--- Log opened Mon Nov 06 00:00:07 2017
00:03 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Remote host closed the connection]
00:15 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap
00:29 < razzy> nmz787: fltrz nature channel, history chanel, basic radio plays :] that what i will use to bootstrap my child :]
00:43 < razzy> fltrz: there should be games or gamified education SW for children already :]
00:45 < fltrz> yes, but I suspect the reward is often hardcoded, I wonder if there is some standard API for educational software so that it can for example unlock the computer or a specific application
00:55 -!- Gurkenglas [~Gurkengla@dslb-094-223-138-157.094.223.pools.vodafone-ip.de] has joined ##hplusroadmap
01:07 < razzy> hmm, i like the way you think guys :].
01:14 -!- entity8421[m] [entity8421@gateway/shell/matrix.org/x-oxzzyoepttmwvneg] has joined ##hplusroadmap
01:15 -!- Gurkenglas [~Gurkengla@dslb-094-223-138-157.094.223.pools.vodafone-ip.de] has quit [Ping timeout: 240 seconds]
01:26 -!- Rmesil8O4b[m] [rmesil8o4b@gateway/shell/matrix.org/x-toijduwbuemytili] has joined ##hplusroadmap
01:35 -!- CRM114 [~urchin@unaffiliated/urchin] has joined ##hplusroadmap
01:37 -!- entity8421[m] [entity8421@gateway/shell/matrix.org/x-oxzzyoepttmwvneg] has quit [Read error: Connection reset by peer]
01:37 -!- Rmesil8O4b[m] [rmesil8o4b@gateway/shell/matrix.org/x-toijduwbuemytili] has quit [Read error: Connection reset by peer]
01:42 -!- entity8421[m] [entity8421@gateway/shell/matrix.org/x-veefujqctnkrxisi] has joined ##hplusroadmap
01:55 -!- Rmesil8O4b[m] [rmesil8o4b@gateway/shell/matrix.org/x-nqwsvtevzdijevau] has joined ##hplusroadmap
02:22 <@fenn> sign language seems a lot more useful than requiring a tablet with a specific app running on it in order to communicate
02:23 <@fenn> need a sign for 'bored'
02:24 <@fenn> you could teach the tablet sign language with its camera
02:28 <@fenn> i'd suggest adding chinese to the baby curriculum, since apparently phoneme discrimination is difficult to learn later on
02:30 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has quit [Ping timeout: 248 seconds]
03:04 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 252 seconds]
03:07 -!- darsie [~username@84-114-73-160.cable.dynamic.surfer.at] has joined ##hplusroadmap
03:20 -!- CRM114 [~urchin@unaffiliated/urchin] has quit [Remote host closed the connection]
03:40 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap
04:13 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Remote host closed the connection]
04:16 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap
05:08 -!- ebowden [~ebowden@2001:8003:1074:bc00:84fc:dd5f:edc6:8c6d] has quit [Read error: Connection reset by peer]
05:09 -!- ebowden [~ebowden@2001:8003:1074:bc00:f04e:826:1331:20e] has joined ##hplusroadmap
05:23 -!- y0no [y0no@2001:bc8:212d:201:ff01::a] has quit [Ping timeout: 255 seconds]
05:23 -!- Joshchamp [sid159459@gateway/web/irccloud.com/x-ihevruavhnvrzfoa] has quit [Read error: Connection reset by peer]
05:23 -!- Joshchamp [sid159459@gateway/web/irccloud.com/x-zytqmkpnrvegebql] has joined ##hplusroadmap
05:24 -!- y0no [y0no@2001:bc8:212d:201:ff01::a] has joined ##hplusroadmap
05:24 -!- strages [uid11297@gateway/web/irccloud.com/x-lbickohcsinzklhk] has quit [Ping timeout: 255 seconds]
05:45 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Remote host closed the connection]
05:48 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap
05:54 -!- hehelleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has joined ##hplusroadmap
05:57 -!- helleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has quit [Ping timeout: 248 seconds]
06:03 -!- mindsForge [~nak@174-26-123-39.phnx.qwest.net] has joined ##hplusroadmap
06:30 -!- WeirdTolkienishF [~Weird@204.48.46.11] has joined ##hplusroadmap
06:30 -!- WeirdTolkienishF [~Weird@204.48.46.11] has quit [Changing host]
06:30 -!- WeirdTolkienishF [~Weird@unaffiliated/weirdtolkienishf] has joined ##hplusroadmap
06:53 < kanzure> well ok
06:56 -!- aeiousomething [~aeiousome@gateway/vpn/privateinternetaccess/aeiousomething] has quit [Ping timeout: 268 seconds]
07:20 -!- strages [uid11297@gateway/web/irccloud.com/x-oomwdexaprotfuui] has joined ##hplusroadmap
07:30 -!- bluebear_ [~dluhos@80.95.97.194] has joined ##hplusroadmap
07:55 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has joined ##hplusroadmap
08:02 -!- CheckDavid [uid14990@gateway/web/irccloud.com/x-nikaqhklcyamokog] has joined ##hplusroadmap
08:08 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Quit: Leaving.]
