--- Log opened Sat Jul 02 00:00:46 2016
00:25 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has quit [Remote host closed the connection]
00:52 -!- augur [~augur@2602:304:cdac:e260:549c:7b30:cf5:a9b3] has joined ##hplusroadmap
02:21 -!- PatrickRobotham [uid18270@gateway/web/irccloud.com/x-dhzqbpiocqsqsgeo] has quit [Quit: Connection closed for inactivity]
02:27 -!- augur [~augur@2602:304:cdac:e260:549c:7b30:cf5:a9b3] has quit [Remote host closed the connection]
02:27 -!- augur [~augur@2602:304:cdac:e260:549c:7b30:cf5:a9b3] has joined ##hplusroadmap
02:32 -!- augur [~augur@2602:304:cdac:e260:549c:7b30:cf5:a9b3] has quit [Ping timeout: 250 seconds]
02:40 -!- Regex [Cara@2601:1c0:8501:d159:e9f2:a272:6db6:4b1d] has joined ##hplusroadmap
02:40 -!- Regex_ [~Cara@2601:1c0:8501:d159::3928] has quit [Ping timeout: 250 seconds]
02:41 -!- Regex_ [~Cara@2601:1c0:8501:d159:e9f2:a272:6db6:4b1d] has joined ##hplusroadmap
02:43 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap
02:43 -!- c0rw1n- [~c0rw1n@91.176.99.42] has quit [Quit: Konversation terminated!]
02:44 -!- c0rw1n- [~c0rw1n@91.176.99.42] has joined ##hplusroadmap
02:44 -!- c0rw1n- [~c0rw1n@91.176.99.42] has quit [Client Quit]
02:45 -!- Regex [Cara@2601:1c0:8501:d159:e9f2:a272:6db6:4b1d] has quit [Ping timeout: 250 seconds]
02:47 -!- c0rw1n- [~c0rw1n@91.176.99.42] has joined ##hplusroadmap
03:05 -!- seanph [~seanph@174.139.49.194] has quit [Ping timeout: 272 seconds]
03:17 -!- fleshtheworld- [~fleshthew@2602:306:cf0f:4c20:9059:b260:27ad:c455] has quit [Read error: Connection reset by peer]
03:45 -!- Gurkenglas [Gurkenglas@dslb-178-005-223-183.178.005.pools.vodafone-ip.de] has joined ##hplusroadmap
03:51 -!- nildicit [~nildicit@unaffiliated/nildicit] has quit [Ping timeout: 240 seconds]
04:06 -!- Orpheon [~Orpheon@141.94.62.81.dynamic.wline.res.cust.swisscom.ch] has joined ##hplusroadmap
04:19 -!- ArturShaik [~ArturShai@37.218.160.206] has quit [Ping timeout: 244 seconds]
04:41 -!- jaboja [~jaboja@vps.jaboja.pl] has joined ##hplusroadmap
05:32 -!- jaboja [~jaboja@vps.jaboja.pl] has quit [Ping timeout: 264 seconds]
05:45 -!- ArturShaik [~ArturShai@37.218.160.206] has joined ##hplusroadmap
05:51 -!- eudoxia [~eudoxia@r186-54-165-139.dialup.adsl.anteldata.net.uy] has joined ##hplusroadmap
06:16 -!- Orpheon [~Orpheon@141.94.62.81.dynamic.wline.res.cust.swisscom.ch] has quit [Remote host closed the connection]
06:22 -!- eudoxia [~eudoxia@r186-54-165-139.dialup.adsl.anteldata.net.uy] has quit [Quit: Leaving]
07:06 -!- sh [~sh@89.101.222.213] has quit [Ping timeout: 260 seconds]
07:06 -!- sh [~sh@89.101.222.213] has joined ##hplusroadmap
07:20 -!- clone_of_saturn [~visitant@unaffiliated/clone-of-saturn/x-2509460] has joined ##hplusroadmap
07:21 -!- clone_of_saturn is now known as saturn2
07:29 -!- Burninate [~Burn@pool-108-31-204-167.washdc.fios.verizon.net] has quit [Ping timeout: 246 seconds]
07:32 -!- Orpheon [~Orpheon@141.94.62.81.dynamic.wline.res.cust.swisscom.ch] has joined ##hplusroadmap
