--- Log opened Wed Feb 08 00:00:27 2017 00:04 -!- ebowden [~ebowden@2001:8003:1195:de00:8162:9bcb:99a3:f71a] has joined ##hplusroadmap 00:04 -!- ebowden [~ebowden@2001:8003:1195:de00:8162:9bcb:99a3:f71a] has quit [Changing host] 00:04 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 00:07 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 252 seconds] 00:20 < archels> superkuh: heh, was just going to paste that 00:23 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 00:40 -!- sandeepkr [~Sandeepkr@103.49.155.114] has quit [Remote host closed the connection] 00:50 -!- eb3c90 [~kvirc@host86-184-170-176.range86-184.btcentralplus.com] has joined ##hplusroadmap 00:52 -!- ExeciN [ExeciN@bnc.stormbit.net] has quit [Excess Flood] 00:53 -!- augur [~augur@2601:640:8001:4222:5ae:3b47:a21a:5143] has quit [Remote host closed the connection] 00:58 -!- eb3c90 [~kvirc@host86-184-170-176.range86-184.btcentralplus.com] has quit 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##hplusroadmap 03:31 < archels> Just to give a little intuition for exactly how fast your CPU runs (assuming ~3 GHz), a single cycle takes about as much time as it takes a photon to travel from your monitor to your eyeball. 03:32 -!- sandeepkr [~Sandeepkr@103.49.155.114] has joined ##hplusroadmap 03:34 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 03:41 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Remote host closed the connection] 03:54 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap 03:56 < CRM114> archels: this really puts into perspective how slow a lot of software written in Java is 03:56 < CRM114> ;) 04:14 < archels> haha 04:49 -!- c0rw1n [~c0rw1n@ptr-178-50-80-209.dyn.mobistar.be] has joined ##hplusroadmap 05:08 -!- aedla [~quassel@c21-76.uvn.zone.eu] has quit [Ping timeout: 240 seconds] 05:16 -!- aedla [~quassel@c21-76.uvn.zone.eu] has joined ##hplusroadmap 05:19 -!- aedla [~quassel@c21-76.uvn.zone.eu] has quit [Remote host closed the connection] 05:19 -!- aedla [~quassel@c21-76.uvn.zone.eu] has joined ##hplusroadmap 05:26 -!- CRM114 [~urchin@unaffiliated/urchin] has quit [Ping timeout: 255 seconds] 05:42 -!- CRM114 [~urchin@unaffiliated/urchin] has joined ##hplusroadmap 05:42 -!- Gurkenglas [~Gurkengla@dslb-188-103-065-237.188.103.pools.vodafone-ip.de] has quit [Ping timeout: 264 seconds] 06:02 -!- Urchin [~urchin@unaffiliated/urchin] has joined ##hplusroadmap 06:19 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Read error: Connection reset by peer] 06:20 -!- ebowden [~ebowden@2001:8003:103c:ee00:78e5:c80b:6b96:7ce2] has joined ##hplusroadmap 06:20 -!- ebowden [~ebowden@2001:8003:103c:ee00:78e5:c80b:6b96:7ce2] has quit [Changing host] 06:20 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 06:41 < kanzure> 09309fjdqf90rfdafdaolohugv 06:46 < JayDugger> OTS timestamp, muscle spasm, or dropped keyboard? 06:48 < kanzure> brain tumor 07:14 -!- juri__ is now known as juri_ 07:16 < juri_> so, my new number cruncher box is online. 32 cores, 256G of ram. 07:18 < chris_99> fancy :) what processor(s) is that? 07:21 -!- CheckDavid [uid14990@gateway/web/irccloud.com/x-vvlppgneryffiesg] has joined ##hplusroadmap 07:23 < juri_> amd 6367. 07:23 < juri_> two sockets, both populated. 07:23 < chris_99> ah cool 07:23 < chris_99> is that ddr3 or 4? 07:23 < juri_> 3e 07:25 < juri_> have haskell, have implicitcad. will grind for the future of humanity. ;) 07:26 < juri_> we just got a vacuum sensor for our SEM. now, to mount it, and test the vacuum quality in the machine. 