--- Log opened Sun Jun 19 00:00:33 2016
00:00 -!- augur [~augur@2601:645:c000:181b:8d11:7d3b:f69e:9e36] has quit [Ping timeout: 250 seconds]
00:08 -!- augur [~augur@c-73-15-30-163.hsd1.ca.comcast.net] has joined ##hplusroadmap
00:12 -!- Bakkot [~Bakkot@c-67-188-42-46.hsd1.ca.comcast.net] has quit [Ping timeout: 244 seconds]
00:19 -!- Bakkot [~Bakkot@c-67-188-42-46.hsd1.ca.comcast.net] has joined ##hplusroadmap
00:39 -!- seanph [~seanph@116.230.44.123] has joined ##hplusroadmap
00:42 -!- augur [~augur@c-73-15-30-163.hsd1.ca.comcast.net] has quit [Remote host closed the connection]
00:43 -!- seanph [~seanph@116.230.44.123] has quit [Ping timeout: 264 seconds]
00:45 -!- Orpheon [~Orpheon@46.140.52.182] has quit [Read error: Connection reset by peer]
00:47 -!- Orpheon [~Orpheon@46.140.52.182] has joined ##hplusroadmap
01:28 -!- Orpheon [~Orpheon@46.140.52.182] has quit [Remote host closed the connection]
01:31 -!- PatrickRobotham [uid18270@gateway/web/irccloud.com/x-argijpisjzasrpdc] has quit [Quit: Connection closed for inactivity]
01:32 -!- nildicit__ [~nildicit@unaffiliated/nildicit] has joined ##hplusroadmap
01:35 -!- nildicit_ [~nildicit@unaffiliated/nildicit] has quit [Ping timeout: 252 seconds]
01:50 -!- PatrickRobotham [uid18270@gateway/web/irccloud.com/x-flxwqbhxgyltoxbz] has joined ##hplusroadmap
02:43 -!- augur [~augur@c-73-15-30-163.hsd1.ca.comcast.net] has joined ##hplusroadmap
02:47 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap
02:48 -!- augur [~augur@c-73-15-30-163.hsd1.ca.comcast.net] has quit [Ping timeout: 244 seconds]
03:11 -!- seanph [~seanph@104.207.83.35] has joined ##hplusroadmap
03:17 -!- jaboja [~jaboja@2a00:f41:30e7:ae52:de85:deff:fe55:967a] has joined ##hplusroadmap
03:17 -!- seanph [~seanph@104.207.83.35] has quit [Ping timeout: 244 seconds]
03:36 -!- drewbot [~cinch@ec2-54-221-121-180.compute-1.amazonaws.com] has quit [Remote host closed the connection]
03:36 -!- drewbot [~cinch@ec2-107-22-93-9.compute-1.amazonaws.com] has joined ##hplusroadmap
03:52 -!- jaboja [~jaboja@2a00:f41:30e7:ae52:de85:deff:fe55:967a] has quit [Ping timeout: 264 seconds]
03:55 -!- Gurkenglas [~Gurkengla@dslb-178-005-223-183.178.005.pools.vodafone-ip.de] has joined ##hplusroadmap
04:01 -!- PatrickRobotham [uid18270@gateway/web/irccloud.com/x-flxwqbhxgyltoxbz] has quit [Quit: Connection closed for inactivity]
04:07 -!- Orpheon [~Orpheon@46.140.52.182] has joined ##hplusroadmap
04:19 -!- Orpheon [~Orpheon@46.140.52.182] has quit [Remote host closed the connection]
04:24 -!- seanph [~seanph@116.230.44.123] has joined ##hplusroadmap
04:28 -!- seanph_ [~seanph@191.96.49.157] has joined ##hplusroadmap
04:29 -!- seanph [~seanph@116.230.44.123] has quit [Ping timeout: 252 seconds]
04:33 -!- iaglium [~i@c-73-224-87-206.hsd1.fl.comcast.net] has quit [Ping timeout: 276 seconds]
04:46 < chris_99> https://hackaday.io/project/9205-blubeam-a-scanning-laser-microscope
04:46 < yoleaux> 18 Jun 2016 06:11Z <nmz787> chris_99: 3d-printer with magnetometer to map magentics http://hackaday.com/2016/06/17/hackaday-prize-entry-visualizing-magnetic-fields/
04:46 < chris_99> nmz787, saw that, thought it looked interesting!
