--- Log opened Thu Apr 06 00:00:19 2017 00:11 -!- ebowden [~ebowden@1.136.96.216] has joined ##hplusroadmap 00:11 -!- ebowden [~ebowden@1.136.96.216] has quit [Changing host] 00:11 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 00:48 -!- augur [~augur@78.133.1.73] has joined ##hplusroadmap 00:52 -!- augur [~augur@78.133.1.73] has quit [Ping timeout: 268 seconds] 01:12 -!- Wikiscratch [~wikiscrat@209.58.129.99] has quit [Quit: Textual IRC Client: www.textualapp.com] 01:31 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Remote host closed the connection] 01:32 -!- ebowden [~ebowden@1.136.96.216] has joined ##hplusroadmap 01:32 -!- ebowden [~ebowden@1.136.96.216] has quit [Changing host] 01:32 -!- ebowden [~ebowden@unaffiliated/ebowden] has joined ##hplusroadmap 01:36 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [Ping timeout: 260 seconds] 01:39 -!- ebowden [~ebowden@1.136.97.6] has joined ##hplusroadmap 01:39 -!- ebowden [~ebowden@1.136.97.6] has quit 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03:47 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 264 seconds] 03:47 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap 04:01 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 04:23 -!- augur [~augur@78.133.119.198] has quit [Remote host closed the connection] 04:27 -!- dnukem|2 [~dnukem@c-71-234-96-215.hsd1.ma.comcast.net] has quit [Ping timeout: 268 seconds] 04:28 < kanzure> blort 2 04:44 < kanzure> .title https://cibolo.us/pipermail/open_electroporator/2017-April/000458.html 04:44 < yoleaux> [Open_electroporator] HV board reading 'shorted' between 20V and GND 04:57 -!- JayDugger [~jwdugger@47.185.237.246] has joined ##hplusroadmap 05:02 -!- JayDugger [~jwdugger@47.185.237.246] has quit [Quit: Leaving.] 05:07 -!- justan0theruser [~justanoth@unaffiliated/justanotheruser] has quit [Quit: WeeChat 1.5] 05:07 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 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[~chris_99@unaffiliated/chris-99/x-3062929] has quit [Remote host closed the connection] 09:03 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap 09:08 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Quit: Leaving] 09:15 -!- TinKode [~TinKode@unaffiliated/tinkode] has joined ##hplusroadmap 09:26 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap 09:32 -!- bsm117532 [~mcelrath@135.84.167.210] has quit [Ping timeout: 268 seconds] 09:37 -!- sachy [~sachy@nat.brmlab.cz] has joined ##hplusroadmap 10:41 -!- TinKode [~TinKode@unaffiliated/tinkode] has quit [Quit: Practicing escapism.] 11:06 < kanzure> bloort 11:09 -!- jtimon [~quassel@70.30.134.37.dynamic.jazztel.es] has quit [Ping timeout: 256 seconds] 11:43 -!- Gurkenglas [~Gurkengla@dslb-178-000-209-129.178.000.pools.vodafone-ip.de] has quit [Ping timeout: 256 seconds] 11:50 -!- pent [~pent@138.197.129.246] has quit [Read error: Connection reset by peer] 11:50 -!- pent [~pent@138.197.129.246] has joined ##hplusroadmap 11:56 -!- jtimon [~quassel@70.30.134.37.dynamic.jazztel.es] has joined ##hplusroadmap 12:06 < archels> any optics gurus know what "0.546-32" screw thread means? 12:07 < kanzure> fenn knows various screw thread things 12:11 -!- bsm117532 [~mcelrath@135.84.167.210] has joined ##hplusroadmap 12:29 -!- nmz787_i [~ntmccork@134.134.139.76] has joined ##hplusroadmap 12:31 < nmz787_i> brrrrrr---upppp--chhhhhh-krrrrrrr-beeeeeeeeeeeeep 12:37 < nmz787_i> sweet, I emailed the prof who was on that ProtSAT paper, and she CCed some other person, who replied they don't have SourceForge permissions but emailed me the (some?) files 12:54 < kanzure> nmz787_i: these guys don't believe that you can have an electron microscope :o https://www.reddit.com/r/Bitcoin/comments/63rtuv/this_guy_reverse_engineered_a_mining_chip_to/dfx7xay/?context=3 12:56 -!- sachy [~sachy@nat.brmlab.cz] has quit [Quit: Leaving.] 12:56 < chris_99> heh 13:02 < nmz787_i> yeah it is actually a dishwasher 13:04 < kanzure> so you admit it 13:04 < nmz787_i> :( 13:05 < nmz787_i> I wash my dishes with an e-beam 13:05 < nmz787_i> my way of contributing to global warming 13:06 < archels> 06/21:01:51 < dnova_> like openscad so far? 13:06 < archels> 06/21:04:38 < archels> yeah, it's great 13:06 < archels> 06/21:05:11 < archels> I'm cautiously optimistic about it being fantastic 13:08 -!- nmz787_i1 [~ntmccork@134.134.139.76] has joined ##hplusroadmap 13:08 -!