07:52 -!- streety [streety@2a01:7e00::f03c:91ff:feae:ded6] has joined ##hplusroadmap
07:55 -!- Burninate [~Burn@pool-108-31-204-167.washdc.fios.verizon.net] has joined ##hplusroadmap
07:56 -!- nildicit [~nildicit@unaffiliated/nildicit] has joined ##hplusroadmap
08:13 -!- AmbulatoryCortex [~Ambulator@173-31-155-69.client.mchsi.com] has joined ##hplusroadmap
08:44 -!- maaku [~quassel@173-228-107-141.dsl.static.fusionbroadband.com] has quit [Ping timeout: 244 seconds]
08:44 -!- maaku [~quassel@173-228-107-141.dsl.static.fusionbroadband.com] has joined ##hplusroadmap
09:31 -!- drewbot_ [~cinch@ec2-54-162-217-106.compute-1.amazonaws.com] has quit [Remote host closed the connection]
09:31 -!- drewbot [~cinch@ec2-54-80-62-106.compute-1.amazonaws.com] has joined ##hplusroadmap
09:40 -!- Aurelius_Laptop [~cpopell@static-108-28-104-83.washdc.fios.verizon.net] has joined ##hplusroadmap
10:10 -!- ArturShaik [~ArturShai@37.218.160.206] has quit [Ping timeout: 240 seconds]
10:24 -!- ArturShaik [~ArturShai@212.97.15.84] has joined ##hplusroadmap
10:36 -!- yashgaroth [~yashgarot@2602:306:35fa:d500:f5e0:f867:a11d:8d52] has joined ##hplusroadmap
11:14 -!- Aurelius_Laptop [~cpopell@static-108-28-104-83.washdc.fios.verizon.net] has quit [Ping timeout: 272 seconds]
11:25 -!- augur [~augur@2602:304:cdac:e260:18ab:576:1052:f2dc] has joined ##hplusroadmap
11:31 -!- ArturShaik [~ArturShai@212.97.15.84] has quit [Ping timeout: 246 seconds]
11:42 -!- jaboja [~jaboja@vps.jaboja.pl] has joined ##hplusroadmap
12:06 -!- PatrickRobotham [uid18270@gateway/web/irccloud.com/x-gcngefrunzbmscgy] has joined ##hplusroadmap
12:06 -!- augur [~augur@2602:304:cdac:e260:18ab:576:1052:f2dc] has quit [Remote host closed the connection]
12:07 -!- augur [~augur@2602:304:cdac:e260:18ab:576:1052:f2dc] has joined ##hplusroadmap
12:12 -!- augur [~augur@2602:304:cdac:e260:18ab:576:1052:f2dc] has quit [Ping timeout: 250 seconds]
12:37 -!- Paul-_ [~paul@gerbil.xs4all.nl] has joined ##hplusroadmap
12:38 < Paul-_> ls
12:38 < Paul-_> scuze me
12:38 < Paul-_> hi all
12:45 < xentrac> heh
12:45 < kanzure> greets from california
12:48 < Paul-_> so.. my uni is gonna throw out some broken PCR units. I'm pretty handy with electronics so I'm hoping I can get my hands on them and get me a working one
12:49 < Paul-_> and everything to experiment with it is quite easily obtainable
12:50 < Paul-_> the only thing I'm not so sure on is where to order primers
12:50 < Paul-_> invitrogen etc only accept orders from institutes and companies
12:51 < kanzure> there are many places to order primers
12:51 < kanzure> IDT might be a good place
12:51 < kanzure> you can also just ask a professor if he can ship to your place
12:51 < Paul-_> I'm not even sure where oligos/primers fall legally, but since I'm not gonna make hypervirulent ebola I'm less concerned with that
12:52 < yashgaroth> or genscript
12:52 < kanzure> where are you? there might be someone in your area that we know.
12:52 < Paul-_> in the NL
12:52 < kanzure> that's highly inconvenient
12:52 < Paul-_> ah, why is that?
