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06:31 < kanzure> .title http://www.sciencedirect.com/science/article/pii/S1534580710000067 06:33 -!- yoleaux [~yoleaux@xn--ht-1ia18f.nonceword.org] has quit [Ping timeout: 240 seconds] 06:46 < kanzure> welp 07:07 < archels> none of the protein acronyms in the title mean anything to me, I must be behind the curve 07:10 -!- aeiousomething [~aeiousome@183.82.170.54] has joined ##hplusroadmap 07:10 -!- Gurkenglas [~Gurkengla@dslb-094-223-133-187.094.223.pools.vodafone-ip.de] has quit [Ping timeout: 246 seconds] 07:16 -!- mrdata_ is now known as mrdata 07:21 -!- rustylerp [~rustylerp@2804:7f4:d568:1::cafe:9090] has quit [Remote host closed the connection] 07:28 -!- yoleaux [~yoleaux@xn--ht-1ia18f.nonceword.org] has joined ##hplusroadmap 07:30 < kanzure> .title http://www.sciencedirect.com/science/article/pii/S1534580710000067 07:30 < yoleaux> Kibra Functions as a Tumor Suppressor Protein that Regulates Hippo Signaling in Conjunction with Merlin and Expanded - ScienceDirect 07:39 -!- m4l3z [~m4l3z@2a01cb040226f200e53b8ec9266415be.ipv6.abo.wanadoo.fr] has joined ##hplusroadmap 07:40 -!- docl_ [~docl@159.203.115.16] has joined ##hplusroadmap 07:40 -!- Netsplit *.net <-> *.split quits: Hooloovo0, Qfwfq, potatope, docl, Cory 07:40 -!- Hoolootwo [~Hooloovoo@hooloovoo.blue] has joined ##hplusroadmap 07:40 -!- potatope [sid139423@gateway/web/irccloud.com/x-efvasacinvipmkua] has joined ##hplusroadmap 07:43 -!- jtimon [~quassel@41.31.134.37.dynamic.jazztel.es] has joined ##hplusroadmap 07:49 -!- Cory [~Cory@unaffiliated/cory] has joined ##hplusroadmap 07:51 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 248 seconds] 07:52 -!- WeirdTolkienishF [~Weird@unaffiliated/weirdtolkienishf] has joined ##hplusroadmap 07:52 -!- WeirdTolkienishF [~Weird@unaffiliated/weirdtolkienishf] has quit [Remote host closed the connection] 07:52 -!- WeirdTolkienishF [~Weird@unaffiliated/weirdtolkienishf] has joined ##hplusroadmap 07:53 < JayDugger> Normally I wouldn't talk about the 1990s, but Christ on a crutch! 07:53 -!- yoleaux [~yoleaux@xn--ht-1ia18f.nonceword.org] has quit [Ping timeout: 240 seconds] 07:54 -!- yoleaux [~yoleaux@xn--ht-1ia18f.nonceword.org] has joined ##hplusroadmap 07:55 < JayDugger> I do not recall this level of recycling of old ideas then. It probably happened, but I do not remember so much pouring of old wine into new bottles. Perhaps the dot-com foolishness of "e-everything!" and the like was just as bad as today's "just add blockchain for a perfect world! Now with more peace and twice the love!" 07:57 < JayDugger> Progress is relative, I get it, but damn, really? If fixing the world was so easy to do and so easy that it only needed to do once then the world would have been fixed long ago. 07:58 -!- dstrbd [~dstrbd@ec2-52-90-70-199.compute-1.amazonaws.com] has joined ##hplusroadmap 07:58 < JayDugger> And everybody seems to want to try technocracy again without looking up to see what that went nowhere. 07:59 < JayDugger> Rant's over. Thanks for bearing with it. 08:02 -!- Hoolootwo is now known as Hooloovo0 08:09 -!- Gurkenglas [~Gurkengla@dslb-094-223-133-187.094.223.pools.vodafone-ip.de] has joined ##hplusroadmap 08:23 -!- dstrbd [~dstrbd@ec2-52-90-70-199.compute-1.amazonaws.com] has quit [Remote host closed the connection] 08:23 -!- rustylerp [~rustylerp@2804:7f4:d568:1::cafe:9090] has joined ##hplusroadmap 08:24 -!- dstrbd [~dstrbd@ec2-52-90-70-199.compute-1.amazonaws.com] has joined ##hplusroadmap 08:27 -!- dstrbd [~dstrbd@ec2-52-90-70-199.compute-1.amazonaws.com] has quit [Client Quit] 08:45 -!- Qfwfq [Qfwfq@gateway/shell/suchznc/x-utqhxdijaxsacntd] has joined ##hplusroadmap 08:45 -!- Qfwfq [Qfwfq@gateway/shell/suchznc/x-utqhxdijaxsacntd] has quit [Changing host] 08:45 -!- Qfwfq [Qfwfq@unaffiliated/washirving] has joined ##hplusroadmap 08:45 -!- Qfwfq [Qfwfq@unaffiliated/washirving] has quit [Changing host] 08:45 -!- Qfwfq [Qfwfq@gateway/shell/suchznc/x-utqhxdijaxsacntd] has joined ##hplusroadmap 08:50 -!- augur [~augur@2600:380:8533:d5d5:4def:722b:b973:438a] has joined ##hplusroadmap 08:51 -!- ebowden [~ebowden@2001:8003:103f:8600:5cb0:82e0:7d55:c6bc] has quit [Read error: Connection reset by peer] 08:52 -!