--- Log opened Fri Apr 28 00:00:38 2017 00:02 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 260 seconds] 00:10 -!- CRM114 [~urchin@unaffiliated/urchin] has quit [Ping timeout: 260 seconds] 00:13 -!- darsie [~darsie@84.113.55.42] has quit [Ping timeout: 240 seconds] 00:25 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has quit [Remote host closed the connection] 01:00 -!- augur [~augur@2601:640:8001:4222:8d46:a115:c969:9644] has joined ##hplusroadmap 01:04 -!- razzy [~razzy@labka.stud.slu.cz] has joined ##hplusroadmap 01:10 < kanzure> didn't know scurvy was based on so few people, that's cool. 01:17 -!- augur [~augur@2601:640:8001:4222:8d46:a115:c969:9644] has quit [Remote host closed the connection] 01:41 -!- Gurkenglas [~Gurkengla@dslb-188-103-222-233.188.103.pools.vodafone-ip.de] has quit [Ping timeout: 260 seconds] 02:06 -!- CRM114 [~urchin@unaffiliated/urchin] has joined ##hplusroadmap 02:11 -!- drewbot [~cinch@54.147.159.3] has quit [Remote host closed the connection] 02:42 -!- drewbot [~cinch@54.226.122.143] has joined ##hplusroadmap 02:49 -!- Jen__ [~Jen@cpc76808-brmb10-2-0-cust571.1-3.cable.virginm.net] has quit [Ping timeout: 240 seconds] 03:12 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap 03:19 -!- HEx1 [~HEx@hexwab.plus.com] has quit [Remote host closed the connection] 04:07 -!- jtimon [~quassel@9.31.134.37.dynamic.jazztel.es] has joined ##hplusroadmap 05:08 -!- Gurkenglas [~Gurkengla@dslb-188-103-222-233.188.103.pools.vodafone-ip.de] has joined ##hplusroadmap 05:20 -!- pompolic [~A@unaffiliated/pompolic] has quit [Ping timeout: 260 seconds] 05:44 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Quit: Leaving] 05:49 -!- TC [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has joined ##hplusroadmap 05:49 -!- TC is now known as Guest77405 05:52 -!- hehelleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has quit [Ping timeout: 240 seconds] 06:13 < archels_> http://www.theverge.com/2017/4/25/15421734/artificial-womb-fetus-biobag-uterus-lamb-sheep-birth-premie-preterm-infant 06:19 -!- Gurkenglas [~Gurkengla@dslb-188-103-222-233.188.103.pools.vodafone-ip.de] has quit [Ping timeout: 255 seconds] 06:30 < kanzure> you're a few days late on that one 06:35 < archels_> I was on vacation for a couple days 06:35 < archels_> has anything interesting been said about it in the mean time? 06:36 -!- pompolic [~A@unaffiliated/pompolic] has joined ##hplusroadmap 06:38 -!- darsie [~darsie@84-113-55-42.cable.dynamic.surfer.at] has joined ##hplusroadmap 06:45 < kanzure> i pointed out that figure 1 is pretty cool 06:46 -!- JayDugger [~jwdugger@47.185.237.246] has joined ##hplusroadmap 07:01 -!- jenelizabeth [~jenelizab@cpc76808-brmb10-2-0-cust571.1-3.cable.virginm.net] has joined ##hplusroadmap 07:06 < archels_> did you see the movies? 07:06 < kanzure> no 07:08 < archels_> they're in the supplementary 07:12 -!- jcluck [~cluckj@static-98-114-125-87.phlapa.ftas.verizon.net] has joined ##hplusroadmap 07:16 -!- cluckj [~cluckj@static-98-114-125-87.phlapa.ftas.verizon.net] has quit [Ping timeout: 258 seconds] 07:20 -!- Gurkenglas [~Gurkengla@dslb-188-103-222-233.188.103.pools.vodafone-ip.de] has joined ##hplusroadmap 07:43 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap 07:44 -!- jenelizabeth [~jenelizab@cpc76808-brmb10-2-0-cust571.1-3.cable.virginm.net] has quit [Read error: Connection reset by peer] 08:09 -!- nmz787_i [~ntmccork@134.134.137.71] has joined ##hplusroadmap 08:35 -!- HEx1 [~HEx@hexwab.plus.com] has joined ##hplusroadmap 09:12 -!- red-001 [red@gateway/shell/elitebnc/x-yrvhulhazetspetf] has joined ##hplusroadmap 09:12 < red-001> intersting 09:13 < red-001> I didn't think I will find a place this intersting while researching old irc logs 09:15 < kanzure> we deal only in exponentially and/or logarithmically mad science 09:18 < red-001> well the person that caused me to search through the logs in question definitely qualifies as mad 09:18 < nmz787_i> backlink? 