--- Log opened Fri Aug 19 00:00:30 2016 00:07 -!- Cory [~C@unaffiliated/cory] has joined ##hplusroadmap 00:28 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Remote host closed the connection] 00:34 -!- augur [~augur@2602:304:cdac:e260:5dd:49cd:99:34c1] has joined ##hplusroadmap 00:38 -!- ebowden [~ebowden@1.152.96.93] has joined ##hplusroadmap 00:38 -!- ebowden [~ebowden@1.152.96.93] has quit [Changing host] 00:38 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 00:40 -!- cynsia [cyn@2600:3c03::f03c:91ff:fe79:d5d] has quit [Quit: Leaving] 00:43 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Remote host closed the connection] 00:43 -!- ebowden [~ebowden@1.152.96.93] has joined ##hplusroadmap 00:43 -!- ebowden [~ebowden@1.152.96.93] has quit [Changing host] 00:43 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 01:02 -!- ldlework [~ldlework@unaffiliated/ldlework] has joined ##hplusroadmap 01:03 < ldlework> kanzure: you still use paperbot? 01:05 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Remote host closed the connection] 01:15 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 01:22 -!- Burn_ [~Burn@pool-108-31-204-167.washdc.fios.verizon.net] has quit [Read error: Connection reset by peer] 01:29 < nmz787_> github STL diffs are pretty nice: https://github.com/nmz787/python-brlcad-tcl/commit/5e57bef2f8acac4e5609e526759c5503ec129088 01:29 < nmz787_> .title 01:29 < yoleaux> Added first implementation of 'connection points' which consist of a … · nmz787/python-brlcad-tcl@5e57bef · GitHub 01:33 -!- Burninate [~Burn@pool-108-31-204-167.washdc.fios.verizon.net] has joined ##hplusroadmap 02:02 -!- PatrickRobotham [uid18270@gateway/web/irccloud.com/x-zobldvbrzyipgcps] has quit [Quit: Connection closed for inactivity] 03:01 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap 03:21 -!- EddieAndDerek [aec80bc1@gateway/web/freenode/ip.174.200.11.193] has quit [Ping timeout: 264 seconds] 03:24 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Remote host closed the connection] 03:24 -!- Aurelius_Home2 [~cpopell@c-73-200-185-48.hsd1.va.comcast.net] has joined ##hplusroadmap 03:25 -!- ebowden [~ebowden@2001:8003:100e:c500:f1df:eaa0:d9ad:5733] has joined ##hplusroadmap 03:25 -!- ebowden [~ebowden@2001:8003:100e:c500:f1df:eaa0:d9ad:5733] has quit [Changing host] 03:25 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 03:26 -!- Aurelius_Home [~cpopell@c-73-200-185-48.hsd1.va.comcast.net] has quit [Ping timeout: 276 seconds] 03:28 -!- ebowden_ [~ebowden@CPE-101-180-249-107.lnse3.cha.bigpond.net.au] has joined ##hplusroadmap 03:28 -!- ebowden_ [~ebowden@CPE-101-180-249-107.lnse3.cha.bigpond.net.au] has quit [Changing host] 03:28 -!- ebowden_ [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 03:29 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Ping timeout: 260 seconds] 04:10 -!- BobaMa [bobama@kapsi.fi] has quit [Ping timeout: 276 seconds] 04:10 -!- BobaMa [bobama@kapsi.fi] has joined ##hplusroadmap 04:26 -!- BobaMa [bobama@kapsi.fi] has quit [Ping timeout: 276 seconds] 04:26 -!- BobaMa [bobama@kapsi.fi] has joined ##hplusroadmap 04:42 -!- Gurkenglas [Gurkenglas@dslb-178-005-223-183.178.005.pools.vodafone-ip.de] has joined ##hplusroadmap 05:11 -!- augur [~augur@2602:304:cdac:e260:5dd:49cd:99:34c1] has quit [Remote host closed the connection] 05:39 -!- ebowden_ [~ebowden@unaffiliated/ebowden] has quit [Remote host closed the connection] 05:41 -!- ebowden [~ebowden@101.180.249.107] has joined ##hplusroadmap 05:41 -!