- ebowden [~ebowden@2001:8003:103f:8600:edaf:a865:535f:2cd] has joined ##hplusroadmap 09:00 -!- rustyler_ [~rustylerp@2804:7f4:d568:1::cafe:9090] has joined ##hplusroadmap 09:00 -!- rustylerp [~rustylerp@2804:7f4:d568:1::cafe:9090] has quit [Read error: Connection reset by peer] 09:46 -!- NikopolSohru [~NSohru@89.38.98.78] has joined ##hplusroadmap 09:47 -!- CheckDavid [uid14990@gateway/web/irccloud.com/x-kddufgfhxuuqfclu] has joined ##hplusroadmap 09:49 -!- rustyler_ [~rustylerp@2804:7f4:d568:1::cafe:9090] has quit [] 09:50 -!- rustylerp [~rustylerp@2804:7f4:d568:1::cafe:9090] has joined ##hplusroadmap 09:51 -!- rustylerp [~rustylerp@2804:7f4:d568:1::cafe:9090] has quit [Client Quit] 09:51 < kanzure> a debugging tool thing for people to check their bitcoin transactions and degrade their privacy https://transactionfee.info/ 09:51 < kanzure> should be client-side script to analyze serialized transaction 09:51 -!- rustylerp [~rustylerp@2804:7f4:d568:1::cafe:9090] has joined ##hplusroadmap 09:59 -!- Storyteller [~Storytell@unaffiliated/storyteller] has joined ##hplusroadmap 10:00 -!- Storyteller [~Storytell@unaffiliated/storyteller] has left ##hplusroadmap [] 11:30 -!- DataPacRat [~dan@adsl-130.itcanada.com] has joined ##hplusroadmap 11:38 -!- dstrbd [~dstrbd@ec2-52-90-70-199.compute-1.amazonaws.com] has joined ##hplusroadmap 12:02 -!- dstrbd [~dstrbd@ec2-52-90-70-199.compute-1.amazonaws.com] has quit [Quit: dstrbd] 12:08 -!- augur [~augur@2600:380:8533:d5d5:4def:722b:b973:438a] has quit [Ping timeout: 265 seconds] 12:12 -!- aeiousomething [~aeiousome@183.82.170.54] has quit [Ping timeout: 240 seconds] 12:16 -!- dstrbd [~dstrbd@ec2-52-90-70-199.compute-1.amazonaws.com] has joined ##hplusroadmap 12:18 < maaku> question to the bio-knowledgeable here : anyone have any suggestions for lowering resting heart rate? 12:19 < maaku> like, I naively assume that maybe increasing capillary blood volume (via targeted supllements and exercise) would reduce tachycardia? 12:19 < maaku> but I'm a newb here (I work with machines, not meat) and looking for ideas from people more knowledgeable 12:20 < maaku> (yes I'm talking to my doctor, but I'm also looking for outside the box ideas) 12:21 < kanzure> stimultants raise resting heart rate 12:21 < maaku> yeah but even off stimulants my resting rate is 90-100 12:23 < maaku> it's on my todo list to find a new general practitioner and have this looked at by a fresh set of eyes 12:23 < JayDugger> There's a lot of snake oil out there, but HRV biofeedback might help. 12:23 < JayDugger> https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104929/ 12:23 < JayDugger> Doesn't talk much about resting pulse rate, but it might do for a start. 12:23 < maaku> with no indication of anything else wrong the medical advice is "let's wait and see..." which frustrates me as a proactive person 12:24 < maaku> thanks JayDugger 12:24 < JayDugger> You're welcome. Whether it helps, I hope you find something effective. Please mention it here if you do. 12:24 < maaku> will do 12:25 < JayDugger> And just to sound like every doctor ever, "exercise." 12:25 < maaku> I added it to my reading list and will review later 12:25 < maaku> yeah I'm doing that. i'm getting in shape, losing weight, and building strength too, which is great 12:26 < maaku> but so far heart rate is pretty much the same as when I started collecting data (Sept '17) 12:27 < maaku> the medical response seems to be "meh" since there's no indications of anything else wrong, but I'm pretty worried as resting heart rate correlates VERY well inversely with lifespan 12:27 < JayDugger> Oh? Have you a good heart rate monitor? 12:27 < maaku> I'm not sure it's "good", but I have an Apple Watch 3 12:28 < JayDugger> Yeah, I know. I have a similar worry about that correlation. I could give up coffee, but somehow... 12:28 < maaku> JayDugger: fwiw I've found caffeine, even in small amounts, to have 3-4x as much of an increase to my heart rate as amphetamines 12:29 < maaku> 50mg Vyvanse raises my heart rate 5-10bpm. A cup of coffee puts it through the roof. 12:29 < maaku> That might be me though. I've always had a strange reaction to caffeine and tried to avoid it. 12:30 < maaku> (Vyvanse + coffee results in "lay down and practice medidation for 5 hours until my chest stops pounding") 12:30 < JayDugger> Huh. That's really strange. My wife makes similar complaints about vyvanse and coffee too. 12:32 -!