--- Log opened Sat Apr 28 00:00:01 2018 00:14 -!- aeiousomething [~aeiousome@unaffiliated/aeiousomething] has quit [Ping timeout: 240 seconds] 01:11 -!- poppingtonic [~brian@unaffiliated/poppingtonic] has quit [Ping timeout: 248 seconds] 01:25 < archels> .title https://www.youtube.com/watch?v=wSVlOAocn8E 01:25 < yoleaux> Film Theory: The Matrix has NO ESCAPE - YouTube 01:25 < archels> mind: blown 02:00 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has quit [Quit: SCIENTISTS PREDICT ICE AGE] 02:10 -!- sachy [~sachy@78.108.102.220] has quit [Quit: Leaving.] 02:28 -!- brujo_biologica [~brujo@pool-72-82-145-98.cmdnnj.fios.verizon.net] has joined ##hplusroadmap 03:51 -!- strages [uid11297@gateway/web/irccloud.com/x-tblzrnweqvcqkefw] has joined ##hplusroadmap 05:07 -!- brujo_biologica [~brujo@pool-72-82-145-98.cmdnnj.fios.verizon.net] has quit [Quit: leaving] 06:05 -!- Gurkenglas [~Gurkengla@dslb-178-000-215-034.178.000.pools.vodafone-ip.de] has joined ##hplusroadmap 06:05 < fenn> we should scrape the DOI resolver before they decide ransoming the data is more profitable than providing access. i don't like this single point of failure; it totally fails the tentacles of evil test 06:22 < kanzure> alright 06:36 -!- HEx1 [~HEx@hexwab.plus.com] has quit [Ping timeout: 255 seconds] 06:40 -!- HEx1 [~HEx@hexwab.plus.com] has joined ##hplusroadmap 06:45 < kanzure> .title https://github.com/greenelab/crossref 06:45 < yoleaux> GitHub - greenelab/crossref: Download metadata for all DOIs using the Crossref API 06:46 < kanzure> https://archive.org/download/crossref_doi_dump_201801 06:46 < kanzure> "Bryan Newbold used this codebase to create a MongoDB dump dated January 2018 (query date of approximately 2018-01-10), which he uploaded to the Internet Archive. His output file crossref-works.2018-01-21.json.xz contains 93,585,242 DOIs and consumes 28.9 GB compared to 87,542,370 DOIs and 7.0 GB for the crossref-works.json.xz dated 2017-03-21. This increased size is presumably due to the ... 06:46 < kanzure> ...addition of I4OC references to Crossref work records." 06:47 < kanzure> thank you lazyweb 06:54 < fenn> hmm archive.org does something tricky where they can detect wget and return 404 even though i change the user agent 06:55 < fenn> further javascript-ization of the internet 06:59 < JayDugger> Really, fenn? Any idea what? 07:01 -!- nickdegre [5e42380a@gateway/web/freenode/ip.94.66.56.10] has joined ##hplusroadmap 07:01 < fenn> they change the url with js to point to the correct url 07:06 < fenn> oh hmm it's actually this thing: huh? 07:59 < JayDugger> I read that interview. Was there anything else you wish you'd said? 08:00 < JayDugger> Did they omit something you thought was important, for example? 08:10 < kanzure> is there something specific you need from me? 08:12 -!- Gurkenglas [~Gurkengla@dslb-178-000-215-034.178.000.pools.vodafone-ip.de] has quit [Ping timeout: 264 seconds] 08:13 -!- DataPacRat [~dan@ip-173-247-141-132.user.start.ca] has joined ##hplusroadmap 08:18 -!- Gurkenglas [~Gurkengla@dslb-178-000-215-034.178.000.pools.vodafone-ip.de] has joined ##hplusroadmap 08:39 < JayDugger> No, thank you. 09:14 -!- sachy [~sachy@78.108.102.220] has joined ##hplusroadmap 09:21 -!- yashgaroth [~yashgarot@2606:6000:c308:f700:204c:91f4:8bf8:2448] has joined ##hplusroadmap 09:25 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has joined ##hplusroadmap 09:38 < gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=c6652660 Bryan Bishop: fix typo >> http://diyhpl.us/diyhpluswiki/dna/projects/ 09:38 < gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=2d11fb25 Bryan Bishop: really fix typo >> http://diyhpl.us/diyhpluswiki/dna/projects/ 12:04 < gnusha> https://secure.diyhpl.us/cgit/diyhpluswiki/commit/?id=e1f67f6c Bryan Bishop: more igem 2017 project summaries >> http://diyhpl.us/diyhpluswiki/dna/projects/ 12:41 < kanzure> hm. 12:44 -!- CandleGlow [~CandleGlo@unaffiliated/candleglow] has quit [Quit: ...and all my responses they stay the same.] 13:00 -!- redlegion [~x@gateway/tor-sasl/redlegion] has quit [Remote host closed the connection] 13:00 -!- redlegion [~x@gateway/tor-sasl/redlegion] has joined ##hplusroadmap 13:23 -!- beka [~beka@199-241-201-187.PUBLIC.monkeybrains.net] has joined ##hplusroadmap 15:24 -!