--- Log opened Fri Feb 17 00:00:35 2017 00:00 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has quit [Remote host closed the connection] 00:25 -!- augur [~augur@2601:645:8300:2b03:708e:6491:ba2e:8388] has joined ##hplusroadmap 01:03 < JayDugger> Thanks, kanzure. Another Japanese pop song stuck in my head. 01:18 -!- augur [~augur@2601:645:8300:2b03:708e:6491:ba2e:8388] has quit [Read error: Connection reset by peer] 01:19 -!- augur [~augur@2601:645:8300:2b03:708e:6491:ba2e:8388] has joined ##hplusroadmap 01:38 -!- Jenda` [~bablbam@dekatron.hrach.eu] has quit [Ping timeout: 240 seconds] 01:48 -!- thxffo [~thxffo@ircbouncehouse.com] has quit [Quit: piece] 01:56 -!- nmz787_w [ntmccork@nat/intel/x-ihjmzrxecahszzuc] has quit [Quit: Leaving.] 01:59 -!- thxffo [smdikus@ircbouncehouse.com] has joined ##hplusroadmap 02:02 -!- augur_ [~augur@2601:645:8300:2b03:115f:7f12:26c1:160f] has joined ##hplusroadmap 02:06 -!- augur [~augur@2601:645:8300:2b03:708e:6491:ba2e:8388] has quit [Ping timeout: 240 seconds] 02:08 -!- urchin_ [~urchin@89.17.4.251] has quit [Changing host] 02:08 -!- urchin_ [~urchin@unaffiliated/urchin] has joined ##hplusroadmap 02:08 -!- urchin_ is now known as Urchin 02:21 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 260 seconds] 02:24 < archels> https://groups.google.com/forum/#!topic/diybio/l97VjQLls0A 02:51 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 03:01 -!- Gurkenglas [~Gurkengla@dslb-178-005-218-116.178.005.pools.vodafone-ip.de] has joined ##hplusroadmap 03:04 < archels> oops, ignore 03:05 < archels> nmz787_: 'k, the discussion makes sense now that I've read the thread. agree that he seems to be pushing his own politics 03:05 < archels> and, most critically, telling us what to do and think 03:14 -!- augur_ [~augur@2601:645:8300:2b03:115f:7f12:26c1:160f] has quit [Remote host closed the connection] 04:23 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap 04:52 < kanzure> bloop 05:02 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 240 seconds] 05:13 < JayDugger> belated bleep, now in the correct channel 05:14 -!- thxffo [smdikus@ircbouncehouse.com] has quit [Quit: piece] 05:17 -!- Jenda` [~bablbam@dekatron.hrach.eu] has joined ##hplusroadmap 05:25 -!- CRM114 [~urchin@unaffiliated/urchin] has joined ##hplusroadmap 05:28 -!- thxffo [smdikus@ircbouncehouse.com] has joined ##hplusroadmap 05:31 -!- thxffo [smdikus@ircbouncehouse.com] has quit [Client Quit] 05:41 -!- thxffo [smdikus@ircbouncehouse.com] has joined ##hplusroadmap 06:32 < kanzure> https://www.reddit.com/r/Bitcoin/comments/5ukz58/segwit_is_a_softfork_to_miners_without_supporting/[ 06:42 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Quit: Leaving] 06:52 < kanzure> .title http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.2001624 06:52 < yoleaux> Lifemap: Exploring the Entire Tree of Life 06:59 -!- redlegion[m] [redlegionm@gateway/shell/matrix.org/x-gpjzjbtbmykfjfzu] has joined ##hplusroadmap 07:09 -!- jtimon [~quassel@245.30.134.37.dynamic.jazztel.es] has joined ##hplusroadmap 07:35 -!- Douhet [~Douhet@unaffiliated/douhet] has quit [Read error: Connection reset by peer] 07:35 -!- Douhet [~Douhet@unaffiliated/douhet] has joined ##hplusroadmap 07:47 < JayDugger> Hmm...I think there exists an Android app that shows the tree of life in that paper. 