07:36 < rkos> what do yall think about benjamin bratton 07:37 < chris_99> juri_, cool, have you got images from it? 08:02 -!- Gurkenglas [~Gurkengla@dslb-188-103-065-237.188.103.pools.vodafone-ip.de] has joined ##hplusroadmap 08:13 < juri_> not yet. just started crunching. 08:13 < juri_> oh, the sem. no, we're still reconditioning. 08:14 < chris_99> ahh 08:19 -!- augur [~augur@2601:640:8001:4222:5ae:3b47:a21a:5143] has joined ##hplusroadmap 08:19 -!- augur [~augur@2601:640:8001:4222:5ae:3b47:a21a:5143] has quit [Remote host closed the connection] 08:19 -!- Guest61445 [~augur@2601:640:8001:4222:5ae:3b47:a21a:5143] has joined ##hplusroadmap 08:29 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 260 seconds] 08:42 -!- c0rw1n [~c0rw1n@ptr-178-50-80-209.dyn.mobistar.be] has quit [Ping timeout: 240 seconds] 08:45 -!- jtimon [~quassel@245.30.134.37.dynamic.jazztel.es] has joined ##hplusroadmap 09:08 -!- darsie [~darsie@84-113-55-42.cable.dynamic.surfer.at] has joined ##hplusroadmap 09:14 -!- Gurkenglas_ [~Gurkengla@dslb-178-005-218-116.178.005.pools.vodafone-ip.de] has joined ##hplusroadmap 09:16 -!- Gurkenglas [~Gurkengla@dslb-188-103-065-237.188.103.pools.vodafone-ip.de] has quit [Ping timeout: 240 seconds] 10:03 < heath> juri_: if you ever get one of these, i'll gladly accept ssh access :) https://www.cavium.com/newsevents-GIGABYTE-announces-384-Core-2U-server-powered-by-Cavium-ThunderX-ARMv8-processors.html 10:06 -!- fleshtheworld [~fleshthew@2602:306:cf0f:4c20:f974:ce40:bf23:99a7] has joined ##hplusroadmap 10:28 -!- nmz787_w [~ntmccork@134.134.137.73] has joined ##hplusroadmap 10:28 -!- c0rw1n [~c0rw1n@91.181.4.198] has joined ##hplusroadmap 10:29 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Read error: Connection reset by peer] 10:30 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 10:30 < nmz787_w> chris_99: I just read about these https://en.wikipedia.org/wiki/Lecher_lines and was thinking it might be a cool image if you watched some traces in the Electron Microscope... might be some really cool visualization... like if the lines had audio running through or something 10:31 < chris_99> oh i saw that post on had about them, but yeah heh that'd be very interesting 10:31 < nmz787_w> yeah that's what I was reading 10:32 < nmz787_w> since the microscope scans an image, I guess it would be blurred unless the waves were standing while you imaged 10:34 < chris_99> ah hmm 10:35 -!- strages [sid11297@gateway/web/irccloud.com/x-abhhzkndgrzbffhj] has quit [Remote host closed the connection] 10:35 -!- EnabrinTain [sid11525@gateway/web/irccloud.com/x-wyannuaxkrfjmfwr] has quit [Remote host closed the connection] 10:35 < chris_99> http://forensic.to/ENF%20processed.pdf thought this is cool, might have a play with implementing it 10:35 -!- nickjohnson [sid789@gateway/web/irccloud.com/x-cwakpwtdanmwyvqk] has quit [Remote host closed the connection] 10:37 -!- CheckDavid [uid14990@gateway/web/irccloud.com/x-vvlppgneryffiesg] has quit [Remote host closed the connection] 10:43 -!- Guest61445 is now known as augur 10:43 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 10:45 -!- wrldpcmbl [sid145438@gateway/web/irccloud.com/x-wayctluszdtjrirg] has quit [Remote host closed the connection] 11:06 -!- nmz787_w1 [~ntmccork@134.134.139.76] has joined ##hplusroadmap 11:08 -!