- m4l3z [~m4l3z@2a01cb040226f200e53b8ec9266415be.ipv6.abo.wanadoo.fr] has quit [Quit: Leaving] 12:32 < JayDugger> She takes much smaller does of Vyvanse (now with correct spelling!) than that: perhaps 10 mg tops? 12:32 -!- rustylerp [~rustylerp@2804:7f4:d568:1::cafe:9090] has quit [Remote host closed the connection] 12:32 < maaku> Yikes that's as small as they get. 12:32 < JayDugger> And a half cup of coffee will last her two days, longer if I don't throw it out. 12:33 < maaku> Vyvanse is super-XR, so that's very little amphetamine in the systme 12:33 < maaku> I just stopped drinking entirely. Don't need it anyway with Vyvanse. (If she does feel she needs coffee, maybe her dose is too low?) 12:33 < JayDugger> Yeah, I think most days she does it for the sake of the ritual of taking the pill. I can sometimes tell a small difference in her behavior. 12:34 < JayDugger> Again, I think it is the ritual of morning coffee. 12:34 < maaku> Ah. I find soylent a healther alternative ritual. 12:34 < maaku> Then refill the bottle with water to stay hydrated. 12:34 < JayDugger> Yeah, she hates the smell. And spirulina's aroma makes her retch. 12:34 < maaku> Fair enough. I do miss the smell of coffee in the morning. 12:35 < JayDugger> Anyhow, did less coffee drop, ah from that comment I suspect you've cut back on coffee. 12:35 < JayDugger> Can you tell if that helps, and how much? 12:35 -!- Jenda` [~jenda@coralmyn.hrach.eu] has quit [Ping timeout: 268 seconds] 12:35 < maaku> I don't know. I never had a daily coffee habit, and I cut it entirely before I started tracking heart rate. 12:36 < maaku> But now, if I have coffee it adds 10-20bpm bringing me up to 130bpm *resting* (lying down!) heart rate. 12:36 < maaku> Coffee or tea 12:37 -!- Jenda` [~jenda@coralmyn.hrach.eu] has joined ##hplusroadmap 12:37 < maaku> Coffee always made me jittery. I used to think that was just neural effects, but in retrospect it was probably a body physiological response to tachycardia 12:38 < maaku> Theonine (tea) or sugar (consensed milk) soothes the jitters, but doesn't decrease the heart rate. 12:45 < JayDugger> Tried theanine supplements? 12:47 -!- bsm117532 [~mcelrath@173-9-124-61-NewEngland.hfc.comcastbusiness.net] has quit [Ping timeout: 276 seconds] 12:48 < maaku> Yeah makes coffee like tea -- no jitters but still heart rate increase 12:48 < maaku> Oh you mean daily, even without caffeine? No I haven't. That's a decent idea 12:48 -!- Proteus_ [~proteus@unaffiliated/proteus] has quit [Remote host closed the connection] 12:50 < maaku> I'll try that 12:51 < JayDugger> The latter, yes. I used to combine theanine with coffee when I worked nights and had a long commute. 12:51 < JayDugger> Coffee to wake up and drive, theanine to calm down for work. 12:52 < JayDugger> It worked, but I didn't like the idea of having to time onset and duration. 12:53 -!- Jenda` [~jenda@coralmyn.hrach.eu] has quit [Ping timeout: 268 seconds] 12:53 -!- Jenda` [~jenda@coralmyn.hrach.eu] has joined ##hplusroadmap 12:57 -!- rustylerp [~rustylerp@189.112.238.249] has joined ##hplusroadmap 13:02 -!- rustylerp [~rustylerp@189.112.238.249] has quit [Ping timeout: 268 seconds] 13:05 -!- Jenda` [~jenda@coralmyn.hrach.eu] has quit [Ping timeout: 268 seconds] 13:06 -!- Jenda` [~jenda@coralmyn.hrach.eu] has joined ##hplusroadmap 13:07 -!- rustylerp [~rustylerp@189.112.238.249] has joined ##hplusroadmap 13:13 -!- NikopolSohru [~NSohru@89.38.98.78] has quit [Ping timeout: 256 seconds] 13:31 -!- brujo_biologica [~brujo@li1745-37.members.linode.com] has quit [Quit: leaving] 13:36 -!- augur [~augur@2600:380:8510:701f:b552:8b29:c1e9:a98c] has joined ##hplusroadmap 13:45 -!- ebowden_ [~ebowden@2001:8003:103f:8600:b189:5034:b5c4:f058] has joined ##hplusroadmap 13:47 -!- ebowden_ [~ebowden@2001:8003:103f:8600:b189:5034:b5c4:f058] has quit [Read error: Connection reset by peer] 13:48 -!- ebowden [~ebowden@2001:8003:103f:8600:edaf:a865:535f:2cd] has quit [Ping timeout: 265 seconds] 13:59 -!