07:48 < JayDugger> Yeah, right there in the paper, along with a general tree browser, looks like. Have to read this one in detail. 07:50 < JayDugger> Repository here https://github.com/damiendevienne/Lifemap 07:56 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap 08:15 < redlegion[m]> JayDugger, that's awesome. This channel is one of my favorite to lurk. 08:39 -!- nmz787_w [~ntmccork@134.134.139.76] has joined ##hplusroadmap 09:13 -!- rkos_ [rkos@228.ip-176-31-189.eu] has quit [Ping timeout: 240 seconds] 09:34 -!- Gurkenglas [~Gurkengla@dslb-178-005-218-116.178.005.pools.vodafone-ip.de] has quit [Ping timeout: 240 seconds] 09:48 -!- Gurkenglas [~Gurkengla@dslb-178-005-218-116.178.005.pools.vodafone-ip.de] has joined ##hplusroadmap 09:49 -!- thxffo [smdikus@ircbouncehouse.com] has quit [Quit: piece] 10:00 -!- thxffo [smdikus@ircbouncehouse.com] has joined ##hplusroadmap 10:03 -!- thxffo [smdikus@ircbouncehouse.com] has quit [Client Quit] 10:10 -!- jtimon [~quassel@245.30.134.37.dynamic.jazztel.es] has quit [Ping timeout: 260 seconds] 10:15 -!- thxffo [smdikus@ircbouncehouse.com] has joined ##hplusroadmap 10:33 -!- nmz787_w [~ntmccork@134.134.139.76] has quit [Quit: Leaving.] 10:40 -!- jtimon [~quassel@245.30.134.37.dynamic.jazztel.es] has joined ##hplusroadmap 10:45 -!- jtimon [~quassel@245.30.134.37.dynamic.jazztel.es] has quit [Ping timeout: 240 seconds] 10:59 -!- nmz787_w [ntmccork@nat/intel/x-ovmgyicbztzfqnjd] has joined ##hplusroadmap 11:02 -!- nmz787_w1 [~ntmccork@134.134.139.82] has joined ##hplusroadmap 11:04 -!- nmz787_w [ntmccork@nat/intel/x-ovmgyicbztzfqnjd] has quit [Ping timeout: 260 seconds] 11:12 < JayDugger> The Android app looked better in the Play Store than on my phone. YMMV. 11:24 -!- augur [~augur@2601:645:8300:2b03:115f:7f12:26c1:160f] has joined ##hplusroadmap 11:54 -!- darsie [~darsie@84-113-55-42.cable.dynamic.surfer.at] has quit [Ping timeout: 240 seconds] 12:39 -!- augur [~augur@2601:645:8300:2b03:115f:7f12:26c1:160f] has quit [Remote host closed the connection] 12:55 < nmz787_w1> "Regardless of boxing or not, these are not to be used outdoors or near any wet floor or around any fuel/flame since they could be a source of ignition." -- Now I can't help myself from thinking of ways to combine programmable HV and flames/ignition. 13:09 -!- TinKode [~TinKode@unaffiliated/tinkode] has joined ##hplusroadmap 13:12 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 13:44 -!- augur [~augur@162.217.73.146] has joined ##hplusroadmap 13:48 -!- augur [~augur@162.217.73.146] has quit [Ping timeout: 255 seconds] 13:54 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has joined ##hplusroadmap 14:10 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Quit: Leaving] 14:14 -!- helleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has joined ##hplusroadmap 14:15 -!- bsm117532 [~mcelrath@38.121.165.30] has quit [Ping timeout: 264 seconds] 14:16 -!- hehelleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has quit [Ping timeout: 240 seconds] 14:20 -!- eb3c90 [~kvirc@host81-147-141-244.range81-147.btcentralplus.com] has joined ##hplusroadmap 15:05 -!- jtimon [~quassel@245.30.134.37.dynamic.jazztel.es] has joined ##hplusroadmap 15:31 -!