--- Log opened Tue May 02 00:00:42 2017 00:35 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has quit [Remote host closed the connection] 01:02 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 01:41 -!- Jen__ [~Jen@cpc76808-brmb10-2-0-cust571.1-3.cable.virginm.net] has quit [Ping timeout: 260 seconds] 01:54 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 276 seconds] 02:14 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 02:34 -!- Regex [~Cara@2601:1c0:8500:5edb:a4e4:10bb:577b:475c] has quit [Ping timeout: 260 seconds] 02:37 -!- Regex [~Cara@c-50-188-176-150.hsd1.or.comcast.net] has joined ##hplusroadmap 02:43 -!- nickjohnson [sid789@gateway/web/irccloud.com/x-ajqnhxlliknggcjo] has quit [Read error: Connection reset by peer] 02:44 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap 02:45 -!- nickjohnson [sid789@gateway/web/irccloud.com/x-ccbzbxapdldgkpil] has joined ##hplusroadmap 02:47 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 240 seconds] 03:05 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 03:43 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 264 seconds] 04:02 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 04:13 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 260 seconds] 04:27 -!- drewbot [~cinch@54.224.165.8] has quit [Remote host closed the connection] 04:32 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 04:39 -!- andytoshi [~apoelstra@unaffiliated/andytoshi] has quit [Ping timeout: 240 seconds] 04:41 -!- andytoshi [~apoelstra@wpsoftware.net] has joined ##hplusroadmap 05:01 < anthk_> hello, I've seen a video from a guy talking about transhumanism, taking vitamin suplemments in order to tweak itself so it could learn math and H+ engineering faster. 05:01 < anthk_> Anyone have seen it? I can't remember the URL 05:07 < archels_> Ray Kurzweil? 05:16 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 260 seconds] 05:17 < kanzure> archels_: pffft. banned. 05:17 < kanzure> nmz787_: so you can definitely move it to your place? 05:29 -!- drewbot [~cinch@54.80.228.16] has joined ##hplusroadmap 05:30 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap 05:31 < archels_> heh 05:42 -!- Gurkenglas [~Gurkengla@dslb-188-103-222-233.188.103.pools.vodafone-ip.de] has joined ##hplusroadmap 05:50 -!- hehelleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has joined ##hplusroadmap 05:53 -!- helleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has quit [Ping timeout: 260 seconds] 06:00 < kanzure> anthk_: vitamin supplements aren't going to significantly improve your ability to do engineering 06:00 < kanzure> unless you have a weird mutation or you're extremely deficient 06:07 < anthk_> it was a guy with a monk-like spirit 06:08 < anthk_> it monitorized even the stress levels and reading speed 06:08 < anthk_> I think it was a CEO of a H+ company, I can't remember 06:13 < kanzure> anthk_: i judge you as guilty of cheerleading; your punishment is to read everything in http:/diyhpl.us/~bryan/papers2/neuro/ 06:14 < anthk_> I know what H+ is, I don't think that was H+, but I was interested on the behaviour to improve the self so you can learn on H+ faster 06:14 < kanzure> if you wish to appeal, you should do so immediately 06:15 < anthk_> not related to H+, I am currently with linaer algebra so I can understand neural networks 06:16 < kanzure> then you should read these http://diyhpl.us/~bryan/papers2/ai/machine-learning/ 