04:54 < chris_99> anyone an idea what the resolution limits are with confocal microscopy
05:42 -!- Gurkenglas [~Gurkengla@dslb-178-005-223-183.178.005.pools.vodafone-ip.de] has quit [Ping timeout: 244 seconds]
05:53 -!- CheckDavid [uid14990@gateway/web/irccloud.com/x-kjfhczjnqyyqafcn] has joined ##hplusroadmap
06:21 < JayDugger> Good morning, all you tag-eaten brains.
06:22 -!- c0rw1n- [~c0rw1n@124.213-241-81.adsl-dyn.isp.belgacom.be] has joined ##hplusroadmap
06:29 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Ping timeout: 260 seconds]
06:45 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap
06:57 -!- jaboja [~jaboja@2a00:f41:50d0:b4d3:de85:deff:fe55:967a] has joined ##hplusroadmap
07:21 < streety> chris_99: https://en.wikipedia.org/wiki/Super-resolution_microscopy claims 250 nm
07:22 < chris_99> hmm, i thought it'd be better than that
07:22 < streety> I get a voxel size (not the same as resolution) of 640 nm with a 10x objective
07:22 < chris_99> wait isn't that number normal microscopy
07:22 < chris_99> actually
07:23 < chris_99> yeah i'm pretty sure that's not confocal
07:23 < streety> yeah, just reread and you're right
07:23 < chris_99> so itll definitely be below that number, but i'm not sure how much lower
07:24 < streety> https://en.wikipedia.org/wiki/Super-resolution_microscopy#4Pi getting closer
07:24 < chris_99> i assume it depends somewhat on the pinhole size
07:25 < streety> 100-150 nm?
07:25 < chris_99> hmm, i thought it'd be better than that actually
07:27 < chris_99> http://www3.mpibpc.mpg.de/groups/hell/publications/pdf/Appl._Phys._Lett._69_3644-3646.pdf mentions 50-100nm in the title, i'll keep looking
07:49 -!- nildicit__ [~nildicit@unaffiliated/nildicit] has quit [Ping timeout: 250 seconds]
07:59 -!- Aurelius_Laptop [~cpopell@c-73-129-20-70.hsd1.md.comcast.net] has joined ##hplusroadmap
08:01 -!- jaboja [~jaboja@2a00:f41:50d0:b4d3:de85:deff:fe55:967a] has quit [Ping timeout: 264 seconds]
08:14 -!- jaboja [~jaboja@2a00:f41:3078:18d3:de85:deff:fe55:967a] has joined ##hplusroadmap
08:40 -!- seanph_ [~seanph@191.96.49.157] has quit [Remote host closed the connection]
08:46 -!- seanph [~seanph@116.230.44.123] has joined ##hplusroadmap
08:47 -!- jaboja [~jaboja@2a00:f41:3078:18d3:de85:deff:fe55:967a] has quit [Ping timeout: 264 seconds]
08:52 -!- seanph [~seanph@116.230.44.123] has quit [Ping timeout: 276 seconds]
08:52 -!- seanph [~seanph@104.207.83.16] has joined ##hplusroadmap
08:55 -!- seanph [~seanph@104.207.83.16] has quit [Remote host closed the connection]
09:25 -!- c0rw1n_ [~c0rw1n@7.183-67-87.adsl-dyn.isp.belgacom.be] has joined ##hplusroadmap
09:26 -!- c0rw1n__ [~c0rw1n@7.183-67-87.adsl-dyn.isp.belgacom.be] has joined ##hplusroadmap
09:26 -!- c0rw1n- [~c0rw1n@124.213-241-81.adsl-dyn.isp.belgacom.be] has quit [Ping timeout: 244 seconds]
09:26 -!- c0rw1n__ is now known as c0rw1n-
09:26 -!- c0rw1n [~c0rw1n@124.213-241-81.adsl-dyn.isp.belgacom.be] has quit [Ping timeout: 276 seconds]
09:27 -!- c0rw1n_ [~c0rw1n@7.183-67-87.adsl-dyn.isp.belgacom.be] has quit [Read error: Connection reset by peer]
09:27 -!- c0rw1n- [~c0rw1n@7.183-67-87.adsl-dyn.isp.belgacom.be] has quit [Read error: Connection reset by peer]