- eb3c90 [~kvirc@host81-147-141-244.range81-147.btcentralplus.com] has quit [Ping timeout: 268 seconds] 15:32 -!- eb3c90 [~kvirc@host81-147-141-244.range81-147.btcentralplus.com] has joined ##hplusroadmap 15:34 -!- nmz787_w [ntmccork@nat/intel/x-prkwyiidkrcqsafx] has joined ##hplusroadmap 15:37 -!- nmz787_w1 [~ntmccork@134.134.139.82] has quit [Ping timeout: 240 seconds] 15:51 -!- superobserver [~superobse@unaffiliated/superobserver] has quit [Ping timeout: 260 seconds] 15:58 -!- eb3c90 [~kvirc@host81-147-141-244.range81-147.btcentralplus.com] has quit [Ping timeout: 260 seconds] 16:21 < kanzure> jer0u93r0fa0ftefaw 16:48 -!- TinKode [~TinKode@unaffiliated/tinkode] has quit [Read error: Connection reset by peer] 16:49 -!- nmz787_w [ntmccork@nat/intel/x-prkwyiidkrcqsafx] has quit [Quit: Leaving.] 16:50 < kanzure> "MRI measurements of reporter-mediated increases in transmembrane water exchange enable detection of a gene reporter" http://www.nature.com/nbt/journal/v35/n1/full/nbt.3714.html 16:53 < kanzure> "Generating natural language inference chains" https://arxiv.org/abs/1606.01404 16:54 < kanzure> "Harnessing optogenetics to probe sub-cellular mechanics" http://biorxiv.org/content/early/2017/02/17/109595 16:55 < kanzure> "Whole exome sequencing reveals a mutation in ARMC9 as a cause of mental retardation, ptosis and polydactyly" http://biorxiv.org/content/early/2017/02/17/109124 16:56 < kanzure> "Toxicity and applications of internalised magnetite nanoparticles within live Paramecium caudatum cells" http://biorxiv.org/content/early/2017/02/17/109488 16:58 < kanzure> "Control of cerebral ischemia with magnetic nanoparticles" http://www.nature.com/nmeth/journal/v14/n2/full/nmeth.4105.html 16:58 < kanzure> "... We developed a technology that uses micromagnets to induce aggregation of magnetic nanoparticles to reversibly occlude blood flow in microvessels. This allowed induction of ischemia in a specific cortical region of conscious mice of any postnatal age, including perinatal and neonatal stages, with precise spatiotemporal control but without surgical intervention of the skull or artery." 17:27 -!- yashgaroth [~yashgarot@2602:306:35fa:d500:f5e0:f867:a11d:8d52] has joined ##hplusroadmap 17:29 -!- eudoxia [~eudoxia@r186-48-29-50.dialup.adsl.anteldata.net.uy] has joined ##hplusroadmap 17:32 < kanzure> .tw https://twitter.com/CurrentBiology/status/832389514760904704 17:32 < yoleaux> to allow big gulps, #whale nerves need to be highly extensible, here's how they are packaged http://www.cell.com/current-biology/fulltext/S0960-9822(17)30007-6 https://pbs.twimg.com/media/C409vuFWMAAHoHs.jpg (@CurrentBiology) 17:32 < kanzure> eudoxia: you're alive! 17:33 < eudoxia> :D 17:36 < kanzure> "Microfluidic droplet platform for ultrahigh-throughput single-cell screening of biodiversity" http://www.pnas.org/content/early/2017/02/14/1621226114.long 17:37 < kanzure> "Mapping the protein fold universe using the camtube force field in molecular dynamics simulations" http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1004435 17:39 < kanzure> "A one-piece 3D printed flexure translation stage for open-source microscopy" http://aip.scitation.org/doi/full/10.1063/1.4941068 17:39 < kanzure> see also http://hackaday.com/2017/02/17/this-3d-printed-microscope-bends-for-50nm-precision/ 17:40 < kanzure> https://github.com/rwb27/openflexure_microscope 18:23 -!