- kelu124 [b09efc21@gateway/web/freenode/ip.176.158.252.33] has joined ##hplusroadmap 13:59 < kelu124> hey there 14:01 < kelu124> There some thoughts here a couple of month back about time-reversal for single-element ultrasound imaging, and pooof - it's been done "Compressive 3D ultrasound imaging using a single sensor" (cf http://advances.sciencemag.org/content/3/12/e1701423 ) . Very interesting read. 14:01 < kelu124> Really looking forward to having it matched with another tech "Researchers discover new use for ultrasound technology to help amputees" ( https://techxplore.com/news/2017-11-ultrasound-technology-amputees.html ) 14:02 < kelu124> Bim - free extra limbs ! 14:02 < kanzure> howdy. thanks. 14:02 < kelu124> hey kanzure 14:03 < kelu124> i know you had some interest on the topic in the past 14:03 -!- NikopolSohru [~NSohru@s5596eed8.adsl.online.nl] has joined ##hplusroadmap 14:03 < kanzure> yeah still do..... ultrasound project going slowly on my end, someone moved from china to US which was a big interruption. 14:04 -!- Nikopol_ [~NSohru@89.38.98.78] has joined ##hplusroadmap 14:04 < kelu124> arf 14:05 < kelu124> you may find this interesting: it's been active recently - https://github.com/ColumbiaOpenSourceUltrasound 14:05 < kelu124> they're giving some thoughts to all pieces 14:06 < kanzure> long-term i want to eventually move on to phased array power/energy delivery (for tumor ablation or at lower power for neural stimulation) 14:07 < kelu124> been through the logs - seen you identified butterfly network recent product. The CMUTs may yield something 14:07 -!- razzy [~user@unaffiliated/razzy] has joined ##hplusroadmap 14:08 -!- NikopolSohru [~NSohru@s5596eed8.adsl.online.nl] has quit [Ping timeout: 240 seconds] 14:08 < kanzure> i've been wondering about running a piezo inkjet head at really high frequency (some of them get up to 1 MHz per element) but no time to experiment (also have a potential use case for custom manufacturing printheads for something else) 14:09 -!- aeiousomething [~aeiousome@183.82.170.54] has joined ##hplusroadmap 14:10 < kelu124> interesting 14:11 < kelu124> btw, just thinking of this - but with a single element with a chaotic lens in front of it, and the right excitation sequence, you may be able to deliver a (small) pack where the beam focuses again 14:11 -!- augur [~augur@2600:380:8510:701f:b552:8b29:c1e9:a98c] has quit [Ping timeout: 246 seconds] 14:15 -!- DataPacRat [~dan@adsl-130.itcanada.com] has quit [Ping timeout: 248 seconds] 14:17 -!- WeirdTolkienishF [~Weird@unaffiliated/weirdtolkienishf] has quit [Quit: Leaving] 14:17 -!- ebowden [~ebowden@2001:8003:103f:8600:b189:5034:b5c4:f058] has joined ##hplusroadmap 14:20 < kanzure> kelu124: pack? 14:21 < kanzure> kelu124: for brain stimulation stuff, things like https://www.biorxiv.org/content/early/2018/01/01/241406 (more recent) but otherwise http://diyhpl.us/~bryan/papers2/neuro/ultrasound/ 14:21 < kelu124> i meant it could deliver a small punch / pack of energy 14:22 < kelu124> must say I'm mostly in favor of giving small punches to my forearm muscles than in my brain. maybe not brave/curious enough. 14:22 < kelu124> maybe numbing nerves though.. 14:23 -!- ebowden [~ebowden@2001:8003:103f:8600:b189:5034:b5c4:f058] has quit [Ping timeout: 265 seconds] 14:23 < kanzure> kelu124: nobody should ever test on their own brain for a prototype, of course. 14:23 < kanzure> but lots of other testing opportunities 14:24 < kelu124> temperature-sensitive jellies yummy ! 14:24 < kanzure> oh you mean chaotic lense + single emitter? 14:25 < kanzure> yes you said single, interesting thought 14:26 < kelu124> yup 14:26 < kelu124> knowing your chaotic lense, with a nice adc/dac, would enable you to encode the place of focalisation through time reversal 14:28 < kelu124> i personnaly plan to do some tests on the above-mentioned topic (ultrasound prosthetics designs on a single-element design) for which I'm working on a ice40 board -- but would most definitely would love to experiment on focusing some signal back 14:28 < kelu124> it would need a pretty nice dac though 14:30 -!