--- Log opened Wed Dec 28 00:00:21 2016
--- Day changed Wed Dec 28 2016
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06:35 < kanzure> "Super-resolution Imaging of Synaptic and Extra-synaptic Pools of AMPA Receptors with Different- sized Fluorescent Probes" http://biorxiv.org/content/early/2016/12/27/096966 https://twitter.com/biorxiv_neursci/status/813942699879497729
06:36 < kanzure> "Quantitative mRNA Imaging Throughout the Entire Drosophila Brain" http://biorxiv.org/content/early/2016/12/22/096388 https://twitter.com/biorxiv_neursci/status/812160906155200516
06:36 < kanzure> "We describe a fluorescence in situ hybridization method that permits detection of the localization and abundance of single mRNAs (smFISH) in cleared whole-mount adult Drosophila brains. The approach is rapid, multiplexable and does not require molecular amplification; it allows facile mRNA expression quantification with subcellular resolution on a standard confocal microscope. Using a custom ...
06:36 < kanzure> ...Bessel Beam-Structured Illumination microscope (BB-SIM), we further demonstrate single-mRNA detection across the entire brain sample."
06:40 < kanzure> "Transcranial stimulation enhances memory-relevant sleep oscillations and their functional coupling in mild cognitive impairment" -freenode JayDugger http://biorxiv.org/content/early/2016/12/21/095588
06:40 < kanzure> "visual declarative memory was improved by so-tDCS compared to sham stimulation"
06:40 < kanzure> ( https://twitter.com/biorxiv_neursci/status/811692837817487361 )
06:41 -!- jcluck is now known as cluckj
06:51 < JayDugger> Thank you, kanzure. Got it.
06:54 < kanzure> https://corte.si/posts/code/mitmproxy/announce_1_0/index.html
06:55 < kanzure> hehe using mitmproxy's web interface to man-in-the-middle mitmproxy's web interface https://uploads.maximilianhils.com/2016-12/2016-12-26_21-16-15.png
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07:35 < kanzure> https://twitter.com/bxv_molbiol
07:37 < kanzure> https://twitter.com/ribosome_papers
07:40 < kanzure> "Cleanliness in context: reconciling hygiene with a modern microbial perspective" http://biorxiv.org/content/early/2016/12/20/095745
07:41 < kanzure> you could probably rig up some bacteria to infect humans during surgery as an opportunistic bacteria... then kill the bacteria with a kill switch at the conclusion of surgery (instead of having other infectious material proliferate).
07:41 < kanzure> or, why don't surgeons do a gel spraydown for body cavity surgery? it's probably better to have gel contact than prolonged contact with circulating air anyway.
07:46 < kanzure> "StackGAN: Text to Photo-realistic Image Synthesis with Stacked Generative Adversarial Networks"  https://arxiv.org/abs/1612.03242
07:46 < kanzure> that would be fun to run on top of irc logs...
07:48 < kanzure> "Scaling Memory-Augmented Neural Networks with Sparse Reads and Writes" https://arxiv.org/abs/1610.09027
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08:20 < kanzure> "Activity-dependent expression of reporter proteins at dendritic spines for synaptic activity mapping and optogenetic stimulation" http://biorxiv.org/content/early/2016/12/21/095984 https://twitter.com/biorxiv_neursci/status/811692829093351424
08:21 < kanzure> "... Therefore it would be important to develop methods to tag active synapses for mapping functionally active connections and to selectively stimulate or interfere with active synapses. Here we introduce an approach to express light-sensitive membrane channels at synapses in an activity-dependent way by means of RNA and protein regulatory sequences. This approach is based on the local express...
08:21 < kanzure> ...ion of reporter proteins, including opto-genetic probes, at activated synapses and will allow the mapping of previously active synapses and the re-activation of the neuron only at these sites. This will allow extending the investigation of memory processes beyond the current neuron tagging technologies, whose resolution is limited at the cellular scale. Thus, it will be possible to unveil and ...
