--- Log opened Sun Mar 29 00:00:36 2015
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05:50 < kanzure> beep.
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07:11 < streety> nmz787: thanks for the pointer, I've been considering starting a project recently that the esp8266 looked good for
07:24 < archels> nmz787: are you driving Peltiers or motors?
07:24 < archels> in case of the former I can give you an efficiency report in a few weeks
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08:22 < kanzure> .title http://www.bionet.ee.columbia.edu/projects/neurokernel
08:22 < yoleaux> Neurokernel: Emulating the Fruit Fly Brain | Bionet
08:22 < kanzure> (same as the last time neurokernel was mentioned in here)
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10:14 < chris_99> noones ever seen anything about a homemade mass spectrometer out of interest?
10:23 < streety> chris_99: seen a few papers on minimal mass spec but nothing homemade as such
10:23 < streety> most of the ones I've seen weren't viable for proteomics so I didn't pay them too much attention
10:24 < chris_99> ah, cheers for the heads up, yeah i haven't seen anything from a little googling either
10:25 < streety> it would be extremely nice
10:25 < streety> thinking of working on one?
10:26 < chris_99> well i saw a 2nd hand one that would have been cool, but i don't have the space for one atm alas
10:26 < streety> they are big beasts
10:26 < chris_99> mmm
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10:30 < chris_99> check this one! - http://www.purdue.edu/uns/x/2009a/090121CooksMelamine.html
10:35 < streety> http://pubs.rsc.org/en/content/articlelanding/2010/an/b923427f#!divAbstract is their publication
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10:36 < chris_99> cheers lets see if paperbot can get it
10:36 < chris_99> paperbot: http://pubs.rsc.org/en/content/articlelanding/2010/an/b923427f#!divAbstract
10:36 < paperbot> http://diyhpl.us/~bryan/papers2/paperbot/Direct%20analysis%20of%20melamine%20in%20complex%20matrices%20using%20a%20handheld%20mass%20spectrometer.pdf
10:37 < chris_99> yay well done paperbot
10:37 < streety> I didn't realize paperbot was working again
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10:45 < nmz787> archels: got some motors and peltiers... have had some projects in mind but finding the right project to start on and finding the right drivers has been something I've been working on for a while
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10:48 < nmz787> chris_99: i've /thought/ of what a home-made mass-spec might be... but the ion/electron optics are a huge undertaking I'm pretty sure. SEMs from like 30-50 years ago couldn't get much past ~3500X magnification from what I've heard... so if the column was applied to a mass-spec I think that measn the mass-to-charge ratio would have limited resolution. That said, I was thinking a SEM or FIB column might be applicable to a hacked together ...
10:48 < nmz787> ... instrument.
10:49 < nmz787> not sure if the quadrapol/octopole would be easier to make on a MEMS scale... I've known there have been efforts for MEMS mass-spec for a few years, not sure how long those efforts have been underway in general though.
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10:53 < chris_99> that sounds interesting
10:54 < chris_99> theres more variants than i thought
10:57 < nmz787> the mass-spec is one thing... the way to get the sample in a gas-phase is another (someone mentioned proteomics, which needs a much more advanced 'atomizer'/'gasifier' (not sure the general term for this piece))
10:58 < chris_99> could you use ultrasound to create a vapour or is that not good enough for some reason
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11:02 < thundara> chris_99: Most modern mass spec instruments also nee a fair bit of electrical power / pumps to maintain the vacuum, along with liquid nitrogen to keep things cool
11:02 < thundara> Would be pretty hard to do cheaply in a diy setting
11:02 < nmz787> yeah they sell foggers for frogs and stuff at pet stores
11:02 < nmz787> thundara: newish FIB/SEM can run on 110V 15A circuits
11:02 < chris_99> i didn't realise they needed liquid nitrogen
11:03 < nmz787> I don't remember the mass-spec I used recently needing any LN2
11:03 < thundara> This is for orbitrap ones
11:04 < thundara> Depends on what you need it for though, proteomics would be pretty hard to do cheaply
11:05 < thundara> But if it's just testing 1 sample's mass, easier
11:06 < thundara> A lot of the HT proteomics stuff works with MS^2 though, which needs a gas (He / N) for ion fragmentation
11:06 < thundara> There's also ECD (electron bombardment), but I'm told that's even more expensive (in terms of instrument cost)
11:08 < thundara> I've hear word of a microfluidics device for measuring molecules' mass/charge, but I think it was more a proof-of-concept than as a fully-featured device with high sensitivity / speed / MS^n
11:11 < thundara> Oh, you linked that above >_<
11:29 < streety> when I've done mass spec proteomics in the past it was MALDI or electrospray ionisation
11:29 < streety> The apparatus didn't seem that complex
11:33 < streety> FT-ICR instruments need liquid nitrogen and helium - orbitraps seem to work similarly so it would make sense they also need cryogenic cooling
11:33 < streety> useful for discovery but if you know what you are looking for simpler instruments should be viable
11:34 < thundara> That's only part of the method though, you have sample prep -> chromatography -> ionization (ESI/MALDI) -> filtering -> fragmentation -> measurement
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11:35 < thundara> Yeah, if you have a simple sample or know what you're looking for, it's easier
11:35 < delinquentme> HOY.