08:17 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap
08:19 -!- rpifan [~rpifan@207-244-191-189-dhcp.mia.fl.atlanticbb.net] has joined ##hplusroadmap
08:24 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Quit: Leaving.]
08:24 -!- aeiousomething [~aeiousome@gateway/vpn/privateinternetaccess/aeiousomething] has joined ##hplusroadmap
08:33 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has quit [Ping timeout: 255 seconds]
09:07 < heath> aha, this is why they took the video down. they wanted to make it into a news item
09:07 < heath> https://wyss.harvard.edu/autonomously-growing-synthetic-dna-strands/
09:07 < heath> i had just sent her an email yesterday morning about the video
09:18 -!- ebowden [~ebowden@2001:8003:1074:bc00:f04e:826:1331:20e] has quit [Read error: Connection reset by peer]
09:19 -!- ebowden [~ebowden@110.141.11.39] has joined ##hplusroadmap
09:47 < nmz787> fenn: bored is a good extra symbol/meme to add to sign-language training
09:49 < heath> .title https://www.theregister.co.uk/2017/10/18/storing_data_in_monomers_read_through_mass_spectroscopy/
09:49 < yoleaux> heath: Sorry, that doesn't appear to be an HTML page.
09:50 < heath> "DNA as storage? Old and boring. Boffins now chaining monomers"
10:35 -!- rpifan [~rpifan@207-244-191-189-dhcp.mia.fl.atlanticbb.net] has quit [Ping timeout: 260 seconds]
10:39 -!- juri_ [~juri@205.166.94.162] has quit [Ping timeout: 252 seconds]
10:44 -!- mindsForge [~nak@174-26-123-39.phnx.qwest.net] has quit [Quit: Leaving.]
10:46 -!- juri_ [~juri@205.166.94.162] has joined ##hplusroadmap
10:47 -!- NikopolSohru [~NSohru@5.79.76.37] has joined ##hplusroadmap
10:52 -!- NikopolSohru [~NSohru@5.79.76.37] has quit [Remote host closed the connection]
11:04 -!- bluebear_ [~dluhos@80.95.97.194] has quit [Quit: Leaving.]
11:30 -!- WeirdTolkienishF [~Weird@unaffiliated/weirdtolkienishf] has quit [Read error: Connection reset by peer]
11:34 -!- shiv_ [~shiv@2405:205:b00e:39c0:75a7:b42f:9bcf:d8b1] has joined ##hplusroadmap
11:34 < shiv_> hi
11:34 < shiv_> anyone online ?
11:34 < shiv_> need help with nootropics!