09:18 < red-001> so I guess I'm in the right place 09:18 < kanzure> which person? 09:18 < red-001> they go by the nick of OldCoder 09:18 < kanzure> oh, yeah i banned him 09:19 < red-001> he is a bit doxxy 09:19 < kanzure> not worth our time really 09:19 < red-001> wow 09:19 < red-001> well I approve 09:20 < red-001> what's nootropic? 09:21 < red-001> I heard of all the other things in the topic 09:21 < kanzure> drugs that improve memory, intelligence. 09:21 < red-001> oh 09:21 < red-001> didn't know there was a special name for them 09:23 < red-001> well this place sounds intersting 09:24 < kanzure> what is your backgroud? 09:24 < kanzure> .. background 09:25 < red-001> what do you mean by that? 09:25 < red-001> as in education? 09:25 < kanzure> skills, super powers, areas of mad science that you specialize in 09:27 < red-001> ehh I guess considering how society would react to post scarcity 09:30 < nmz787_i> aren't we already in post-scarcity for a while? I mean, at this point it is tribalism limiting all humans/sentient-beings from sharing the wealth 09:32 < red-001> I don't think we are quite there 09:32 < red-001> maybe in 15 years 09:32 < red-001> or 10 09:37 < nmz787_i> what is still scarce? 09:38 < TMA> nmz787_i: time and human attention 09:39 < fenn> there's plenty of time and attention being wasted 09:39 < TMA> fenn: which makes the rest scarce 09:41 < gnusha_> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=e0d9b071 Bryan Bishop: some stuff about CHRM2 and ALDH5A1 SSADH >> http://diyhpl.us/diyhpluswiki/genetic-modifications/ 09:49 < red-001> well we still depend on oil,gas,coal,etc 09:50 < kanzure> red-001: here is a thing, http://diyhpl.us/wiki/transcripts/2017-01-26-george-church/ 09:51 < red-001> what do you think of alternative nuclear reactors/fuels? 09:53 < kanzure> fenn: i think hplusroadmap is 10 years old this year? 10:07 < kanzure> "A computer program for simulating time travel and a possible 'solution' for the grandfather paradox" https://arxiv.org/abs/1609.08470 10:09 -!- jtimon [~quassel@9.31.134.37.dynamic.jazztel.es] has quit [Remote host closed the connection] 10:14 < jcluck> the next version of human needs to not have pollen allergies 10:14 -!- jcluck is now known as cluckj 10:23 < kanzure> "A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility" http://www.nature.com/ng/journal/v45/n8/full/ng.2686.html 10:23 < kanzure> "We identified 16 shared susceptibility loci with association P < 5 x 10-8, including 8 loci previously associated with asthma, as well as 4p14 near TLR1, TLR6 and TLR10 (rs2101521, P = 5.3 x 10-21); 6p21.33 near HLA-C and MICA (rs9266772, P = 3.2 x 10-12); 5p13.1 near PTGER4 (rs7720838, P = 8.2 x 10-11); 2q33.1 in PLCL1 (rs10497813, P = 6.1 x 10-10), 3q28 in LPP (rs9860547, P =... 10:23 < kanzure> ... 1.2 x 10-9); 20q13.2 in NFATC2 (rs6021270, P = 6.9 x 10-9), 4q27 in ADAD1 (rs17388568, P = 3.9 x 10-8); and 14q21.1 near FOXA1 and TTC6 (rs1998359, P = 4.8 x 10-8). We identified one locus with substantial evidence of differences in effects across allergies at 6p21.32 in the class II human leukocyte antigen (HLA) region (rs17533090, P = 1.7 x 10-12), which was strongly associat... 10:24 < kanzure> ...ed with cat allergy." 10:25 < cluckj> taking cat allergy off my plate would at least be an improvement 10:27 < gnusha_> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=f2d4e6be Bryan Bishop: some anti-allergy stuff >> http://diyhpl.us/diyhpluswiki/genetic-modifications/ 10:58 < nmz787_i> red-001: I'd say 'depend' is more like 'greedy dudes milking all the value from it' 10:58 < nmz787_i> cluckj: that seems a non-issue in some branches/forks... I am pretty much allergy-free 10:59 < nmz787_i> backporting is always a PITA 10:59 < cluckj> the version control system is super fucked up 11:02 < nmz787_i> data retention is an issue too, it is really hard to unarchive old commits after they've expired 11:02 < cluckj> hah 11:03 < kanzure> you going to start practicing continuous delivery? 