12:54 < yashgaroth> genetically modified organisms are heavily regulated in the EU
12:54 < Paul-_> yeah I know
12:54 < Paul-_> I'm not that interested in gmos
12:54 < Paul-_> I do that in the lab all day
12:55 < yashgaroth> well you'd know more about local regs then...if you're in/near amsterdam, I'd recommend dropping by the Waag society, I'm sure they can help you out
12:55 < Paul-_> I see
12:55 < Paul-_> no, I'm not sure how this is regulated
12:56 < Paul-_> I've seen crispr/cas9 kits that everyone can just order
12:56 < yashgaroth> yeah don't worry those are pretty useless
12:56 < Paul-_> I know, I used it myself once
12:56 < Paul-_> well not the kits
12:57 < Paul-_> it's a nice system but recombineering is a pain in the ass
12:57 -!- CuriousCat [~CuriousCa@2602:30a:2c94:5460:3472:a59e:2599:724d] has joined ##hplusroadmap
12:57 -!- CuriousCat [~CuriousCa@2602:30a:2c94:5460:3472:a59e:2599:724d] has quit [Changing host]
12:57 -!- CuriousCat [~CuriousCa@unaffiliated/wye-naught/x-8734122] has joined ##hplusroadmap
12:57 < yashgaroth> oh you don't have to tell me
12:58 < yashgaroth> still, pieter van boheemen is the only person I know in NL involved in DIYbio, I'm sure he'd be happy to answer any questions
12:58 < Paul-_> I suppose PCR would be the biggest enabling step if you'd want to make gmos
12:59 < yashgaroth> all I know of EU regs is that they're fairly illogical, so I can't guarantee that you or the government will really know what's allowed
12:59 < kanzure> yashgaroth: hanging out with HGP person. he wants to focus on synthetic viruses.
12:59 < Paul-_> haha fair enough
13:00 < yashgaroth> what like a series of 400,000 viruses that sequentially invade an empty nucleus to get you a full genome
13:00 < Paul-_> I thought it would be fun to try some redundant forensic dna comparison stuff
13:01 < Paul-_> sequencing isn't that hard to get done I believe, so it would also be useful for species identification
13:02 < yashgaroth> sequencing is more of a pain than the usual DNA fingerprinting, but not too painful
13:04 < kanzure> no the virus stuff is unrelated to synthesis
13:04 < kanzure> other than using synthesis to make novel viruses, that is
13:04 < kanzure> he did a 33kb virus recently for dog cancer reasons, but 33 kb the long/old way
13:07 < yashgaroth> I am now almost an expert on AAV bullshit, other viruses not so much; what's he trying to do with them aside from giving cancer to dogs
13:08 < Paul-_> yeah but if I want to know which orchid something is dna fingerprinting is useless but it's probably already barcoded
13:09 < yashgaroth> true, but then you're getting into denaturing acrylamide gels rather than delicious agarose
13:09 < Paul-_> barcoding primers I can get tho, if I ask naturalis they'll happily give me some of their 16s or folmer
13:09 < kanzure> i guess i should go to this http://2016.oshwa.org/ does anyone have suggestions for what to speak about http://2016.oshwa.org/speak/ (it's in portland, so i would have to meet jrayhawk or something)
13:10 < kanzure> yashgaroth: well he wants disposable one-shot "epi pens" for viral gene therapy including synthesis on the same device
13:10 < Paul-_> does anyone have experience with eurofins?
13:11 < yashgaroth> does the epipen include a multi-week course of immunosuppressants? I'm not even going to touch the synthesis part
13:12 < kanzure> naaaah
13:12 < kanzure> who cares about immune response pfft
13:12 < kanzure> just sell only to immuno-compromised individuals!
13:12 < kanzure> wait....
13:13 < Paul-_> I think I still have a gram of dexamethasone laying around if you want to wipe out all immune functions :p
13:14 < yashgaroth> if you're at the point where you can synthesize an entire functioning virus in some fucking tube, and not in a large biomanufacturing facility, I'm pretty sure you're dreaming anyway, in which case why not go to mars
13:17 < kanzure> he says he has been building a synthetic virus manufacturing line
13:17 < kanzure> not quite a single tube at the moment but he has the semiconductor industry working on the minituriazation for some reason
13:17 < kanzure> (autodesk)
13:19 < yashgaroth> it's a nice idea but I worry he'll spend too much time trying to fit it into a tube, and by 'too much time' I mean literally any time at all
13:20 < kanzure> it wont be him in particular
13:20 < kanzure> it's not a short-term project
13:21 < kanzure> his idea of short-term is https://groups.google.com/group/enzymaticsynthesis
13:21 < yashgaroth> oh good
13:22 < kanzure> i should pay you to do some validation work on the nicking enzyme stuff
13:22 < kanzure> has bioviva emploded yet by any chance?