- spurserh [68840151@gateway/web/freenode/ip.104.132.1.81] has joined ##hplusroadmap 14:31 < spurserh> heyo 14:31 < kanzure> spurserh: kelu124 proposes using a single emitter element + chaotic lense and encode focalization with a signal, for targeted energy delivery 14:31 < spurserh> I'll have to do some research to understand what that means 14:31 < kelu124> hey 14:32 < kelu124> keyword there would be time-reversal 14:32 < kelu124> but then time-reversal has been quite well studied so far 14:32 < kanzure> spurserh: well it's instead of using multiple emitter elements. but also, adding more elements probably isn't that big of a deal..... is it? 14:33 < spurserh> we are talking about imaging, or heating tissue? you said "energy delivery" 14:33 < kanzure> heating 14:34 < kanzure> sonoporation etc 14:34 < kanzure> but also, multi-element is nice for imaging 14:35 < spurserh> I've only really thought about imaging, tho that's interesting stuff to be sure 14:35 < spurserh> but since I'm at work, I don't think I can take the time to read up on it at this moment 14:35 < kelu124> actualy, a chaotic interface multiplies a single source into a number of emitters that are well above what an array/matrix would have 14:36 < kelu124> once you know the signature of your chaos, you can encode beamforming into the time-encoded excitation of your piezo 14:36 < kanzure> other thing i was wondering about (and i recognize this might be garbage) but can imaging be improved by using a patterned surface on the other side of the human body? e.g. metamaterials, grooved surfaces, etc. 14:37 < kanzure> also, why is imaging done with a single emitter instead of a sender/receiver positioned on opposite sides of the object? 14:38 < kelu124> hum never tried - but i would assume that another piezo to retrieve the signal on the other side would definitely bring info. Unsure about energy uses however as there would be many many scatterers along the way 14:38 < kanzure> one more piece of garbage, but it would be really convenient if piezo inkjets could be used for imaging :-/ 14:38 < kelu124> there has been some imaging done this way - the way a scanner would work. However, it's much easier for a doctor to use (normally) a handheld probe with a single interface to master. especially for superficial imaging 14:39 -!- ebowden [~ebowden@2001:8003:103f:8600:b189:5034:b5c4:f058] has joined ##hplusroadmap 14:39 < maaku> kanzure: here's a cheapo superpower: augmented reality vive (video feed -> head set display) with these filters : http://people.csail.mit.edu/mrub/vidmag/ 14:40 < maaku> would allow you to see small motions, tiny changes in color 14:40 < maaku> i wonder how well the motion sensitivity would work on a mobile camera though 14:40 -!- yoleaux [~yoleaux@xn--ht-1ia18f.nonceword.org] has quit [Ping timeout: 240 seconds] 14:41 -!- yoleaux [~yoleaux@xn--ht-1ia18f.nonceword.org] has joined ##hplusroadmap 14:41 < maaku> direct link to video : https://www.youtube.com/watch?v=e9ASH8IBJ2U 14:41 < kanzure> maaku: how about lidar :-/ 14:42 < kelu124> this one seems fun too : https://www.youtube.com/watch?v=EhZXDgG9oSk 14:42 -!- drewbot [~cinch@54.82.113.167] has quit [Remote host closed the connection] 14:42 < kanzure> .title 14:42 < yoleaux> Detecting Pulse From Head Motions in Video - YouTube 14:42 < spurserh> @kelu124 where did you find this? do you know any background on it, sample images? https://github.com/ColumbiaOpenSourceUltrasound 14:43 < kelu124> @spurserh nope just discovered it recently while doing the usual stroll in the DIY ultrasound park 14:44 -!- ebowden [~ebowden@2001:8003:103f:8600:b189:5034:b5c4:f058] has quit [Ping timeout: 246 seconds] 14:46 -!- drewbot [~cinch@54.211.141.76] has joined ##hplusroadmap 14:46 -!- yoleaux [~yoleaux@xn--ht-1ia18f.nonceword.org] has quit [Ping timeout: 240 seconds] 14:47 < kelu124> got to go, see you around soon 14:47 < kanzure> seeya 14:50 -!- augur [~augur@2600:380:8577:7a56:d08e:b5b:f30c:4789] has joined ##hplusroadmap 14:51 -!- kelu124 [b09efc21@gateway/web/freenode/ip.176.158.252.33] has quit [Ping timeout: 260 seconds] 14:53 -!- ebowden 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[~ebowden@2001:8003:103f:8600:b189:5034:b5c4:f058] has quit [Ping timeout: 255 seconds] 15:46 < kanzure> are the details of the raelian coning lawsuit public? 15:47 < nmz787> what? 15:48 < nmz787> they're getting sued? 15:48 < nmz787> elohim will be unhappy 15:48 < kanzure> no this was 1996 15:52 -!