11:36 < thundara> But would be hard to replicate a full proteomics setup in a diy setting
11:37 < thundara> Or at least, you'd want a different approach (Quadrupoles / TOF removes the need for cooling, iirc, unsure what is cheap / good for fragmentation though)
11:38 < t12> orbitraps dont need cooling
11:38 < streety> the chromatography would be the most challenging part prior to the MS
11:40 < thundara> t12: Erm, yeah, you're right, N gas is for the collision gas and some other parts
11:40 < t12> fancy mass specs are
11:40 < thundara> http://planetorbitrap.com/download.php?filename=4fb4392c31382.pdf
11:40 < delinquentme> TIL orbitrap
11:40 < t12> pretty painful to keep going
11:40 < delinquentme> UGH. I love this channel
11:40 < t12> easier to deal with a core facility
11:41 < thundara> Yep
11:41 < t12> acqual quadrapoles arent TOO complicated
11:41 < t12> but way untrivial
11:42 < t12> easiest diy bet is to frakenstein up various junked mass specs
11:42 < thundara> I'm told the strict tolerances of the machine make it expensive, since having magnetic fields out of alignment gives you incorrect measurements / ions banging into walls
11:42 < t12> well you calibrate all that out
11:42 < t12> at some point mechanical becomes limiting i believe
11:43 < t12> i have a scrap quadrapole around here somewhere
11:43 < thundara> Only within some tolerance, no? Shielding / vacuum are issues too
11:44 < thundara> But maybe this is all propaganda to convince me that mass specs should cost six-seven figures >_>
11:44 < delinquentme> t12 thundara where are you guys geographically
11:44 < delinquentme> ?
11:44 < t12> https://www.dropbox.com/sc/28n3xpwjdvg93hb/AADuxPlutvSv2sLsG0_rj-r0a
11:44 < t12> theres a triple quad
11:44 < t12> in a bathtub
11:45 < t12> sf
11:45 < t12> mass specs are pretty impressively built
11:46 < t12> no single part is really THAT expensive
11:46 < t12> except maybe an orbitrap itself
11:46 < t12> or the magnet in an ft
11:46 < t12> but theres just lots of stuff
11:46 < kanzure> have you seen nmz787's spectrometer design?
11:47 < t12> neg
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11:48 < thundara> Yeah, the core device is mostly machined metal and electronics
11:48 < thundara> Neg^^
11:48 < t12> i have a junk triple quad i need to put somewhere
11:48 < t12> it might work
11:49 < t12> needs turbo/controller rework
11:49 < t12> been offline at at atmosphere for a few years though
11:49 < thundara> Lab has an old one lying around that I was planning to dissect over the summer
11:49 < streety> do you have a link kanzure?
11:50 < kanzure> https://github.com/nmz787/open-spectrometer
11:50 < streety> thanks
11:50 < delinquentme> t12 you're in sf? how don't I know you irl?
11:50 < t12> unknown
11:50 < delinquentme> core speciality?
11:51 < t12> god i dunno at this point
11:51 < delinquentme> << servers, web bits of rbotics, python talking shit
11:51 < t12> previously hpc stuff
11:51 < delinquentme> hentai
11:51 < t12> right now i do microscope/lab automation
11:51 < t12> some engineering
11:51 < streety> ah, that's a spectrophotometer, not a mass spectrometer
11:51 < t12> some machining
11:51 < delinquentme> t12 can I ask for who?