- ebowden_ [~ebowden@128.250.0.209] has quit [Remote host closed the connection] 15:24 -!- ebowden [~ebowden@128.250.0.209] has joined ##hplusroadmap 16:21 -!- CaptHindsight [~2020@unaffiliated/capthindsight] has joined ##hplusroadmap 16:21 < CaptHindsight> https://www.nature.com/articles/s41557-018-0046-3 16:21 < CaptHindsight> I-motif DNA structures are formed in the nuclei of human cells 16:22 < CaptHindsight> this should be interesting 16:22 -!- sachy [~sachy@78.108.102.220] has quit [Quit: Leaving.] 16:39 < CaptHindsight> < fltrz> I meant "for really strong 3D printed composites you need 5D motion control and better fiber layout algorithms. i don't understand why nobody seems to be working on this" 16:39 < CaptHindsight> it's been on my list for a while 16:40 < CaptHindsight> I actually got tired of asking (suggesting) people to work on it 17:12 -!- TC [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has joined ##hplusroadmap 17:16 -!- hehelleshin [~talinck@cpe-174-97-113-184.cinci.res.rr.com] has quit [Ping timeout: 240 seconds] 17:19 < ebowden> If asking doesn't work, you might have to pay for it. 17:28 < CaptHindsight> I'll do it myself 17:30 < ebowden> Will that be expensive? 17:30 < CaptHindsight> expensive is like hard or difficult 17:31 < CaptHindsight> everything is expensive for cheapskates 17:32 < CaptHindsight> and everything is hard for those without the skills 17:32 < ebowden> Well, best of luck. 17:32 < CaptHindsight> cheapskates/without funds 17:33 < CaptHindsight> yeah luck 17:33 < CaptHindsight> good luck to you to 17:33 < CaptHindsight> peace out man 17:34 < CaptHindsight> man/dude/bro 17:42 < ebowden> Oh, I've noticed that methyl isocyanate is absurdly expensive on Alfa Aesar, but I suspect this is due to handling and packaging. How much would it cost per kg for someone like you? 17:42 < CaptHindsight> how mnay tons do you need? 17:43 < CaptHindsight> check with your Chinese connections 17:43 < ebowden> Assume you are using one tonne of it. 17:43 < ebowden> I have no Chinese connections, I am curious how much it would cost you. 17:45 < CaptHindsight> di water is expensive in low volume 17:45 < ebowden> Di water? 17:46 < ebowden> Oh. 17:46 < ebowden> Deionised Water. 17:47 < CaptHindsight> for anything in low volume you have to find someone who buys in high volume that is willing to sell you a little for near the price they buy it for 17:47 < CaptHindsight> otherwise there is always a big bump for small quantities 17:47 < ebowden> Of course. 17:49 < ebowden> Hmm, it looks like N-methylcarbamoyl chloride might be cheaper. 17:52 < CaptHindsight> most chems at Alfa Aesar and Sigma are 20-100x of what you can find it for at other places 17:53 < ebowden> What are you paying for apart from brand? 17:53 < ebowden> Their price hikes have always been astonishing to me. 17:54 < CaptHindsight> they keep a little of everything in stock and if they like you can have it to your door in a day or few 17:55 < ebowden> I suppose that is convenient. 17:55 < CaptHindsight> makes airport food look like bargains 17:55 < ebowden> lol 17:55 < CaptHindsight> if they sold hot dogs they would be $200ea 17:55 < ebowden> You are paying a LOT for that convenience. 17:55 < ebowden> lol 17:56 < kanzure> https://www.technologyreview.com/s/611007/researchers-are-keeping-pig-brains-alive-outside-the-body/ 17:57 < ebowden> CaptHindsight, what do you think of continuous flow reactors? 18:01 < CaptHindsight> kanzure: that was an interesting one 18:02 < CaptHindsight> no brain waves but kept alive for what another day or so? 18:03 < CaptHindsight> ebowden: they come in handy when you needs lots of something 18:03 < ebowden> I hear they are very scalable. 18:03 < ebowden> I know people who use them on the lab scale. 18:04 < ebowden> CaptHindsight, do you have any? 18:04 < CaptHindsight> hasta 18:05 < ebowden> ? 18:09 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has quit [Ping timeout: 240 seconds] 18:12 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has joined ##hplusroadmap 18:13 -!- justanotheruser [~justanoth@unaffiliated/justanotheruser] has joined ##hplusroadmap 18:14 -!- justan0theruser [~justanoth@unaffiliated/justanotheruser] has quit [Ping timeout: 255 seconds] 18:15 -!