- nmz787_w2 [~ntmccork@134.134.139.76] has joined ##hplusroadmap 11:08 -!- nmz787_w1 [~ntmccork@134.134.139.76] has quit [Remote host closed the connection] 11:08 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 276 seconds] 11:08 -!- eb3c90 [~kvirc@host86-184-170-176.range86-184.btcentralplus.com] has joined ##hplusroadmap 11:08 -!- nmz787_w [~ntmccork@134.134.137.73] has quit [Remote host closed the connection] 11:18 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 11:21 -!- nickjohnson [sid789@gateway/web/irccloud.com/x-djgbmdjlyouflrsx] has joined ##hplusroadmap 11:24 -!- CheckDavid [uid14990@gateway/web/irccloud.com/x-svmeneqhzuspmyyb] has joined ##hplusroadmap 11:25 -!- hehelleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has joined ##hplusroadmap 11:27 -!- strages [sid11297@gateway/web/irccloud.com/x-sulytehbtwjcoeph] has joined ##hplusroadmap 11:27 < eb3c90> I've got a concept I would like to find writings about (if they exist). I have the idea of a measuring the size of a terrarium civilisation. A terrarium civilisation is basically a technological human civilisation that can run on just resources it has and the sunlight coming into it. 11:27 -!- EnabrinTain [sid11525@gateway/web/irccloud.com/x-kqxynsdmgfhqwibf] has joined ##hplusroadmap 11:28 < eb3c90> Currently the size of our terrarium civilisation is the entire earth, I think it would be good to shrink it. 11:28 < eb3c90> ^ do such writings exist 11:29 -!- Guest22271 [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has quit [Ping timeout: 245 seconds] 11:35 -!- CheckDavid [uid14990@gateway/web/irccloud.com/x-svmeneqhzuspmyyb] has quit [Remote host closed the connection] 11:39 -!- Gurkenglas_ [~Gurkengla@dslb-178-005-218-116.178.005.pools.vodafone-ip.de] has quit [Ping timeout: 252 seconds] 11:43 < Urchin> eb3c90: are you looking for something along the lines of a natural experiment? 11:43 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Quit: Leaving] 11:44 -!- CheckDavid [uid14990@gateway/web/irccloud.com/x-wsjhqwsgwprosdvy] has joined ##hplusroadmap 11:48 < eb3c90> Urchin: Hmm, I'm not quite sure If I'm getting where you are coming from. I shall try and explain, there are lots of measures of humanity technology in terms of size (e.g. Kardashev scale) I was wondering if there were measurements in terms of our resiliency and dispersability. 11:49 < Urchin> eb3c90: I don't think there is 11:50 < Urchin> eb3c90: the closest thing I can think of would basically be remnants of failed civilizations that reached perfect equilibrium with the local ecosystems and ludditism passed on as sage wisdom 11:51 < Urchin> eb3c90: I suppose such societies keep working because they're at rock bottom and staying there 11:54 < kanzure> eb3c90: http://www.molecularassembler.com/KSRM.htm 11:57 < eb3c90> Kanzure: Yeah nano-tech is definitely near the end-game of that development path. I'm wondering whether we will have a phase of microfactories/micro-recyclers first, when they are both no longer constrained to be human scale so they can be fixed/observed by their human maintainers. 11:57 -!- wrldpcmbl [sid145438@gateway/web/irccloud.com/x-hzszhtztofdhpolq] has joined ##hplusroadmap 11:58 < kanzure> no i don't mean nanotech, look at the page 11:59 < eb3c90> Kanzure: Ah cool. I saw merkle and freitas, molecularassembler and auto-completed. 