09:27 -!- c0rw1n- [~c0rw1n@154.153-67-87.adsl-dyn.isp.belgacom.be] has joined ##hplusroadmap
09:28 -!- c0rw1n [~c0rw1n@154.153-67-87.adsl-dyn.isp.belgacom.be] has joined ##hplusroadmap
09:34 -!- Gurkenglas [Gurkenglas@dslb-178-005-223-183.178.005.pools.vodafone-ip.de] has joined ##hplusroadmap
09:35 -!- jaboja [~jaboja@vps.jaboja.pl] has joined ##hplusroadmap
09:43 -!- CuriousCat [~CuriousCa@unaffiliated/wye-naught/x-8734122] has joined ##hplusroadmap
09:44 -!- Aurelius_Laptop [~cpopell@c-73-129-20-70.hsd1.md.comcast.net] has quit [Ping timeout: 260 seconds]
09:52 -!- nildicit [~nildicit@unaffiliated/nildicit] has joined ##hplusroadmap
09:52 -!- mz_o__ [~drop_shot@68.232.180.123] has quit [Ping timeout: 240 seconds]
09:58 -!- mz_o__ [~drop_shot@68.232.180.123] has joined ##hplusroadmap
10:23 -!- jaboja [~jaboja@vps.jaboja.pl] has quit [Ping timeout: 244 seconds]
10:28 < kanzure> juul: drew seems to be anti hgp-write
10:32 -!- iaglium [~i@c-73-224-87-206.hsd1.fl.comcast.net] has joined ##hplusroadmap
10:33 < nmz787> kanzure: does he want [other-organism]-write instead? ethics/moral issues???
10:33 < kanzure> dunno, i assume juul will be able to represent his views accurately, though
10:34 < nmz787> ah
10:47 -!- Aurelius_Laptop [~cpopell@c-73-129-20-70.hsd1.md.comcast.net] has joined ##hplusroadmap
10:53 < chris_99> nmz787, did you see the confocal HaD link? seems intriguing
11:04 -!- ArturShaik [~ArturShai@212.241.12.177] has quit [Ping timeout: 260 seconds]
11:12 -!- yashgaroth [~yashgarot@2602:306:35fa:d500:f5e0:f867:a11d:8d52] has joined ##hplusroadmap
11:16 -!- mz_o__ [~drop_shot@68.232.180.123] has quit [Ping timeout: 260 seconds]
11:19 -!- mz_o__ [~drop_shot@68.232.180.123] has joined ##hplusroadmap
11:30 -!- yorick_ [~yorick@oftn/oswg-member/yorick] has joined ##hplusroadmap
11:32 -!- Aurelius_Laptop [~cpopell@c-73-129-20-70.hsd1.md.comcast.net] has quit [Ping timeout: 260 seconds]
11:32 -!- yorick [~yorick@oftn/oswg-member/yorick] has quit [Ping timeout: 240 seconds]
11:41 -!- Aurelius_Laptop [~cpopell@c-73-129-20-70.hsd1.md.comcast.net] has joined ##hplusroadmap
11:45 -!- mz_o___ [~drop_shot@68.232.180.123] has joined ##hplusroadmap
11:48 -!- QuadIgni [~fourfire@81.4.122.176] has joined ##hplusroadmap
11:49 -!- vikraman_ [~vh4x0r@gentoo/developer/vikraman] has joined ##hplusroadmap
11:50 -!- Netsplit *.net <-> *.split quits: mz_o__, kaaliakahn, nnnn20430, FourFire, vikraman, Guest31006, hylleddin
11:50 -!- vikraman_ is now known as vikraman
11:50 -!- nnnn20430_ [nnnn@lightning.bouncer.ml] has joined ##hplusroadmap
11:50 -!- nnnn20430_ is now known as nnnn20430
11:56 -!- kaaliakahn [~remote_us@45.55.206.107] has joined ##hplusroadmap
11:56 < kanzure> yashgaroth: have you read recent backlog?
11:57 -!- Guest31006 [~null@unaffiliated/madars] has joined ##hplusroadmap
11:57 -!- hylleddin [~hylleddin@2604:a880:1:20::b2:d001] has joined ##hplusroadmap
11:57 < yashgaroth> regarding brain viruses?
11:58 < kanzure> yashgaroth: i had a long phone call with human genome project 2 the other day
11:58 < kanzure> yashgaroth: we can set lots of directional details
11:59 < yashgaroth> for mass dna synthesis?