- nmz787_i [~ntmccork@134.134.139.76] has quit [Remote host closed the connection] 13:11 < nmz787_i1> archels: when you get sick of openscad: https://github.com/nmz787/python-brlcad-tcl 13:12 < nmz787_i1> kanzure: you got a reply on that reddit post.... I guess linking to azonenberg's work wouldn't qualify, since he did a lot of it in a school lab 13:12 < nmz787_i1> (I think it was in a school lab) 13:13 < chris_99> i missed what they're talking about, but the RE'd a chip?, what nm process was it? 13:15 < chris_99> also what is ASICboost? 13:16 -!- nmz787_i [~ntmccork@134.134.139.74] has joined ##hplusroadmap 13:16 < nmz787_i> kanzure: I backed you up ;) 13:17 -!- nmz787_i1 [~ntmccork@134.134.139.76] has quit [Remote host closed the connection] 13:17 < kanzure> chris_99: asicboost is described in https://lists.linuxfoundation.org/pipermail/bitcoin-dev/2017-April/013996.html 13:18 < chris_99> cheers 13:20 < nmz787_i> I don't understand the whole 'covert' thing... why would a hardware company disclose their tech, if it was poised to make them oodles of $$$ ? 13:20 < chris_99> nmz787_i, heh your friend has a FIB? nice 13:20 < kanzure> nmz787_i: the 'covert' implementation is not detectable on the network. the 'overt' implementation is really obvious and can be discovered by looking at some bytes. 13:20 < nmz787_i> well, friend with a commercial business in FIBing stuff.... but who lets me play as I want, pretty much 13:21 < chris_99> cool 13:21 < nmz787_i> kanzure: but I guess, why does it matter if people tell how they play the game, as long as the rules/protocol isn't broken? 13:22 < nmz787_i> by being overt, do they gain in performance? 13:22 < nmz787_i> by being covert, were they trying to use unlicensed patents? 13:22 < nmz787_i> I mean, not pay for a license 13:24 < kanzure> the point of the game is to be fair--- but the proposal on the table is not to *disable* asicboost, it's to disable the covert version. 13:24 < kanzure> the problem is that a 30% performance optimization is way beyond the margins that other miners are operating at (like <10%) 13:25 < kanzure> so it has a huge centralizing effect 13:25 < kanzure> also the other problem is that it is incompatible with segwit and other protocol upgrades 13:28 < nmz787_i> yeah 13:29 < nmz787_i> I didn't understand, til now, that the proposal was to force them to be overt (or rather, disable the covert version) 13:31 < kanzure> correct. 13:32 < kanzure> also the overt version doesn't interfere with protocol upgrades. 13:42 -!- sachy [~sachy@nat.brmlab.cz] has joined ##hplusroadmap 13:44 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 13:47 < nmz787_i> too bad someone wouldn't offer me a ton of money to decap and SEM bitcoin chips 13:47 < nmz787_i> wouldn't/hasn't 13:49 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 260 seconds] 13:57 < kanzure> nmz787_i: are you offering? 14:21 < nmz787_i> kanzure: well, I already have a billion parallel projects, but the SEM is already one of those... so a request for me to use it would be motivational 14:23 < kanzure> these chips are like $2300/ea 14:23 < nmz787_i> hmm 14:24 < nmz787_i> I was going to say that I could probably get FIB time if it was needed sooner than 'sometime in the future' 14:24 < nmz787_i> probably meaning, most likely, as long as it was in the evening 14:35 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Quit: Leaving] 15:15 -!- bsm117532 [~mcelrath@135.84.167.210] has quit [Ping timeout: 264 seconds] 15:20 -!- CHCl3 [~CHCl3@109.227.144.239] has joined ##hplusroadmap 15:20 -!- abetusk [~abe@68.175.143.22] has quit [Ping timeout: 240 seconds] 15:25 < nmz787_i> I read SegWit but want to hear Sedgewick 15:30 -!- nmz787_i [~ntmccork@134.134.139.74] has quit [Ping timeout: 260 seconds] 15:31 < kanzure> nmz787_i: http://diyhpl.us/wiki/transcripts/scalingbitcoin/hong-kong/segregated-witness-and-its-impact-on-scalability/ 15:31 < kanzure> and http://diyhpl.us/wiki/transcripts/scalingbitcoin/milan/segwit-lessons-learned/ 15:33 -!- abetusk [~abe@68.175.143.22] has joined ##hplusroadmap 15:34 -!- abetusk is now known as Guest54002 15:39 -!- nmz787_i [~ntmccork@134.134.139.83] has joined ##hplusroadmap 15:56 -!- Guest54002 is now known as abetusk 16:06 < nmz787_i> kanzure: cool, will check them out... the article written by the journalist you posted a day or so ago was pretty good, but yeah I don't think it went into SegWit details at all 16:10 -!- CHCl3 [~CHCl3@109.227.144.239] has quit [Read error: Connection reset by peer] 16:11 -!- CHCl3 [~CHCl3@109.227.144.239] has joined ##hplusroadmap 16:15 -!