11:38 -!- shiv_ is now known as kiddin
11:44 -!- kiddin [~shiv@2405:205:b00e:39c0:75a7:b42f:9bcf:d8b1] has quit [Quit: Leaving]
12:14 -!- Rmesil8O4b[m] [rmesil8o4b@gateway/shell/matrix.org/x-nqwsvtevzdijevau] has quit [Ping timeout: 240 seconds]
12:15 -!- entity8421[m] [entity8421@gateway/shell/matrix.org/x-veefujqctnkrxisi] has quit [Ping timeout: 276 seconds]
12:17 -!- CheckDavid [uid14990@gateway/web/irccloud.com/x-nikaqhklcyamokog] has quit [Quit: Connection closed for inactivity]
12:50 < superkuh> https://torrentfreak.com/us-court-grants-isps-and-search-engine-blockade-of-sci-hub-171106/
13:12 -!- aeiousomething [~aeiousome@gateway/vpn/privateinternetaccess/aeiousomething] has quit [Ping timeout: 250 seconds]
13:34 < nmz787> streety posted this a year+ ago... but seems worth it to re-post http://collections.plos.org/open-source-toolkit-hardware/
13:34 < nmz787> .title
13:34 < yoleaux> PLOS Collections: Article collections published by the Public Library of Science
13:37 < nmz787> "It’s clear that the affected Internet services will not be happy with the outcome."  seems like they'd be all welcoming about this, to me, actually... so they can get into the pockets of the publishers and anyone else who has money at stake which they hope to protect via DRM or making pirated data unable to obtain
13:38 < nmz787> "Also, the site has a Tor version which can’t be blocked by Internet providers, so determined scientists will still be able to access the site if they want."
13:38 < nmz787> well that's good
13:58 -!- entity8421[m] [entity8421@gateway/shell/matrix.org/x-ctaykbtqzminlmjz] has joined ##hplusroadmap
14:10 -!- Rmesil8O4b[m] [rmesil8o4b@gateway/shell/matrix.org/x-brccgsbjnlwpauuj] has joined ##hplusroadmap
14:41 -!- jtimon [~quassel@164.31.134.37.dynamic.jazztel.es] has joined ##hplusroadmap
15:00 -!- Rmesil8O4b[m] [rmesil8o4b@gateway/shell/matrix.org/x-brccgsbjnlwpauuj] has quit [Remote host closed the connection]
15:00 -!- entity8421[m] [entity8421@gateway/shell/matrix.org/x-ctaykbtqzminlmjz] has quit [Read error: Connection reset by peer]
15:05 -!- rpifan [~rpifan@207-244-191-189-dhcp.mia.fl.atlanticbb.net] has joined ##hplusroadmap
15:12 -!- entity8421[m] [entity8421@gateway/shell/matrix.org/x-hgvapkqdyitfweas] has joined ##hplusroadmap
15:23 -!- Rmesil8O4b[m] [rmesil8o4b@gateway/shell/matrix.org/x-wxzydvhorszrvtwb] has joined ##hplusroadmap
15:35 -!- Rmesil8O4b[m] [rmesil8o4b@gateway/shell/matrix.org/x-wxzydvhorszrvtwb] has quit [Read error: Connection reset by peer]
15:35 -!- entity8421[m] [entity8421@gateway/shell/matrix.org/x-hgvapkqdyitfweas] has quit [Read error: Connection reset by peer]
15:42 -!- entity8421[m] [entity8421@gateway/shell/matrix.org/x-ddoaselmjgeuymmh] has joined ##hplusroadmap
15:43 -!- entity8421[m] [entity8421@gateway/shell/matrix.org/x-ddoaselmjgeuymmh] has quit [Remote host closed the connection]
15:50 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap
15:50 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has quit [Client Quit]
15:50 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap
15:54 -!- entity8421[m] [entity8421@gateway/shell/matrix.org/x-jbavtzcjswjpqocl] has joined ##hplusroadmap
16:01 < kanzure> hyperblort
16:05 -!- Rmesil8O4b[m] [rmesil8o4b@gateway/shell/matrix.org/x-sgyyqlzcestqnfnr] has joined ##hplusroadmap
16:10 < kanzure> "I, Bill Faloon, am pleased to announce that the YOUNG BLOOD study -- conducted by the South Florida Bone Marrow/Stem Cell Transplant Institute -- to treat FRAILTY OF AGING has received FDA and INSTITUTIONAL REVIEW BOARD approval."
16:10 < kanzure> IN ALL CAPS
16:38 < fltrz> "The planar lipid bilayer method allows to build an artificial cell membrane and examine pore forming molecule functionally at the single-molecule level. The laboratory session we propose in this paper allows the students to observe directly these elementary currents produced by the activity of a single pore forming molecule, such ionic channels being the key players in the generation of the neuronal electrical activity."
