--- Log opened Thu Mar 09 00:00:53 2017
00:48 < archels> .title https://www.ncbi.nlm.nih.gov/pubmed/16529878
00:48 < yoleaux> The effect on health of alternate day calorie restriction: eating less and more than needed on alternate days prolongs life. - PubMed - NCBI
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04:44 < kanzure> bloop
04:47 < kanzure> drag-and-drop protein design tool thingy https://serotiny.bio/
04:48 < kanzure> 'notes on useful proteins' https://serotiny.bio/notes/proteins/
04:49 < kanzure> cas9 json dump https://serotiny.bio/api/parts/10179
04:49 < kanzure> "Protein structure determination using metagenome sequence data" http://science.sciencemag.org/content/355/6322/294
04:51 < kanzure> from https://news.ycombinator.com/item?id=13825805
05:02 < bluebear_> very interesting!
05:05 < kanzure> is that all you say around here
05:22 < bluebear_> well...
05:22 < bluebear_> but it really is very interesting...
05:22 < bluebear_> I definitely refuse being a bot, if you think around these lines :-D
05:23 < bluebear_> serotiny.bio is, in fact, not only interesting, but also cute
05:24 < bluebear_> generally, I'm floating here to see new information about science, to alleviate my depression and feeling that nothing changes, only circling in a spiral into Hell
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06:02 < kanzure> well i didn't mean for you to leave
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06:21 < JayDugger> Pfui.
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06:46 < kanzure> from "Children of Cthulhu" http://web.archive.org/web/20110720183444/http://www.thesmartpolitenerd.com/principlesandparameters.html
06:56 < kanzure> "Cas9-mediated genome editing in the methanogenic archaeon Methanosarcina acetivorans" http://www.pnas.org/content/early/2017/03/01/1618596114
07:01 < JayDugger> Ayup. Better collections since. <INSERT CURMUDGEONLY PROOF OF MORE TIME WASTED READING SF, F, & H>
07:03 < kanzure> that one was of note because the author is someone we know
07:03 < JayDugger> Oh?
07:03 < kanzure> maradydd, although she hasn't been around here in a long time
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07:04 < JayDugger> I think before my time.
07:05 < JayDugger> And careful with the plural first person, you'll start to lend credence to that Twitter rumor that "kanzure" exists as a shell identity for multiple people.
07:06 < cluckj> there's a rumor about that?
07:07 < cluckj> that's kinda neat
07:07 < kanzure> there are many rumors about me http://heybryan.org/mac.html
07:07 < JayDugger> Explains those high-speed conference talk transcripts, doesn't it.
07:07 < cluckj> lol
07:07 < cluckj> he just types very fast, I've seen it
07:08 < kanzure> ancient technique taught by shoalin monks
07:08 < kanzure> shaolin monks, rather.
07:12 < JayDugger> Your claim confirms your participation in at least a disinformation campaign, if not in the conspiracy(TM)itself, cluckj.
07:13 < cluckj> I'm actually a bot
07:13 < TMA> ah, the carefully inserted typo to hint the fallible human nature
07:14 < JayDugger> If I had had more coffee, then I'd consider my point proved. As of now, I lack enthusiasm for such. And TMA's right. They(TM)wouldn't make that mistake unless they wanted to send a message to those in the know.
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11:17 < entity8421[m]> is there something like Getting Things Done but with wider view, for transhumanist/singularity-whores?
11:18 < entity8421[m]> *time/self-management system
11:21 < kanzure> socialize with people who are more productive than you by a few orders of magnitude, problem solved
11:21 < kanzure> it's contagious.
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11:58 < kanzure> https://github.com/petertodd/python-bitcoinlib/pull/136
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13:27 < chris_99> .title http://www.bbc.com/news/uk-scotland-34583642
13:27 < yoleaux> The woman who can smell Parkinson's disease - BBC News
13:30 < chris_99> Out of interest, has anyone seen something kind of like a robot arm, but just manually positionable, with a clamp at the end
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16:22 < kanzure> .tell JayDugger what is the best airline checklist you've ever seen? ideally one that you can link me to.
16:22 < yoleaux> kanzure: I'll pass your message to JayDugger.
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17:16 < pasky_> entity8421[m]: kanzure's advice actually works great; but more permissively, (A) just socialize with people to do stuff, it'll put peer pressure on yourself, (B) avoid people with lazy culture, (C) pick people who work on similar stuff and you can talk to them about what you do; "socialize" doesn't mean "IRC" but real world where it's apparent to everyone if you are gaming or coding at any moment; RE
17:16 < pasky_> SOLVED FIXED
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20:16  * kanzure scratches his head, https://tools.ietf.org/html/rfc6781
20:21 < kanzure> and https://tools.ietf.org/html/rfc3833
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20:34 < kanzure> "A visual motion detection circuit suggested by Drosophila connectomics" http://www.nature.com/nature/journal/v500/n7461/full/nature12450.html
20:34 < kanzure> "Functional Specialization of Neural Input Elements to the Drosophila ON Motion Detector" https://www.ncbi.nlm.nih.gov/pubmed/26234212
20:37 < kanzure> "Wiring specificity in the direction-selectivity circuit of the retina" http://www.nature.com/nature/journal/v471/n7337/full/nature09818.html
20:38 < kanzure> connectomics/microprocessor paper shows up again https://news.ycombinator.com/item?id=13821481
20:40 < kanzure> "A Computational Model of Systems Memory Reconsolidation and Extinction" https://arxiv.org/abs/1703.01357
20:40 < kanzure> "CRISPR/Cas9 screening using unique molecular identifiers" http://biorxiv.org/content/early/2017/03/06/114355
20:43 < kanzure> "Coordinated movement of vesicles and actin bundles during nerve growth revealed by superresolution microscopy" http://www.cell.com/cell-reports/fulltext/S2211-1247(17)30173-0?sf59930047=1 https://twitter.com/CellReports/status/838839366546034688
20:44 < kanzure> "Epilepsy and intellectual disability linked protein Shrm4 interaction with GABABRs shapes inhibitory neurotransmission" http://www.nature.com/articles/ncomms14536
20:45 < kanzure> "... we report that Shrm4 is localized to synapses where it regulates dendritic spine morphology and interacts with the C terminus of GABAB receptors (GABABRs) to control their cell surface expression and intracellular trafficking via a dynein-dependent mechanism."
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--- Log closed Fri Mar 10 00:00:54 2017