--- Log opened Thu Apr 19 00:00:52 2018
00:11 < maaku> .title https://blog.acolyer.org/2018/04/19/darwin-a-genomics-co-processor-provides-up-to-15000x-acceleration-on-long-read-assembly/
00:11 < yoleaux> Darwin: a genomics co-processor provides up to 15,000x acceleration on long read assembly | the morning paper
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02:05 < ebowden> https://www.youtube.com/watch?v=h36fp6JZ_cQ
02:05 < ebowden> This version of the ad is very different from the last, nothing like as hilariously dodgy.
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03:09 < ebowden> maaku, that ASIC is so cool.
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03:35 < adlai> kanzure: please explain what you mean by trinary
03:36  * adlai has not studied iota closely, that fly is currently stuck in the "dagspam" mousetrap
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06:29 < kanzure> adlai: no u
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07:00 < juri_> are there places where i can get a full sequencing of my own DNA?
07:03 < CaptHindsight> by full do you mean to find out that you are 4% Irish (as most people are) or the whole thing and as a file you may peruse?
07:07 < kanzure> juri_: https://veritasgenetics.com/
07:08 < kanzure> "slow money" http://slowmoneynorcal.org/comparing-royalty-financing-to-debt-and-equity-financing/ http://slowmoneynorcal.org/royalty-financing/
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07:44 < TMA> it looks inferior to the current financing schemes... it is nearly as risky as equity while limiting upside like bonds
07:47 < TMA> it can be somewhat better than a fixed rate bond
07:50 < TMA> but then again -- if the yield will go up, the "maturity" will be sooner, which makes it unpredictable. also, the longer the "maturity" the lower the yield -- that alone is something to raise red flags.
08:13 < kanzure> not sure why this isn't called "revenue sharing"
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08:34 < kanzure> some discussion of the dna sequencing/assembler co-processor stuff https://news.ycombinator.com/item?id=16873591
09:01 < kanzure> someone should be looking at simulations of digital evolution of complex coding schemes starting from replacement codes. e.g. under what conditions do more complicated codes evolve.
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12:50 < kanzure> blort
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17:15 < adlai> trinary is not a word i've encountered before as anything other than a typo of ternary, but i doubt you're the kind of typist who blorts nonspam and then answers "no u" instead of explaining itself.
17:19 < maaku> adlai: trinary means three-valued
17:19 < kanzure> .title https://www.youtube.com/watch?v=OnencB-iIFA
17:19 < yoleaux> IARPA Molecular Information Storage (MIST) Proposers' Day - YouTube
17:20 < kanzure> adlai: it's so stupid that i really don't even want to get into it
17:21 < kanzure> adlai: i should not be responsible for having to explain the crap that comes out of iota
17:25 < gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=69c3c249 Bryan Bishop: transcript: IARPA MIST proposers' day >> http://diyhpl.us/diyhpluswiki/transcripts/2018-02-21-iarpa-mist/
17:30 < gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=9f9d6f2d Bryan Bishop: add tweeter link >> http://diyhpl.us/diyhpluswiki/transcripts/2018-02-21-iarpa-mist/
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18:47 < kanzure> alright, i want a "in favor of pro-health pro-upgrade science" article.
18:47 < kanzure> just something really basic that argues "hey instead of studying the diseased and dying, what about people that are doing unusually well?"
18:47 < fenn> there's no funding for studying healthy people
18:47 < fenn> the article you're looking for does not exist
18:48  * fenn waves his hand left to right slowly
18:56 < gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=a9531db5 Bryan Bishop: a reference for body fat distribution SNPs >> http://diyhpl.us/diyhpluswiki/genetic-modifications/
19:00 < kanzure> ok gwern doesn't know of a thing either
19:00 < kanzure> isn't this the kind of thing that nick bostrom is supposedly being paid to be doing..?
19:03 < kanzure> 19:03 <@gwern> kanzure: FHI doesn't like the blowback they've already gotten for touching lightly on it in _Superintelligence_ and elsewhere
19:03 < kanzure> -_-
19:05 < fenn> blowback for studying healthy people? what?
19:06 < kanzure> well, gwern is speaking about studying high-IQ people (the overarching rule with gwern is that he is intensely preoccupied with IQ studies)
19:07 < kanzure> and i believe at most it would have been proposed in "superintelligence", i doubt future of humoranity institute is doing any actual studies into iq
19:10 < kanzure> 19:09 < kanzure> gwern: are you certain you know of no articles or papers that argue in general terms for studying exceptionally healthy individuals as a direction of scientific inquiry?
19:10 < kanzure> 19:10 <@gwern> kanzure: maybe 'positive psychology' counts?
19:10 < kanzure> .wik positive psychology
19:10 < yoleaux> "Positive psychology is "the scientific study of what makes life most worth living", or "the scientific study of positive human functioning and flourishing on multiple levels that include the biological, personal, relational, institutional, cultural, and global dimensions of life"." — https://en.wikipedia.org/wiki/Positive_psychology
19:13 < kanzure> 19:11 <@gwern> they say something pretty similar, that regular psychology/psychiatry focuses too much on when things go wrong and how people fail, instead of on what makes happy successful healthy people flourish like they have
19:13 < kanzure> 19:11 <@gwern> I'm not quite sure what field you would call Dean Keith Simonton's stuff, but studying eminent figures of great accomplishment and influence might count
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21:01 < kanzure> http://mta.sciencecommons.org/agreements/sc/1.0/legalcode
21:03 < kanzure> http://mta.sciencecommons.org/chooser
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--- Log closed Fri Apr 20 00:00:53 2018