11:59 < kanzure> they want to focus on external control of enzymes and polymerase if possible
11:59 < kanzure> yes
11:59 < kanzure> they are okay with doing inkjet dna synthesis stuff, but george church and others admit that their bottleneck is assembly
12:00 < yashgaroth> could get a smidge of the money and try out the nicking + polymerase octamer system
12:00 < kanzure> think bigger plz
12:00 < kanzure> but yes we should do that
12:01 < kanzure> actually we could probably do that without them anyway
12:01 < yashgaroth> always nice to use their money, but yeah...by assembly do they mean the whole 3-billion genome, or smaller subunits?
12:02 < kanzure> well their goal is human genome
12:02 < kanzure> but yeah... "large strands of dna" in general.
12:02 < kanzure> hybridization works so much better when you have 200 bp tails to match against, anyway
12:02 < yashgaroth> well it's not like we need to stick to the normal number of chromosomes
12:03 < yashgaroth> depends how human they want to keep the resulting organism
12:04 < kanzure> they are open to whatever on that front, so yes we can do unusual numbers of chromosome if necessary
12:05 < kanzure> since they are at an early stage, now is a good time for us to think about and then propose anything that might strongly influence long-term direction of their project
12:06 < yashgaroth> well there's a lot to consider, making a human copy vs trying to improve on it, keeping it modular
12:06 < kanzure> they are willing to fund expermental and theoretical things, even speculative stuff like all the weirdo polymerase ideas we have had (in fact, the project originator has spent a lot of time in the past brainstorming with me about electronically controlled polymerases)
12:07 < kanzure> well the goal is synthesize long strands of dna
12:07 < kanzure> or, assemble them in a way that does not take forever or that is not too frustrating
12:07 < kanzure> there are some human aspects to this which can be added, but the core technology around synthesis is their primary mission. they are willing to entertain ideas about synthetic human genome engineering stuff like taking out chunks of dna or inserting high-efficiency replacements for certain areas of metabolism, although again their core mission is synthesis.
12:08 < kanzure> http://diyhpl.us/~bryan/papers2/bio/The%20human%20genome%20project%20-%20write,%20hgp-write%20-%202016.pdf
12:09 < yashgaroth> well, the more junk they're willing to cut out, the easier it'll be, hell ALU repeats are like 10% of the genome already
12:09 < kanzure> imho they should use dna synthesis for making billions of inter-connecting proteins for the purpose of molecular nanotechnology (molecular lego), at which point a bunch of other fun projects become more easily possible
12:10 < kanzure> they have good reason to want to synthesize even longer stuff; no use in making a single genome when you can make a million genomes, that sort of thing...
12:11 < yashgaroth> true, cheap large synthesis is the main benefit
12:12 < yashgaroth> how much of it are they willing to just clone out of the human genome?
12:13 < kanzure> i think amost none of it. they want to do this like the synthetic yeast genome from last year.
12:14 < yashgaroth> I can respect the principle but man a lot of that stuff you can get with two primers and polymerase
12:15 < kanzure> i haven't checked but does this mean they determined that the yeast genome does not require any methylation to work as a functional yeast genome when inserted into otherwise un-nucleated yeast cells?
12:16 < yashgaroth> not sure how much yeast care about methylation as a unicellular organism, though I suppose methylation would be easy enough to incorporate in the pamidites
12:17 < kanzure> yes it's unclear to me that sstraight up dna synthesis is useful for genomes
12:18 -!- nildicit_ [~nildicit@unaffiliated/nildicit] has joined ##hplusroadmap
12:21 -!- nildicit [~nildicit@unaffiliated/nildicit] has quit [Ping timeout: 276 seconds]
12:25 < yashgaroth> you know if they're gonna try mice etc first, or is it straight to human?
12:25 < fenn> the big bold taste of synthetic human meat
12:26 < kanzure> yashgaroth: i expect that they will have many grants involved some that will be non-human... i don't know.
12:27 < kanzure> we should probably figure out a few things they should be doing with all that $250M
12:27 < kanzure> for example, metabolism optimization would be a good thing for them to try to do
12:28 < kanzure> sperm with better flagella
12:29 < kanzure> cell pores for dna uptake
12:29 < fenn> it seems like a technology project more than a biology project
12:29 < kanzure> obviously some basic disease stuff..
12:29 < fenn> unless someone figures out some magic with molecular machines
12:29 < yashgaroth> well there's a million things to tweak, hell even if you just made the organism able to take up and propagate a megavirus that carried any potential upgrades
12:29 < kanzure> well in the original human genome project there was a specific sequencing goal but also a bunch of grants for all sorts of somewhat related projects
12:30 < kanzure> re: megavirus, yea that seems difficult because you can't really guarantee that all cells are equally accessible. i guess you could because otherwise how would the cells be feeding? hrm...