16:38 < fltrz> for about 200 euros @ http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0108097#s1
16:38 -!- mindsForge [~nak@174-26-123-39.phnx.qwest.net] has joined ##hplusroadmap
16:58 -!- darsie [~username@84-114-73-160.cable.dynamic.surfer.at] has quit [Ping timeout: 260 seconds]
17:03 -!- darsie [~username@84-114-73-160.cable.dynamic.surfer.at] has joined ##hplusroadmap
17:14 < nmz787> fltrz: you can see some commentary on that between me and one of the creators here: https://groups.google.com/forum/#!topic/diybio/4CyTZSUJ6O0
17:24 -!- kwgwk [~kwgwk@boole.london.hackspace.org.uk] has quit [Ping timeout: 240 seconds]
17:35 -!- strages [uid11297@gateway/web/irccloud.com/x-oomwdexaprotfuui] has quit [Quit: Connection closed for inactivity]
17:38 -!- yashgaroth [~yashgarot@2606:6000:cd4d:3300:f5e0:f867:a11d:8d52] has joined ##hplusroadmap
17:55 < kanzure> yashgaroth: yo'sup
17:55 < yashgaroth> ayy
17:55 < kanzure> arrr
18:01 < kanzure> andrew is now funded for virus
18:01 < kanzure> wants to do recoding first
18:01 < yashgaroth> who, hessel?
18:09 < kanzure> confirm
18:09 < kanzure> "better than hitler since 2008!"
18:33 < kanzure> "An adult brain can be electron beamed scanned at a resolution of 5 cubic nanometers, producing a file size of around a yottabyte... Invest in data storage companies."
18:33 < kanzure> https://www.facebook.com/in2eternity/posts/10212994685195206
18:39 < kanzure> https://www.benthamsgaze.org/2016/10/25/how-to-do-zero-knowledge-from-discrete-logs-in-under-7kb/
19:01 -!- Douhet [~Douhet@unaffiliated/douhet] has quit [Ping timeout: 268 seconds]
19:05 -!- Douhet [~Douhet@unaffiliated/douhet] has joined ##hplusroadmap
19:11 -!- Mike_ [db7fe436@gateway/web/freenode/ip.219.127.228.54] has joined ##hplusroadmap
19:11 -!- Mike_ is now known as Guest35706
19:13 < kanzure> meme yourself a win https://www.youtube.com/watch?v=uwmeH6Rnj2E
19:17 < kanzure> .title https://www.youtube.com/watch?v=kIFm8Jtk-B0
19:17 < yoleaux> Dylan Thomas - Do not go gentle into that good night - YouTube
19:20 < kanzure> and https://www.youtube.com/watch?v=qfHzzy6T9to
19:22 -!- Guest35706 [db7fe436@gateway/web/freenode/ip.219.127.228.54] has quit [Quit: Page closed]
19:35 < kanzure> .title https://m.phys.org/news/2017-11-autonomously-synthetic-dna-strands.html
19:35 < yoleaux> kanzure: Sorry, that doesn't appear to be an HTML page.
19:36 < kanzure> "Primer Exchange Reaction (PER) cascades enable the autonomous growth of single-stranded DNAs. On the top, a 'catalytic PER hairpin' binds a first 'primer' (shown as a short grey strand), triggers its elongation with a sequence encoded by the hairpin itself, and releases it to start another cycle with the already extended primer, and so forth, until a long transcript is generated."
19:37 < kanzure> seems very similar to the catalytic proximity recording stuff from a few weeks ago
19:38 < kanzure> .tw https://twitter.com/sigfig/status/927611221435715584
19:38 < yoleaux> no amount of weird content can save a child destined to be normal (@sigfig)
19:40 < nmz787> I saw that mentioned earlier somewhere, didn't read it... pretty interesting
19:41 < nmz787> I don't quite get it yet
19:42 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has quit [Quit: brb]
19:43 < kanzure> it's similar to the proximity recording stuff..
19:43 < kanzure> "peng yin also recently published the "proximity recording" method-- using DNA molecules as a form of nanoscopic microscopy. You wait for DNA molecules to bind to their targets, then their tails overlap with each other and generate other DNA molecules that can then be sequenced to find out all the intersecting pairs on the surface of the object. So you get extremely high resolution imaging ...
19:43 < kanzure> ...data, without using optical microscopy at all."
19:45 < kanzure> (hopefully for... brain uploading, stuff.)