- Gurkenglas [~Gurkengla@dslb-178-005-218-116.178.005.pools.vodafone-ip.de] has quit [Ping timeout: 240 seconds] 18:31 -!- eudoxia [~eudoxia@r186-48-29-50.dialup.adsl.anteldata.net.uy] has quit [Quit: Leaving] 18:33 -!- eudoxia [~eudoxia@r186-48-29-50.dialup.adsl.anteldata.net.uy] has joined ##hplusroadmap 18:45 -!- eudoxia_ [~eudoxia@r186-55-178-9.dialup.adsl.anteldata.net.uy] has joined ##hplusroadmap 18:48 -!- eudoxia [~eudoxia@r186-48-29-50.dialup.adsl.anteldata.net.uy] has quit [Ping timeout: 240 seconds] 19:08 -!- darsie [~darsie@84-113-55-42.cable.dynamic.surfer.at] has joined ##hplusroadmap 19:19 -!- jtimon [~quassel@245.30.134.37.dynamic.jazztel.es] has quit [Ping timeout: 240 seconds] 19:24 < poppingtonic> http://www.nextbigfuture.com/2017/02/george-church-indicates-reversal-of.html 19:24 < poppingtonic> .title 19:24 < yoleaux> Next Big Future: George Church indicates reversal of aging will be a reality within ten years 19:40 < kanzure> "This new method, called fluorescent in situ sequencing, or FISSEQ, allows us to count all the RNAs in a cell while simultaneously counting all of the RNAs in all of the cells it touches. Plus, we get the 3D coordinates for every RNA molecule in every cell." 19:41 < kanzure> "A third way is to use a specialized highly genomic strategy, such as mutating thousands of genes one by one to see if any of these mutations block aging, or using the FISSEQ method we discussed earlier." 19:41 < kanzure> "Our protocol will likely be to collect leads from the four different sources and try them out first on human cells. By going straight to human cells, we won't get into the trap of spending years working on mice, which is rather expensive, only to find out that it doesn't work in humans. We can actually do a cheaper and more relevant study in human cells, confirm them in mice, then test them i... 19:41 < kanzure> ...n larger animals, and then in humans. I think that going from human cells to mice and back to humans is likely to save us time and money. Many human cellular testing systems are getting better and better, such as "organs on a chip" or organoids, which are getting to be more and more representative of in vivo biology." 19:42 -!- drewbot [~cinch@ec2-54-221-120-142.compute-1.amazonaws.com] has quit [Remote host closed the connection] 19:42 -!- drewbot [~cinch@ec2-54-146-160-224.compute-1.amazonaws.com] has joined ##hplusroadmap 19:43 < kanzure> .wik TFAM 19:43 < yoleaux> "Mitochondrial transcription factor A, abbreviated as TFAM or mtTFA, is a protein that in humans is encoded by the TFAM gene." -- https://en.wikipedia.org/wiki/TFAM 20:06 < poppingtonic> https://www.healthnucleus.com/ 20:06 < poppingtonic> .title 20:06 < yoleaux> Health Nucleus 20:46 -!- eudoxia_ [~eudoxia@r186-55-178-9.dialup.adsl.anteldata.net.uy] has quit [Quit: Leaving] 22:58 -!- CRM114 [~urchin@unaffiliated/urchin] has quit [Ping timeout: 240 seconds] 22:59 -!- Urchin [~urchin@unaffiliated/urchin] has quit [Ping timeout: 240 seconds] 23:13 -!- yashgaroth [~yashgarot@2602:306:35fa:d500:f5e0:f867:a11d:8d52] has quit [Quit: Leaving] --- Log closed Sat Feb 18 00:00:36 2017