--- Log opened Mon Apr 10 00:00:22 2017 00:03 -!- fleshtheworld [~fleshthew@2602:306:cf0f:4c20:898d:6243:25f9:8654] has joined ##hplusroadmap 00:19 -!- Gurkenglas_ [~Gurkengla@dslb-178-000-215-240.178.000.pools.vodafone-ip.de] has joined ##hplusroadmap 01:12 -!- augur [~augur@94.119.64.9] has joined ##hplusroadmap 01:13 -!- augur [~augur@94.119.64.9] has quit [Remote host closed the connection] 01:14 -!- augur [~augur@94.119.64.25] has joined ##hplusroadmap 01:23 -!- jtimon [~quassel@70.30.134.37.dynamic.jazztel.es] has joined ##hplusroadmap 02:36 -!- augur [~augur@94.119.64.25] has quit [Remote host closed the connection] 02:47 -!- Douhet [~Douhet@unaffiliated/douhet] has quit [Read error: Connection reset by peer] 03:03 -!- fleshtheworld [~fleshthew@2602:306:cf0f:4c20:898d:6243:25f9:8654] has quit [Quit: Leaving] 03:09 -!- ebowden [~ebowden@unaffiliated/ebowden] has quit [] 03:23 -!- Douhet [~Douhet@unaffiliated/douhet] has joined ##hplusroadmap 03:35 -!- charlie [~spoar@104.238.169.42] has quit [Ping timeout: 240 seconds] 03:36 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap 03:49 -!- charlie [~spoar@104.238.169.128] has joined ##hplusroadmap 03:58 < kanzure> i wonder if that works with sympy. 04:24 < archels> .gc "post-posthuman" 04:24 < yoleaux> 519 (site), 368 (end) 04:53 -!- chris_999 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap 04:57 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Ping timeout: 245 seconds] 04:58 -!- Gurkenglas [~Gurkengla@dslb-188-106-113-043.188.106.pools.vodafone-ip.de] has joined ##hplusroadmap 04:58 -!- chris_999 is now known as chris_99 05:00 -!- Gurkenglas_ [~Gurkengla@dslb-178-000-215-240.178.000.pools.vodafone-ip.de] has quit [Ping timeout: 252 seconds] 05:27 -!- darsie [~darsie@84-113-55-42.cable.dynamic.surfer.at] has joined ##hplusroadmap 07:14 -!- jtimon [~quassel@70.30.134.37.dynamic.jazztel.es] has quit [Ping timeout: 240 seconds] 07:33 < kanzure> "Right, so. I listed many that some people list on their wish list, their so called post-human or transhumanist wishlist. But most of those can be handled by chemistry and physics quite adequately. I "wouldn't" say I want to change my genome so that I can fly into space without a spacesuit." 07:47 -!- charlie [~spoar@104.238.169.128] has quit [Ping timeout: 260 seconds] 08:08 -!- Gurkenglas_ [~Gurkengla@dslb-178-000-183-200.178.000.pools.vodafone-ip.de] has joined ##hplusroadmap 08:08 -!- opiate [~spoar@104.238.169.103] has joined ##hplusroadmap 08:10 -!- Gurkenglas [~Gurkengla@dslb-188-106-113-043.188.106.pools.vodafone-ip.de] has quit [Ping timeout: 255 seconds] 08:17 -!- cluckj [~cluckj@static-98-114-125-87.phlapa.ftas.verizon.net] has quit [Quit: Leaving] 08:18 < opiate> Hello all 08:21 < kanzure> greets 08:21 < archels> kanzure: some things might be better left externalised 08:22 < archels> living in the vacuum of space has its downsides, I'm not sure I want to adapt my body for all of that 08:22 < archels> something that would probably be quite the kludge 08:22 < kanzure> there was this old post somewhere that had calculations about total required surface area for a human in the vacuum of space to be powered only by photosynthesis, it was a lot of surface area. 08:24 < archels> how does it compare to photosynthesis-only on the surface of Earth, though? 