13:22 < yashgaroth> it...pm
13:28 < xentrac> haha
13:28 < kanzure> imploded, sorry
13:29 < yashgaroth> that implies there was something to 'plode in the first place
13:29 < yashgaroth> oh you were just correcting your earlier statement, not confirming
13:29 < yashgaroth> cough
13:30 < xentrac> do you know Liz?
13:30 < yashgaroth> maybe
13:31 < kanzure> xentrac: we have infiltrators kinda and i think i might be investing maybe
13:31 < kanzure> and also we know their biologist
13:34 < kanzure> 23andme for dogs https://embarkvet.com/
13:36 < kanzure> nmz787: other than using flowing water to push dna into a small container to make it curl up, what are some good ways to avoid long dna breaking up under its own tension/stress? this turns out to be a problem with electronically-controlled polymerase production of dna...
13:39 < kanzure> jrayhawk: will you be going to that portland open hardware event thing?
14:14 -!- sandeepkr_ [~sandeep@111.235.64.4] has joined ##hplusroadmap
14:15 -!- Aurelius_Laptop [~cpopell@c-73-200-185-48.hsd1.va.comcast.net] has joined ##hplusroadmap
14:17 -!- sandeepkr [~sandeep@111.235.64.4] has quit [Ping timeout: 264 seconds]
14:19 -!- Aurelius_Laptop [~cpopell@c-73-200-185-48.hsd1.va.comcast.net] has quit [Ping timeout: 240 seconds]
14:27 -!- sandeepkr__ [~sandeep@111.235.64.4] has joined ##hplusroadmap
14:31 -!- sandeepkr_ [~sandeep@111.235.64.4] has quit [Ping timeout: 264 seconds]
14:36 < kanzure> lolz ran into the creator of second life
14:36 < kanzure> i forgot that california isn't completely awful
14:40 < kanzure> what was the audio recording device that maaku was looking at recently?
14:40 < kanzure> gecko something? geckowave? wristband something something
14:51 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Quit: Leaving]
14:51 -!- PatrickRobotham [uid18270@gateway/web/irccloud.com/x-gcngefrunzbmscgy] has quit [Quit: Connection closed for inactivity]
14:54 < kanzure> hmm http://kaptureaudio.com/ was not the right one
14:59 < kanzure> https://www.amazon.com/gp/product/B01B79K0ZW/
15:02 < kanzure> embryo vitrification works, apparently
15:03 < kanzure> hmm and fahy shows up as first google scholar result
15:06 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has joined ##hplusroadmap
15:07 < kanzure> https://www.indiegogo.com/projects/dracos-may-be-effective-against-all-viruses#/
15:07 < kanzure> they did a second campaign apparently: https://www.indiegogo.com/projects/draco-may-be-a-cure-for-all-viral-infections#/
15:07 < kanzure> oh.. i guess not.
15:07 < kanzure> oh i see. they used the same page again. that's lame.
15:10 -!- augur_ [~augur@noisebridge130.static.monkeybrains.net] has joined ##hplusroadmap
15:11 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has quit [Ping timeout: 272 seconds]
15:25 < streety> why develop these DRACOs against 15 different viruses and not include any that could be advanced to human clinical trials? It seems strange to now go back multiple steps to target a new virus that needs to be optimized again.
15:25 < kanzure> http://www.arxiv-sanity.com/
15:25 < kanzure> https://scirate.com/
15:25 < kanzure> http://gitxiv.com/
15:27 -!- CheckDavid [uid14990@gateway/web/irccloud.com/x-ijbzmqumxwdqpigr] has joined ##hplusroadmap
15:30 -!- zeysmo_ is now known as zeysmo
15:34 < fenn> .title https://www.amazon.com/gp/product/B01B79K0ZW/
15:34 < yoleaux> 500 Service Unavailable Error
15:34 < fenn> "Weefun 8GB Digital Voice Recorder Wristband & MP3 Music Player, USB Rechargeable"
15:34 < fenn> or maybe the pebble core
15:34 < kanzure> we should coerce maaku into doing a writeup of which exact machine learning thing he wants for voice recording and transcription
15:35 < kanzure> or, in particular, his design recommendation for such a monstrosity
15:49 < jrayhawk> kanzure: Maybe! I think I'll wait to see what the presentations a like before committing unless you want logistical help.
