [~FourFire@77.88.71.230] has joined ##hplusroadmap 12:25 -!- QuadIngi [~FourFire@2a02:270:2015:cafe:690a:2b69:7a40:4c10] has quit [Ping timeout: 252 seconds] 12:49 -!- DumpsterD1ver [~loki@vpn166.sdf.org] has quit [Ping timeout: 245 seconds] 13:02 -!- PeterMeadows [~xy@94.118.128.7] has joined ##hplusroadmap 13:18 -!- sivoais [~zaki@unaffiliated/sivoais] has quit [Remote host closed the connection] 13:18 -!- sivoais [~zaki@unaffiliated/sivoais] has joined ##hplusroadmap 13:20 -!- eudoxia [~eudoxia@r167-56-9-0.dialup.adsl.anteldata.net.uy] has joined ##hplusroadmap 13:43 < kanzure> bloop 13:45 -!- ButaTine is now known as FourFire 13:46 < eudoxia> .wik the bloop 13:46 < yoleaux> "Bloop was an ultra-low-frequency and extremely powerful underwater sound detected by the U.S. National Oceanic and Atmospheric Administration (NOAA) in 1997. The sound was consistent with the noises generated by icequakes in large icebergs, or large icebergs scraping the ocean floor." — http://en.wikipedia.org/wiki/The_Bloop 13:46 < kanzure> it was me 14:09 -!- Zinglon [~Zinglon@ip565f6f48.direct-adsl.nl] has joined ##hplusroadmap 14:15 < kanzure> .to yashgaroth we should add "continuous dna synthesis" to the todo list... continuous operation should be possible if you can safely isolate products while synthesizing others (perhaps through mechanical tip under the surface that moves small magnetic beads out of their chambers and to flush outlets) 14:15 < yoleaux> kanzure: I'll pass your message to yashgaroth. 14:15 < kanzure> oh he is here 14:15 < kanzure> yashgaroth: hi 14:15 < yashgaroth> ah hello 14:15 < yoleaux> 22:15Z yashgaroth: we should add "continuous dna synthesis" to the todo list... continuous operation should be possible if you can safely isolate products while synthesizing others (perhaps through mechanical tip under the surface that moves small magnetic beads out of their chambers and to flush outlets) 14:16 < kanzure> fuck 14:16 < yashgaroth> sure why not 14:17 < kanzure> most machines are batch-operated 14:17 -!- delinquentme [~delinquen@74.61.157.78] has quit [Ping timeout: 244 seconds] 14:18 < kanzure> maybe there's not that much cost savings from continuous operation tho 14:18 < kanzure> if you always had things to synthesize and you were doing spatial light modulation to control sequences on an array/grid then continuous operation means you would always be synthesizing something in every spot 14:19 < yashgaroth> depends on your needs 14:19 < kanzure> "getting a workable idea that doesn't suck" 14:21 < yashgaroth> heh 14:32 -!- DumpsterD1ver [~loki@vpn166.sdf.org] has joined ##hplusroadmap 14:33 -!- delinquentme [~delinquen@74.61.157.78] has joined ##hplusroadmap 14:47 -!- Viper168 [~Viper@unaffiliated/viper168] has joined ##hplusroadmap 14:50 -!- dustinm [~dustinm@2607:5300:100:200::160d] has quit [Ping timeout: 245 seconds] 14:50 -!- comma8 [comma8@gateway/shell/yourbnc/x-uqerigotxjfpzrel] has quit [Ping timeout: 245 seconds] 14:50 -!- Vutral [~ss@mirbsd/special/Vutral] has quit [Ping timeout: 245 seconds] 14:51 -!- comma8 [comma8@gateway/shell/yourbnc/x-zslvmljogrmsjpxn] has joined ##hplusroadmap 14:51 -!- dustinm [~dustinm@105.ip-167-114-152.net] has joined ##hplusroadmap 14:58 -!- delinquentme_ [~delinquen@162-245-22-166.v250d.PUBLIC.monkeybrains.net] has joined ##hplusroadmap 14:58 -!- Vutral [~ss@mirbsd/special/Vutral] has joined ##hplusroadmap 15:00 -!- altersid_ is now known as altersid 15:02 -!- Vutral [~ss@mirbsd/special/Vutral] has quit [Excess Flood] 15:07 -!- delinquentme_ [~delinquen@162-245-22-166.v250d.PUBLIC.monkeybrains.net] has quit [Ping timeout: 244 seconds] 15:10 -!- Vutral [~ss@mirbsd/special/Vutral] has joined ##hplusroadmap 15:18 -!- FourFire [~FourFire@77.88.71.230] has quit [Ping timeout: 246 seconds] 15:48 -!- drewbot [~cinch@ec2-54-159-118-175.compute-1.amazonaws.com] has quit [Remote host closed the connection] 15:49 -!