--- Log opened Wed Feb 01 00:00:21 2017 00:04 -!- adlai [~adlai@unaffiliated/adlai] has quit [Ping timeout: 240 seconds] 00:05 -!- sandeepkr [~Sandeepkr@103.49.155.114] has joined ##hplusroadmap 00:08 -!- adlai [~adlai@unaffiliated/adlai] has joined ##hplusroadmap 00:12 -!- Gurkenglas [~Gurkengla@dslb-188-103-065-237.188.103.pools.vodafone-ip.de] has quit [Ping timeout: 240 seconds] 00:16 -!- adlai [~adlai@unaffiliated/adlai] has quit [Ping timeout: 256 seconds] 00:17 -!- cardboard64 [~cardboard@eth-west-pareq2-46-193-0-114.wb.wifirst.net] has joined ##hplusroadmap 00:20 -!- adlai [~adlai@unaffiliated/adlai] has joined ##hplusroadmap 00:29 -!- sandeepkr [~Sandeepkr@103.49.155.114] has quit [Read error: Connection reset by peer] 00:40 -!- Ahfa [~ahfa@176.233.172.139] has quit [Quit: Leaving] 00:44 -!- hehelleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has joined ##hplusroadmap 00:47 -!- helleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has quit [Ping timeout: 245 seconds] 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[~cluckj@pool-173-49-237-221.phlapa.fios.verizon.net] has joined ##hplusroadmap 05:05 -!- Burninate [~Burn@pool-108-56-208-224.washdc.fios.verizon.net] has quit [Ping timeout: 256 seconds] 05:05 -!- nanotube [~nanotube@unaffiliated/nanotube] has quit [Ping timeout: 256 seconds] 05:06 -!- cluckj [~cluckj@pool-173-49-237-221.phlapa.fios.verizon.net] has quit [Ping timeout: 256 seconds] 05:07 -!- Cory [~Cory@unaffiliated/cory] has joined ##hplusroadmap 05:11 -!- balrog [~balrog@unaffiliated/balrog] has joined ##hplusroadmap 05:15 -!- nanotube [~nanotube@unaffiliated/nanotube] has joined ##hplusroadmap 05:29 < kanzure> yep 05:43 -!- jcluck is now known as cluckj 06:01 < kanzure> "Soft robotic sleeve supports heart function" http://stm.sciencemag.org/content/9/373/eaaf3925 06:01 -!- augur [~augur@2601:640:8001:4222:5159:de4c:dd73:c1b6] has joined ##hplusroadmap 06:04 < kanzure> may 26-30 2017 in madrid "International Longevity & Cryopreservation Summit" http://longevitycryopreservationsummit.com/ 06:06 < kanzure> interesting that brain preservation foundation and nectome and 21st century medicine are not on that list (and what about oregoncryo?) 06:16 -!- darsie [~darsie@84-113-55-42.cable.dynamic.surfer.at] has joined ##hplusroadmap 06:42 -!- hehelleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has joined ##hplusroadmap 06:44 -!- helleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has quit [Ping timeout: 240 seconds] 06:59 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 264 seconds] 07:03 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 07:06 -!- Gurkenglas [~Gurkengla@dslb-188-103-065-237.188.103.pools.vodafone-ip.de] has joined ##hplusroadmap 07:13 < kanzure> low latency switch fpga competition thing http://www.cl.cam.ac.uk/research/srg/netfpga/challenge2017/ 07:20 -!- helleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has joined ##hplusroadmap 07:22 -!- 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[~quassel@245.30.134.37.dynamic.jazztel.es] has quit [Ping timeout: 240 seconds] 08:58 < kanzure> .tw https://twitter.com/DARPA/status/826769702512889857 08:58 < yoleaux> Wanted: Concepts/tech to enable automated, rapid screening of reaction conditions across synthetic organic chemistry http://ow.ly/WoaD308xE6u https://pbs.twimg.com/media/C3lGqXfWMAIQ4o5.jpg (@DARPA) 09:29 -!- augur [~augur@2601:640:8001:4222:5159:de4c:dd73:c1b6] has quit [Remote host closed the connection] 09:59 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 10:20 -!- hehelleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has joined ##hplusroadmap 10:23 -!- helleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has quit [Ping timeout: 245 seconds] 10:23 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has joined ##hplusroadmap 10:24 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has quit [Remote host closed the connection] 10:34 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has joined ##hplusroadmap 10:34 -!- helleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has joined ##hplusroadmap 10:36 -!- hehelleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has quit [Ping timeout: 245 seconds] 10:44 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap 10:51 -!- razzy [~razzy@labka.stud.slu.cz] has quit [Remote host closed the connection] 11:15 -!- drewbot [~cinch@ec2-50-16-106-84.compute-1.amazonaws.com] has quit [Remote host closed the connection] 11:15 -!- drewbot [~cinch@ec2-54-80-220-216.compute-1.amazonaws.com] has joined ##hplusroadmap 13:04 -!- Gurkenglas [~Gurkengla@dslb-188-103-065-237.188.103.pools.vodafone-ip.de] has quit [Ping timeout: 245 seconds] 13:07 < kanzure> some stuff about censorship resistance (although i was aiming for low bandwidth security models) http://gnusha.org/bitcoin-wizards/2017-02-01.log 13:29 -!- Gurkenglas [~Gurkengla@dslb-188-103-065-237.188.103.pools.vodafone-ip.de] has joined ##hplusroadmap 13:40 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Remote host closed the connection] 13:40 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap 13:54 -!- poppingtonic1 [~brian@105.57.194.49] has joined ##hplusroadmap 13:56 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 264 seconds] 14:21 -!- poppingtonic1 [~brian@105.57.194.49] has quit [Remote host closed the connection] 14:51 -!- jtimon [~quassel@245.30.134.37.dynamic.jazztel.es] has joined ##hplusroadmap 15:00 -!- andytoshi [~apoelstra@wpsoftware.net] has quit [Ping timeout: 272 seconds] 15:01 -!- archels_ [charl@toad.stack.nl] has quit [Remote host closed the connection] 15:12 -!- hehelleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has joined ##hplusroadmap 15:15 -!- helleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has quit [Ping timeout: 245 seconds] 15:52 -!- cardboard64 [~cardboard@eth-west-pareq2-46-193-0-114.wb.wifirst.net] has quit [Quit: cardboard64] 15:54 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 16:17 -!- cluckj [~cluckj@pool-173-49-237-221.phlapa.fios.verizon.net] has joined ##hplusroadmap 16:29 < kanzure> blort 16:48 < kanzure> http://gizmodo.com/the-fda-is-cracking-down-on-rogue-genetic-engineers-1791760888 16:52 -!- Gurkenglas [~Gurkengla@dslb-188-103-065-237.188.103.pools.vodafone-ip.de] has quit [Ping timeout: 248 seconds] 16:52 < cluckj> k 16:52 < cluckj> on it 16:55 < cluckj> http://www.fda.gov/downloads/AnimalVeterinary/GuidanceComplianceEnforcement/GuidanceforIndustry/UCM113903.pdf <-- draft guidelines 16:56 < kanzure> cluckj: if you feel like being useful, how about drafting them a framework where diybiologists are given a regulatory sandbox to which they can self-subscribe 16:56 < kanzure> fda would be responsible for operating this sandbox (namely, setting up the framework and policy) allowing for the development of unapproved unregulated items as long as they conform to the guidelines of the sandbox 16:57 < cluckj> I'm not through the whole thing yet, but it appears that the journalist overstated what is going on in there 16:57 < kanzure> there is a similar concept in the financial markets at the moment, such as in singapore and hong kong 16:57 < cluckj> "investigational use" organisms seem to be largely exempt 16:57 < kanzure> https://www.finextra.com/blogposting/13055/blockchain-playing-in-the-regulatory-sandbox 16:58 < kanzure> ehh still, the FDA has a paramilitary police force and i'm sure they would be happy to setup regulations about unsanctioned gene therapy 16:59 < cluckj> yeah 17:00 < cluckj> this looks like it only applies to multicellular organisms literally in the animal kingdom 17:01 < cluckj> I'll contact the person at the FDA with my credentials and see what's up with it 17:05 < cluckj> oh that is kinda creepy how they are framing the proposed regulation 17:08 < cluckj> "animals of nonfood-producing species whose genomes have been intentionally altered that are raised and used in contained and controlled conditions such as laboratory animals with intentionally altered genomes used in research institutions. Although we generally intend to exercise enforcement discretion with regard to INAD and NADA requirements for such animals, we retain the discretion to take enforcement action if we 17:08 < cluckj> learn of safety concerns associated with them" 17:09 < cluckj> that is the exemption part that should(??????) keep them off amateurs, unless they try to sell or distribute the organisms 17:12 < kanzure> we could do a reply if they still have their comment period open 17:16 < cluckj> it's open until april 19th 2017 17:17 < cluckj> nmz787 already commented on it 17:18 -!