11:59 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap 12:22 < poppingtonic> Self-replicating machines of this kind would definitely make civilisation extremely resilient, if the resultant sub-communities had good co-ordination mechanisms and at least tried to avoid warlike Nash equilibria. 12:23 -!- nmz787_w2 [~ntmccork@134.134.139.76] has quit [Ping timeout: 252 seconds] 12:23 < poppingtonic> Imagine every few hundred miles there was a MIT Centre for Bits and Atoms, or a Noisebridge. 12:27 -!- nmz787_w [~ntmccork@134.134.137.73] has joined ##hplusroadmap 12:28 -!- eb3c90 [~kvirc@host86-184-170-176.range86-184.btcentralplus.com] has quit [Ping timeout: 240 seconds] 12:43 -!- Gurkenglas_ [~Gurkengla@dslb-178-005-218-116.178.005.pools.vodafone-ip.de] has joined ##hplusroadmap 12:54 -!- Zer0_cool [~Zer0_cool@162.216.46.184] has joined ##hplusroadmap 12:54 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Quit: Leaving.] 12:54 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 12:56 -!- augur [~augur@2601:640:8001:4222:5ae:3b47:a21a:5143] has quit [Remote host closed the connection] 13:22 -!- augur [~augur@208.66.31.98] has joined ##hplusroadmap 13:23 -!- ebowden_ [~ebowden@2001:8003:103c:ee00:1534:6851:12b0:dd88] has joined ##hplusroadmap 13:23 -!- ebowden_ [~ebowden@2001:8003:103c:ee00:1534:6851:12b0:dd88] has quit [Changing host] 13:23 -!- ebowden_ [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 13:24 -!- augur_ [~augur@noisebridge130.static.monkeybrains.net] has joined ##hplusroadmap 13:24 -!- augur_ [~augur@noisebridge130.static.monkeybrains.net] has quit [Remote host closed the connection] 13:26 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Ping timeout: 240 seconds] 13:26 -!- augur [~augur@208.66.31.98] has quit [Ping timeout: 240 seconds] 13:34 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has joined ##hplusroadmap 13:45 -!- eb3c90 [~kvirc@host86-184-170-176.range86-184.btcentralplus.com] has joined ##hplusroadmap 13:50 < heath> .title https://www.youtube.com/watch?v=h0962biiZa4 13:50 < yoleaux> Superintelligence: Science or Fiction? | Elon Musk & Other Great Minds - YouTube 13:53 < heath> "Elon Musk, Stuart Russell, Ray Kurzweil, Demis Hassabis, Sam Harris, Nick Bostrom, David Chalmers, Bart Selman, and Jaan Tallinn discuss with Max Tegmark (moderator) what likely outcomes might be if we succeed in building human-level AGI, and also what we would like to happen." 13:54 -!- CheckDavid [uid14990@gateway/web/irccloud.com/x-wsjhqwsgwprosdvy] has quit [Quit: Connection closed for inactivity] 14:00 < poppingtonic> From KSRM, p. 13: ''An amusing example: 'In the reformatory at Caserta, Italy, as guards watched a movie, five youthful prisoners escaped. The movie the guards were watching was about guards who watched a movie while youthful prisoners escaped.' '' 14:03 -!- ebowden_ [~ebowden@unaffiliated/ebowden] has quit [Remote host closed the connection] 14:09 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Quit: Leaving] 14:15 -!- Gurkenglas_ [~Gurkengla@dslb-178-005-218-116.178.005.pools.vodafone-ip.de] has quit [Ping timeout: 260 seconds] 14:15 -!- delinquentme [~delinquen@184.250.42.225] has joined ##hplusroadmap 14:16 < delinquentme> is there something like google scholar for india? 14:16 < delinquentme> Ive got a few researchers who seem to not even exist 14:18 -!- ebowden [~ebowden@CPE-101-180-233-178.lnse3.cha.bigpond.net.au] has joined ##hplusroadmap 14:18 -!