12:31 -!- CuriousCat [~CuriousCa@unaffiliated/wye-naught/x-8734122] has quit [Quit: * *  *    *        *]
12:31 < yashgaroth> there's some accessibility concerns, but if it transfers cell-to-cell and has a regulatory switch to prevent reinfection, should be doable
12:32 < yashgaroth> then you pop it into the blood and the brain, wait however long for it to spread, and bam you've got v1.1
12:33 < yashgaroth> it's bad enough us regulars are gonna get left behind, I don't want v1.0s to be like "aww man I was born a year too early for the hypersleep compatibility mod"
12:34  * kanzure marks down yashgaroth for "fear of missing out"
12:34 < yashgaroth> won't somebody please think of the ultrachildren
12:35 < kanzure> in the long run, i would like to replace chunks of human biology with something more deterministic, even if it has to be specified by dna
12:35 < yashgaroth> deterministic like how
12:35 < kanzure> mechanical clockwork would be nice
12:37 < kanzure> we could have a mechanical organelle attached to the cytoskeleton, and slowly transfer more functionality from the usual environment inside of the cell into the mechanical organelle's control and function
12:38 < yashgaroth> I'm the first to admit biology sucks compared to a lot of electromechanical stuff, even at its possible best
12:38 < kanzure> i don't think that chasing aging-related biology problems is going to be productive long-term, or other healthcare issues, because biology sucks and it breaks and is poorly designed, and i'm pretty sure we can make better designs for many of its components
12:39 < fenn> biology is optimized for evolution
12:40 < fenn> if things change your fancy rationally designed humans will maybe not adapt as well as baselines
12:40 < kanzure> bah, whatever.   if that was true, it would have more sandboxes where it tests protein function and then copies good protein function across all cells in the body. instead we have to wait a few hundred generations or something stupid like that.
12:40 < kanzure> yeah i am sure that rational-design humans will have many problems, but they will be different problems with different tradeoffs
12:41 < yashgaroth> we stopped relying on evolution a long time ago, normal humans don't adapt that well anyway, except maybe over hundreds of generations
12:41 < fenn> well i can easily see designers throwing out a lot of starvation-mode adaptations in the name of performance
12:41 < kanzure> yes that's a common pattern during refactors: oh just throw everything out, what do we need it for
12:41 < yashgaroth> if they end up starving to death I don't think we'll have done a very good job with the rest of civilization
12:42 < yashgaroth> which admittedly is a valid concern
12:42 < fenn> anyway sign me up for hypersleep 2.0
12:42 < fenn> i don't know what it is but it sounds awesome
12:43 < yashgaroth> but yeah most of the phase 1 mods via IVF is like "well they can run 10x farther than the best athletes but they do consume 20 thousand calories a day, oh well"
12:43 < yashgaroth> nor do I fenn, that's why I'd like to keep their options open
12:43 < fenn> a lot of this downloadable content stuff is a double edged sword
12:43 < fenn> you can have an immune system linked to the internet to get antivirus updates daily, but then your immune system is linked to the internet...
12:44 < kanzure> i would take the internet any day, rather than "linked to your colleagues at work and school" wtf
12:45 < kanzure> i think that the rational human design stuff is going to be at first mostly for the sake of redundancy
12:46 < kanzure> er, and of course should start with non-human anyway
12:46 < fenn> speaking of which, why isn't that a thing? synthetic B-cells for specific antigens
12:46 -!- Aurelius_Laptop [~cpopell@c-73-129-20-70.hsd1.md.comcast.net] has quit [Ping timeout: 276 seconds]
12:46 < yashgaroth> well technically it is already for cancer immunotherapy
12:46 < fenn> put it in a rabbit, inject all the school kids
12:47 < fenn> thought cancer was T-cells
12:47 < yashgaroth> ah true, well same principle applies, you gotta tailor the cells to be compatible with the host
12:48 < yashgaroth> usually by pulling some out and modifying them, which costs an absurd amount
12:48 < fenn> how many permutations are there? is it the kind of thing where you could have a dozen blood types and just keep them in stock?
12:48 < kanzure> there's a few (recent?) things that convert blood types between each other
12:49 < fenn> i mean MHC type
12:49 < yashgaroth> several hundred, roughly
12:50 < fenn> can you just include all of the types?