08:34 < kanzure> dunno. 08:34 < kanzure> both are ridiculous :) 08:37 < kanzure> hmm i just found an old business plan of mine for 'total planetary domination', i calculated the total value of the planet based on enslaving the human race and assuming an average wage of $2.39/hour USD and a few hundred billion hours of labor per year. 08:38 -!- jtimon [~quassel@70.30.134.37.dynamic.jazztel.es] has joined ##hplusroadmap 08:38 < kanzure> wait, had to be more than a few hundred billion hours of labor, that's not enough. 08:41 < kanzure> the interesting thing is that world domination might only cost a few billion dollars (or less), and has a pretty high value outcome. 09:23 -!- augur [~augur@94.119.64.21] has joined ##hplusroadmap 09:33 < kanzure> "Finally, we invite you to submit Abstracts for additional GP-write pilot projects by the end of April." 09:33 < kanzure> send to info@engineeringbiologycenter.org and lisa@novangroup.com 09:36 < opiate> wtf kanzure 09:43 -!- Jen [~Jen@cpc76808-brmb10-2-0-cust571.1-3.cable.virginm.net] has quit [Read error: Connection reset by peer] 09:43 -!- Jen3 [~Jen@cpc76808-brmb10-2-0-cust571.1-3.cable.virginm.net] has joined ##hplusroadmap 09:46 < kanzure> hm? 09:51 < kanzure> "Genes and signaling pathways involved in memory enhancement in mutant mice" https://molecularbrain.biomedcentral.com/articles/10.1186/1756-6606-7-43 (2014) 10:00 -!- Jen [~Jen@cpc76808-brmb10-2-0-cust571.1-3.cable.virginm.net] has joined ##hplusroadmap 10:00 -!- Jen3 [~Jen@cpc76808-brmb10-2-0-cust571.1-3.cable.virginm.net] has quit [Read error: Connection reset by peer] 10:00 -!- opiate [~spoar@104.238.169.103] has quit [Ping timeout: 252 seconds] 10:04 -!- Jen [~Jen@cpc76808-brmb10-2-0-cust571.1-3.cable.virginm.net] has quit [Read error: Connection reset by peer] 10:04 -!- Jen3 [~Jen@cpc76808-brmb10-2-0-cust571.1-3.cable.virginm.net] has joined ##hplusroadmap 10:09 -!- Jen [~Jen@cpc76808-brmb10-2-0-cust571.1-3.cable.virginm.net] has joined ##hplusroadmap 10:09 -!- Jen3 [~Jen@cpc76808-brmb10-2-0-cust571.1-3.cable.virginm.net] has quit [Read error: No route to host] 10:13 -!- nmz787_i [~ntmccork@134.134.139.82] has joined ##hplusroadmap 10:13 < nmz787_i> sup all you differentiate germ layers? 10:13 < nmz787_i> differentiated* 10:19 -!- Jen3 [~Jen@cpc76808-brmb10-2-0-cust571.1-3.cable.virginm.net] has joined ##hplusroadmap 10:19 -!- Jen [~Jen@cpc76808-brmb10-2-0-cust571.1-3.cable.virginm.net] has quit [Read error: Connection reset by peer] 10:21 -!- Jen [~Jen@cpc76808-brmb10-2-0-cust571.1-3.cable.virginm.net] has joined ##hplusroadmap 10:24 -!- Jen3 [~Jen@cpc76808-brmb10-2-0-cust571.1-3.cable.virginm.net] has quit [Ping timeout: 245 seconds] 10:25 -!- Jen3 [~Jen@cpc76808-brmb10-2-0-cust571.1-3.cable.virginm.net] has joined ##hplusroadmap 10:26 -!- Jen [~Jen@cpc76808-brmb10-2-0-cust571.1-3.cable.virginm.net] has quit [Ping timeout: 252 seconds] 10:27 -!- Jen [~Jen@cpc76808-brmb10-2-0-cust571.1-3.cable.virginm.net] has joined ##hplusroadmap 10:27 < kanzure> nmz787_i: i was looking at this old email thread https://groups.google.com/forum/#!topic/diytranshumanist/3kBK6WCUBgc 10:31 < kanzure> .tw https://twitter.com/brainmaps/status/850288882843344896 10:31 < yoleaux> Preparing to unveil whole mouse brain serial-section EM for cellular connectomics at Berlin conference this weekend. Very exciting! (@brainmaps) 10:31 -!