- ebowden [~ebowden@CPE-101-180-233-178.lnse3.cha.bigpond.net.au] has quit [Changing host] 14:18 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 14:34 -!- ekr [~ekr@unaffiliated/ekr] has joined ##hplusroadmap 14:36 -!- drewbot [~cinch@ec2-54-226-108-27.compute-1.amazonaws.com] has quit [Remote host closed the connection] 14:36 -!- drewbot [~cinch@ec2-54-224-18-155.compute-1.amazonaws.com] has joined ##hplusroadmap 14:40 -!- eb3c90 [~kvirc@host86-184-170-176.range86-184.btcentralplus.com] has quit [Ping timeout: 240 seconds] 14:43 -!- jenelizabeth [~jenelizab@cpc76810-brmb10-2-0-cust4.1-3.cable.virginm.net] has quit [Ping timeout: 258 seconds] 14:50 < juri_> heath: good luck. ;P 14:55 -!- sosiles_ [495d8f6a@gateway/web/freenode/ip.73.93.143.106] has joined ##hplusroadmap 14:59 < nmz787_w> delinquentme: they probably all use whatsap 14:59 < nmz787_w> or whatsapp 15:03 -!- Gurkenglas_ [~Gurkengla@dslb-178-005-218-116.178.005.pools.vodafone-ip.de] has joined ##hplusroadmap 15:03 -!- sosiles_ [495d8f6a@gateway/web/freenode/ip.73.93.143.106] has quit [Ping timeout: 260 seconds] 15:21 < kanzure> or researchgate/academia.edu 15:22 < kanzure> .wik nicergoline 15:22 < yoleaux> "Nicergoline (INN, marketed under the trade name Sermion) is an ergot derivative used to treat senile dementia and other disorders with vascular origins. It decreases vascular resistance and increases arterial blood flow in the brain, improving the utilization of oxygen and glucose by brain cells." -- https://en.wikipedia.org/wiki/Nicergoline 15:23 < kanzure> .wik sulbutiamine 15:23 < yoleaux> "Sulbutiamine (brand name: Arcalion) is a synthetic derivative of thiamine (vitamin B1). As a dimer of two modified thiamine molecules, it is a lipophilic compound that crosses the blood-brain barrier more readily than thiamine and increases the levels of thiamine and thiamine phosphate esters in the brain." -- https://en.wikipedia.org/wiki/Sulbutiamine 15:31 -!- delinquentme [~delinquen@184.250.42.225] has quit [Ping timeout: 255 seconds] 15:51 -!- jenelizabeth [~jenelizab@cpc76810-brmb10-2-0-cust4.1-3.cable.virginm.net] has joined ##hplusroadmap 16:06 -!- pompolic [~A@unaffiliated/pompolic] has quit [Ping timeout: 252 seconds] 16:08 -!- pompolic [~A@unaffiliated/pompolic] has joined ##hplusroadmap 16:37 -!- cynsia [cyn@2600:3c03::f03c:91ff:fe79:d5d] has joined ##hplusroadmap 16:39 -!- cynsia_ [cyn@2600:3c03::f03c:91ff:fe79:d5d] has joined ##hplusroadmap 16:42 -!- cynsia [cyn@2600:3c03::f03c:91ff:fe79:d5d] has quit [Ping timeout: 255 seconds] 16:56 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Remote host closed the connection] 16:56 -!- hehelleshin is now known as helleshin 17:02 -!- ebowden [~ebowden@2001:8003:103c:ee00:8164:fa74:dff:8f5d] has joined ##hplusroadmap 17:02 -!- ebowden [~ebowden@2001:8003:103c:ee00:8164:fa74:dff:8f5d] has quit [Changing host] 17:02 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 17:06 -!- CRM114 [~urchin@unaffiliated/urchin] has quit [Ping timeout: 240 seconds] 17:07 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Remote host closed the connection] 17:08 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 17:13 -!- Zer0_cool [~Zer0_cool@162.216.46.184] has quit [Quit: Leaving] 17:18 -!- Urchin [~urchin@unaffiliated/urchin] has quit [Ping timeout: 255 seconds] 17:18 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Remote host closed the connection] 17:19 -!