- ebowden [~ebowden@101.180.249.107] has quit [Changing host] 05:41 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 05:42 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Remote host closed the connection] 05:42 -!- ebowden [~ebowden@2001:8003:100e:c500:99eb:b02e:7b2b:fa02] has joined ##hplusroadmap 05:42 -!- ebowden [~ebowden@2001:8003:100e:c500:99eb:b02e:7b2b:fa02] has quit [Changing host] 05:42 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 05:51 < wrldpcmbl> Per the earlier discussion: Peter Rothman who just completed a thyroid regeneration trial is looking for something new to jump into. He's all about self-experimentation. 05:53 < wrldpcmbl> Thyroid? Maybe thymus. 05:59 -!- Aurelius_Work2 [~cpopell@209.48.69.2] has quit [Ping timeout: 244 seconds] 06:02 -!- Aurelius_Work [~cpopell@209.48.69.2] has joined ##hplusroadmap 06:02 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Quit: Leaving] 06:05 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap 06:50 -!- sandeepkr_ [~sandeepkr@182.75.187.110] has joined ##hplusroadmap 06:51 < kanzure> ldlework: paperbot is currently not in use at the moment. 06:54 -!- sandeepkr [~sandeepkr@182.75.187.110] has quit [Ping timeout: 244 seconds] 06:57 -!- sandeepkr__ [~sandeepkr@182.75.187.110] has joined ##hplusroadmap 07:00 -!- Aurelius_Work [~cpopell@209.48.69.2] has quit [Ping timeout: 244 seconds] 07:01 -!- sandeepkr_ [~sandeepkr@182.75.187.110] has quit [Ping timeout: 258 seconds] 07:08 -!- Aurelius_Work [~cpopell@209.48.69.2] has joined ##hplusroadmap 07:11 -!- augur [~augur@76-218-206-38.lightspeed.sntcca.sbcglobal.net] has joined ##hplusroadmap 07:16 -!- augur [~augur@76-218-206-38.lightspeed.sntcca.sbcglobal.net] has quit [Ping timeout: 244 seconds] 07:20 -!- PatrickRobotham [uid18270@gateway/web/irccloud.com/x-phpalrgwcbvcbbiw] has joined ##hplusroadmap 07:34 -!- CheckDavid [uid14990@gateway/web/irccloud.com/x-uqtkavoaohayholw] has joined ##hplusroadmap 08:03 < Regex__> http://medicalxpress.com/news/2016-08-revolutionary-method-brain-single-neuron-resolution.html 08:15 < kanzure> tsk tsk, link to the source, not the journalist garbage 08:16 < kanzure> oh it's mapseq. well in that case, read the channel logs. 08:20 < __mz_o> may you relink the paper. grep didn't provide the link 08:21 < kanzure> http://diyhpl.us/~bryan/papers2/neuro/High-throughput%20mapping%20of%20single%20neuron%20projections%20by%20sequencing%20of%20barcoded%20RNA%20-%202016.pdf 08:21 < kanzure> http://diyhpl.us/~bryan/papers2/neuro/Rosetta%20brains:%20A%20strategy%20for%20molecularly-annotated%20connectomics%20-%20Marblestone%20-%20Church%20-%20Boyden%20-%202014.pdf 08:21 < kanzure> http://diyhpl.us/~bryan/papers2/neuro/On%20optical%20detection%20of%20densely%20labeled%20synapses%20in%20neuropil%20and%20mapping%20connectivity%20with%20combinatorially%20multiplexed%20fluorescent%20synaptic%20markers%20-%20Mishchenko%20-%202010.pdf 08:21 < kanzure> http://diyhpl.us/~bryan/papers2/neuro/Reconstruction%20of%20complete%20connectivity%20matrix%20for%20connectomics%20by%20sampling%20neural%20connectivity%20with%20fluorescent%20synaptic%20markers%20-%20Mishchenko%20-%202011.pdf 08:22 < kanzure> "Fluorescent in situ sequencing (FISSEQ) of RNA for gene expression profiling in intact cells and tissues" http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4327781/ 08:22 < kanzure> http://gnusha.org/logs/2016-07-14.log 08:23 < kanzure> http://gnusha.org/logs/2016-07-13.log 08:25 < __mz_o> thank you 08:27 < kanzure> http://diyhpl.us/~bryan/papers2/neuro/Conneconomics:%20The%20economics%20of%20large-scale%20neural%20connectomics%20-%20Marblestone.pdf 08:27 < __mz_o> also I see its apache, but what is powering the wiki? 08:27 < __mz_o> is it just a git repo? 08:27 < kanzure> while you guys are here, please also read: 08:27 < kanzure> http://diyhpl.us/~bryan/papers2/neuro/Designing%20scalable%20biological%20interfaces%20-%20Marblestone.pdf 08:28 < kanzure> http://diyhpl.us/~bryan/papers2/neuro/Reconstruction%20and%20simulation%20of%20neocortical%20microcircuitry.pdf 08:28 < kanzure> http://diyhpl.us/~bryan/papers2/bio/Whole-body%20and%20whole-organ%20clearing%20and%20imaging%20techniques%20with%20single-cell%20resolution:%20toward%20organism-level%20systems%20biology%20in%20mammals%20-%20Susaki%20-%202016.pdf 08:28 < kanzure> http://diyhpl.us/~bryan/papers2/neuro/Physical%20principles%20for%20scalable%20neural%20recording%20-%20Marblestone.pdf 08:28 < kanzure> "Continuous genetic recording with self-targeting CRISPR-Cas in human cells" http://biorxiv.org/content/early/2016/05/20/053058 08:29 < kanzure> "Molecular recordings by directed CRISPR spacer acquisition" http://diyhpl.us/~bryan/papers2/bio/Molecular%20recordings%20by%20directed%20CRISPR%20spacer%20acquisition%20-%20Church%20-%202016.pdf 08:29 < kanzure> __mz_o: wiki is built using ikiwiki, it's essentially a git repository and text-to-html compiler thingy 08:30 < kanzure> instructions for pushing updates are on http://diyhpl.us/wiki/ or you can use https://github.com/kanzure/diyhpluswiki 09:14 -!- ArturShaik [~ArturShai@31.29.9.62] has quit [Ping timeout: 258 seconds] 10:00 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Remote host closed the connection] 10:38 < kanzure> online llvm-based c++ repl http://fiddle.jyt.io/ 10:45 -!- ebowden [~ebowden@2001:8003:100e:c500:99eb:b02e:7b2b:fa02] has joined ##hplusroadmap 10:45 -!- ebowden [~ebowden@2001:8003:100e:c500:99eb:b02e:7b2b:fa02] has quit [Changing host] 10:45 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 10:49 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Ping timeout: 260 seconds] 10:57 -!- Orpheon [~Orpheon@46.140.52.182] has joined ##hplusroadmap 11:02 -!- PatrickRobotham [uid18270@gateway/web/irccloud.com/x-phpalrgwcbvcbbiw] has quit [Quit: Connection closed for inactivity] 11:18 -!- nildicit [~nildicit@unaffiliated/nildicit] has joined ##hplusroadmap 11:33 -!- Gurkenglas [Gurkenglas@dslb-178-005-223-183.178.005.pools.vodafone-ip.de] has quit [Ping timeout: 265 seconds] 11:56 -!- Gurkenglas [Gurkenglas@dslb-178-005-223-183.178.005.pools.vodafone-ip.de] has joined ##hplusroadmap 11:57 -!- cynsia [cyn@2600:3c03::f03c:91ff:fe79:d5d] has joined ##hplusroadmap 11:59 -!- augur [~augur@2602:304:cdac:e260:e932:4e76:7f45:67c3] has joined ##hplusroadmap 12:03 -!- nildicit [~nildicit@unaffiliated/nildicit] has left ##hplusroadmap ["Leaving"] 12:17 < ldlework> kanzure: has it bit rotted or do you expect it to work 12:18 < kanzure> it works. 12:18 < ldlework> why don't you use it anymore 12:18 < kanzure> zotero setup is sort of annoying. that might have som bitrot. 12:18 < ldlework> kanzure: have you considered producing a docker image? 12:19 < ldlework> also sorry for the questions randomly 12:19 < kanzure> unfortunately if i was to run a docker container my sysadmin would murder me 12:19 < ldlework> I found it on github 12:19 < ldlework> kanzure: oh yeah? 12:19 < kanzure> yeah he's great. 