15:50 < kanzure> right, well, it's a good opportunity to shame me into visiting
15:51 < jrayhawk> I think we can provide you a mattress at this house, which will be a bit closer to downtown than e.g. nmz787's house.
15:51 < kanzure> an entire mattress golly
15:51 < jrayhawk> And food.
15:52 < kanzure> i was about to make a snide remark about the high life, but food would be nice, so... hm.
15:52 < fenn> i can provide beer concentrate in a metallized plastic pouch
15:53 < kanzure> make it adderall concentrate and you have a deal
15:53 < jrayhawk> You'd also get to meet the Beeminder folks, who are obsessive productivity theorists and would probably take an interest in you
15:53 < kanzure> all i can tell them is "i recommend massive quantities of brain damage and pokemon"
15:53 < jrayhawk> "also: amphetamines"
15:53 < kanzure> oh right
16:02 < kanzure> https://www.autodeskresearch.com/people/aaron-berliner
16:02 < kanzure> https://www.autodeskresearch.com/people/larry-peck
16:03 < kanzure> "cofounded a company called Acheron to began tinkering with combining synthetic biology with bioremediation methods for nuclear waste environmental engineering"
16:03 < kanzure> "After helping write some of the bioprinting code for Organovo’s organ printers, I transitioned to research in synthetic virology. We successfully created synthetic viruses, from digital text files, that kill bacteria. Currently I work on integrating aspects of synthetic virology, extremophile biology, and DNA nanotechnology. While working on Acheron and with Autodesk, I am pursuing a PhD in Biophysics at the University of California ...
16:03 < kanzure> ... Berkeley and the Arkin Laboratory on Martian Ecopoiesis"
16:05 < kanzure> "Designed optical systems for spatial light modulation using deformable mirro"
16:05 < kanzure> *mirrors
16:06 < kanzure> "Towards a Synthetic Biology Approach to Asteroid ISRU and Planetary Protection"
16:06 < kanzure> "Potential Applications for Bioelectrochemical Systems for Space Exploration"
16:06 < kanzure> "MEMS spatial light modulators for controlled optical transmission through nearly opaque materials"
16:07 < kanzure> "A Microfluidic Microgravity Microbial System For Synthetic Biology Unit Tests and Satellite Missions"
16:07 -!- augur_ [~augur@noisebridge130.static.monkeybrains.net] has quit [Remote host closed the connection]
16:08 < kanzure> http://acheron.bio/
16:10 < kanzure> "Beyond Berlin has signed an official Material Transfer Agreement with Lawrence Berkeley National Laboratory to received biological materials. A scientist [ask for name] at LBL has spent his career searching for rare extremophiles such as the radiation absorbing C. sphaerospermum and has been kind enough to send us our first samples for testing."
16:13 < kanzure> (cladosporium sphaerospermum)
16:13 -!- sh [~sh@89.101.222.213] has quit [Disconnected by services]
16:15 < streety> radiation absorbing? https://microbewiki.kenyon.edu/index.php/Cladosporium_sphaerospermum#The_use_of_ionizing_radiation.
16:18 < kanzure> "In light of recent accidents on nuclear power plants, particularly the one on Chernobyl power plant in 1986, it has been discovered that C. sphaerospermum can withstand high levels of radiation and use it to its advantage. Production of melanin by the fungus is linked to its ability to colonize areas of high radioactive contamination [16]. Moreover, in presence of radiation, C. sphaerospermum can thrive on high nutrient media as well as ...
16:18 < kanzure> ... on the minimal nutrition media. Studies conducted with samples from Chernobyl indicate that change in electronic properties of melanin induces fungal proliferation [16]. After exposure to radiation the electronic structure of melanin changes."
16:18 < kanzure> "They also demonstrated that the ability of melanin to transfer electrons in the NADH oxidation/reduction reaction increased 4-fold [16]. The stable free radicals in melanin can interact with high-energy electrons that can damage fungal DNA. The interaction of the free radicals created by gamma radiation with the stable radicals in melanin protects DNA from radiation damage because the free radicals are prevented from entering the cell ...
16:18 < kanzure> ... since melatonin is localized to the cell wall and extracellular space [16]. Moreover, the melanised fungal cells that were exposed to radiation levels 500 fold higher than background level grew considerably faster than nonmelanised fungus or the cells that received background level of radiation. Additional studies about the effects of radiation on C. sphaerospermum show directional growth of the fungus toward the source of radiation ...