11:51 < t12> a little electronics/reverseengineering
11:51 < thundara> Automation at a company? or academic
11:51 < t12> company
11:52 < delinquentme> im currently working in battery / energy grid space ... automation + bidding
11:52 < t12> holding back name for now
11:52 < t12> ahh like
11:52 < delinquentme> t12 you wanna come hangout?
11:52 < t12> that weird ca energy storage mandate thing
11:52 < delinquentme> smoke some crack ?
11:52 < t12> lol
11:52 < delinquentme> chill out ?
11:52 < delinquentme> cool!
11:52 < delinquentme> t12 if you do the FB thing
11:52 < t12> ya sure sometime
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11:53 < delinquentme> hmm im not on native irc client ...
11:53 < delinquentme> https://www.facebook.com/delinquentme
11:53 < delinquentme> there we go
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11:53 < t12> https://www.youtube.com/watch?v=0_x73hpl6io&t=25
11:54 < delinquentme> yeah add me up if you want.
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11:55 < kanzure> .title
11:55 < yoleaux> Wolf of Wall St - Smoking Crack - YouTube
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11:56 < thundara> t12: I'm curious if you could ECD cheaply for the fragmentation step
11:56 < thundara> Since it's expensive on for-sale instruments, but could just be a patent thing
11:57 < thundara> Unsure about upkeep / eletricity costs for ECD
11:57 < t12> i've seen installs of some custom ones
11:58 < t12> i dont think its that bad, its more a matter of having the rest of the stuff to install it in
11:58 < delinquentme> ha! can I like things over IRC? not yet hahaha
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11:59 < thundara> Ah, yeah, I see "electrons" and think "those are cheap!", but I don't really know what actually goes into the method
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12:53 < nmz787> haha, quadrapole in a bathtub
12:54  * nmz787 imagines the white-rabbit scene of fear and loathing except with a quadrupole instead of a radio
12:55 < chris_99> haha
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13:04 < chris_99> i'm just looking at http://en.wikipedia.org/wiki/Coulter_counter again, could you possible just use a microfluidic slide to do it
13:06 < nmz787> yep
13:06 < nmz787> using those integrated spectrum analyzer chips
13:07 < nmz787> this or one of it's similar variants (found on ebay in modules, but can have cheap non-working crystals sometimes) http://www.analog.com/en/digital-to-analog-converters/direct-digital-synthesis-dds/ad5933/products/product.html
13:07 < nmz787> we got someone in here who was working on them
13:07 < nmz787> i can't remember their name
13:07 < chris_99> i'm confused, how does a spec analyser relate to this? or is that a response to something else
13:08 < nmz787> http://gnusha.org/logs/2014-11-21.log
13:08 < nmz787> nickjohnson: ^
13:09 < nmz787> you were there chris_99 :P
13:09 < nmz787> you get a bode plot
13:09 < nmz787> which is your 'fingerprint'
13:09 < nmz787> consider your sample an antenna
13:09 < nmz787> or a signal filter
13:09 < nmz787> you get the response/lack-thereof of it
13:11 < nmz787> and for faster detection, you don't scan all the freqs, you use one or a range that is indicative/unique enough for your target of interest
13:11 < delinquentme> kanzuragi dataframe = convert_start_time(dataframe)
13:11 < nmz787> and the common signal noises that can influence other freqs response
13:11 < delinquentme> dis. does this rewrite that object ... ?
13:12 < chris_99> i thought you just detect 'pulses' nmz787, which are created as a change in resistance
13:14 < nmz787> you could probably also do something with fourier transforms, to use only square waves with diff slew-rate as input to the sample... since square waves are composed of infinite-series of sines
13:14 < nickjohnson> That's me, but doing a bode plot is different from having a spectrum analyzer.
13:14 < nickjohnson> nmz787: Square waves only have odd harmonics. A noise source is a more common approach.
13:14 < nmz787> chris_99: yeah but impedance is resistance but across more freqs
13:14 < nmz787> resistance is impedance at 0Hz
13:15 < chris_99> ah oh yeah it's impedance
13:15 < nmz787> nickjohnson: it was just an idea that came to mind... i'm no expert, but thanks for the tip for more investigation!