12:50 < fenn> like this cell is type A AND type B AND type C ... type Z20
12:51 < yashgaroth> I suppose you could try heavily modding the cells to not present any antigens to the host, though that's tricky
12:53 < fenn> eh i guess several hundred is not too bad
12:54 < fenn> you only need a tiny speck of cell culture to inoculate an individual
12:56 < yashgaroth> well, (several hundred)^3 if you consider all the HLA variants, but immunology is not my specialty
12:57 < yashgaroth> making ghost cells that avoid the host immune system entirely might be more feasible, though viruses and cancer have been trying to perfect that for a long time
13:07 -!- Orpheon [~Orpheon@98.229.62.81.dynamic.wline.res.cust.swisscom.ch] has joined ##hplusroadmap
13:26 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has quit [Ping timeout: 244 seconds]
13:35 < nmz787> IMO we have a lot of variation in human phenotype/genotype already... socioeconomic status, regional variation in climate and nutrient availability... seems like we have quite an array of adaptation ability in storage. Yes this might be overhead, but insurance always is.
13:59 -!- Aurelius_Laptop [~cpopell@c-73-129-20-70.hsd1.md.comcast.net] has joined ##hplusroadmap
14:04 -!- fleshtheworld [~fleshthew@2602:306:cf0f:4c20:c814:9239:80d2:47c8] has joined ##hplusroadmap
14:04 -!- nildicit__ [~nildicit@unaffiliated/nildicit] has joined ##hplusroadmap
14:07 -!- nildicit_ [~nildicit@unaffiliated/nildicit] has quit [Ping timeout: 250 seconds]
14:10 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has joined ##hplusroadmap
14:31 -!- jaboja [~jaboja@2a00:f41:507f:4863:de85:deff:fe55:967a] has joined ##hplusroadmap
14:47 -!- nildicit__ is now known as nildicit
14:56 -!- Darius [~quassel@cpe-158-222-160-123.nyc.res.rr.com] has joined ##hplusroadmap
14:59 < chris_99> Can anyone think of a cheap mechanism to enable the rotation & positioning of a 35mm slide size diffraction grating & slit
15:23 < fenn> yes
15:26 < chris_99> what were you thinking of fenn?
15:28 < fenn> some sort of parallel kinematic planar actuator
15:28 < fenn> flexures and electromagnets
15:28 < fenn> but i dont know what you're doing so i didnt think further
15:29 < chris_99> i'm making a simple spectrometer with a slit and transmissive grating
15:30 < fenn> why do you need to move anything?
15:30 < chris_99> i need to rotate the diffraction grating wrt the sensor
15:31 < fenn> how much? 90 degrees? 1 degree?
15:33 < chris_99> the angle of incidence of the grating is around 40 deg, i dunno how much i'd need to rotate when calibrating though
15:34 < chris_99> sorry im wrong its nearer 13 degrees
15:37 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has joined ##hplusroadmap
15:44 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has quit [Read error: Connection reset by peer]
15:55 < nmz787> chris_99: speaker and DAC + driver FET?
15:55 < nmz787> (i.e. voice coils)
15:55 < nmz787> or maybe a solenoid?
15:58 < chris_99> oh sorry i wasn't clear, i just mean to manually rotate the grating for calibration, along with positioning the slit, i'm thinking maybe even something like modular hose might work with croc clips on
15:59 < nmz787> "Hypoglycemic benefit of cinnamon, tea, witch hazel, cloves, bay leaf and allspice lost by treatment with polyvinylpyrrolidone."
16:00 < nmz787> .title http://www.ncbi.nlm.nih.gov/pubmed?orig_db=pubmed&term=10725162
16:00 < yoleaux> Insulin-like biological activity of culinary and medicinal plant aqueous extracts in vitro. - PubMed - NCBI
16:02 < chris_99> http://www.tapwithus.com/ -- i'm wondering how hard that would be to learn to use
16:03 < nmz787> "The glucose oxidation enhancing bioactivity was lost from cinnamon, tea, witch hazel, cloves, bay leaf and allspice by poly(vinylpyrrolidone) (PVP) treatment, indicating that the active phytochemicals are likely to be phenolic in nature. The activity of sage, mushrooms, and brewers's yeast was not removed by PVP."