06:17 < anthk_> thanks kanzure 06:28 < adlai> speaking of things that don't really help, but give you the warm H+ fuzzies: what do yous think of 'brain training'? eg dual N-back 06:31 < adlai> (my guess is that even if it doesn't actually improve performance, it's still valuable to have a handle on degradation) 06:34 < kanzure> that's gwern territory, meh 06:36 < adlai> indeed, it's through him that i'm familiar with the term of art. before that, DnB was a phonon distribution 06:36 < kanzure> gwern stuff is exceedingly uninteresting. 06:37 < adlai> oh. is this a topical or personal judgement? 06:39 < JayDugger> Hm. 06:39 < kanzure> well he's completely evil, https://news.ycombinator.com/item?id=10702001 06:41 < adlai> ah so he's meta-ignorant, that's too bad. (ignorant about his own areas ignorance) 06:41 < kanzure> no, it's worse 06:41 < kanzure> http://diyhpl.us/~bryan/more-anti-gwern.txt 06:42 < kanzure> he literally published something that he *knew* was wrong 06:45 < adlai> oh well. i guess he's another H- after all 06:46 < kanzure> yep. anyway... 06:51 < adlai> in other Kurzweil: https://www.youtube.com/watch?v=X4Neivqp2K4 (music) 06:52 < kanzure> https://www.youtube.com/watch?v=6hKG5l_TDU8 06:57 * adlai can't figure out whether the singularity is a good or bad thing [in the mind of this last music] 07:08 -!- OfficialJustan [~justanoth@unaffiliated/justanotheruser] has quit [Ping timeout: 260 seconds] 07:20 < kanzure> adlai: were you around for when the conspiracy nut was in here claiming that i was going to take over the world and forcefully upload everyone and torture them for eternity? 07:22 < adlai> iirc no, but you've mentioned it before. it smells of some "pascal's basilisk" confusion. 07:25 < kanzure> good times. 07:26 < kanzure> it's too bad that rbtc hasn't picked up on that to incorporate it into their broader conspiracies 07:30 < adlai> never too late to shill "against" yourself (the sooner they see the prepostrosity of such conspiracies, the sooner they realize there may be footprints on the moon after all) 07:30 < adlai> although life is probably too short to educate the internet. 07:41 -!- Burnin8 [~Burn@pool-108-18-203-134.washdc.fios.verizon.net] has joined ##hplusroadmap 07:43 -!- Aurelius [~cpopell@50.35.79.117] has quit [Ping timeout: 255 seconds] 07:43 -!- nanotube [~nanotube@unaffiliated/nanotube] has quit [Ping timeout: 240 seconds] 07:43 -!- pent [~pent@138.197.129.246] has quit [Ping timeout: 240 seconds] 07:44 -!- drewbot [~cinch@54.80.228.16] has quit [Ping timeout: 240 seconds] 07:44 -!- Burninate [~Burn@pool-108-18-203-134.washdc.fios.verizon.net] has quit [Ping timeout: 255 seconds] 07:44 -!- red-002 [red@gateway/shell/elitebnc/x-yrvhulhazetspetf] has quit [Ping timeout: 255 seconds] 07:45 -!- balrog [~balrog@unaffiliated/balrog] has quit [Ping timeout: 240 seconds] 07:46 -!- pent [~pent@138.197.129.246] has joined ##hplusroadmap 07:46 -!- pompolic [~A@unaffiliated/pompolic] has quit [Remote host closed the connection] 07:46 -!- pompolic [~A@unaffiliated/pompolic] has joined ##hplusroadmap 07:47 -!- fenn [~fenn@unaffiliated/fenn] has quit [Ping timeout: 255 seconds] 07:48 -!- fenn [~fenn@unaffiliated/fenn] has joined ##hplusroadmap 07:50 -!- balrog [~balrog@unaffiliated/balrog] has joined ##hplusroadmap 07:51 -!- Aurelius [~cpopell@50.35.79.117] has joined ##hplusroadmap 07:54 -!