12:19 < kanzure> always looking out for people, 'n such 12:20 < ldlework> lol can't tell whether you're being sarcastic :) 12:20 < ldlework> This is a wierd channel, I never heard of it before 12:20 < kanzure> there's a little bit of sarcasm but also reality is a blend of everything 12:21 < ldlework> What is "hplusroadmap" supposed to mean 12:21 < kanzure> hplusroadmap is described here- http://diyhpl.us/wiki/hplusroadmap 12:22 < ldlework> Neat. 12:23 < ldlework> Is neuroscience a welcome topic? 12:23 < ldlework> I'm guessing so. 12:23 < kanzure> yep 12:23 < kanzure> here's some stuff http://diyhpl.us/~bryan/papers2/neuro/ 12:23 < ldlework> kanzure: have you heard of the Attention Schema Theory by Graziano? 12:24 < ldlework> I wonder if you could tell me how to feel about it 12:24 < kanzure> yes that was mentioned in this one: 12:24 < kanzure> http://diyhpl.us/~bryan/papers2/neuro/Delegation%20to%20automaticity:%20the%20driving%20force%20for%20cognitive%20evolution%3f.pdf 12:25 < kanzure> it was recently mentioned here https://news.ycombinator.com/item?id=11853151 12:25 < ldlework> kanzure: I read Graziano's paper directly, but I'm not expert. Just wondering what others think. 12:26 < kanzure> anyway, i don't really care about consciousness and i think it's a bad idea 12:26 < ldlework> Well, I'm not super interested in the subject experience bit either 12:26 < kanzure> like the question about "subjective experience" is just totally meaningless to me. why should i care whether it's subjective or not? 12:27 < ldlework> I just think its really cool to think that you have attention, an emergent process of signal competition 12:27 < kanzure> i strongly doubt that i have attention 12:27 < ldlework> and then you have another system that "learns" the behavior of this system 12:27 < ldlework> erm... 12:27 < kanzure> or self-awareness. in fact most girls agree with this assessment :). 12:27 < ldlework> hehe 12:28 < ldlework> I like the idea that, since various parts of your brain cannot "query" a process that the brain builds up a model of its behavior, so that other parts of the brain can know what's being attended to 12:28 < kanzure> there was one about some pile of neurons that compute saliency or something, 12:28 < ldlework> I find a lot of enjoyment at sort of just ... I don't know taking in how elegant things can be 12:29 < kanzure> http://diyhpl.us/~bryan/papers2/neuro/The%20expected%20value%20of%20control:%20an%20integrative%20theory%20of%20anterior%20cingulate%20cortex%20function.pdf 12:29 < kanzure> oh that's called navel gazing 12:29 < ldlework> yeah that 12:30 < ldlework> if you want to equate wonderment with narrowmindedness I suppose :) 12:32 < kanzure> paperbot needs a component written to query across multiple ezproxy servers, or to fetch from scihub instead of only submitting to scihub 12:33 < ldlework> kanzure: if you are interested in improving paperbot I might be motivated to try to build a nice image for it 12:33 < ldlework> There are some other channels on freenode that could benefit from a thing like paperbot (if I understand its function correctly) 12:39 < kanzure> i am sure others would appreciate that kind of pull requet 12:39 < kanzure> .. pull request 12:48 -!- ebowden [~ebowden@2001:8003:100e:c500:99eb:b02e:7b2b:fa02] has joined ##hplusroadmap 12:48 -!- ebowden [~ebowden@2001:8003:100e:c500:99eb:b02e:7b2b:fa02] has quit [Changing host] 12:48 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 12:53 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Ping timeout: 260 seconds] 12:56 -!