- v0id3301 [~quassel@ec2-18-219-8-108.us-east-2.compute.amazonaws.com] has joined ##hplusroadmap 15:55 < nmz787> huh, their RMX2010 seems like essentially an electroporator 15:55 < nmz787> low-voltage 15:55 -!- ebowden [~ebowden@2001:8003:103f:8600:b189:5034:b5c4:f058] has joined ##hplusroadmap 15:55 < nmz787> lower (well depends on the electrode distance) 15:59 < kanzure> https://www.clonaid.com/page.php?9 15:59 -!- ebowden [~ebowden@2001:8003:103f:8600:b189:5034:b5c4:f058] has quit [Ping timeout: 256 seconds] 16:02 < kanzure> "Clonaid's sister company, Stemaid, has launched an anti-aging program using stem cells derived from clone embryos." 16:08 -!- mrdata- [~mrdata@unaffiliated/mrdata] has joined ##hplusroadmap 16:11 -!- ebowden [~ebowden@2001:8003:103f:8600:b189:5034:b5c4:f058] has joined ##hplusroadmap 16:12 -!- strages [uid11297@gateway/web/irccloud.com/x-dnlqmtfienfdipmb] has quit [Ping timeout: 256 seconds] 16:14 -!- DataPacRat [~dan@adsl-130.itcanada.com] has quit [Ping timeout: 248 seconds] 16:16 -!- ebowden [~ebowden@2001:8003:103f:8600:b189:5034:b5c4:f058] has quit [Ping timeout: 255 seconds] 16:28 -!- ebowden [~ebowden@2001:8003:103f:8600:b189:5034:b5c4:f058] has joined ##hplusroadmap 16:33 -!- ebowden [~ebowden@2001:8003:103f:8600:b189:5034:b5c4:f058] has quit [Ping timeout: 246 seconds] 16:38 -!- darsie [~username@84-114-73-160.cable.dynamic.surfer.at] has quit [Ping timeout: 240 seconds] 16:43 -!- ebowden [~ebowden@2001:8003:103f:8600:b189:5034:b5c4:f058] has joined ##hplusroadmap 16:45 -!- rustylerp [~rustylerp@189.112.238.249] has quit [Remote host closed the connection] 16:46 -!- yoleaux [~yoleaux@xn--ht-1ia18f.nonceword.org] has joined ##hplusroadmap 16:49 -!- ebowden [~ebowden@2001:8003:103f:8600:b189:5034:b5c4:f058] has quit [Ping timeout: 265 seconds] 16:50 -!- aeiousomething [~aeiousome@183.82.170.54] has quit [Read error: Connection reset by peer] 16:50 -!- aeiousomething [~aeiousome@183.82.170.54] has joined ##hplusroadmap 16:51 -!- dstrbd [~dstrbd@ec2-52-90-70-199.compute-1.amazonaws.com] has quit [Quit: dstrbd] 17:06 -!- ebowden [~ebowden@2001:8003:103f:8600:b189:5034:b5c4:f058] has joined ##hplusroadmap 17:08 -!- rpifan [~rpifan@172.56.26.241] has joined ##hplusroadmap 17:09 -!- rpifan [~rpifan@172.56.26.241] has left ##hplusroadmap [] 17:11 -!- ebowden [~ebowden@2001:8003:103f:8600:b189:5034:b5c4:f058] has quit [Ping timeout: 265 seconds] 17:28 < kanzure> https://ipfs.io/ipfs/QmZwkh5DcC3MZ4q9SX1QtcNG7HwKNrnACBaX1hfxfsJUU8/podcast-transcription-amazon-transcribe/ 17:31 -!- ebowden [~ebowden@2001:8003:103f:8600:b189:5034:b5c4:f058] has joined ##hplusroadmap 17:35 -!- ebowden 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aeiousomething [~aeiousome@183.82.170.54] has quit [Ping timeout: 240 seconds] 18:47 -!- ebowden [~ebowden@2001:8003:103f:8600:b189:5034:b5c4:f058] has quit [Ping timeout: 246 seconds] 18:50 -!- augur [~augur@2600:380:864e:cff3:a87a:3a38:e592:4f90] has joined ##hplusroadmap 18:56 -!- ebowden [~ebowden@2001:8003:103f:8600:b189:5034:b5c4:f058] has joined ##hplusroadmap 19:01 -!- ebowden [~ebowden@2001:8003:103f:8600:b189:5034:b5c4:f058] has quit [Ping timeout: 255 seconds] 19:02 < kanzure> .wik plasma window 19:02 < yoleaux> "The plasma window (not to be confused with a plasma shield) is a technology that fills a volume of space with plasma confined by a magnetic field. With current technology, this volume is quite small and the plasma is generated as a flat plane inside a cylindrical space." — https://en.wikipedia.org/wiki/Plasma_window 19:05 < kanzure> too much vortex https://www.youtube.com/watch?v=1C_40B9m4tI 19:09 < kanzure> well anyway, inkjet printhead manufacturing is probably same thing required for high-density ultrasound imaging transducer arrays....... i can't imagine the process being much different. 19:09 -!- yoleaux [~yoleaux@xn--ht-1ia18f.nonceword.org] has quit [Ping timeout: 240 seconds] 19:09 -!- yoleaux [~yoleaux@xn--ht-1ia18f.nonceword.org] has joined ##hplusroadmap 19:19 -!- ebowden [~ebowden@2001:8003:103f:8600:b189:5034:b5c4:f058] has joined ##hplusroadmap 19:24 -!- Gurkenglas [~Gurkengla@dslb-094-223-133-187.094.223.pools.vodafone-ip.de] has quit [Ping timeout: 256 seconds] 19:25 -!- ebowden [~ebowden@2001:8003:103f:8600:b189:5034:b5c4:f058] has quit [Ping timeout: 276 seconds] 19:25 -!