- drewbot [~cinch@ec2-54-159-192-244.compute-1.amazonaws.com] has joined ##hplusroadmap 15:49 -!- Zinglon [~Zinglon@ip565f6f48.direct-adsl.nl] has quit [Ping timeout: 265 seconds] 15:59 -!- eudoxia [~eudoxia@r167-56-9-0.dialup.adsl.anteldata.net.uy] has quit [Quit: Leaving] 16:01 -!- balrog [~balrog@discferret/developer/balrog] has quit [Ping timeout: 245 seconds] 16:10 -!- balrog [~balrog@discferret/developer/balrog] has joined ##hplusroadmap 16:28 -!- balrog [~balrog@discferret/developer/balrog] has quit [Ping timeout: 252 seconds] 16:38 -!- balrog [~balrog@discferret/developer/balrog] has joined ##hplusroadmap 16:45 -!- balrog [~balrog@discferret/developer/balrog] has quit [Remote host closed the connection] 16:48 -!- balrog [~balrog@discferret/developer/balrog] has joined ##hplusroadmap 16:53 < kanzure> .title https://news.ycombinator.com/item?id=9015570 16:53 < yoleaux> Transcriptic, a robotic cloud biology lab, is hiring scientists and engineers | Hacker News 16:56 -!- PeterMeadows [~xy@94.118.128.7] has quit [Remote host closed the connection] 17:03 -!- FourFire [~FourFire@176.75.254.106] has joined ##hplusroadmap 17:05 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Quit: Ex-Chat] 17:10 < maaku> fenn: i hope you are applying? 17:35 -!- FourFire [~FourFire@176.75.254.106] has quit [Ping timeout: 252 seconds] 17:42 -!- ebowden [~ebowden@CPE-124-187-235-143.lns2.dav.bigpond.net.au] has joined ##hplusroadmap 18:08 -!- CheckDavid [uid14990@gateway/web/irccloud.com/x-insrkrhxluxueuut] has quit [Quit: Connection closed for inactivity] 18:12 < kanzure> hehe http://www.npr.org/blogs/health/2014/04/23/305890574/dirty-money-a-microbial-jungle-thrives-in-your-wallet 18:22 -!- poohbear [~poohbear@unaffiliated/tigger] has quit [Quit: ZNC - http://znc.in] 18:23 -!- poohbear [~poohbear@unaffiliated/tigger] has joined ##hplusroadmap 18:31 -!- justanotheruser [~Justan@unaffiliated/justanotheruser] has quit [Ping timeout: 245 seconds] 18:43 -!- justanotheruser [~Justan@unaffiliated/justanotheruser] has joined ##hplusroadmap 18:55 -!- delinquentme [~delinquen@74.61.157.78] has quit [Ping timeout: 246 seconds] 18:55 -!- delinquentme [~delinquen@74.61.157.78] has joined ##hplusroadmap 19:07 < kanzure> i'm surprised by how "off" tyler's marketing is for his transcranial ultrasound company 19:07 -!- rigel [~yourmom@73.11.41.130] has joined ##hplusroadmap 19:47 -!- CheckDavid [uid14990@gateway/web/irccloud.com/x-uxmrkqmkvxdjfrxc] has joined ##hplusroadmap 19:53 -!- nameng [uid29645@gateway/web/irccloud.com/x-wwmggplhpojqdnon] has joined ##hplusroadmap 19:53 < nameng> paperbot http://www.nature.com/nphys/journal/vaop/ncurrent/full/nphys3233.html 19:53 < paperbot> http://libgen.info/scimag/get.php?doi=10.1038%2Fnphys3233 19:53 -!- ebowden [~ebowden@CPE-124-187-235-143.lns2.dav.bigpond.net.au] has quit [Remote host closed the connection] 19:54 < nameng> paperbot http://www.nature.com/nphys/journal/vaop/ncurrent/full/nphys3233.html 19:54 < paperbot> http://libgen.info/scimag/get.php?doi=10.1038%2Fnphys3233 19:55 -!- epicmeme [~TheShadow@2601:8:3e80:c:a06a:3a47:4125:6d29] has joined ##hplusroadmap 19:55 -!- epicmeme is now known as TheShadowFog 20:07 < kanzure> .title http://www.nature.com/bioent/2004/040801/full/bioent821.html 20:07 < yoleaux> What every CFO should know about equipment financing : Article : Bioentrepreneur 20:09 < kanzure> "Additionally, a request by the lender for an option to invest in future private equity rounds is a negotiable item. In the current market, typical terms would include single-digit interest rates, a 36–48-month payback period and minor warrant provisions." 20:10 < kanzure> "Because laboratory equipment used by life science companies is diverse and useful for many years, leasing is generally not a practical or cost-effective solution for such companies. Negotiating leases on many individual pieces of equipment is time-consuming and daunting and, furthermore, in the biotech industry there is little justification for having the flexibility to return leased equipment. Therefore, it is almost always in the best ... 