--- Log opened Thu Jan 26 00:00:15 2017
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06:35 < kanzure> blort
06:36 < JayDugger> trolb?
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06:48 < kanzure> i forgot how boring most AAAI papers sound http://www.aaai.org/Conferences/AAAI/2017/aaai17accepted-papers.pdf
06:51 < kanzure> .title https://tools.ietf.org/html/rfc8041
06:51 < yoleaux> RFC 8041 - Use Cases and Operational Experience with Multipath TCP
06:51 < kanzure> https://tools.ietf.org/wg/mptcp/
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06:54 < kanzure> https://www.onioncat.org/about-onioncat/
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09:58 < archels_> "Let's not glorify [...] too much (or at all). His [...] was useful, but it was never healthy that such an important resource was curated by a single nutcase."
10:00 < kanzure> whowhat
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10:03 < JayDugger> Too widely applicable. We talking keys to atomic arsenals here, or what?
10:07 < archels_> somebody posted this in reference to Jeffrey Beall, and his list of predatory publishers that was apparently just taken offline
10:09 < kanzure> probably on the wayback machine
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10:25 < JayDugger> Thank you, archels_.
10:37 < kanzure> .title https://news.ycombinator.com/item?id=13483442
10:37 < yoleaux> Python to Circuits | Hacker News
10:37 < chris_99> nmz787, mentioned that a while ago iirc, looks interesting
10:39 < kanzure> yes i was going to cc him
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10:40 < kanzure> .title https://github.com/JoinMarket-Org/joinmarket/issues/634
10:40 < yoleaux> Make tumbler idempotent [$1,000 bounty] ? Issue #634 ? JoinMarket-Org/joinmarket ? GitHub
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11:47 < nmz787_w> yeah I feel like I saw that xess thing
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12:33 < delinquentme> nmz787 kanzure who in here is doing protein wet lab or crystalography work?
12:34 < kanzure> yashgaroth
12:34 < kanzure> not crystallography though
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13:22 < kanzure> https://worldchess.com/2017/01/25/special-report-new-study-finds-performance-enhancing-drugs-for-chess/
13:22 < delinquentme> samn
13:22 < delinquentme> hes not online
13:22 < delinquentme> also kanzure are you close w juul ?
13:22 < delinquentme> hes not responsive to me requests.
13:22 < kanzure> "Methylphenidate, modafinil, and caffeine for cognitive enhancement in chess: A double-blind, randomised controlled trial" http://www.europeanneuropsychopharmacology.com/article/S0924-977X(17)30019-6/abstract
13:23 < delinquentme> im trying to get the plasmid that makes ecoli smell like straberries.
13:24 < kanzure> you could also ask the diybio people https://groups.google.com/group/diybio
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13:31 < kanzure> iaglium: greetings
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14:00 < sachy> The caffeine/ritalin effect of deeper (means too-slow in blitz games) position analysis is generally known (and used) on country+ level
14:01 < sachy> At least in czech rep.
14:06 < Jenda`> that something is used does not imply it really has effect, for example the homeopatic drug Oscillococcinum is pretty popular and advertised here as well...
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15:40 < nmz787_w> strawberry e.coli, huh
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15:58 < juul> delinquentme: i tried to respond but you were disconnected from irc
16:00 < juul> delinquentme: working with a non-standard strain of e. coli that's spending a bunch of resources making it smell nice is probably a bad idea for almost any type of work i can imagine. Better to just buy some strawberry/banana scent
16:00 < juul> i don't have that plasmid anyway
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16:06 < delinquentme> juul, i was told its under lock and key for academics by endys operation
16:07 < delinquentme> and on the metabolic overhead: sure ... but i'd still be interested in trying it out :D
16:07 < delinquentme> our lab stinks rn :D
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16:46 < juul> delinquentme: i will check what its status is next time i go to the lab but it might be restricted by an UBMTA in which case it would have to be re-synthesized in order to liberate it
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16:59 < delinquentme> juul, if you could find it I could totally invite you over to check out our production labs :D
16:59 < delinquentme> were growing critters for products :D
17:01 < juul> ah. where's your lab?
17:01 < juul> but something limited to academics only sounds like UBMTA
17:01 < delinquentme> allegedly its open source though ?
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17:14 < delinquentme> juul, ^
17:16 < juul> what does open source mean for biology?
17:16 < juul> copyright does not apply so you can't use any open source license or similar
17:17 < juul> does it mean that it's free of patents? how would anyone verify that?
17:17 < juul> ok so it might mean that people have reasonable confidence that it is not patent encumbered
17:18 < juul> then how did you get the DNA? did you get it from another university or from addgene? then it's probably covered by the UBMTA so you won't be able to share it with anyone
17:19 < juul> did you synthesize it from scratch? hurray! you may be able to share it, depending on whether you're an academic institution and how the legal department at your institution/corporation feels
17:19 < juul> but wait! did you read the terms of use from the synthesis company? many synthesis companies impose rather severe restrictions on what you can do with your synthesized DNA, e.g. no reselling
17:20 < juul> but you can prooobably share it for free
17:20 < juul> it's a mess
17:21 < juul> especially since a lot of constructs have parts from various places
17:22 < juul> e.g. a plasmid ordered from a commercial vendor or from addgene which comes with its own restrictive terms which has been combined with synthesized DNA with another set of terms
17:23 < juul> BioBricks foundation is launching the OMTA: Open Material Transfer Agreement, which is basically a null agreement that satisfied the lawyers at various institutes
17:25 < juul> and there is work on the BPA: BioBrick Public Agreement 2.0 which tries to be something similar to a non-copyleft style license but for the patent regime, but there are many issues with that, such as: just because someone says they're not going to enforce patents related to a thing they're publishing that doesn't mean that they didn't inadvertently violate a patent, and you likely won't know until you
17:25 < juul> receive a cease and desist (or worse)
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18:20 < streety> what does open source mean for biology? The sequence is known? At least when talking about DNA/RNA/proteins
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18:39 < juul> streety: what if the sequence is patented?
18:39 < juul> just because source code to a program is available that does not make the program open source
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19:04 < kanzure> so far there is no reliable way to opt-out of the patent system
19:04 < kanzure> because patents are not automatically granted
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20:52 < nmz787_w> i sort of don't get the whole 'metabolic load' overhead thing in some ways... like, if just feeding it more sugar or something doesn't work.. the genetic system seems obvoiusly broken (i.e. being insanely overexpressed or something, horribly regulated, pissing off CRISPR, etc)
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--- Log closed Fri Jan 27 00:00:16 2017