- Urchin [~urchin@89.17.16.190] has joined ##hplusroadmap 17:19 -!- Gurkenglas_ [~Gurkengla@dslb-178-005-218-116.178.005.pools.vodafone-ip.de] has quit [Ping timeout: 240 seconds] 17:22 < kanzure> blort 17:23 -!- ebowden [~ebowden@2001:8003:103c:ee00:3099:67cb:6faf:6dba] has joined ##hplusroadmap 17:23 -!- ebowden [~ebowden@2001:8003:103c:ee00:3099:67cb:6faf:6dba] has quit [Changing host] 17:23 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 17:25 -!- cynsia [cyn@2600:3c03::f03c:91ff:fe79:d5d] has joined ##hplusroadmap 17:25 < nmz787_w> zingadoodle 17:26 < nmz787_w> my buddy said he tried that sulbutiamine 17:26 < nmz787_w> said he took it coincident with choline and other nootropics... so hard to say where the benefit came from, but he said he seemed to notice a positive effect 17:26 -!- cynsia_ [cyn@2600:3c03::f03c:91ff:fe79:d5d] has quit [Ping timeout: 255 seconds] 17:30 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Remote host closed the connection] 17:30 -!- q4 [~q4@user-94-254-234-131.play-internet.pl] has joined ##hplusroadmap 17:32 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 17:37 -!- Gurkenglas_ [~Gurkengla@dslb-178-005-218-116.178.005.pools.vodafone-ip.de] has joined ##hplusroadmap 18:01 -!- yashgaroth [~yashgarot@2602:306:35fa:d500:f5e0:f867:a11d:8d52] has joined ##hplusroadmap 18:15 -!- nmz787_w1 [~ntmccork@134.134.139.77] has joined ##hplusroadmap 18:15 -!- nmz787_w1 [~ntmccork@134.134.139.77] has quit [Client Quit] 18:16 -!- nmz787_w [~ntmccork@134.134.137.73] has quit [Remote host closed the connection] 18:22 -!- Gurkenglas_ [~Gurkengla@dslb-178-005-218-116.178.005.pools.vodafone-ip.de] has quit [Ping timeout: 240 seconds] 18:27 -!- cynsia [cyn@2600:3c03::f03c:91ff:fe79:d5d] has quit [Quit: Leaving] 18:35 < kanzure> .tw https://twitter.com/DARPA/status/829025272846508033 18:35 < yoleaux> Proposers Days for new Pandemic Prevention Platform coming up fast. McLean, VA: Feb 22; San Diego: Mar 2. http://ow.ly/1YEe308LYwI #medicine https://pbs.twimg.com/media/C4FKFxgWIAYuWjh.jpg (@DARPA) 19:00 -!- superkuh [~superkuh@unaffiliated/superkuh] has quit [Ping timeout: 252 seconds] 19:06 < kanzure> "Light controls cerebral blood flow in naive animals" http://www.nature.com/articles/ncomms14191 https://twitter.com/anna_beyeler/status/826896510541504513 19:07 < kanzure> "Here we test whether light stimulation protocols similar to those commonly used in opto-fMRI or to study neurovascular coupling modulate blood flow in mice that do not express light sensitive proteins. Combining two-photon laser scanning microscopy and ultrafast functional ultrasound imaging, we report that in the naive mouse brain, light per se causes a calcium decrease in arteriolar smooth ... 19:07 < kanzure> ...muscle cells, leading to pronounced vasodilation, without excitation of neurons and astrocytes. This photodilation is reversible, reproducible and energy-dependent, appearing at about 0.5 mJ." 19:10 < kanzure> "Genetic defects in ?-spectrin and tau sensitize C. elegans axons to movement-induced damage via torque-tension coupling" https://elifesciences.org/content/6/e20172 19:10 < kanzure> "Here, we investigated the question of how the neuronal cytoskeleton protects axons and dendrites from mechanical stress, exploiting mutations in UNC-70 ?-spectrin, PTL-1 tau/MAP2-like and MEC-7 ?