- Jen3 [~Jen@cpc76808-brmb10-2-0-cust571.1-3.cable.virginm.net] has quit [Ping timeout: 255 seconds] 10:31 < kanzure> .tw https://twitter.com/McGuy/status/849686326123216896 10:31 < yoleaux> My objective w/@KernelCo is to be able to read and write the underlying functions of the human brain @bryan_johnson https://goo.gl/7TCZO7 (@McGuy) 10:32 -!- Jen3 [~Jen@cpc76808-brmb10-2-0-cust571.1-3.cable.virginm.net] has joined ##hplusroadmap 10:32 < kanzure> more kernel.co things https://www.theregister.co.uk/2017/04/05/building_bridges_to_the_brain/ 10:33 < kanzure> .tw https://twitter.com/neuroecology/status/847908279015657475 10:33 < yoleaux> Whole brain imaging in freely moving hydras... From @yusterafa http://gph.is/2nEPIH9 via @GIPHY https://video.twimg.com/tweet_video/C8RgERkUAAAIbdk.mp4 (@neuroecology) 10:33 < kanzure> "Automatic tracing of ultra-volumes of neuronal images" http://www.nature.com/nmeth/journal/v14/n4/full/nmeth.4233.html 10:34 < kanzure> .tw https://twitter.com/yusterafa/status/847796293506347008 10:34 < yoleaux> We complete the "Brain Activity Map" of an animal: the entire activity of the nervous system of Hydra published http://www.cell.com/current-biology/fulltext/S0960-9822(17)30220-8 (@yusterafa) 10:34 < kanzure> .tw https://twitter.com/bryan_johnson/status/847529301654159360 10:35 < yoleaux> Thoughtful writeup by @TheEconomist on what @elonmusk / Neuralink, @kernel and others are doing in Neurotech http://www.economist.com/news/science-and-technology/21719774-do-human-beings-need-embrace-brain-implants-stay-relevant-elon-musk-enters (@bryan_johnson) 10:35 < nmz787_i> kanzure: I wonder if that visual memory protein is basically disabling 'clearing the video frame buffer'... like mousetrails on Windows 95... i.e. could it be a major disability/distraction 10:35 < kanzure> .tw https://twitter.com/cadnano/status/846916348412256256 10:35 < yoleaux> We are hiring a cadnano developer this year. Contact @smd4 if interested http://bionano.ucsf.edu/contact https://pbs.twimg.com/media/C8DZ2pdVQAMwJV0.png (@cadnano) 10:36 < kanzure> nmz787_i: the paper i mentioned earlier today (from 2014) is a review of rgs14-like things that enhance mouse memory. 10:36 -!- Jen [~Jen@cpc76808-brmb10-2-0-cust571.1-3.cable.virginm.net] has quit [Ping timeout: 252 seconds] 10:36 < kanzure> .tw https://twitter.com/chicaScientific/status/846817241270292480 10:36 < yoleaux> From a $88,554 @NSF grant in 1966, we got PCR thanks to Thermus aquaticus - now ~$8B industry #basicresearchmatters (@chicaScientific) 10:37 < kanzure> https://www.oreilly.com/ideas/adapting-ideas-from-neuroscience-for-ai https://twitter.com/jackclarkSF/status/846794552421732357 10:41 -!- Jen [~Jen@cpc76808-brmb10-2-0-cust571.1-3.cable.virginm.net] has joined ##hplusroadmap 10:41 -!- Jen3 [~Jen@cpc76808-brmb10-2-0-cust571.1-3.cable.virginm.net] has quit [Read error: Connection reset by peer] 10:44 -!- Jen3 [~Jen@cpc76808-brmb10-2-0-cust571.1-3.cable.virginm.net] has joined ##hplusroadmap 10:44 -!