16:18 < kanzure> ... [18]. Thus, it is possible that C. sphaerospermum, facilitated by melanin, can capture ionizing radiation and use it for metabolic energy [16]."
16:23 -!- sh [~sh@89.101.222.213] has joined ##hplusroadmap
16:25 < kanzure> made in space will be here in a few days
16:27 < kanzure> oh it was genehacker that mentioned them
16:43 -!- CuriousCat [~CuriousCa@unaffiliated/wye-naught/x-8734122] has quit [Quit: * *  *    *        *]
16:44 -!- gourneau [~gourneau@173.250.197.104.bc.googleusercontent.com] has quit [Ping timeout: 240 seconds]
16:53 < jrayhawk> i would guess bkero also has a room in Beaverton to offer you, and also likes interesting hardware
16:54 < bkero> I'm in Portland
16:54 < bkero> and I do have a guest room
16:54 < jrayhawk> Oh, possibly even better!
16:54 < bkero> depends on when
16:54 < jrayhawk> http://2016.oshwa.org/ early october
16:54 < bkero> ooo
16:54 < jrayhawk> for kanzure
16:54 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has joined ##hplusroadmap
16:54 < bkero> that is definitely a possibility, yes
16:55 < kanzure> i appreciate the recommendations but i would probably just get a hotel somewhere, and if i drag fenn along then i would probably put him with jrayhawk because he can then physically verify the jrayhawk vs srayhawk conspiracy
16:55 < jrayhawk> haha
17:03 -!- Aurelius_Laptop [~cpopell@static-108-28-104-83.washdc.fios.verizon.net] has joined ##hplusroadmap
17:30 < kanzure> .title https://www.youtube.com/watch?v=A-OQNwcKKS8
17:30 < yoleaux> One Punch Man - Saitama's OK Face - YouTube
17:31 < kanzure> not sure why everyone is upset about someone telling stephen hawking "i am right next to you and could kill you". it was probably just bad phrasing; maybe it's someone that goes around does mercy killings for paralyzed folks.
17:32 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has quit [Remote host closed the connection]
17:38 < jrayhawk> in context, it sounds more cluster-b "if i can't have you, nobody can" good/optimal/valuable/existent/internalized and externalized/bad/suboptimal/worthless/non-existent dichotomization
17:39 < kanzure> bitsummit conference in tokyo at the moment (indie video game development things)
17:51 < kanzure> heh theranos people
18:01 -!- irseeyou [~irseeyou@c-67-168-101-20.hsd1.wa.comcast.net] has joined ##hplusroadmap
18:13 < streety> kanzure: always seeing the best in people.
18:17 < kanzure> well someone has to give him a mercy killing at some point, damn
18:17 -!- Orpheon [~Orpheon@141.94.62.81.dynamic.wline.res.cust.swisscom.ch] has quit [Read error: Connection reset by peer]
18:18 < kanzure> face phenotype prediction from genome (from human longevity inc) https://www.ted.com/talks/riccardo_sabatini_how_to_read_the_genome_and_build_a_human_being/transcript?language=en
18:18 < streety> or restore function
18:32 -!- Aurelius_Laptop [~cpopell@static-108-28-104-83.washdc.fios.verizon.net] has quit [Ping timeout: 252 seconds]
18:34 -!- jaboja [~jaboja@vps.jaboja.pl] has quit [Ping timeout: 252 seconds]
19:15 -!- fleshtheworld [~fleshthew@2602:306:cf0f:4c20:c8b9:2c4b:6613:4e3c] has joined ##hplusroadmap
19:16 -!- Gurkenglas [Gurkenglas@dslb-178-005-223-183.178.005.pools.vodafone-ip.de] has quit [Ping timeout: 246 seconds]
19:25 < kanzure> juul: who is alicia j?