13:15 < nmz787> g2g drive into town
13:15 < nickjohnson> nmz787: In theory if you feed in white noise, what you get out of the FFT is your response graph
13:22 < chris_99> nickjohnson, i see your project is funded :)
13:22 < chris_99> *product
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13:25 < streety> the millipore scepter is not much more than a disposable microfluidic chip
13:26 < streety> nice concept, I really should try to get our device up and running again
13:27 < chris_99> oh not seen that
13:27 < chris_99> so it sucks up the cells and does the coulter counting thing?
13:27 < streety> yeah
13:27 < chris_99> neat
13:28 < streety> our device doesn't suck though which is "apparently" fixed by a firmware update but we've lost the "usb2" cable that isn't like any usb cable I have
13:29 < fenn> chris_99: the closest i've seen is brian hemond's paper "Development and performance of a miniature, low cost mass spectrometer" http://dspace.mit.edu/handle/1721.1/67584 http://fennetic.net/irc/mass_spectrometer_miniature_low_cost_brian_hemond.pdf  although he doesn't provide any code or actual schematics (despite them existing in a non-public git repo here: http://web.mit.edu/bhemond/git/
13:30 < fenn> i'm guessing glass-blowing would be a main technology for the DIYer without a full machine shop
13:33 < fenn> i dunno why the hell everyone immediately assumed you would be using a low cost DIY mass spec for proteomics
13:34 < chris_99> cheers fenn
13:35 < chris_99> that seems really interesting!
13:37 < streety> I think I brought up proteomics - just wishful thinking
13:38 < nickjohnson> chris_99: Yup! :)
13:38 < fenn> one nice thing a mass spec can do is unambiguous detection of elements
13:38 < nickjohnson> chris_99: Just finished redesigning part of the input frontend to support higher counting rates. :)
13:39 < streety> what's the product?
13:39 < chris_99> whatcha mean by counting rate
13:40 < nickjohnson> streety: kickstarter.com/projects/nickjohnson/tsunami
13:40 < nickjohnson> chris_99: For frequency counting on the input
13:40 < chris_99> oh gotcha, cool
13:41 < nickjohnson> The comparator is still limited - theoretically - to 4MHz, though I'm fairly sure it goes faster
13:41 < nickjohnson> But I replaced the XOR IC with a greenpak (tiny little programmable gate array from silego) for an extra $0.08, and was able to add a 2 bit selectable divider to the frontend
13:41 < nickjohnson> So the AVR pin gets the input frequency divided by 1, 16, 256, or 4096
13:42 < chris_99> XOR IC, as in logical xor, or something else
13:43 < nickjohnson> Logical xor
13:43 < nickjohnson> The Tsunami does phase detection by XORing the input signal with the generated signal, then using an RC filter to take the average
13:45 < chris_99> dumb question, what does phase detection mean exactly
13:46 < streety> looks like an interesting project - congrats on your funding success
13:46 < nickjohnson> streety: Thanks :)
13:46 < nickjohnson> chris_99: So, you generate a signal, feed it through some stuff (say, an audio amp), and get it back
13:46 < nickjohnson> It'll be attenuated somewhat, and it'll also be delayed
13:46 < nickjohnson> The delay, as a proportion of the waveform, is the phase shift
13:47 < streety> would I be right in thinking it has some of the same use cases as the red pitaya that was on kickstarter as while back?
13:47 < chris_99> aha that makes sense
13:47 < nickjohnson> Yes, but this is cheaper, lower frequency, and easier to program.
13:47 < chris_99> you could release a high freq. one too ;)
13:48 < nickjohnson> chris_99: So, I was paying $0.42 for a dedicated single gate XOR IC. But I realised I could swap it out for a greenpak3 for $0.50, and have a little programmable logic array
13:48 < nickjohnson> chris_99: I've thought about it. I know someone who's working on something similar in fact. But then you're competing with the red pitaya.
13:48 < chris_99> ahh
13:48 < chris_99> neat, what kind of stuff can you do with that programmable chip
13:48 < chris_99> is it similar to an FPGA
13:48 < nickjohnson> Lots. It's got a bunch of lookup tables, a bunch of counters, some d-flipflops, some analog comparators
13:48 < nickjohnson> Yes, just much smaller
13:48 < nickjohnson> And one-time programmable
13:49 < chris_99> oh, it has eeprom then?
13:49 < nickjohnson> I think of them as modern versions of GALs/PALs
13:49 < nickjohnson> Yeah. All you need is the chip itself and one bypass cap.