- Jen [~Jen@cpc76808-brmb10-2-0-cust571.1-3.cable.virginm.net] has quit [Read error: Connection reset by peer] 10:46 -!- Jen [~Jen@cpc76808-brmb10-2-0-cust571.1-3.cable.virginm.net] has joined ##hplusroadmap 10:46 -!- Jen3 [~Jen@cpc76808-brmb10-2-0-cust571.1-3.cable.virginm.net] has quit [Read error: Connection reset by peer] 10:47 < kanzure> "Gene therapy restores auditory and vestibular function in a mouse model of Usher syndrome type 1c" http://www.nature.com/nbt/journal/v35/n3/full/nbt.3801.html 10:48 -!- Gurkenglas [~Gurkengla@dslb-178-012-146-003.178.012.pools.vodafone-ip.de] has joined ##hplusroadmap 10:49 -!- Gurkenglas_ [~Gurkengla@dslb-178-000-183-200.178.000.pools.vodafone-ip.de] has quit [Ping timeout: 255 seconds] 10:54 < nmz787_i> .wik usher syndrome 10:54 < yoleaux> "Usher syndrome, also known as Hallgren syndrome, Usher-Hallgren syndrome, retinitis pigmentosa-dysacusis syndrome, or dystrophia retinae dysacusis syndrome, is an extremely rare genetic disorder caused by a mutation in any one of at least 11 genes resulting in a combination of hearing loss and visual impairment." -- https://en.wikipedia.org/wiki/Usher_syndrome 10:55 -!- Jen3 [~Jen@cpc76808-brmb10-2-0-cust571.1-3.cable.virginm.net] has joined ##hplusroadmap 10:59 -!- Jen [~Jen@cpc76808-brmb10-2-0-cust571.1-3.cable.virginm.net] has quit [Ping timeout: 255 seconds] 11:01 -!- Jen3 [~Jen@cpc76808-brmb10-2-0-cust571.1-3.cable.virginm.net] has quit [Read error: Connection reset by peer] 11:01 -!- Jen [~Jen@cpc76808-brmb10-2-0-cust571.1-3.cable.virginm.net] has joined ##hplusroadmap 11:03 -!- Jen3 [~Jen@cpc76808-brmb10-2-0-cust571.1-3.cable.virginm.net] has joined ##hplusroadmap 11:03 -!- Jen [~Jen@cpc76808-brmb10-2-0-cust571.1-3.cable.virginm.net] has quit [Read error: Connection reset by peer] 11:12 -!- Jen [~Jen@cpc76808-brmb10-2-0-cust571.1-3.cable.virginm.net] has joined ##hplusroadmap 11:12 -!- Jen3 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[~ntmccork@134.134.139.82] has quit [Ping timeout: 240 seconds] 14:22 -!- streety [streety@2a01:7e00::f03c:91ff:feae:ded6] has joined ##hplusroadmap 14:38 -!- Gurkenglas_ [~Gurkengla@dslb-178-005-161-154.178.005.pools.vodafone-ip.de] has joined ##hplusroadmap 14:39 -!- Gurkenglas [~Gurkengla@dslb-178-012-146-003.178.012.pools.vodafone-ip.de] has quit [Ping timeout: 245 seconds] 14:45 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Quit: Leaving] 14:55 -!- nmz787_i [~ntmccork@134.134.139.82] has joined ##hplusroadmap 14:58 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 240 seconds] 14:59 -!- charlie [~spoar@104.238.169.142] has quit [Ping timeout: 240 seconds] 15:12 -!- charlie [~spoar@104.238.169.12] has joined ##hplusroadmap 15:14 -!- augur [~augur@94.119.64.29] has quit [Read error: Connection reset by peer] 15:15 -!- augur [~augur@94.119.64.17] has joined ##hplusroadmap 15:54 -!- augur [~augur@94.119.64.17] has quit [Remote host closed the connection] 16:17 -!- cluckj [~cluckj@static-98-114-125-87.phlapa.ftas.verizon.net] has joined ##hplusroadmap 16:27 -!- Gurkenglas_ is now known as Gurkenglas 16:32 < nmz787_i> I'm glad Usher syndrome didn't have to do with a rap artist by the same name 16:41 -!