- drewbot [~cinch@54.162.220.167] has joined ##hplusroadmap 19:35 -!- augur [~augur@2600:380:864e:cff3:a87a:3a38:e592:4f90] has quit [Ping timeout: 265 seconds] 19:44 -!- ebowden [~ebowden@2001:8003:103f:8600:b189:5034:b5c4:f058] has joined ##hplusroadmap 19:49 -!- ebowden [~ebowden@2001:8003:103f:8600:b189:5034:b5c4:f058] has quit [Ping timeout: 246 seconds] 19:51 -!- rustylerp [~rustylerp@189.112.238.249] has joined ##hplusroadmap 19:54 -!- ebowden [~ebowden@2001:8003:103f:8600:b189:5034:b5c4:f058] has joined ##hplusroadmap 19:56 -!- rustylerp [~rustylerp@189.112.238.249] has quit [Ping timeout: 264 seconds] 19:59 -!- ebowden [~ebowden@2001:8003:103f:8600:b189:5034:b5c4:f058] has quit [Ping timeout: 255 seconds] 20:09 -!- rustylerp [~rustylerp@189.112.238.249] has joined ##hplusroadmap 20:12 -!- ebowden [~ebowden@2001:8003:103f:8600:b189:5034:b5c4:f058] has joined ##hplusroadmap 20:14 -!- rustylerp [~rustylerp@189.112.238.249] has quit [Ping timeout: 240 seconds] 20:17 -!- ebowden [~ebowden@2001:8003:103f:8600:b189:5034:b5c4:f058] has quit [Ping timeout: 246 seconds] 20:23 < fenn> inkjet head and ultrasound transducer are different materials 20:23 < fenn> at least the nozzle part is different 20:24 < kanzure> captain suggests grinding down/away the nozzles 20:25 < fenn> yeah fuck nozzles, who needs 'em 20:26 < fenn> anyway i thought nozzles were silicon 20:27 < kanzure> is inkje printhead manufacturing == mems? it's larger scale isn't it? 20:27 < fenn> it's about the same scale 20:28 < fenn> "Konica Minolta's inkjet printheads are around 500 µm thick, and the nozzle aperture diameter is only around 10 µm" 20:28 -!- rustylerp [~rustylerp@189.112.238.249] has joined ##hplusroadmap 20:28 < fenn> "MEMS are made up of components between 1 and 100 micrometres in size" 20:28 -!- ebowden [~ebowden@2001:8003:103f:8600:b189:5034:b5c4:f058] has joined ##hplusroadmap 20:28 < fenn> MEMS is kinda vague 20:32 -!- rustylerp [~rustylerp@189.112.238.249] has quit [Ping timeout: 240 seconds] 20:33 -!- ebowden [~ebowden@2001:8003:103f:8600:b189:5034:b5c4:f058] has quit [Ping timeout: 265 seconds] 20:37 < kanzure> might be submicron for control circuitry in inkjet printheads? 20:39 -!- DataPacRat [~dan@adsl-149.itcanada.com] has joined ##hplusroadmap 20:39 -!- brujo_biologica [~brujo@li1745-37.members.linode.com] has quit [Quit: leaving] 20:40 < fenn> i doubt it, they're big honkin resistors for bubblejet 20:41 < fenn> i can't think of any other electronics that would be in the nozzle part 20:42 -!- aeiousomething [~aeiousome@183.82.170.54] has joined ##hplusroadmap 20:42 < kanzure> inkjets seem like one of the only tools we have available for on-demand multiplexing, other than micromirror arrays and liquid crystal displays 20:43 < kanzure> and they seem to be easier to scale up than micromirrors 20:43 < kanzure> i guess you could probably buy lots of cheap liquid crystal displays if someone has a high error rate in their manufacturing process.... but i think everyone optimizes that out. 20:46 -!- rustylerp [~rustylerp@189.112.238.249] has joined ##hplusroadmap 20:47 -!- ebowden [~ebowden@2001:8003:103f:8600:b189:5034:b5c4:f058] has joined ##hplusroadmap 20:50 -!- rustylerp [~rustylerp@189.112.238.249] has quit [Ping timeout: 240 seconds] 20:52 -!- brujo_biologica [~brujo@li1745-37.members.linode.com] has joined ##hplusroadmap 20:52 < kanzure> a little birdie says that the big billionaires strongly prefer immortality over brain uploading or vitrification interventions 20:52 -!- ebowden [~ebowden@2001:8003:103f:8600:b189:5034:b5c4:f058] has quit [Ping timeout: 265 seconds] 20:52 < kanzure> too bad. i thought they would understand the concept of hedging the bets there. hrm. 20:54 < brujo_biologica> of course because they want perpetual life not perpetual existance 20:55 < kanzure> huh? 21:00 -!- ebowden [~ebowden@2001:8003:103f:8600:b189:5034:b5c4:f058] has joined ##hplusroadmap 21:04 -!- rustylerp [~rustylerp@189.112.238.249] has joined ##hplusroadmap 21:05 -!- emeraldgreen [~user@188.227.115.178] has joined ##hplusroadmap 21:05 -!- ebowden [~ebowden@2001:8003:103f:8600:b189:5034:b5c4:f058] has quit [Ping timeout: 255 seconds] 21:06 -!- ebowden [~ebowden@2001:8003:103f:8600:b189:5034:b5c4:f058] has joined ##hplusroadmap 21:08 -!