- thundara [~thundara@104.236.109.149] has quit [Ping timeout: 264 seconds] 07:55 < chris_99> just saw https://hackaday.io/project/20812-make-water-collaborative-water-purification never heard of electrocoagulation before 07:55 -!- thundara [~thundara@104.236.109.149] has joined ##hplusroadmap 07:58 -!- nanotube [~nanotube@unaffiliated/nanotube] has joined ##hplusroadmap 07:59 -!- red-001 [red@gateway/shell/elitebnc/x-npzzzuwliafieqbu] has joined ##hplusroadmap 08:11 -!- CRM114 [~urchin@unaffiliated/urchin] has quit [Ping timeout: 260 seconds] 08:26 < archels_> the 3D printed thread works ^_^ 08:27 < archels_> radius tolerance = 0.2 mm, thread width = 0.5 mm, thread height chosen such it tapers into an equilateral triangle 08:30 < archels_> http://imgur.com/a/9svTm 08:33 < kanzure> whatcha up to 08:35 < FourFire> kanzure, some dude is trying to organize the people from that longevity community on discord in the direction of doing projects. I've told him about you and this channel, and will invite him when applicable. 08:35 < archels_> a high resolution 3D reconstruction, ultimately 08:36 < archels_> we had to first reverse engineer the thread from the platform though 08:36 < chris_99> neat archels_, was that done with SLA 08:38 < archels_> yeah, it has a rated resolution of 25 microns. the part took 1h15m to print 08:39 -!- JayDugger [~jwdugger@47.185.237.246] has quit [Quit: Leaving.] 08:40 < chris_99> cool, what printer is it that you have? 08:40 < chris_99> i was curious about them, for printing jewellery models, you could make a mould from 08:42 < archels_> it's a Form 1 from FormLabs 08:44 < archels_> hmm, making moulds would be interesting, yeah 08:45 < archels_> would you make a negative cast from the 3D print first, and then use that for the actual final material (e.g. metal)? 08:47 < chris_99> i'm not sure what the technical term is (i dont know what negative cast means) but i'd look like that - http://img.diytrade.com/cdimg/1053110/17915900/0/1293697557/jewellery_rubber_mold_silicone_mould.jpg like you'd pour silicone around it afaik 08:51 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 260 seconds] 08:52 -!- drewbot [~cinch@54.80.228.16] has joined ##hplusroadmap 08:54 < archels_> ah 08:54 < archels_> is it possible to make metal objects this way at all? 08:55 < chris_99> yeah, you pour gold into the mould 09:00 < chris_99> like afaik you would make the rubber mould with the model in, then cut it in half, remove the model, clamp the moulds together, pour gold into the sprue 09:01 < chris_99> for example see - https://youtu.be/ciFnhRk5p_Q?t=109 they're making a mould of an existing ring with a sprue 09:02 -!- augur [~augur@74-95-6-5-SFBA.hfc.comcastbusiness.net] has joined ##hplusroadmap 09:11 < chris_99> hmm maybe i'm wrong, i thought you poured the gold directly into the mould maybe not 09:13 < chris_99> yeah sorry, it seems, you make the mould, then pour some kind of wax in 09:13 < chris_99> and do the lost wax method 09:13 < chris_99> from then 09:15 < chris_99> i'm sure i recall someone using the resin/plastic from a 3d print directly in the lost-wax method, but im not sure how well that works 09:16 < chris_99> http://www.instructables.com/id/From-3d-printed-part-to-metal-the-lost-plaabs-me/ seems it does work 09:19 < archels_> ahh right 09:20 < chris_99> yeah i got it confused, so you either use the 3d print like wax, and let it burnout in the lost-wax method, or you make a mould and create wax models 09:26 -!