- augur [~augur@2602:304:cdac:e260:e932:4e76:7f45:67c3] has quit [Remote host closed the connection] 12:58 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Quit: Leaving] 12:58 -!- Aurelius_Work [~cpopell@209.48.69.2] has quit [Ping timeout: 260 seconds] 13:05 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap 13:06 -!- Aurelius_Work [~cpopell@209.48.69.2] has joined ##hplusroadmap 13:12 -!- jaboja [~jaboja@2a00:f41:385e:6339:de85:deff:fe55:967a] has joined ##hplusroadmap 13:35 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Ping timeout: 260 seconds] 13:40 -!- cynsia_ [cyn@2600:3c03::f03c:91ff:fe79:d5d] has joined ##hplusroadmap 13:41 -!- cynsia_ [cyn@2600:3c03::f03c:91ff:fe79:d5d] has quit [Client Quit] 13:41 -!- cynsia_ [cyn@2600:3c03::f03c:91ff:fe79:d5d] has joined ##hplusroadmap 13:42 -!- cynsia [cyn@2600:3c03::f03c:91ff:fe79:d5d] has quit [Ping timeout: 250 seconds] 13:42 -!- cynsia_ is now known as cynsia 13:42 -!- ebowden [~ebowden@2001:8003:100e:c500:99eb:b02e:7b2b:fa02] has joined ##hplusroadmap 13:42 -!- ebowden [~ebowden@2001:8003:100e:c500:99eb:b02e:7b2b:fa02] has quit [Changing host] 13:42 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 13:42 -!- cynsia [cyn@2600:3c03::f03c:91ff:fe79:d5d] has quit [Client Quit] 13:42 -!- cynsia [cyn@2600:3c03::f03c:91ff:fe79:d5d] has joined ##hplusroadmap 13:47 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Ping timeout: 260 seconds] 13:56 -!- abstractmonkey [~abstractm@pool-72-74-36-8.bstnma.fios.verizon.net] has joined ##hplusroadmap 13:56 < abstractmonkey> 2/ 14:03 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has joined ##hplusroadmap 14:05 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap 14:20 -!- jaboja [~jaboja@2a00:f41:385e:6339:de85:deff:fe55:967a] has quit [Read error: Connection reset by peer] 14:26 -!- chris_999 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap 14:28 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Ping timeout: 260 seconds] 14:28 -!- chris_999 is now known as chris_99 14:32 -!- jaboja [~jaboja@2a00:f41:385e:6339:de85:deff:fe55:967a] has joined ##hplusroadmap 14:57 < chris_99> does anyone think 3d printers could come down a lot more in price, i've not really seen a price graph per year 14:57 < kanzure> "The people I know who are trying it have a version where each benzene ring can attach to a different cysteine - so it just rips it apart depending on its isomer. The trouble is designing the cysteines such that they can form both connections to the azo benzene since it is somewhat geometrically constrained." 15:08 -!- irseeyou [~irseeyou@c-67-168-101-20.hsd1.wa.comcast.net] has joined ##hplusroadmap 15:13 -!- ebowden [~ebowden@2001:8003:100e:c500:99eb:b02e:7b2b:fa02] has joined ##hplusroadmap 15:13 -!- ebowden [~ebowden@2001:8003:100e:c500:99eb:b02e:7b2b:fa02] has quit [Changing host] 15:13 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 15:17 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Ping timeout: 260 seconds] 16:03 < kanzure> thesnark: *poke* 16:04 < thesnark> hey kanzyre 16:04 < thesnark> erm 16:04 < thesnark> kaz 16:04 < thesnark> fuck 16:04 < thesnark> kanzure 16:06 -!- jaboja [~jaboja@2a00:f41:385e:6339:de85:deff:fe55:967a] has quit [Read error: Connection reset by peer] 16:07 -!- ebowden [~ebowden@CPE-101-180-249-107.lnse3.cha.bigpond.net.au] has joined ##hplusroadmap 16:07 -!