19:45 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has joined ##hplusroadmap
19:45 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has quit [Remote host closed the connection]
19:46 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has joined ##hplusroadmap
19:52 < nmz787> so basically, a sequence of "a" "b" "stop codon" and "b*" that will fold on itself and self-bind with a hairpin, has a sequence on one side of the hair pin "a" for primer binding, and the hairpin itself is a stop-codon. Then a primer "a*" is added and binds "a", then a strand displacing polymerase begins to elongate from "a*" into and displacing "b*", then it hits the "stop codon"
19:53 < nmz787> then you can repeat step-wise, with similar primer hairpin things... with i.e. "b" "c" "stop codon" "b*"
19:54 < nmz787> err, "b" "c" "stopcodon" "c".... then "c" "d" "stop codon" "d*"
19:54 < nmz787> c*
19:54 < nmz787> whatver
19:54 < nmz787> whatever
19:55 < nmz787> so the reaction is limited by how much/little primer you start the whole operation with
20:05 < heath> you still need a way to create the hairpin. pretty neat though. patents on this were linked a few times in here
20:05 -!- archels [charl@toad.stack.nl] has quit [Ping timeout: 255 seconds]
20:06 < heath> hairpin templates*
20:10 < kanzure> patents on hairpins?
20:13 -!- archels [charl@toad.stack.nl] has joined ##hplusroadmap
20:20 -!- aeiousomething [~aeiousome@gateway/vpn/privateinternetaccess/aeiousomething] has joined ##hplusroadmap
20:20 -!- kaleidoscope [ae3edab9@gateway/web/freenode/ip.174.62.218.185] has joined ##hplusroadmap
20:25 -!- kaleidoscope [ae3edab9@gateway/web/freenode/ip.174.62.218.185] has quit [Ping timeout: 260 seconds]
20:34 < nmz787> my grandma was using hairpins long before I was even born
20:38 -!- aeiousomething [~aeiousome@gateway/vpn/privateinternetaccess/aeiousomething] has quit [Ping timeout: 240 seconds]
20:53 < heath> patents on primer exchange reaction
20:53 < heath> on or related to
20:57 < kanzure> if you could place an engineering in charge of gp-write, who should it be?
20:57 < kanzure> trying to come up with a list of names
20:58 < kanzure> as a group they are entirely academic so it's hard to figure out the right engineering person to place there
21:16 -!- darsie [~username@84-114-73-160.cable.dynamic.surfer.at] has quit [Ping timeout: 250 seconds]
21:17 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has quit [Ping timeout: 268 seconds]
21:21 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap
21:38 -!- mindsForge [~nak@174-26-123-39.phnx.qwest.net] has quit [Remote host closed the connection]
21:43 -!- aeiousomething [~aeiousome@gateway/vpn/privateinternetaccess/aeiousomething] has joined ##hplusroadmap
22:02 -!- kanzure_ [2f1f0e01@gateway/web/freenode/ip.47.31.14.1] has joined ##hplusroadmap
22:11 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap
22:16 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 240 seconds]
22:17 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap
22:17 -!- aeiousomething [~aeiousome@gateway/vpn/privateinternetaccess/aeiousomething] has quit [Ping timeout: 248 seconds]
22:18 -!- kanzure_ [2f1f0e01@gateway/web/freenode/ip.47.31.14.1] has left ##hplusroadmap []
22:45 -!- yashgaroth [~yashgarot@2606:6000:cd4d:3300:f5e0:f867:a11d:8d52] has quit [Quit: Leaving]
22:49 -!- aeiousomething [~aeiousome@gateway/vpn/privateinternetaccess/aeiousomething] has joined ##hplusroadmap
23:17 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 250 seconds]
23:19 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has joined ##hplusroadmap
23:25 < nmz787> .title https://imgur.com/a/I3CLt
23:25 < yoleaux> culture_shock! now with ADC reporting waveform to GUI - Album on Imgur
23:26 < nmz787> I thought to go with this "glitch" effect, but the GIF was too downsized and you can't read the text on the GUI controls https://giphy.com/gifs/cultureshock-github-26u4cSa90sco4Xo0U/fullscreen
--- Log closed Tue Nov 07 00:00:08 2017