13:49 < chris_99> that sounds really interesting
13:49 < chris_99> i'll check that out
13:49 < nickjohnson> Here's the design I put together for the Tsunami: http://i.imgur.com/L6qsitL.png
13:49 < nickjohnson> Oh, and the dev kit is $60, and comes with a bunch of samples. It's really easy to work with, too
13:49 < chris_99> oh is that the way you program it via a flow chart kind of thing?
13:50 < nickjohnson> Yeah, pretty much
13:50 < nickjohnson> One day when I have spare time, I'm going to write a VHDL compiler for it :)
13:50 < nickjohnson> The registers are extensively documented
13:50 < chris_99> heh that'd be neat
13:51 < chris_99> what pin package does it have
13:51 < nickjohnson> That's the only downside: they're tiny
13:51 < chris_99> bugger :(
13:51 < nickjohnson> 0.4mm QFNs
13:51 < chris_99> i only have a normal soldering iron
13:51 < nickjohnson> Do you have a hot air gun?
13:52 < nickjohnson> (If not, why not? They're $20 on ebay :P)
13:52 < chris_99> no i don't heh, i should buy one
13:52 < nickjohnson> You could do it with an iron, but a hot air gun would be easier
13:52 < nickjohnson> I've been thinking about putting together little dip breakouts
13:52 < chris_99> with QFN don't you need to apply pasted
13:52 < chris_99> *paste
13:52 < chris_99> and reflow?
13:52 < nickjohnson> They could be awesome for retro computing enthusiasts - emulate any <18 pin 7400 series IC.
13:52 < chris_99> heh that'd be cool
13:52 < nickjohnson> Well, it helps. But you can instead tin the pads with your regular iron, add some flux, then heat it up with the hot air.
13:53 < chris_99> ah hadn't thought of that
13:53 < chris_99> i got a qfn adapter for an ADC i got
13:53 < fenn> emulate any retro computer
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14:01 < streety> are the cheap hot air guns worth it? how good are they for SMD?
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14:02 < nickjohnson> streety: They're absolutely fine for SMD.
14:02 < nickjohnson> I use mine all the time and feel no need to upgrade, personally.
14:02 < nickjohnson> I noted with amusement that dave from eevblog uses one too :P
14:02 < chris_99> i just thought i do have one of those air guns we use for a BBQ sometimes, i dunno if i could use that though
14:03 < streety> I might buy one and some cheap chips, give it a try
14:04 < chris_99> sounds like a good plan
14:04 < streety> is it just take PCB, apply solder paste, place chip, apply heat?
14:06 < nickjohnson> chris_99: I wouldn't risk it. Temperature control is vital.
14:06 < nickjohnson> streety: Yes, though you can use regular solder and an iron, followed by flux, in place of paste
14:06 < chris_99> yeah i don't really want BBQ'd chips
14:07 < streety> are there advantages to either approach?
14:09 < nickjohnson> streety: Solder paste, IME, works best with a stencil, though you can get those nice and cheap, or with very careful dispensing.
14:10 < nickjohnson> Solder and flux is self-limiting - you can't add too much solder - but it's slower and requires more attention than using a stencil
14:10  * nickjohnson -> bed
14:10 < chris_99> i saw something really neat recently that autodispenced paste
14:10 < chris_99> night
14:10 < streety> thanks nickjohnson, sleep well
14:10 < nickjohnson> 'night
14:11 < streety> I saw on dirtypcb that they offer stencils as an option, now I know why
14:11 < chris_99> https://www.kickstarter.com/projects/voltera/voltera-your-circuit-board-prototyping-machine/description
14:12 < chris_99> (not that i could afford to spend that much, but pretty cool)
14:14 < streety> there was another one I saw at the maker faire in New York last year, pick and place together with applying solder paste
14:14 < streety> again, not cheap
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14:14 < streety> would love to see one at a local makerspace though
14:15 < nickjohnson> chris_99: https://www.tindie.com/products/Pieco/paste-press/
14:15 < chris_99> yeah i've seen the guns :)
14:17 < fenn> this looks like the sort of thing one could easily make on a 3d printer
14:17 < chris_99> mmm
14:17 < chris_99> it does
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14:26 < t12> here have some troll bait
14:26 < t12> http://amormundi.blogspot.com/2012/12/is-transhumanism-racist.html
14:29 < andytoshi> whois carissa
14:29 < andytoshi> oops, i didn't mean to draw attention to quiet people
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14:35 < carissa> I am Bryan's sister, just here lurking.