- ebowden [~ebowden@CPE-101-180-249-107.lnse3.cha.bigpond.net.au] has quit [Changing host] 16:07 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 16:11 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Ping timeout: 260 seconds] 16:12 -!- jaboja [~jaboja@2a00:f41:385e:6339:de85:deff:fe55:967a] has joined ##hplusroadmap 16:14 < kanzure> molecular assemblies seems to have requested that the content of their patent application be withdrawn or something? not sure what's going on there 16:14 < kanzure> https://patentimages.storage.googleapis.com/pdfs/US9279149.pdf 16:14 < kanzure> http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=9279149.PN.&OS=PN/9279149&RS=PN/9279149 16:14 < kanzure> content is available there^ 16:14 < kanzure> "The invention provides improved methods for synthesizing polynucleotides, such as DNA and RNA, using enzymes and specially designed nucleotide analogs. Using the methods of the invention, specific sequences of polynucleotides can be synthesized de novo, base by base, in an aqueous environment, without the use of a nucleic acid template. Because the nucleotide analogs have an unmodified 3' OH, i.e., as found in "natural" deoxyribose and ... 16:14 < kanzure> ... ribose molecules, the analogs result in natural polynucleotides suitable for incorporation into biological systems." 16:18 < kanzure> ah here we go, http://pimg-fpiw.uspto.gov/fdd/49/791/092/0.pdf 16:31 -!- abstractmonkey [~abstractm@pool-72-74-36-8.bstnma.fios.verizon.net] has quit [Remote host closed the connection] 16:43 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Quit: Leaving] 16:49 -!- cynsia [cyn@2600:3c03::f03c:91ff:fe79:d5d] has quit [Quit: Leaving] 16:58 -!- jaboja [~jaboja@2a00:f41:385e:6339:de85:deff:fe55:967a] has quit [Read error: Connection reset by peer] 17:07 -!- jaboja [~jaboja@2a00:f41:385e:6339:de85:deff:fe55:967a] has joined ##hplusroadmap 17:25 -!- irseeyou [~irseeyou@c-67-168-101-20.hsd1.wa.comcast.net] has quit [Quit: Leaving.] 17:38 -!- ebowden [~ebowden@101.180.249.107] has joined ##hplusroadmap 17:38 -!- ebowden [~ebowden@101.180.249.107] has quit [Changing host] 17:38 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 17:42 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Ping timeout: 260 seconds] 17:48 < CaptHindsight> cleavable couplers/linkers 17:49 < kanzure> there are many. 17:49 < CaptHindsight> and they recycle the unused portions 17:52 < CaptHindsight> at least you'll be able to buy or make these 17:52 -!- yashgaroth [~yashgarot@2602:306:35fa:d500:f5e0:f867:a11d:8d52] has joined ##hplusroadmap 17:54 < CaptHindsight> were the previous patents on cleavable linkers not broad enough? 17:54 < kanzure> probably this is just a random land grab. "take previous efforts, apply to nucleotides". 17:55 < CaptHindsight> seems like it 17:55 -!- poohbear is now known as banquetbear 17:55 < kanzure> iirc these people have are related to something about oligonucleotide synthesis methods 17:56 < kanzure> this was mentioned in the ancient backlogs; i don't remember the specifics. maybe it was something about the original abi machines? 17:57 < CaptHindsight> http://www.molecularassemblies.com/team.html 17:57 < kanzure> "before joining Applied Biosystems as the 9th employee ... There he hired and led the R&D group that commercialized phosphoramidite oligonucleotide synthesis and the Models 380A, 380B and 381 DNA synthesizers" 17:57 < CaptHindsight> oligonucleotide synthesis for fun and profit 17:58 < CaptHindsight> well profit anyway 17:59 -!