16:10 -!- seanph [~seanph@116.230.44.123] has joined ##hplusroadmap
16:15 -!- seanph [~seanph@116.230.44.123] has quit [Ping timeout: 264 seconds]
16:23 -!- Guest31006 [~null@unaffiliated/madars] has quit [Quit: reconnect]
16:26 -!- Madars [~null@unaffiliated/madars] has joined ##hplusroadmap
16:31 -!- CuriousCat [~CuriousCa@unaffiliated/wye-naught/x-8734122] has joined ##hplusroadmap
16:51 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Ping timeout: 260 seconds]
16:52 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap
16:57 < kanzure> .wik microwriter
16:57 < yoleaux> "The Microwriter is a hand-held portable word-processor with a chording keyboard. First demonstrated in 1978, it was invented by UK-based, US-born film director Cy Endfield and his partner Chris Rainey and was marketed in the early 1980s by Microwriter Ltd, of Mitcham, Surrey, UK." — https://en.wikipedia.org/wiki/Microwriter
17:00 < kanzure> odd shape for a wearable, needs more accelerometers on a glove or something https://gest.co/technology
17:00 -!- Filosofem is now known as Jawmare
17:04 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Quit: Leaving]
17:12 -!- nildicit_ [~nildicit@unaffiliated/nildicit] has joined ##hplusroadmap
17:15 -!- nildicit [~nildicit@unaffiliated/nildicit] has quit [Ping timeout: 240 seconds]
17:20 -!- Orpheon [~Orpheon@98.229.62.81.dynamic.wline.res.cust.swisscom.ch] has quit [Read error: Connection reset by peer]
17:32 -!- nildicit__ [~nildicit@unaffiliated/nildicit] has joined ##hplusroadmap
17:32 -!- nildicit__ is now known as nildicit
17:35 -!- nildicit_ [~nildicit@unaffiliated/nildicit] has quit [Ping timeout: 250 seconds]
17:35 -!- seanph [~seanph@116.230.44.123] has joined ##hplusroadmap
17:38 -!- seanph_ [~seanph@104.207.83.16] has joined ##hplusroadmap
17:39 -!- seanph [~seanph@116.230.44.123] has quit [Ping timeout: 246 seconds]
17:48 -!- Aurelius_Laptop [~cpopell@c-73-129-20-70.hsd1.md.comcast.net] has quit [Ping timeout: 240 seconds]
18:05 -!- seanph_ [~seanph@104.207.83.16] has quit []
18:07 < kanzure> https://medschool.duke.edu/sites/medschool.duke.edu/files/pictures/Mouse_Connectivity.jpg
18:07 < kanzure> http://www.neuroscience.cam.ac.uk/uploadedFiles/mcl45_php7hgneA.jpg
18:08 < kanzure> http://neuroinformatics2011.org/abstracts/identification-and-classification-of-functional-modules-in-the-brain/image_default
18:09 < kanzure> https://team.inria.fr/parietal/files/2012/08/connectivity_2014.png
18:11 -!- jaboja [~jaboja@2a00:f41:507f:4863:de85:deff:fe55:967a] has quit [Ping timeout: 264 seconds]
18:20 < kanzure> "Individual differences in verbal creative thinking are reflected in the precuneus" https://www.researchgate.net/profile/Qunlin_Chen/publication/279737018_Individual_differences_in_verbal_creative_thinking_are_reflected_in_the_precuneus/links/55a128ee08aea54aa8143e95.pdf
18:22 -!- juri__ [~juri@c-73-134-0-28.hsd1.dc.comcast.net] has joined ##hplusroadmap
18:22 < kanzure> "Reduced frontal cortex thickness and cortical volume associated with pathological narcissism" http://www.sciencedirect.com/science/article/pii/S0306452216300902
18:23 -!- juri_ [~juri@192.94.73.195] has quit [Ping timeout: 240 seconds]
18:23 < kanzure> ".. the Pathological Narcissism Inventory score, adjusting for age, sex, and total intracranial volume, was significantly negatively associated with cortical thickness and cortical volume in the right dorsolateral prefrontal cortex"
18:24 < kanzure> "the score showed significant negative associations with cortical volume in the right postcentral gyrus, left medial prefrontal cortex (MPFC), and the cortical thickness in the right inferior frontal cortex (IFG)"
18:26 -!- HEx1 [~HEx@hexwab.plus.com] has quit [Ping timeout: 260 seconds]
18:30 < kanzure> "Increased size of posterior ventral cingulate cortex is related to the working memory performance decline.[3]"
18:32 < kanzure> "Thus, we have started developing a database of anatomical connections and architectonic features of the ferret brain, the Ferret(connect)ome, www.Ferretome.org. The Ferretome database has adapted essential features of the CoCoMac methodology and legacy, such as the CoCoMac data model"
18:32 < kanzure> what an awful name
18:32 < kanzure> *ferretome?