08:21 < kanzure> ...recall the synaptic engram out of the global set of synapses."
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08:56 < chris_99> afternoon.  Has anyone used nanoparticles before per chance?
08:56 < yoleaux> 24 Dec 2016 23:34Z <nmz787> chris_99: this is the closest I can come up with... it's a bit different than what I saw demonstrated... but looks similar enough I think: http://iopscience.iop.org.sci-hub.cc/article/10.1088/2040-8978/18/12/123001/meta
08:56 < yoleaux> 24 Dec 2016 23:35Z <nmz787> chris_99: "Exploiting metamaterials, plasmonics and nanoantennas concepts in silicon photonics"
08:56 < yoleaux> 25 Dec 2016 02:22Z <cluckj> chris_99: https://www.amazon.com/Citizen-Science-Digital-Age-Engagement/dp/0817319433/
08:56 < chris_99> oh cheers nmz787 and cluckj
09:09 < cluckj> np
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10:14 < nmz787_w> :P
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11:37 < nmz787_w> chris_99: thought you might like this http://hackaday.com/2016/12/28/skidl-script-your-circuits-in-python/
11:38 < chris_99> oh interesting
11:38 < chris_99> cheers
11:38 < chris_99> i played a little with scripting the pcb traces with kicad, so that looks nifty
11:39 < chris_99> just looking @ https://designintools.intel.com/product_p/itpxdpsvt.htm which seems intriguing
11:46 < nmz787_w> ah, what for?
11:46 < chris_99> i was just wondering what jtag over dci, lets you do, there seems to be a 33c3 talk about it, but i need to listen to it with audio
11:48 < nmz787_w> hmm, interesting
11:48 < nmz787_w> link?
11:48 < chris_99> https://media.ccc.de/v/33c3-8069-tapping_into_the_core
11:51 < nmz787_w> lately I have been trying to learn about all the different access-methods/protocols for such CPUs, and even the protocols between sub-blocks in the chip
11:53 < chris_99> cool, what do you mean by "protocols between sub-blocks in the chip", what would those be?
11:55 < __mz_o> i think he means the raw digital multiwire connections
11:56 < nmz787_w> one example of IP to IP within an SoC would be: https://en.wikipedia.org/wiki/Advanced_Microcontroller_Bus_Architecture#Advanced_Peripheral_Bus_.28APB.29
11:56 < chris_99> oh interesting
11:56 < nmz787_w> or http://chipdesignmag.com/sld/blog/tag/iosf/
11:57 < nmz787_w> https://en.wikipedia.org/wiki/Open_Core_Protocol
11:57 < nmz787_w> "Neither Altera nor Xilinx, the two largest FPGA vendors, supports this protocol."  :P
11:58 < chris_99> heh
11:59 < chris_99> i've got my xilinx board now, need to play with it soon
11:59 < nmz787_w> from what I am understanding, basically any network might work between components/blocks/peripherals/IPs... but these protocols are optimized based on information theory of the specific application (I guess chip information transfer has some statistical features that allow better optimization with some specialization)
12:00 < nmz787_w> i.e. they might have been able to use SPI or I2C... but it wasn't optimal for some reason (probably trial and error through the years, combined with theoretical projections)
12:01 < chris_99> ah hmm
12:02 < chris_99> isn't i2c typically used for low data rates though for some reason?
12:02 < nmz787_w> right
12:02 < nmz787_w> so not optimal for a high-bandwidth CPU to memory bus
12:04 < nmz787_w> so then they came up with some other protocol... which can be both electrical wire standards (i.e. ensuring analog/signal integrity), but also how the API is formed (i.e. what signals do what, how data is structured, how things syncronize, etc)
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19:28 < kanzure> blort
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22:55  * jcorgan ponders the existential significance of "blort" as a post-modern expression of identity in a modern age of faceless internet communications and ephemeral social groupings
22:57 < jcorgan> or maybe, sometimes a blort is just a blort
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--- Log closed Thu Dec 29 00:00:51 2016