14:36 < andytoshi> hi carissa. i was at lunch with bryan today, he mentioned you were here
14:36 < andytoshi> we have met before, i'm andrew, i had thanksgiving with your family
14:38 < kanzure> t12: please no
14:39 < kanzure> dae carrico is a known moron and must be avoided at all costs
14:39 < kanzure> *dale carrico
14:40 < kanzure> t12: and also i'll kickban you, so that is extra incentive to not bother us with dale carrico things
14:41 < t12> sorry was just going for entertainment!
14:41 < kanzure> that's some weird entertainment man
14:42 < kanzure> you should also avoid james hughes
14:47 < t12> you could make tumblr meme generator out of
14:47 < t12> http://upload.wikimedia.org/wikipedia/commons/thumb/c/cd/James-Hughes---rays.jpg/1024px-James-Hughes---rays.jpg
14:47 < t12> very the correct aesthetic
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14:55 < chris_99> .title https://www.youtube.com/watch?v=1gu3z7w4Vc8
14:55 < yoleaux> Festo – eMotionButterflies (English) - YouTube
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15:02 < fenn> very appropriate that the image has gratuitious noise added to it
15:04 < fenn> t12 i want to frame that photo of the mass spec core in the bath tub
15:05 < t12> i can take a better one
15:05 < fenn> tell people it's high concept art photography
15:05 < t12> though i kinda cleaned the bathtub up
15:06 < t12> i have some nice pictures of it somewhere
15:18 < t12> hum no full length ones
15:18 < t12> https://www.dropbox.com/sc/0augzr1j7q5tfhb/AACjOrQ4smQzyX8lta3qR5d3a
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15:46 < nmz787> that tri-quad-pole in a bathtub might go on a trial run as my work desktop background
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16:34 < t12> https://www.dropbox.com/s/j06rfhyi1el1r5x/20150329-20150329-_3290007.jpg?dl=0
16:34 < t12> heres a better picture
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16:36 < thundara> t12: https://lh5.googleusercontent.com/-o0OhYkHi55k/VMHvlQRqsNI/AAAAAAAABis/avWx66KVVyM/w2960-h1665-no/20150121_162914.jpg The one I want to dissect
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16:42 < t12> qstar?
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16:44 < t12> they're fun to take apart
16:44 < t12> if its destined to the trash save the stainless main chamber
16:44 < t12> they scrap out for alot
16:45 < t12> also the electronics are likely resaleable to a 3rd party repair shop
16:45 < t12> i never had luck actually doing that, but also didnt try too hard
16:48 < t12> rebuild houses will buy turbos
16:48 < t12> and the controllers
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16:56 < kiba-immle> hi
16:56 < kiba-immle> how to request a paper from the paper bot?
16:56 < kiba-immle> !request https://www.thieme-connect.com/DOI/DOI?10.1055/s-2000-9236
16:56 < kiba-immle> .request https://www.thieme-connect.com/DOI/DOI?10.1055/s-2000-9236
16:56 < kiba-immle> :-/
16:57 < kiba-immle> !paperbot https://www.thieme-connect.com/DOI/DOI?10.1055/s-2000-9236
16:58 < kiba-immle> .paperbot https://www.thieme-connect.com/DOI/DOI?10.1055/s-2000-9236
16:58 < kiba-immle> !fetch https://www.thieme-connect.com/DOI/DOI?10.1055/s-2000-9236
16:58 < kiba-immle> shiiiit
16:59 -!- kiba-immle is now known as n_bentha
17:03 < fenn> paperbot: https://www.thieme-connect.com/DOI/DOI?10.1055/s-2000-9236
17:04 < paperbot> http://diyhpl.us/~bryan/papers2/paperbot/afd2fb9d816093c8e49aaf45ef2b9d66.txt
17:04 < n_bentha> thanks fenn! it's been a while and i had forgotten >.<
17:05 < n_bentha> paperbot: https://www.thieme-connect.com/products/ejournals/html/10.1055/s-2000-9236
17:06 < paperbot> http://diyhpl.us/~bryan/papers2/paperbot/1236ceffe65c63713f1e0ec8ef68729c.txt
17:06 < fenn> paperbot: http://www.thieme-connect.com/products/ejournals/pdf/10.1055%2Fs-2000-9236.pdf