- cevi_ [~zeb@128.12.245.10] has quit [Ping timeout: 264 seconds] 16:16 -!- cevi_ [~zeb@128.12.245.10] has joined ##hplusroadmap 17:14 -!- helleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has joined ##hplusroadmap 17:40 -!- CHCl3 [~CHCl3@109.227.144.239] has quit [Read error: Connection reset by peer] 17:41 -!- CHCl3 [~CHCl3@109.227.144.239] has joined ##hplusroadmap 17:59 < nmz787_i> anyone know of a JTAG/TAP state machine emulator/decoder/simulator? 18:04 -!- darsie [~darsie@84-113-55-42.cable.dynamic.surfer.at] has quit [Ping timeout: 260 seconds] 18:09 < nmz787_i> (in Python) 18:22 -!- abetusk [~abe@68.175.143.22] has quit [Ping timeout: 260 seconds] 18:32 < ebowden> kanzure, where would you get the money to hire a chemist? 18:34 < kanzure> i make a tremendous amount of money. 18:36 < ebowden> Wow. 18:36 < ebowden> How? 18:37 < ebowden> I thought to be in this channel you have to shave your head, wear potato sacks and live in a flophouse. 18:38 < ebowden> kanzure, are you telling me you don't live in a flophouse? 18:38 < kanzure> ebowden: for a while i was represented by these guys http://www.newyorker.com/magazine/2014/11/24/programmers-price 18:39 -!- abetusk [~abe@68.175.143.22] has joined ##hplusroadmap 18:40 < ebowden> You're a "coding superstar"? 18:40 -!- abetusk is now known as Guest92949 18:40 < kanzure> you disagree? 18:44 < ebowden> No, I don't really have a way of evaluating it. 18:44 < ebowden> So, you get lots of money by being able to do the work of a lot of people? 18:45 < kanzure> i write beautiful, high-performance, well-documented software. quickly. 18:46 < ebowden> All this time I thought you were a biosciences guy with a passing interest in bitcoin and linux. 18:46 < kanzure> there's a high demand for programming talent, definitely. but also there's a premium for my number of other talents and areas of knowledge. 18:46 < kanzure> nah i am shit at biology 18:46 < nmz787_i> I feel like I'd easily be 5x more productive if I could type as fast as kanzure 18:46 < ebowden> "The first person who comes to mind, he's also a bioinformatician." 18:46 < ebowden> kanzure, is he talking about you? 18:47 < kanzure> i have done bioinformatics projects, but he probably wasn't thinking about me---- twitter api is trivial. 18:48 < kanzure> oh also i haven't worked at scripss, so... 18:48 < nmz787_i> ebowden: no, read on... Max Nanis 18:49 < nmz787_i> "he sleeps three hours a day" 18:49 < nmz787_i> also apparently 24 years old... so this dude def seems like has some genetic advantages, if not also good parenting and knowledge loading from early on 18:50 < nmz787_i> or drugs, lots of drugs 18:50 < nmz787_i> that also would boost my productivity 18:50 < nmz787_i> but I am not really pro long-acting stimulants 18:51 < ebowden> PRL-8-53 is hypermnesic, most potent effects seen the longer you go out from when the subjects were shown the random sequence. 18:54 < ebowden> kanzure, you should probably get in touch with more people if you want to hire a good chemist. 18:55 < kanzure> it's been tricky figuring out where to find an appropriate chemist. most of them want to work for actual companies that can promise stable salary. 18:55 < kanzure> and, you know, they don't really like the idea of working for a shady irc channel project 18:57 < ebowden> Can you promise a stable salary? 18:58 < ebowden> An employment contract, a bunch of money held in an account? 18:58 < kanzure> nah it would probably be a consulting project structure 18:58 < kanzure> where i would pay them upfront and upon milestone completion (or hourly) 18:58 < ebowden> So, you'll have to look for consultants specifically? 18:58 < kanzure> it's more of a brand thing for some chemists. in academia, for instance, it is important that you work for established academic institutions. 19:04 < ebowden> Find a brilliant chemist who's just got out of prison for putting his talents to work doing huge, brilliantly executed methamphetamine synths. 19:04 < ebowden> He might be happy for the work. 19:10 -!- CHCl3 [~CHCl3@109.227.144.239] has quit [Read error: Connection reset by peer] 19:11 -!- CHCl3 [~CHCl3@109.227.144.239] has joined ##hplusroadmap 19:25 < nmz787_i> I've heard of a guy like that, name is Walter White 19:26 < nmz787_i> I bet people would love to make a documentary on this too 19:27 < nmz787_i> VLOG it 19:34 -!- jtimon [~quassel@70.30.134.37.dynamic.jazztel.es] has quit [Ping timeout: 240 seconds] 19:49 -!