- Gurkenglas [~Gurkengla@dslb-178-000-215-034.178.000.pools.vodafone-ip.de] has quit [Ping timeout: 264 seconds] 18:17 < ebowden> CaptHindsight, making pharmaceuticals could get you executed if you both don't test them and fuck up a synth, but what about precursors? 18:24 < fenn> the captain has left the building 18:31 -!- beka [~beka@199-241-201-187.PUBLIC.monkeybrains.net] has quit [Remote host closed the connection] 18:32 -!- beka [~beka@199-241-201-187.PUBLIC.monkeybrains.net] has joined ##hplusroadmap 18:36 -!- beka [~beka@199-241-201-187.PUBLIC.monkeybrains.net] has quit [Ping timeout: 240 seconds] 18:40 -!- beka [~beka@199-241-201-187.PUBLIC.monkeybrains.net] has joined ##hplusroadmap 18:45 -!- beka [~beka@199-241-201-187.PUBLIC.monkeybrains.net] has quit [Ping timeout: 264 seconds] 18:50 -!- brujo_biologica [~brujo@pool-72-82-145-98.cmdnnj.fios.verizon.net] has joined ##hplusroadmap 18:56 -!- brujo_biologica [~brujo@pool-72-82-145-98.cmdnnj.fios.verizon.net] has quit [Ping timeout: 256 seconds] 18:59 -!- beka [~beka@noisebridge130.static.monkeybrains.net] has joined ##hplusroadmap 19:35 -!- abetusk [~abe@68.175.143.22] has joined ##hplusroadmap 19:37 -!- brujo_biologica [~brujo@pool-72-82-145-98.cmdnnj.fios.verizon.net] has joined ##hplusroadmap 19:43 -!- beka [~beka@noisebridge130.static.monkeybrains.net] has quit [Remote host closed the connection] 20:08 < kanzure> "Construction of a novel phagemid to produce custom DNA origami scaffolds " https://www.biorxiv.org/content/early/2018/04/27/309682 https://twitter.com/biorxivpreprint/status/989927259342548992 20:08 < kanzure> .tw https://twitter.com/DARPA/status/989187378530091010 20:08 < yoleaux> Our 20th podcast episode, The Genomineer, is live! Renee Wegrzyn, a program manager in DARPA’s Biological Technologies Office, discusses her efforts to tap into the promise of synthetic biology and genomics while keeping their potential perils in check. http://www.darpa.mil/about-us/podcast https://pbs.twimg.com/media/DbpMraQXUAA1PUw.jpg (@DARPA) 20:09 < kanzure> .tw https://twitter.com/AdamMarblestone/status/988809867887562752 20:09 < yoleaux> "But what if you could create neural interfaces that would act as a mirror of the mind? People could see how they thought. That’s the first step in acknowledging that we really are a very flawed form of intelligence—as awesome as we are." @bryan_johnson https://www.wsj.com/articles/brain-computer-interfaces-the-last-frontier-of-human-privacy-1524580522#_=_ (@AdamMarblestone) 20:10 -!- beka [~beka@noisebridge130.static.monkeybrains.net] has joined ##hplusroadmap 20:14 -!- beka [~beka@noisebridge130.static.monkeybrains.net] has quit [Ping timeout: 248 seconds] 20:22 < brujo_biologica> kanzure: a hardwired conscious is aan interesting but flawed idea 20:22 < brujo_biologica> "the interface made me do it! 20:22 < brujo_biologica> it!" 20:33 -!- brujo_biologica [~brujo@pool-72-82-145-98.cmdnnj.fios.verizon.net] has quit [Ping timeout: 260 seconds] 20:41 -!- yashgaroth [~yashgarot@2606:6000:c308:f700:204c:91f4:8bf8:2448] has quit [Quit: Leaving] 20:41 -!- brujo_biologica [~brujo@pool-72-82-145-98.cmdnnj.fios.verizon.net] has joined ##hplusroadmap 21:15 -!- beka [~beka@noisebridge130.static.monkeybrains.net] has joined ##hplusroadmap 21:41 -!- brujo_biologica [~brujo@pool-72-82-145-98.cmdnnj.fios.verizon.net] has quit [Ping timeout: 264 seconds] 21:52 -!- ebowden_ [~ebowden@27.0.232.171] has joined ##hplusroadmap 21:55 -!- ebowden [~ebowden@128.250.0.209] has quit [Ping timeout: 240 seconds] 21:56 -!- Malvolio [~Malvolio@unaffiliated/malvolio] has quit [Quit: *exhales sharply*] 22:03 -!- CandleGlow [~CandleGlo@unaffiliated/candleglow] has joined ##hplusroadmap 22:20 -!- CaptHindsight [~2020@unaffiliated/capthindsight] has quit [Quit: Leaving] 23:26 -!- CandleGlow [~CandleGlo@unaffiliated/candleglow] has quit [Disconnected by services] 23:26 -!- CandleGlow|2 [~CandleGlo@unaffiliated/candleglow] has joined ##hplusroadmap 23:30 -!- ebowden__ [~ebowden@27.0.232.171] has joined ##hplusroadmap 23:30 -!- ebowden_ [~ebowden@27.0.232.171] has quit [Read error: Connection reset by peer] 23:46 -!- CandleGlow|2 [~CandleGlo@unaffiliated/candleglow] has quit [Quit: ...and all my responses they stay the same.] --- Log closed Sun Apr 29 00:00:02 2018