11:04 -!- Gurkenglas [~Gurkengla@dslb-188-103-222-233.188.103.pools.vodafone-ip.de] has quit [Ping timeout: 260 seconds] 11:07 < Iriez> Anyone here ever mess with BCP-157, TB-500 or any other peptides? Im trying to figure out a conversion and the calculator is not making sense to my layman brain. The numbers seem wildly inaccurate. 11:08 < cluckj> I think my wife might object? 11:10 < kanzure> if she wants to be first, then that's fine. 11:17 < nmz787_i> kanzure: hmm, I'd need more build agents 11:18 < nmz787_i> I have been thinking of a microfluidic condom though... fwiw, in-line modification 11:18 < kanzure> DIY kit + turkey blaster 11:19 < nmz787_i> my go-to saying is: too much transfer loss 11:42 -!- esmerelda [~mabel@2601:602:9603:a3f8:65e5:be41:3c9c:c816] has quit [Ping timeout: 260 seconds] 11:43 -!- esmerelda [~mabel@2601:602:9603:a3f8:65e5:be41:3c9c:c816] has joined ##hplusroadmap 11:44 -!- Solgriffin [~Sol@c-69-141-24-242.hsd1.nj.comcast.net] has quit [Read error: Connection reset by peer] 11:45 -!- _Sol_ [~Sol@c-69-141-24-242.hsd1.nj.comcast.net] has joined ##hplusroadmap 11:46 -!- _Sol_ is now known as Solgriffin 12:00 -!- red-001 is now known as red-002 12:06 -!- cluckj [~cluckj@static-98-114-125-87.phlapa.ftas.verizon.net] has quit [Ping timeout: 260 seconds] 12:52 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has joined ##hplusroadmap 13:12 -!- Gurkenglas [~Gurkengla@dslb-188-103-222-233.188.103.pools.vodafone-ip.de] has joined ##hplusroadmap 13:16 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has joined ##hplusroadmap 13:39 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Quit: Leaving] 13:47 -!- cluckj [~cluckj@static-98-114-125-87.phlapa.ftas.verizon.net] has joined ##hplusroadmap 13:47 < kanzure> what about irculating membrane-permeable antibodies/ligands/aptamers that connect to each other, to make the synaptic barcodes actually connect with each other on a chemical level? 13:47 < kanzure> *circulating 13:47 < kanzure> and then you use some sort of clearing protocol and pumping action to permeate the cerebral tissue 13:48 < kanzure> (or i might be misunderstanding precisely which step is broken in their procedure) 13:49 < kanzure> with the right membrane permeable ligation technique, you don't really care which barcodes get ligated to each other because you know that the diffusion of barcodes to neighboring cells has a fast drop off.. or something. 14:51 -!- nmz787_i1 [~ntmccork@134.134.137.71] has joined ##hplusroadmap 14:51 -!- nmz787_i [~ntmccork@134.134.137.71] has quit [Remote host closed the connection] 14:58 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has quit [Remote host closed the connection] 15:37 < kanzure> .title https://www.youtube.com/watch?v=u5V_VzRrSBI 15:37 < yoleaux> The Boring Company | Tunnels - YouTube 15:53 -!- augur [~augur@74-95-6-5-SFBA.hfc.comcastbusiness.net] has joined ##hplusroadmap 15:55 -!- Gurkenglas [~Gurkengla@dslb-188-103-222-233.188.103.pools.vodafone-ip.de] has quit [Ping timeout: 240 seconds] 17:00 -!- streety [streety@2a01:7e00::f03c:91ff:feae:ded6] has quit [Quit: ZNC - http://znc.in] 17:05 < kanzure> hmph 17:08 < kanzure> http://simbad.u-strasbg.fr/simbad/sim-id?Ident=HIP+4436 17:08 < kanzure> http://simbad.u-strasbg.fr/simbad/sim-id?Ident=HIP+99427 17:09 < kanzure> http://simbad.u-strasbg.fr/simbad/sim-id?Ident=HIP+65352 17:10 < kanzure> er, or HIP45493 17:17 -!