18:32 < kanzure> ferrtome?
18:37 < kanzure> "Vertebrate brains and evolutionary connectomics: on the origins of the mammalian 'neocortex'" https://www.researchgate.net/profile/Harvey_Karten/publication/283648861_Vertebrate_brains_and_evolutionary_connectomics_On_the_origins_of_the_mammalian_'neocortex'/links/566fb1ac08aec0bb67bf17ad.pdf
18:41 -!- fleshtheworld [~fleshthew@2602:306:cf0f:4c20:c814:9239:80d2:47c8] has quit [Read error: Connection reset by peer]
18:59 < kanzure> that is a good paper.
19:10 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has joined ##hplusroadmap
19:10 -!- Gurkenglas [Gurkenglas@dslb-178-005-223-183.178.005.pools.vodafone-ip.de] has quit [Ping timeout: 260 seconds]
19:14 -!- Orpheon [~Orpheon@98.229.62.81.dynamic.wline.res.cust.swisscom.ch] has joined ##hplusroadmap
19:28 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has quit [Remote host closed the connection]
20:33 -!- augur [~augur@2601:645:c000:181b:68ef:3957:b7ac:2a6b] has joined ##hplusroadmap
20:43 -!- fleshtheworld [~fleshthew@2602:306:cf0f:4c20:c104:e9f6:7d85:40e3] has joined ##hplusroadmap
20:46 -!- HEx1 [~HEx@hexwab.plus.com] has joined ##hplusroadmap
20:56 -!- juri__ [~juri@c-73-134-0-28.hsd1.dc.comcast.net] has quit [Ping timeout: 264 seconds]
20:57 -!- juri_ [~juri@192.94.73.193] has joined ##hplusroadmap
21:03 -!- Darius [~quassel@cpe-158-222-160-123.nyc.res.rr.com] has quit [Remote host closed the connection]
21:28 -!- Alpha703 [~Alpha703@2602:306:ccd2:7919:b145:603f:c5d8:94a1] has joined ##hplusroadmap
21:40 -!- gourneau [~gourneau@173.250.197.104.bc.googleusercontent.com] has joined ##hplusroadmap
21:42 -!- CheckDavid [uid14990@gateway/web/irccloud.com/x-kjfhczjnqyyqafcn] has quit [Quit: Connection closed for inactivity]
21:54 -!- not_unoriginal [~helpcompu@2607:fb90:6c8:4b36:0:41:e1d2:1] has joined ##hplusroadmap
21:54 < not_unoriginal> anyone here know about exosphe.re
21:56 < yashgaroth> sort of
22:04 -!- augur_ [~augur@c-73-15-30-163.hsd1.ca.comcast.net] has joined ##hplusroadmap
22:05 -!- nildicit_ [~nildicit@unaffiliated/nildicit] has joined ##hplusroadmap
22:05 -!- augur [~augur@2601:645:c000:181b:68ef:3957:b7ac:2a6b] has quit [Ping timeout: 250 seconds]
22:08 -!- nildicit [~nildicit@unaffiliated/nildicit] has quit [Ping timeout: 240 seconds]
22:13 -!- nildicit [~nildicit@unaffiliated/nildicit] has joined ##hplusroadmap
22:16 -!- nildicit_ [~nildicit@unaffiliated/nildicit] has quit [Ping timeout: 244 seconds]
22:17 -!- Alpha703 [~Alpha703@2602:306:ccd2:7919:b145:603f:c5d8:94a1] has quit [Ping timeout: 250 seconds]
22:17 -!- Alpha703 [~Alpha703@2602:306:ccd2:7919:c1b9:83b2:53a4:ad1d] has joined ##hplusroadmap
22:22 -!- Alpha703 [~Alpha703@2602:306:ccd2:7919:c1b9:83b2:53a4:ad1d] has quit [Client Quit]
22:36 -!- Diablo-D3 [~diablo@exelion.net] has left ##hplusroadmap []
22:38 -!- yashgaroth [~yashgarot@2602:306:35fa:d500:f5e0:f867:a11d:8d52] has quit [Quit: Leaving]
23:15 -!- ArturShaik [~ArturShai@212.241.12.177] has joined ##hplusroadmap
23:42 -!- QuadIgni is now known as FouFire
23:42 -!- FouFire is now known as FourFire
--- Log closed Mon Jun 20 00:00:34 2016