- nmz787_i [~ntmccork@134.134.139.83] has joined ##hplusroadmap 09:34 < kanzure> human genome project in the news today: http://www.cnbc.com/2017/05/02/synthetic-dna-scientist-says-it-could-be-inside-humans-within-5-years.html 09:36 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Remote host closed the connection] 09:44 < nmz787_i> i've got 4 to 8.5 months of full-time work planned to get to something that seems to be a minimum viable microfluidic DNA synthesizer... worked on it late last night, so didn't get as much thinking done efficiently, so will probably revisit and add more work 09:47 -!- satori__ is now known as satori_ 09:47 < nmz787_i> kanzure: yeah I have somewhere to put it, back corner of my garage. I'd probably push myself to add a new wall or two, and probably a door... so I could have some dust isolation 09:48 < nmz787_i> kanzure: do you have any ideas for it? 09:48 < nmz787_i> using it 09:48 < nmz787_i> kanzure: I want you to get some satisfaction from this purchase, unless you don't need that 09:48 -!- augur [~augur@74-95-6-5-SFBA.hfc.comcastbusiness.net] has quit [Remote host closed the connection] 09:49 < nmz787_i> kanzure: maybe we'll hav eour own HGP protest greet us 09:49 < nmz787_i> that would be... romantic? 09:49 < nmz787_i> the universe playing hard to get 09:49 < kanzure> i don't really have a specific project in mind for a FIB right now 09:53 < kanzure> "Quantitative assessment of timing, efficiency, specificity, and genetic mosaicism of CRISPR/Cas9 mediated gene editing of hemoglobin beta gene in rhesus monkey embryos" https://academic.oup.com/hmg/article-abstract/3746922/Quantitative-assessment-of-timing-efficiency 10:13 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has joined ##hplusroadmap 10:30 -!- cevi_ [~zeb@128.12.245.10] has quit [Ping timeout: 258 seconds] 10:45 -!- cevi_ [~zeb@128.12.245.10] has joined ##hplusroadmap 10:50 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has joined ##hplusroadmap 10:54 -!- strages [uid11297@gateway/web/irccloud.com/x-jclhpngispulvfos] has joined ##hplusroadmap 11:08 < nmz787_i> kanzure: well, if I just need to convince you you click bid, please do so. 11:09 < nmz787_i> kanzure: I also wonder if you bid 1500, will it say 'reserve not met' 11:23 -!- bsm1175321 [~mcelrath@135.84.167.210] has joined ##hplusroadmap 12:19 -!- NikopolSohru [~NSohru@109.202.102.87] has joined ##hplusroadmap 12:26 -!- Madars [~null@unaffiliated/madars] has joined ##hplusroadmap 12:35 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has joined ##hplusroadmap 12:40 -!- NikopolSohru [~NSohru@109.202.102.87] has quit [Quit: Leaving] 12:42 -!- NikopolSohru [~NSohru@109.202.102.87] has joined ##hplusroadmap 12:47 -!- nmz787_i [~ntmccork@134.134.139.83] has quit [Quit: Leaving.] 13:10 -!- cluckj [~cluckj@static-98-114-125-87.phlapa.ftas.verizon.net] has quit [Quit: Leaving] 13:29 -!- Srtagalicia [uid226960@gateway/web/irccloud.com/x-mzfdflsrjuuuzwil] has joined ##hplusroadmap 13:33 -!- NikopolSohru [~NSohru@109.202.102.87] has quit [Quit: Leaving] 13:35 < kanzure> Srtagalicia: hi. 13:36 < Srtagalicia> @kanzure hi, i'm new here so, please, forgive mi mistakes until I learn. 13:45 -!- cluckj [~cluckj@static-98-114-125-87.phlapa.ftas.verizon.net] has joined ##hplusroadmap 14:15 -!- nmz787_i [~ntmccork@134.134.139.83] has joined ##hplusroadmap 14:18 -!- nmz787_i1 [~ntmccork@134.134.139.74] has joined ##hplusroadmap 14:21 -!