- jaboja [~jaboja@2a00:f41:385e:6339:de85:deff:fe55:967a] has quit [Remote host closed the connection] 18:14 < nmz787_> did I mention that lightning terminator company said no to selling/working with a(another) DNA synthesis project? 18:32 -!- ebowden [~ebowden@2001:8003:100e:c500:99eb:b02e:7b2b:fa02] has joined ##hplusroadmap 18:32 -!- ebowden [~ebowden@2001:8003:100e:c500:99eb:b02e:7b2b:fa02] has quit [Changing host] 18:32 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 18:37 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Ping timeout: 260 seconds] 18:46 < streety> I think so nmz787_ something along the lines of get back in touch later in case anything changes? 18:50 < nmz787_> ah, yeah 18:51 -!- cynsia [cyn@2600:3c03::f03c:91ff:fe79:d5d] has joined ##hplusroadmap 18:53 < fenn> what's this about lightning terminators? 18:55 < fenn> "Lasergen’s key technology, Lightning Terminators™, provides unique photocleavable terminator chemistry with faster reaction kinetics and robust cleavage properties." 18:55 < fenn> meh 18:56 -!- DumpsterDiver [~DumpsterD@pool-72-83-63-211.washdc.east.verizon.net] has joined ##hplusroadmap 18:56 < fenn> hello DumpsterDiver, been doing a bit of that myself lately 18:56 < kanzure> for all you know they mean a different kind of dumpster 18:56 < fenn> words, what are they? 18:57 < fenn> more slippery than salmon, as soon as you look closely they turn into something else, it's like living in a dream 19:01 < kanzure> were you the one that told me about librivox? 19:01 < kanzure> or am i just confusing this with the something about libvorbis? 19:01 < kanzure> -the 19:02 -!- jcorgan [~jcorgan@unaffiliated/jcorgan] has quit [Ping timeout: 244 seconds] 19:03 < fenn> seems like something that would have come up recently wrt labeled audio transcription training corpus 19:03 < fenn> anyway it wasn't me 19:04 < kanzure> no it was years ago 19:06 < DumpsterDiver> Why punt a dildo. Not a bsd field position all things considered 19:08 < fenn> gnusha.org/logs/2010-06-06.log:11:56 < fenn> fun to see people i know on here http://www.voxforge.org/home/downloads/metrics 19:10 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has quit [Quit: hacked by chinese] 19:20 < fenn> hmm p2p yak shaving/yak trading sounds like a good idea 19:20 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has joined ##hplusroadmap 19:22 < kanzure> yak genocide 19:23 < fenn> yak derivatives 19:25 < kanzure> thesnark: *poke* 19:31 < kanzure> fenn: perhpas you could look at the current state of the polymerase draft and offer comments or reorganizing the outline? 19:32 < fenn> sounds like work 19:32 -!- ebowden [~ebowden@2001:8003:100e:c500:99eb:b02e:7b2b:fa02] has joined ##hplusroadmap 19:32 -!- ebowden [~ebowden@2001:8003:100e:c500:99eb:b02e:7b2b:fa02] has quit [Changing host] 19:32 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 19:34 -!- banquetbear is now known as poohbear 19:36 < kanzure> er, yes, porobably 19:37 < fenn> i seem to have misplaced the URL 19:37 < fenn> btw how is the ultrasound thingy coming along? 19:37 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Ping timeout: 260 seconds] 19:45 < fenn> ah i found it in a PM 19:47 -!- irseeyou [~irseeyou@c-67-168-101-20.hsd1.wa.comcast.net] has joined ##hplusroadmap 19:55 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 20:10 < maaku> Is there any basis for B12 as a energy/metabolism booster? 20:23 < maaku> Well there is no UL so I guess it doesn't hurt 20:33 -!