- hehelleshin is now known as helleshin 17:52 -!- delinquentme [~delinquen@173-228-1-246.dsl.static.fusionbroadband.com] has joined ##hplusroadmap 17:54 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Remote host closed the connection] 18:36 < streety> It looks like George Church may be giving a talk here next week. Possibly having lunch with him together with some others. Anything I should ask if I get chance? 18:42 < cluckj> "you gonna finish those fries?" 18:44 < kanzure> streety: endless list of stuff to talk with that guy about, depends on your interests i guess 18:44 < kanzure> i would babble at him about directed evolution of yeast homologous recombination for dna assembly from small fragments 18:44 < kanzure> or the dna barcoding connectomics stuff 18:46 < kanzure> i would probably babble about "use azobenzene and hook up a modified polymerase to a CMOS circuit" dna synthesis stuff 18:46 < kanzure> here are many of the things i would babble about, i guess http://diyhpl.us/~bryan/irc/2017-02-03-beacon.pdf 18:50 < kanzure> if he has interesting obscure mutations for sleep or memory, that would be interesting to hear from him, on the order of http://diyhpl.us/wiki/genetic-modifications/ 18:51 < kanzure> if you just want to geek out with him then i propose memorizing http://diyhpl.us/wiki/gene-editing/ and http://diyhpl.us/wiki/dna/projects/#igem-2015 or 2016 19:19 < streety> I will read up 19:20 < streety> Always difficult to predict where the conversation will go. Only an hour though so tends to be fairly light 19:23 -!- maaku [~quassel@173-228-107-141.dsl.static.fusionbroadband.com] has quit [Quit: No Ping reply in 180 seconds.] 19:23 -!- yashgaroth [~yashgarot@2602:306:35fa:d500:f5e0:f867:a11d:8d52] has joined ##hplusroadmap 19:24 -!- maaku [~quassel@173-228-107-141.dsl.static.fusionbroadband.com] has joined ##hplusroadmap 19:26 < cluckj> kanzure, https://cgsr.llnl.gov/content/assets/docs/Independent_Biotechnology_Workshop_SummaryNOV2016.pdf seen this? 19:27 < cluckj> I'm looking through the regulatory sandbox stuff too, trying to figure out what that might look like for diy bio 19:28 < kanzure> nope. 19:29 < cluckj> it feels a little incompatible with the FDA's current regulatory regime ("stop it stop it stop it") 19:30 < cluckj> I had literally no idea that workshop even happened, or I would have gotten into it :\ 19:32 < cluckj> I wonder who went... 19:33 < cluckj> it sounds like from the kinds of responses, that it was mostly bay area biohackers and maybe someone from genspace 19:35 < kanzure> i didn't see an email to the diybio mailing list about it. 19:37 < cluckj> me neither; rob carlson and patrik were there for sure 19:39 < cluckj> and todd kuiken 19:44 -!- cluckj [~cluckj@pool-173-49-237-221.phlapa.fios.verizon.net] has quit [Ping timeout: 240 seconds] 19:46 -!- cluckj [~cluckj@pool-173-49-237-221.phlapa.fios.verizon.net] has joined ##hplusroadmap 19:48 < cluckj> kinda weird how biocurious has taken over the spotlight... 19:51 < kanzure> nah, organizations are much more legible to regulators 19:52 < kanzure> regulators don't really have the mindset for non-institutionalized folks... e.g. "let's make resources available to make sure nobody dies" rather than "let's yell at them until they buy licenses and create companies that we can more easily regulate" (which i would say is the current cultural perspective) 19:54 < kanzure> if they wanted to make a positive impact, they should create/curate educational material and facilitate public comms between private individuals 19:55 < kanzure> -- they won't, of course, because they will see education as causing more diybio to occur in the first plae (which they will find inexcusable) 19:55 < kanzure> *place 19:55 < kanzure> can be hard for others to accept that trends will continue regardless of their participation. 