- justan0theruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 19:51 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has quit [Ping timeout: 264 seconds] 19:52 -!- yashgaroth [~yashgarot@2606:6000:cd4d:3300:f5e0:f867:a11d:8d52] has joined ##hplusroadmap 20:10 < kanzure> "Covalent protein labeling by SpyTag-SpyCatcher in fixed cells for super-resolution microscopy" http://biorxiv.org/content/early/2017/04/06/125013 https://twitter.com/biorxivpreprint/status/850060561773719554 20:13 < kanzure> "Engrams and circuits crucial for systems consolidation of a memory" http://science.sciencemag.org/content/356/6333/73 20:14 < kanzure> "Femtosecond x-ray spectroscopy of an electrocyclic ring-opening reaction" http://science.sciencemag.org/content/356/6333/54 20:14 < kanzure> "Normal sleep requires the astrocyte brain-type fatty acid binding protein FABP7" http://advances.sciencemag.org/content/3/4/e1602663 20:15 < kanzure> "We found that the missense mutation FABP7.T61M is associated with fragmented sleep in humans. This phenotype was recapitulated in mice and fruitflies bearing similar mutations: Fabp7-deficient mice and transgenic flies that express the FABP7.T61M missense mutation in astrocytes also show fragmented sleep. These results provide novel evidence for a distinct molecular pathway linking lipid-sign... 20:15 < kanzure> ...aling cascades within astrocytes in sleep regulation among phylogenetically disparate species." 20:17 < kanzure> https://www.scientificamerican.com/article/seeking-pig-organs-for-human-transplants/ https://twitter.com/sciam/status/850001421550407680 20:18 < kanzure> "Yang, eGenesis's chief scientific officer, has already made enormous strides, scientific and financial. In 2015, she and colleagues in Church's lab used CRISPR to eliminate from pig cells 62 genes so potentially dangerous their very existence nixed previous efforts to turn pigs into organ donors. Last month, eGenesis announced that it had raised $38 million from investors. The next hurdle... 20:18 < kanzure> ...: get the surrogate-mother sows that are pregnant with genetically altered embryos to give birth to healthy piglets." 20:18 -!- CHCl3 [~CHCl3@109.227.144.239] has quit [Remote host closed the connection] 20:20 < jcorgan> worst case you can still make some really tasty lechon 20:21 < kanzure> "In a 2015 story, Technology Review portrayed her as exploring how to use CRISPR for "engineering the perfect baby" whose bespoke DNA would be inherited by future generations. Yang and Church say she wasn't doing that, and that her difficulty with English led to a misunderstanding. The story "was probably her first [interview]," Church said. It "painted a picture of her working on ... 20:21 < kanzure> ...a human germline project, when she had just been learning about human oocytes" for the pig genome engineering." 20:21 < kanzure> "Technology Review said it stands by its story: "Luhan Yang very clearly revealed to us a plan to edit cells of the human germline. No babies involved," the magazine said in a statement." 21:18 -!- dnukem [~dnukem@c-71-234-96-215.hsd1.ma.comcast.net] has joined ##hplusroadmap 21:37 -!- cevi_ [~zeb@128.12.245.10] has quit [Ping timeout: 264 seconds] 21:38 -!- cevi_ [~zeb@128.12.245.10] has joined ##hplusroadmap 21:42 -!- dnukem [~dnukem@c-71-234-96-215.hsd1.ma.comcast.net] has left ##hplusroadmap ["No boundaries on the net!"] 21:42 -!- justan0theruser is now known as justanotheruser 22:32 -!- yashgaroth [~yashgarot@2606:6000:cd4d:3300:f5e0:f867:a11d:8d52] has quit [Quit: Leaving] 22:39 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has quit [Quit: sleep] 22:47 -!- aedla [~quassel@c21-76.uvn.zone.eu] has quit [Quit: ["hip","hip"] array!] 22:59 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 23:02 -!- hehelleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has joined ##hplusroadmap 23:04 -!- TC [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has joined ##hplusroadmap 23:04 -!- helleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has quit [Ping timeout: 246 seconds] 23:04 -!- TC is now known as Guest85285 23:06 -!- hehelleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has quit [Ping timeout: 246 seconds] 23:39 -!- cevi_ [~zeb@128.12.245.10] has quit [Ping timeout: 264 seconds] 23:40 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 240 seconds] 23:54 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap --- Log closed Fri Apr 07 00:00:19 2017