19:26 < kanzure> http://www.darpa.mil/program/living-foundries
19:26 < kanzure> "with the goal of compressing the biological design-build-test-learn cycle by at least 10 times in both time and cost while at the same time increasing the complexity of systems that are created"
19:32 < kanzure> "Biosynthesis of amphetamine analogs in plants" http://www.cell.com/trends/plant-science/abstract/S1360-1385(12)00056-8
19:41 -!- justanotheruser [~Justan@unaffiliated/justanotheruser] has quit [Read error: Connection reset by peer]
19:42 -!- justanotheruser [~Justan@unaffiliated/justanotheruser] has joined ##hplusroadmap
19:45 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has quit [Read error: Connection reset by peer]
20:01 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has joined ##hplusroadmap
20:19 -!- CuriousCat [~CuriousCa@unaffiliated/wye-naught/x-8734122] has joined ##hplusroadmap
20:26 < kanzure> "Farming amphetamines: Khat (Catha edulis Forsk.) a traditional plant with mild stimulating psychoactive and medicinal properties" http://link.springer.com/chapter/10.1007/978-94-017-9276-9_9
20:26 < kanzure> "Khat (Catha edulis Forsk., Celastraceae) is a flowering perennial shrub with a long history of use and cultivation in East Africa and the Arabian Peninsula. Young khat leaves are traditionally chewed in social gatherings to attain special states of mind, aimed especially at awakeness and enhanced mind focus. Since khat chewing contains amphetamine-like molecules and reportedly causes addiction among users it is banned in most countries, ...
20:26 < kanzure> ... but it is part of social life and legal in some countries. The main pharmacoactive compounds present in khat leaves are the phenylpropylamino alkaloids (S)-cathinone and (S)-cathine."
20:26 < kanzure> "L-Phenylalanine serves as a key biosynthetic precursor of phenylpropylalkaloids. Phenylalanine is converted by a series of not yet fully characterized reactions involving chain-shortening to benzaldehyde, then ligation to decarboxylated pyruvate, oxidation and incorporation of an amino group to yield (S)-cathinone, the most active compound accumulating in young leaves. (S)-Cathinone is subsequently reduced to (S)-cathine, the main ...
20:26 < kanzure> ... compound accumulated in mature leaves, but pharmacologically less active than (S)-cathinone. The pharmacological prospects of khat uses and some personal experiences of one of the authors in khat chewing are described here."
20:27 < kanzure> .wik khat
20:27 < yoleaux> "Catha edulis (khat, qat) is a flowering plant native to the Horn of Africa and the Arabian Peninsula. Among communities from these areas, khat chewing has a history as a social custom dating back thousands of years." — https://en.wikipedia.org/wiki/Khat
20:57 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has joined ##hplusroadmap
21:23 < kanzure> .title https://cuusoo.com/projects/49653
21:23 < yoleaux> The Mechanoids mark-1A Scouter is a fully articulating model comes with two twin guns/ pistoles and is able to fold into a square. Also 4 shootable rockets and the ability to bend into many poses. | Let's create together
21:23 < kanzure> .wik kuratas
21:23 < yoleaux> "Kuratas is a rideable and user-operated robot built by the Japanese company Suidobashi Heavy Industry. Billed as "the world's first giant boarding robot", the Kuratas was unveiled when the website was opened in 2012. It was demonstrated at Wonder Festival." — https://en.wikipedia.org/wiki/Kuratas
21:23 < kanzure> "In June 2015, MegaBots challenged Suidobashi Heavy Industry to its first robot duel confronting Kuratas versus their Mark II.[3]"
21:23 < kanzure> "As of 25 April 2013, Kuratas has a price tag of US$1,353,500 (¥134,555,495, or €1,040,976).[6]"
21:24 -!- PatrickRobotham [uid18270@gateway/web/irccloud.com/x-meijcznplbxfjadw] has joined ##hplusroadmap
21:28 -!- ArturShaik [~ArturShai@37.218.160.33] has joined ##hplusroadmap
22:02 -!- CheckDavid [uid14990@gateway/web/irccloud.com/x-ijbzmqumxwdqpigr] has quit [Quit: Connection closed for inactivity]
22:44 -!- irseeyou [~irseeyou@c-67-168-101-20.hsd1.wa.comcast.net] has quit [Quit: Leaving.]
22:52 -!- yashgaroth [~yashgarot@2602:306:35fa:d500:f5e0:f867:a11d:8d52] has quit [Quit: Leaving]
23:00 -!- AmbulatoryCortex [~Ambulator@173-31-155-69.client.mchsi.com] has quit [Read error: Connection reset by peer]
23:32 -!- CuriousCat [~CuriousCa@unaffiliated/wye-naught/x-8734122] has quit [Quit: * *  *    *        *]
23:51 -!- PatrickRobotham [uid18270@gateway/web/irccloud.com/x-meijcznplbxfjadw] has quit [Quit: Connection closed for inactivity]
--- Log closed Sun Jul 03 00:00:46 2016