- rustylerp [~rustylerp@189.112.238.249] has quit [Ping timeout: 240 seconds] 21:10 -!- Burninate [~Burn@pool-96-241-130-178.washdc.fios.verizon.net] has quit [Read error: Connection reset by peer] 21:11 -!- Burninate [~Burn@pool-96-241-130-178.washdc.fios.verizon.net] has joined ##hplusroadmap 21:11 -!- ebowden [~ebowden@2001:8003:103f:8600:b189:5034:b5c4:f058] has quit [Ping timeout: 255 seconds] 21:12 < brujo_biologica> in regards to immortality. They want to keep their body/self-image, and not just "exist" 21:12 -!- brujo_biologica [~brujo@li1745-37.members.linode.com] has quit [Quit: leaving] 21:13 -!- brujo_biologica [~brujo@li1745-37.members.linode.com] has joined ##hplusroadmap 21:21 < kanzure> for anti-aging studies or interventions, my current thinking is that we've probably only ever done less than 100k autopsies in an academic/scientific setting 21:21 < kanzure> so we should just get a million ancient dead people and do full thorough analysis of everything 21:21 < kanzure> for starters. 21:21 < kanzure> just a massive quantity of dead people 21:22 -!- rustylerp [~rustylerp@189.112.238.249] has joined ##hplusroadmap 21:22 -!- v0id3301 is now known as void_3301 21:23 -!- TC [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has joined ##hplusroadmap 21:23 < kanzure> using near-death old people, i think you could use their circulatory system as a bioreactor for the directed evolution of young blood rejuvenation therapies, using inline mutagenesis on the additional blood 21:24 < kanzure> immuno-compatible organ xenotransplantation should be on the near-term horizon probably 5-10 years if money continues to be thrown at the problem 21:26 < kanzure> target doesn't have to be rejuvenation of course, just minimal aging as indicated by deltas between tissue biopsy assays (not sure we have an aging assay that is sensitive enough to ~6 months samples) 21:26 -!- rustylerp [~rustylerp@189.112.238.249] has quit [Ping timeout: 248 seconds] 21:27 -!- hehelleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has quit [Ping timeout: 256 seconds] 21:28 -!- justan0theruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 21:28 -!- justan0theruser [~justanoth@unaffiliated/justanotheruser] has quit [Client Quit] 21:28 -!- justan0theruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 21:29 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has quit [Ping timeout: 248 seconds] 21:36 -!- ebowden [~ebowden@2001:8003:103f:8600:b189:5034:b5c4:f058] has joined ##hplusroadmap 21:40 -!- rustylerp [~rustylerp@189.112.238.249] has joined ##hplusroadmap 21:41 -!- ebowden [~ebowden@2001:8003:103f:8600:b189:5034:b5c4:f058] has quit [Ping timeout: 265 seconds] 21:44 -!- DataPacRat [~dan@adsl-149.itcanada.com] has quit [Ping timeout: 248 seconds] 21:45 -!- rustylerp [~rustylerp@189.112.238.249] has quit [Ping timeout: 260 seconds] 21:55 -!- ebowden [~ebowden@2001:8003:103f:8600:b189:5034:b5c4:f058] has joined ##hplusroadmap 21:58 -!- rustylerp [~rustylerp@189.112.238.249] has joined ##hplusroadmap 21:59 -!- DataPacRat [~dan@adsl-127.itcanada.com] has joined ##hplusroadmap 22:00 -!- ebowden [~ebowden@2001:8003:103f:8600:b189:5034:b5c4:f058] has quit [Ping timeout: 246 seconds] 22:03 -!- rustylerp [~rustylerp@189.112.238.249] has quit [Ping timeout: 260 seconds] 22:11 -!- ebowden [~ebowden@2001:8003:103f:8600:b189:5034:b5c4:f058] has joined ##hplusroadmap 22:15 -!- ebowden [~ebowden@2001:8003:103f:8600:b189:5034:b5c4:f058] has quit [Ping timeout: 265 seconds] 22:16 -!- rustylerp [~rustylerp@189.112.238.249] has joined ##hplusroadmap 22:20 -!- ebowden [~ebowden@2001:8003:103f:8600:b189:5034:b5c4:f058] has joined ##hplusroadmap 22:21 -!- rustylerp [~rustylerp@189.112.238.249] has quit [Ping timeout: 260 seconds] 22:25 -!- ebowden [~ebowden@2001:8003:103f:8600:b189:5034:b5c4:f058] has quit [Ping timeout: 246 seconds] 22:36 -!- rustylerp [~rustylerp@189.112.238.249] has joined ##hplusroadmap 22:42 -!- rustylerp [~rustylerp@189.112.238.249] has quit [Ping timeout: 276 seconds] 22:46 -!- void_3301 [~quassel@ec2-18-219-8-108.us-east-2.compute.amazonaws.com] has quit [Quit: http://quassel-irc.org - Chat comfortably. 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