17:07 < paperbot> http://diyhpl.us/~bryan/papers2/paperbot/4153005c741d4f711f445a1a45370b09.txt
17:07 < fenn> paperbot: http://www.thieme-connect.com/products/ejournals/pdf/10.1055/s-2000-9236.pdf
17:08 < paperbot> http://diyhpl.us/~bryan/papers2/paperbot/952c5c05aa68b0065fcfa2d681bad700.txt
17:08 < fenn> i guess that's a bad url
17:09 < fenn> also paperbot can't get it, sorry
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17:11 < n_bentha> ok thanks
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17:16 < thundara> t12: Good to know, haha
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19:31 < n_bentha> paperbot: http://www.sciencemag.org/cgi/pmidlookup?view=long&pmid=19892975
19:32 < n_bentha> hey nootropics are in the discussion! awesome :D
19:32 < paperbot> http://diyhpl.us/~bryan/papers2/paperbot/Hematopoietic%20Stem%20Cell%20Gene%20Therapy%20with%20a%20Lentiviral%20Vector%20in%20X-Linked%20Adrenoleukodystrophy.pdf
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20:29 < nmz787> met this guy's son tonight http://www.mse.ncsu.edu/research/labean/
20:40 < kanzure> .title
20:40 < yoleaux> LaBean Research Group
20:40 < kanzure> "We use biopolymers"
20:41 < kanzure> looks like lot of winfree/rothemund stuff
20:42 < nmz787> paperbot: http://link.springer.com/chapter/10.1007/978-3-540-24635-0_12
20:43 < paperbot> http://diyhpl.us/~bryan/papers2/paperbot/b2f98ddd0b9c24c5a5528fe660670b32.txt
20:43 < nmz787> yeah, you recognize any of the papers?
20:44 < kanzure> not exactly, but the topics are quite similar, just more heavy metals i guess
20:48 < nmz787> http://diyhpl.us/~nmz787/pdf/Aspects_Of_Molecular_Computing.pdf
20:48 < nmz787> DNA-crypto chapter therewithin
20:52 < nmz787> one-time pads
20:52 < nmz787> hmm
20:53 < kanzure> not really one-time, you probably have millions of dna molecules floating around with the same sequence
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21:01 < nmz787> "Finally, adding ligase enzyme results in a continuous reporter strand R that runs through the entire assembly. If bi = ai ⊕ a i, for i = 1,...,n, then the reporter R = a1a2 ...an.a 1a 2 ...a n.b1b2 ...bn. The reporter strand is shown as a dotted line in Figure 3. This strand may be extracted by first melting apart the hydrogen bonding between strands and then purifying by polyacrylamide gel electrophoresis. It contains the input ...
21:01 < nmz787> ... message, the encryption key, and the ciphertext all linearly concatenated. The ciphertext can be excised using a restriction endonuclease if a cleavage site is encoded between the a0 and b1 tiles. Alternatively the reporter strand could incorporate a nick at that point by using an unphosphorylated oligo between those tiles. The ciphertext could then be gel purified since its length would be half that of the remaining sequence. This may ...
21:01 < nmz787> ... then be stored in a compact form and sent to a destination."
21:04 < nmz787> Fig 4 is pretty cool
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22:03 < n_bentha> paperbot: http://onlinelibrary.wiley.com/wol1/doi/10.1111/cen.12730/full
22:04 < paperbot> http://diyhpl.us/~bryan/papers2/paperbot/d2f63091c82e303d33e97b9356f12ac3.txt
22:05 < n_bentha> paperbot: http://onlinelibrary.wiley.com/doi/10.1111/cen.12730/epdf
22:05 < paperbot> http://diyhpl.us/~bryan/papers2/paperbot/7cd38a745c8de3f2459dc73dae607a57.txt
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22:20 < nmz787> .tell chris_99 congrats man! http://hackaday.com/2015/03/29/measuring-alcohol-content-with-time-of-flight-sensors/
22:20 < yoleaux> nmz787: I'll pass your message to chris_99.
22:23 < nmz787> .tell chris_99 this seems like the best/most-constructive comment http://en.wikipedia.org/wiki/Oscillating_U-tube
22:23 < yoleaux> nmz787: I'll pass your message to chris_99.
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