-tubulin proteins in Caenorhabditis elegans. We found that mechanical stress induces supercoils and plectonemes in the sensory axons of spectrin and tau double mutants. Biophysical measurements, sup... 19:10 < kanzure> ...er-resolution, and electron microscopy, as well as numerical simulations of neurons as discrete, elastic rods provide evidence that a balance of torque, tension, and elasticity stabilizes neurons against mechanical deformation. We conclude that the spectrin and microtubule cytoskeletons work in combination to protect axons and dendrites from mechanical stress and propose that defects in ?-spe... 19:10 < kanzure> ...ctrin and tau may sensitize neurons to damage." 19:10 < kanzure> "High-resolution imaging of cellular dopamine efflux using a fluorescent nanosensor array" http://www.pnas.org/content/early/2017/02/07/1613541114.abstract 19:11 < kanzure> .title https://www.youtube.com/watch?v=zvS71CdNUsg 19:11 < yoleaux> Ben Barres: What do reactive astrocytes do? - YouTube 19:12 -!- superkuh [~superkuh@unaffiliated/superkuh] has joined ##hplusroadmap 19:28 -!- jtimon [~quassel@245.30.134.37.dynamic.jazztel.es] has quit [Ping timeout: 264 seconds] 20:01 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Quit: Leaving.] 20:39 -!- q4 [~q4@user-94-254-234-131.play-internet.pl] has quit [Ping timeout: 258 seconds] 21:40 -!- darsie [~darsie@84-113-55-42.cable.dynamic.surfer.at] has quit [Ping timeout: 260 seconds] 21:42 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 21:50 -!- nmz787_w [~ntmccork@134.134.139.74] has joined ##hplusroadmap 22:05 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 256 seconds] 22:07 -!- fleshtheworld [~fleshthew@2602:306:cf0f:4c20:f974:ce40:bf23:99a7] has quit [Quit: Leaving] 22:21 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 22:29 -!- drewbot_ [~cinch@ec2-54-224-18-155.compute-1.amazonaws.com] has joined ##hplusroadmap 22:33 -!- drewbot [~cinch@ec2-54-224-18-155.compute-1.amazonaws.com] has quit [Ping timeout: 240 seconds] 22:33 -!- sachy [~sachy@2001:67c:2190:c0de:da50:e6ff:feed:cf14] has quit [Ping timeout: 240 seconds] 22:33 -!- Aurelius [~cpopell@50.35.79.117] has quit [Ping timeout: 240 seconds] 22:33 -!- sachy [~sachy@2001:67c:2190:c0de:da50:e6ff:feed:cf14] has joined ##hplusroadmap 22:37 -!- Aurelius [~cpopell@50.35.79.117] has joined ##hplusroadmap 22:39 -!- abetusk [~abe@68.175.143.22] has quit [Ping timeout: 276 seconds] 22:40 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 258 seconds] 22:50 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has quit [Remote host closed the connection] 22:52 -!- esmerelda [~mabel@2601:602:9603:a3f8:626d:c7ff:fe5f:86c7] has joined ##hplusroadmap 22:55 -!- poppingtonic [~brian@197.237.34.154] has joined ##hplusroadmap 22:55 -!- poppingtonic [~brian@197.237.34.154] has quit [Changing host] 22:55 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 22:59 -!- yashgaroth [~yashgarot@2602:306:35fa:d500:f5e0:f867:a11d:8d52] has quit [Quit: Leaving] 23:00 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 240 seconds] 23:00 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 23:13 -!- abetusk [~abe@68.175.143.22] has joined ##hplusroadmap 23:14 -!- abetusk is now known as Guest52475 23:37 -!- sandeepkr [~Sandeepkr@103.49.155.114] has quit [Read error: Connection reset by peer] 23:41 -!- augur [~augur@2601:640:8001:4222:54c0:38ee:3eab:f34a] has joined ##hplusroadmap --- Log closed Thu Feb 09 00:00:28 2017