19:55 < kanzure> (well, for regulators.) 19:58 < cluckj> yes, I know that :P I mean how the focus has shifted from genspace to biocurious 19:58 < cluckj> but the explanation for that is kinda in what you said with the cultural perspective bit 19:58 < kanzure> oh, in that case i'll chalk it up to, they were in the area 19:58 < cluckj> hah 19:59 < cluckj> I was going to say that biocurious tends to get the vc/crowdfunded capitalist projects 19:59 < cluckj> and because money is interesting, that's where the journalists look 20:01 < cluckj> I hope I can get this research postdoc and get out to biocurious and see what's going on there with openinsulin 20:14 -!- maaku [~quassel@173-228-107-141.dsl.static.fusionbroadband.com] has quit [Ping timeout: 245 seconds] 20:14 -!- maaku [~quassel@173-228-107-141.dsl.static.fusionbroadband.com] has joined ##hplusroadmap 20:21 -!- delinquentme [~delinquen@173-228-1-246.dsl.static.fusionbroadband.com] has quit [Ping timeout: 240 seconds] 20:31 < kanzure> biopunk.pdf takedown request :( 20:41 < cluckj> ? 20:42 < kanzure> DMCA takedown request 20:43 < cluckj> wohlsen's book? 20:43 < kanzure> yes 20:43 < cluckj> :/ weak 20:46 < cluckj> maybe the better question is why isn't it open-source licensed in the first place.......... 20:48 < cluckj> penguin press, marcus owns the copyright 20:48 < kanzure> heading to michigan tomorrow, see you dorks later 20:49 < cluckj> have fun, good luck with your presentation 20:51 -!- delinquentme [~delinquen@184.250.60.184] has joined ##hplusroadmap 21:01 -!- hehelleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has joined ##hplusroadmap 21:03 -!- helleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has quit [Ping timeout: 245 seconds] 21:13 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has quit [Remote host closed the connection] 21:18 -!- delinquentme [~delinquen@184.250.60.184] has quit [Ping timeout: 256 seconds] 21:34 -!- abetusk [~abe@68.175.143.22] has quit [Ping timeout: 258 seconds] 21:35 -!- darsie [~darsie@84-113-55-42.cable.dynamic.surfer.at] has quit [Ping timeout: 264 seconds] 21:41 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 21:49 -!- jtimon [~quassel@245.30.134.37.dynamic.jazztel.es] has quit [Ping timeout: 240 seconds] 21:53 -!- abetusk [~abe@68.175.143.22] has joined ##hplusroadmap 21:53 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 256 seconds] 21:53 -!- abetusk is now known as Guest94197 21:54 -!- superobserver [~superobse@unaffiliated/superobserver] has quit [Ping timeout: 258 seconds] 22:07 -!- delinquentme [~delinquen@108-235-112-153.lightspeed.sntcca.sbcglobal.net] has joined ##hplusroadmap 22:09 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 22:12 -!- CRM114 [~urchin@unaffiliated/urchin] has quit [Ping timeout: 264 seconds] 22:12 -!- nmz787 [~nmz787@unaffiliated/nmz787] has quit [Ping timeout: 264 seconds] 22:12 -!- bsm117532 [~mcelrath@38.121.165.30] has quit [Ping timeout: 264 seconds] 22:13 -!- nmz787 [~nmz787@unaffiliated/nmz787] has joined ##hplusroadmap 22:13 -!- sivoais [~zaki@unaffiliated/sivoais] has quit [Ping timeout: 264 seconds] 22:14 -!- sivoais [~zaki@unaffiliated/sivoais] has joined ##hplusroadmap 22:26 -!- yashgaroth [~yashgarot@2602:306:35fa:d500:f5e0:f867:a11d:8d52] has quit [Quit: Leaving] 22:49 -!- maaku [~quassel@173-228-107-141.dsl.static.fusionbroadband.com] has quit [Quit: No Ping reply in 180 seconds.] 22:51 -!- maaku [~quassel@173-228-107-141.dsl.static.fusionbroadband.com] has joined ##hplusroadmap 23:31 -!- Gurkenglas [~Gurkengla@dslb-188-103-065-237.188.103.pools.vodafone-ip.de] has joined ##hplusroadmap 23:59 -!- delinquentme [~delinquen@108-235-112-153.lightspeed.sntcca.sbcglobal.net] has quit [Ping timeout: 276 seconds] --- Log closed Thu Feb 02 00:00:22 2017