- nmz787_i [~ntmccork@134.134.139.83] has quit [Ping timeout: 240 seconds] 14:46 < kanzure> "We will be surveying the audience during the meeting. We are asking each presenter to send us one question that they would like us to ask the attendees. Please send this to me by Wednesday, May 3nd." 14:47 -!- nmz787_i1 [~ntmccork@134.134.139.74] has quit [Quit: Leaving.] 14:56 < kanzure> let's say that a certain bird has told me that facebook is willing to put $10M into a mutantpedia--- what projects would you propose? 14:58 -!- nmz787_i [ntmccork@nat/intel/x-elsytkmnmwpmtdwo] has joined ##hplusroadmap 15:01 -!- nmz787_i [ntmccork@nat/intel/x-elsytkmnmwpmtdwo] has left ##hplusroadmap [] 15:08 -!- chris_99 [~chris_99@unaffiliated/chris-99/x-3062929] has quit [Quit: Leaving] 15:38 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 15:48 -!- cacala [uid225747@gateway/web/irccloud.com/x-bdmqrtaotdogmaxt] has quit [Quit: Connection closed for inactivity] 16:03 < kanzure> .title https://news.ycombinator.com/item?id=14248827 16:03 < yoleaux> CRISPR eliminates HIV-1 infection in live animals | Hacker News 16:04 < kanzure> "In vivo exclusion of HIV-1 provirus by saCas9 and multiple sgRNAs in animal models" http://www.sciencedirect.com/science/article/pii/S1525001617301107 16:04 < kanzure> https://www.ll.mit.edu/news/DRACO.html 16:04 < kanzure> http://www.businessinsider.com/todd-rider-draco-crowdfunding-broad-spectrum-antiviral-2015-12 16:05 < kanzure> https://www.indiegogo.com/projects/dracos-may-be-effective-against-all-viruses#/ 16:05 < cluckj> paying someone to make the basic structure usable? 16:08 < kanzure> hm? 16:19 -!- Gurkenglas [~Gurkengla@dslb-188-103-222-233.188.103.pools.vodafone-ip.de] has quit [Ping timeout: 276 seconds] 16:34 -!- strages [uid11297@gateway/web/irccloud.com/x-jclhpngispulvfos] has quit [Quit: Connection closed for inactivity] 17:15 < cluckj> for mutantpedia 17:39 < kanzure> cluckj: well, i was thinking more like, "facebook should look at likely sleep data and figure out families that have interesting sleep superpowers, and then send 23andme kits/other genotyping services/genome sequencing" 17:40 < cluckj> oh 17:40 < kanzure> or, "facebook should put genotyping services near the front gates of music concerts and have users do a sample plus link up their facebook account for future questions" 17:41 < kanzure> or, "let users opt-in and do free form answers to survey questions, then do analysis on their typed answers, to correlate their phenotypes to their genotypes" 17:41 < kanzure> or even better: have friends type up interesting phenotype information about their friends 17:51 < cluckj> those don't sound evil enough 17:54 -!- night is now known as night|pub 18:20 -!- darsie [~darsie@84-113-55-42.cable.dynamic.surfer.at] has quit [Ping timeout: 276 seconds] 18:21 < kanzure> why does it have to be evil 18:31 < cluckj> they do creepy research on users? 18:31 < cluckj> what about colorblindness genes? 18:32 -!- night|pub is now known as night 18:34 < cluckj> that's a relatively easy phenotype to test for on a computer (not that folks wouldn't already know) 18:45 < cluckj> the evil version I'm thinking of could be something like "comb user data for signs of depression and send them a testing kit to match genotypes to phenotypes" 19:05 -!- balrog [~balrog@unaffiliated/balrog] has quit [Quit: Bye] 19:08 -!