- augur [~augur@74-95-6-5-SFBA.hfc.comcastbusiness.net] has quit [Remote host closed the connection] 17:19 < kanzure> andytoshi: btw adlai is also studying chemistry 17:32 < nmz787_i1> you and your Boring content, kanzure 17:32 < nmz787_i1> .wik boring, OR 17:32 < yoleaux> "Boring is an unincorporated community in Clackamas County, Oregon, United States. It is located along Oregon Route 212 in the foothills of the Cascade mountain range, approximately twelve miles (19 km) southeast of Portland. The Boring Lava Field, which lies between Portland and Boring, took its namesake after the town." -- https://en.wikipedia.org/wiki/Boring,_OR 17:32 < nmz787_i1> .wik Boring Lava 17:32 < yoleaux> "The Boring Lava Field is an extinct Plio-Pleistocene volcanic field zone with at least 32 cinder cones and small shield volcanoes lying within a radius of 13 miles (21 km) of Kelly Butte, which is approximately 4 miles (6 km) east of downtown Portland, Oregon, in the United States." -- https://en.wikipedia.org/wiki/Boring_Lava_Field 17:33 < nmz787_i1> .g who discovered Boring Lava Field 17:33 < yoleaux> https://en.wikipedia.org/wiki/Boring_Lava_Field 17:33 < nmz787_i1> pfft 17:34 < nmz787_i1> "The densest concentration of volcanic vents lies west of the town of Boring, where 20 centers occur within an area of about 36 square miles. Because of this grouping near Boring, Ray Treasher (1942) first gave the name "Boring lava" to the lava, cinders, and ash which emanated from volcanic centers in the Portland area within a time span of from perhaps 10 mi Ilion to less than 1 mi Ilion years ago (Trimble, 1963)." 17:34 < nmz787_i1> so it wasn't some Boring guy 17:51 -!- streety [streety@2a01:7e00::f03c:91ff:feae:ded6] has joined ##hplusroadmap 17:53 -!- Proteus [~Proteus@unaffiliated/proteus] has quit [Quit: Leaving.] 17:54 -!- Proteus [~Proteus@unaffiliated/proteus] has joined ##hplusroadmap 17:55 -!- Proteus [~Proteus@unaffiliated/proteus] has quit [Client Quit] 17:56 -!- Proteus [~Proteus@unaffiliated/proteus] has joined ##hplusroadmap 18:22 < kanzure> yashgaroth: would significantly delayed puberty be a viable longevity approach? 18:22 < kanzure> or delayed menopause etc 18:27 < kanzure> nobody has added perfect pitch to the page yet O_o 18:29 < nmz787_i1> kanzure: FIB is back online 18:29 < nmz787_i1> are you still up for it? 18:29 < kanzure> same price? 18:29 < nmz787_i1> yes, jblake was giving me freight shipping tips too, depending on getting it boxed up though 18:30 < nmz787_i1> I also learned, though, that the seller doesn't have a forklift... but also jblake found it a bit hard to believe that one unit weighed 5000lbs 18:31 < kanzure> are you going to have to travel to go box it up? 18:31 < nmz787_i1> I haven't priced forklift rental on either end yet 18:31 < nmz787_i1> that was one idea... 18:56 -!- darsie [~darsie@84-113-55-42.cable.dynamic.surfer.at] has quit [Ping timeout: 255 seconds] 19:09 -!- cevi_ [~zeb@128.12.245.10] has joined ##hplusroadmap 19:09 -!- cevi__ [~zeb@128.12.245.10] has quit [Read error: Connection reset by peer] 19:22 -!- CRM114 [~urchin@unaffiliated/urchin] has quit [Remote host closed the connection] 19:47 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has joined ##hplusroadmap 19:47 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has quit [Remote host closed the connection] 19:49 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has joined ##hplusroadmap 20:05 < kanzure> various people complaining about drilling machines https://news.ycombinator.com/item?id=14223020 20:32 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has quit [Quit: Leaving...] 20:32 < kanzure> beep 21:08 < nmz787_i1> blop 21:54 -!- TinKode [~TinKode@unaffiliated/tinkode] has joined ##hplusroadmap 22:47 -!- UnknownRogue [~UnknownRo@173.209.53.237] has joined ##hplusroadmap 23:13 -!- UnknownRogue [~UnknownRo@173.209.53.237] has quit [Quit: Leaving] 23:26 < justanotheruser> where do I get single piezotubes these days 23:58 -!- sbodin [~sbodin@91.226.141.251] has joined ##hplusroadmap --- Log closed Sat Apr 29 00:00:39 2017