--- Log opened Sat Feb 03 00:00:16 2018
--- Day changed Sat Feb 03 2018
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05:55 < JayDugger> Good morning, everyone.
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07:18 < kanzure> scihouse should do muscular dystrophy fix things.
07:19 < gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=de3257e8 Bryan Bishop: add code link >> http://diyhpl.us/diyhpluswiki/transcripts/blockchain-protocol-analysis-security-engineering/2018/bulletproofs/
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15:10 < kanzure> what do y'all think about scihouse
15:10 < kanzure> nuke it or keep it?
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16:14 < kanzure> is there a hunger insensitivity mutation?
16:14 < kanzure> hunger is probably really robust as a signal.. no way a single mutation is going to kill that.
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16:58 < kanzure> .tw https://twitter.com/Addgene/status/959942076531167237
16:58 < yoleaux> Plasmids 101: Fluorescent Protein Timers - Use #FluorescentProtein timers to monitor the timing of cellular events #cellBio https://hubs.ly/H09PCsS0 by @TyFordFever (@Addgene)
17:04 < kanzure> .tw https://twitter.com/DARPA/status/959827469787451392
17:04 < yoleaux> BTO Director Justin Sanchez speaking at #bdyhax2018 this morning to reach early adopters of biotech & spark discussions about whether & how such tech should be applied in future. Neurotechnology & pandemic prevention on the docket. http://www.darpa.mil/program/our-research/darpa-and-the-brain-initiative http://www.darpa.mil/news-events/2017-02-06a https://pbs.twimg.com/media/DVH9eYQW0AEd13g.jpg https://pbs.twimg.com/media/
17:04 < yoleaux> DVH97fpXcAENBYI.jpg (@DARPA)
17:06 < kanzure> .tw https://twitter.com/kicad_pcb/status/959783215774027776
17:06 < yoleaux> At #FOSDEM, Wayne announced the single largest donation to the @kicad_pcb project to date. https://pbs.twimg.com/media/DVHVpEwWkAArBsS.jpg (@kicad_pcb)
17:15 < kanzure> .tw https://twitter.com/OpenAI/status/958746302451408896
17:15 < yoleaux> Announcing Requests for Research 2.0, a new set of unsolved problems which have come up in the course of our research at OpenAI: https://blog.openai.com/requests-for-research-2/. Intended for newcomers and practitioners alike! (@OpenAI)
17:24 < kanzure> .tw https://twitter.com/kristenvbrown/status/959902542237982725
17:24 < yoleaux> Hey look, it’s Gizmodo’s @dvorsky talking DIY gene therapy with Meow Meow and Liz Parrish #BDYHAX2018 https://pbs.twimg.com/media/DVJCRU1UQAAbEuk.jpg (@kristenvbrown)
17:24 < kanzure> .tw https://twitter.com/MarkSchmidty/status/959883427574099969
17:24 < yoleaux> TIL @StelarcStelarc had a third hand in 1980- 38 years ago. #BDYHAX2018 #Cyborg #Transhumanism https://pbs.twimg.com/media/DVIw4LqU0AAIVwZ.jpg (@MarkSchmidty)
17:29 < kanzure> wat: ".... Now discussing "wegs" (wheels+legs)"
17:36 < Jenda`> thanks, I have seen this image in a science magazine years ago, forgot "stelarc" and therefore was unable to google it
17:50 < kanzure> the ear guy.
18:44 < kanzure> "Current status of nonviral vectors for gene therapy in China" http://diyhpl.us/~bryan/papers2/gene-therapy/Current%20status%20of%20nonviral%20vectors%20for%20gene%20therapy%20in%20China%20-%202017.pdf
18:47 < kanzure> good stuff. fun times.
18:52 < kanzure> "Activation of the Anti-Aging and Cognition-Enhancing Gene Klotho by CRISPR-dCas9 Transcriptional Effector Complex" https://link.springer.com/article/10.1007%2Fs12031-017-1011-0
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18:54 < kanzure> .tw https://twitter.com/elonmusk/status/957494364028071936
18:54 < yoleaux> The rumor that I’m secretly creating a zombie apocalypse to generate demand for flamethrowers is completely false (@elonmusk)
18:55 < kanzure> circuitpython/micropython discussion transcript thing https://hackaday.io/event/34310-circuit-python-hack-chat
18:57 < kanzure> "yes, hi, my body hack is wearing a CRT monitor as a helmet" https://twitter.com/Jenja/status/959651320419508224
18:57 < kanzure> cc jrayhawk
18:57 < kanzure> oh actually it's an old vhs-integrated television set
19:03 < kanzure> trammel's music picks for his conference https://soundcloud.com/leftrightmusic http://www.magicswordmusic.com/listen
19:06 < jrayhawk> i wonder if they broke apart the tube to do that
19:06 < jrayhawk> delicious mercury vapor
19:12 < kanzure> .title http://www.sens.org/outreach/press-releases/srf-receives-24m-ethereum-donation-from-vitalik-buterin
19:12 < yoleaux> SRF Receives $2.4M Ethereum Donation from Vitalik Buterin | SENS Research Foundation
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19:19 < kanzure> https://news.ycombinator.com/item?id=16300942
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19:42 < jrayhawk> 'treating symptoms, rather than causes, is
19:42 < jrayhawk> about the most brain-dead therapeutic approach imaginable.'
19:42 < jrayhawk> I am glad searching google for "SENS criticism" yields exactly the results I was afraid I was going to have to write
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20:46 < kanzure> sens has been around for a while is this new criticism from you
20:46 < kanzure> ?
21:11 < maaku> jrayhawk: what are you criticizing? my understanding of SENS is precisely that many of its 7 points are treating the causes of age related disease rather than treating the symptoms of the disease, which there is adequate funding for already
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21:39 < jrayhawk> every research project of theirs i look into is chasing after some extremely superficial side-effect of the metabolic syndrome
21:41 < jrayhawk> i should start a parody foundation to market mouth-guards to meth addicts so i can claim i am combating meth addiction
21:41 < jrayhawk> END TOOTH DECAY
21:48 < kanzure> joey do you have any easy single nucleotide mutations in mind for metabolism upgrades? before i sign an agreement with someone doing AAV gene therapies for me.
21:50 < kanzure> https://medium.com/@murchandamus/excited-for-schnorr-signatures-a00ee467fc5f
21:59 < jrayhawk> Nah, I don't get that far into genetics minutia. MTRR/MTHFR stuff and ApoE stuff might be fun to look into, though.
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--- Log closed Sun Feb 04 00:00:42 2018