- yashgaroth [~yashgarot@2606:6000:cd4d:3300:f5e0:f867:a11d:8d52] has joined ##hplusroadmap 19:14 -!- balrog [~balrog@unaffiliated/balrog] has joined ##hplusroadmap 19:52 -!- ExeciN [ExeciN@bnc.stormbit.net] has quit [Excess Flood] 19:57 -!- ExeciN [ExeciN@bnc.stormbit.net] has joined ##hplusroadmap 20:01 < gnusha_> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=6b948c21 Bryan Bishop: transcript: confidential transactions (gmaxwell) >> http://diyhpl.us/diyhpluswiki/transcripts/gmaxwell-confidential-transactions/ 20:04 < gnusha_> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=81096c42 Bryan Bishop: tweeter link >> http://diyhpl.us/diyhpluswiki/transcripts/gmaxwell-confidential-transactions/ 20:05 < kanzure> http://diyhpl.us/wiki/transcripts/gmaxwell-confidential-transactions/ 20:12 < gnusha_> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=5dbc4aa9 Bryan Bishop: more links >> http://diyhpl.us/diyhpluswiki/transcripts/gmaxwell-confidential-transactions/ 20:17 -!- augur [~augur@noisebridge130.static.monkeybrains.net] has quit [Ping timeout: 264 seconds] 20:43 -!- augur [~augur@104.236.181.226] has joined ##hplusroadmap 20:48 -!- preview [~preview@103.23.18.14] has joined ##hplusroadmap 20:54 -!- UnknownRogue [~UnknownRo@184.75.213.37] has joined ##hplusroadmap 21:00 -!- UnknownRogue [~UnknownRo@184.75.213.37] has quit [Quit: Leaving] 21:19 -!- preview [~preview@103.23.18.14] has quit [Ping timeout: 240 seconds] 21:25 -!- augur [~augur@104.236.181.226] has quit [Read error: Connection reset by peer] 21:25 -!- augur [~augur@104.236.181.226] has joined ##hplusroadmap 21:28 -!- augur [~augur@104.236.181.226] has quit [Read error: Connection reset by peer] 21:29 -!- augur [~augur@104.236.181.226] has joined ##hplusroadmap 21:32 -!- augur [~augur@104.236.181.226] has quit [Read error: Connection reset by peer] 21:33 -!- augur [~augur@104.236.181.226] has joined ##hplusroadmap 21:34 -!- augur [~augur@104.236.181.226] has quit [Read error: Connection reset by peer] 21:41 -!- augur [~augur@104.236.181.226] has joined ##hplusroadmap 21:46 -!- augur [~augur@104.236.181.226] has quit [Read error: Connection reset by peer] 21:53 -!- preview [~preview@cbdfree-gw.cbdfree.net.nz] has joined ##hplusroadmap 21:55 -!- ExeciN [ExeciN@bnc.stormbit.net] has quit [Excess Flood] 22:00 -!- ExeciN [ExeciN@bnc.stormbit.net] has joined ##hplusroadmap 22:16 -!- esmerelda [~mabel@2601:602:9603:a3f8:65e5:be41:3c9c:c816] has quit [Ping timeout: 255 seconds] 22:16 -!- esmerelda [~mabel@2601:602:9603:a3f8:65e5:be41:3c9c:c816] has joined ##hplusroadmap 22:26 -!- preview [~preview@cbdfree-gw.cbdfree.net.nz] has quit [Remote host closed the connection] 22:28 -!- preview [~preview@cbdfree-gw.cbdfree.net.nz] has joined ##hplusroadmap 22:29 -!- Guest14972 [~augur@104.236.181.226] has joined ##hplusroadmap 22:33 -!- yashgaroth [~yashgarot@2606:6000:cd4d:3300:f5e0:f867:a11d:8d52] has quit [Quit: Leaving] 22:34 -!- preview [~preview@cbdfree-gw.cbdfree.net.nz] has quit [Ping timeout: 260 seconds] 22:48 -!- preview [~preview@cbdfree-gw.cbdfree.net.nz] has joined ##hplusroadmap 22:52 -!- Guest14972 [~augur@104.236.181.226] has quit [Remote host closed the connection] 23:28 -!- augur [~augur@104.236.181.226] has joined ##hplusroadmap 23:31 -!- preview [~preview@cbdfree-gw.cbdfree.net.nz] has quit [Ping timeout: 276 seconds] 23:40 -!- augur [~augur@104.236.181.226] has quit [Ping timeout: 240 seconds] --- Log closed Wed May 03 00:00:43 2017