- jenelizabeth_ [~jenelizab@cpc76808-brmb10-2-0-cust571.1-3.cable.virginm.net] has quit [Ping timeout: 240 seconds] 16:42 -!- Jen3 [~Jen@cpc76808-brmb10-2-0-cust571.1-3.cable.virginm.net] has quit [Ping timeout: 260 seconds] 16:44 -!- JenElizabeth [~Jen@cpc76808-brmb10-2-0-cust571.1-3.cable.virginm.net] has joined ##hplusroadmap 16:44 -!- JenElizabeth [~Jen@cpc76808-brmb10-2-0-cust571.1-3.cable.virginm.net] has quit [Read error: Connection reset by peer] 16:52 -!- charlie [~spoar@104.238.169.12] has quit [Ping timeout: 252 seconds] 16:53 -!- nmz787_i [~ntmccork@134.134.139.82] has quit [Remote host closed the connection] 16:53 -!- nmz787_i [~ntmccork@134.134.139.82] has joined ##hplusroadmap 17:15 -!- Gurkenglas [~Gurkengla@dslb-178-005-161-154.178.005.pools.vodafone-ip.de] has quit [Ping timeout: 245 seconds] 17:17 -!- Jenda` [~bablbam@dekatron.hrach.eu] has quit [Ping timeout: 240 seconds] 17:23 -!- darsie [~darsie@84-113-55-42.cable.dynamic.surfer.at] has quit [Ping timeout: 260 seconds] 17:24 -!- Jenda` [~bablbam@dekatron.hrach.eu] has joined ##hplusroadmap 17:27 < kanzure> bloop 18:41 < juri_> bleep bloop. 18:46 < kanzure> ah. 18:55 < kanzure> http://www.businessinsider.com/goldman-sachs-space-mining-asteroid-platinum-2017-4 19:13 -!- nmz787_i [~ntmccork@134.134.139.82] has quit [Quit: Leaving.] 19:19 -!- abetusk [~abe@68.175.143.22] has quit [Ping timeout: 240 seconds] 19:22 < juri_> they know what's up. 19:36 < streety> The note itself seems difficult to find. The article is heavy on hype and light on facts 19:36 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has quit [Ping timeout: 240 seconds] 19:37 < streety> Comparing the cost of getting an astronaut to the ISS and Virgin Galactic getting a tourist to space doesn't provide any useful information 19:42 < streety> this seems to be the caltech report mentioned http://www.kiss.caltech.edu/study/asteroid/asteroid_final_report.pdf 20:09 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 21:06 < kanzure> gross, MPEGLA is doing the intellectual property section of hgp-write 21:06 < kanzure> holy shit. 21:16 -!- abetusk [~abe@68.175.143.22] has joined ##hplusroadmap 21:16 -!- abetusk is now known as Guest7713 21:17 < kanzure> "The developing human connectome project (dHCP): a minimal processing pipeline for neonatal cortical surface reconstruction" http://biorxiv.org/content/early/2017/04/07/125526 https://twitter.com/biorxiv_neursci/status/851434714430939141 21:19 < kanzure> oh... MRI. 21:25 < kanzure> why does everyone have such an aversion to physical neuroanatomy under an optical microscope 21:26 < kanzure> i'm not even asking for electron microscopy here 21:45 -!- jtimon [~quassel@70.30.134.37.dynamic.jazztel.es] has quit [Ping timeout: 240 seconds] 22:18 -!- sachy [~sachy@nat.brmlab.cz] has left ##hplusroadmap [] 22:22 -!- nmz787_i [~ntmccork@134.134.139.83] has joined ##hplusroadmap 22:48 -!- esmerelda [~mabel@2601:602:9603:a3f8:65e5:be41:3c9c:c816] has joined ##hplusroadmap 22:49 -!- esmerelda [~mabel@2601:602:9603:a3f8:65e5:be41:3c9c:c816] has quit [Changing host] 22:49 -!- esmerelda [~mabel@unaffiliated/jacco] has joined ##hplusroadmap 23:23 -!- nmz787_i [~ntmccork@134.134.139.83] has quit [Quit: Leaving.] --- Log closed Tue Apr 11 00:00:23 2017