20:10 < kanzure> ... interest of a life science company to enter into a loan agreement instead of a lease." 20:17 < nmz787> how many neurons does c elegans have, how many are i/o to sensory inputs or outputs? 20:19 < kanzure> 100ish i think 20:19 < kanzure> definitely less than 1000 neurons 20:20 < nmz787> .wa avg length and width of a neuron 20:20 < kanzure> 1031 cells, 302 neurons 20:20 < yoleaux> nmz787: Sorry, no result! 20:20 < nmz787> wondering what the most interesting microelectrode array would be dimension and pixel-size 20:21 < nmz787> 1000 i/o is do-able with an FPGA I think 20:23 < kanzure> .g marblestone boyden interfaces filetype:pdf 20:23 < yoleaux> http://web.mit.edu/amarbles/www/docs/ADAM_MARBLESTONE_CV.PDF 20:23 < kanzure> .g marblestone boyden interfaces filetype:pdf thesis 20:23 < yoleaux> http://web.mit.edu/amarbles/www/docs/ADAM_MARBLESTONE_CV.PDF 20:23 < kanzure> those fuckers 20:24 < kanzure> anyway, read his thesis 20:24 < nmz787> wow, 1200 i/o FPGA on digikey is $20k 20:24 < nmz787> 976 i/o is $8.6k 20:25 < nmz787> guess multiple smaller would be needed 20:25 < nmz787> or like 20 arduinos 20:33 < nmz787> "Optimistically, simulations of neural activity suggest that 5-10 neurons per electrode may be distinguishable using current spike sorting algorithms517,567,100. A limit of ∼10 neurons per electrode would imply N = 7.5 × 106 electrodes to record from all neurons in the mouse brain, which could be accomplished by positioning recording sites on a cubic lattice with ∼40 µm edge length." 20:39 < nmz787> "ADAS1256 resolution 16 bits Channel Count 256 price $256" 20:40 < nmz787> .title http://www.analog.com/en/press-release/11_27_12_ADI_256Channel_16Bit_Digital_XRay/press.html 20:40 < yoleaux> Analog Devices’ 256-Channel, 16-Bit Digital X-Ray Analog Front End Delivers Industry’s Best Combination of Noise, Power and Image Quality | Press Releases | Analog Devices 20:40 < nmz787> this is more reasonable, at around $80 (1 kilunits) http://www.ti.com/product/afe0256 20:40 < nmz787> .title 20:40 < yoleaux> AFE0256 | Current Input ADC | Analog to Digital Converter | Description & parametrics 21:09 -!- helleshin [~talinck@66-161-138-110.ubr1.dyn.lebanon-oh.fuse.net] has quit [Read error: Connection reset by peer] 21:09 -!- helleshin [~talinck@66-161-138-110.ubr1.dyn.lebanon-oh.fuse.net] has joined ##hplusroadmap 21:10 < kanzure> .title https://news.ycombinator.com/item?id=9015663 21:10 < yoleaux> A Xenon flash will cause the Raspberry Pi 2 to freeze | Hacker News 21:12 -!- juri_ [~juri@vpn166.sdf.org] has quit [Ping timeout: 240 seconds] 21:13 -!- juri_ [~juri@vpn166.sdf.org] has joined ##hplusroadmap 21:43 -!- TheShadowFog [~TheShadow@2601:8:3e80:c:a06a:3a47:4125:6d29] has quit [Ping timeout: 245 seconds] 22:04 -!- nameng [uid29645@gateway/web/irccloud.com/x-wwmggplhpojqdnon] has quit [Quit: Connection closed for inactivity] 22:06 -!- ebowden [~ebowden@CPE-124-187-235-143.lns2.dav.bigpond.net.au] has joined ##hplusroadmap 22:08 -!- CheckDavid [uid14990@gateway/web/irccloud.com/x-uxmrkqmkvxdjfrxc] has quit [Quit: Connection closed for inactivity] 22:18 -!- justanotheruser [~Justan@unaffiliated/justanotheruser] has quit [Ping timeout: 264 seconds] 22:24 -!- justanotheruser [~Justan@unaffiliated/justanotheruser] has joined ##hplusroadmap 22:48 -!- Viper168_ [~Viper@unaffiliated/viper168] has joined ##hplusroadmap 22:50 -!- Viper168 [~Viper@unaffiliated/viper168] has quit [Ping timeout: 265 seconds] 22:51 -!- Viper168_ is now known as Viper168 22:59 -!- lichen [~lichen@c-50-139-11-6.hsd1.or.comcast.net] has quit [Quit: Lost terminal] 23:35 -!- ebowden [~ebowden@CPE-124-187-235-143.lns2.dav.bigpond.net.au] has quit [Ping timeout: 252 seconds] 23:38 -!- delinquentme [~delinquen@74.61.157.78] has quit [Ping timeout: 256 seconds] --- Log closed Sun Feb 08 00:00:48 2015