- sandeepkr__ [~sandeepkr@182.75.187.110] has quit [Ping timeout: 265 seconds] 20:33 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Remote host closed the connection] 20:40 -!- ebowden [~ebowden@2001:8003:100e:c500:c90b:a79e:f7f7:280d] has joined ##hplusroadmap 20:40 -!- ebowden [~ebowden@2001:8003:100e:c500:c90b:a79e:f7f7:280d] has quit [Changing host] 20:40 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 20:41 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Remote host closed the connection] 20:43 -!- ebowden [~ebowden@2001:8003:100e:c500:14cc:e49d:404:7550] has joined ##hplusroadmap 20:43 -!- ebowden [~ebowden@2001:8003:100e:c500:14cc:e49d:404:7550] has quit [Changing host] 20:43 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 20:50 -!- ArturShaik [~ArturShai@31.29.9.62] has joined ##hplusroadmap 20:54 -!- Gurkenglas [Gurkenglas@dslb-178-005-223-183.178.005.pools.vodafone-ip.de] has quit [Ping timeout: 244 seconds] 20:57 -!- sandeepkr [~sandeepkr@182.75.187.110] has joined ##hplusroadmap 21:03 < kanzure> oh right, ultrasoud stuff 21:39 -!- irseeyou [~irseeyou@c-67-168-101-20.hsd1.wa.comcast.net] has quit [Quit: Leaving.] 21:40 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Remote host closed the connection] 21:48 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 22:00 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has quit [Read error: Connection reset by peer] 22:12 -!- drewbot [~cinch@ec2-54-81-235-167.compute-1.amazonaws.com] has quit [Remote host closed the connection] 22:12 -!- drewbot [~cinch@ec2-54-196-163-168.compute-1.amazonaws.com] has joined ##hplusroadmap 22:25 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has quit [Remote host closed the connection] 22:31 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Remote host closed the connection] 22:34 -!- ebowden [~ebowden@CPE-101-180-249-107.lnse3.cha.bigpond.net.au] has joined ##hplusroadmap 22:34 -!- ebowden [~ebowden@CPE-101-180-249-107.lnse3.cha.bigpond.net.au] has quit [Changing host] 22:34 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 22:43 -!- yashgaroth [~yashgarot@2602:306:35fa:d500:f5e0:f867:a11d:8d52] has quit [Quit: Leaving] 22:56 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Remote host closed the connection] 23:22 -!- augur [~augur@2602:304:cdac:e260:5c23:dac4:bb4f:f98a] has joined ##hplusroadmap 23:29 -!- zeysmo [VwSkU4a294@columba.uberspace.de] has quit [Ping timeout: 252 seconds] 23:29 -!- zeysmo [x2Bl4etLhW@columba.uberspace.de] has joined ##hplusroadmap 23:40 -!- jcorgan [~jcorgan@unaffiliated/jcorgan] has joined ##hplusroadmap 23:40 -!- ebowden [~ebowden@2001:8003:100e:c500:9040:208d:afb5:d064] has joined ##hplusroadmap 23:40 -!- ebowden [~ebowden@2001:8003:100e:c500:9040:208d:afb5:d064] has quit [Changing host] 23:40 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 23:45 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Ping timeout: 260 seconds] 23:49 -!- nefercheprure [tma@twin.jikos.cz] has joined ##hplusroadmap 23:50 -!- gwollon [~gwillen@unaffiliated/gwillen] has joined ##hplusroadmap 23:50 -!- ybit [~ybit@unaffiliated/ybit] has joined ##hplusroadmap 23:54 -!- cynsia [cyn@2600:3c03::f03c:91ff:fe79:d5d] has quit [Quit: Leaving] 23:54 -!- nnnn20430_ [nnnn@lightning.bouncer.ml] has joined ##hplusroadmap 23:54 -!- Netsplit *.net <-> *.split quits: andytoshi, gwillen, hylleddin, midnightmagic, nnnn20430, TMA, ybit_, Dumuzi 23:55 -!- nnnn20430_ is now known as nnnn20430 23:56 -!- Netsplit over, joins: midnightmagic --- Log closed Sat Aug 20 00:00:30 2016